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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for BACH2

Z-value: 0.62

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Transcription factors associated with BACH2

Gene Symbol Gene ID Gene Info
ENSG00000112182.10 BTB domain and CNC homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BACH2hg19_v2_chr6_-_91006461_91006517,
hg19_v2_chr6_-_91006627_91006641
-0.272.0e-01Click!

Activity profile of BACH2 motif

Sorted Z-values of BACH2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102668879 2.63 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr1_-_153521597 1.30 ENST00000368712.1
S100 calcium binding protein A3
chr1_-_153521714 1.29 ENST00000368713.3
S100 calcium binding protein A3
chr15_+_89182156 1.07 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr12_+_7023735 1.04 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr12_+_7023491 1.01 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr15_+_89182178 0.95 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr9_-_35112376 0.93 ENST00000488109.2
family with sequence similarity 214, member B
chr1_+_156096336 0.83 ENST00000504687.1
ENST00000473598.2
lamin A/C
chrX_-_154563889 0.82 ENST00000369449.2
ENST00000321926.4
chloride intracellular channel 2
chr15_+_89181974 0.81 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr1_+_156084461 0.78 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
lamin A/C
chr17_+_79650962 0.76 ENST00000329138.4
hepatocyte growth factor-regulated tyrosine kinase substrate
chr11_-_9781068 0.75 ENST00000500698.1
RP11-540A21.2
chr10_-_6019984 0.71 ENST00000525219.2
interleukin 15 receptor, alpha
chr19_+_38794797 0.69 ENST00000301246.5
ENST00000588605.1
chromosome 19 open reading frame 33
chr10_-_6019552 0.68 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
interleukin 15 receptor, alpha
chr3_+_48507210 0.63 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
three prime repair exonuclease 1
chr16_+_57662138 0.61 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
G protein-coupled receptor 56
chr3_+_48507621 0.60 ENST00000456089.1
three prime repair exonuclease 1
chr16_+_57662419 0.60 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
G protein-coupled receptor 56
chr11_+_12308447 0.55 ENST00000256186.2
MICAL C-terminal like
chr16_+_30077055 0.54 ENST00000564595.2
ENST00000569798.1
aldolase A, fructose-bisphosphate
chr17_-_56595196 0.54 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
myotubularin related protein 4
chr13_-_41768654 0.52 ENST00000379483.3
kelch repeat and BTB (POZ) domain containing 7
chr17_+_28256874 0.50 ENST00000541045.1
ENST00000536908.2
EF-hand calcium binding domain 5
chr17_+_55162453 0.49 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
A kinase (PRKA) anchor protein 1
chr2_+_69201705 0.48 ENST00000377938.2
gastrokine 1
chr3_+_183903811 0.48 ENST00000429586.2
ENST00000292808.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr1_+_156095951 0.47 ENST00000448611.2
ENST00000368297.1
lamin A/C
chr16_+_30077098 0.45 ENST00000395240.3
ENST00000566846.1
aldolase A, fructose-bisphosphate
chr1_+_150480551 0.43 ENST00000369049.4
ENST00000369047.4
extracellular matrix protein 1
chr10_-_6019455 0.41 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
interleukin 15 receptor, alpha
chr12_+_64845660 0.41 ENST00000331710.5
TANK-binding kinase 1
chr21_-_36421535 0.41 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
runt-related transcription factor 1
chr21_-_36421626 0.41 ENST00000300305.3
runt-related transcription factor 1
chr1_+_150480576 0.40 ENST00000346569.6
extracellular matrix protein 1
chr12_-_71182695 0.40 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr6_-_84140757 0.40 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr22_+_23077065 0.40 ENST00000390310.2
immunoglobulin lambda variable 2-18
chr11_-_65150103 0.39 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
solute carrier family 25, member 45
chr10_-_31288398 0.39 ENST00000538351.2
zinc finger protein 438
chr3_-_81792780 0.39 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr7_+_148395959 0.37 ENST00000325222.4
cullin 1
chr4_-_122085469 0.37 ENST00000057513.3
TNFAIP3 interacting protein 3
chr1_+_223889285 0.36 ENST00000433674.2
calpain 2, (m/II) large subunit
chr11_-_66103867 0.35 ENST00000424433.2
Ras and Rab interactor 1
chr1_+_19638788 0.35 ENST00000375155.3
ENST00000375153.3
ENST00000400548.2
PQ loop repeat containing 2
chr7_-_150721570 0.35 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
autophagy related 9B
chr2_-_89459813 0.35 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr10_+_121410882 0.35 ENST00000369085.3
BCL2-associated athanogene 3
chr1_-_109968973 0.34 ENST00000271308.4
ENST00000538610.1
proteasome (prosome, macropain) subunit, alpha type, 5
chrX_-_48937503 0.34 ENST00000322995.8
WD repeat domain 45
chr6_+_292051 0.33 ENST00000344450.5
dual specificity phosphatase 22
chr1_+_155107820 0.33 ENST00000484157.1
solute carrier family 50 (sugar efflux transporter), member 1
chr3_-_151034734 0.33 ENST00000260843.4
G protein-coupled receptor 87
chr22_+_20861858 0.32 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
mediator complex subunit 15
chr9_-_114246635 0.31 ENST00000338205.5
KIAA0368
chr11_+_10477733 0.31 ENST00000528723.1
adenosine monophosphate deaminase 3
chr10_+_88854926 0.31 ENST00000298784.1
ENST00000298786.4
family with sequence similarity 35, member A
chr18_+_268148 0.31 ENST00000581677.1
RP11-705O1.8
chr9_+_139921916 0.31 ENST00000314330.2
chromosome 9 open reading frame 139
chr2_-_85641162 0.30 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
capping protein (actin filament), gelsolin-like
chr12_-_76478686 0.30 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr15_-_80544547 0.29 ENST00000560778.2
RP11-2E17.1
chr5_-_75919253 0.28 ENST00000296641.4
coagulation factor II (thrombin) receptor-like 2
chr16_-_1429627 0.28 ENST00000248104.7
unkempt family zinc finger-like
chr15_+_22892663 0.28 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
cytoplasmic FMR1 interacting protein 1
chr11_-_65667997 0.28 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr4_-_146019693 0.28 ENST00000514390.1
anaphase promoting complex subunit 10
chr11_-_65667884 0.27 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr22_+_23134974 0.27 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr1_+_36621697 0.27 ENST00000373150.4
ENST00000373151.2
MAP7 domain containing 1
chr13_-_67802549 0.27 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr1_+_36621529 0.26 ENST00000316156.4
MAP7 domain containing 1
chr11_+_10476851 0.26 ENST00000396553.2
adenosine monophosphate deaminase 3
chr5_-_75919217 0.26 ENST00000504899.1
coagulation factor II (thrombin) receptor-like 2
chr10_-_71892555 0.26 ENST00000307864.1
apoptosis-inducing factor, mitochondrion-associated, 2
chr17_+_4853442 0.25 ENST00000522301.1
enolase 3 (beta, muscle)
chr11_+_5009424 0.25 ENST00000300762.1
matrix metallopeptidase 26
chr2_+_48541776 0.25 ENST00000413569.1
ENST00000340553.3
forkhead box N2
chr16_+_53133070 0.25 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr18_-_74207146 0.25 ENST00000443185.2
zinc finger protein 516
chr8_+_104384616 0.25 ENST00000520337.1
collagen triple helix repeat containing 1
chr16_-_1429674 0.24 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
unkempt family zinc finger-like
chr18_-_49557 0.24 ENST00000308911.6
Tubulin beta-8 chain-like protein LOC260334
chr17_+_30469473 0.23 ENST00000333942.6
ENST00000358365.3
ENST00000583994.1
ENST00000545287.2
ras homolog family member T1
chr7_+_100026406 0.23 ENST00000414441.1
methylphosphate capping enzyme
chr22_+_22764088 0.23 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr19_-_35981358 0.22 ENST00000484218.2
ENST00000338897.3
keratinocyte differentiation-associated protein
chr16_+_69599899 0.22 ENST00000567239.1
nuclear factor of activated T-cells 5, tonicity-responsive
chr7_-_35734730 0.22 ENST00000396081.1
ENST00000311350.3
HERPUD family member 2
chr10_+_88428206 0.21 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LIM domain binding 3
chr6_-_119031228 0.21 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
centrosomal protein 85kDa-like
chr9_-_130637244 0.20 ENST00000373156.1
adenylate kinase 1
chrX_-_48937531 0.20 ENST00000473974.1
ENST00000475880.1
ENST00000396681.4
ENST00000553851.1
ENST00000471338.1
ENST00000476728.1
ENST00000376368.2
ENST00000485908.1
ENST00000376372.3
ENST00000376358.3
WD repeat domain 45
WD repeat domain phosphoinositide-interacting protein 4
chr6_+_135818979 0.20 ENST00000421378.2
ENST00000579057.1
ENST00000436554.1
ENST00000438618.2
long intergenic non-protein coding RNA 271
chr2_+_233562015 0.19 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GRB10 interacting GYF protein 2
chr7_+_99006232 0.19 ENST00000403633.2
BUD31 homolog (S. cerevisiae)
chr17_+_30677136 0.19 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
zinc finger protein 207
chr2_+_202122703 0.18 ENST00000447616.1
ENST00000358485.4
caspase 8, apoptosis-related cysteine peptidase
chr10_+_127661942 0.18 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr16_+_30968615 0.18 ENST00000262519.8
SET domain containing 1A
chr5_+_150020240 0.17 ENST00000519664.1
synaptopodin
chr1_-_158656488 0.17 ENST00000368147.4
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr20_+_44034804 0.17 ENST00000357275.2
ENST00000372720.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_-_66103932 0.17 ENST00000311320.4
Ras and Rab interactor 1
chr15_-_99789736 0.17 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
tetratricopeptide repeat domain 23
chr6_+_31082603 0.17 ENST00000259881.9
psoriasis susceptibility 1 candidate 1
chr11_-_65149422 0.17 ENST00000526432.1
ENST00000527174.1
solute carrier family 25, member 45
chr1_-_108231101 0.17 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr9_+_140135665 0.16 ENST00000340384.4
tubulin, beta 4B class IVb
chr22_+_22712087 0.16 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr17_-_47287928 0.16 ENST00000507680.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr11_-_119993979 0.16 ENST00000524816.3
ENST00000525327.1
tripartite motif containing 29
chr16_+_28996416 0.16 ENST00000395456.2
ENST00000454369.2
linker for activation of T cells
chr11_-_64013288 0.16 ENST00000542235.1
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr12_-_53343602 0.16 ENST00000546897.1
ENST00000552551.1
keratin 8
chr22_+_22749343 0.16 ENST00000390298.2
immunoglobulin lambda variable 7-43
chr17_+_25799008 0.16 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
kinase suppressor of ras 1
chr12_-_76478446 0.16 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
nucleosome assembly protein 1-like 1
chr3_-_194090460 0.16 ENST00000428839.1
ENST00000347624.3
leucine rich repeat containing 15
chr9_+_4985228 0.15 ENST00000381652.3
Janus kinase 2
chr11_+_20620946 0.15 ENST00000525748.1
solute carrier family 6 (neurotransmitter transporter), member 5
chr19_-_46285646 0.15 ENST00000458663.2
dystrophia myotonica-protein kinase
chrX_-_129244655 0.15 ENST00000335997.7
E74-like factor 4 (ets domain transcription factor)
chr6_+_29910301 0.15 ENST00000376809.5
ENST00000376802.2
major histocompatibility complex, class I, A
chr15_+_51633826 0.15 ENST00000335449.6
gliomedin
chr5_+_110559603 0.15 ENST00000512453.1
calcium/calmodulin-dependent protein kinase IV
chr18_+_32290218 0.15 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
dystrobrevin, alpha
chrX_-_129244454 0.14 ENST00000308167.5
E74-like factor 4 (ets domain transcription factor)
chr5_+_176237478 0.14 ENST00000329542.4
unc-5 homolog A (C. elegans)
chr10_-_23003460 0.14 ENST00000376573.4
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr5_+_149877334 0.14 ENST00000523767.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr20_-_48782639 0.14 ENST00000435301.2
RP11-112L6.3
chr11_-_64013663 0.14 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr5_+_14664762 0.13 ENST00000284274.4
family with sequence similarity 105, member B
chr5_+_147582387 0.13 ENST00000325630.2
serine peptidase inhibitor, Kazal type 6
chr17_-_33390667 0.13 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr12_-_91348949 0.13 ENST00000358859.2
coiled-coil glutamate-rich protein 1
chr2_+_220144052 0.13 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DnaJ (Hsp40) homolog, subfamily B, member 2
chr19_-_39264072 0.13 ENST00000599035.1
ENST00000378626.4
lectin, galactoside-binding, soluble, 7
chr1_-_179112173 0.13 ENST00000408940.3
ENST00000504405.1
c-abl oncogene 2, non-receptor tyrosine kinase
chr20_-_634000 0.12 ENST00000381962.3
sulfiredoxin 1
chr12_-_76478417 0.12 ENST00000552342.1
nucleosome assembly protein 1-like 1
chr12_-_56101647 0.12 ENST00000347027.6
ENST00000257879.6
ENST00000257880.7
ENST00000394230.2
ENST00000394229.2
integrin, alpha 7
chr1_+_26606608 0.12 ENST00000319041.6
SH3 domain binding glutamic acid-rich protein like 3
chr19_-_10450287 0.12 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr2_+_220143989 0.12 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr12_-_76478386 0.12 ENST00000535020.2
nucleosome assembly protein 1-like 1
chr3_-_49395705 0.12 ENST00000419349.1
glutathione peroxidase 1
chr1_+_156863470 0.12 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
platelet endothelial aggregation receptor 1
chr1_-_11918988 0.12 ENST00000376468.3
natriuretic peptide B
chr2_+_113875466 0.11 ENST00000361779.3
ENST00000259206.5
ENST00000354115.2
interleukin 1 receptor antagonist
chr12_+_6644443 0.11 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr1_-_6662919 0.11 ENST00000377658.4
ENST00000377663.3
kelch-like family member 21
chr1_+_36554470 0.11 ENST00000373178.4
ADP-ribosylhydrolase like 2
chr6_-_35888905 0.11 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr12_+_64798095 0.11 ENST00000332707.5
exportin, tRNA
chr2_-_219858123 0.11 ENST00000453769.1
ENST00000295728.2
ENST00000392096.2
crystallin, beta A2
chr3_-_56502375 0.11 ENST00000288221.6
ELKS/RAB6-interacting/CAST family member 2
chr12_-_39299406 0.11 ENST00000331366.5
copine VIII
chr6_+_56819895 0.11 ENST00000370748.3
BEN domain containing 6
chr1_+_154966058 0.10 ENST00000392487.1
lens epithelial protein
chr19_+_39279838 0.10 ENST00000314980.4
lectin, galactoside-binding, soluble, 7B
chr6_+_56819773 0.10 ENST00000370750.2
BEN domain containing 6
chr12_-_7818474 0.10 ENST00000229304.4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr1_+_223889310 0.10 ENST00000434648.1
calpain 2, (m/II) large subunit
chr17_-_65362678 0.10 ENST00000357146.4
ENST00000356126.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr9_-_91793675 0.10 ENST00000375835.4
ENST00000375830.1
SHC (Src homology 2 domain containing) transforming protein 3
chr15_-_44829057 0.10 ENST00000559356.1
ENST00000560049.1
ENST00000313807.4
EIF3J antisense RNA 1 (head to head)
chr1_+_223900034 0.10 ENST00000295006.5
calpain 2, (m/II) large subunit
chr6_-_35888824 0.10 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr6_-_31704282 0.10 ENST00000375784.3
ENST00000375779.2
chloride intracellular channel 1
chr12_-_39836772 0.10 ENST00000541463.2
ENST00000361418.5
ENST00000544797.2
kinesin family member 21A
chr17_+_30469579 0.09 ENST00000354266.3
ENST00000581094.1
ENST00000394692.2
ras homolog family member T1
chr4_-_100356844 0.09 ENST00000437033.2
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr16_+_89988259 0.09 ENST00000554444.1
ENST00000556565.1
Tubulin beta-3 chain
chr22_+_22735135 0.09 ENST00000390297.2
immunoglobulin lambda variable 1-44
chr16_-_30125177 0.09 ENST00000406256.3
glycerophosphodiester phosphodiesterase domain containing 3
chr1_-_27816641 0.09 ENST00000430629.2
WAS protein family, member 2
chr5_-_175843524 0.09 ENST00000502877.1
clathrin, light chain B
chr17_-_48785216 0.09 ENST00000285243.6
ankyrin repeat domain 40
chr13_-_36429763 0.09 ENST00000379893.1
doublecortin-like kinase 1
chr19_-_36019123 0.09 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr9_-_139922631 0.08 ENST00000341511.6
ATP-binding cassette, sub-family A (ABC1), member 2
chr19_-_51538148 0.08 ENST00000319590.4
ENST00000250351.4
kallikrein-related peptidase 12
chr12_-_56122426 0.08 ENST00000551173.1
CD63 molecule
chr19_-_51538118 0.08 ENST00000529888.1
kallikrein-related peptidase 12
chr6_+_56820018 0.08 ENST00000370746.3
BEN domain containing 6
chr5_-_137911049 0.08 ENST00000297185.3
heat shock 70kDa protein 9 (mortalin)
chr9_-_139922726 0.08 ENST00000265662.5
ENST00000371605.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr17_-_28257080 0.08 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr5_+_72143988 0.08 ENST00000506351.2
transportin 1
chr3_+_112930387 0.08 ENST00000485230.1
BOC cell adhesion associated, oncogene regulated
chr19_-_55881741 0.08 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
interleukin 11
chr10_+_45455207 0.08 ENST00000334940.6
ENST00000374417.2
ENST00000340258.5
ENST00000427758.1
Ras association (RalGDS/AF-6) domain family member 4
chr9_+_4985016 0.08 ENST00000539801.1
Janus kinase 2
chr20_+_48909240 0.08 ENST00000371639.3
RP11-290F20.1
chr3_-_49823941 0.07 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
inositol hexakisphosphate kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 2.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.3 GO:1901656 glycoside transport(GO:1901656)
0.1 0.4 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.6 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.1 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.6 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 3.4 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 2.5 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.1 0.8 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.5 GO:0014894 response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.2 GO:0052056 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.3 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.8 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.6 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.3 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.1 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 1.2 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.0 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.3 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.5 GO:0051482 positive regulation of Rho protein signal transduction(GO:0035025) positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.0 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 0.8 GO:0033565 ESCRT-0 complex(GO:0033565)
0.2 2.1 GO:0005638 lamin filament(GO:0005638)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 2.9 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 2.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.4 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.0 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 1.6 GO:0004896 cytokine receptor activity(GO:0004896)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 3.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)