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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CCAGUGU

Z-value: 0.61

Motif logo

miRNA associated with seed CCAGUGU

NamemiRBASE accession
MIMAT0000231
MIMAT0000263

Activity profile of CCAGUGU motif

Sorted Z-values of CCAGUGU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_23386305 2.13 ENST00000519973.1
solute carrier family 25 (mitochondrial iron transporter), member 37
chr8_+_23430157 2.11 ENST00000399967.3
FP15737
chr1_+_218519577 1.57 ENST00000366930.4
ENST00000366929.4
transforming growth factor, beta 2
chr10_-_105615164 1.45 ENST00000355946.2
ENST00000369774.4
SH3 and PX domains 2A
chr5_-_59189545 1.15 ENST00000340635.6
phosphodiesterase 4D, cAMP-specific
chr8_+_104311059 1.12 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
frizzled family receptor 6
chr6_-_137113604 1.07 ENST00000359015.4
mitogen-activated protein kinase kinase kinase 5
chr7_-_131241361 1.02 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
podocalyxin-like
chr15_+_80987617 0.96 ENST00000258884.4
ENST00000558464.1
abhydrolase domain containing 17C
chr8_-_8751068 0.96 ENST00000276282.6
malignant fibrous histiocytoma amplified sequence 1
chr12_+_102271129 0.90 ENST00000258534.8
DNA-damage regulated autophagy modulator 1
chr12_+_121570631 0.89 ENST00000546057.1
ENST00000377162.2
ENST00000328963.5
ENST00000535250.1
ENST00000541446.1
purinergic receptor P2X, ligand-gated ion channel, 7
chr2_+_99953816 0.77 ENST00000289371.6
eukaryotic translation initiation factor 5B
chr1_-_89531041 0.73 ENST00000370473.4
guanylate binding protein 1, interferon-inducible
chr14_+_103243813 0.71 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TNF receptor-associated factor 3
chr6_+_44094627 0.67 ENST00000259746.9
transmembrane protein 63B
chr6_+_10556215 0.67 ENST00000316170.3
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr11_-_128392085 0.66 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr10_-_121296045 0.63 ENST00000392865.1
regulator of G-protein signaling 10
chr22_-_18507279 0.60 ENST00000441493.2
ENST00000444520.1
ENST00000207726.7
ENST00000429452.1
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr3_-_189838670 0.59 ENST00000319332.5
leprecan-like 1
chr7_-_139763521 0.59 ENST00000263549.3
poly (ADP-ribose) polymerase family, member 12
chr22_-_42017021 0.58 ENST00000263256.6
desumoylating isopeptidase 1
chr2_+_23608064 0.57 ENST00000486442.1
kelch-like family member 29
chr16_+_11762270 0.55 ENST00000329565.5
stannin
chr10_-_62149433 0.54 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr1_-_39325431 0.54 ENST00000373001.3
Ras-related GTP binding C
chr19_+_13906250 0.54 ENST00000254323.2
zinc finger, SWIM-type containing 4
chr10_+_111767720 0.54 ENST00000356080.4
ENST00000277900.8
adducin 3 (gamma)
chr16_+_31044812 0.52 ENST00000313843.3
syntaxin 4
chr12_+_72148614 0.50 ENST00000261263.3
RAB21, member RAS oncogene family
chr2_-_153574480 0.49 ENST00000410080.1
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr1_+_182992545 0.49 ENST00000258341.4
laminin, gamma 1 (formerly LAMB2)
chr17_+_74261277 0.49 ENST00000327490.6
UBA-like domain containing 2
chr1_-_231473578 0.49 ENST00000360394.2
ENST00000366645.1
exocyst complex component 8
chr5_+_98104978 0.49 ENST00000308234.7
repulsive guidance molecule family member b
chr1_+_27561007 0.48 ENST00000319394.3
WD and tetratricopeptide repeats 1
chr13_+_95254085 0.48 ENST00000376958.4
G protein-coupled receptor 180
chr19_-_16682987 0.48 ENST00000431408.1
ENST00000436553.2
ENST00000595753.1
solute carrier family 35, member E1
chr4_+_140222609 0.47 ENST00000296543.5
ENST00000398947.1
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr19_-_58662139 0.46 ENST00000598312.1
zinc finger protein 329
chr20_-_14318248 0.46 ENST00000378053.3
ENST00000341420.4
fibronectin leucine rich transmembrane protein 3
chr20_-_4804244 0.45 ENST00000379400.3
Ras association (RalGDS/AF-6) domain family member 2
chr1_-_21671968 0.44 ENST00000415912.2
endothelin converting enzyme 1
chr12_-_56652111 0.44 ENST00000267116.7
ankyrin repeat domain 52
chr9_-_94186131 0.42 ENST00000297689.3
nuclear factor, interleukin 3 regulated
chr17_-_79919154 0.42 ENST00000409678.3
notum pectinacetylesterase homolog (Drosophila)
chr21_+_40177143 0.41 ENST00000360214.3
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr1_-_156023580 0.41 ENST00000368309.3
ubiquilin 4
chr9_-_128003606 0.40 ENST00000324460.6
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr18_+_55102917 0.40 ENST00000491143.2
one cut homeobox 2
chr20_-_10654639 0.39 ENST00000254958.5
jagged 1
chr16_-_23160591 0.39 ENST00000219689.7
ubiquitin specific peptidase 31
chr19_+_45349432 0.38 ENST00000252485.4
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr3_-_160283348 0.38 ENST00000334256.4
karyopherin alpha 4 (importin alpha 3)
chr7_+_100770328 0.37 ENST00000223095.4
ENST00000445463.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr17_-_61777459 0.37 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr3_+_186648274 0.37 ENST00000169298.3
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr3_+_38495333 0.36 ENST00000352511.4
activin A receptor, type IIB
chr11_-_118661828 0.36 ENST00000264018.4
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr17_-_27621125 0.35 ENST00000579665.1
ENST00000225388.4
nuclear fragile X mental retardation protein interacting protein 2
chr20_+_48599506 0.35 ENST00000244050.2
snail family zinc finger 1
chr14_-_91884115 0.35 ENST00000389857.6
coiled-coil domain containing 88C
chr19_-_56092187 0.34 ENST00000325421.4
ENST00000592239.1
zinc finger protein 579
chr2_+_26256938 0.34 ENST00000264710.4
RAB10, member RAS oncogene family
chr15_+_90544532 0.32 ENST00000268154.4
zinc finger protein 710
chr2_-_213403565 0.32 ENST00000342788.4
ENST00000436443.1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr9_-_19786926 0.30 ENST00000341998.2
ENST00000286344.3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr10_+_98592009 0.29 ENST00000540664.1
ENST00000371103.3
ligand dependent nuclear receptor corepressor
chr2_-_242212227 0.29 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
high density lipoprotein binding protein
chr9_+_110045537 0.28 ENST00000358015.3
RAD23 homolog B (S. cerevisiae)
chr14_+_67707826 0.28 ENST00000261681.4
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr17_+_27717415 0.27 ENST00000583121.1
ENST00000261716.3
TAO kinase 1
chr1_+_28995231 0.27 ENST00000373816.1
glucocorticoid modulatory element binding protein 1
chr4_-_23891693 0.26 ENST00000264867.2
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chrX_-_73834449 0.26 ENST00000332687.6
ENST00000349225.2
ring finger protein, LIM domain interacting
chr15_+_64680003 0.26 ENST00000261884.3
thyroid hormone receptor interactor 4
chr15_-_42264702 0.26 ENST00000220325.4
EH-domain containing 4
chr17_-_27916621 0.25 ENST00000225394.3
G protein-coupled receptor kinase interacting ArfGAP 1
chr1_+_15943995 0.25 ENST00000480945.1
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr1_+_51701924 0.25 ENST00000242719.3
ring finger protein 11
chr10_-_71930222 0.24 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1 homolog A (S. cerevisiae)
chr4_+_184826418 0.24 ENST00000308497.4
ENST00000438269.1
storkhead box 2
chr4_-_53525406 0.24 ENST00000451218.2
ENST00000441222.3
ubiquitin specific peptidase 46
chr7_-_151217001 0.24 ENST00000262187.5
Ras homolog enriched in brain
chr16_-_67840442 0.24 ENST00000536251.1
ENST00000448631.2
ENST00000602677.1
ENST00000411657.2
ENST00000425512.2
ENST00000317506.3
RAN binding protein 10
chrX_-_103087136 0.24 ENST00000243298.2
RAB9B, member RAS oncogene family
chr20_+_43595115 0.23 ENST00000372806.3
ENST00000396731.4
ENST00000372801.1
ENST00000499879.2
serine/threonine kinase 4
chr19_-_11039261 0.22 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
Yip1 domain family, member 2
chr11_-_57298187 0.22 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr20_+_32951041 0.22 ENST00000374864.4
itchy E3 ubiquitin protein ligase
chr1_+_19970657 0.21 ENST00000375136.3
neuroblastoma 1, DAN family BMP antagonist
chr17_+_55162453 0.21 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
A kinase (PRKA) anchor protein 1
chr7_+_116165754 0.21 ENST00000405348.1
caveolin 1, caveolae protein, 22kDa
chr8_+_144679984 0.21 ENST00000504548.2
ENST00000321385.3
tigger transposable element derived 5
chr1_+_193091080 0.21 ENST00000367435.3
cell division cycle 73
chr1_+_107683644 0.21 ENST00000370067.1
netrin G1
chr12_-_42632016 0.21 ENST00000442791.3
ENST00000327791.4
ENST00000534854.2
ENST00000380788.3
ENST00000380790.4
YY1 associated factor 2
chrX_+_23801280 0.21 ENST00000379251.3
ENST00000379253.3
ENST00000379254.1
ENST00000379270.4
spermidine/spermine N1-acetyltransferase 1
chr10_-_120514720 0.20 ENST00000369151.3
ENST00000340214.4
CDK2-associated, cullin domain 1
chr22_-_46373004 0.20 ENST00000339464.4
wingless-type MMTV integration site family, member 7B
chr9_+_116638562 0.20 ENST00000374126.5
ENST00000288466.7
zinc finger protein 618
chr22_-_36784035 0.20 ENST00000216181.5
myosin, heavy chain 9, non-muscle
chr16_+_16043406 0.20 ENST00000399410.3
ENST00000399408.2
ENST00000346370.5
ENST00000351154.5
ENST00000345148.5
ENST00000349029.5
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr7_+_7606497 0.19 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
missing oocyte, meiosis regulator, homolog (Drosophila)
chr18_-_74207146 0.19 ENST00000443185.2
zinc finger protein 516
chr17_+_46125707 0.19 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
nuclear factor, erythroid 2-like 1
chr14_+_105267250 0.19 ENST00000342537.7
zinc finger and BTB domain containing 42
chr11_+_58346584 0.19 ENST00000316059.6
ZFP91 zinc finger protein
chr19_+_7598890 0.19 ENST00000221249.6
ENST00000601668.1
ENST00000601001.1
patatin-like phospholipase domain containing 6
chr10_+_70883908 0.18 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
vacuolar protein sorting 26 homolog A (S. pombe)
chr7_+_144052381 0.17 ENST00000498580.1
ENST00000056217.5
Rho guanine nucleotide exchange factor (GEF) 5
chr16_+_87636474 0.17 ENST00000284262.2
junctophilin 3
chr17_-_5389477 0.17 ENST00000572834.1
ENST00000570848.1
ENST00000571971.1
ENST00000158771.4
derlin 2
chr6_+_96463840 0.17 ENST00000302103.5
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr17_+_28804380 0.17 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
golgi SNAP receptor complex member 1
chr9_+_77112244 0.17 ENST00000376896.3
RAR-related orphan receptor B
chr11_-_79151695 0.17 ENST00000278550.7
teneurin transmembrane protein 4
chr10_+_60272814 0.16 ENST00000373886.3
bicaudal C homolog 1 (Drosophila)
chr8_-_91997427 0.16 ENST00000517562.2
chromosome 8 open reading frame 88
chr22_-_44258360 0.16 ENST00000330884.4
ENST00000249130.5
sulfotransferase family 4A, member 1
chr10_+_18549645 0.16 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr1_+_218458625 0.16 ENST00000366932.3
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr7_-_81399438 0.16 ENST00000222390.5
hepatocyte growth factor (hepapoietin A; scatter factor)
chr17_-_46682321 0.16 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr15_+_73976545 0.15 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276 molecule
chr6_-_107436473 0.15 ENST00000369042.1
BEN domain containing 3
chr13_+_25875662 0.15 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
nucleoporin like 1
chr3_+_174577070 0.15 ENST00000454872.1
N-acetylated alpha-linked acidic dipeptidase-like 2
chrX_+_117480036 0.15 ENST00000371822.5
ENST00000254029.3
ENST00000371825.3
WD repeat domain 44
chr6_+_41040678 0.15 ENST00000341376.6
ENST00000353205.5
nuclear transcription factor Y, alpha
chr9_+_34990219 0.15 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DnaJ (Hsp40) homolog, subfamily B, member 5
chr17_-_33448468 0.15 ENST00000591723.1
ENST00000593039.1
ENST00000587405.1
Uncharacterized protein
RAD51 paralog D
chr11_-_34379546 0.15 ENST00000435224.2
ankyrin repeat and BTB (POZ) domain containing 2
chr3_-_119813264 0.14 ENST00000264235.8
glycogen synthase kinase 3 beta
chrX_+_48916497 0.14 ENST00000496529.2
ENST00000376396.3
ENST00000422185.2
ENST00000603986.1
ENST00000536628.2
coiled-coil domain containing 120
chr22_+_25960786 0.14 ENST00000324198.6
adrenergic, beta, receptor kinase 2
chr20_+_48429356 0.14 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr14_+_20937538 0.13 ENST00000361505.5
ENST00000553591.1
purine nucleoside phosphorylase
chr5_-_132948216 0.13 ENST00000265342.7
follistatin-like 4
chr12_-_51477333 0.13 ENST00000228515.1
ENST00000548206.1
ENST00000546935.1
ENST00000548981.1
cysteine-serine-rich nuclear protein 2
chr3_-_129325660 0.13 ENST00000324093.4
ENST00000393239.1
plexin D1
chr9_-_37465396 0.13 ENST00000307750.4
zinc finger and BTB domain containing 5
chr10_-_118502070 0.12 ENST00000369209.3
heat shock 70kDa protein 12A
chr2_-_206950781 0.12 ENST00000403263.1
INO80 complex subunit D
chr22_+_41956767 0.12 ENST00000306149.7
cold shock domain containing C2, RNA binding
chr9_+_34179003 0.12 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
ubiquitin associated protein 1
chr10_-_88281494 0.12 ENST00000298767.5
wings apart-like homolog (Drosophila)
chr17_+_685513 0.12 ENST00000304478.4
RNA methyltransferase like 1
chr15_-_75871589 0.12 ENST00000306726.2
protein tyrosine phosphatase, non-receptor type 9
chr5_+_139493665 0.11 ENST00000331327.3
purine-rich element binding protein A
chr17_-_33416231 0.11 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr17_+_53342311 0.11 ENST00000226067.5
hepatic leukemia factor
chr10_+_31608054 0.11 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
zinc finger E-box binding homeobox 1
chr10_-_15762124 0.11 ENST00000378076.3
integrin, alpha 8
chr18_-_5544241 0.11 ENST00000341928.2
ENST00000540638.2
erythrocyte membrane protein band 4.1-like 3
chr12_+_11802753 0.11 ENST00000396373.4
ets variant 6
chr17_+_45727204 0.11 ENST00000290158.4
karyopherin (importin) beta 1
chr19_+_4304632 0.11 ENST00000597590.1
fibronectin type III and SPRY domain containing 1
chr17_-_3749515 0.11 ENST00000158149.3
ENST00000389005.4
chromosome 17 open reading frame 85
chr11_-_92931098 0.11 ENST00000326402.4
solute carrier family 36 (proton/amino acid symporter), member 4
chr5_-_89825328 0.10 ENST00000500869.2
ENST00000315948.6
ENST00000509384.1
LysM, putative peptidoglycan-binding, domain containing 3
chr2_-_19558373 0.10 ENST00000272223.2
odd-skipped related transciption factor 1
chr19_+_11071546 0.10 ENST00000358026.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr19_+_58258164 0.10 ENST00000317178.5
zinc finger protein 776
chr16_-_30798492 0.10 ENST00000262525.4
zinc finger protein 629
chr8_+_30241995 0.10 ENST00000397323.4
ENST00000339877.4
ENST00000320203.4
ENST00000287771.5
RNA binding protein with multiple splicing
chr3_-_14166316 0.10 ENST00000396914.3
ENST00000295767.5
coiled-coil-helix-coiled-coil-helix domain containing 4
chr12_+_104682496 0.09 ENST00000378070.4
thioredoxin reductase 1
chr19_+_39616410 0.09 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
p21 protein (Cdc42/Rac)-activated kinase 4
chr11_+_77300669 0.09 ENST00000313578.3
aquaporin 11
chr12_-_67072714 0.09 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
glutamate receptor interacting protein 1
chr3_-_57678772 0.09 ENST00000311128.5
DENN/MADD domain containing 6A
chr10_+_112679301 0.09 ENST00000265277.5
ENST00000369452.4
soc-2 suppressor of clear homolog (C. elegans)
chr16_-_4292071 0.09 ENST00000399609.3
sarcalumenin
chrX_-_54384425 0.08 ENST00000375169.3
ENST00000354646.2
WNK lysine deficient protein kinase 3
chr5_+_140079919 0.08 ENST00000274712.3
zinc finger, matrin-type 2
chr19_+_10654561 0.08 ENST00000309469.4
autophagy related 4D, cysteine peptidase
chr10_+_99496872 0.08 ENST00000337540.7
ENST00000357540.4
ENST00000370613.3
ENST00000370610.3
ENST00000393677.4
ENST00000453958.2
ENST00000359980.3
zinc finger, FYVE domain containing 27
chr16_-_62070305 0.08 ENST00000584337.1
cadherin 8, type 2
chr1_-_175161890 0.08 ENST00000545251.2
ENST00000423313.1
KIAA0040
chr5_+_178322893 0.08 ENST00000361362.2
ENST00000520660.1
ENST00000520805.1
ZFP2 zinc finger protein
chr1_-_38512450 0.08 ENST00000373012.2
POU class 3 homeobox 1
chr2_+_36582857 0.08 ENST00000280527.2
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr7_+_29234028 0.07 ENST00000222792.6
chimerin 2
chr3_-_113415441 0.07 ENST00000491165.1
ENST00000316407.4
KIAA2018
chr1_-_84972248 0.07 ENST00000370645.4
ENST00000370641.3
guanine nucleotide binding protein (G protein), gamma 5
chr15_-_65809581 0.07 ENST00000341861.5
dipeptidyl-peptidase 8
chr19_+_49660997 0.07 ENST00000598691.1
ENST00000252826.5
transient receptor potential cation channel, subfamily M, member 4
chr3_-_176914238 0.07 ENST00000430069.1
ENST00000428970.1
transducin (beta)-like 1 X-linked receptor 1
chr2_+_101436564 0.07 ENST00000335681.5
neuronal PAS domain protein 2
chr6_+_117586713 0.07 ENST00000352536.3
ENST00000326274.5
vestigial like 2 (Drosophila)
chr22_+_50247449 0.07 ENST00000216268.5
zinc finger, BED-type containing 4
chr1_-_37499726 0.07 ENST00000373091.3
ENST00000373093.4
glutamate receptor, ionotropic, kainate 3
chr1_+_160085501 0.07 ENST00000361216.3
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr16_-_4987065 0.07 ENST00000590782.2
ENST00000345988.2
periplakin
chr19_-_56135928 0.07 ENST00000591479.1
ENST00000325351.4
zinc finger protein 784
chr13_-_23949671 0.07 ENST00000402364.1
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr21_-_34960948 0.07 ENST00000453626.1
ENST00000303113.6
ENST00000432378.1
ENST00000303071.5
downstream neighbor of SON
chr18_+_32558208 0.06 ENST00000436190.2
microtubule-associated protein, RP/EB family, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CCAGUGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.5 1.6 GO:0051795 negative regulation of alkaline phosphatase activity(GO:0010693) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795)
0.4 1.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 0.9 GO:1904170 NAD transport(GO:0043132) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.3 1.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 1.5 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 0.5 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.7 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.5 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.4 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 1.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.4 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.3 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.5 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.3 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.7 GO:0030578 PML body organization(GO:0030578)
0.1 0.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.2 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.4 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.2 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.1 0.5 GO:0019236 response to pheromone(GO:0019236)
0.1 1.1 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.2 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.5 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.1 GO:1904339 superior temporal gyrus development(GO:0071109) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.2 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.0 0.5 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:1900756 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.4 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 1.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0060013 righting reflex(GO:0060013)
0.0 0.5 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:1902661 positive regulation of glucose mediated signaling pathway(GO:1902661)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.0 GO:1903570 coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.0 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0071205 protein localization to paranode region of axon(GO:0002175) protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0032968 endodermal cell fate commitment(GO:0001711) positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.0 GO:0044691 tooth eruption(GO:0044691)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.4 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.5 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.5 GO:0043260 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.1 1.0 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.8 GO:0035749 myelin sheath adaxonal region(GO:0035749) lateral loop(GO:0043219)
0.1 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.9 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.6 GO:0002102 podosome(GO:0002102)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 2.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 2.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 1.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 1.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline