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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CUX1

Z-value: 1.14

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Transcription factors associated with CUX1

Gene Symbol Gene ID Gene Info
CUX1
ENSG00000257923.5 cut like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CUX1hg19_v2_chr7_+_101459263_101459310-0.442.9e-02Click!

Activity profile of CUX1 motif

Sorted Z-values of CUX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_4229495 2.76 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr11_-_72385437 2.49 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr1_-_209824643 2.14 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr6_+_31554826 2.14 ENST00000376089.2
ENST00000396112.2
LST1
leukocyte specific transcript 1
chr11_-_4414880 2.05 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr6_-_32820529 1.94 ENST00000425148.2
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr19_-_55658687 1.83 ENST00000593046.1
TNNT1
troponin T type 1 (skeletal, slow)
chr6_+_32812568 1.79 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr19_-_55658281 1.75 ENST00000585321.2
ENST00000587465.2
TNNT1
troponin T type 1 (skeletal, slow)
chr17_+_77021702 1.71 ENST00000392445.2
ENST00000354124.3
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr6_+_127898312 1.63 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr16_-_65155979 1.45 ENST00000562325.1
ENST00000268603.4
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr17_+_77019030 1.44 ENST00000580454.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr2_+_103035102 1.42 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr17_+_77018896 1.40 ENST00000578229.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr6_+_31554962 1.39 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1
leukocyte specific transcript 1
chr15_-_42448788 1.33 ENST00000382396.4
ENST00000397272.3
PLA2G4F
phospholipase A2, group IVF
chr4_-_177713788 1.31 ENST00000280193.2
VEGFC
vascular endothelial growth factor C
chr1_+_151129103 1.29 ENST00000368910.3
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr14_-_107283278 1.28 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr3_-_123512688 1.24 ENST00000475616.1
MYLK
myosin light chain kinase
chr8_+_104384616 1.22 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr6_+_32811885 1.17 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr1_+_155107820 1.14 ENST00000484157.1
SLC50A1
solute carrier family 50 (sugar efflux transporter), member 1
chr10_-_24770632 1.13 ENST00000596413.1
AL353583.1
AL353583.1
chr6_-_32812420 1.12 ENST00000374881.2
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr1_-_173174681 1.08 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr19_-_43690674 1.05 ENST00000342951.6
ENST00000366175.3
PSG5
pregnancy specific beta-1-glycoprotein 5
chr19_+_8117636 1.01 ENST00000253451.4
ENST00000315626.4
CCL25
chemokine (C-C motif) ligand 25
chr2_+_27719697 0.98 ENST00000264717.2
ENST00000424318.2
GCKR
glucokinase (hexokinase 4) regulator
chr12_+_7072354 0.98 ENST00000537269.1
U47924.27
U47924.27
chr9_-_136344237 0.96 ENST00000432868.1
ENST00000371899.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr11_+_117070037 0.95 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr19_+_10197463 0.95 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr3_-_112218205 0.94 ENST00000383680.4
BTLA
B and T lymphocyte associated
chr2_-_169769787 0.94 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chr1_+_205225319 0.91 ENST00000329800.7
TMCC2
transmembrane and coiled-coil domain family 2
chr17_-_20370847 0.91 ENST00000423676.3
ENST00000324290.5
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr12_-_57522813 0.89 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr6_-_87804815 0.89 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr13_-_80915059 0.87 ENST00000377104.3
SPRY2
sprouty homolog 2 (Drosophila)
chr1_+_156119798 0.86 ENST00000355014.2
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr12_-_71182695 0.85 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr7_+_26191809 0.84 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr6_+_32811861 0.82 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr9_-_136344197 0.80 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr20_-_22559211 0.80 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr13_-_33760216 0.80 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr11_+_35198118 0.79 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44
CD44 molecule (Indian blood group)
chr3_-_112218378 0.78 ENST00000334529.5
BTLA
B and T lymphocyte associated
chr19_-_48059113 0.78 ENST00000391901.3
ENST00000314121.4
ENST00000448976.1
ZNF541
zinc finger protein 541
chr22_+_21133469 0.77 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr1_+_155006300 0.74 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chr17_+_7341586 0.74 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr11_-_117698765 0.70 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chr5_-_135693073 0.70 ENST00000352189.3
ENST00000378459.2
ENST00000502753.2
TRPC7
transient receptor potential cation channel, subfamily C, member 7
chr3_+_173116225 0.68 ENST00000457714.1
NLGN1
neuroligin 1
chr3_-_39234074 0.67 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1
xin actin-binding repeat containing 1
chr7_-_112579869 0.66 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr9_-_97090926 0.66 ENST00000335456.7
ENST00000253262.4
ENST00000341207.4
NUTM2F
NUT family member 2F
chr1_+_159409512 0.66 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr16_+_56659687 0.65 ENST00000568293.1
ENST00000330439.6
MT1E
metallothionein 1E
chr1_-_11120057 0.65 ENST00000376957.2
SRM
spermidine synthase
chr6_-_32811771 0.65 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr7_-_99527243 0.65 ENST00000312891.2
GJC3
gap junction protein, gamma 3, 30.2kDa
chr5_+_98104978 0.65 ENST00000308234.7
RGMB
repulsive guidance molecule family member b
chr22_+_21128167 0.63 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr14_-_70546897 0.63 ENST00000394330.2
ENST00000533541.1
ENST00000216568.7
SLC8A3
solute carrier family 8 (sodium/calcium exchanger), member 3
chr11_-_9286921 0.62 ENST00000328194.3
DENND5A
DENN/MADD domain containing 5A
chr17_+_7942335 0.62 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
ALOX15B
arachidonate 15-lipoxygenase, type B
chr18_-_47376197 0.60 ENST00000592688.1
MYO5B
myosin VB
chr19_-_43690642 0.60 ENST00000407356.1
ENST00000407568.1
ENST00000404580.1
ENST00000599812.1
PSG5
pregnancy specific beta-1-glycoprotein 5
chr1_-_151299842 0.59 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr10_-_120355149 0.59 ENST00000239032.2
PRLHR
prolactin releasing hormone receptor
chr4_+_24797085 0.59 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr12_+_10331605 0.59 ENST00000298530.3
TMEM52B
transmembrane protein 52B
chr1_+_155583012 0.58 ENST00000462250.2
MSTO1
misato 1, mitochondrial distribution and morphology regulator
chr1_+_111773349 0.58 ENST00000533831.2
CHI3L2
chitinase 3-like 2
chr6_+_31554456 0.58 ENST00000339530.4
LST1
leukocyte specific transcript 1
chr9_-_130487143 0.57 ENST00000419060.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr1_-_156786634 0.57 ENST00000392306.2
ENST00000368199.3
SH2D2A
SH2 domain containing 2A
chr12_-_52715179 0.57 ENST00000293670.3
KRT83
keratin 83
chr10_+_90750493 0.56 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr5_+_149980622 0.56 ENST00000394243.1
SYNPO
synaptopodin
chr22_+_21996549 0.56 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr17_-_77925806 0.55 ENST00000574241.2
TBC1D16
TBC1 domain family, member 16
chr6_-_169654139 0.54 ENST00000366787.3
THBS2
thrombospondin 2
chr5_-_16936340 0.54 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr9_-_115983641 0.54 ENST00000238256.3
FKBP15
FK506 binding protein 15, 133kDa
chr6_+_31554612 0.54 ENST00000211921.7
LST1
leukocyte specific transcript 1
chr3_-_147124547 0.54 ENST00000491672.1
ENST00000383075.3
ZIC4
Zic family member 4
chr12_-_111358372 0.54 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr4_-_48018580 0.54 ENST00000514170.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr1_-_67142710 0.53 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr2_-_85636928 0.53 ENST00000449030.1
CAPG
capping protein (actin filament), gelsolin-like
chr16_+_30751953 0.53 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr6_+_31554636 0.53 ENST00000433492.1
LST1
leukocyte specific transcript 1
chr8_+_125985531 0.52 ENST00000319286.5
ZNF572
zinc finger protein 572
chr19_+_35645817 0.52 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr15_-_83953466 0.51 ENST00000345382.2
BNC1
basonuclin 1
chr11_-_3663502 0.51 ENST00000359918.4
ART5
ADP-ribosyltransferase 5
chr16_+_56691838 0.51 ENST00000394501.2
MT1F
metallothionein 1F
chr16_-_84538218 0.51 ENST00000562447.1
ENST00000565765.1
ENST00000535580.1
ENST00000343629.6
TLDC1
TBC/LysM-associated domain containing 1
chr13_-_114107839 0.50 ENST00000375418.3
ADPRHL1
ADP-ribosylhydrolase like 1
chr19_-_42133420 0.49 ENST00000221954.2
ENST00000600925.1
CEACAM4
carcinoembryonic antigen-related cell adhesion molecule 4
chr11_-_123065989 0.49 ENST00000448775.2
CLMP
CXADR-like membrane protein
chr7_-_138458781 0.49 ENST00000393054.1
ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr17_+_7942424 0.49 ENST00000573359.1
ALOX15B
arachidonate 15-lipoxygenase, type B
chr1_-_36948879 0.49 ENST00000373106.1
ENST00000373104.1
ENST00000373103.1
CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr18_+_61575200 0.48 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr22_-_17680472 0.48 ENST00000330232.4
CECR1
cat eye syndrome chromosome region, candidate 1
chr6_+_7541808 0.48 ENST00000379802.3
DSP
desmoplakin
chr5_-_66492562 0.48 ENST00000256447.4
CD180
CD180 molecule
chr20_+_29956369 0.48 ENST00000253381.2
DEFB118
defensin, beta 118
chr9_-_136203235 0.48 ENST00000372022.4
SURF6
surfeit 6
chr6_-_53013620 0.48 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr21_-_15755446 0.47 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr11_+_66742742 0.47 ENST00000308963.4
C11orf86
chromosome 11 open reading frame 86
chr12_+_20848282 0.47 ENST00000545604.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr16_+_30935896 0.46 ENST00000562319.1
ENST00000380310.2
FBXL19
F-box and leucine-rich repeat protein 19
chr12_+_20848377 0.46 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr3_+_169490834 0.46 ENST00000392733.1
MYNN
myoneurin
chr3_+_69985792 0.46 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr1_+_48688357 0.46 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
SLC5A9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr12_+_45609893 0.46 ENST00000320560.8
ANO6
anoctamin 6
chr11_-_62752455 0.45 ENST00000360421.4
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr19_+_10362882 0.45 ENST00000393733.2
ENST00000588502.1
MRPL4
mitochondrial ribosomal protein L4
chr11_-_3663480 0.45 ENST00000397068.3
ART5
ADP-ribosyltransferase 5
chr12_+_49717081 0.44 ENST00000547807.1
ENST00000551567.1
TROAP
trophinin associated protein
chr11_-_85338311 0.44 ENST00000376104.2
DLG2
discs, large homolog 2 (Drosophila)
chr1_-_169703203 0.44 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr1_-_212588157 0.44 ENST00000261455.4
ENST00000535273.1
TMEM206
transmembrane protein 206
chr11_-_62752429 0.44 ENST00000377871.3
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr19_+_51728316 0.43 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33
CD33 molecule
chr16_-_2004683 0.43 ENST00000268661.7
RPL3L
ribosomal protein L3-like
chr20_-_62203808 0.43 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr4_-_103749205 0.43 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr18_-_10787140 0.43 ENST00000383408.2
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr8_+_32406179 0.42 ENST00000405005.3
NRG1
neuregulin 1
chr8_-_91095099 0.42 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr15_-_88799384 0.42 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr4_+_81118647 0.41 ENST00000415738.2
PRDM8
PR domain containing 8
chr3_+_141496990 0.41 ENST00000264952.2
GRK7
G protein-coupled receptor kinase 7
chrX_+_153409678 0.40 ENST00000369951.4
OPN1LW
opsin 1 (cone pigments), long-wave-sensitive
chr17_-_48207157 0.40 ENST00000330175.4
ENST00000503131.1
SAMD14
sterile alpha motif domain containing 14
chr3_+_111717600 0.40 ENST00000273368.4
TAGLN3
transgelin 3
chr10_+_24755416 0.40 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr9_+_139743176 0.39 ENST00000371661.1
ENST00000545326.1
PHPT1
phosphohistidine phosphatase 1
chr13_-_46716969 0.39 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr15_-_48937982 0.39 ENST00000316623.5
FBN1
fibrillin 1
chr1_+_36621529 0.39 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr16_-_48281305 0.39 ENST00000356608.2
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr20_-_45061695 0.39 ENST00000445496.2
ELMO2
engulfment and cell motility 2
chr11_-_65430251 0.39 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr1_+_156123318 0.39 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_-_56685966 0.39 ENST00000334667.2
TMEM68
transmembrane protein 68
chrX_-_153059811 0.38 ENST00000427365.2
ENST00000444450.1
ENST00000370093.1
IDH3G
isocitrate dehydrogenase 3 (NAD+) gamma
chr1_+_168148169 0.38 ENST00000367833.2
TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr22_-_37640277 0.38 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr5_-_176057518 0.38 ENST00000393693.2
SNCB
synuclein, beta
chr1_+_104615595 0.38 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chr3_-_57326704 0.38 ENST00000487349.1
ENST00000389601.3
ASB14
ankyrin repeat and SOCS box containing 14
chr2_-_233352531 0.37 ENST00000304546.1
ECEL1
endothelin converting enzyme-like 1
chr9_+_99691286 0.37 ENST00000372322.3
NUTM2G
NUT family member 2G
chr19_+_52076425 0.37 ENST00000436511.2
ZNF175
zinc finger protein 175
chr2_-_31030277 0.37 ENST00000534090.2
ENST00000295055.8
CAPN13
calpain 13
chr11_-_117698787 0.37 ENST00000260287.2
FXYD2
FXYD domain containing ion transport regulator 2
chrX_-_110513703 0.37 ENST00000324068.1
CAPN6
calpain 6
chr7_+_142364193 0.37 ENST00000390397.2
TRBV24-1
T cell receptor beta variable 24-1
chr16_+_23765948 0.37 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr1_+_156123359 0.37 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_-_56685859 0.36 ENST00000523423.1
ENST00000523073.1
ENST00000519784.1
ENST00000434581.2
ENST00000519780.1
ENST00000521229.1
ENST00000522576.1
ENST00000523180.1
ENST00000522090.1
TMEM68
transmembrane protein 68
chr12_-_58165870 0.36 ENST00000257848.7
METTL1
methyltransferase like 1
chr1_-_72566613 0.36 ENST00000306821.3
NEGR1
neuronal growth regulator 1
chr17_+_7452336 0.36 ENST00000293826.4
TNFSF12-TNFSF13
TNFSF12-TNFSF13 readthrough
chr12_+_49717019 0.35 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP
trophinin associated protein
chr12_-_91574142 0.35 ENST00000547937.1
DCN
decorin
chrX_+_46937745 0.35 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN
regucalcin
chr17_-_18218270 0.35 ENST00000321105.5
TOP3A
topoisomerase (DNA) III alpha
chr15_-_88799661 0.35 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr6_+_29407083 0.35 ENST00000444197.2
OR10C1
olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
chr16_+_67193834 0.34 ENST00000258200.3
ENST00000518148.1
ENST00000519917.1
ENST00000517382.1
ENST00000521920.1
FBXL8
F-box and leucine-rich repeat protein 8
chr2_+_185463093 0.34 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr11_+_36317830 0.34 ENST00000530639.1
PRR5L
proline rich 5 like
chr1_-_159894319 0.34 ENST00000320307.4
TAGLN2
transgelin 2
chr19_+_8117881 0.34 ENST00000390669.3
CCL25
chemokine (C-C motif) ligand 25
chr7_-_142207004 0.34 ENST00000426318.2
TRBV10-2
T cell receptor beta variable 10-2
chr19_-_49945617 0.34 ENST00000600601.1
ENST00000543531.1
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr16_-_67194201 0.34 ENST00000345057.4
TRADD
TNFRSF1A-associated via death domain
chr6_-_22297730 0.34 ENST00000306482.1
PRL
prolactin
chr11_+_113779704 0.34 ENST00000537778.1
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr15_-_35280426 0.33 ENST00000559564.1
ENST00000356321.4
ZNF770
zinc finger protein 770
chr19_+_35849362 0.33 ENST00000327809.4
FFAR3
free fatty acid receptor 3
chr1_-_45288932 0.33 ENST00000438067.1
PTCH2
patched 2
chr19_-_51530916 0.33 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr16_-_58768177 0.33 ENST00000434819.2
ENST00000245206.5
GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial
chr22_-_37213045 0.33 ENST00000406910.2
ENST00000417718.2
PVALB
parvalbumin
chr11_-_40315640 0.33 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr19_-_41220957 0.33 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
ADCK4
aarF domain containing kinase 4
chr1_-_153513170 0.33 ENST00000368717.2
S100A5
S100 calcium binding protein A5

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.6 4.6 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.5 2.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.5 1.9 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 3.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 1.1 GO:1901656 glycoside transport(GO:1901656)
0.4 1.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 0.9 GO:0097254 renal tubular secretion(GO:0097254)
0.3 1.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.3 0.8 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.3 1.3 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.3 0.8 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.2 0.7 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.2 1.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 2.8 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 0.9 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.2 1.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 1.0 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 1.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.6 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1 0.3 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 1.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.6 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.5 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.4 GO:1904833 L-ascorbic acid biosynthetic process(GO:0019853) positive regulation of superoxide dismutase activity(GO:1901671) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of removal of superoxide radicals(GO:1904833)
0.1 0.3 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 0.5 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.3 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.6 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.8 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 1.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.3 GO:0006532 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.3 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 0.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.1 0.7 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.3 GO:0014820 tonic smooth muscle contraction(GO:0014820)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 1.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.3 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.1 0.5 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 2.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.2 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.1 0.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.6 GO:0032439 endosome localization(GO:0032439)
0.1 2.6 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.6 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.1 0.3 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 1.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 1.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.3 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.2 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.8 GO:0015816 glycine transport(GO:0015816)
0.1 0.7 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 0.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 0.5 GO:0071896 protein localization to adherens junction(GO:0071896) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.3 GO:0072719 cellular response to cisplatin(GO:0072719)
0.1 0.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 1.6 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 5.9 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.6 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 1.3 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 1.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.8 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.5 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.6 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0007343 egg activation(GO:0007343) regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427)
0.0 0.1 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 3.9 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.5 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 1.2 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.6 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.2 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 2.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:1904588 thyroid-stimulating hormone signaling pathway(GO:0038194) cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.5 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.3 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.4 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.4 GO:0090179 regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 1.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.5 GO:0097186 amelogenesis(GO:0097186)
0.0 0.5 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.9 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 2.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0032264 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.4 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.2 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0048793 pronephros development(GO:0048793)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.7 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.0 GO:0032242 regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.6 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.3 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.2 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175) protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 1.4 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.4 GO:0003016 respiratory system process(GO:0003016)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0097680 cellular hyperosmotic salinity response(GO:0071475) double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.3 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.9 GO:0042825 TAP complex(GO:0042825)
0.3 2.1 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.2 GO:0031262 Ndc80 complex(GO:0031262)
0.2 4.1 GO:0005861 troponin complex(GO:0005861)
0.1 0.4 GO:0071159 NF-kappaB complex(GO:0071159)
0.1 0.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.3 GO:0097444 spine apparatus(GO:0097444)
0.1 0.5 GO:0001652 granular component(GO:0001652)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.1 1.3 GO:0032433 filopodium tip(GO:0032433)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.2 GO:1990923 PET complex(GO:1990923)
0.1 0.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.6 GO:0045179 apical cortex(GO:0045179)
0.0 1.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 2.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 4.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.6 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 2.1 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0038201 TOR complex(GO:0038201)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 1.7 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.4 1.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.3 1.4 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.3 4.0 GO:0031014 troponin T binding(GO:0031014)
0.3 1.9 GO:0046979 TAP2 binding(GO:0046979)
0.2 0.7 GO:0004766 spermidine synthase activity(GO:0004766)
0.2 1.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 0.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 1.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.2 4.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 0.4 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 0.6 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.5 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 1.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 1.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.6 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.3 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.2 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 1.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.2 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.1 1.6 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.3 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.6 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.5 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 1.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.9 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.3 GO:0005119 smoothened binding(GO:0005119)
0.1 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.3 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 5.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.1 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.6 GO:0004568 chitinase activity(GO:0004568)
0.0 1.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.1 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 1.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 1.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 1.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.8 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID SHP2 PATHWAY SHP2 signaling
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 6.6 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 4.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 1.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis