ISMARA results: CDX2

Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation

Downloads

Results for CDX2

Z-value: 0.46

Motif logo

Transcription factors associated with CDX2

Gene Symbol	Gene ID	Gene Info
CDX2 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000165556.9	caudal type homeobox 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CDX2	hg19_v2_chr13_-_28545276_28545276	-0.35	8.2e-02	Click!

Activity profile of CDX2 motif

Sorted Z-values of CDX2 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_-_72649763 Show fit	0.52	ENST00000513476.1	GC Ensembl NCBI GeneCards UniProt NextProt Show fit	group-specific component (vitamin D binding protein)
chr7_-_41742697 Show fit	0.47	ENST00000242208.4	INHBA Ensembl NCBI GeneCards UniProt NextProt Show fit	inhibin, beta A
chr13_+_108922228 Show fit	0.46	ENST00000542136.1	TNFSF13B Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor (ligand) superfamily, member 13b
chr7_+_141811539 Show fit	0.39	ENST00000550469.2 ENST00000477922.3	RP11-1220K2.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	Putative inactive maltase-glucoamylase-like protein LOC93432
chr17_-_46690839 Show fit	0.39	ENST00000498634.2	HOXB8 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox B8
chr8_+_124084899 Show fit	0.36	ENST00000287380.1 ENST00000309336.3 ENST00000519418.1 ENST00000327098.5 ENST00000522420.1 ENST00000521676.1 ENST00000378080.2	TBC1D31 Ensembl NCBI GeneCards UniProt NextProt Show fit	TBC1 domain family, member 31
chr6_+_32812568 Show fit	0.30	ENST00000414474.1	PSMB9 Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 9
chr4_-_76957214 Show fit	0.29	ENST00000306621.3	CXCL11 Ensembl NCBI GeneCards UniProt NextProt Show fit	chemokine (C-X-C motif) ligand 11
chr4_-_169239921 Show fit	0.29	ENST00000514995.1 ENST00000393743.3	DDX60 Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr1_-_7913089 Show fit	0.29	ENST00000361696.5	UTS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	urotensin 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0002636	positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0	0.6	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.2	0.5	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0	0.5	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.5	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.4	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.4	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.4	GO:0021516	dorsal spinal cord development(GO:0021516)
0.1	0.3	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1	0.3	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)

Showing 1 to 10 of 38 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.2	0.5	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0	0.4	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.3	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.3	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.2	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	0.1	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)

Showing 1 to 10 of 14 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0032089	NACHT domain binding(GO:0032089)
0.2	0.5	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	0.5	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.5	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.4	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	0.4	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1	0.3	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.1	0.3	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.3	GO:0005412	glucose:sodium symporter activity(GO:0005412)

Showing 1 to 10 of 30 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.4	PID CONE PATHWAY	Visual signal transduction: Cones

Showing 1 to 2 of 2 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Total log-likelihood	Term	Description
0.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors

Showing 1 to 4 of 4 entries

Results for CDX2

Z-value: 0.46

Motif logo

Transcription factors associated with CDX2

Activity-expression correlation:

Activity profile of CDX2 motif

Sorted Z-values of CDX2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX2

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: