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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CEBPB

Z-value: 1.88

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Transcription factors associated with CEBPB

Gene Symbol Gene ID Gene Info
CEBPB
ENSG00000172216.4 CCAAT enhancer binding protein beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPBhg19_v2_chr20_+_48807351_488073840.573.1e-03Click!

Activity profile of CEBPB motif

Sorted Z-values of CEBPB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_139163491 11.25 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_+_212782012 10.81 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr11_-_102668879 10.58 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr15_-_80263506 10.37 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr15_+_89182178 10.32 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 10.30 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr5_-_150473127 10.12 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr15_+_89181974 8.92 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr5_-_141704566 7.99 ENST00000344120.4
ENST00000434127.2
SPRY4
sprouty homolog 4 (Drosophila)
chr6_+_127898312 6.96 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr6_+_32812568 6.65 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chrX_+_9431324 5.87 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr12_-_56236734 5.35 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chr5_+_125758865 5.26 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr5_+_125758813 5.22 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr6_+_126102292 5.07 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr1_-_149908217 4.43 ENST00000369140.3
MTMR11
myotubularin related protein 11
chr11_-_3078616 4.23 ENST00000401769.3
ENST00000278224.9
ENST00000397114.3
ENST00000380525.4
CARS
cysteinyl-tRNA synthetase
chr11_-_3078838 4.22 ENST00000397111.5
CARS
cysteinyl-tRNA synthetase
chr3_-_71179699 4.02 ENST00000497355.1
FOXP1
forkhead box P1
chr2_-_175711133 3.92 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr15_+_41245160 3.82 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr20_+_361890 3.68 ENST00000449710.1
ENST00000422053.2
TRIB3
tribbles pseudokinase 3
chr7_-_115670792 3.64 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr1_-_149908710 3.63 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
MTMR11
myotubularin related protein 11
chr17_+_29248953 3.58 ENST00000581285.1
ADAP2
ArfGAP with dual PH domains 2
chr2_+_65216462 3.54 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr20_+_361261 3.53 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chr7_-_115670804 3.29 ENST00000320239.7
TFEC
transcription factor EC
chr1_+_28586006 3.22 ENST00000253063.3
SESN2
sestrin 2
chr7_+_28725585 3.16 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr6_-_32812420 3.15 ENST00000374881.2
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr15_+_62359175 3.06 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chr12_-_6451186 2.94 ENST00000540022.1
ENST00000536194.1
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr15_+_71145578 2.69 ENST00000544974.2
ENST00000558546.1
LRRC49
leucine rich repeat containing 49
chr6_-_17987694 2.63 ENST00000378814.5
ENST00000378843.2
ENST00000378826.2
ENST00000378816.5
ENST00000259711.6
ENST00000502704.1
KIF13A
kinesin family member 13A
chr16_+_56970567 2.54 ENST00000563911.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr9_-_117568365 2.54 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr13_+_26828275 2.53 ENST00000381527.3
CDK8
cyclin-dependent kinase 8
chr5_+_52083730 2.52 ENST00000282588.6
ENST00000274311.2
ITGA1
PELO
integrin, alpha 1
pelota homolog (Drosophila)
chr12_-_56236690 2.51 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr4_+_77870856 2.51 ENST00000264893.6
ENST00000502584.1
ENST00000510641.1
SEPT11
septin 11
chr5_-_172756506 2.44 ENST00000265087.4
STC2
stanniocalcin 2
chr12_+_21207503 2.42 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr6_+_31895467 2.38 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr22_+_35776828 2.37 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr13_-_30169807 2.23 ENST00000380752.5
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_-_196577489 2.23 ENST00000609185.1
ENST00000451324.2
ENST00000367433.5
ENST00000367431.4
KCNT2
potassium channel, subfamily T, member 2
chr16_+_56965960 2.18 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr3_-_66551351 2.03 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr12_-_6451235 2.03 ENST00000440083.2
ENST00000162749.2
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr10_+_111765562 2.02 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr1_+_50574585 1.85 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr1_-_36948879 1.83 ENST00000373106.1
ENST00000373104.1
ENST00000373103.1
CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr3_-_66551397 1.83 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr1_-_203198790 1.79 ENST00000367229.1
ENST00000255427.3
ENST00000535569.1
CHIT1
chitinase 1 (chitotriosidase)
chr11_+_62649158 1.75 ENST00000539891.1
ENST00000536981.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_-_36945097 1.75 ENST00000331941.5
ENST00000418048.2
ENST00000338937.5
ENST00000440588.2
CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr5_-_58652788 1.74 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_-_47288162 1.72 ENST00000594991.1
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr19_-_47287990 1.71 ENST00000593713.1
ENST00000598022.1
ENST00000434726.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr4_+_77870960 1.70 ENST00000505788.1
ENST00000510515.1
ENST00000504637.1
SEPT11
septin 11
chr19_+_33865218 1.69 ENST00000585933.2
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr15_-_88799661 1.69 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr1_-_220219775 1.69 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr3_+_141105705 1.67 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chrX_-_118284542 1.65 ENST00000402510.2
KIAA1210
KIAA1210
chr17_+_65374075 1.56 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_-_220220000 1.53 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr15_-_88799384 1.51 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr19_+_36236514 1.49 ENST00000222266.2
PSENEN
presenilin enhancer gamma secretase subunit
chr5_-_179047881 1.49 ENST00000521173.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr1_-_23857698 1.47 ENST00000361729.2
E2F2
E2F transcription factor 2
chr1_-_204380919 1.45 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr19_+_36236491 1.43 ENST00000591949.1
PSENEN
presenilin enhancer gamma secretase subunit
chr12_-_96390063 1.41 ENST00000541929.1
HAL
histidine ammonia-lyase
chr14_+_29236269 1.40 ENST00000313071.4
FOXG1
forkhead box G1
chr17_-_76836963 1.38 ENST00000312010.6
USP36
ubiquitin specific peptidase 36
chr17_-_76836729 1.30 ENST00000587783.1
ENST00000542802.3
ENST00000586531.1
ENST00000589424.1
ENST00000590546.2
USP36
ubiquitin specific peptidase 36
chr5_-_137878887 1.28 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr8_-_38008783 1.21 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr20_+_56136136 1.20 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr1_-_149832704 1.18 ENST00000392933.1
ENST00000369157.2
ENST00000392932.4
HIST2H4B
histone cluster 2, H4b
chr2_-_217559517 1.17 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr17_-_79895154 1.09 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1
pyrroline-5-carboxylate reductase 1
chr17_-_79895097 1.09 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr6_-_55739542 1.08 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr1_+_149804218 1.08 ENST00000610125.1
HIST2H4A
histone cluster 2, H4a
chr9_-_95055956 1.05 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr3_-_48057890 1.04 ENST00000434267.1
MAP4
microtubule-associated protein 4
chrX_-_151619746 1.04 ENST00000370314.4
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr2_+_171785012 1.03 ENST00000234160.4
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr3_+_127770455 1.01 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr19_-_4540486 0.99 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr17_-_64216748 0.98 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_+_5832799 0.98 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr15_-_88799948 0.98 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr5_+_33441053 0.98 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
TARS
threonyl-tRNA synthetase
chr17_+_39846114 0.97 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr19_+_49258775 0.95 ENST00000593756.1
FGF21
fibroblast growth factor 21
chr15_-_49255632 0.95 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr19_+_49259325 0.94 ENST00000222157.3
FGF21
fibroblast growth factor 21
chr6_+_151187615 0.92 ENST00000441122.1
ENST00000423867.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr2_-_220174166 0.92 ENST00000409251.3
ENST00000451506.1
ENST00000295718.2
ENST00000446182.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr9_+_137218362 0.91 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr1_+_239882842 0.90 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr5_+_169780485 0.89 ENST00000377360.4
KCNIP1
Kv channel interacting protein 1
chr12_+_93096759 0.89 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr5_+_38846101 0.86 ENST00000274276.3
OSMR
oncostatin M receptor
chr17_+_29248918 0.85 ENST00000581548.1
ENST00000580525.1
ADAP2
ArfGAP with dual PH domains 2
chr10_+_26727125 0.85 ENST00000376236.4
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr5_+_33440802 0.85 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
TARS
threonyl-tRNA synthetase
chr5_-_76935513 0.85 ENST00000306422.3
OTP
orthopedia homeobox
chrX_-_55024967 0.85 ENST00000545676.1
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr6_+_30687978 0.84 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr17_-_33390667 0.80 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr12_+_57624119 0.79 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr9_-_34691201 0.79 ENST00000378800.3
ENST00000311925.2
CCL19
chemokine (C-C motif) ligand 19
chr12_+_93096619 0.79 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr17_+_65373531 0.77 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr5_+_38845960 0.77 ENST00000502536.1
OSMR
oncostatin M receptor
chr5_-_132113559 0.77 ENST00000448933.1
SEPT8
septin 8
chr2_+_46769798 0.76 ENST00000238738.4
RHOQ
ras homolog family member Q
chr6_-_48036363 0.76 ENST00000543600.1
ENST00000398738.2
ENST00000339488.4
PTCHD4
patched domain containing 4
chr2_+_113885138 0.73 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr1_-_150601588 0.71 ENST00000513281.1
ENST00000361631.5
ENST00000361532.5
ENSA
endosulfine alpha
chr6_+_151187074 0.70 ENST00000367308.4
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr5_+_179105615 0.67 ENST00000514383.1
CANX
calnexin
chr3_+_141105235 0.67 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr10_+_50507232 0.65 ENST00000374144.3
C10orf71
chromosome 10 open reading frame 71
chr16_-_4323015 0.65 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr3_+_157154578 0.65 ENST00000295927.3
PTX3
pentraxin 3, long
chr10_+_50507181 0.64 ENST00000323868.4
C10orf71
chromosome 10 open reading frame 71
chr3_+_99833755 0.63 ENST00000489081.1
CMSS1
cms1 ribosomal small subunit homolog (yeast)
chrX_+_13587712 0.63 ENST00000361306.1
ENST00000380602.3
EGFL6
EGF-like-domain, multiple 6
chr7_+_99006550 0.63 ENST00000222969.5
BUD31
BUD31 homolog (S. cerevisiae)
chr12_-_46662772 0.63 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
SLC38A1
solute carrier family 38, member 1
chr20_+_39969519 0.62 ENST00000373257.3
LPIN3
lipin 3
chr15_-_64665911 0.61 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
CTD-2116N17.1
Uncharacterized protein
chr6_+_31939608 0.61 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr5_-_35230771 0.60 ENST00000342362.5
PRLR
prolactin receptor
chr2_-_179567206 0.59 ENST00000414766.1
TTN
titin
chr19_-_36236292 0.59 ENST00000378975.3
ENST00000412391.2
ENST00000292879.5
U2AF1L4
U2 small nuclear RNA auxiliary factor 1-like 4
chr12_-_57914275 0.59 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DDIT3
DNA-damage-inducible transcript 3
chr17_-_38978847 0.57 ENST00000269576.5
KRT10
keratin 10
chr17_+_56315936 0.57 ENST00000543544.1
LPO
lactoperoxidase
chr1_+_25757376 0.56 ENST00000399766.3
ENST00000399763.3
ENST00000374343.4
TMEM57
transmembrane protein 57
chr10_+_45495898 0.55 ENST00000298299.3
ZNF22
zinc finger protein 22
chr20_-_32700075 0.55 ENST00000374980.2
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr17_+_56315787 0.55 ENST00000262290.4
ENST00000421678.2
LPO
lactoperoxidase
chr3_-_3151664 0.53 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
IL5RA
interleukin 5 receptor, alpha
chr1_-_27952741 0.52 ENST00000399173.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr6_+_31895254 0.52 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr19_-_44123734 0.51 ENST00000598676.1
ZNF428
zinc finger protein 428
chr17_+_28268623 0.50 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5
EF-hand calcium binding domain 5
chr3_-_99833333 0.49 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L
filamin A interacting protein 1-like
chr3_+_138067521 0.49 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr10_+_57358750 0.49 ENST00000512524.2
MTRNR2L5
MT-RNR2-like 5
chr19_+_49497121 0.49 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr10_+_81272287 0.48 ENST00000520547.2
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr7_-_50860565 0.48 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chr4_+_71063641 0.48 ENST00000514097.1
ODAM
odontogenic, ameloblast asssociated
chr3_-_3152031 0.47 ENST00000383846.1
ENST00000427088.1
ENST00000446632.2
ENST00000438560.1
IL5RA
interleukin 5 receptor, alpha
chr17_+_43239191 0.46 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr20_+_8112824 0.46 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chrX_-_70288234 0.43 ENST00000276105.3
ENST00000374274.3
SNX12
sorting nexin 12
chr7_-_76829125 0.42 ENST00000248598.5
FGL2
fibrinogen-like 2
chr3_+_138067666 0.42 ENST00000475711.1
ENST00000464896.1
MRAS
muscle RAS oncogene homolog
chr7_+_99006232 0.41 ENST00000403633.2
BUD31
BUD31 homolog (S. cerevisiae)
chrX_-_106243451 0.41 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr19_-_33360647 0.39 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr13_+_77522632 0.39 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr19_-_44124019 0.39 ENST00000300811.3
ZNF428
zinc finger protein 428
chr5_-_145562147 0.39 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS
leucyl-tRNA synthetase
chr11_-_119999611 0.39 ENST00000529044.1
TRIM29
tripartite motif containing 29
chr12_+_10124001 0.39 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
CLEC12A
C-type lectin domain family 12, member A
chr12_+_57624085 0.38 ENST00000553474.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr22_-_41258074 0.38 ENST00000307221.4
DNAJB7
DnaJ (Hsp40) homolog, subfamily B, member 7
chr14_+_39735411 0.37 ENST00000603904.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr20_+_2821340 0.37 ENST00000380445.3
ENST00000380469.3
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr22_+_41258250 0.37 ENST00000544094.1
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr7_-_48068699 0.36 ENST00000412142.1
ENST00000395572.2
SUN3
Sad1 and UNC84 domain containing 3
chr12_+_57623869 0.35 ENST00000414700.3
ENST00000557703.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr5_-_35230649 0.35 ENST00000382002.5
PRLR
prolactin receptor
chr17_-_46703826 0.34 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr6_+_31895480 0.32 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr19_-_36004543 0.32 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chr3_+_141106458 0.30 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr4_-_38858428 0.30 ENST00000436693.2
ENST00000508254.1
ENST00000514655.1
ENST00000506146.1
TLR6
TLR1
toll-like receptor 6
toll-like receptor 1
chr21_-_44495919 0.30 ENST00000398158.1
CBS
cystathionine-beta-synthase
chr11_-_119999539 0.30 ENST00000541857.1
TRIM29
tripartite motif containing 29
chr2_+_169926047 0.30 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr21_-_46334186 0.28 ENST00000522931.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr3_+_12392971 0.27 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr16_-_70323422 0.27 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr1_-_20250110 0.26 ENST00000375116.3
PLA2G2E
phospholipase A2, group IIE
chr7_-_48068643 0.25 ENST00000453192.2
SUN3
Sad1 and UNC84 domain containing 3
chr7_-_48068671 0.24 ENST00000297325.4
SUN3
Sad1 and UNC84 domain containing 3
chr2_+_187350973 0.24 ENST00000544130.1
ZC3H15
zinc finger CCCH-type containing 15
chr13_-_103719196 0.24 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 29.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.6 10.8 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
2.8 8.5 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
2.5 10.1 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.4 4.2 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
1.1 3.2 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.9 7.9 GO:0001554 luteolysis(GO:0001554)
0.9 7.0 GO:0006868 glutamine transport(GO:0006868)
0.8 3.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.8 4.0 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.8 2.4 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.8 3.9 GO:0032474 otolith morphogenesis(GO:0032474)
0.6 3.1 GO:1904640 response to methionine(GO:1904640)
0.5 1.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.5 11.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.5 1.8 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.5 0.9 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.4 2.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.4 1.6 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.4 1.2 GO:1904253 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.4 1.2 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.4 5.0 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.4 1.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.4 1.8 GO:0060356 leucine import(GO:0060356)
0.3 1.0 GO:0039019 pronephric nephron development(GO:0039019)
0.3 10.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.3 1.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.3 1.0 GO:0061386 closure of optic fissure(GO:0061386)
0.3 1.6 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3 2.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.3 2.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.3 1.5 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.3 10.6 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.3 4.7 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.3 1.6 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.3 2.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.3 0.8 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.3 1.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 2.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.2 1.7 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 0.9 GO:1990502 dense core granule maturation(GO:1990502)
0.2 1.7 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 2.0 GO:0006983 ER overload response(GO:0006983)
0.2 5.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 5.1 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.2 1.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 3.8 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.2 1.0 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.2 0.8 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.2 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 0.5 GO:0080154 regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427)
0.1 1.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 2.9 GO:0007220 Notch receptor processing(GO:0007220)
0.1 3.6 GO:0097186 amelogenesis(GO:0097186)
0.1 0.4 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.9 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.4 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.1 0.8 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 1.8 GO:0006449 regulation of translational termination(GO:0006449)
0.1 2.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 2.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.1 0.5 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.5 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 3.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 9.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.1 0.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.8 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.1 1.0 GO:0034392 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.5 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 7.5 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 0.3 GO:1901558 response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.3 GO:1990262 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1 1.0 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 2.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.5 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.8 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 5.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.9 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.6 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.7 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 2.0 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 6.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:1905174 metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.0 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.5 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 2.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 4.0 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 2.6 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 1.5 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.1 9.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.8 2.5 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.8 4.7 GO:1990037 Lewy body core(GO:1990037)
0.5 1.6 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.4 2.9 GO:0097452 GAIT complex(GO:0097452)
0.4 28.4 GO:0015030 Cajal body(GO:0015030)
0.3 3.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 2.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.7 GO:0070552 BRISC complex(GO:0070552)
0.2 1.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.1 12.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.6 GO:0089701 U2AF(GO:0089701)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 5.9 GO:0005876 spindle microtubule(GO:0005876)
0.1 2.5 GO:0016592 mediator complex(GO:0016592)
0.1 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0097255 R2TP complex(GO:0097255)
0.0 8.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 7.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 9.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 4.2 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 2.4 GO:0005871 kinesin complex(GO:0005871)
0.0 2.9 GO:0035580 specific granule lumen(GO:0035580) tertiary granule lumen(GO:1904724)
0.0 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0030897 HOPS complex(GO:0030897)
0.0 11.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 8.2 GO:0043235 receptor complex(GO:0043235)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 3.7 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 1.8 GO:0005903 brush border(GO:0005903)
0.0 0.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.5 GO:0008859 exoribonuclease II activity(GO:0008859)
2.8 8.5 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
1.7 15.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
1.3 3.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.1 3.2 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
1.0 5.0 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.9 3.6 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.9 3.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.8 2.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.5 4.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.5 10.4 GO:0051400 BH domain binding(GO:0051400)
0.5 3.2 GO:0070728 leucine binding(GO:0070728)
0.5 1.8 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.4 2.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4 1.6 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.4 1.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.4 7.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.4 2.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.4 1.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.3 1.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.3 1.6 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.3 4.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 9.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 2.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.3 2.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 0.8 GO:0032427 GBD domain binding(GO:0032427)
0.2 0.7 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.2 1.7 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 1.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 0.9 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 0.8 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 9.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 0.8 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 1.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.4 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 18.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.8 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:0098809 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 2.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 2.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 3.6 GO:0001848 complement binding(GO:0001848)
0.1 1.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.1 GO:0070700 BMP receptor binding(GO:0070700)
0.1 6.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 3.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 2.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 2.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 1.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 4.6 GO:0043621 protein self-association(GO:0043621)
0.1 21.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 2.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.9 GO:0043495 protein anchor(GO:0043495)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 2.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 2.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 2.9 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 2.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.9 GO:0004601 peroxidase activity(GO:0004601)
0.0 1.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 12.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 5.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 10.8 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 10.4 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.0 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 4.3 PID SHP2 PATHWAY SHP2 signaling
0.1 1.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.2 PID INSULIN PATHWAY Insulin Pathway
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 4.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.5 24.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 16.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.4 14.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.4 32.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 9.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 6.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 2.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.2 5.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 6.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 2.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.0 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 2.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 2.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 3.9 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling