ISMARA results: CPEB1

Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation

Downloads

Results for CPEB1

Z-value: 0.73

Motif logo

Transcription factors associated with CPEB1

Gene Symbol	Gene ID	Gene Info
CPEB1 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000214575.5	cytoplasmic polyadenylation element binding protein 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CPEB1	hg19_v2_chr15_-_83316254_83316368	-0.27	1.9e-01	Click!

Activity profile of CPEB1 motif

Sorted Z-values of CPEB1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_+_84630053 Show fit	2.24	ENST00000394838.2 ENST00000370682.3 ENST00000432111.1	PRKACB Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase, cAMP-dependent, catalytic, beta
chr1_+_61869748 Show fit	2.23	ENST00000357977.5	NFIA Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor I/A
chr1_+_84630645 Show fit	2.11	ENST00000394839.2	PRKACB Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase, cAMP-dependent, catalytic, beta
chr4_-_102267953 Show fit	2.10	ENST00000523694.2 ENST00000507176.1	PPP3CA Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_-_18480260 Show fit	1.92	ENST00000454909.2	SATB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	SATB homeobox 1
chr13_+_31480328 Show fit	1.83	ENST00000380482.4	MEDAG Ensembl NCBI GeneCards UniProt NextProt Show fit	mesenteric estrogen-dependent adipogenesis
chr7_-_11871815 Show fit	1.75	ENST00000423059.4	THSD7A Ensembl NCBI GeneCards UniProt NextProt Show fit	thrombospondin, type I, domain containing 7A
chr1_+_164528866 Show fit	1.61	ENST00000420696.2	PBX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	pre-B-cell leukemia homeobox 1
chr9_-_20622478 Show fit	1.53	ENST00000355930.6 ENST00000380338.4	MLLT3 Ensembl NCBI GeneCards UniProt NextProt Show fit	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr20_+_42574317 Show fit	1.49	ENST00000358131.5	TOX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	TOX high mobility group box family member 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of CPEB1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	5.1	GO:0097338	response to clozapine(GO:0097338)
1.6	4.7	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.0	4.6	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.1	2.7	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	2.7	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	2.2	GO:0072189	ureter development(GO:0072189)
0.1	2.1	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.6	1.8	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4	1.6	GO:0003138	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1	1.5	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)

Showing 1 to 10 of 123 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.5	4.7	GO:0005955	calcineurin complex(GO:0005955)
0.0	4.2	GO:0032993	protein-DNA complex(GO:0032993)
0.0	4.2	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	2.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4	1.8	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	1.5	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	1.3	GO:0071953	elastic fiber(GO:0071953)
0.0	1.3	GO:0000145	exocyst(GO:0000145)
0.0	1.2	GO:0005720	nuclear heterochromatin(GO:0005720)

Showing 1 to 10 of 39 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.4	4.8	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5	4.7	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	4.5	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	4.2	GO:0003714	transcription corepressor activity(GO:0003714)
0.3	1.8	GO:0030348	syntaxin-3 binding(GO:0030348)
0.1	1.5	GO:0003680	AT DNA binding(GO:0003680)
0.0	1.4	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	1.3	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.2	1.2	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)

Showing 1 to 10 of 67 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	4.9	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	4.7	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	3.9	PID E2F PATHWAY	E2F transcription factor network
0.0	2.4	PID AURORA B PATHWAY	Aurora B signaling
0.0	2.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	2.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.8	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	1.7	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	1.7	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events

Showing 1 to 10 of 25 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	5.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	3.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	2.1	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	1.8	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	1.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	1.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.0	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules

Showing 1 to 10 of 26 entries

Results for CPEB1

Z-value: 0.73

Motif logo

Transcription factors associated with CPEB1

Activity-expression correlation:

Activity profile of CPEB1 motif

Sorted Z-values of CPEB1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CPEB1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: