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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CREB3L2

Z-value: 1.19

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Transcription factors associated with CREB3L2

Gene Symbol Gene ID Gene Info
CREB3L2
ENSG00000182158.10 cAMP responsive element binding protein 3 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB3L2hg19_v2_chr7_-_137686791_1376868210.252.3e-01Click!

Activity profile of CREB3L2 motif

Sorted Z-values of CREB3L2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_89182156 7.47 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182178 7.31 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89181974 6.33 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_+_32811885 3.87 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr1_-_11120057 2.84 ENST00000376957.2
SRM
spermidine synthase
chr15_-_40213080 2.37 ENST00000561100.1
GPR176
G protein-coupled receptor 176
chr20_-_22559211 2.20 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr6_-_32811771 2.17 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr3_-_123603137 2.11 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK
myosin light chain kinase
chr6_+_32811861 2.09 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr14_+_93799556 1.93 ENST00000256339.4
UNC79
unc-79 homolog (C. elegans)
chr2_-_69614373 1.83 ENST00000361060.5
ENST00000357308.4
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr9_-_130477912 1.83 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr20_+_61584026 1.82 ENST00000370351.4
ENST00000370349.3
SLC17A9
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr5_-_169816638 1.71 ENST00000521859.1
ENST00000274629.4
KCNMB1
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr21_-_18985230 1.69 ENST00000457956.1
ENST00000348354.6
BTG3
BTG family, member 3
chr18_+_56807096 1.69 ENST00000588875.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr21_-_18985158 1.67 ENST00000339775.6
BTG3
BTG family, member 3
chr5_+_176730769 1.62 ENST00000303204.4
ENST00000503216.1
PRELID1
PRELI domain containing 1
chr1_+_101361782 1.57 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr18_+_56806701 1.53 ENST00000587834.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr1_-_111746966 1.53 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr10_+_103892787 1.47 ENST00000278070.2
ENST00000413464.2
PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr8_+_22224760 1.44 ENST00000359741.5
ENST00000520644.1
ENST00000240095.6
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr1_-_31712401 1.41 ENST00000373736.2
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr2_+_74425689 1.36 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr17_-_74722536 1.27 ENST00000585429.1
JMJD6
jumonji domain containing 6
chr10_-_71993176 1.26 ENST00000373232.3
PPA1
pyrophosphatase (inorganic) 1
chr2_-_10588630 1.24 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr1_-_145039949 1.24 ENST00000313382.9
PDE4DIP
phosphodiesterase 4D interacting protein
chr5_+_34656569 1.21 ENST00000428746.2
RAI14
retinoic acid induced 14
chr9_-_136203235 1.19 ENST00000372022.4
SURF6
surfeit 6
chr17_-_74722672 1.15 ENST00000397625.4
ENST00000445478.2
JMJD6
jumonji domain containing 6
chr5_+_34656331 1.15 ENST00000265109.3
RAI14
retinoic acid induced 14
chr11_-_6502534 1.13 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ARFIP2
ADP-ribosylation factor interacting protein 2
chr8_+_22102611 1.13 ENST00000306433.4
POLR3D
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr8_+_22225041 1.09 ENST00000289952.5
ENST00000524285.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr7_-_8302298 1.08 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa
chr3_+_94657086 1.08 ENST00000463200.1
LINC00879
long intergenic non-protein coding RNA 879
chr8_+_22102626 1.07 ENST00000519237.1
ENST00000397802.4
POLR3D
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr10_+_70715884 1.07 ENST00000354185.4
DDX21
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr11_-_6502580 1.07 ENST00000423813.2
ENST00000396777.3
ARFIP2
ADP-ribosylation factor interacting protein 2
chr19_-_4670345 1.06 ENST00000599630.1
ENST00000262947.3
C19orf10
chromosome 19 open reading frame 10
chr12_-_53473136 1.05 ENST00000547837.1
ENST00000301463.4
SPRYD3
SPRY domain containing 3
chr8_+_82192501 1.04 ENST00000297258.6
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr16_+_57220193 1.03 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
RSPRY1
ring finger and SPRY domain containing 1
chr3_+_94657118 1.00 ENST00000466089.1
ENST00000470465.1
LINC00879
long intergenic non-protein coding RNA 879
chr3_+_133292759 0.97 ENST00000431519.2
CDV3
CDV3 homolog (mouse)
chr1_+_92414952 0.97 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT
bromodomain, testis-specific
chr22_-_18257249 0.97 ENST00000399765.1
ENST00000399767.1
ENST00000399774.3
BID
BH3 interacting domain death agonist
chr5_-_176730676 0.96 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr22_-_18257178 0.95 ENST00000342111.5
BID
BH3 interacting domain death agonist
chr17_+_33307503 0.93 ENST00000378526.4
ENST00000585941.1
ENST00000262327.5
ENST00000592690.1
ENST00000585740.1
LIG3
ligase III, DNA, ATP-dependent
chr15_+_59063478 0.93 ENST00000559228.1
ENST00000450403.2
FAM63B
family with sequence similarity 63, member B
chr19_-_47290535 0.92 ENST00000412532.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr1_+_180123969 0.92 ENST00000367602.3
ENST00000367600.5
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr22_-_43253189 0.91 ENST00000437119.2
ENST00000429508.2
ENST00000454099.1
ENST00000263245.5
ARFGAP3
ADP-ribosylation factor GTPase activating protein 3
chr17_-_30185971 0.90 ENST00000378634.2
COPRS
coordinator of PRMT5, differentiation stimulator
chr17_-_30185946 0.85 ENST00000579741.1
COPRS
coordinator of PRMT5, differentiation stimulator
chr8_+_99129513 0.85 ENST00000522319.1
ENST00000401707.2
POP1
processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
chr1_+_44444865 0.84 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr22_-_18256742 0.84 ENST00000317361.7
BID
BH3 interacting domain death agonist
chr6_-_28891709 0.83 ENST00000377194.3
ENST00000377199.3
TRIM27
tripartite motif containing 27
chr1_-_231004220 0.82 ENST00000366663.5
C1orf198
chromosome 1 open reading frame 198
chr18_+_9708162 0.81 ENST00000578921.1
RAB31
RAB31, member RAS oncogene family
chr5_+_133984462 0.79 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr4_+_40058411 0.79 ENST00000261435.6
ENST00000515550.1
N4BP2
NEDD4 binding protein 2
chr6_-_43197189 0.79 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr17_-_30186328 0.78 ENST00000302362.6
COPRS
coordinator of PRMT5, differentiation stimulator
chr12_+_6833237 0.77 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COPS7A
COP9 signalosome subunit 7A
chr1_+_154193325 0.76 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L
ubiquitin associated protein 2-like
chr19_-_40854281 0.75 ENST00000392035.2
C19orf47
chromosome 19 open reading frame 47
chr1_+_11866270 0.75 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr3_-_155572164 0.73 ENST00000392845.3
ENST00000359479.3
SLC33A1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr12_+_6833437 0.73 ENST00000534947.1
ENST00000541866.1
ENST00000534877.1
ENST00000538753.1
COPS7A
COP9 signalosome subunit 7A
chr11_+_6502675 0.73 ENST00000254616.6
ENST00000530751.1
TIMM10B
translocase of inner mitochondrial membrane 10 homolog B (yeast)
chr8_-_134584152 0.72 ENST00000521180.1
ENST00000517668.1
ENST00000319914.5
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr22_+_39916558 0.71 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr1_+_44445549 0.71 ENST00000356836.6
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr11_+_65479702 0.70 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5
K(lysine) acetyltransferase 5
chrX_+_128913906 0.69 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr7_-_6523688 0.68 ENST00000490996.1
KDELR2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr12_-_76953453 0.68 ENST00000549570.1
OSBPL8
oxysterol binding protein-like 8
chr9_+_37079888 0.67 ENST00000429493.1
ENST00000593237.1
ENST00000588557.1
ENST00000430809.1
ENST00000592157.1
RP11-220I1.1
RP11-220I1.1
chr20_-_44519839 0.65 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr7_+_72848092 0.65 ENST00000344575.3
FZD9
frizzled family receptor 9
chr19_+_49458107 0.64 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chr16_+_19125252 0.64 ENST00000566735.1
ENST00000381440.3
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr2_-_47572105 0.64 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
AC073283.4
chr15_+_41913690 0.63 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr3_+_122785895 0.63 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr6_+_13615554 0.62 ENST00000451315.2
NOL7
nucleolar protein 7, 27kDa
chr16_+_66914264 0.62 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr5_+_112196919 0.61 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
SRP19
signal recognition particle 19kDa
chr10_+_89419370 0.61 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr17_+_7255208 0.60 ENST00000333751.3
KCTD11
potassium channel tetramerization domain containing 11
chr14_+_105155925 0.59 ENST00000330634.7
ENST00000398337.4
ENST00000392634.4
INF2
inverted formin, FH2 and WH2 domain containing
chr7_+_148844516 0.59 ENST00000420008.2
ENST00000475153.1
ZNF398
zinc finger protein 398
chr1_-_241520525 0.59 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr1_-_42921915 0.58 ENST00000372565.3
ENST00000433602.2
ZMYND12
zinc finger, MYND-type containing 12
chrX_-_48433275 0.57 ENST00000376775.2
AC115618.1
Uncharacterized protein; cDNA FLJ26048 fis, clone PRS02384
chr11_+_32112431 0.54 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr2_-_128643496 0.53 ENST00000272647.5
AMMECR1L
AMMECR1-like
chr22_-_50523760 0.53 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_+_145575980 0.52 ENST00000393045.2
PIAS3
protein inhibitor of activated STAT, 3
chr16_+_70613770 0.52 ENST00000429149.2
ENST00000563721.2
IL34
interleukin 34
chr22_+_38864041 0.51 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr4_-_83812248 0.51 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
SEC31A
SEC31 homolog A (S. cerevisiae)
chr2_+_171785824 0.51 ENST00000452526.2
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr1_+_145576007 0.51 ENST00000369298.1
PIAS3
protein inhibitor of activated STAT, 3
chr1_-_154193009 0.51 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43
chromosome 1 open reading frame 43
chrX_+_131157290 0.50 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr2_+_131100710 0.49 ENST00000452955.1
IMP4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr10_-_71930222 0.49 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1A
SAR1 homolog A (S. cerevisiae)
chr16_+_4897632 0.49 ENST00000262376.6
UBN1
ubinuclein 1
chr4_-_83812402 0.49 ENST00000395310.2
SEC31A
SEC31 homolog A (S. cerevisiae)
chr5_-_114880533 0.48 ENST00000274457.3
FEM1C
fem-1 homolog c (C. elegans)
chr19_+_10812108 0.48 ENST00000250237.5
ENST00000592254.1
QTRT1
queuine tRNA-ribosyltransferase 1
chr18_+_158513 0.47 ENST00000400266.3
ENST00000580410.1
ENST00000383589.2
ENST00000261601.7
USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr17_+_72270429 0.46 ENST00000311014.6
DNAI2
dynein, axonemal, intermediate chain 2
chr6_-_136871957 0.46 ENST00000354570.3
MAP7
microtubule-associated protein 7
chrX_+_153686614 0.46 ENST00000369682.3
PLXNA3
plexin A3
chr22_-_35627045 0.44 ENST00000423311.1
CTA-714B7.5
CTA-714B7.5
chr1_-_154193091 0.44 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43
chromosome 1 open reading frame 43
chr8_-_134584092 0.44 ENST00000522652.1
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr2_-_73340146 0.43 ENST00000258098.6
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chrX_+_131157322 0.43 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chr9_+_130565487 0.43 ENST00000373225.3
ENST00000431857.1
FPGS
folylpolyglutamate synthase
chr9_+_130565147 0.42 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
FPGS
folylpolyglutamate synthase
chr1_-_1167411 0.42 ENST00000263741.7
SDF4
stromal cell derived factor 4
chr15_-_98417780 0.42 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr3_+_184098065 0.41 ENST00000348986.3
CHRD
chordin
chr10_-_22292675 0.41 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr16_-_28074822 0.41 ENST00000395724.3
ENST00000380898.2
ENST00000447459.2
GSG1L
GSG1-like
chr20_+_2821340 0.41 ENST00000380445.3
ENST00000380469.3
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr5_-_1799932 0.40 ENST00000382647.7
ENST00000505059.2
MRPL36
mitochondrial ribosomal protein L36
chr15_-_90645679 0.40 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
IDH2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr5_+_178368186 0.40 ENST00000320129.3
ENST00000519564.1
ZNF454
zinc finger protein 454
chr16_-_21314360 0.39 ENST00000219599.3
ENST00000576703.1
CRYM
crystallin, mu
chr20_+_61436146 0.39 ENST00000290291.6
OGFR
opioid growth factor receptor
chr5_-_138725594 0.39 ENST00000302125.8
MZB1
marginal zone B and B1 cell-specific protein
chr3_+_51428704 0.39 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chr12_+_122064673 0.38 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr5_-_1799965 0.38 ENST00000508987.1
MRPL36
mitochondrial ribosomal protein L36
chr19_-_47164386 0.37 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr5_-_138725560 0.37 ENST00000412103.2
ENST00000457570.2
MZB1
marginal zone B and B1 cell-specific protein
chr21_+_45875354 0.37 ENST00000291592.4
LRRC3
leucine rich repeat containing 3
chr6_+_158733692 0.37 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr5_-_158636512 0.37 ENST00000424310.2
RNF145
ring finger protein 145
chr12_+_57624119 0.35 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr9_+_92219919 0.35 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr2_+_203130439 0.35 ENST00000264279.5
NOP58
NOP58 ribonucleoprotein
chr8_+_9009296 0.35 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr17_-_48450534 0.35 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
MRPL27
mitochondrial ribosomal protein L27
chrX_+_105937068 0.34 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr2_-_85108363 0.34 ENST00000335459.5
TRABD2A
TraB domain containing 2A
chr1_-_27240455 0.34 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr9_+_130478345 0.34 ENST00000373289.3
ENST00000393748.4
TTC16
tetratricopeptide repeat domain 16
chr20_+_25228669 0.33 ENST00000216962.4
PYGB
phosphorylase, glycogen; brain
chr3_-_57583130 0.33 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr3_+_188889737 0.33 ENST00000345063.3
TPRG1
tumor protein p63 regulated 1
chr12_+_131356582 0.32 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
RAN
RAN, member RAS oncogene family
chr5_+_152870106 0.32 ENST00000285900.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr9_-_113800341 0.32 ENST00000358883.4
LPAR1
lysophosphatidic acid receptor 1
chr20_-_33413416 0.32 ENST00000359003.2
NCOA6
nuclear receptor coactivator 6
chr9_+_37120536 0.31 ENST00000336755.5
ENST00000534928.1
ENST00000322831.6
ZCCHC7
zinc finger, CCHC domain containing 7
chr8_-_143696833 0.31 ENST00000356613.2
ARC
activity-regulated cytoskeleton-associated protein
chr15_+_62359175 0.30 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chr5_-_131132614 0.30 ENST00000307968.7
ENST00000307954.8
FNIP1
folliculin interacting protein 1
chr1_+_11866207 0.30 ENST00000312413.6
ENST00000346436.6
CLCN6
chloride channel, voltage-sensitive 6
chr21_+_44394742 0.29 ENST00000432907.2
PKNOX1
PBX/knotted 1 homeobox 1
chr2_-_65357225 0.29 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A
RAB1A, member RAS oncogene family
chr20_-_44993012 0.29 ENST00000372229.1
ENST00000372230.5
ENST00000543605.1
ENST00000243896.2
ENST00000317734.8
SLC35C2
solute carrier family 35 (GDP-fucose transporter), member C2
chr22_-_43411106 0.29 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr5_-_150537279 0.28 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
ANXA6
annexin A6
chr11_+_537494 0.28 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr4_+_119199864 0.28 ENST00000602414.1
ENST00000602520.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr5_+_125935960 0.28 ENST00000297540.4
PHAX
phosphorylated adaptor for RNA export
chr19_-_13030071 0.27 ENST00000293695.7
SYCE2
synaptonemal complex central element protein 2
chr12_-_49318715 0.26 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr9_-_136242956 0.26 ENST00000371989.3
ENST00000485435.2
SURF4
surfeit 4
chr1_+_92414928 0.26 ENST00000362005.3
ENST00000370389.2
ENST00000399546.2
ENST00000423434.1
ENST00000394530.3
ENST00000440509.1
BRDT
bromodomain, testis-specific
chr2_-_85108164 0.25 ENST00000409520.2
TRABD2A
TraB domain containing 2A
chr6_-_36953833 0.25 ENST00000538808.1
ENST00000460219.1
ENST00000373616.5
ENST00000373627.5
MTCH1
mitochondrial carrier 1
chr1_-_153940097 0.25 ENST00000413622.1
ENST00000310483.6
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr10_+_64893039 0.24 ENST00000277746.6
ENST00000435510.2
NRBF2
nuclear receptor binding factor 2
chr11_+_67776012 0.24 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr12_+_57623869 0.24 ENST00000414700.3
ENST00000557703.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_-_231376836 0.24 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr11_-_118972575 0.24 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr1_-_114447412 0.24 ENST00000369567.1
ENST00000369566.3
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr2_+_172543919 0.24 ENST00000452242.1
ENST00000340296.4
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr3_-_57583052 0.24 ENST00000496292.1
ENST00000489843.1
ARF4
ADP-ribosylation factor 4
chr5_-_131132658 0.24 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr12_-_76953573 0.24 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
OSBPL8
oxysterol binding protein-like 8
chr9_+_124461603 0.23 ENST00000373782.3
DAB2IP
DAB2 interacting protein
chr8_+_56014949 0.23 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr7_+_23749767 0.23 ENST00000355870.3
STK31
serine/threonine kinase 31
chr7_+_150929550 0.23 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
CHPF2
chondroitin polymerizing factor 2
chr19_-_2783363 0.23 ENST00000221566.2
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 21.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.6 1.7 GO:1903413 cellular response to bile acid(GO:1903413)
0.4 1.2 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.4 2.8 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.3 1.3 GO:0071344 diphosphate metabolic process(GO:0071344)
0.3 1.2 GO:0009446 putrescine biosynthetic process(GO:0009446) putrescine biosynthetic process from ornithine(GO:0033387)
0.3 2.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.3 1.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.3 0.8 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3 2.8 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.2 0.7 GO:1990737 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2 2.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.9 GO:0090296 base-excision repair, DNA ligation(GO:0006288) regulation of mitochondrial DNA replication(GO:0090296) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.2 0.7 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 1.6 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 2.5 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.2 0.9 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 0.6 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.2 0.2 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.2 0.6 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.2 0.6 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.2 0.8 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.2 2.5 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.2 0.8 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 1.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.2 0.6 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.0 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.4 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.4 GO:0035565 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.1 1.8 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.8 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 2.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.8 GO:0016078 tRNA catabolic process(GO:0016078)
0.1 3.2 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 1.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 1.9 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 1.0 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.7 GO:0051182 coenzyme transport(GO:0051182)
0.1 1.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.4 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.1 2.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 1.5 GO:0000338 protein deneddylation(GO:0000338)
0.1 1.0 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.3 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 0.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.2 GO:0072061 hexitol metabolic process(GO:0006059) inner medullary collecting duct development(GO:0072061)
0.1 0.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.3 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 6.0 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.1 0.2 GO:0043000 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.8 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.7 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 1.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.7 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 2.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:0021860 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 2.0 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.8 GO:0072584 caveolin-mediated endocytosis(GO:0072584)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 1.8 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.1 GO:0002188 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0 0.5 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.8 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 1.0 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.4 GO:0006554 lysine catabolic process(GO:0006554) thyroid hormone transport(GO:0070327)
0.0 0.9 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 1.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.4 GO:0009650 UV protection(GO:0009650)
0.0 1.5 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.8 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 1.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.2 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 1.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 3.2 GO:0005787 signal peptidase complex(GO:0005787)
0.3 1.2 GO:0001652 granular component(GO:0001652)
0.3 21.7 GO:0015030 Cajal body(GO:0015030)
0.1 1.0 GO:0070552 BRISC complex(GO:0070552)
0.1 0.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.7 GO:1990037 Lewy body core(GO:1990037)
0.1 2.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.3 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.1 2.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.1 0.3 GO:0044308 axonal spine(GO:0044308)
0.1 0.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 2.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 3.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 3.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0030897 HOPS complex(GO:0030897)
0.0 2.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0032059 bleb(GO:0032059)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.6 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.0 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 21.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.9 2.8 GO:0004766 spermidine synthase activity(GO:0004766)
0.5 2.4 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.5 1.4 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.4 1.6 GO:0004461 lactose synthase activity(GO:0004461)
0.3 1.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.3 1.8 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.3 2.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.3 1.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 0.9 GO:0005046 KDEL sequence binding(GO:0005046)
0.2 2.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.6 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.8 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 6.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 0.9 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 0.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 0.5 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 1.0 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.9 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.5 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.7 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.3 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 3.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.9 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 2.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 1.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 2.8 GO:0005123 death receptor binding(GO:0005123)
0.1 1.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 1.8 GO:0008483 transaminase activity(GO:0008483)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.6 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 1.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 1.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.3 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.2 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 2.5 GO:0042393 histone binding(GO:0042393)
0.0 1.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 2.2 PID ARF 3PATHWAY Arf1 pathway
0.0 2.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 3.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 23.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 3.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 3.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.9 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 3.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA