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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CEBPA

Z-value: 0.99

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Transcription factors associated with CEBPA

Gene Symbol Gene ID Gene Info
ENSG00000245848.2 CCAAT enhancer binding protein alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPAhg19_v2_chr19_-_33793430_33793470-0.272.0e-01Click!

Activity profile of CEBPA motif

Sorted Z-values of CEBPA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102668879 9.57 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr6_+_127898312 5.97 ENST00000329722.7
chromosome 6 open reading frame 58
chr1_+_101185290 4.88 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
vascular cell adhesion molecule 1
chr1_-_173020056 4.33 ENST00000239468.2
ENST00000404377.3
tumor necrosis factor (ligand) superfamily, member 18
chr21_+_43619796 3.57 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr21_+_34775181 3.51 ENST00000290219.6
interferon gamma receptor 2 (interferon gamma transducer 1)
chr2_+_102721023 3.46 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr4_+_74606223 3.24 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr1_-_89531041 3.23 ENST00000370473.4
guanylate binding protein 1, interferon-inducible
chr1_-_173176452 3.15 ENST00000281834.3
tumor necrosis factor (ligand) superfamily, member 4
chr1_+_169079823 2.98 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_+_125758865 2.79 ENST00000542322.1
ENST00000544396.1
GRAM domain containing 3
chr5_+_125758813 2.73 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chr21_-_37852359 2.46 ENST00000399137.1
ENST00000399135.1
claudin 14
chr18_+_61554932 2.40 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr5_-_121413974 2.40 ENST00000231004.4
lysyl oxidase
chr4_-_139163491 2.37 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr4_-_681114 2.34 ENST00000503156.1
major facilitator superfamily domain containing 7
chr2_+_228678550 2.33 ENST00000409189.3
ENST00000358813.4
chemokine (C-C motif) ligand 20
chr6_+_126240442 2.32 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
nuclear receptor coactivator 7
chr15_-_80263506 2.25 ENST00000335661.6
BCL2-related protein A1
chr6_+_126102292 2.22 ENST00000368357.3
nuclear receptor coactivator 7
chr7_-_92777606 2.14 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr11_-_104905840 2.01 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr1_+_165797024 1.82 ENST00000372212.4
uridine-cytidine kinase 2
chr3_-_158450231 1.79 ENST00000479756.1
retinoic acid receptor responder (tazarotene induced) 1
chr4_-_185747188 1.76 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
acyl-CoA synthetase long-chain family member 1
chr12_+_21207503 1.72 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr3_-_4793274 1.64 ENST00000414938.1
eosinophil granule ontogeny transcript (non-protein coding)
chr3_-_107777208 1.60 ENST00000398258.3
CD47 molecule
chr3_-_123339343 1.50 ENST00000578202.1
myosin light chain kinase
chr3_-_123339418 1.49 ENST00000583087.1
myosin light chain kinase
chr7_+_18535786 1.45 ENST00000406072.1
histone deacetylase 9
chr2_+_103035102 1.45 ENST00000264260.2
interleukin 18 receptor accessory protein
chrX_-_68385354 1.37 ENST00000361478.1
praja ring finger 1, E3 ubiquitin protein ligase
chrX_-_68385274 1.33 ENST00000374584.3
ENST00000590146.1
praja ring finger 1, E3 ubiquitin protein ligase
chr5_-_150473127 1.33 ENST00000521001.1
TNFAIP3 interacting protein 1
chr6_+_31895467 1.31 ENST00000556679.1
ENST00000456570.1
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_-_156721502 1.30 ENST00000357325.5
hepatoma-derived growth factor
chr2_-_152146385 1.27 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr12_+_72058130 1.27 ENST00000547843.1
THAP domain containing, apoptosis associated protein 2
chr15_+_71228826 1.26 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
leucine rich repeat containing 49
chr3_+_105086056 1.23 ENST00000472644.2
activated leukocyte cell adhesion molecule
chr3_+_105085734 1.18 ENST00000306107.5
activated leukocyte cell adhesion molecule
chr1_+_165864800 1.13 ENST00000469256.2
uridine-cytidine kinase 2
chr5_-_16742330 1.13 ENST00000505695.1
ENST00000427430.2
myosin X
chr3_-_112693865 1.11 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200 receptor 1
chr12_+_75874580 1.09 ENST00000456650.3
GLI pathogenesis-related 1
chr1_-_203198790 1.08 ENST00000367229.1
ENST00000255427.3
ENST00000535569.1
chitinase 1 (chitotriosidase)
chr21_+_35736302 1.08 ENST00000290310.3
potassium voltage-gated channel, Isk-related family, member 2
chr10_+_114133773 1.06 ENST00000354655.4
acyl-CoA synthetase long-chain family member 5
chr3_-_112218378 1.05 ENST00000334529.5
B and T lymphocyte associated
chr11_-_104972158 1.03 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr2_+_143635067 1.02 ENST00000264170.4
kynureninase
chr12_+_21168630 1.01 ENST00000421593.2
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr17_+_20059302 0.99 ENST00000395530.2
sperm antigen with calponin homology and coiled-coil domains 1
chr7_+_26191809 0.98 ENST00000056233.3
nuclear factor, erythroid 2-like 3
chr5_+_149980622 0.97 ENST00000394243.1
synaptopodin
chr1_-_200992827 0.95 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr14_+_51955831 0.95 ENST00000356218.4
FERM domain containing 6
chr4_-_69536346 0.94 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chr19_-_56249740 0.93 ENST00000590200.1
ENST00000332836.2
NLR family, pyrin domain containing 9
chr8_+_38585704 0.91 ENST00000519416.1
ENST00000520615.1
transforming, acidic coiled-coil containing protein 1
chr9_+_132934835 0.90 ENST00000372398.3
neuronal calcium sensor 1
chr3_-_112218205 0.89 ENST00000383680.4
B and T lymphocyte associated
chr14_+_52164820 0.88 ENST00000554167.1
FERM domain containing 6
chr18_-_61311485 0.87 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr19_-_4540486 0.86 ENST00000306390.6
leucine-rich alpha-2-glycoprotein 1
chr6_-_43496605 0.84 ENST00000455285.2
exportin 5
chr6_+_150920999 0.82 ENST00000367328.1
ENST00000367326.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr4_-_153274078 0.80 ENST00000263981.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_+_110082487 0.79 ENST00000527748.1
G protein-coupled receptor 61
chr8_+_38586068 0.79 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
transforming, acidic coiled-coil containing protein 1
chr7_+_30634297 0.79 ENST00000389266.3
glycyl-tRNA synthetase
chr16_+_56969284 0.79 ENST00000568358.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr3_-_71632894 0.78 ENST00000493089.1
forkhead box P1
chr12_-_10251539 0.78 ENST00000420265.2
C-type lectin domain family 1, member A
chr11_-_85397167 0.77 ENST00000316398.3
coiled-coil domain containing 89
chr19_+_45147313 0.77 ENST00000406449.4
poliovirus receptor
chr6_-_11779014 0.75 ENST00000229583.5
androgen-dependent TFPI-regulating protein
chr15_-_89878025 0.75 ENST00000268124.5
ENST00000442287.2
polymerase (DNA directed), gamma
chr16_+_56485402 0.73 ENST00000566157.1
ENST00000562150.1
ENST00000561646.1
ENST00000568397.1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr12_-_323689 0.71 ENST00000428720.1
solute carrier family 6 (neurotransmitter transporter), member 12
chr17_-_67264947 0.71 ENST00000586811.1
ATP-binding cassette, sub-family A (ABC1), member 5
chr12_-_10251603 0.70 ENST00000457018.2
C-type lectin domain family 1, member A
chr17_+_20059358 0.70 ENST00000536879.1
ENST00000395522.2
ENST00000395525.3
sperm antigen with calponin homology and coiled-coil domains 1
chr1_+_196743912 0.69 ENST00000367425.4
complement factor H-related 3
chr5_-_160279207 0.69 ENST00000327245.5
ATPase, class V, type 10B
chr10_-_45474237 0.69 ENST00000448778.1
ENST00000298295.3
chromosome 10 open reading frame 10
chr3_-_66551351 0.68 ENST00000273261.3
leucine-rich repeats and immunoglobulin-like domains 1
chr6_+_106534192 0.68 ENST00000369091.2
ENST00000369096.4
PR domain containing 1, with ZNF domain
chr7_+_129932974 0.67 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
carboxypeptidase A4
chr1_+_159409512 0.67 ENST00000423932.3
olfactory receptor, family 10, subfamily J, member 1
chr19_+_55014085 0.66 ENST00000351841.2
leukocyte-associated immunoglobulin-like receptor 2
chr6_+_12717892 0.66 ENST00000379350.1
phosphatase and actin regulator 1
chr20_+_58630972 0.65 ENST00000313426.1
chromosome 20 open reading frame 197
chr1_+_171154347 0.65 ENST00000209929.7
ENST00000441535.1
flavin containing monooxygenase 2 (non-functional)
chr1_+_107682629 0.65 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
netrin G1
chr8_+_145064215 0.65 ENST00000313269.5
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr12_-_10251576 0.63 ENST00000315330.4
C-type lectin domain family 1, member A
chr19_+_55014013 0.63 ENST00000301202.2
leukocyte-associated immunoglobulin-like receptor 2
chr12_+_75874460 0.63 ENST00000266659.3
GLI pathogenesis-related 1
chr18_-_5396271 0.62 ENST00000579951.1
erythrocyte membrane protein band 4.1-like 3
chr3_-_191000172 0.62 ENST00000427544.2
urotensin 2B
chr17_+_21191341 0.61 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
mitogen-activated protein kinase kinase 3
chr1_+_196743943 0.61 ENST00000471440.2
ENST00000391985.3
complement factor H-related 3
chr3_-_66551397 0.61 ENST00000383703.3
leucine-rich repeats and immunoglobulin-like domains 1
chr15_-_70387120 0.60 ENST00000539550.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr11_+_86667117 0.60 ENST00000531827.1
RP11-736K20.6
chr5_+_49962772 0.59 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
poly (ADP-ribose) polymerase family, member 8
chr8_+_18248786 0.59 ENST00000520116.1
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr17_-_60883993 0.58 ENST00000583803.1
ENST00000456609.2
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr19_+_33865218 0.58 ENST00000585933.2
CCAAT/enhancer binding protein (C/EBP), gamma
chr1_-_159684371 0.57 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
C-reactive protein, pentraxin-related
chr19_+_6887571 0.57 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
egf-like module containing, mucin-like, hormone receptor-like 1
chr2_-_89545079 0.57 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr22_+_35776828 0.56 ENST00000216117.8
heme oxygenase (decycling) 1
chr19_-_49496557 0.55 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
glycogen synthase 1 (muscle)
chr6_+_29910301 0.55 ENST00000376809.5
ENST00000376802.2
major histocompatibility complex, class I, A
chr8_+_18248755 0.54 ENST00000286479.3
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr9_-_117568365 0.54 ENST00000374045.4
tumor necrosis factor (ligand) superfamily, member 15
chr16_+_56970567 0.53 ENST00000563911.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr16_+_23765948 0.53 ENST00000300113.2
calcineurin-like EF-hand protein 2
chr5_+_170736243 0.52 ENST00000296921.5
T-cell leukemia homeobox 3
chr1_+_248201474 0.52 ENST00000366479.2
olfactory receptor, family 2, subfamily L, member 2
chr2_+_143635222 0.52 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
kynureninase
chr16_-_2059797 0.52 ENST00000563630.1
zinc finger protein 598
chr2_-_228497888 0.52 ENST00000264387.4
ENST00000409066.1
chromosome 2 open reading frame 83
chr19_+_45394477 0.52 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr10_-_27444143 0.51 ENST00000477432.1
YME1-like 1 ATPase
chr2_+_42104692 0.51 ENST00000398796.2
ENST00000442214.1
AC104654.1
chr11_-_119187826 0.51 ENST00000264036.4
melanoma cell adhesion molecule
chr19_-_48389651 0.50 ENST00000222002.3
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr1_-_193075180 0.50 ENST00000367440.3
glutaredoxin 2
chr5_-_145483932 0.50 ENST00000311450.4
PLAC8-like 1
chr3_+_75955817 0.50 ENST00000487694.3
ENST00000602589.1
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr6_+_30457244 0.50 ENST00000376630.4
major histocompatibility complex, class I, E
chrX_+_15767971 0.49 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chrX_+_16141667 0.49 ENST00000380289.2
gastrin-releasing peptide receptor
chr17_-_60142609 0.49 ENST00000397786.2
mediator complex subunit 13
chr20_+_46130671 0.49 ENST00000371998.3
ENST00000371997.3
nuclear receptor coactivator 3
chr1_-_207095324 0.48 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr19_-_15442701 0.48 ENST00000594841.1
ENST00000601941.1
bromodomain containing 4
chr4_+_37962018 0.48 ENST00000504686.1
pituitary tumor-transforming 2
chr5_+_95998070 0.48 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
calpastatin
chr7_-_138482933 0.47 ENST00000310018.2
ATPase, H+ transporting, lysosomal V0 subunit a4
chr14_+_22554680 0.47 ENST00000390451.2
T cell receptor alpha variable 23/delta variable 6
chr17_-_6983550 0.47 ENST00000576617.1
ENST00000416562.2
C-type lectin domain family 10, member A
chrX_+_139791917 0.47 ENST00000607004.1
ENST00000370535.3
long intergenic non-protein coding RNA 632
chr19_+_48949030 0.44 ENST00000253237.5
glutamate-rich WD repeat containing 1
chr7_-_138482849 0.44 ENST00000353492.4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr1_+_75594119 0.44 ENST00000294638.5
LIM homeobox 8
chr17_+_21030260 0.44 ENST00000579303.1
dehydrogenase/reductase (SDR family) member 7B
chr7_-_14026063 0.43 ENST00000443608.1
ENST00000438956.1
ets variant 1
chr5_+_156696362 0.43 ENST00000377576.3
cytoplasmic FMR1 interacting protein 2
chr17_-_6983594 0.43 ENST00000571664.1
ENST00000254868.4
C-type lectin domain family 10, member A
chr12_-_71551652 0.42 ENST00000546561.1
tetraspanin 8
chr4_+_184020398 0.42 ENST00000403733.3
ENST00000378925.3
WW and C2 domain containing 2
chr20_+_46130601 0.42 ENST00000341724.6
nuclear receptor coactivator 3
chr2_-_239140276 0.42 ENST00000334973.4
Protein LOC151174
chr7_-_32111009 0.42 ENST00000396184.3
ENST00000396189.2
ENST00000321453.7
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr12_+_88429223 0.42 ENST00000356891.3
chromosome 12 open reading frame 29
chr10_-_70092635 0.41 ENST00000309049.4
phenazine biosynthesis-like protein domain containing
chrX_+_153448107 0.41 ENST00000369935.5
opsin 1 (cone pigments), medium-wave-sensitive
chr17_-_62658186 0.41 ENST00000262435.9
SMAD specific E3 ubiquitin protein ligase 2
chr16_+_56965960 0.41 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr21_-_46348694 0.41 ENST00000355153.4
ENST00000397850.2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_1711508 0.41 ENST00000378625.1
NAD kinase
chr12_-_53074182 0.40 ENST00000252244.3
keratin 1
chr11_-_10590238 0.40 ENST00000256178.3
lymphatic vessel endothelial hyaluronan receptor 1
chr5_+_95997769 0.40 ENST00000338252.3
ENST00000508830.1
calpastatin
chr16_+_7382745 0.40 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_153321301 0.39 ENST00000368739.3
peptidoglycan recognition protein 4
chr3_-_46249878 0.39 ENST00000296140.3
chemokine (C-C motif) receptor 1
chr4_-_70826725 0.39 ENST00000353151.3
casein beta
chr3_+_46395219 0.39 ENST00000445132.2
ENST00000292301.4
chemokine (C-C motif) receptor 2
chr2_-_31637560 0.39 ENST00000379416.3
xanthine dehydrogenase
chr5_-_137878887 0.39 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
eukaryotic translation termination factor 1
chr1_-_180991978 0.39 ENST00000542060.1
ENST00000258301.5
syntaxin 6
chr10_-_61900762 0.39 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chr2_+_90060377 0.38 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr10_-_79789291 0.38 ENST00000372371.3
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr11_-_10590118 0.38 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chrX_+_125953746 0.38 ENST00000371125.3
chromosome X open reading frame 64
chr1_-_207095212 0.38 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr4_-_103746924 0.38 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
ubiquitin-conjugating enzyme E2D 3
chr12_+_41831485 0.37 ENST00000539469.2
ENST00000298919.7
PDZ domain containing ring finger 4
chr15_-_64648273 0.37 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
casein kinase 1, gamma 1
chr3_+_157154578 0.37 ENST00000295927.3
pentraxin 3, long
chr12_-_62586543 0.37 ENST00000416284.3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr16_-_2059748 0.37 ENST00000562103.1
ENST00000431526.1
zinc finger protein 598
chr14_+_95078714 0.37 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr10_+_114710516 0.36 ENST00000542695.1
ENST00000346198.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr11_+_60050026 0.36 ENST00000395016.3
membrane-spanning 4-domains, subfamily A, member 4A
chr7_+_117251671 0.36 ENST00000468795.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr4_-_48136217 0.36 ENST00000264316.4
TXK tyrosine kinase
chr1_-_8939265 0.36 ENST00000489867.1
enolase 1, (alpha)
chr16_+_2587965 0.36 ENST00000342085.4
ENST00000566659.1
3-phosphoinositide dependent protein kinase-1
chr5_-_132113559 0.36 ENST00000448933.1
septin 8
chr5_+_169010638 0.36 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
spindle apparatus coiled-coil protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
1.1 4.3 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
1.1 3.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.1 3.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.9 5.4 GO:0032730 positive regulation of interleukin-1 alpha production(GO:0032730)
0.9 3.6 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.7 2.9 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.7 4.9 GO:0022614 membrane to membrane docking(GO:0022614)
0.6 3.0 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.5 1.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.5 1.4 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.4 1.4 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.3 3.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.3 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 1.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.3 1.8 GO:0003383 apical constriction(GO:0003383)
0.3 0.8 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.3 1.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 0.8 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.3 9.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.2 1.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 4.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 0.9 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 1.8 GO:0034201 response to oleic acid(GO:0034201)
0.2 1.2 GO:0035624 receptor transactivation(GO:0035624)
0.2 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 0.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.8 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.2 0.6 GO:0014806 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.2 2.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.8 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 0.8 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 0.8 GO:1901256 interleukin-21 production(GO:0032625) macrophage colony-stimulating factor production(GO:0036301) interleukin-21 secretion(GO:0072619) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.1 1.0 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.7 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.4 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.4 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.4 GO:1902567 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.1 0.5 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 2.3 GO:0008228 opsonization(GO:0008228)
0.1 1.9 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 1.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 2.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.7 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.4 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.4 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.4 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.7 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.4 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.5 GO:0019249 lactate biosynthetic process(GO:0019249)
0.1 1.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 3.1 GO:0042730 fibrinolysis(GO:0042730)
0.1 1.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 2.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.6 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 1.1 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.4 GO:1904640 response to methionine(GO:1904640)
0.1 0.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.5 GO:0061042 vascular wound healing(GO:0061042)
0.1 2.5 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 0.4 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.5 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.3 GO:0035425 autocrine signaling(GO:0035425)
0.1 2.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.2 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.4 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 1.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 2.4 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.5 GO:0042262 DNA protection(GO:0042262)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 2.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:1901671 positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.6 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.5 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.6 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.7 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0070105 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.4 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.0 0.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.5 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.9 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 1.0 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.5 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 2.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.6 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.0 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.9 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.3 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.2 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.4 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 1.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.0 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.9 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.1 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 1.7 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 1.1 GO:0031295 T cell costimulation(GO:0031295)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.5 3.0 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.3 1.0 GO:0097444 spine apparatus(GO:0097444)
0.3 1.7 GO:1990037 Lewy body core(GO:1990037)
0.3 0.8 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 3.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.8 GO:0097255 R2TP complex(GO:0097255)
0.1 2.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.3 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.5 GO:0070552 BRISC complex(GO:0070552)
0.1 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 1.1 GO:0032433 filopodium tip(GO:0032433)
0.1 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.9 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 1.4 GO:0098553 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 3.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.6 GO:0043194 axon initial segment(GO:0043194)
0.0 2.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 4.6 GO:0043296 apical junction complex(GO:0043296)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 1.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 4.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 17.4 GO:0009986 cell surface(GO:0009986)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 7.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.9 3.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.8 2.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.7 3.5 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.6 4.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 2.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.5 2.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.3 3.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 1.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.3 0.8 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.3 2.9 GO:0004849 uridine kinase activity(GO:0004849)
0.3 1.5 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 1.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 0.5 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 1.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 0.5 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.2 3.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 2.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.4 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 2.4 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.6 GO:0033265 choline binding(GO:0033265)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 2.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 2.3 GO:0051400 BH domain binding(GO:0051400)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.8 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.3 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 1.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 10.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.5 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 3.6 GO:0030507 spectrin binding(GO:0030507)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 5.6 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.1 0.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.5 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.0 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 2.0 GO:0001848 complement binding(GO:0001848)
0.1 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 4.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 1.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.4 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.2 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 2.3 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 12.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.6 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.5 PID AURORA B PATHWAY Aurora B signaling
0.1 1.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 5.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 ST GAQ PATHWAY G alpha q Pathway
0.0 0.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.9 ST ADRENERGIC Adrenergic Pathway
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 9.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 5.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 3.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 5.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 3.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 11.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 2.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 3.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.9 REACTOME OPSINS Genes involved in Opsins
0.1 2.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 3.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 2.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 2.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.5 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 2.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 2.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation