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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CUUUGGU

Z-value: 0.58

Motif logo

miRNA associated with seed CUUUGGU

NamemiRBASE accession
MIMAT0000441

Activity profile of CUUUGGU motif

Sorted Z-values of CUUUGGU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_82462425 1.31 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
family with sequence similarity 46, member A
chr5_-_131826457 1.28 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chr16_-_65155833 1.19 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_-_120612240 1.19 ENST00000256646.2
notch 2
chr2_-_208030647 1.09 ENST00000309446.6
Kruppel-like factor 7 (ubiquitous)
chr9_+_116917807 1.07 ENST00000356083.3
collagen, type XXVII, alpha 1
chr6_+_116601265 0.95 ENST00000452085.3
dermatan sulfate epimerase
chr21_-_37838739 0.92 ENST00000399139.1
claudin 14
chr5_+_135364584 0.91 ENST00000442011.2
ENST00000305126.8
transforming growth factor, beta-induced, 68kDa
chr1_+_65613217 0.90 ENST00000545314.1
adenylate kinase 4
chr7_-_41742697 0.89 ENST00000242208.4
inhibin, beta A
chr12_+_27485823 0.89 ENST00000395901.2
ENST00000546179.1
aryl hydrocarbon receptor nuclear translocator-like 2
chr3_-_123603137 0.87 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
myosin light chain kinase
chr9_+_115913222 0.85 ENST00000259392.3
solute carrier family 31 (copper transporter), member 2
chr2_+_112812778 0.84 ENST00000283206.4
transmembrane protein 87B
chr7_-_25019760 0.81 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
oxysterol binding protein-like 3
chr13_-_26625169 0.78 ENST00000319420.3
shisa family member 2
chr3_+_29322803 0.78 ENST00000396583.3
ENST00000383767.2
RNA binding motif, single stranded interacting protein 3
chr3_+_154797428 0.76 ENST00000460393.1
membrane metallo-endopeptidase
chr2_+_75061108 0.76 ENST00000290573.2
hexokinase 2
chr5_-_131563501 0.76 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
prolyl 4-hydroxylase, alpha polypeptide II
chr2_-_197457335 0.71 ENST00000260983.3
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr4_-_157892498 0.71 ENST00000502773.1
platelet derived growth factor C
chr20_-_3996036 0.70 ENST00000336095.6
ring finger protein 24
chr3_+_105085734 0.69 ENST00000306107.5
activated leukocyte cell adhesion molecule
chr3_-_164913777 0.68 ENST00000475390.1
SLIT and NTRK-like family, member 3
chr15_-_42264702 0.68 ENST00000220325.4
EH-domain containing 4
chr1_+_155108294 0.67 ENST00000303343.8
ENST00000368404.4
ENST00000368401.5
solute carrier family 50 (sugar efflux transporter), member 1
chr7_+_28452130 0.66 ENST00000357727.2
cAMP responsive element binding protein 5
chr12_+_66217911 0.63 ENST00000403681.2
high mobility group AT-hook 2
chr8_+_22224811 0.62 ENST00000381237.1
solute carrier family 39 (zinc transporter), member 14
chr9_-_38069208 0.60 ENST00000377707.3
ENST00000377700.4
Src homology 2 domain containing adaptor protein B
chr14_+_52118576 0.60 ENST00000395718.2
ENST00000344768.5
FERM domain containing 6
chr3_-_107809816 0.59 ENST00000361309.5
ENST00000355354.7
CD47 molecule
chr12_-_111021110 0.59 ENST00000354300.3
PTC7 protein phosphatase homolog (S. cerevisiae)
chr3_-_98620500 0.59 ENST00000326840.6
discoidin, CUB and LCCL domain containing 2
chr17_+_46985731 0.57 ENST00000360943.5
ubiquitin-conjugating enzyme E2Z
chr5_+_173315283 0.54 ENST00000265085.5
cytoplasmic polyadenylation element binding protein 4
chr1_+_107683644 0.54 ENST00000370067.1
netrin G1
chr12_-_89918522 0.53 ENST00000529983.2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr6_-_128841503 0.53 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
protein tyrosine phosphatase, receptor type, K
chr2_+_74425689 0.51 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr17_-_62658186 0.51 ENST00000262435.9
SMAD specific E3 ubiquitin protein ligase 2
chr6_+_114178512 0.50 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr3_-_64673289 0.50 ENST00000295903.4
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr17_-_49198216 0.50 ENST00000262013.7
ENST00000357122.4
sperm associated antigen 9
chr10_+_101419187 0.49 ENST00000370489.4
ectonucleoside triphosphate diphosphohydrolase 7
chr1_+_25071848 0.49 ENST00000374379.4
chloride intracellular channel 4
chr1_-_169455169 0.49 ENST00000367804.4
ENST00000236137.5
solute carrier family 19 (thiamine transporter), member 2
chr8_-_144897549 0.48 ENST00000356994.2
ENST00000320476.3
scribbled planar cell polarity protein
chr13_-_33859819 0.48 ENST00000336934.5
StAR-related lipid transfer (START) domain containing 13
chr8_-_119124045 0.48 ENST00000378204.2
exostosin glycosyltransferase 1
chr22_-_42017021 0.48 ENST00000263256.6
desumoylating isopeptidase 1
chr17_+_21187976 0.47 ENST00000342679.4
mitogen-activated protein kinase kinase 3
chr13_-_30169807 0.47 ENST00000380752.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr12_-_89919965 0.46 ENST00000548729.1
POC1B-GALNT4 readthrough
chr6_+_138483058 0.45 ENST00000251691.4
KIAA1244
chr11_+_122526383 0.45 ENST00000284273.5
ubiquitin associated and SH3 domain containing B
chr15_+_59063478 0.45 ENST00000559228.1
ENST00000450403.2
family with sequence similarity 63, member B
chr22_+_38302285 0.44 ENST00000215957.6
MICAL-like 1
chr6_+_106546808 0.43 ENST00000369089.3
PR domain containing 1, with ZNF domain
chr14_-_24658053 0.42 ENST00000354464.6
importin 4
chr1_-_27816556 0.41 ENST00000536657.1
WAS protein family, member 2
chr18_+_55102917 0.41 ENST00000491143.2
one cut homeobox 2
chr12_+_69004619 0.41 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B, member of RAS oncogene family
chr2_+_85981008 0.40 ENST00000306279.3
atonal homolog 8 (Drosophila)
chr14_-_53258314 0.40 ENST00000216410.3
ENST00000557604.1
glucosamine-phosphate N-acetyltransferase 1
chr11_+_35965531 0.40 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
low density lipoprotein receptor class A domain containing 3
chr6_-_169654139 0.39 ENST00000366787.3
thrombospondin 2
chr12_+_113229737 0.39 ENST00000551052.1
ENST00000415485.3
rabphilin 3A homolog (mouse)
chr10_-_105615164 0.39 ENST00000355946.2
ENST00000369774.4
SH3 and PX domains 2A
chr1_-_27481401 0.39 ENST00000263980.3
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chr1_+_93811438 0.37 ENST00000370272.4
ENST00000370267.1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr22_-_45636650 0.37 ENST00000336156.5
KIAA0930
chr2_-_119605253 0.36 ENST00000295206.6
engrailed homeobox 1
chr5_+_56111361 0.36 ENST00000399503.3
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr3_-_142166904 0.36 ENST00000264951.4
5'-3' exoribonuclease 1
chr1_+_206858232 0.36 ENST00000294981.4
mitogen-activated protein kinase-activated protein kinase 2
chr4_-_159593179 0.36 ENST00000379205.4
chromosome 4 open reading frame 46
chr2_+_210636697 0.35 ENST00000439458.1
ENST00000272845.6
unc-80 homolog (C. elegans)
chr14_-_77279153 0.35 ENST00000251089.2
angel homolog 1 (Drosophila)
chr1_-_19283163 0.35 ENST00000455833.2
intermediate filament family orphan 2
chr1_+_50574585 0.35 ENST00000371824.1
ENST00000371823.4
ELAV like neuron-specific RNA binding protein 4
chr2_-_69614373 0.34 ENST00000361060.5
ENST00000357308.4
glutamine--fructose-6-phosphate transaminase 1
chr1_-_197169672 0.34 ENST00000367405.4
zinc finger and BTB domain containing 41
chr1_+_37940153 0.34 ENST00000373087.6
zinc finger CCCH-type containing 12A
chr5_+_102594403 0.33 ENST00000319933.2
chromosome 5 open reading frame 30
chr11_-_46142948 0.33 ENST00000257821.4
PHD finger protein 21A
chr3_+_30648066 0.33 ENST00000359013.4
transforming growth factor, beta receptor II (70/80kDa)
chr5_+_34656331 0.33 ENST00000265109.3
retinoic acid induced 14
chr6_+_126112001 0.33 ENST00000392477.2
nuclear receptor coactivator 7
chr20_+_35974532 0.33 ENST00000373578.2
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr15_+_73344791 0.33 ENST00000261908.6
neogenin 1
chr17_-_78450398 0.33 ENST00000306773.4
neuronal pentraxin I
chr11_-_79151695 0.33 ENST00000278550.7
teneurin transmembrane protein 4
chr2_+_26568965 0.32 ENST00000260585.7
ENST00000447170.1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr10_+_24755416 0.32 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr7_+_156931606 0.32 ENST00000348165.5
ubiquitin protein ligase E3C
chr15_-_75744014 0.32 ENST00000394947.3
ENST00000565264.1
SIN3 transcription regulator family member A
chr12_-_56224546 0.32 ENST00000357606.3
ENST00000547445.1
DnaJ (Hsp40) homolog, subfamily C, member 14
chr10_+_13142075 0.31 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
optineurin
chr12_-_113909877 0.31 ENST00000261731.3
LIM homeobox 5
chr12_-_10875831 0.31 ENST00000279550.7
ENST00000228251.4
Y box binding protein 3
chr15_-_48937982 0.30 ENST00000316623.5
fibrillin 1
chr11_-_128392085 0.30 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr22_+_39101728 0.30 ENST00000216044.5
ENST00000484657.1
GTP binding protein 1
chr13_+_26828275 0.30 ENST00000381527.3
cyclin-dependent kinase 8
chr17_-_1395954 0.29 ENST00000359786.5
myosin IC
chr2_-_235405679 0.29 ENST00000390645.2
ADP-ribosylation factor-like 4C
chr20_-_41818373 0.29 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
protein tyrosine phosphatase, receptor type, T
chr3_+_36421826 0.29 ENST00000273183.3
SH3 and cysteine rich domain
chr16_+_30669720 0.29 ENST00000356166.6
fibrosin
chr3_-_119813264 0.29 ENST00000264235.8
glycogen synthase kinase 3 beta
chr11_-_9113137 0.28 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
signal peptide, CUB domain, EGF-like 2
chr1_-_22469459 0.28 ENST00000290167.6
wingless-type MMTV integration site family, member 4
chr7_-_98741642 0.28 ENST00000361368.2
SMAD specific E3 ubiquitin protein ligase 1
chr15_+_42787452 0.28 ENST00000249647.3
synaptosomal-associated protein, 23kDa
chr21_-_15755446 0.28 ENST00000544452.1
ENST00000285667.3
heat shock protein 70kDa family, member 13
chr9_+_137218362 0.28 ENST00000481739.1
retinoid X receptor, alpha
chr2_-_161350305 0.28 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr6_-_46293378 0.28 ENST00000330430.6
regulator of calcineurin 2
chrX_+_95939711 0.28 ENST00000373049.4
ENST00000324765.8
diaphanous-related formin 2
chr3_+_32859510 0.27 ENST00000383763.5
tripartite motif containing 71, E3 ubiquitin protein ligase
chr16_+_19125252 0.27 ENST00000566735.1
ENST00000381440.3
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr16_+_57220193 0.27 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
ring finger and SPRY domain containing 1
chr8_-_134309335 0.27 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
N-myc downstream regulated 1
chr2_+_114647504 0.26 ENST00000263238.2
ARP3 actin-related protein 3 homolog (yeast)
chr20_+_46130601 0.26 ENST00000341724.6
nuclear receptor coactivator 3
chr4_-_170924888 0.26 ENST00000502832.1
ENST00000393704.3
microfibrillar-associated protein 3-like
chr1_+_26737253 0.26 ENST00000326279.6
lin-28 homolog A (C. elegans)
chr9_-_115095883 0.26 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
polypyrimidine tract binding protein 3
chr11_+_118477144 0.26 ENST00000361417.2
pleckstrin homology-like domain, family B, member 1
chr5_-_16936340 0.26 ENST00000507288.1
ENST00000513610.1
myosin X
chr19_+_1941117 0.25 ENST00000255641.8
casein kinase 1, gamma 2
chr2_+_73144604 0.25 ENST00000258106.6
empty spiracles homeobox 1
chr4_+_81187753 0.25 ENST00000312465.7
ENST00000456523.3
fibroblast growth factor 5
chr17_+_64298944 0.25 ENST00000413366.3
protein kinase C, alpha
chr5_-_76788317 0.25 ENST00000296679.4
WD repeat domain 41
chr19_+_16771936 0.25 ENST00000187762.2
ENST00000599479.1
transmembrane protein 38A
chr2_+_228336849 0.25 ENST00000409979.2
ENST00000310078.8
ArfGAP with FG repeats 1
chr1_+_179262905 0.24 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
sterol O-acyltransferase 1
chr17_-_48072574 0.24 ENST00000434704.2
distal-less homeobox 3
chr4_+_103422471 0.24 ENST00000226574.4
ENST00000394820.4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_+_27561007 0.24 ENST00000319394.3
WD and tetratricopeptide repeats 1
chr1_+_15943995 0.24 ENST00000480945.1
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chrX_-_25034065 0.24 ENST00000379044.4
aristaless related homeobox
chr1_-_38273840 0.24 ENST00000373044.2
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr19_-_17799008 0.24 ENST00000519716.2
unc-13 homolog A (C. elegans)
chr14_+_70078303 0.24 ENST00000342745.4
KIAA0247
chr2_-_158485387 0.24 ENST00000243349.8
activin A receptor, type IC
chr1_-_161102421 0.24 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
death effector domain containing
chr17_+_36886478 0.24 ENST00000439660.2
CDGSH iron sulfur domain 3
chr15_-_78369994 0.23 ENST00000300584.3
ENST00000409931.3
TBC1 domain family, member 2B
chr1_+_205473720 0.23 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr7_-_23510086 0.23 ENST00000258729.3
insulin-like growth factor 2 mRNA binding protein 3
chr16_-_79634595 0.23 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr21_-_36260980 0.23 ENST00000344691.4
ENST00000358356.5
runt-related transcription factor 1
chr15_+_59730348 0.23 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
family with sequence similarity 81, member A
chr8_+_22462145 0.23 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
cell cycle and apoptosis regulator 2
chr3_-_138553594 0.22 ENST00000477593.1
ENST00000483968.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr5_+_175875349 0.22 ENST00000261942.6
Fas associated factor family member 2
chr12_+_56511943 0.22 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr15_+_69591235 0.22 ENST00000395407.2
ENST00000558684.1
progestin and adipoQ receptor family member V
chr10_-_61666267 0.22 ENST00000263102.6
coiled-coil domain containing 6
chr9_-_35732362 0.22 ENST00000314888.9
ENST00000540444.1
talin 1
chr15_+_81293254 0.21 ENST00000267984.2
mesoderm development candidate 1
chr10_-_27149792 0.21 ENST00000376140.3
ENST00000376170.4
abl-interactor 1
chr14_-_47812321 0.21 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MAM domain containing glycosylphosphatidylinositol anchor 2
chr7_+_155250824 0.21 ENST00000297375.4
engrailed homeobox 2
chr4_-_82136114 0.21 ENST00000395578.1
ENST00000418486.2
protein kinase, cGMP-dependent, type II
chr17_-_6459768 0.21 ENST00000421306.3
PITPNM family member 3
chr22_-_36784035 0.21 ENST00000216181.5
myosin, heavy chain 9, non-muscle
chr20_+_23342783 0.21 ENST00000544236.1
ENST00000338121.5
ENST00000542987.1
ENST00000424216.1
GDNF-inducible zinc finger protein 1
chr22_-_18507279 0.21 ENST00000441493.2
ENST00000444520.1
ENST00000207726.7
ENST00000429452.1
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr3_+_197476621 0.21 ENST00000241502.4
forty-two-three domain containing 1
chr17_+_4901199 0.21 ENST00000320785.5
ENST00000574165.1
kinesin family member 1C
chr6_-_167040731 0.20 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr7_-_100183742 0.20 ENST00000310300.6
leucine-rich repeats and calponin homology (CH) domain containing 4
chr2_+_46769798 0.20 ENST00000238738.4
ras homolog family member Q
chr12_+_45609893 0.20 ENST00000320560.8
anoctamin 6
chr13_+_96329381 0.20 ENST00000602402.1
ENST00000376795.6
DnaJ (Hsp40) homolog, subfamily C, member 3
chr1_-_116383738 0.20 ENST00000320238.3
nescient helix loop helix 2
chr4_+_48343339 0.20 ENST00000264313.6
SLAIN motif family, member 2
chr10_+_121652204 0.20 ENST00000369075.3
ENST00000543134.1
SEC23 interacting protein
chr11_+_64126614 0.20 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr4_+_113970772 0.19 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr15_-_56209306 0.19 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr12_-_498620 0.19 ENST00000399788.2
ENST00000382815.4
lysine (K)-specific demethylase 5A
chr7_+_39989611 0.19 ENST00000181839.4
cyclin-dependent kinase 13
chr11_-_96076334 0.19 ENST00000524717.1
mastermind-like 2 (Drosophila)
chr5_+_162864575 0.19 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr14_-_55369525 0.19 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GTP cyclohydrolase 1
chr9_-_135996537 0.19 ENST00000372050.3
ENST00000372047.3
ral guanine nucleotide dissociation stimulator
chr12_+_27932803 0.19 ENST00000381271.2
kelch-like family member 42
chr17_+_28804380 0.18 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
golgi SNAP receptor complex member 1
chr4_+_86396265 0.18 ENST00000395184.1
Rho GTPase activating protein 24
chr2_+_36582857 0.18 ENST00000280527.2
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr2_+_191045562 0.18 ENST00000340623.4
chromosome 2 open reading frame 88
chr11_+_57435219 0.18 ENST00000527985.1
ENST00000287169.3
zinc finger, DHHC-type containing 5
chr10_-_121632266 0.18 ENST00000360003.3
ENST00000369077.3
minichromosome maintenance complex binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of CUUUGGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 1.3 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 0.7 GO:1901656 glycoside transport(GO:1901656)
0.2 1.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 0.5 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.2 0.6 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.2 0.8 GO:0071492 creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492)
0.1 0.6 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.4 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.4 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.1 0.5 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.5 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.8 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.3 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 0.3 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.2 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0061054 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) renal vesicle induction(GO:0072034)
0.1 0.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.3 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 1.2 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.9 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.4 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.6 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.5 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.4 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.1 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.6 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.1 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.5 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.2 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.3 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.2 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.8 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.3 GO:1904996 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.3 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.5 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:1903923 establishment of meiotic spindle localization(GO:0051295) protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.0 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920) parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.3 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.6 GO:0008228 opsonization(GO:0008228)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.2 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 1.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.8 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.3 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:2000546 intramembranous ossification(GO:0001957) direct ossification(GO:0036072) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:1905073 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.5 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.3 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.0 0.5 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.0 GO:0003180 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.7 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:1903540 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.5 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.5 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 1.2 GO:0032433 filopodium tip(GO:0032433)
0.1 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.1 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 2.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.2 0.9 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 0.9 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 0.5 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.2 0.5 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 0.6 GO:0035501 MH1 domain binding(GO:0035501)
0.1 0.5 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.8 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.6 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.8 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 1.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.9 REACTOME AMYLOIDS Genes involved in Amyloids