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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for CUX2

Z-value: 0.91

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Transcription factors associated with CUX2

Gene Symbol Gene ID Gene Info
CUX2
ENSG00000111249.9 cut like homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CUX2hg19_v2_chr12_+_111471828_1114719750.058.3e-01Click!

Activity profile of CUX2 motif

Sorted Z-values of CUX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_42792442 2.86 ENST00000398600.2
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr3_-_79068594 1.97 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr7_-_92777606 1.75 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr16_-_28634874 1.10 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr8_+_54764346 1.10 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr4_-_70518941 1.07 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr6_-_11779014 0.95 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr11_+_19799327 0.95 ENST00000540292.1
NAV2
neuron navigator 2
chr22_-_36556821 0.95 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3
apolipoprotein L, 3
chr6_+_127898312 0.93 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr1_-_151804314 0.92 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr11_-_102651343 0.91 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr20_+_58515417 0.87 ENST00000360816.3
FAM217B
family with sequence similarity 217, member B
chr8_+_77593474 0.86 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr1_-_186649543 0.84 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr11_+_134144139 0.82 ENST00000389887.5
GLB1L3
galactosidase, beta 1-like 3
chr11_-_89653576 0.81 ENST00000420869.1
TRIM49D1
tripartite motif containing 49D1
chr1_+_12976450 0.81 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr8_+_77593448 0.79 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr6_-_11779174 0.79 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr2_-_89513402 0.77 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr6_-_11779403 0.77 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr5_-_135290705 0.76 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr2_-_220264703 0.74 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr12_-_91573132 0.74 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr17_-_3595181 0.72 ENST00000552050.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr5_-_41261540 0.69 ENST00000263413.3
C6
complement component 6
chr3_+_25831567 0.69 ENST00000280701.3
ENST00000420173.2
OXSM
3-oxoacyl-ACP synthase, mitochondrial
chr12_+_131438443 0.69 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr5_-_43397184 0.67 ENST00000513525.1
CCL28
chemokine (C-C motif) ligand 28
chr9_-_100881466 0.67 ENST00000341469.2
ENST00000342043.3
ENST00000375098.3
TRIM14
tripartite motif containing 14
chr4_-_70080449 0.66 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr10_+_114135952 0.66 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr2_+_103035102 0.65 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr18_+_616672 0.65 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr12_-_10151773 0.65 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr12_-_76817036 0.63 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr20_-_58515344 0.62 ENST00000370996.3
PPP1R3D
protein phosphatase 1, regulatory subunit 3D
chr6_+_46761118 0.61 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr1_-_151804222 0.60 ENST00000392697.3
RORC
RAR-related orphan receptor C
chr3_-_112693865 0.58 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200R1
CD200 receptor 1
chr8_-_62559366 0.58 ENST00000522919.1
ASPH
aspartate beta-hydroxylase
chr6_-_33547975 0.58 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr1_-_89736434 0.58 ENST00000370459.3
GBP5
guanylate binding protein 5
chr4_-_70826725 0.57 ENST00000353151.3
CSN2
casein beta
chr6_-_33548006 0.57 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr6_-_119031228 0.57 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr19_-_4535233 0.56 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr2_+_102953608 0.56 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr9_+_96846740 0.55 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr11_-_35440579 0.55 ENST00000606205.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_133874577 0.54 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr19_+_46003056 0.54 ENST00000401593.1
ENST00000396736.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr17_+_41132564 0.53 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr18_-_19994830 0.53 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr12_-_71182695 0.52 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr11_+_55029628 0.52 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr16_+_33204156 0.51 ENST00000398667.4
TP53TG3C
TP53 target 3C
chr11_+_60467047 0.51 ENST00000300226.2
MS4A8
membrane-spanning 4-domains, subfamily A, member 8
chr5_-_115910630 0.50 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr17_-_39526052 0.50 ENST00000251646.3
KRT33B
keratin 33B
chrX_+_9431324 0.49 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr21_+_43619796 0.48 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr19_+_44645700 0.48 ENST00000592437.1
ZNF234
zinc finger protein 234
chr10_+_90424196 0.48 ENST00000394375.3
ENST00000608620.1
ENST00000238983.4
ENST00000355843.2
LIPF
lipase, gastric
chr2_+_102456277 0.47 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chrX_+_152599604 0.46 ENST00000370251.3
ENST00000421401.3
ZNF275
zinc finger protein 275
chr10_-_121296045 0.45 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr19_-_22379753 0.45 ENST00000397121.2
ZNF676
zinc finger protein 676
chr12_-_43833515 0.45 ENST00000549670.1
ENST00000395541.2
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr22_+_51176624 0.44 ENST00000216139.5
ENST00000529621.1
ACR
acrosin
chr1_+_104159999 0.44 ENST00000414303.2
ENST00000423678.1
AMY2A
amylase, alpha 2A (pancreatic)
chr19_+_15904761 0.43 ENST00000308940.8
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr17_+_7461613 0.43 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr14_+_74058410 0.43 ENST00000326303.4
ACOT4
acyl-CoA thioesterase 4
chr10_+_13141585 0.43 ENST00000378764.2
OPTN
optineurin
chr2_-_152830479 0.42 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr22_+_18721427 0.42 ENST00000342888.3
AC008132.1
Uncharacterized protein
chr17_-_64216748 0.42 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr11_-_62911693 0.41 ENST00000417740.1
ENST00000326192.5
SLC22A24
solute carrier family 22, member 24
chr4_-_34041504 0.41 ENST00000512581.1
ENST00000505018.1
RP11-79E3.3
RP11-79E3.3
chr11_+_82612740 0.41 ENST00000524921.1
ENST00000528759.1
ENST00000525361.1
ENST00000430323.2
ENST00000533655.1
ENST00000532764.1
ENST00000532589.1
ENST00000525388.1
C11orf82
chromosome 11 open reading frame 82
chr2_+_27255806 0.40 ENST00000238788.9
ENST00000404032.3
TMEM214
transmembrane protein 214
chr11_-_7818520 0.40 ENST00000329434.2
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chr22_+_30821732 0.40 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr1_-_89591749 0.40 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr5_+_140529630 0.40 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr8_+_94241867 0.40 ENST00000598428.1
AC016885.1
Uncharacterized protein
chr19_-_47287990 0.40 ENST00000593713.1
ENST00000598022.1
ENST00000434726.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr16_+_30064411 0.39 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr13_+_73629107 0.38 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr5_-_58882219 0.38 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_75024903 0.38 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chr1_-_162346657 0.38 ENST00000367935.5
C1orf111
chromosome 1 open reading frame 111
chr8_-_134072593 0.38 ENST00000427060.2
SLA
Src-like-adaptor
chr12_+_26348429 0.37 ENST00000242729.2
SSPN
sarcospan
chr12_+_6833237 0.37 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COPS7A
COP9 signalosome subunit 7A
chr7_+_148844516 0.37 ENST00000420008.2
ENST00000475153.1
ZNF398
zinc finger protein 398
chr4_+_70894130 0.37 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr17_-_79876010 0.37 ENST00000328666.6
SIRT7
sirtuin 7
chr16_+_30064444 0.36 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA
aldolase A, fructose-bisphosphate
chr3_+_181429704 0.36 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr6_+_154360553 0.36 ENST00000452687.2
OPRM1
opioid receptor, mu 1
chr20_+_62492566 0.36 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chr3_+_130650738 0.36 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr4_-_70505358 0.35 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UGT2A2
UDP glucuronosyltransferase 2 family, polypeptide A2
chr15_-_89089860 0.35 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
DET1
de-etiolated homolog 1 (Arabidopsis)
chr8_+_104892639 0.35 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr2_-_89442621 0.35 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr1_+_196743912 0.35 ENST00000367425.4
CFHR3
complement factor H-related 3
chr12_-_87232644 0.34 ENST00000549405.2
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr4_+_71263599 0.34 ENST00000399575.2
PROL1
proline rich, lacrimal 1
chrX_-_11284095 0.34 ENST00000303025.6
ENST00000534860.1
ARHGAP6
Rho GTPase activating protein 6
chr19_+_58570605 0.34 ENST00000359978.6
ENST00000401053.4
ENST00000439855.2
ENST00000313434.5
ENST00000511556.1
ENST00000506786.1
ZNF135
zinc finger protein 135
chr22_+_24198890 0.34 ENST00000345044.6
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr17_-_64225508 0.33 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr11_+_35201826 0.33 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr11_+_62623544 0.33 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr3_-_58563094 0.33 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr12_+_26348246 0.33 ENST00000422622.2
SSPN
sarcospan
chr5_-_74326724 0.33 ENST00000322348.4
GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
chr13_-_46756351 0.33 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr5_-_135701164 0.33 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
TRPC7
transient receptor potential cation channel, subfamily C, member 7
chr12_+_82347498 0.32 ENST00000550506.1
RP11-362A1.1
RP11-362A1.1
chr11_+_12308447 0.32 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr15_+_69307028 0.32 ENST00000388866.3
ENST00000530406.2
NOX5
NADPH oxidase, EF-hand calcium binding domain 5
chr2_-_214016314 0.31 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr10_-_90751038 0.31 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_+_51863433 0.31 ENST00000444293.1
IQCF3
IQ motif containing F3
chr7_-_3214287 0.30 ENST00000404626.3
AC091801.1
LOC392621; Uncharacterized protein
chr14_-_24020858 0.30 ENST00000419474.3
ZFHX2
zinc finger homeobox 2
chr19_+_42301079 0.30 ENST00000596544.1
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr5_+_32788945 0.30 ENST00000326958.1
AC026703.1
AC026703.1
chr6_+_46661575 0.30 ENST00000450697.1
TDRD6
tudor domain containing 6
chr5_-_101834617 0.30 ENST00000513675.1
ENST00000379807.3
SLCO6A1
solute carrier organic anion transporter family, member 6A1
chr16_-_740354 0.30 ENST00000293883.4
WDR24
WD repeat domain 24
chr8_-_18541603 0.30 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr12_+_7052974 0.29 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr11_+_5410607 0.29 ENST00000328611.3
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr11_-_35440796 0.29 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr19_+_56713670 0.28 ENST00000534327.1
ZSCAN5C
zinc finger and SCAN domain containing 5C
chr7_+_142458507 0.28 ENST00000492062.1
PRSS1
protease, serine, 1 (trypsin 1)
chr2_-_136743039 0.28 ENST00000537273.1
DARS
aspartyl-tRNA synthetase
chr11_+_67219867 0.28 ENST00000438189.2
CABP4
calcium binding protein 4
chr11_+_22689648 0.28 ENST00000278187.3
GAS2
growth arrest-specific 2
chr1_+_237205476 0.27 ENST00000366574.2
RYR2
ryanodine receptor 2 (cardiac)
chr16_-_740419 0.27 ENST00000248142.6
WDR24
WD repeat domain 24
chr3_-_186262166 0.27 ENST00000307944.5
CRYGS
crystallin, gamma S
chr2_+_89986318 0.27 ENST00000491977.1
IGKV2D-29
immunoglobulin kappa variable 2D-29
chr19_+_507299 0.27 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr5_+_121465207 0.27 ENST00000296600.4
ZNF474
zinc finger protein 474
chrX_+_56100757 0.27 ENST00000433279.1
AL353698.1
Uncharacterized protein
chr4_-_143226979 0.26 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr8_-_87755878 0.26 ENST00000320005.5
CNGB3
cyclic nucleotide gated channel beta 3
chr15_-_38519066 0.26 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr7_-_26578407 0.26 ENST00000242109.3
KIAA0087
KIAA0087
chr8_+_125954281 0.26 ENST00000510897.2
ENST00000533286.1
LINC00964
long intergenic non-protein coding RNA 964
chr17_-_34890665 0.26 ENST00000586007.1
MYO19
myosin XIX
chr6_+_79577189 0.26 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr3_-_11685345 0.26 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr17_+_7942335 0.26 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
ALOX15B
arachidonate 15-lipoxygenase, type B
chr3_+_197687071 0.25 ENST00000482695.1
ENST00000330198.4
ENST00000419117.1
ENST00000420910.2
ENST00000332636.5
LMLN
leishmanolysin-like (metallopeptidase M8 family)
chr9_+_35673853 0.25 ENST00000378357.4
CA9
carbonic anhydrase IX
chr1_-_23340400 0.25 ENST00000440767.2
C1orf234
chromosome 1 open reading frame 234
chr17_+_3118915 0.25 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr2_-_152830441 0.25 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chrX_-_77225135 0.25 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr13_-_36920420 0.25 ENST00000438666.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr6_+_26273144 0.25 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr17_-_2996290 0.25 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr7_+_151653464 0.25 ENST00000431418.2
ENST00000392800.2
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr1_-_198990166 0.25 ENST00000427439.1
RP11-16L9.3
RP11-16L9.3
chr9_+_95726243 0.25 ENST00000416701.2
FGD3
FYVE, RhoGEF and PH domain containing 3
chr4_-_100356551 0.25 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_+_157330081 0.25 ENST00000409674.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr12_-_11422630 0.25 ENST00000381842.3
ENST00000538488.1
PRB3
proline-rich protein BstNI subfamily 3
chr1_+_225600404 0.24 ENST00000366845.2
AC092811.1
AC092811.1
chr19_+_42300548 0.24 ENST00000344550.4
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr1_+_89246647 0.24 ENST00000544045.1
PKN2
protein kinase N2
chr6_-_32160622 0.24 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr1_+_44870866 0.24 ENST00000355387.2
ENST00000361799.2
RNF220
ring finger protein 220
chr19_+_35417939 0.24 ENST00000601142.1
ENST00000426813.2
ZNF30
zinc finger protein 30
chr7_-_121944491 0.24 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr16_-_4817129 0.24 ENST00000545009.1
ENST00000219478.6
ZNF500
zinc finger protein 500
chr2_+_102413726 0.24 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr4_-_139051839 0.24 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
LINC00616
long intergenic non-protein coding RNA 616
chr6_-_27880174 0.23 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr6_+_154360476 0.23 ENST00000428397.2
OPRM1
opioid receptor, mu 1
chrX_+_49363665 0.23 ENST00000381700.6
GAGE1
G antigen 1
chr1_+_196743943 0.23 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr10_+_124670121 0.23 ENST00000368894.1
FAM24A
family with sequence similarity 24, member A
chr1_+_13910194 0.23 ENST00000376057.4
ENST00000510906.1
PDPN
podoplanin
chr15_+_64680003 0.22 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr5_-_78365437 0.22 ENST00000380311.4
ENST00000540686.1
ENST00000255189.3
DMGDH
dimethylglycine dehydrogenase
chr13_-_86373536 0.22 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr3_-_194072019 0.22 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chrX_-_47489244 0.22 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr13_-_62001982 0.22 ENST00000409186.1
PCDH20
protocadherin 20
chr3_-_150690786 0.22 ENST00000327047.1
CLRN1
clarin 1
chr2_+_234959376 0.22 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.4 1.1 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 0.8 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.3 3.0 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2 0.8 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.2 0.6 GO:1903487 regulation of lactation(GO:1903487)
0.2 0.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 1.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.7 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1 0.4 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.5 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.1 0.3 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.1 0.4 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.8 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.4 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.7 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.3 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.1 0.6 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.3 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.7 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.2 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.8 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 0.3 GO:0060356 leucine import(GO:0060356)
0.1 0.4 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.4 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 1.5 GO:0036315 cellular response to sterol(GO:0036315)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.3 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 1.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:2000143 negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.4 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.2 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.7 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.3 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.3 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.4 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.1 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 1.2 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.7 GO:0030220 platelet formation(GO:0030220)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.7 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.6 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 1.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.3 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0043092 L-amino acid import(GO:0043092)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.3 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.3 GO:0071748 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.6 GO:0042587 glycogen granule(GO:0042587)
0.1 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.8 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.8 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.2 0.6 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 0.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 1.5 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 1.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 1.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0016160 amylase activity(GO:0016160)
0.1 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.6 GO:0035473 lipase binding(GO:0035473)
0.1 0.4 GO:0004040 amidase activity(GO:0004040)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.7 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.8 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 1.3 GO:0051400 BH domain binding(GO:0051400)
0.1 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.2 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.2 GO:0030395 lactose binding(GO:0030395)
0.1 0.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.7 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.6 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.5 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0015216 purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 2.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 2.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis