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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CREB5_CREM_JUNB

Z-value: 1.02

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Transcription factors associated with CREB5_CREM_JUNB

Gene Symbol Gene ID Gene Info
CREB5
ENSG00000146592.12 cAMP responsive element binding protein 5
CREM
ENSG00000095794.15 cAMP responsive element modulator
JUNB
ENSG00000171223.4 JunB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREMhg19_v2_chr10_+_35416090_354161380.681.7e-04Click!
JUNBhg19_v2_chr19_+_12902289_129023100.281.7e-01Click!
CREB5hg19_v2_chr7_+_28452130_28452154-0.213.1e-01Click!

Activity profile of CREB5_CREM_JUNB motif

Sorted Z-values of CREB5_CREM_JUNB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_35484053 5.68 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
CREM
cAMP responsive element modulator
chr10_+_35484793 5.17 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr1_+_203274639 3.44 ENST00000290551.4
BTG2
BTG family, member 2
chr7_-_129592471 3.25 ENST00000473814.2
ENST00000490974.1
UBE2H
ubiquitin-conjugating enzyme E2H
chr5_+_112849373 2.78 ENST00000161863.4
ENST00000515883.1
YTHDC2
YTH domain containing 2
chr11_+_12695944 2.77 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr7_-_129592700 2.60 ENST00000472396.1
ENST00000355621.3
UBE2H
ubiquitin-conjugating enzyme E2H
chr12_+_100660909 2.04 ENST00000549687.1
SCYL2
SCY1-like 2 (S. cerevisiae)
chr21_-_35899113 2.01 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr19_+_45971246 1.98 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr16_-_4588469 1.69 ENST00000588381.1
ENST00000563332.2
CDIP1
cell death-inducing p53 target 1
chr5_-_172198190 1.66 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr5_+_32174483 1.62 ENST00000606994.1
CTD-2186M15.3
CTD-2186M15.3
chr16_-_4588822 1.59 ENST00000564828.1
CDIP1
cell death-inducing p53 target 1
chr16_-_4588762 1.58 ENST00000562334.1
ENST00000562579.1
ENST00000567695.1
ENST00000563507.1
CDIP1
cell death-inducing p53 target 1
chr3_+_8543393 1.55 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr13_-_101327028 1.53 ENST00000328767.5
ENST00000342624.5
ENST00000376234.3
ENST00000423847.1
TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr8_+_98788057 1.48 ENST00000517924.1
LAPTM4B
lysosomal protein transmembrane 4 beta
chr1_-_47184745 1.45 ENST00000544071.1
EFCAB14
EF-hand calcium binding domain 14
chr14_+_63671105 1.40 ENST00000316754.3
RHOJ
ras homolog family member J
chr8_+_98788003 1.39 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr19_+_8455200 1.36 ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr21_-_44846999 1.32 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr11_-_82782952 1.31 ENST00000534141.1
RAB30
RAB30, member RAS oncogene family
chr20_-_39317868 1.30 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr7_-_142232071 1.28 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr22_+_25003568 1.23 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr2_-_216300784 1.21 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr22_+_41075277 1.20 ENST00000381433.2
MCHR1
melanin-concentrating hormone receptor 1
chrX_+_152240819 1.19 ENST00000421798.3
ENST00000535416.1
PNMA6C
PNMA6A
paraneoplastic Ma antigen family member 6C
paraneoplastic Ma antigen family member 6A
chr19_+_49375649 1.16 ENST00000200453.5
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr2_+_33172012 1.16 ENST00000404816.2
LTBP1
latent transforming growth factor beta binding protein 1
chr4_-_116034979 1.13 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr1_-_209979465 1.12 ENST00000542854.1
IRF6
interferon regulatory factor 6
chr6_-_91006627 1.11 ENST00000537989.1
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chrX_+_48398053 1.11 ENST00000537536.1
ENST00000418627.1
TBC1D25
TBC1 domain family, member 25
chr21_+_17443434 1.09 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr6_-_70506963 1.09 ENST00000370577.3
LMBRD1
LMBR1 domain containing 1
chr20_+_10199468 1.08 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr12_+_10365404 1.07 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr2_-_157189180 1.07 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr9_+_116298778 1.06 ENST00000462143.1
RGS3
regulator of G-protein signaling 3
chr2_+_33172221 1.06 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr1_-_47184723 1.04 ENST00000371933.3
EFCAB14
EF-hand calcium binding domain 14
chr4_+_1873100 1.03 ENST00000508803.1
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr10_-_116444371 1.02 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr3_+_8543561 1.01 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr1_-_209979375 1.00 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr6_-_91006461 0.99 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chrX_+_152338301 0.99 ENST00000453825.2
PNMA6A
paraneoplastic Ma antigen family member 6A
chr3_-_64211112 0.99 ENST00000295902.6
PRICKLE2
prickle homolog 2 (Drosophila)
chr21_-_43430440 0.98 ENST00000398505.3
ENST00000310826.5
ENST00000449949.1
ENST00000398499.1
ENST00000398497.2
ENST00000398511.3
ZBTB21
zinc finger and BTB domain containing 21
chr13_-_29069232 0.96 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1
fms-related tyrosine kinase 1
chr17_+_66509019 0.96 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr3_+_141457105 0.96 ENST00000480908.1
ENST00000393000.3
RNF7
ring finger protein 7
chr12_-_6772303 0.95 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4
inhibitor of growth family, member 4
chr6_+_32939964 0.94 ENST00000607833.1
BRD2
bromodomain containing 2
chr3_+_141457030 0.92 ENST00000273480.3
RNF7
ring finger protein 7
chr10_+_35456444 0.91 ENST00000361599.4
CREM
cAMP responsive element modulator
chr1_+_66797687 0.89 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_66059339 0.89 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr8_-_10697281 0.88 ENST00000524114.1
ENST00000553390.1
ENST00000554914.1
PINX1
SOX7
SOX7
PIN2/TERF1 interacting, telomerase inhibitor 1
SRY (sex determining region Y)-box 7
Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7
chr21_+_17443521 0.87 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr11_-_1593150 0.87 ENST00000397374.3
DUSP8
dual specificity phosphatase 8
chr3_+_8543533 0.84 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr1_+_52082751 0.82 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
OSBPL9
oxysterol binding protein-like 9
chr7_+_128312346 0.82 ENST00000480462.1
ENST00000378704.3
ENST00000477515.1
FAM71F2
family with sequence similarity 71, member F2
chr1_-_221915418 0.82 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr22_+_38597889 0.81 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr8_-_95274536 0.81 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr12_-_110011288 0.80 ENST00000540016.1
ENST00000266839.5
MMAB
methylmalonic aciduria (cobalamin deficiency) cblB type
chr20_-_44420507 0.80 ENST00000243938.4
WFDC3
WAP four-disulfide core domain 3
chr12_+_56521840 0.79 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr19_-_18392422 0.79 ENST00000252818.3
JUND
jun D proto-oncogene
chr6_+_89791507 0.78 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr16_+_3068393 0.78 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr3_+_141105235 0.78 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr11_-_82782861 0.78 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr3_-_99594948 0.77 ENST00000471562.1
ENST00000495625.2
FILIP1L
filamin A interacting protein 1-like
chr19_+_8455077 0.77 ENST00000328024.6
RAB11B
RAB11B, member RAS oncogene family
chr2_+_11864458 0.77 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
LPIN1
lipin 1
chr17_-_4643114 0.77 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr6_-_41888843 0.76 ENST00000434077.1
ENST00000409312.1
MED20
mediator complex subunit 20
chr11_+_111473108 0.75 ENST00000304987.3
SIK2
salt-inducible kinase 2
chr14_+_102276192 0.75 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr17_-_7835228 0.75 ENST00000303731.4
ENST00000571947.1
ENST00000540486.1
ENST00000572656.1
TRAPPC1
trafficking protein particle complex 1
chr12_+_71833756 0.74 ENST00000536515.1
ENST00000540815.2
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr11_-_119234876 0.74 ENST00000525735.1
USP2
ubiquitin specific peptidase 2
chr2_+_28615669 0.72 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr12_+_7282795 0.71 ENST00000266546.6
CLSTN3
calsyntenin 3
chr1_-_86622421 0.69 ENST00000370571.2
COL24A1
collagen, type XXIV, alpha 1
chr13_-_52378231 0.69 ENST00000280056.2
ENST00000444610.2
DHRS12
dehydrogenase/reductase (SDR family) member 12
chr4_+_170581213 0.68 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr8_-_66754172 0.68 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr9_-_131644306 0.67 ENST00000302586.3
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr18_-_33647487 0.67 ENST00000590898.1
ENST00000357384.4
ENST00000319040.6
ENST00000588737.1
ENST00000399022.4
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr4_-_156298028 0.67 ENST00000433024.1
ENST00000379248.2
MAP9
microtubule-associated protein 9
chr1_-_76076793 0.66 ENST00000370859.3
SLC44A5
solute carrier family 44, member 5
chr9_-_131644202 0.66 ENST00000320665.6
ENST00000436267.2
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr20_-_3154162 0.65 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr17_-_43209862 0.65 ENST00000322765.5
PLCD3
phospholipase C, delta 3
chr19_+_50979753 0.64 ENST00000597426.1
ENST00000334976.6
ENST00000376918.3
ENST00000598585.1
EMC10
ER membrane protein complex subunit 10
chr19_-_8809139 0.64 ENST00000324436.3
ACTL9
actin-like 9
chr13_+_111855414 0.63 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr5_-_138210977 0.63 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr17_+_4046462 0.63 ENST00000577075.2
ENST00000575251.1
ENST00000301391.3
CYB5D2
cytochrome b5 domain containing 2
chr4_+_170541678 0.62 ENST00000360642.3
ENST00000512813.1
CLCN3
chloride channel, voltage-sensitive 3
chr2_-_160473114 0.62 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr17_+_25621102 0.61 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WSB1
WD repeat and SOCS box containing 1
chr4_+_170541835 0.61 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr19_+_35849362 0.59 ENST00000327809.4
FFAR3
free fatty acid receptor 3
chr1_+_66999268 0.59 ENST00000371039.1
ENST00000424320.1
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr3_-_156877997 0.59 ENST00000295926.3
CCNL1
cyclin L1
chr13_+_111767650 0.59 ENST00000449979.1
ENST00000370623.3
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr1_+_212738676 0.57 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr9_-_74980113 0.57 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr17_+_4643337 0.57 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr8_-_142377367 0.56 ENST00000377741.3
GPR20
G protein-coupled receptor 20
chr10_-_3827371 0.55 ENST00000469435.1
KLF6
Kruppel-like factor 6
chr6_+_27833034 0.54 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr7_-_137686791 0.54 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2
cAMP responsive element binding protein 3-like 2
chr19_+_35849723 0.54 ENST00000594310.1
FFAR3
free fatty acid receptor 3
chr4_+_145567297 0.54 ENST00000434550.2
HHIP
hedgehog interacting protein
chr3_-_99595037 0.54 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr20_+_35201993 0.54 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr14_+_21498666 0.53 ENST00000481535.1
TPPP2
tubulin polymerization-promoting protein family member 2
chr7_+_44646162 0.53 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr9_-_99381660 0.53 ENST00000375240.3
ENST00000463569.1
CDC14B
cell division cycle 14B
chr9_+_34989638 0.52 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr14_+_74353320 0.51 ENST00000540593.1
ENST00000555730.1
ZNF410
zinc finger protein 410
chr15_-_30113676 0.51 ENST00000400011.2
TJP1
tight junction protein 1
chr17_+_4643300 0.50 ENST00000433935.1
ZMYND15
zinc finger, MYND-type containing 15
chr17_-_80231557 0.50 ENST00000392334.2
ENST00000314028.6
CSNK1D
casein kinase 1, delta
chr10_-_64576105 0.49 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr11_-_118122996 0.49 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr11_+_18343800 0.49 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr6_+_32944119 0.48 ENST00000606059.1
BRD2
bromodomain containing 2
chr9_+_130830451 0.48 ENST00000373068.2
ENST00000373069.5
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr6_-_34664612 0.48 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr6_-_121655593 0.48 ENST00000398212.2
TBC1D32
TBC1 domain family, member 32
chr9_-_73029540 0.48 ENST00000377126.2
KLF9
Kruppel-like factor 9
chrX_+_84499081 0.47 ENST00000276123.3
ZNF711
zinc finger protein 711
chr6_+_44214824 0.47 ENST00000371646.5
ENST00000353801.3
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr9_+_131644398 0.47 ENST00000372599.3
LRRC8A
leucine rich repeat containing 8 family, member A
chr6_+_139456226 0.46 ENST00000367658.2
HECA
headcase homolog (Drosophila)
chr19_-_40919271 0.46 ENST00000291825.7
ENST00000324001.7
PRX
periaxin
chr16_-_27561209 0.46 ENST00000356183.4
ENST00000561623.1
GTF3C1
general transcription factor IIIC, polypeptide 1, alpha 220kDa
chr3_-_15374659 0.45 ENST00000426925.1
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr17_+_56769924 0.45 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr3_-_119182523 0.45 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr1_-_86861660 0.45 ENST00000486215.1
ODF2L
outer dense fiber of sperm tails 2-like
chr11_-_3818688 0.45 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
NUP98
nucleoporin 98kDa
chr2_-_160472952 0.45 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr2_+_10183651 0.45 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr19_+_54371114 0.45 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM
myeloid-associated differentiation marker
chr5_-_54281407 0.45 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr22_-_44258360 0.44 ENST00000330884.4
ENST00000249130.5
SULT4A1
sulfotransferase family 4A, member 1
chr1_-_17380630 0.44 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr7_-_19813192 0.44 ENST00000422233.1
ENST00000433641.1
TMEM196
transmembrane protein 196
chr19_+_35861831 0.44 ENST00000454971.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr9_+_34990219 0.44 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr18_+_20513782 0.44 ENST00000399722.2
ENST00000399725.2
ENST00000399721.2
ENST00000583594.1
RBBP8
retinoblastoma binding protein 8
chr12_-_4554780 0.44 ENST00000228837.2
FGF6
fibroblast growth factor 6
chr6_-_41888814 0.43 ENST00000409060.1
ENST00000265350.4
MED20
mediator complex subunit 20
chr2_+_11052054 0.43 ENST00000295082.1
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr19_+_55996316 0.43 ENST00000205194.4
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr2_-_202645835 0.42 ENST00000264276.6
ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr4_+_170541660 0.42 ENST00000513761.1
ENST00000347613.4
CLCN3
chloride channel, voltage-sensitive 3
chr10_+_119000604 0.42 ENST00000298472.5
SLC18A2
solute carrier family 18 (vesicular monoamine transporter), member 2
chr18_+_20513278 0.42 ENST00000327155.5
RBBP8
retinoblastoma binding protein 8
chr9_+_130860810 0.42 ENST00000433501.1
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr12_-_12715266 0.42 ENST00000228862.2
DUSP16
dual specificity phosphatase 16
chr11_+_4116005 0.41 ENST00000300738.5
RRM1
ribonucleotide reductase M1
chrX_+_84498989 0.41 ENST00000395402.1
ZNF711
zinc finger protein 711
chr2_-_183106641 0.41 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr9_+_131644388 0.41 ENST00000372600.4
LRRC8A
leucine rich repeat containing 8 family, member A
chr5_-_32174369 0.41 ENST00000265070.6
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr11_+_82783097 0.41 ENST00000501011.2
ENST00000527627.1
ENST00000526795.1
ENST00000533528.1
ENST00000533708.1
ENST00000534499.1
RAB30-AS1
RAB30 antisense RNA 1 (head to head)
chr2_-_86850949 0.40 ENST00000237455.4
RNF103
ring finger protein 103
chr9_+_130860583 0.40 ENST00000373064.5
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr6_-_112575838 0.40 ENST00000455073.1
LAMA4
laminin, alpha 4
chr16_-_10674528 0.40 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr11_+_12696102 0.40 ENST00000527636.1
ENST00000527376.1
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chrX_+_84499038 0.39 ENST00000373165.3
ZNF711
zinc finger protein 711
chr8_-_141810634 0.39 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr12_-_122879969 0.39 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr2_-_27531313 0.39 ENST00000296099.2
UCN
urocortin
chr18_+_76829385 0.39 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr4_+_145567173 0.39 ENST00000296575.3
HHIP
hedgehog interacting protein
chr14_+_68086515 0.38 ENST00000261783.3
ARG2
arginase 2
chr19_+_35862192 0.38 ENST00000597214.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr11_+_4116054 0.38 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr8_+_42128812 0.38 ENST00000520810.1
ENST00000416505.2
ENST00000519735.1
ENST00000520835.1
ENST00000379708.3
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr9_+_131644781 0.37 ENST00000259324.5
LRRC8A
leucine rich repeat containing 8 family, member A
chr4_+_108745711 0.37 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr3_+_25469802 0.37 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr1_-_242162375 0.37 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr3_+_156544057 0.37 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
LEKR1
leucine, glutamate and lysine rich 1
chr17_+_27071002 0.36 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TRAF4
TNF receptor-associated factor 4
chr13_+_111767582 0.36 ENST00000375741.2
ENST00000375739.2
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5 1.4 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.4 2.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.4 1.2 GO:1902310 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.4 1.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.4 1.1 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 2.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.3 1.1 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.3 2.8 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.2 0.9 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 0.7 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2 1.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 1.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 2.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 2.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 0.8 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.2 3.5 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.6 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 12.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 0.8 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2 0.5 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.4 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 1.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.6 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.1 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.1 1.6 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.4 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.6 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 3.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.6 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.5 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.7 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.8 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.3 GO:0052314 terpene metabolic process(GO:0042214) phytoalexin metabolic process(GO:0052314)
0.1 1.1 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.9 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.3 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 2.0 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 1.0 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 1.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.4 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 1.1 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.3 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 1.9 GO:0051775 response to redox state(GO:0051775)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.5 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 1.1 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.3 GO:0015866 ADP transport(GO:0015866)
0.1 2.9 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.6 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.1 GO:0060067 cervix development(GO:0060067)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.2 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.5 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 4.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.7 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637)
0.1 0.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.5 GO:0051414 response to cortisol(GO:0051414)
0.1 1.1 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.1 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.3 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.5 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.4 GO:0070836 caveola assembly(GO:0070836)
0.1 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 2.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.9 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.1 1.5 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.2 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1 4.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.3 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.2 GO:0031081 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.1 0.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.7 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 1.0 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.8 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.7 GO:0015871 choline transport(GO:0015871)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.6 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 2.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.4 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.8 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.2 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0097212 lysosomal membrane organization(GO:0097212)
0.0 0.8 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.6 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 0.2 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.1 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0 0.4 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.3 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.9 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.4 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.0 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.5 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0097278 complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.2 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.1 GO:0046985 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.0 GO:0072717 response to actinomycin D(GO:0072716) cellular response to actinomycin D(GO:0072717)
0.0 0.4 GO:0003016 respiratory system process(GO:0003016)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.4 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.3 GO:0050779 RNA destabilization(GO:0050779)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.6 1.9 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.6 4.9 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 0.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 1.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 0.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 1.0 GO:0035976 AP1 complex(GO:0035976)
0.1 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.6 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.4 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 2.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.6 GO:0000322 storage vacuole(GO:0000322)
0.1 0.4 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 1.0 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 1.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.0 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 4.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 13.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 2.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.0 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 1.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 2.2 GO:0050436 microfibril binding(GO:0050436)
0.4 2.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.4 1.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.3 1.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 1.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 3.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 1.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 1.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 0.6 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.2 0.6 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 0.8 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 2.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.5 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.2 3.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 0.5 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.2 2.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.4 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.9 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.5 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 6.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.3 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.3 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 1.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.3 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 1.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.3 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.1 1.1 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.4 GO:0030507 spectrin binding(GO:0030507)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 1.4 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328) modified amino acid transmembrane transporter activity(GO:0072349)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 3.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 5.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol