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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for DBP

Z-value: 0.91

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Transcription factors associated with DBP

Gene Symbol Gene ID Gene Info
DBP
ENSG00000105516.6 D-box binding PAR bZIP transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DBPhg19_v2_chr19_-_49140692_491407090.404.8e-02Click!

Activity profile of DBP motif

Sorted Z-values of DBP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_61547405 3.50 ENST00000371189.4
NFIA
nuclear factor I/A
chr3_+_141105705 2.56 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr1_+_114522049 2.12 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr3_-_52479043 2.05 ENST00000231721.2
ENST00000475739.1
SEMA3G
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr1_+_61547894 2.02 ENST00000403491.3
NFIA
nuclear factor I/A
chr4_-_186732048 1.93 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr4_-_16900410 1.85 ENST00000304523.5
LDB2
LIM domain binding 2
chr4_-_16900184 1.85 ENST00000515064.1
LDB2
LIM domain binding 2
chr4_-_16900217 1.84 ENST00000441778.2
LDB2
LIM domain binding 2
chr4_-_16900242 1.83 ENST00000502640.1
ENST00000506732.1
LDB2
LIM domain binding 2
chr1_+_82266053 1.75 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chrX_+_10031499 1.67 ENST00000454666.1
WWC3
WWC family member 3
chr14_+_61788429 1.58 ENST00000332981.5
PRKCH
protein kinase C, eta
chr9_+_2158443 1.54 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_-_22550815 1.53 ENST00000317216.2
EGR3
early growth response 3
chr1_+_84609944 1.51 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_+_35484053 1.46 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
CREM
cAMP responsive element modulator
chr13_-_99667960 1.43 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr21_+_17791648 1.41 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr14_-_92413353 1.41 ENST00000556154.1
FBLN5
fibulin 5
chr9_+_2158485 1.39 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr21_+_17791838 1.38 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr5_-_111091948 1.31 ENST00000447165.2
NREP
neuronal regeneration related protein
chr13_+_97928395 1.29 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr13_-_114843416 1.29 ENST00000389544.4
RASA3
RAS p21 protein activator 3
chr8_-_80993010 1.27 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr1_+_61548225 1.19 ENST00000371187.3
NFIA
nuclear factor I/A
chr7_-_129592471 1.02 ENST00000473814.2
ENST00000490974.1
UBE2H
ubiquitin-conjugating enzyme E2H
chr7_+_13141097 0.99 ENST00000411542.1
AC011288.2
AC011288.2
chr9_+_82187630 0.95 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr9_+_82187487 0.94 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr20_-_23066953 0.92 ENST00000246006.4
CD93
CD93 molecule
chr18_-_22932080 0.92 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521
zinc finger protein 521
chr1_-_85870177 0.91 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr8_-_17533838 0.86 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr14_+_24590560 0.83 ENST00000558325.1
RP11-468E2.6
RP11-468E2.6
chr3_+_141043050 0.81 ENST00000509842.1
ZBTB38
zinc finger and BTB domain containing 38
chr3_+_141106458 0.76 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chrX_-_24045303 0.76 ENST00000328046.8
KLHL15
kelch-like family member 15
chr10_-_64576105 0.74 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr21_-_40033618 0.74 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr13_+_97874574 0.71 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr2_+_210517895 0.68 ENST00000447185.1
MAP2
microtubule-associated protein 2
chrX_+_149531524 0.67 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr7_-_121784285 0.67 ENST00000417368.2
AASS
aminoadipate-semialdehyde synthase
chr3_+_137483579 0.66 ENST00000306087.1
SOX14
SRY (sex determining region Y)-box 14
chr8_-_6420565 0.66 ENST00000338312.6
ANGPT2
angiopoietin 2
chr3_-_149375783 0.66 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr9_-_13165457 0.65 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr3_-_185538849 0.63 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr6_-_117747015 0.62 ENST00000368508.3
ENST00000368507.3
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr2_-_208031542 0.62 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr19_+_10765699 0.61 ENST00000590009.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr5_+_73109339 0.61 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chrX_-_125686784 0.58 ENST00000371126.1
DCAF12L1
DDB1 and CUL4 associated factor 12-like 1
chr8_-_6420759 0.58 ENST00000523120.1
ANGPT2
angiopoietin 2
chr14_+_22538811 0.58 ENST00000390450.3
TRAV22
T cell receptor alpha variable 22
chr3_+_109128837 0.57 ENST00000497996.1
RP11-702L6.4
RP11-702L6.4
chr17_+_2240775 0.56 ENST00000268989.3
ENST00000426855.2
SGSM2
small G protein signaling modulator 2
chr8_+_68864330 0.56 ENST00000288368.4
PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr12_-_89746173 0.55 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr7_-_37026108 0.54 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr17_+_67498538 0.53 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_-_216257849 0.53 ENST00000456923.1
FN1
fibronectin 1
chr17_+_4613918 0.52 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2
arrestin, beta 2
chr9_+_82186872 0.51 ENST00000376544.3
ENST00000376520.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chrX_+_28605516 0.51 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr12_-_56236734 0.50 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chr3_+_152017360 0.50 ENST00000485910.1
ENST00000463374.1
MBNL1
muscleblind-like splicing regulator 1
chr17_+_4613776 0.49 ENST00000269260.2
ARRB2
arrestin, beta 2
chr8_+_134125727 0.49 ENST00000521107.1
TG
thyroglobulin
chr4_-_185395672 0.48 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr11_-_66445219 0.46 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B
RNA binding motif protein 4B
chr8_-_6420777 0.45 ENST00000415216.1
ANGPT2
angiopoietin 2
chr8_-_6420930 0.45 ENST00000325203.5
ANGPT2
angiopoietin 2
chr20_+_11898507 0.44 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr6_+_143929307 0.44 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr7_+_35756186 0.43 ENST00000430518.1
AC018647.3
AC018647.3
chr7_+_35756092 0.43 ENST00000458087.3
AC018647.3
AC018647.3
chr2_+_210444748 0.43 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr17_+_28705921 0.42 ENST00000225719.4
CPD
carboxypeptidase D
chr17_+_48624450 0.41 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20
spermatogenesis associated 20
chr9_+_116263778 0.40 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr11_-_62414070 0.40 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr3_+_44607051 0.39 ENST00000419137.1
RP11-944L7.5
Zinc finger protein with KRAB and SCAN domains 7
chrX_-_10851762 0.39 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr19_-_42806919 0.38 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr6_+_26251835 0.38 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr20_+_43935474 0.37 ENST00000372743.1
ENST00000372741.3
ENST00000343694.3
RBPJL
recombination signal binding protein for immunoglobulin kappa J region-like
chr2_+_210444142 0.37 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr4_+_81118647 0.37 ENST00000415738.2
PRDM8
PR domain containing 8
chr15_+_58702742 0.37 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr4_+_106473768 0.36 ENST00000265154.2
ENST00000420470.2
ARHGEF38
Rho guanine nucleotide exchange factor (GEF) 38
chr17_+_26369865 0.36 ENST00000582037.1
NLK
nemo-like kinase
chr1_+_28764653 0.35 ENST00000373836.3
PHACTR4
phosphatase and actin regulator 4
chr3_-_112564797 0.34 ENST00000398214.1
ENST00000448932.1
CD200R1L
CD200 receptor 1-like
chr10_-_65028817 0.34 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr1_-_227505289 0.33 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr6_+_53976235 0.33 ENST00000502396.1
ENST00000358276.5
MLIP
muscular LMNA-interacting protein
chr3_+_182511266 0.33 ENST00000323116.5
ENST00000493826.1
ATP11B
ATPase, class VI, type 11B
chr3_+_152017181 0.32 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chr8_-_29120580 0.32 ENST00000524189.1
KIF13B
kinesin family member 13B
chr2_-_208031943 0.32 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr10_-_65028938 0.31 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chrX_+_129473859 0.31 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr17_+_2240916 0.31 ENST00000574563.1
SGSM2
small G protein signaling modulator 2
chr12_-_92536433 0.31 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr6_-_56819385 0.31 ENST00000370754.5
ENST00000449297.2
DST
dystonin
chr5_+_61874562 0.31 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chrX_-_83442915 0.30 ENST00000262752.2
ENST00000543399.1
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr5_+_179233376 0.29 ENST00000376929.3
ENST00000514093.1
SQSTM1
sequestosome 1
chr9_+_135854091 0.29 ENST00000450530.1
ENST00000534944.1
GFI1B
growth factor independent 1B transcription repressor
chr2_-_111291587 0.29 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr22_+_38201114 0.29 ENST00000340857.2
H1F0
H1 histone family, member 0
chr13_-_41593425 0.28 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_+_135011731 0.28 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr10_-_29811456 0.27 ENST00000535393.1
SVIL
supervillin
chr1_+_153700518 0.27 ENST00000318967.2
ENST00000456435.1
ENST00000435409.2
INTS3
integrator complex subunit 3
chr3_-_114343039 0.27 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chrX_+_129473916 0.27 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr5_+_140588269 0.26 ENST00000541609.1
ENST00000239450.2
PCDHB12
protocadherin beta 12
chr10_+_695888 0.25 ENST00000441152.2
PRR26
proline rich 26
chr1_+_57320437 0.25 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr4_-_116034979 0.24 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr8_+_42196000 0.24 ENST00000518925.1
ENST00000538005.1
POLB
polymerase (DNA directed), beta
chr3_+_123813509 0.24 ENST00000460856.1
ENST00000240874.3
KALRN
kalirin, RhoGEF kinase
chr12_-_6483969 0.24 ENST00000396966.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chrX_+_99839799 0.24 ENST00000373031.4
TNMD
tenomodulin
chr8_+_42195972 0.23 ENST00000532157.1
ENST00000265421.4
ENST00000520008.1
POLB
polymerase (DNA directed), beta
chr17_-_39646116 0.23 ENST00000328119.6
KRT36
keratin 36
chr8_+_107738343 0.22 ENST00000521592.1
OXR1
oxidation resistance 1
chr17_+_7487146 0.22 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr17_+_42429493 0.22 ENST00000586242.1
GRN
granulin
chrX_-_100641155 0.22 ENST00000372880.1
ENST00000308731.7
BTK
Bruton agammaglobulinemia tyrosine kinase
chr17_-_27333311 0.21 ENST00000317338.12
ENST00000585644.1
SEZ6
seizure related 6 homolog (mouse)
chr17_-_34195889 0.21 ENST00000311880.2
C17orf66
chromosome 17 open reading frame 66
chr14_+_58765103 0.21 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr6_+_88054530 0.21 ENST00000388923.4
C6orf163
chromosome 6 open reading frame 163
chr17_-_34195862 0.21 ENST00000592980.1
ENST00000587626.1
C17orf66
chromosome 17 open reading frame 66
chr19_+_13134772 0.21 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr10_+_115511213 0.20 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr17_-_27332931 0.20 ENST00000442608.3
ENST00000335960.6
SEZ6
seizure related 6 homolog (mouse)
chrX_-_111923145 0.20 ENST00000371968.3
ENST00000536453.1
LHFPL1
lipoma HMGIC fusion partner-like 1
chr1_+_155051305 0.20 ENST00000368408.3
EFNA3
ephrin-A3
chr17_+_29664830 0.20 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr11_+_112832133 0.20 ENST00000524665.1
NCAM1
neural cell adhesion molecule 1
chr2_+_95963052 0.19 ENST00000295225.5
KCNIP3
Kv channel interacting protein 3, calsenilin
chr9_+_135457530 0.19 ENST00000263610.2
BARHL1
BarH-like homeobox 1
chr2_-_118943930 0.18 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
AC093901.1
chr6_+_44194762 0.18 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr2_+_191002486 0.18 ENST00000396974.2
C2orf88
chromosome 2 open reading frame 88
chr18_-_21891460 0.18 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chrX_+_134654540 0.18 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr7_-_22234381 0.18 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr19_+_19496728 0.17 ENST00000537887.1
ENST00000417582.2
GATAD2A
GATA zinc finger domain containing 2A
chr14_+_23654525 0.17 ENST00000399910.1
ENST00000492621.1
C14orf164
chromosome 14 open reading frame 164
chr11_+_102980251 0.17 ENST00000334267.7
ENST00000398093.3
DYNC2H1
dynein, cytoplasmic 2, heavy chain 1
chr17_-_27333163 0.17 ENST00000360295.9
SEZ6
seizure related 6 homolog (mouse)
chr1_+_154229547 0.17 ENST00000428595.1
UBAP2L
ubiquitin associated protein 2-like
chr3_-_48471454 0.17 ENST00000296440.6
ENST00000448774.2
PLXNB1
plexin B1
chr16_+_29789561 0.16 ENST00000400752.4
ZG16
zymogen granule protein 16
chr6_-_31514333 0.15 ENST00000376151.4
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chrX_+_16141667 0.15 ENST00000380289.2
GRPR
gastrin-releasing peptide receptor
chr3_+_123813543 0.14 ENST00000360013.3
KALRN
kalirin, RhoGEF kinase
chr2_+_171571827 0.14 ENST00000375281.3
SP5
Sp5 transcription factor
chr6_-_31514516 0.14 ENST00000303892.5
ENST00000483251.1
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr11_-_31832581 0.14 ENST00000379111.2
PAX6
paired box 6
chr8_-_120685608 0.13 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr12_-_120765565 0.13 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr16_+_78056412 0.13 ENST00000299642.4
ENST00000575655.1
CLEC3A
C-type lectin domain family 3, member A
chrX_-_19817869 0.13 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr7_-_144107320 0.13 ENST00000483238.1
ENST00000467773.1
NOBOX
NOBOX oogenesis homeobox
chr8_-_102803163 0.13 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr6_+_21593972 0.13 ENST00000244745.1
ENST00000543472.1
SOX4
SRY (sex determining region Y)-box 4
chr7_+_99613212 0.12 ENST00000426572.1
ENST00000535170.1
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr9_-_95186739 0.12 ENST00000375550.4
OMD
osteomodulin
chr17_+_72426891 0.12 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr18_+_22040620 0.12 ENST00000426880.2
HRH4
histamine receptor H4
chr2_-_60780536 0.11 ENST00000538214.1
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr15_+_78632666 0.11 ENST00000299529.6
CRABP1
cellular retinoic acid binding protein 1
chr5_+_32710736 0.11 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr5_-_134735568 0.11 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr5_-_16916624 0.11 ENST00000513882.1
MYO10
myosin X
chr6_-_149806105 0.11 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D
zinc finger CCCH-type containing 12D
chr8_-_54755459 0.11 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr19_-_57988871 0.11 ENST00000596831.1
ENST00000601768.1
ENST00000356584.3
ENST00000600175.1
ENST00000425074.3
ENST00000343280.4
ENST00000427512.2
AC004076.9
ZNF772
Uncharacterized protein
zinc finger protein 772
chrX_+_49644470 0.11 ENST00000508866.2
USP27X
ubiquitin specific peptidase 27, X-linked
chr12_-_62586543 0.11 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr1_+_203734296 0.11 ENST00000442561.2
ENST00000367217.5
LAX1
lymphocyte transmembrane adaptor 1
chr11_+_92085707 0.11 ENST00000525166.1
FAT3
FAT atypical cadherin 3
chr15_+_69854027 0.10 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr11_-_122931881 0.10 ENST00000526110.1
ENST00000227378.3
HSPA8
heat shock 70kDa protein 8
chr8_+_19796381 0.10 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL
lipoprotein lipase
chr8_-_114449112 0.10 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr11_+_121461097 0.10 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr5_+_66300446 0.09 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr10_-_79397202 0.09 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_-_33168391 0.09 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr6_-_94129244 0.08 ENST00000369303.4
ENST00000369297.1
EPHA7
EPH receptor A7
chr15_-_40600111 0.08 ENST00000543785.2
ENST00000260402.3
PLCB2
phospholipase C, beta 2

Network of associatons between targets according to the STRING database.

First level regulatory network of DBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.2 0.7 GO:0021571 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 6.7 GO:0072189 ureter development(GO:0072189)
0.2 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 7.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 0.2 GO:0071226 response to molecule of fungal origin(GO:0002238) cellular response to molecule of fungal origin(GO:0071226)
0.2 1.5 GO:0097338 response to clozapine(GO:0097338)
0.2 1.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.2 1.5 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.2 0.5 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 0.5 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 0.7 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 1.6 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2 0.5 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.2 1.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.8 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.6 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.7 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.3 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.5 GO:0015705 iodide transport(GO:0015705)
0.1 0.9 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 1.9 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 1.4 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.1 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.7 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.0 2.3 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 1.3 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 1.0 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 1.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:1905247 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 3.1 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 1.3 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 2.5 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.4 GO:0071953 elastic fiber(GO:0071953)
0.1 3.0 GO:0071564 npBAF complex(GO:0071564)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.1 1.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 4.3 GO:0072562 blood microparticle(GO:0072562)
0.0 9.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.4 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.0 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.3 1.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.9 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.1 4.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 1.3 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 3.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.7 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 7.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 1.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 3.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 1.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 2.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.0 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation