Project
Inflammatory response time course, HUVEC (Wada et al., 2009)
Navigation
Downloads
Results for CUX2
Z-value: 0.91
Motif logo
Transcription factors associated with CUX2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CUX2 | hg19_v2_chr12_+_111471828_111471975 | 0.05 | 8.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr21_+_42792442 Show fit | 2.86 |
ENST00000398600.2
|
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) |
|
| chr3_-_79068594 Show fit | 1.97 |
ENST00000436010.2
|
roundabout, axon guidance receptor, homolog 1 (Drosophila) |
|
| chr7_-_92777606 Show fit | 1.75 |
ENST00000437805.1
ENST00000446959.1 ENST00000439952.1 ENST00000414791.1 ENST00000446033.1 ENST00000411955.1 ENST00000318238.4 |
sterile alpha motif domain containing 9-like |
|
| chr16_-_28634874 Show fit | 1.10 |
ENST00000395609.1
ENST00000350842.4 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
|
| chr8_+_54764346 Show fit | 1.10 |
ENST00000297313.3
ENST00000344277.6 |
regulator of G-protein signaling 20 |
|
| chr4_-_70518941 Show fit | 1.07 |
ENST00000286604.4
ENST00000505512.1 ENST00000514019.1 |
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus |
|
| chr6_-_11779014 Show fit | 0.95 |
ENST00000229583.5
|
androgen-dependent TFPI-regulating protein |
|
| chr11_+_19799327 Show fit | 0.95 |
ENST00000540292.1
|
neuron navigator 2 |
|
| chr22_-_36556821 Show fit | 0.95 |
ENST00000531095.1
ENST00000397293.2 ENST00000349314.2 |
apolipoprotein L, 3 |
|
| chr6_+_127898312 Show fit | 0.93 |
ENST00000329722.7
|
chromosome 6 open reading frame 58 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CUX2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.0 | GO:0003374 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
| 0.7 | 2.0 | GO:0021827 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
| 0.2 | 1.9 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.1 | 1.5 | GO:0036315 | cellular response to sterol(GO:0036315) |
| 0.0 | 1.5 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 1.2 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.4 | 1.1 | GO:0048597 | B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) |
| 0.1 | 1.1 | GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) |
| 0.0 | 1.1 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.0 | 0.9 | GO:0030574 | collagen catabolic process(GO:0030574) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 1.1 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 1.1 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 0.9 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 0.8 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 0.8 | GO:0090665 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 0.8 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.8 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.7 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.1 | 0.6 | GO:0005579 | membrane attack complex(GO:0005579) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 1.5 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 1.3 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.2 | 1.1 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294) |
| 0.1 | 1.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.3 | 1.0 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.2 | 0.8 | GO:0038047 | beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047) |
| 0.1 | 0.8 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 0.8 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.1 | 0.8 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.1 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 1.1 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 0.8 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.0 | 0.7 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.5 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 0.3 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.2 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.7 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 2.0 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 1.6 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.1 | 1.5 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 1.5 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.2 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 1.1 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 1.1 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 1.1 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 1.0 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |