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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CREB1

Z-value: 0.93

Motif logo

Transcription factors associated with CREB1

Gene Symbol Gene ID Gene Info
ENSG00000118260.10 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB1hg19_v2_chr2_+_208394658_208394692-0.433.2e-02Click!

Activity profile of CREB1 motif

Sorted Z-values of CREB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_132628847 1.46 ENST00000397333.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr8_+_17104539 1.33 ENST00000521829.1
ENST00000521005.1
vacuolar protein sorting 37 homolog A (S. cerevisiae)
chr17_-_72869140 1.07 ENST00000583917.1
ENST00000293195.5
ENST00000442102.2
ferredoxin reductase
chr17_-_72869086 1.06 ENST00000581530.1
ENST00000420580.2
ENST00000455107.2
ENST00000413947.2
ENST00000581219.1
ENST00000582944.1
ferredoxin reductase
chr4_-_153457197 1.04 ENST00000281708.4
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr12_+_132628963 1.03 ENST00000330579.1
nucleolar complex associated 4 homolog (S. cerevisiae)
chr8_+_25042192 0.91 ENST00000410074.1
dedicator of cytokinesis 5
chr5_+_72861560 0.87 ENST00000296792.4
ENST00000509005.1
ENST00000543251.1
ENST00000508686.1
ENST00000508491.1
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr7_-_1199781 0.85 ENST00000397083.1
ENST00000401903.1
ENST00000316495.3
zinc finger, AN1-type domain 2A
chr22_-_26879734 0.83 ENST00000422379.2
ENST00000336873.5
ENST00000398145.2
Hermansky-Pudlak syndrome 4
chr16_-_90038866 0.82 ENST00000314994.3
CENPB DNA-binding domains containing 1
chr1_-_213031418 0.82 ENST00000356684.3
ENST00000426161.1
ENST00000424044.1
FLVCR1 antisense RNA 1 (head to head)
chr10_-_113943447 0.81 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
glycerol-3-phosphate acyltransferase, mitochondrial
chr3_-_45017609 0.79 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
zinc finger, DHHC-type containing 3
chr11_-_64851496 0.77 ENST00000404147.3
ENST00000275517.3
cell division cycle associated 5
chr9_+_114393581 0.75 ENST00000313525.3
DnaJ (Hsp40) homolog, subfamily C , member 25
chr22_+_26879817 0.72 ENST00000215917.7
SRR1 domain containing
chr17_+_17380294 0.72 ENST00000268711.3
ENST00000580462.1
mediator complex subunit 9
chr12_+_58166370 0.68 ENST00000300209.8
methyltransferase like 21B
chr16_+_19078960 0.68 ENST00000568985.1
ENST00000566110.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_+_45017722 0.67 ENST00000265564.7
exosome component 7
chr13_+_49822041 0.67 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
cytidine and dCMP deaminase domain containing 1
chr16_+_19079215 0.66 ENST00000544894.2
ENST00000561858.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr16_+_19079311 0.65 ENST00000569127.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr12_-_58165870 0.64 ENST00000257848.7
methyltransferase like 1
chr18_+_268148 0.63 ENST00000581677.1
RP11-705O1.8
chr5_-_133304473 0.62 ENST00000231512.3
chromosome 5 open reading frame 15
chr3_+_196295482 0.60 ENST00000440469.1
ENST00000311630.6
F-box protein 45
chr4_+_39460659 0.59 ENST00000513731.1
lipoic acid synthetase
chr17_-_49198216 0.59 ENST00000262013.7
ENST00000357122.4
sperm associated antigen 9
chr4_+_39460689 0.59 ENST00000381846.1
lipoic acid synthetase
chr3_+_44771088 0.58 ENST00000396048.2
zinc finger protein 501
chr16_-_88772670 0.58 ENST00000562544.1
ring finger protein 166
chr4_+_39460620 0.56 ENST00000340169.2
ENST00000261434.3
lipoic acid synthetase
chr19_-_12807395 0.54 ENST00000587955.1
F-box and WD repeat domain containing 9
chr8_-_144623595 0.54 ENST00000262577.5
zinc finger CCCH-type containing 3
chr17_+_685513 0.54 ENST00000304478.4
RNA methyltransferase like 1
chr3_+_128598433 0.53 ENST00000308982.7
ENST00000514336.1
acyl-CoA dehydrogenase family, member 9
chr16_-_20753114 0.53 ENST00000396083.2
THUMP domain containing 1
chr17_-_8151353 0.52 ENST00000315684.8
CTS telomere maintenance complex component 1
chr19_+_33182823 0.50 ENST00000397061.3
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr6_+_126661253 0.50 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
centromere protein W
chr16_+_88772866 0.50 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr17_-_49198095 0.50 ENST00000505279.1
sperm associated antigen 9
chr19_+_58341656 0.48 ENST00000442832.4
ENST00000594901.1
zinc finger protein 587B
chr12_-_120884175 0.48 ENST00000546954.1
TP53 regulated inhibitor of apoptosis 1
chr11_+_67195917 0.48 ENST00000524934.1
ENST00000539188.1
ENST00000312629.5
ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr15_-_42840961 0.47 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
leucine rich repeat containing 57
chr12_+_124118366 0.47 ENST00000539994.1
ENST00000538845.1
ENST00000228955.7
ENST00000543341.2
ENST00000536375.1
general transcription factor IIH, polypeptide 3, 34kDa
chr8_-_10697370 0.47 ENST00000314787.3
ENST00000426190.2
ENST00000519088.1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr19_+_19030497 0.47 ENST00000438170.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr8_-_37756972 0.46 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11 family interacting protein 1 (class I)
chr4_-_4543700 0.46 ENST00000505286.1
ENST00000306200.2
syntaxin 18
chr19_+_19030478 0.45 ENST00000247003.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr18_-_268019 0.45 ENST00000261600.6
THO complex 1
chr19_-_16682987 0.44 ENST00000431408.1
ENST00000436553.2
ENST00000595753.1
solute carrier family 35, member E1
chr1_-_145827015 0.44 ENST00000534502.1
ENST00000313835.9
ENST00000454423.3
G protein-coupled receptor 89A
chr15_+_42841008 0.44 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS augmin-like complex, subunit 2
chr2_-_202645612 0.43 ENST00000409632.2
ENST00000410052.1
ENST00000467448.1
amyotrophic lateral sclerosis 2 (juvenile)
chr3_+_196669494 0.43 ENST00000602845.1
NCBP2 antisense RNA 2 (head to head)
chr3_+_113775576 0.42 ENST00000485050.1
ENST00000281273.4
queuine tRNA-ribosyltransferase domain containing 1
chr12_+_64173888 0.42 ENST00000537373.1
transmembrane protein 5
chr1_-_57045228 0.41 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr16_-_3767506 0.41 ENST00000538171.1
TNF receptor-associated protein 1
chr8_-_119124045 0.40 ENST00000378204.2
exostosin glycosyltransferase 1
chr15_-_66790146 0.39 ENST00000316634.5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr11_+_34127142 0.39 ENST00000257829.3
ENST00000531159.2
N-acetyltransferase 10 (GCN5-related)
chr12_-_46384334 0.38 ENST00000369367.3
ENST00000266589.6
ENST00000395453.2
ENST00000395454.2
SR-related CTD-associated factor 11
chr16_-_3767551 0.38 ENST00000246957.5
TNF receptor-associated protein 1
chr9_+_140083099 0.37 ENST00000322310.5
Sjogren syndrome nuclear autoantigen 1
chr1_+_147400506 0.37 ENST00000314163.7
ENST00000468618.2
G protein-coupled receptor 89B
chr10_-_70287172 0.37 ENST00000539557.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr5_-_72861484 0.37 ENST00000296785.3
ankyrin repeat, family A (RFXANK-like), 2
chr9_-_134955246 0.37 ENST00000357028.2
ENST00000474263.1
ENST00000292035.5
mediator complex subunit 27
chr11_-_66112555 0.36 ENST00000425825.2
ENST00000359957.3
breast cancer metastasis suppressor 1
chr2_-_114514181 0.36 ENST00000409342.1
solute carrier family 35, member F5
chr10_-_70287231 0.35 ENST00000609923.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr2_+_190306159 0.35 ENST00000314761.4
WD repeat domain 75
chr6_-_31926208 0.35 ENST00000454913.1
ENST00000436289.2
negative elongation factor complex member E
chr20_+_18488528 0.35 ENST00000377465.1
Sec23 homolog B (S. cerevisiae)
chr8_+_92082424 0.34 ENST00000285420.4
ENST00000404789.3
OTU domain containing 6B
chr1_-_154600421 0.34 ENST00000368471.3
ENST00000292205.5
adenosine deaminase, RNA-specific
chr3_+_48488114 0.33 ENST00000421175.1
ENST00000320211.3
ENST00000346691.4
ENST00000357105.6
ATR interacting protein
chr14_+_32030582 0.33 ENST00000550649.1
ENST00000281081.7
nucleotide binding protein-like
chr20_+_18488137 0.33 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
Sec23 homolog B (S. cerevisiae)
chr19_-_47922373 0.33 ENST00000559524.1
ENST00000557833.1
ENST00000558555.1
ENST00000561293.1
ENST00000441740.2
Meis homeobox 3
chr2_+_114195268 0.33 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
COBW domain containing 2
chr19_-_12807422 0.32 ENST00000380339.3
ENST00000544494.1
ENST00000393261.3
F-box and WD repeat domain containing 9
chr6_-_31926629 0.32 ENST00000375425.5
ENST00000426722.1
ENST00000441998.1
ENST00000444811.2
ENST00000375429.3
negative elongation factor complex member E
chr3_+_48488497 0.32 ENST00000412052.1
ATR interacting protein
chr8_+_145743360 0.32 ENST00000527730.1
ENST00000529022.1
ENST00000292524.1
leucine rich repeat containing 14
chr1_-_53704157 0.32 ENST00000371466.4
ENST00000371470.3
mago-nashi homolog, proliferation-associated (Drosophila)
chr3_-_113775328 0.31 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407
chr5_-_132113063 0.31 ENST00000378719.2
septin 8
chr1_+_36023035 0.31 ENST00000373253.3
neurochondrin
chr9_-_179018 0.31 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
COBW domain containing 1
chr20_+_44420617 0.30 ENST00000449078.1
ENST00000456939.1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr12_+_108079509 0.30 ENST00000412830.3
ENST00000547995.1
PWP1 homolog (S. cerevisiae)
chr1_+_36023370 0.30 ENST00000356090.4
ENST00000373243.2
neurochondrin
chr19_+_18043810 0.29 ENST00000445755.2
coiled-coil domain containing 124
chr3_+_10068095 0.29 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr20_+_44420570 0.29 ENST00000372622.3
deoxynucleotidyltransferase, terminal, interacting protein 1
chr4_+_113558272 0.29 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr7_-_1177874 0.29 ENST00000397098.3
ENST00000357429.6
ENST00000397100.2
ENST00000491163.1
chromosome 7 open reading frame 50
chr21_-_44299626 0.28 ENST00000330317.2
ENST00000398208.2
WD repeat domain 4
chr11_-_62607036 0.28 ENST00000311713.7
ENST00000278856.4
WD repeat domain 74
chr19_-_47922750 0.28 ENST00000331559.5
Meis homeobox 3
chr20_-_31124186 0.28 ENST00000375678.3
chromosome 20 open reading frame 112
chr17_+_8152590 0.28 ENST00000584044.1
ENST00000314666.6
ENST00000545834.1
ENST00000581242.1
phosphoribosylformylglycinamidine synthase
chr9_+_70856899 0.28 ENST00000377342.5
ENST00000478048.1
COBW domain containing 3
chr16_+_2022036 0.28 ENST00000568546.1
transducin (beta)-like 3
chr16_+_19078911 0.27 ENST00000321998.5
coenzyme Q7 homolog, ubiquinone (yeast)
chr16_+_70380732 0.27 ENST00000302243.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
chr12_+_64173583 0.27 ENST00000261234.6
transmembrane protein 5
chr19_+_10362577 0.27 ENST00000592514.1
ENST00000307422.5
ENST00000253099.6
ENST00000590150.1
ENST00000590669.1
mitochondrial ribosomal protein L4
chr9_-_69262509 0.27 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
COBW domain containing 6
chr4_-_100485143 0.26 ENST00000394877.3
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr20_+_3026591 0.26 ENST00000380325.3
mitochondrial ribosomal protein S26
chr14_+_23775971 0.26 ENST00000250405.5
BCL2-like 2
chr14_-_36789865 0.26 ENST00000416007.4
MAP3K12 binding inhibitory protein 1
chr14_+_103995503 0.26 ENST00000389749.4
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr2_-_130939115 0.26 ENST00000441135.1
ENST00000339679.7
ENST00000426662.2
ENST00000443958.2
ENST00000351288.6
ENST00000453750.1
ENST00000452225.2
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chr3_-_9005118 0.26 ENST00000264926.2
RAD18 homolog (S. cerevisiae)
chr6_+_41888926 0.26 ENST00000230340.4
bystin-like
chr19_-_5719860 0.26 ENST00000590729.1
lon peptidase 1, mitochondrial
chr1_+_110527308 0.25 ENST00000369799.5
adenosylhomocysteinase-like 1
chr12_+_7079944 0.25 ENST00000261406.6
EMG1 N1-specific pseudouridine methyltransferase
chr17_-_38083843 0.25 ENST00000304046.2
ENST00000579695.1
ORM1-like 3 (S. cerevisiae)
chr4_+_20702059 0.25 ENST00000444671.2
ENST00000510700.1
ENST00000506745.1
ENST00000514663.1
ENST00000509469.1
ENST00000515339.1
ENST00000513861.1
ENST00000502374.1
ENST00000538990.1
ENST00000511160.1
ENST00000504630.1
ENST00000513590.1
ENST00000514292.1
ENST00000502938.1
ENST00000509625.1
ENST00000505160.1
ENST00000507634.1
ENST00000513459.1
ENST00000511089.1
PARK2 co-regulated-like
chr16_+_70332956 0.25 ENST00000288071.6
ENST00000393657.2
ENST00000355992.3
ENST00000567706.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
Uncharacterized protein
chr2_-_3606206 0.25 ENST00000315212.3
ribonuclease H1
chr12_+_108079664 0.24 ENST00000541166.1
PWP1 homolog (S. cerevisiae)
chr3_-_196295468 0.24 ENST00000332629.5
ENST00000433160.1
WD repeat domain 53
chr11_+_60609537 0.24 ENST00000227520.5
coiled-coil domain containing 86
chr3_-_196295437 0.24 ENST00000429115.1
WD repeat domain 53
chr14_-_36789783 0.24 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MAP3K12 binding inhibitory protein 1
chr8_+_126104076 0.24 ENST00000517532.1
ENST00000287437.3
ENST00000518013.1
ENST00000522563.1
non-SMC element 2, MMS21 homolog (S. cerevisiae)
chr12_+_27932803 0.24 ENST00000381271.2
kelch-like family member 42
chr4_-_146019335 0.24 ENST00000451299.2
ENST00000507656.1
ENST00000309439.5
anaphase promoting complex subunit 10
chr22_-_19132154 0.24 ENST00000252137.6
DiGeorge syndrome critical region gene 14
chr17_+_73663402 0.24 ENST00000355423.3
SAP30 binding protein
chr10_-_119806085 0.24 ENST00000355624.3
RAB11 family interacting protein 2 (class I)
chr16_+_71879861 0.23 ENST00000427980.2
ENST00000568581.1
ataxin 1-like
increased sodium tolerance 1 homolog (yeast)
chr3_+_185303962 0.23 ENST00000296257.5
SUMO1/sentrin/SMT3 specific peptidase 2
chr14_+_103995546 0.23 ENST00000299202.4
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr9_+_70856397 0.23 ENST00000360171.6
COBW domain containing 3
chr1_-_220220000 0.23 ENST00000366923.3
glutamyl-prolyl-tRNA synthetase
chr1_+_213031570 0.23 ENST00000366971.4
feline leukemia virus subgroup C cellular receptor 1
chr17_-_47022140 0.23 ENST00000290330.3
SNF8, ESCRT-II complex subunit
chr10_+_74451883 0.23 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr6_-_32122106 0.22 ENST00000428778.1
proline-rich transmembrane protein 1
chr16_+_68056844 0.22 ENST00000565263.1
dihydrouridine synthase 2
chr11_+_18344106 0.22 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
general transcription factor IIH, polypeptide 1, 62kDa
chr15_+_34394257 0.22 ENST00000397766.2
piggyBac transposable element derived 4
chr2_-_110962544 0.22 ENST00000355301.4
ENST00000445609.2
ENST00000417665.1
ENST00000418527.1
ENST00000316534.4
ENST00000393272.3
nephronophthisis 1 (juvenile)
chr9_-_32573130 0.21 ENST00000350021.2
ENST00000379847.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr4_-_8442438 0.21 ENST00000356406.5
ENST00000413009.2
acyl-CoA oxidase 3, pristanoyl
chr9_-_33001520 0.21 ENST00000463596.1
ENST00000379819.1
ENST00000397172.3
ENST00000379812.5
ENST00000477119.1
ENST00000379813.3
ENST00000379825.2
ENST00000309615.3
ENST00000476858.1
ENST00000473221.1
aprataxin
chr3_-_53290016 0.21 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
transketolase
chr7_+_23145366 0.20 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
kelch-like family member 7
chr17_+_29718642 0.20 ENST00000325874.8
RAB11 family interacting protein 4 (class II)
chr2_-_10830093 0.20 ENST00000381685.5
ENST00000345985.3
ENST00000542668.1
ENST00000538384.1
nucleolar protein 10
chr16_+_68057179 0.20 ENST00000567100.1
ENST00000432752.1
ENST00000569289.1
ENST00000564781.1
dihydrouridine synthase 2
chr4_+_20702030 0.19 ENST00000510051.1
ENST00000503585.1
ENST00000360916.5
ENST00000295290.8
ENST00000514485.1
PARK2 co-regulated-like
chr6_+_37400974 0.19 ENST00000455891.1
ENST00000373451.4
cap methyltransferase 1
chr11_-_57479673 0.19 ENST00000337672.2
ENST00000431606.2
mediator complex subunit 19
chr17_+_73663470 0.19 ENST00000583536.1
SAP30 binding protein
chr3_-_52443799 0.19 ENST00000470173.1
ENST00000296288.5
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr1_-_1510204 0.19 ENST00000291386.3
SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
chr7_+_102036798 0.19 ENST00000397912.3
ENST00000354783.4
PRKR interacting protein 1 (IL11 inducible)
chr16_+_68057153 0.19 ENST00000358896.6
ENST00000568099.2
dihydrouridine synthase 2
chr6_+_20403997 0.19 ENST00000535432.1
E2F transcription factor 3
chr16_+_81348528 0.18 ENST00000568107.2
gigaxonin
chr19_-_54618650 0.18 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr13_-_36920420 0.18 ENST00000438666.2
spastic paraplegia 20 (Troyer syndrome)
chr20_+_3801162 0.18 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
adaptor-related protein complex 5, sigma 1 subunit
chr1_+_186344945 0.18 ENST00000419367.3
ENST00000287859.6
chromosome 1 open reading frame 27
chr4_+_122722466 0.18 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
exosome component 9
chr16_+_70380825 0.18 ENST00000417604.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
chr5_-_132112921 0.17 ENST00000378721.4
ENST00000378701.1
septin 8
chr2_+_96068436 0.17 ENST00000445649.1
ENST00000447036.1
ENST00000233379.4
ENST00000418606.1
fumarylacetoacetate hydrolase domain containing 2A
chr19_-_5720248 0.17 ENST00000360614.3
lon peptidase 1, mitochondrial
chr5_-_132112907 0.17 ENST00000458488.2
septin 8
chr15_-_34394008 0.17 ENST00000527822.1
ENST00000528949.1
ER membrane protein complex subunit 7
chr17_+_33914276 0.17 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr12_-_104532062 0.16 ENST00000240055.3
nuclear transcription factor Y, beta
chr15_-_66790047 0.16 ENST00000566658.1
ENST00000563480.2
ENST00000395589.2
ENST00000307979.7
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr1_+_186344883 0.16 ENST00000367470.3
chromosome 1 open reading frame 27
chr1_-_202896310 0.16 ENST00000367261.3
kelch-like family member 12
chr14_+_104095514 0.16 ENST00000348520.6
ENST00000380038.3
ENST00000389744.4
ENST00000557575.1
ENST00000553286.1
ENST00000347839.6
ENST00000555836.1
ENST00000334553.6
ENST00000246489.7
ENST00000557450.1
ENST00000452929.2
ENST00000554280.1
ENST00000445352.4
kinesin light chain 1
chr3_-_186288097 0.16 ENST00000446782.1
TBCC domain containing 1
chr19_+_7694623 0.16 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
PET100 homolog (S. cerevisiae)
chr12_+_69633407 0.16 ENST00000551516.1
cleavage and polyadenylation specific factor 6, 68kDa
chr1_-_1509931 0.16 ENST00000359060.4
SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
chr15_-_34394119 0.15 ENST00000256545.4
ER membrane protein complex subunit 7
chr19_-_54619006 0.15 ENST00000391759.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr9_-_94877658 0.15 ENST00000262554.2
ENST00000337841.4
serine palmitoyltransferase, long chain base subunit 1
chr4_-_16228120 0.15 ENST00000405303.2
transmembrane anterior posterior transformation 1
chr9_-_139940608 0.15 ENST00000371601.4
neural proliferation, differentiation and control, 1
chr22_-_50946113 0.15 ENST00000216080.5
ENST00000474879.2
ENST00000380796.3
lipase maturation factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.3 0.8 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.3 0.8 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2 1.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 0.9 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.2 1.0 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 1.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 0.8 GO:0009386 translational attenuation(GO:0009386)
0.2 4.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 0.5 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.2 0.5 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 1.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.4 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.4 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.5 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.4 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.5 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.1 0.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.5 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.4 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.1 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.2 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 1.6 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 3.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.6 GO:0021957 corticospinal tract morphogenesis(GO:0021957) anterior commissure morphogenesis(GO:0021960)
0.0 0.5 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 1.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.5 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.7 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0009838 abscission(GO:0009838)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.9 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 1.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0043249 heme transport(GO:0015886) erythrocyte maturation(GO:0043249)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.0 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0 0.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030689 Noc complex(GO:0030689)
0.2 0.8 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 1.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 0.5 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 1.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.7 GO:0032021 NELF complex(GO:0032021)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.3 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.8 GO:0008278 cohesin complex(GO:0008278)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.4 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 1.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.6 1.7 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.3 0.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 0.5 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.2 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.4 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 1.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.5 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.4 GO:0004818 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.1 0.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.9 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 2.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.8 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 1.9 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling