Project
Inflammatory response time course, HUVEC (Wada et al., 2009)
Navigation
Downloads
Results for BPTF
Z-value: 1.68
Motif logo
Transcription factors associated with BPTF
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BPTF | hg19_v2_chr17_+_65821636_65821641 | 0.46 | 2.0e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_-_150329421 Show fit | 6.47 |
ENST00000493969.1
ENST00000328902.5 |
GTPase, IMAP family member 6 |
|
| chr4_-_159080806 Show fit | 5.60 |
ENST00000590648.1
|
family with sequence similarity 198, member B |
|
| chr4_+_156588115 Show fit | 5.51 |
ENST00000455639.2
|
guanylate cyclase 1, soluble, alpha 3 |
|
| chr4_-_186877806 Show fit | 5.49 |
ENST00000355634.5
|
sorbin and SH3 domain containing 2 |
|
| chr4_+_41614909 Show fit | 4.73 |
ENST00000509454.1
ENST00000396595.3 ENST00000381753.4 |
LIM and calponin homology domains 1 |
|
| chr3_-_112127981 Show fit | 4.73 |
ENST00000486726.2
|
RP11-231E6.1 |
|
| chr4_+_156587979 Show fit | 3.98 |
ENST00000511507.1
|
guanylate cyclase 1, soluble, alpha 3 |
|
| chr4_+_156588249 Show fit | 3.91 |
ENST00000393832.3
|
guanylate cyclase 1, soluble, alpha 3 |
|
| chr4_+_156587853 Show fit | 3.73 |
ENST00000506455.1
ENST00000511108.1 |
guanylate cyclase 1, soluble, alpha 3 |
|
| chr4_+_41614720 Show fit | 3.47 |
ENST00000509277.1
|
LIM and calponin homology domains 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of BPTF
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 17.1 | GO:0052565 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 0.3 | 9.8 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 8.9 | GO:0007286 | spermatid development(GO:0007286) |
| 0.0 | 6.3 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 6.2 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 1.0 | 5.1 | GO:2000470 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.0 | 4.8 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
| 0.7 | 4.7 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 1.2 | 3.5 | GO:0014839 | myoblast migration involved in skeletal muscle regeneration(GO:0014839) |
| 0.3 | 3.5 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 17.0 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 15.8 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.4 | 8.6 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 6.8 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 6.4 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 6.1 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 5.8 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 5.6 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 5.0 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.5 | 4.8 | GO:0042382 | paraspeckles(GO:0042382) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 17.0 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.3 | 9.8 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 9.3 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 7.2 | GO:0003779 | actin binding(GO:0003779) |
| 0.5 | 7.0 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 1.0 | 5.1 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.1 | 4.8 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 4.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 4.3 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 3.7 | GO:0005525 | GTP binding(GO:0005525) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.7 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 9.8 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 5.0 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 5.0 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 4.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 4.3 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.4 | 4.0 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.1 | 3.6 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 3.5 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 3.0 | PID ATM PATHWAY | ATM pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 15.2 | REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.2 | 8.7 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 5.6 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 4.1 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 3.8 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.1 | 3.8 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 3.8 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 3.6 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.1 | 3.4 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 3.3 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |