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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CREB3L1_CREB3

Z-value: 0.97

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Transcription factors associated with CREB3L1_CREB3

Gene Symbol Gene ID Gene Info
CREB3L1
ENSG00000157613.6 cAMP responsive element binding protein 3 like 1
CREB3
ENSG00000107175.6 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB3hg19_v2_chr9_+_35732312_357323320.717.9e-05Click!
CREB3L1hg19_v2_chr11_+_46299199_462992330.358.3e-02Click!

Activity profile of CREB3L1_CREB3 motif

Sorted Z-values of CREB3L1_CREB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_116692102 3.70 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr3_-_156272924 2.05 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr2_-_69614373 1.69 ENST00000361060.5
ENST00000357308.4
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr9_+_100818976 1.63 ENST00000210444.5
NANS
N-acetylneuraminic acid synthase
chr11_+_69455855 1.57 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr19_+_38810447 1.49 ENST00000263372.3
KCNK6
potassium channel, subfamily K, member 6
chr6_-_90062543 1.46 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr6_+_31916733 1.43 ENST00000483004.1
CFB
complement factor B
chr22_+_38864041 1.31 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr15_-_40213080 1.26 ENST00000561100.1
GPR176
G protein-coupled receptor 176
chr3_+_133292574 1.22 ENST00000264993.3
CDV3
CDV3 homolog (mouse)
chr5_-_114961673 1.19 ENST00000333314.3
TMED7-TICAM2
TMED7-TICAM2 readthrough
chr7_-_100493744 1.17 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr16_+_19125252 1.14 ENST00000566735.1
ENST00000381440.3
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr5_+_133984462 1.12 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr9_-_101984184 1.12 ENST00000476832.1
ALG2
ALG2, alpha-1,3/1,6-mannosyltransferase
chr11_-_64646086 1.04 ENST00000320631.3
EHD1
EH-domain containing 1
chr12_-_122751002 0.97 ENST00000267199.4
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr11_-_62599505 0.96 ENST00000377897.4
ENST00000394690.1
ENST00000541317.1
ENST00000294179.3
STX5
syntaxin 5
chr5_-_131562935 0.93 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr3_-_118959733 0.93 ENST00000459778.1
ENST00000359213.3
B4GALT4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr11_+_65292538 0.93 ENST00000270176.5
ENST00000525364.1
ENST00000420247.2
ENST00000533862.1
ENST00000279270.6
ENST00000524944.1
SCYL1
SCY1-like 1 (S. cerevisiae)
chr21_+_45138941 0.92 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr12_-_113909877 0.92 ENST00000261731.3
LHX5
LIM homeobox 5
chr9_-_130477912 0.89 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr2_+_27255806 0.88 ENST00000238788.9
ENST00000404032.3
TMEM214
transmembrane protein 214
chr3_-_118959716 0.86 ENST00000467604.1
ENST00000491906.1
ENST00000475803.1
ENST00000479150.1
ENST00000470111.1
ENST00000459820.1
B4GALT4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr7_-_30066233 0.85 ENST00000222803.5
FKBP14
FK506 binding protein 14, 22 kDa
chr11_-_59383617 0.85 ENST00000263847.1
OSBP
oxysterol binding protein
chr5_-_131563501 0.84 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr4_+_25235597 0.81 ENST00000264864.6
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr4_+_56262115 0.81 ENST00000506198.1
ENST00000381334.5
ENST00000542052.1
TMEM165
transmembrane protein 165
chr4_+_40058411 0.80 ENST00000261435.6
ENST00000515550.1
N4BP2
NEDD4 binding protein 2
chr5_+_176730769 0.79 ENST00000303204.4
ENST00000503216.1
PRELID1
PRELI domain containing 1
chr12_+_113376249 0.77 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr11_+_65292884 0.76 ENST00000527009.1
SCYL1
SCY1-like 1 (S. cerevisiae)
chr3_-_150264272 0.76 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr12_+_107349497 0.73 ENST00000548125.1
ENST00000280756.4
C12orf23
chromosome 12 open reading frame 23
chr6_+_138483058 0.73 ENST00000251691.4
KIAA1244
KIAA1244
chr12_-_76953453 0.72 ENST00000549570.1
OSBPL8
oxysterol binding protein-like 8
chr12_-_106641728 0.72 ENST00000378026.4
CKAP4
cytoskeleton-associated protein 4
chr5_-_114961858 0.72 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2
TMED7
TICAM2
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr7_+_6522922 0.71 ENST00000601673.1
FLJ20306
CDNA FLJ20306 fis, clone HEP06881; Putative uncharacterized protein FLJ20306; Uncharacterized protein
chr18_+_56806701 0.68 ENST00000587834.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr14_+_50087468 0.68 ENST00000305386.2
MGAT2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr6_-_101329157 0.68 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr4_-_119757239 0.65 ENST00000280551.6
SEC24D
SEC24 family member D
chr1_+_145575980 0.65 ENST00000393045.2
PIAS3
protein inhibitor of activated STAT, 3
chr1_+_145576007 0.64 ENST00000369298.1
PIAS3
protein inhibitor of activated STAT, 3
chr9_+_114393581 0.63 ENST00000313525.3
DNAJC25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr6_-_101329191 0.60 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr10_-_27444143 0.60 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr5_-_19988339 0.57 ENST00000382275.1
CDH18
cadherin 18, type 2
chr16_+_56642041 0.57 ENST00000245185.5
MT2A
metallothionein 2A
chr16_+_56642489 0.56 ENST00000561491.1
MT2A
metallothionein 2A
chr16_+_57220193 0.55 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
RSPRY1
ring finger and SPRY domain containing 1
chr1_+_26758790 0.54 ENST00000427245.2
ENST00000525682.2
ENST00000236342.7
ENST00000526219.1
ENST00000374185.3
ENST00000360009.2
DHDDS
dehydrodolichyl diphosphate synthase
chr3_-_57583130 0.54 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr7_+_72848092 0.54 ENST00000344575.3
FZD9
frizzled family receptor 9
chr13_+_113951607 0.53 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr17_+_33307503 0.53 ENST00000378526.4
ENST00000585941.1
ENST00000262327.5
ENST00000592690.1
ENST00000585740.1
LIG3
ligase III, DNA, ATP-dependent
chr18_+_76829441 0.52 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr1_-_101360331 0.51 ENST00000416479.1
ENST00000370113.3
EXTL2
exostosin-like glycosyltransferase 2
chr5_-_10761206 0.51 ENST00000432074.2
ENST00000230895.6
DAP
death-associated protein
chr3_-_57583185 0.51 ENST00000463880.1
ARF4
ADP-ribosylation factor 4
chr3_-_107941209 0.50 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr5_-_131132614 0.50 ENST00000307968.7
ENST00000307954.8
FNIP1
folliculin interacting protein 1
chrX_-_8139308 0.50 ENST00000317103.4
VCX2
variable charge, X-linked 2
chr4_+_6202448 0.49 ENST00000508601.1
RP11-586D19.1
RP11-586D19.1
chr11_-_67276100 0.49 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr14_+_78227105 0.48 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chr2_-_47572105 0.47 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
AC073283.4
chr12_-_10766184 0.47 ENST00000539554.1
ENST00000381881.2
ENST00000320756.2
MAGOHB
mago-nashi homolog B (Drosophila)
chr16_-_11836595 0.46 ENST00000356957.3
ENST00000283033.5
TXNDC11
thioredoxin domain containing 11
chr4_+_110736659 0.46 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chr2_+_171785824 0.46 ENST00000452526.2
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr17_-_15466742 0.46 ENST00000584811.1
ENST00000419890.2
TVP23C
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
chr11_+_1891380 0.46 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
LSP1
lymphocyte-specific protein 1
chr19_-_4670345 0.45 ENST00000599630.1
ENST00000262947.3
C19orf10
chromosome 19 open reading frame 10
chr3_-_57583052 0.44 ENST00000496292.1
ENST00000489843.1
ARF4
ADP-ribosylation factor 4
chr1_+_92414952 0.44 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT
bromodomain, testis-specific
chr2_-_33824336 0.44 ENST00000431950.1
ENST00000403368.1
ENST00000441530.2
FAM98A
family with sequence similarity 98, member A
chr10_-_22292675 0.44 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr7_+_39663061 0.44 ENST00000005257.2
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr19_-_40724246 0.43 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr19_-_41196458 0.43 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr1_-_38156153 0.43 ENST00000464085.1
ENST00000486637.1
ENST00000358011.4
ENST00000461359.1
C1orf109
chromosome 1 open reading frame 109
chr5_+_126853301 0.42 ENST00000296666.8
ENST00000442138.2
ENST00000512635.2
PRRC1
proline-rich coiled-coil 1
chr5_-_176730676 0.42 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr1_+_119911425 0.42 ENST00000361035.4
ENST00000325945.3
HAO2
hydroxyacid oxidase 2 (long chain)
chr12_-_53473136 0.42 ENST00000547837.1
ENST00000301463.4
SPRYD3
SPRY domain containing 3
chr2_-_33824382 0.41 ENST00000238823.8
FAM98A
family with sequence similarity 98, member A
chr15_+_81589254 0.41 ENST00000394652.2
IL16
interleukin 16
chr6_-_7313381 0.41 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
SSR1
signal sequence receptor, alpha
chr4_+_165675269 0.41 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr8_+_22423219 0.40 ENST00000523965.1
ENST00000521554.1
SORBS3
sorbin and SH3 domain containing 3
chr10_-_111683308 0.40 ENST00000502935.1
ENST00000322238.8
ENST00000369680.4
XPNPEP1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr3_-_156272872 0.40 ENST00000476217.1
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr19_-_49015050 0.39 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr3_-_107941230 0.39 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr1_-_65432171 0.39 ENST00000342505.4
JAK1
Janus kinase 1
chr8_-_134115118 0.39 ENST00000395352.3
ENST00000338087.5
SLA
Src-like-adaptor
chr10_-_111683183 0.39 ENST00000403138.2
ENST00000369683.1
XPNPEP1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr3_-_113465065 0.38 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr11_-_65686586 0.38 ENST00000438576.2
C11orf68
chromosome 11 open reading frame 68
chr19_+_49458107 0.38 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chrX_-_153237258 0.36 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)
chr12_-_63328817 0.36 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr17_-_7137582 0.36 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr12_-_76953513 0.35 ENST00000547540.1
OSBPL8
oxysterol binding protein-like 8
chr10_+_27444268 0.34 ENST00000375940.4
ENST00000342386.6
MASTL
microtubule associated serine/threonine kinase-like
chr1_+_162531294 0.34 ENST00000367926.4
ENST00000271469.3
UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1
chr7_+_100271446 0.33 ENST00000419828.1
ENST00000427895.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chrX_-_153236819 0.33 ENST00000354233.3
HCFC1
host cell factor C1 (VP16-accessory protein)
chr1_+_11866270 0.33 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr10_+_121410882 0.33 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr10_+_121652204 0.33 ENST00000369075.3
ENST00000543134.1
SEC23IP
SEC23 interacting protein
chr11_+_47430133 0.32 ENST00000531974.1
ENST00000531419.1
ENST00000531865.1
ENST00000362021.4
ENST00000354884.4
SLC39A13
solute carrier family 39 (zinc transporter), member 13
chr3_+_50284321 0.32 ENST00000451956.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr9_+_101984577 0.32 ENST00000223641.4
SEC61B
Sec61 beta subunit
chr14_+_24600484 0.32 ENST00000267426.5
FITM1
fat storage-inducing transmembrane protein 1
chr4_-_111544254 0.32 ENST00000306732.3
PITX2
paired-like homeodomain 2
chr12_-_101801505 0.32 ENST00000539055.1
ENST00000551688.1
ENST00000551671.1
ENST00000261636.8
ARL1
ADP-ribosylation factor-like 1
chr8_+_22423168 0.31 ENST00000518912.1
ENST00000428103.1
SORBS3
sorbin and SH3 domain containing 3
chr6_-_28891709 0.31 ENST00000377194.3
ENST00000377199.3
TRIM27
tripartite motif containing 27
chr5_-_89825328 0.31 ENST00000500869.2
ENST00000315948.6
ENST00000509384.1
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr10_-_90342947 0.31 ENST00000437752.1
ENST00000331772.4
RNLS
renalase, FAD-dependent amine oxidase
chr2_+_192542850 0.30 ENST00000410026.2
NABP1
nucleic acid binding protein 1
chr2_-_202645612 0.30 ENST00000409632.2
ENST00000410052.1
ENST00000467448.1
ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr9_+_126777676 0.30 ENST00000488674.2
LHX2
LIM homeobox 2
chr17_-_61777090 0.30 ENST00000578061.1
LIMD2
LIM domain containing 2
chr15_+_41952591 0.30 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA
MGA, MAX dimerization protein
chr3_-_49395892 0.30 ENST00000419783.1
GPX1
glutathione peroxidase 1
chr19_-_41196534 0.30 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr11_-_65686496 0.29 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr7_+_100271355 0.29 ENST00000436220.1
ENST00000424361.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr20_+_33146510 0.29 ENST00000397709.1
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr17_-_15466850 0.29 ENST00000438826.3
ENST00000225576.3
ENST00000519970.1
ENST00000518321.1
ENST00000428082.2
ENST00000522212.2
TVP23C
TVP23C-CDRT4
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TVP23C-CDRT4 readthrough
chr2_+_219745020 0.28 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr7_+_116593953 0.28 ENST00000397750.3
ST7-OT4
ST7 overlapping transcript 4
chr3_+_113465866 0.28 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr3_-_47823298 0.28 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chrX_-_6453159 0.28 ENST00000381089.3
ENST00000398729.1
VCX3A
variable charge, X-linked 3A
chr2_-_68479614 0.28 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr14_-_35344093 0.27 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr11_+_65686802 0.27 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr17_+_57642886 0.27 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr17_-_73401567 0.27 ENST00000392562.1
GRB2
growth factor receptor-bound protein 2
chr12_+_49372251 0.27 ENST00000293549.3
WNT1
wingless-type MMTV integration site family, member 1
chr3_-_119182523 0.27 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr20_-_62738524 0.26 ENST00000369768.1
NPBWR2
neuropeptides B/W receptor 2
chrX_+_8433376 0.26 ENST00000440654.2
ENST00000381029.4
VCX3B
variable charge, X-linked 3B
chr6_+_26020672 0.26 ENST00000357647.3
HIST1H3A
histone cluster 1, H3a
chr6_-_135375921 0.26 ENST00000367820.2
ENST00000314674.3
ENST00000524715.1
ENST00000415177.2
ENST00000367826.2
HBS1L
HBS1-like (S. cerevisiae)
chr11_+_32112431 0.26 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr5_-_131132658 0.25 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr12_-_76953573 0.25 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
OSBPL8
oxysterol binding protein-like 8
chr3_+_35721106 0.25 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr6_-_137815524 0.25 ENST00000367734.2
OLIG3
oligodendrocyte transcription factor 3
chrX_+_16141667 0.25 ENST00000380289.2
GRPR
gastrin-releasing peptide receptor
chr11_-_14521379 0.24 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
COPB1
coatomer protein complex, subunit beta 1
chr11_-_118927816 0.24 ENST00000534233.1
ENST00000532752.1
ENST00000525859.1
ENST00000404233.3
ENST00000532421.1
ENST00000543287.1
ENST00000527310.2
ENST00000529972.1
HYOU1
hypoxia up-regulated 1
chr3_+_121554046 0.24 ENST00000273668.2
ENST00000451944.2
EAF2
ELL associated factor 2
chr21_+_44313375 0.24 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr1_+_200638629 0.24 ENST00000568695.1
RP11-92G12.3
RP11-92G12.3
chr8_-_71519889 0.23 ENST00000521425.1
TRAM1
translocation associated membrane protein 1
chr13_-_36920420 0.23 ENST00000438666.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr6_-_119399895 0.23 ENST00000338891.7
FAM184A
family with sequence similarity 184, member A
chr20_+_23331373 0.23 ENST00000254998.2
NXT1
NTF2-like export factor 1
chr2_-_99917639 0.23 ENST00000308528.4
LYG1
lysozyme G-like 1
chr14_+_103995503 0.23 ENST00000389749.4
TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr9_-_136242956 0.23 ENST00000371989.3
ENST00000485435.2
SURF4
surfeit 4
chr2_+_183580954 0.23 ENST00000264065.7
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr1_-_241520525 0.22 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr11_+_64889773 0.22 ENST00000534078.1
ENST00000526171.1
ENST00000279242.2
ENST00000531705.1
ENST00000533943.1
MRPL49
mitochondrial ribosomal protein L49
chr15_+_72947079 0.22 ENST00000421285.3
GOLGA6B
golgin A6 family, member B
chr11_+_65819802 0.22 ENST00000528302.1
ENST00000322535.6
ENST00000524627.1
ENST00000533595.1
ENST00000530322.1
SF3B2
splicing factor 3b, subunit 2, 145kDa
chr1_-_42921915 0.22 ENST00000372565.3
ENST00000433602.2
ZMYND12
zinc finger, MYND-type containing 12
chr14_+_103995546 0.22 ENST00000299202.4
TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr22_+_39916558 0.22 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr20_-_1306391 0.22 ENST00000339987.3
SDCBP2
syndecan binding protein (syntenin) 2
chr16_-_66959429 0.22 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr11_-_102576537 0.22 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr5_+_94890840 0.22 ENST00000504763.1
ARSK
arylsulfatase family, member K
chr1_-_42800860 0.22 ENST00000445886.1
ENST00000361346.1
ENST00000361776.1
FOXJ3
forkhead box J3
chr3_-_49395705 0.22 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr16_+_84209738 0.22 ENST00000564928.1
DNAAF1
dynein, axonemal, assembly factor 1
chr20_-_1306351 0.21 ENST00000381812.1
SDCBP2
syndecan binding protein (syntenin) 2
chrX_+_8432871 0.21 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
VCX3B
variable charge, X-linked 3B
chr16_-_2059748 0.21 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr5_+_149340282 0.21 ENST00000286298.4
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr3_-_194119083 0.21 ENST00000401815.1
GP5
glycoprotein V (platelet)
chr1_-_200638964 0.21 ENST00000367348.3
ENST00000447706.2
ENST00000331314.6
DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr22_-_20850070 0.21 ENST00000440659.2
ENST00000458248.1
ENST00000443285.1
ENST00000444967.1
ENST00000451553.1
ENST00000431430.1
KLHL22
kelch-like family member 22
chr1_-_42801540 0.21 ENST00000372573.1
FOXJ3
forkhead box J3
chr4_+_165675197 0.21 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr11_+_65686728 0.21 ENST00000312515.2
ENST00000525501.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_-_46088068 0.20 ENST00000263275.4
ENST00000323060.3
OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr1_-_202896310 0.20 ENST00000367261.3
KLHL12
kelch-like family member 12
chr6_+_42531798 0.20 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.3 0.9 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.3 1.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 0.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.7 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.2 1.1 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2 0.5 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.2 0.5 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.2 0.5 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.2 0.7 GO:0019046 release from viral latency(GO:0019046)
0.2 1.8 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 0.8 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 2.0 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 0.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 0.6 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 1.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 1.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.3 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.1 1.6 GO:0070141 response to UV-A(GO:0070141)
0.1 1.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 1.5 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.5 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.5 GO:1901859 base-excision repair, DNA ligation(GO:0006288) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.1 3.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.9 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 1.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.0 GO:0090166 Golgi disassembly(GO:0090166)
0.1 0.8 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.1 1.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.3 GO:0036090 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.3 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.5 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1 1.6 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.1 0.3 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 1.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.3 GO:0061054 Spemann organizer formation(GO:0060061) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.1 1.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.6 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.5 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 1.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 0.2 GO:1990144 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.1 0.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.3 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.8 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.2 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.1 0.9 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 1.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 1.9 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.8 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.9 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.6 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.4 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.4 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.7 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.6 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.1 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.1 GO:0090024 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.3 GO:1902074 response to salt(GO:1902074)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 2.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.3 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.3 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.3 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.0 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.0 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.0 GO:0002188 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 2.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 2.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.5 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 1.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.5 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.1 0.7 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.7 GO:0097413 Lewy body(GO:0097413)
0.1 0.9 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.9 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.7 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:1990032 climbing fiber(GO:0044301) parallel fiber(GO:1990032)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0019012 virion(GO:0019012) virion part(GO:0044423)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.0 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 1.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.9 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.3 0.9 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.3 1.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.3 1.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 1.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 0.8 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 0.5 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 1.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 0.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 1.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.5 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.5 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 1.6 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.1 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.7 GO:0008483 transaminase activity(GO:0008483)
0.1 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 1.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 1.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.9 GO:0070513 death domain binding(GO:0070513)
0.0 1.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 1.4 GO:0001848 complement binding(GO:0001848)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.0 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.3 ST ADRENERGIC Adrenergic Pathway
0.0 1.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.7 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 0.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 4.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 2.7 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 2.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 2.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway