Inflammatory response time course, HUVEC (Wada et al., 2009)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
ENSG00000146592.12 | cAMP responsive element binding protein 5 | |
ENSG00000095794.15 | cAMP responsive element modulator | |
ENSG00000171223.4 | JunB proto-oncogene, AP-1 transcription factor subunit |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
CREM | hg19_v2_chr10_+_35416090_35416138 | 0.68 | 1.7e-04 | Click! |
JUNB | hg19_v2_chr19_+_12902289_12902310 | 0.28 | 1.7e-01 | Click! |
CREB5 | hg19_v2_chr7_+_28452130_28452154 | -0.21 | 3.1e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 12.2 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
0.1 | 4.6 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
0.1 | 4.2 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.2 | 3.5 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.1 | 3.2 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
0.1 | 2.9 | GO:1902895 | positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895) |
0.3 | 2.8 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
0.4 | 2.3 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
0.2 | 2.2 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
0.1 | 2.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 13.0 | GO:0005667 | transcription factor complex(GO:0005667) |
0.6 | 4.9 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
0.0 | 4.1 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.6 | 3.2 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
0.0 | 2.6 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
0.1 | 2.2 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
0.0 | 2.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.6 | 1.9 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
0.0 | 1.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.1 | 1.4 | GO:0005577 | fibrinogen complex(GO:0005577) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 13.1 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 6.1 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.2 | 3.4 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
0.2 | 3.1 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.4 | 2.3 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.4 | 2.2 | GO:0050436 | microfibril binding(GO:0050436) |
0.2 | 2.2 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.2 | 2.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.2 | 1.9 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.3 | 1.8 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 13.8 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.0 | 2.3 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
0.0 | 2.3 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
0.0 | 2.1 | PID E2F PATHWAY | E2F transcription factor network |
0.0 | 1.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
0.0 | 1.4 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.0 | 1.4 | PID FOXO PATHWAY | FoxO family signaling |
0.0 | 1.4 | PID LKB1 PATHWAY | LKB1 signaling events |
0.0 | 1.2 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
0.1 | 1.1 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 5.6 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.1 | 3.0 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.0 | 2.0 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
0.1 | 1.7 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
0.1 | 1.5 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
0.0 | 1.5 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.1 | 1.4 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.0 | 1.4 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
0.1 | 1.3 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
0.0 | 1.3 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |