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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for BCL6B

Z-value: 0.45

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Transcription factors associated with BCL6B

Gene Symbol Gene ID Gene Info
BCL6B
ENSG00000161940.6 BCL6B transcription repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL6Bhg19_v2_chr17_+_6926339_6926377-0.242.5e-01Click!

Activity profile of BCL6B motif

Sorted Z-values of BCL6B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_42877726 1.78 ENST00000548696.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr12_-_42877764 1.67 ENST00000455697.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr15_-_52944231 0.89 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr1_+_221051699 0.77 ENST00000366903.6
HLX
H2.0-like homeobox
chr1_-_76398077 0.71 ENST00000284142.6
ASB17
ankyrin repeat and SOCS box containing 17
chr5_-_172198190 0.71 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr13_-_33112823 0.58 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr1_+_84609944 0.57 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_+_19358228 0.49 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr13_-_72441315 0.44 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr18_+_6834472 0.41 ENST00000581099.1
ENST00000419673.2
ENST00000531294.1
ARHGAP28
Rho GTPase activating protein 28
chr14_-_30396948 0.38 ENST00000331968.5
PRKD1
protein kinase D1
chr4_-_99578776 0.37 ENST00000515287.1
TSPAN5
tetraspanin 5
chr12_-_10007448 0.36 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr12_+_20522179 0.36 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr6_-_28303901 0.35 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr3_-_23958402 0.34 ENST00000415901.2
ENST00000416026.2
ENST00000412028.1
ENST00000388759.3
ENST00000437230.1
NKIRAS1
NFKB inhibitor interacting Ras-like 1
chr3_-_23958506 0.33 ENST00000425478.2
NKIRAS1
NFKB inhibitor interacting Ras-like 1
chr13_-_28194541 0.33 ENST00000316334.3
LNX2
ligand of numb-protein X 2
chr4_+_86396265 0.32 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr13_+_20207782 0.29 ENST00000414242.2
ENST00000361479.5
MPHOSPH8
M-phase phosphoprotein 8
chr5_+_72251793 0.29 ENST00000430046.2
ENST00000341845.6
FCHO2
FCH domain only 2
chr19_+_11200038 0.27 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chr12_+_93964746 0.26 ENST00000536696.2
SOCS2
suppressor of cytokine signaling 2
chr2_+_120189422 0.26 ENST00000306406.4
TMEM37
transmembrane protein 37
chr4_-_99578789 0.26 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr4_+_69313145 0.25 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr13_-_41768654 0.24 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chrX_-_135338503 0.24 ENST00000370663.5
MAP7D3
MAP7 domain containing 3
chr12_-_11175219 0.23 ENST00000390673.2
TAS2R19
taste receptor, type 2, member 19
chr12_-_43945724 0.23 ENST00000389420.3
ENST00000553158.1
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr12_-_120687948 0.22 ENST00000458477.2
PXN
paxillin
chrX_-_57147748 0.21 ENST00000374910.3
SPIN2B
spindlin family, member 2B
chr4_+_86396321 0.21 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr5_+_140535577 0.21 ENST00000539533.1
PCDHB17
Protocadherin-psi1; Uncharacterized protein
chr15_+_45003675 0.20 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr7_+_74072011 0.20 ENST00000324896.4
ENST00000353920.4
ENST00000346152.4
ENST00000416070.1
GTF2I
general transcription factor IIi
chr21_+_17102311 0.20 ENST00000285679.6
ENST00000351097.5
ENST00000285681.2
ENST00000400183.2
USP25
ubiquitin specific peptidase 25
chr10_-_70287231 0.20 ENST00000609923.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr14_-_25103388 0.19 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr19_-_49314269 0.19 ENST00000545387.2
ENST00000316273.6
ENST00000402551.1
ENST00000598162.1
ENST00000599246.1
BCAT2
branched chain amino-acid transaminase 2, mitochondrial
chr14_-_25103472 0.19 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr4_+_89378261 0.19 ENST00000264350.3
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr16_-_67517716 0.19 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr4_-_1670632 0.18 ENST00000461064.1
FAM53A
family with sequence similarity 53, member A
chr11_+_123986069 0.18 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr17_-_54893250 0.18 ENST00000397862.2
C17orf67
chromosome 17 open reading frame 67
chr7_+_23719749 0.18 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
FAM221A
family with sequence similarity 221, member A
chr2_+_87754989 0.18 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr2_+_87754887 0.17 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
LINC00152
long intergenic non-protein coding RNA 152
chr3_-_50649192 0.17 ENST00000443053.2
ENST00000348721.3
CISH
cytokine inducible SH2-containing protein
chr2_+_87755054 0.16 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr2_-_188419200 0.16 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chrX_-_54209640 0.15 ENST00000375180.2
ENST00000328235.4
ENST00000477084.1
FAM120C
family with sequence similarity 120C
chr5_+_140579162 0.15 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chr14_+_31028329 0.15 ENST00000206595.6
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr11_-_128775592 0.15 ENST00000310799.3
C11orf45
chromosome 11 open reading frame 45
chr12_-_55367361 0.15 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1
thymocyte expressed, positive selection associated 1
chr18_-_52989217 0.15 ENST00000570287.2
TCF4
transcription factor 4
chr4_+_86699834 0.15 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr21_+_17909594 0.15 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr19_-_47616992 0.14 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chr3_+_185046676 0.14 ENST00000428617.1
ENST00000443863.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr12_-_122238913 0.14 ENST00000537157.1
AC084018.1
AC084018.1
chr3_+_156799587 0.14 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr20_-_4229721 0.13 ENST00000379453.4
ADRA1D
adrenoceptor alpha 1D
chr14_+_31028348 0.13 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr12_-_62997214 0.13 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr4_-_153303658 0.13 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr17_+_38497640 0.13 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr14_+_75988851 0.12 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr6_+_35995552 0.12 ENST00000468133.1
MAPK14
mitogen-activated protein kinase 14
chr13_-_41345277 0.12 ENST00000323563.6
MRPS31
mitochondrial ribosomal protein S31
chr6_+_35995531 0.11 ENST00000229794.4
MAPK14
mitogen-activated protein kinase 14
chr17_+_4853442 0.11 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr6_+_35995488 0.11 ENST00000229795.3
MAPK14
mitogen-activated protein kinase 14
chr5_+_54398463 0.11 ENST00000274306.6
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr5_+_72251857 0.11 ENST00000507345.2
ENST00000512348.1
ENST00000287761.6
FCHO2
FCH domain only 2
chr1_+_153175900 0.11 ENST00000368747.1
LELP1
late cornified envelope-like proline-rich 1
chr7_-_99679324 0.11 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3
zinc finger protein 3
chr3_-_112329110 0.10 ENST00000479368.1
CCDC80
coiled-coil domain containing 80
chr20_-_18447667 0.10 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
DZANK1
double zinc ribbon and ankyrin repeat domains 1
chr15_+_65843130 0.10 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr3_+_158787041 0.10 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr2_-_55237484 0.10 ENST00000394609.2
RTN4
reticulon 4
chr13_+_52436111 0.09 ENST00000242819.4
CCDC70
coiled-coil domain containing 70
chr7_+_872107 0.09 ENST00000405266.1
ENST00000401592.1
ENST00000403868.1
ENST00000425407.2
SUN1
Sad1 and UNC84 domain containing 1
chr12_-_123201337 0.09 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr19_+_55128576 0.09 ENST00000396331.1
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr2_+_27805880 0.09 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512
zinc finger protein 512
chr10_-_48416849 0.09 ENST00000249598.1
GDF2
growth differentiation factor 2
chr18_-_52989525 0.09 ENST00000457482.3
TCF4
transcription factor 4
chr13_+_73356197 0.09 ENST00000326291.6
PIBF1
progesterone immunomodulatory binding factor 1
chr3_-_187455680 0.08 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr19_-_44860820 0.08 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
ZNF112
zinc finger protein 112
chr12_-_11002063 0.08 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr19_-_4831701 0.07 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr7_+_21582638 0.07 ENST00000409508.3
ENST00000328843.6
DNAH11
dynein, axonemal, heavy chain 11
chr11_+_61159832 0.07 ENST00000334888.5
ENST00000398979.3
TMEM216
transmembrane protein 216
chr22_-_50699701 0.07 ENST00000395780.1
MAPK12
mitogen-activated protein kinase 12
chr7_-_29186008 0.07 ENST00000396276.3
ENST00000265394.5
CPVL
carboxypeptidase, vitellogenic-like
chr12_+_8975061 0.07 ENST00000299698.7
A2ML1
alpha-2-macroglobulin-like 1
chr17_+_76183432 0.07 ENST00000591256.1
ENST00000589256.1
ENST00000588800.1
ENST00000591952.1
ENST00000327898.5
ENST00000586542.1
ENST00000586731.1
AFMID
arylformamidase
chr17_+_66539369 0.07 ENST00000600820.1
AC079210.1
Uncharacterized protein; cDNA FLJ45097 fis, clone BRAWH3031054
chr1_-_54405773 0.06 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr2_-_175499294 0.06 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr17_+_4981535 0.06 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr12_-_12674032 0.06 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr12_+_104324112 0.05 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr12_+_16064106 0.05 ENST00000428559.2
DERA
deoxyribose-phosphate aldolase (putative)
chr1_-_41131326 0.05 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr3_+_155860751 0.05 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr9_-_86322831 0.05 ENST00000257468.7
UBQLN1
ubiquilin 1
chr13_-_33112899 0.05 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
N4BP2L2
NEDD4 binding protein 2-like 2
chr12_-_122985067 0.05 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr12_-_122985494 0.05 ENST00000336229.4
ZCCHC8
zinc finger, CCHC domain containing 8
chr1_-_212004090 0.04 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr1_-_193029192 0.04 ENST00000417752.1
ENST00000367452.4
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr12_+_16500037 0.04 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chr17_+_34312621 0.04 ENST00000591669.1
CTB-186H2.3
Uncharacterized protein
chrX_+_78426469 0.04 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chrX_-_30993201 0.04 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr17_+_79761997 0.04 ENST00000400723.3
ENST00000570996.1
GCGR
glucagon receptor
chr4_-_155511887 0.04 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr3_+_23958470 0.04 ENST00000434031.2
ENST00000413699.1
ENST00000456530.2
RPL15
ribosomal protein L15
chr16_-_18441131 0.04 ENST00000339303.5
NPIPA8
nuclear pore complex interacting protein family, member A8
chr6_+_125540951 0.04 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr11_-_18258342 0.04 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr5_-_140700322 0.04 ENST00000313368.5
TAF7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr2_-_216257849 0.03 ENST00000456923.1
FN1
fibronectin 1
chr20_+_58251716 0.03 ENST00000355648.4
PHACTR3
phosphatase and actin regulator 3
chr6_+_7541845 0.03 ENST00000418664.2
DSP
desmoplakin
chr1_+_235530675 0.03 ENST00000366601.3
ENST00000406207.1
ENST00000543662.1
TBCE
tubulin folding cofactor E
chr1_+_111991474 0.03 ENST00000369722.3
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr19_-_460996 0.03 ENST00000264554.6
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr13_-_44980021 0.03 ENST00000432701.2
ENST00000607312.1
LINC01071
long intergenic non-protein coding RNA 1071
chr6_+_42584847 0.03 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr18_-_66382289 0.03 ENST00000443099.2
ENST00000562706.1
ENST00000544714.2
TMX3
thioredoxin-related transmembrane protein 3
chr15_-_49913126 0.03 ENST00000561064.1
ENST00000299338.6
FAM227B
family with sequence similarity 227, member B
chr6_+_44194762 0.03 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr17_-_9694614 0.03 ENST00000330255.5
ENST00000571134.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr16_+_16481598 0.02 ENST00000327792.5
NPIPA7
nuclear pore complex interacting protein family, member A7
chr6_+_7541808 0.02 ENST00000379802.3
DSP
desmoplakin
chrX_+_134847370 0.02 ENST00000482795.1
CT45A1
cancer/testis antigen family 45, member A1
chr7_-_122840015 0.02 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr1_-_168698433 0.02 ENST00000367817.3
DPT
dermatopontin
chr8_-_102216925 0.02 ENST00000517844.1
ZNF706
zinc finger protein 706
chr11_+_120081475 0.02 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr6_+_39760129 0.02 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr4_+_95972822 0.02 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chrX_+_95939711 0.01 ENST00000373049.4
ENST00000324765.8
DIAPH2
diaphanous-related formin 2
chr6_-_29324054 0.01 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr11_+_58874701 0.01 ENST00000529618.1
ENST00000534403.1
ENST00000343597.3
FAM111B
family with sequence similarity 111, member B
chr12_+_31812121 0.01 ENST00000395763.3
METTL20
methyltransferase like 20
chr12_-_91574142 0.01 ENST00000547937.1
DCN
decorin
chr2_+_169658928 0.01 ENST00000317647.7
ENST00000445023.2
NOSTRIN
nitric oxide synthase trafficking
chr8_-_130799134 0.01 ENST00000276708.4
GSDMC
gasdermin C
chr10_+_18240834 0.01 ENST00000377371.3
ENST00000539911.1
SLC39A12
solute carrier family 39 (zinc transporter), member 12
chrX_-_134936550 0.01 ENST00000494421.1
CT45A4
cancer/testis antigen family 45, member A4
chr3_+_23959185 0.01 ENST00000354811.5
RPL15
ribosomal protein L15
chr19_-_7812397 0.01 ENST00000593660.1
ENST00000354397.6
ENST00000593821.1
ENST00000602261.1
ENST00000315591.8
ENST00000394161.5
ENST00000204801.8
ENST00000601256.1
ENST00000601951.1
ENST00000315599.7
CD209
CD209 molecule
chrX_+_135570046 0.01 ENST00000370648.3
BRS3
bombesin-like receptor 3
chr2_-_188419078 0.01 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chrX_-_134971059 0.01 ENST00000472834.1
CT45A6
cancer/testis antigen family 45, member A6
chr1_-_74663825 0.01 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
LRRIQ3
leucine-rich repeats and IQ motif containing 3
chr1_-_108735440 0.01 ENST00000370041.4
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr3_+_23958632 0.01 ENST00000412097.1
ENST00000415719.1
ENST00000435882.1
RPL15
ribosomal protein L15
chr8_-_81787006 0.01 ENST00000327835.3
ZNF704
zinc finger protein 704
chr15_+_69854027 0.00 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr7_+_2636522 0.00 ENST00000423196.1
IQCE
IQ motif containing E
chr6_+_150690028 0.00 ENST00000229447.5
ENST00000344419.3
IYD
iodotyrosine deiodinase
chr11_-_104480019 0.00 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr17_-_39296739 0.00 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr14_+_101123580 0.00 ENST00000556697.1
ENST00000360899.2
ENST00000553623.1
LINC00523
long intergenic non-protein coding RNA 523
chrX_+_79675965 0.00 ENST00000308293.5
FAM46D
family with sequence similarity 46, member D
chr19_-_40023450 0.00 ENST00000326282.4
EID2B
EP300 interacting inhibitor of differentiation 2B

Network of associatons between targets according to the STRING database.

First level regulatory network of BCL6B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.9 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.6 GO:0097338 response to clozapine(GO:0097338)
0.1 0.6 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.3 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.2 GO:1904432 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.2 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 0.4 GO:0071321 cellular response to cGMP(GO:0071321)
0.1 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:2001191 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0 0.0 GO:2001202 negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 0.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.1 GO:0070197 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID IGF1 PATHWAY IGF1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport