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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CREB5_CREM_JUNB

Z-value: 1.02

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Transcription factors associated with CREB5_CREM_JUNB

Gene Symbol Gene ID Gene Info
ENSG00000146592.12 cAMP responsive element binding protein 5
ENSG00000095794.15 cAMP responsive element modulator
ENSG00000171223.4 JunB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREMhg19_v2_chr10_+_35416090_354161380.681.7e-04Click!
JUNBhg19_v2_chr19_+_12902289_129023100.281.7e-01Click!
CREB5hg19_v2_chr7_+_28452130_28452154-0.213.1e-01Click!

Activity profile of CREB5_CREM_JUNB motif

TNFa_0h_00minTNFa_0h_15minTNFa_0h_30minTNFa_0h_45minTNFa_1h_00minTNFa_1h_15minTNFa_1h_30minTNFa_1h_45minTNFa_2h_00minTNFa_2h_15minTNFa_2h_30minTNFa_2h_45minTNFa_3h_00minTNFa_3h_15minTNFa_3h_30minTNFa_3h_45minTNFa_4h_00minTNFa_4h_30minTNFa_5h_00minTNFa_5h_30minTNFa_6h_00minTNFa_6h_30minTNFa_7h_00minTNFa_7h_30minTNFa_8h_00min−0.03−0.02−0.0100.010.020.03
activity (log2(tpm) per TFBS)

Sorted Z-values of CREB5_CREM_JUNB motif

−1.5−1−0.500.511.522.53TNFa_8h_00minTNFa_6h_30minTNFa_6h_00minTNFa_7h_30minTNFa_0h_00minTNFa_7h_00minTNFa_4h_30minTNFa_1h_30minTNFa_5h_30minTNFa_0h_30minTNFa_1h_45minTNFa_3h_30minTNFa_0h_15minTNFa_2h_15minTNFa_1h_15minTNFa_2h_00minTNFa_4h_00minTNFa_3h_45minTNFa_5h_00minTNFa_3h_00minTNFa_2h_45minTNFa_3h_15minTNFa_1h_00minTNFa_0h_45minTNFa_2h_30min
Z-value

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: