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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CEBPG

Z-value: 0.57

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Transcription factors associated with CEBPG

Gene Symbol Gene ID Gene Info
CEBPG
ENSG00000153879.4 CCAAT enhancer binding protein gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPGhg19_v2_chr19_+_33865218_338652540.563.9e-03Click!

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102668879 2.63 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr21_+_43619796 2.53 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr2_+_102721023 1.79 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr9_+_115913222 1.72 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr5_-_121413974 1.69 ENST00000231004.4
LOX
lysyl oxidase
chr12_-_57522813 1.47 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr21_+_34775181 1.43 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr5_+_125758865 1.42 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr5_+_125758813 1.41 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr17_+_80332153 1.10 ENST00000313135.2
UTS2R
urotensin 2 receptor
chr21_-_35899113 1.10 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr11_-_72504681 0.94 ENST00000538536.1
ENST00000543304.1
ENST00000540587.1
ENST00000334805.6
STARD10
StAR-related lipid transfer (START) domain containing 10
chr21_-_37852359 0.90 ENST00000399137.1
ENST00000399135.1
CLDN14
claudin 14
chr1_+_165864800 0.88 ENST00000469256.2
UCK2
uridine-cytidine kinase 2
chr6_+_37897735 0.88 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr3_-_4793274 0.83 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr1_+_165864821 0.71 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr2_-_152146385 0.70 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr20_+_816695 0.66 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr6_+_31895467 0.61 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr19_-_49496557 0.59 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr1_+_172389821 0.55 ENST00000367727.4
C1orf105
chromosome 1 open reading frame 105
chr1_-_153321301 0.54 ENST00000368739.3
PGLYRP4
peptidoglycan recognition protein 4
chr1_-_243326612 0.54 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr5_+_49962772 0.53 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr7_-_83824169 0.52 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr18_+_72167096 0.49 ENST00000324301.8
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr20_+_361890 0.47 ENST00000449710.1
ENST00000422053.2
TRIB3
tribbles pseudokinase 3
chr12_-_323689 0.47 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr19_+_6887571 0.46 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr12_+_72058130 0.46 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr4_-_76598544 0.44 ENST00000515457.1
ENST00000357854.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr10_+_26986582 0.44 ENST00000376215.5
ENST00000376203.5
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr22_-_50523760 0.44 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_-_161277210 0.44 ENST00000491222.2
MPZ
myelin protein zero
chr11_-_104972158 0.43 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr16_+_57220193 0.43 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
RSPRY1
ring finger and SPRY domain containing 1
chr5_-_146258291 0.41 ENST00000394411.4
ENST00000453001.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr19_-_20844343 0.39 ENST00000595405.1
ZNF626
zinc finger protein 626
chr12_-_114841703 0.38 ENST00000526441.1
TBX5
T-box 5
chr19_+_45394477 0.37 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr12_-_96390063 0.37 ENST00000541929.1
HAL
histidine ammonia-lyase
chr19_-_4540486 0.37 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr1_-_1711508 0.35 ENST00000378625.1
NADK
NAD kinase
chr20_+_361261 0.35 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chr4_-_70826725 0.34 ENST00000353151.3
CSN2
casein beta
chr3_+_130569429 0.33 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr4_+_175839506 0.32 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM29
ADAM metallopeptidase domain 29
chr7_-_14026063 0.32 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr14_-_80677815 0.32 ENST00000557125.1
ENST00000555750.1
DIO2
deiodinase, iodothyronine, type II
chr4_+_175839551 0.31 ENST00000404450.4
ENST00000514159.1
ADAM29
ADAM metallopeptidase domain 29
chr1_-_204183071 0.30 ENST00000308302.3
GOLT1A
golgi transport 1A
chr11_-_119187826 0.30 ENST00000264036.4
MCAM
melanoma cell adhesion molecule
chr8_+_38585704 0.29 ENST00000519416.1
ENST00000520615.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr13_-_46679185 0.29 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr13_-_46679144 0.28 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr8_-_121824374 0.27 ENST00000517992.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr6_-_30710265 0.27 ENST00000438162.1
ENST00000454845.1
FLOT1
flotillin 1
chr11_-_18270182 0.26 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr4_+_71248795 0.25 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr2_+_226265364 0.25 ENST00000272907.6
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr19_+_49259325 0.24 ENST00000222157.3
FGF21
fibroblast growth factor 21
chr1_+_75594119 0.24 ENST00000294638.5
LHX8
LIM homeobox 8
chr4_+_70796784 0.24 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr3_+_157154578 0.23 ENST00000295927.3
PTX3
pentraxin 3, long
chr22_-_30867973 0.23 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
SEC14L3
SEC14-like 3 (S. cerevisiae)
chrX_+_47082408 0.23 ENST00000518022.1
ENST00000276052.6
CDK16
cyclin-dependent kinase 16
chr12_-_69080590 0.22 ENST00000433116.2
ENST00000500695.2
RP11-637A17.2
RP11-637A17.2
chr8_+_38586068 0.22 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr22_-_42765174 0.22 ENST00000432473.1
ENST00000412060.1
ENST00000424852.1
Z83851.1
Z83851.1
chr19_+_49496705 0.22 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr9_+_136399929 0.21 ENST00000393060.1
ADAMTSL2
ADAMTS-like 2
chr1_+_196743912 0.20 ENST00000367425.4
CFHR3
complement factor H-related 3
chr14_+_96722539 0.20 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr2_-_113594279 0.19 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr2_-_89545079 0.19 ENST00000468494.1
IGKV2-30
immunoglobulin kappa variable 2-30
chr12_-_95510743 0.18 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr11_+_59824127 0.18 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr8_-_6795823 0.18 ENST00000297435.2
DEFA4
defensin, alpha 4, corticostatin
chr19_+_49258775 0.17 ENST00000593756.1
FGF21
fibroblast growth factor 21
chr17_-_61850894 0.17 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47
coiled-coil domain containing 47
chr12_-_53074182 0.17 ENST00000252244.3
KRT1
keratin 1
chr1_+_196743943 0.17 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr6_+_31895254 0.17 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr17_-_79895154 0.17 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1
pyrroline-5-carboxylate reductase 1
chr12_-_13248598 0.16 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr4_+_184020398 0.16 ENST00000403733.3
ENST00000378925.3
WWC2
WW and C2 domain containing 2
chr11_+_59824060 0.16 ENST00000395032.2
ENST00000358152.2
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr2_+_113825547 0.16 ENST00000341010.2
ENST00000337569.3
IL1F10
interleukin 1 family, member 10 (theta)
chr17_-_42200958 0.16 ENST00000336057.5
HDAC5
histone deacetylase 5
chr5_-_146258205 0.16 ENST00000394413.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr17_-_79895097 0.16 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr10_-_92681033 0.16 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr13_+_30002741 0.15 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr19_+_49497121 0.15 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr9_+_80912059 0.15 ENST00000347159.2
ENST00000376588.3
PSAT1
phosphoserine aminotransferase 1
chr17_-_42200996 0.14 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5
histone deacetylase 5
chr3_+_178253993 0.14 ENST00000420517.2
ENST00000452583.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr12_+_53835383 0.14 ENST00000429243.2
PRR13
proline rich 13
chr3_+_68055366 0.13 ENST00000496687.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr19_-_35992780 0.13 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chrX_-_73834449 0.13 ENST00000332687.6
ENST00000349225.2
RLIM
ring finger protein, LIM domain interacting
chr10_-_70092635 0.13 ENST00000309049.4
PBLD
phenazine biosynthesis-like protein domain containing
chr16_+_6069586 0.13 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr20_+_54987168 0.13 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr14_+_45366518 0.12 ENST00000557112.1
C14orf28
chromosome 14 open reading frame 28
chr10_-_61469837 0.12 ENST00000395348.3
SLC16A9
solute carrier family 16, member 9
chr6_+_167704798 0.12 ENST00000230256.3
UNC93A
unc-93 homolog A (C. elegans)
chr3_-_42306248 0.12 ENST00000334681.5
CCK
cholecystokinin
chr1_+_248201474 0.12 ENST00000366479.2
OR2L2
olfactory receptor, family 2, subfamily L, member 2
chr6_-_135271219 0.12 ENST00000367847.2
ENST00000367845.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr12_+_57522258 0.12 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr17_+_47287749 0.11 ENST00000419580.2
ABI3
ABI family, member 3
chr6_+_167704838 0.11 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chr12_+_57522439 0.11 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr19_+_49496782 0.10 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr4_+_71226468 0.10 ENST00000226460.4
SMR3A
submaxillary gland androgen regulated protein 3A
chr11_+_18287801 0.10 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr12_-_57039739 0.10 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr6_-_29055090 0.10 ENST00000377173.2
OR2B3
olfactory receptor, family 2, subfamily B, member 3
chr12_-_54758251 0.10 ENST00000267015.3
ENST00000551809.1
GPR84
G protein-coupled receptor 84
chr7_-_121944491 0.10 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr20_+_54987305 0.10 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr3_+_73110810 0.09 ENST00000533473.1
EBLN2
endogenous Bornavirus-like nucleoprotein 2
chr11_+_18287721 0.09 ENST00000356524.4
SAA1
serum amyloid A1
chr21_+_33671264 0.09 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr11_-_26593677 0.09 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr6_-_135271260 0.09 ENST00000265605.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr11_-_18258342 0.08 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr19_-_40971667 0.08 ENST00000263368.4
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr4_+_74269956 0.08 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB
albumin
chr15_-_34628951 0.08 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr12_+_129028500 0.08 ENST00000315208.8
TMEM132C
transmembrane protein 132C
chr11_+_60048053 0.07 ENST00000337908.4
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr6_+_31895480 0.07 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr11_-_102576537 0.07 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr6_-_133055896 0.07 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr14_-_70263979 0.07 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr3_-_194072019 0.07 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chr14_+_45366472 0.06 ENST00000325192.3
C14orf28
chromosome 14 open reading frame 28
chr19_-_36822595 0.06 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
LINC00665
long intergenic non-protein coding RNA 665
chr5_-_145562147 0.06 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS
leucyl-tRNA synthetase
chr12_+_53835508 0.06 ENST00000551003.1
ENST00000549068.1
ENST00000549740.1
ENST00000546581.1
ENST00000549581.1
ENST00000541275.1
PRR13
PCBP2
proline rich 13
poly(rC) binding protein 2
chr17_-_64225508 0.06 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_-_89310012 0.06 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr11_+_60048129 0.06 ENST00000355131.3
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr11_-_72504637 0.06 ENST00000536377.1
ENST00000359373.5
STARD10
ARAP1
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr14_+_39703112 0.06 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr18_-_29340827 0.05 ENST00000269205.5
SLC25A52
solute carrier family 25, member 52
chr14_+_105046094 0.05 ENST00000331952.2
C14orf180
chromosome 14 open reading frame 180
chrX_-_73512411 0.05 ENST00000602576.1
ENST00000429124.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr14_+_62462541 0.05 ENST00000430451.2
SYT16
synaptotagmin XVI
chr13_-_36788718 0.05 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr17_+_61851504 0.04 ENST00000359353.5
ENST00000389924.2
DDX42
DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr16_+_33020496 0.04 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr21_+_33671160 0.04 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chrX_+_46937745 0.04 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN
regucalcin
chr14_+_21387508 0.04 ENST00000555624.1
RP11-84C10.2
RP11-84C10.2
chr2_-_21266935 0.03 ENST00000233242.1
APOB
apolipoprotein B
chr11_-_40315640 0.03 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr2_+_11674213 0.03 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr19_+_47538560 0.03 ENST00000439365.2
ENST00000594670.1
NPAS1
neuronal PAS domain protein 1
chr12_-_96390108 0.02 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr12_-_13248562 0.01 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chr1_-_60539405 0.01 ENST00000450089.2
C1orf87
chromosome 1 open reading frame 87
chr17_+_4699439 0.01 ENST00000270586.3
PSMB6
proteasome (prosome, macropain) subunit, beta type, 6
chr1_-_60539422 0.01 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr1_+_111770232 0.01 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr9_+_117085336 0.01 ENST00000259396.8
ENST00000538816.1
ORM1
orosomucoid 1
chr3_+_40498783 0.01 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
RPL14
ribosomal protein L14
chr16_-_3350614 0.00 ENST00000268674.2
TIGD7
tigger transposable element derived 7

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.6 1.8 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.4 1.6 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.4 1.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.4 1.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.2 0.5 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.2 1.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.7 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 1.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.3 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.5 GO:0048880 sensory system development(GO:0048880)
0.1 0.5 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 1.0 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.4 GO:1904640 response to methionine(GO:1904640)
0.1 0.4 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 2.7 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.2 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.3 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.2 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 1.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.0 0.9 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.4 GO:0098743 cell aggregation(GO:0098743)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.0 GO:1903630 L-ascorbic acid biosynthetic process(GO:0019853) positive regulation of calcium-transporting ATPase activity(GO:1901896) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.4 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.5 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 5.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.4 1.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3 1.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 1.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.2 1.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 0.5 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.5 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 2.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones