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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CDC5L

Z-value: 0.65

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Transcription factors associated with CDC5L

Gene Symbol Gene ID Gene Info
CDC5L
ENSG00000096401.7 cell division cycle 5 like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDC5Lhg19_v2_chr6_+_44355257_44355315-0.096.8e-01Click!

Activity profile of CDC5L motif

Sorted Z-values of CDC5L motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_74606223 2.44 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr15_+_62359175 2.22 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chr5_-_61031495 2.22 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
CTD-2170G1.2
chr2_+_102721023 2.15 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr2_+_228678550 2.03 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr14_+_22458631 1.80 ENST00000390444.1
TRAV16
T cell receptor alpha variable 16
chr21_+_43619796 1.75 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr11_-_102651343 1.73 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr5_+_118690466 1.44 ENST00000503646.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr3_-_127541194 1.43 ENST00000453507.2
MGLL
monoglyceride lipase
chr18_+_61554932 1.32 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr4_-_76957214 1.31 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr2_-_225811747 1.31 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr6_+_32812568 1.17 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr6_+_55039050 1.08 ENST00000370862.3
HCRTR2
hypocretin (orexin) receptor 2
chr7_+_142919130 0.98 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr1_-_150738261 0.96 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr12_-_9913489 0.95 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr1_+_144339738 0.95 ENST00000538264.1
AL592284.1
Protein LOC642441
chr15_-_55562582 0.93 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr11_+_20044096 0.87 ENST00000533917.1
NAV2
neuron navigator 2
chr9_-_73029540 0.86 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr15_-_55562479 0.83 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr15_-_42076229 0.79 ENST00000597767.1
AC073657.1
Uncharacterized protein
chr6_+_127898312 0.79 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr8_+_104310661 0.76 ENST00000522566.1
FZD6
frizzled family receptor 6
chr1_-_65468148 0.67 ENST00000415842.1
RP11-182I10.3
RP11-182I10.3
chr7_-_122339162 0.67 ENST00000340112.2
RNF133
ring finger protein 133
chr14_-_53331239 0.65 ENST00000553663.1
FERMT2
fermitin family member 2
chrX_-_45629661 0.64 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
RP6-99M1.2
chr21_+_33784670 0.61 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr7_+_134430212 0.61 ENST00000436461.2
CALD1
caldesmon 1
chr2_+_162087577 0.60 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr7_+_55177416 0.59 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr5_-_133510456 0.59 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr12_-_39734783 0.58 ENST00000552961.1
KIF21A
kinesin family member 21A
chr12_+_21207503 0.57 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr12_+_20968608 0.57 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr12_+_21168630 0.56 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr13_+_111855414 0.56 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr8_+_104311059 0.55 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
FZD6
frizzled family receptor 6
chr2_+_127413481 0.55 ENST00000259254.4
GYPC
glycophorin C (Gerbich blood group)
chr1_-_85870177 0.53 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr15_-_55611306 0.53 ENST00000563262.1
RAB27A
RAB27A, member RAS oncogene family
chr20_-_30539773 0.53 ENST00000202017.4
PDRG1
p53 and DNA-damage regulated 1
chr1_-_89591749 0.51 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr10_-_106098162 0.51 ENST00000337478.1
ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr12_-_58165870 0.50 ENST00000257848.7
METTL1
methyltransferase like 1
chr3_-_108672609 0.50 ENST00000393963.3
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr6_+_12717892 0.48 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr20_-_45061695 0.48 ENST00000445496.2
ELMO2
engulfment and cell motility 2
chr17_-_7493390 0.46 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15
SRY (sex determining region Y)-box 15
chr22_+_30821732 0.46 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr9_-_136214877 0.45 ENST00000446777.1
ENST00000343730.5
ENST00000344469.5
ENST00000371999.1
ENST00000494177.2
ENST00000457204.2
MED22
mediator complex subunit 22
chr5_-_146781153 0.45 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr3_+_57882024 0.44 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr2_-_113542063 0.44 ENST00000263339.3
IL1A
interleukin 1, alpha
chr11_-_62609281 0.44 ENST00000525239.1
ENST00000538098.2
WDR74
WD repeat domain 74
chr12_-_91546926 0.42 ENST00000550758.1
DCN
decorin
chr17_-_76713100 0.41 ENST00000585509.1
CYTH1
cytohesin 1
chr8_-_87242589 0.41 ENST00000419776.2
ENST00000297524.3
SLC7A13
solute carrier family 7 (anionic amino acid transporter), member 13
chr4_+_155484155 0.40 ENST00000509493.1
FGB
fibrinogen beta chain
chr18_+_55888767 0.39 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_-_13517565 0.39 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr3_+_57881966 0.39 ENST00000495364.1
SLMAP
sarcolemma associated protein
chrM_+_12331 0.39 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr5_-_16738451 0.39 ENST00000274203.9
ENST00000515803.1
MYO10
myosin X
chr1_-_86043921 0.39 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr12_+_10331605 0.38 ENST00000298530.3
TMEM52B
transmembrane protein 52B
chr4_-_68749699 0.38 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr5_+_140762268 0.38 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr4_-_68749745 0.38 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr18_-_31628558 0.38 ENST00000535384.1
NOL4
nucleolar protein 4
chr7_+_151038850 0.38 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr3_-_122283424 0.38 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr5_+_54320078 0.37 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr7_+_134551583 0.37 ENST00000435928.1
CALD1
caldesmon 1
chr10_+_126630692 0.36 ENST00000359653.4
ZRANB1
zinc finger, RAN-binding domain containing 1
chr4_-_123377880 0.36 ENST00000226730.4
IL2
interleukin 2
chr5_-_146833222 0.36 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr16_+_1728257 0.36 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
HN1L
hematological and neurological expressed 1-like
chr5_-_35938674 0.36 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL
calcyphosine-like
chr1_+_12916941 0.35 ENST00000240189.2
PRAMEF2
PRAME family member 2
chr8_-_116504448 0.34 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr6_+_35996859 0.34 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chr7_-_14880892 0.34 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB
diacylglycerol kinase, beta 90kDa
chr1_-_154600421 0.33 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chr7_+_116165038 0.33 ENST00000393470.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr1_+_156338993 0.33 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr17_-_2996290 0.33 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr5_+_161495038 0.32 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr9_+_105757590 0.32 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr2_-_163008903 0.32 ENST00000418842.2
ENST00000375497.3
GCG
glucagon
chr3_-_155394152 0.32 ENST00000494598.1
PLCH1
phospholipase C, eta 1
chr16_+_1728305 0.32 ENST00000569765.1
HN1L
hematological and neurological expressed 1-like
chr9_-_110251836 0.31 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr10_-_69597915 0.31 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr11_+_114168773 0.31 ENST00000542647.1
ENST00000545255.1
NNMT
nicotinamide N-methyltransferase
chr1_-_204135450 0.31 ENST00000272190.8
ENST00000367195.2
REN
renin
chr4_+_169842707 0.30 ENST00000503290.1
PALLD
palladin, cytoskeletal associated protein
chr14_+_22520762 0.30 ENST00000390449.3
TRAV21
T cell receptor alpha variable 21
chr4_+_155484103 0.30 ENST00000302068.4
FGB
fibrinogen beta chain
chr19_-_1650666 0.30 ENST00000588136.1
TCF3
transcription factor 3
chr3_-_119396193 0.30 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17
COX17 cytochrome c oxidase copper chaperone
chr6_+_108977520 0.29 ENST00000540898.1
FOXO3
forkhead box O3
chr4_-_23735183 0.29 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr3_+_100354442 0.29 ENST00000475887.1
GPR128
G protein-coupled receptor 128
chr6_+_15401075 0.29 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr5_+_140800638 0.29 ENST00000398587.2
ENST00000518882.1
PCDHGA11
protocadherin gamma subfamily A, 11
chr6_-_136847610 0.29 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr14_+_22782867 0.28 ENST00000390467.3
TRAV40
T cell receptor alpha variable 40
chr10_+_97759848 0.28 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr10_+_111765562 0.28 ENST00000360162.3
ADD3
adducin 3 (gamma)
chrX_+_11129388 0.28 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
HCCS
holocytochrome c synthase
chr9_-_21166659 0.28 ENST00000380225.1
IFNA21
interferon, alpha 21
chr6_-_29055090 0.28 ENST00000377173.2
OR2B3
olfactory receptor, family 2, subfamily B, member 3
chrX_+_30261847 0.28 ENST00000378981.3
ENST00000397550.1
MAGEB1
melanoma antigen family B, 1
chr2_+_210517895 0.28 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr13_-_38172863 0.27 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr20_-_18477862 0.27 ENST00000337227.4
RBBP9
retinoblastoma binding protein 9
chr4_-_159080806 0.27 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr15_+_26360970 0.27 ENST00000556159.1
ENST00000557523.1
LINC00929
long intergenic non-protein coding RNA 929
chr4_-_47983519 0.27 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr6_-_136847099 0.27 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr6_+_42018614 0.26 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr13_-_33924755 0.26 ENST00000439831.1
ENST00000567873.1
STARD13
StAR-related lipid transfer (START) domain containing 13
chr15_+_42066632 0.26 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr3_+_171561127 0.25 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr3_+_35721106 0.25 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_46412345 0.25 ENST00000292303.4
CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr10_+_135207623 0.25 ENST00000317502.6
ENST00000432508.3
MTG1
mitochondrial ribosome-associated GTPase 1
chr18_+_616672 0.25 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr17_+_56315936 0.25 ENST00000543544.1
LPO
lactoperoxidase
chr5_+_121297650 0.25 ENST00000339397.4
SRFBP1
serum response factor binding protein 1
chr3_+_178276488 0.25 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr10_-_29811456 0.25 ENST00000535393.1
SVIL
supervillin
chr12_-_53601055 0.25 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
ITGB7
integrin, beta 7
chr4_-_122302163 0.25 ENST00000394427.2
QRFPR
pyroglutamylated RFamide peptide receptor
chr3_-_150421728 0.24 ENST00000295910.6
ENST00000491361.1
FAM194A
family with sequence similarity 194, member A
chr8_-_79470728 0.24 ENST00000522807.1
ENST00000519242.1
ENST00000522302.1
RP11-594N15.2
RP11-594N15.2
chr17_+_56315787 0.24 ENST00000262290.4
ENST00000421678.2
LPO
lactoperoxidase
chr10_-_69597810 0.24 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr2_+_233527443 0.24 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr10_+_135207598 0.24 ENST00000477902.2
MTG1
mitochondrial ribosome-associated GTPase 1
chr5_-_98262240 0.24 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr1_+_89829610 0.24 ENST00000370456.4
ENST00000535065.1
GBP6
guanylate binding protein family, member 6
chr4_-_76912070 0.24 ENST00000395711.4
ENST00000356260.5
SDAD1
SDA1 domain containing 1
chr2_+_166095898 0.24 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr17_-_2966901 0.24 ENST00000575751.1
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr1_-_226926864 0.24 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr10_-_74114714 0.24 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DNAJB12
DnaJ (Hsp40) homolog, subfamily B, member 12
chr6_-_49604545 0.23 ENST00000371175.4
ENST00000229810.7
RHAG
Rh-associated glycoprotein
chr4_-_48082192 0.23 ENST00000507351.1
TXK
TXK tyrosine kinase
chr10_-_28623368 0.23 ENST00000441595.2
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr2_-_175462456 0.23 ENST00000409891.1
ENST00000410117.1
WIPF1
WAS/WASL interacting protein family, member 1
chr5_+_167181917 0.23 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr16_-_15180257 0.23 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr4_+_70796784 0.23 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr3_-_99569821 0.23 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr10_+_91152303 0.22 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr15_-_56209306 0.22 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr3_-_119278446 0.22 ENST00000264246.3
CD80
CD80 molecule
chr17_-_39197699 0.22 ENST00000306271.4
KRTAP1-1
keratin associated protein 1-1
chr6_-_29424848 0.21 ENST00000377149.1
OR11A1
olfactory receptor, family 11, subfamily A, member 1
chr5_-_177207634 0.21 ENST00000513554.1
ENST00000440605.3
FAM153A
family with sequence similarity 153, member A
chr11_+_4788500 0.21 ENST00000380390.1
MMP26
matrix metallopeptidase 26
chr17_+_73452695 0.21 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
KIAA0195
KIAA0195
chr8_+_11666649 0.21 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr6_-_49681235 0.21 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chr13_+_32313658 0.21 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr8_-_19102999 0.21 ENST00000517949.1
RP11-1080G15.1
RP11-1080G15.1
chr4_-_119759795 0.21 ENST00000419654.2
SEC24D
SEC24 family member D
chr8_+_66933779 0.21 ENST00000276570.5
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chrX_+_103031758 0.21 ENST00000303958.2
ENST00000361621.2
PLP1
proteolipid protein 1
chr19_-_11545920 0.20 ENST00000356392.4
ENST00000591179.1
CCDC151
coiled-coil domain containing 151
chr8_-_101962777 0.20 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr9_-_16705069 0.20 ENST00000471301.2
BNC2
basonuclin 2
chr7_+_29519486 0.20 ENST00000409041.4
CHN2
chimerin 2
chr7_-_113559104 0.20 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr12_-_26278030 0.20 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr6_-_40555176 0.19 ENST00000338305.6
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr10_+_27793257 0.19 ENST00000375802.3
RAB18
RAB18, member RAS oncogene family
chr7_-_56174161 0.19 ENST00000395422.3
CHCHD2
coiled-coil-helix-coiled-coil-helix domain containing 2
chr6_+_27107053 0.19 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr2_+_169926047 0.19 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr4_+_15341442 0.19 ENST00000397700.2
ENST00000295297.4
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr10_+_96522361 0.19 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr7_-_14026063 0.19 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr1_+_50571949 0.19 ENST00000357083.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr19_+_3880581 0.19 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ATCAY
ataxia, cerebellar, Cayman type
chr12_-_87232644 0.19 ENST00000549405.2
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr5_+_141346385 0.19 ENST00000513019.1
ENST00000356143.1
RNF14
ring finger protein 14
chr14_+_67291158 0.19 ENST00000555456.1
GPHN
gephyrin
chr22_-_39268308 0.18 ENST00000407418.3
CBX6
chromobox homolog 6
chr2_+_185463093 0.18 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr6_+_63921399 0.18 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr18_-_57027194 0.18 ENST00000251047.5
LMAN1
lectin, mannose-binding, 1
chr3_+_130150307 0.18 ENST00000512836.1
COL6A5
collagen, type VI, alpha 5
chr4_+_70146217 0.18 ENST00000335568.5
ENST00000511240.1
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
chr6_+_27356497 0.18 ENST00000244576.4
ZNF391
zinc finger protein 391

Network of associatons between targets according to the STRING database.

First level regulatory network of CDC5L

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.7 2.0 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4 1.8 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.4 2.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.3 1.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 1.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 1.1 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.2 0.5 GO:0048627 myoblast development(GO:0048627)
0.1 0.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.4 GO:2000391 positive regulation of neutrophil extravasation(GO:2000391)
0.1 1.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.4 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.9 GO:0051414 response to cortisol(GO:0051414)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.3 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.9 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.1 0.3 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.2 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.4 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.9 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.6 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.3 GO:1990523 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.1 0.3 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018) response to cGMP(GO:0070305)
0.1 0.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.3 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0061346 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.5 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 1.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 1.2 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.7 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 3.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0033152 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.7 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.1 GO:0035990 tendon development(GO:0035989) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.5 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.4 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.0 1.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.1 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 1.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.5 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 1.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.5 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0051001 glycosylceramide catabolic process(GO:0046477) negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 1.0 GO:0035690 cellular response to drug(GO:0035690)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.2 2.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.0 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.3 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.0 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.6 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.6 GO:0000322 storage vacuole(GO:0000322)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.6 1.8 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.5 2.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3 1.1 GO:0016499 orexin receptor activity(GO:0016499)
0.3 1.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.9 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.3 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 1.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 1.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.3 GO:0031489 myosin V binding(GO:0031489)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.2 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 0.3 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 0.5 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.3 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.4 GO:0043208 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 1.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.3 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 4.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 6.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.6 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation