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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CDX1

Z-value: 0.69

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Transcription factors associated with CDX1

Gene Symbol Gene ID Gene Info
CDX1
ENSG00000113722.12 caudal type homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDX1hg19_v2_chr5_+_149546334_149546364-0.222.9e-01Click!

Activity profile of CDX1 motif

Sorted Z-values of CDX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_52779433 3.00 ENST00000257951.3
KRT84
keratin 84
chr16_-_18887627 1.16 ENST00000563235.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr7_+_79765071 0.80 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr12_+_8995832 0.68 ENST00000541459.1
A2ML1
alpha-2-macroglobulin-like 1
chr12_-_9268707 0.60 ENST00000318602.7
A2M
alpha-2-macroglobulin
chr11_+_7618413 0.60 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_47489240 0.58 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr14_+_65878565 0.56 ENST00000556518.1
ENST00000557164.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr6_+_116832789 0.56 ENST00000368599.3
FAM26E
family with sequence similarity 26, member E
chr12_+_19358228 0.50 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr5_+_61874562 0.49 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr4_-_186732048 0.49 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr9_+_124103625 0.49 ENST00000594963.1
AL161784.1
Uncharacterized protein
chr1_+_84630053 0.48 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_+_80730292 0.48 ENST00000298820.3
OTOGL
otogelin-like
chr5_-_111093759 0.47 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr6_+_143999072 0.47 ENST00000440869.2
ENST00000367582.3
ENST00000451827.2
PHACTR2
phosphatase and actin regulator 2
chr20_-_17539456 0.47 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr9_-_3469181 0.45 ENST00000366116.2
AL365202.1
Uncharacterized protein
chrX_+_130192318 0.44 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr1_+_84630645 0.44 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_-_63995871 0.44 ENST00000315289.2
RTKN2
rhotekin 2
chr5_-_55412774 0.43 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr21_+_31768348 0.43 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr3_-_168865522 0.41 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr9_-_21228221 0.41 ENST00000413767.2
IFNA17
interferon, alpha 17
chr11_+_28129795 0.39 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr9_-_21305312 0.38 ENST00000259555.4
IFNA5
interferon, alpha 5
chr1_+_89246647 0.37 ENST00000544045.1
PKN2
protein kinase N2
chr3_-_108672742 0.37 ENST00000261047.3
GUCA1C
guanylate cyclase activator 1C
chr22_+_25595817 0.37 ENST00000215855.2
ENST00000404334.1
CRYBB3
crystallin, beta B3
chr3_-_108672609 0.37 ENST00000393963.3
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr3_-_149095652 0.37 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr6_+_132455118 0.36 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr12_+_58013693 0.35 ENST00000320442.4
ENST00000379218.2
SLC26A10
solute carrier family 26, member 10
chr11_-_89224508 0.35 ENST00000525196.1
NOX4
NADPH oxidase 4
chr19_+_35417798 0.34 ENST00000303586.7
ENST00000439785.1
ENST00000601540.1
ZNF30
zinc finger protein 30
chr9_-_97356075 0.33 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr2_+_132479948 0.33 ENST00000355171.4
C2orf27A
chromosome 2 open reading frame 27A
chr2_-_165424973 0.32 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr13_+_53030107 0.32 ENST00000490903.1
ENST00000480747.1
CKAP2
cytoskeleton associated protein 2
chr17_-_67057114 0.32 ENST00000370732.2
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr3_+_190333097 0.32 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chr1_+_223101757 0.32 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr18_-_29264467 0.31 ENST00000383131.3
ENST00000237019.7
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr7_+_74188309 0.31 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr18_-_29264669 0.31 ENST00000306851.5
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr17_-_57229155 0.30 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr3_+_158787041 0.30 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr16_+_53241854 0.30 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr2_+_33359687 0.30 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr7_-_11871815 0.29 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr10_+_127661942 0.29 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr2_+_33359646 0.29 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr2_-_177502254 0.28 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chr11_-_89224638 0.28 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr14_-_54955721 0.28 ENST00000554908.1
GMFB
glia maturation factor, beta
chr3_+_107318157 0.27 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr7_+_138943265 0.27 ENST00000483726.1
UBN2
ubinuclein 2
chr12_+_32655048 0.27 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr10_-_95360983 0.27 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr17_-_48943706 0.26 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr1_+_178694300 0.26 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr4_-_22444733 0.26 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chrM_-_14670 0.26 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr11_-_51412448 0.26 ENST00000319760.6
OR4A5
olfactory receptor, family 4, subfamily A, member 5
chr1_+_178310581 0.25 ENST00000462775.1
RASAL2
RAS protein activator like 2
chr6_-_134373732 0.25 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr16_+_2014993 0.24 ENST00000564014.1
SNHG9
small nucleolar RNA host gene 9 (non-protein coding)
chr18_-_19994830 0.24 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr12_-_111358372 0.24 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr16_+_81272287 0.24 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr14_+_75179840 0.24 ENST00000554590.1
ENST00000341162.4
ENST00000534938.2
ENST00000553615.1
FCF1
FCF1 rRNA-processing protein
chr6_-_112575912 0.24 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr5_+_174905398 0.24 ENST00000321442.5
SFXN1
sideroflexin 1
chr9_+_77230499 0.24 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr2_-_151344172 0.23 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr12_-_31744031 0.23 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr2_+_170366203 0.23 ENST00000284669.1
KLHL41
kelch-like family member 41
chr9_+_124088860 0.23 ENST00000373806.1
GSN
gelsolin
chr17_-_67057047 0.23 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr6_-_110011704 0.22 ENST00000448084.2
AK9
adenylate kinase 9
chr2_-_89521942 0.22 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr11_-_2158507 0.22 ENST00000381392.1
ENST00000381395.1
ENST00000418738.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr12_-_90049878 0.22 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr2_-_183106641 0.22 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr7_+_32535060 0.21 ENST00000318709.4
ENST00000409301.1
ENST00000404479.1
AVL9
AVL9 homolog (S. cerevisiase)
chr11_+_133938820 0.21 ENST00000299106.4
ENST00000529443.2
JAM3
junctional adhesion molecule 3
chr14_+_53196872 0.21 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr1_+_15986364 0.21 ENST00000345034.1
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr5_-_138775177 0.21 ENST00000302060.5
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr1_-_68299130 0.21 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr1_+_28764653 0.21 ENST00000373836.3
PHACTR4
phosphatase and actin regulator 4
chr18_+_3466248 0.21 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr4_-_110723194 0.21 ENST00000394635.3
CFI
complement factor I
chr20_+_46130619 0.21 ENST00000372004.3
NCOA3
nuclear receptor coactivator 3
chr3_+_45636219 0.20 ENST00000273317.4
LIMD1
LIM domains containing 1
chr4_+_170581213 0.20 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr2_+_136343820 0.20 ENST00000410054.1
R3HDM1
R3H domain containing 1
chr20_+_46130671 0.20 ENST00000371998.3
ENST00000371997.3
NCOA3
nuclear receptor coactivator 3
chr6_-_112575838 0.20 ENST00000455073.1
LAMA4
laminin, alpha 4
chr13_-_33780133 0.20 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr18_-_53303123 0.19 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr16_+_66586461 0.19 ENST00000264001.4
ENST00000351137.4
ENST00000345436.4
ENST00000362093.4
ENST00000417030.2
ENST00000527729.1
ENST00000532838.1
CKLF
CKLF-CMTM1
chemokine-like factor
CKLF-CMTM1 readthrough
chr12_-_118628350 0.19 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr5_+_108083517 0.19 ENST00000281092.4
ENST00000536402.1
FER
fer (fps/fes related) tyrosine kinase
chr3_-_49055991 0.18 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
DALRD3
DALR anticodon binding domain containing 3
chrX_-_99987088 0.18 ENST00000372981.1
ENST00000263033.5
SYTL4
synaptotagmin-like 4
chr12_+_9144626 0.18 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr20_+_30795664 0.18 ENST00000375749.3
ENST00000375730.3
ENST00000539210.1
POFUT1
protein O-fucosyltransferase 1
chr18_-_31802282 0.18 ENST00000535475.1
NOL4
nucleolar protein 4
chr8_+_107738240 0.18 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr18_+_61445007 0.18 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr3_-_157221128 0.18 ENST00000392833.2
ENST00000362010.2
VEPH1
ventricular zone expressed PH domain-containing 1
chr15_-_56535464 0.18 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
RFX7
regulatory factor X, 7
chr14_-_81425828 0.18 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr7_+_141490017 0.17 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr18_-_31802056 0.17 ENST00000538587.1
NOL4
nucleolar protein 4
chr14_-_106518922 0.17 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr12_-_90049828 0.17 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chrX_+_129473916 0.17 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr8_+_22422749 0.17 ENST00000523900.1
SORBS3
sorbin and SH3 domain containing 3
chr13_+_49684445 0.17 ENST00000398316.3
FNDC3A
fibronectin type III domain containing 3A
chr8_+_1993173 0.17 ENST00000523438.1
MYOM2
myomesin 2
chr12_+_51318513 0.17 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr15_+_55700741 0.17 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr18_-_712618 0.17 ENST00000583771.1
ENST00000383578.3
ENST00000251101.7
ENOSF1
enolase superfamily member 1
chr14_+_96722152 0.17 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr3_-_196242233 0.17 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr5_-_78281603 0.17 ENST00000264914.4
ARSB
arylsulfatase B
chr5_+_140579162 0.17 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chr6_+_125304502 0.16 ENST00000519799.1
ENST00000368414.2
ENST00000359704.2
RNF217
ring finger protein 217
chr4_-_175205407 0.16 ENST00000393674.2
FBXO8
F-box protein 8
chr3_-_100712352 0.16 ENST00000471714.1
ENST00000284322.5
ABI3BP
ABI family, member 3 (NESH) binding protein
chr4_-_110723335 0.16 ENST00000394634.2
CFI
complement factor I
chr5_-_150138061 0.16 ENST00000521533.1
ENST00000424236.1
DCTN4
dynactin 4 (p62)
chr4_+_154073469 0.16 ENST00000441616.1
TRIM2
tripartite motif containing 2
chr2_+_143886877 0.16 ENST00000295095.6
ARHGAP15
Rho GTPase activating protein 15
chr6_-_110011718 0.16 ENST00000532976.1
AK9
adenylate kinase 9
chr1_+_150337144 0.16 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr8_+_1993152 0.16 ENST00000262113.4
MYOM2
myomesin 2
chr13_+_28519343 0.16 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr12_-_9760482 0.16 ENST00000229402.3
KLRB1
killer cell lectin-like receptor subfamily B, member 1
chrX_-_50386648 0.16 ENST00000460112.3
SHROOM4
shroom family member 4
chr21_+_17909594 0.16 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chrX_+_107288197 0.15 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr10_+_112327425 0.15 ENST00000361804.4
SMC3
structural maintenance of chromosomes 3
chr17_-_53809473 0.15 ENST00000575734.1
TMEM100
transmembrane protein 100
chr12_+_72079842 0.15 ENST00000266673.5
ENST00000550524.1
TMEM19
transmembrane protein 19
chr1_+_150337100 0.15 ENST00000401000.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chrX_+_107288239 0.15 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr7_+_105172532 0.15 ENST00000257700.2
RINT1
RAD50 interactor 1
chr8_+_37963011 0.15 ENST00000250635.7
ENST00000517719.1
ENST00000545394.1
ASH2L
ash2 (absent, small, or homeotic)-like (Drosophila)
chr5_-_122759032 0.15 ENST00000510582.3
ENST00000328236.5
ENST00000306481.6
ENST00000508442.2
ENST00000395431.2
CEP120
centrosomal protein 120kDa
chr8_+_93895865 0.15 ENST00000391681.1
AC117834.1
AC117834.1
chr14_-_67878917 0.15 ENST00000216446.4
PLEK2
pleckstrin 2
chr17_-_46690839 0.14 ENST00000498634.2
HOXB8
homeobox B8
chr4_-_110723134 0.14 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr8_+_104831554 0.14 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr17_-_55911970 0.14 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
RP11-60A24.3
chr1_+_81771806 0.13 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr3_-_183273477 0.13 ENST00000341319.3
KLHL6
kelch-like family member 6
chr6_-_15548591 0.13 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr4_-_152149033 0.13 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr4_+_86749045 0.13 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr5_+_140165876 0.13 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr3_-_139199565 0.13 ENST00000511956.1
RBP2
retinol binding protein 2, cellular
chr14_-_31926623 0.13 ENST00000356180.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr5_+_140602904 0.13 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr5_+_140792614 0.12 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chr4_+_69313145 0.12 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr5_-_75008244 0.12 ENST00000510798.1
ENST00000446329.2
POC5
POC5 centriolar protein
chr19_+_9296279 0.12 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr7_+_90012986 0.12 ENST00000416322.1
CLDN12
claudin 12
chr13_+_73302047 0.12 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
BORA
bora, aurora kinase A activator
chr2_-_112614424 0.12 ENST00000427997.1
ANAPC1
anaphase promoting complex subunit 1
chr1_+_89829610 0.12 ENST00000370456.4
ENST00000535065.1
GBP6
guanylate binding protein family, member 6
chr5_+_140571902 0.12 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr15_-_55700522 0.11 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chrX_-_148571884 0.11 ENST00000537071.1
IDS
iduronate 2-sulfatase
chr15_-_83474806 0.11 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr1_+_92545862 0.11 ENST00000370382.3
ENST00000342818.3
BTBD8
BTB (POZ) domain containing 8
chr10_-_126480381 0.11 ENST00000368836.2
METTL10
methyltransferase like 10
chr7_+_77469439 0.11 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr22_-_37213554 0.11 ENST00000443735.1
PVALB
parvalbumin
chrX_+_37639264 0.11 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr8_-_95220775 0.11 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr8_+_7693993 0.11 ENST00000314265.2
DEFB104A
defensin, beta 104A
chr11_-_4629388 0.11 ENST00000526337.1
ENST00000300747.5
TRIM68
tripartite motif containing 68
chrX_-_122756660 0.11 ENST00000441692.1
THOC2
THO complex 2
chr15_-_55700457 0.11 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1
cell cycle progression 1
chr7_-_143454789 0.11 ENST00000470691.2
CTAGE6
CTAGE family, member 6
chr6_-_117150198 0.11 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr1_+_12290121 0.10 ENST00000358136.3
ENST00000356315.4
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr4_+_86748898 0.10 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr14_+_39703112 0.10 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr14_+_102276209 0.10 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr22_+_40322595 0.10 ENST00000420971.1
ENST00000544756.1
GRAP2
GRB2-related adaptor protein 2
chr10_-_126716459 0.10 ENST00000309035.6
CTBP2
C-terminal binding protein 2
chr11_-_7818520 0.10 ENST00000329434.2
OR5P2
olfactory receptor, family 5, subfamily P, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 GO:0035878 nail development(GO:0035878)
0.2 0.6 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.9 GO:0097338 response to clozapine(GO:0097338)
0.1 0.4 GO:0006756 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.5 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.3 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.2 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.8 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.2 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.1 0.4 GO:0035624 receptor transactivation(GO:0035624)
0.1 0.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.2 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.3 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.0 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.3 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:1903626 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.6 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.0 GO:0072019 isoleucine catabolic process(GO:0006550) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.5 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:0051684 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.0 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.0 GO:0071418 cellular response to amine stimulus(GO:0071418)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 2.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.0 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0019959 interleukin-8 binding(GO:0019959)
0.2 3.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 0.6 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.5 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.6 GO:0050436 microfibril binding(GO:0050436)
0.1 0.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.6 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.3 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 1.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.4 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.6 GO:0016918 retinal binding(GO:0016918)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 1.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.0 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.9 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases