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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for DBX2_HLX

Z-value: 0.62

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Transcription factors associated with DBX2_HLX

Gene Symbol Gene ID Gene Info
DBX2
ENSG00000185610.6 developing brain homeobox 2
HLX
ENSG00000136630.11 H2.0 like homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HLXhg19_v2_chr1_+_221051699_2210516990.442.6e-02Click!

Activity profile of DBX2_HLX motif

Sorted Z-values of DBX2_HLX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_156587853 4.35 ENST00000506455.1
ENST00000511108.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr8_+_98900132 1.80 ENST00000520016.1
MATN2
matrilin 2
chr4_+_41540160 1.60 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr1_+_84630645 1.53 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_76540386 1.44 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr12_-_10978957 1.21 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr4_+_156587979 1.19 ENST00000511507.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr11_-_63376013 1.08 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr20_-_33735070 1.05 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr6_+_132455526 1.00 ENST00000443303.1
LINC01013
long intergenic non-protein coding RNA 1013
chr3_-_18480260 0.97 ENST00000454909.2
SATB1
SATB homeobox 1
chr6_-_76072719 0.95 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr6_-_52859046 0.92 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chrX_+_77166172 0.90 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr14_-_54423529 0.86 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr6_+_132455118 0.85 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr3_-_141719195 0.81 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr9_+_75766763 0.79 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr4_-_140201333 0.79 ENST00000398955.1
MGARP
mitochondria-localized glutamic acid-rich protein
chr3_+_138340049 0.78 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr19_+_50016610 0.76 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr22_-_29107919 0.75 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr9_+_71944241 0.74 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr1_+_221051699 0.73 ENST00000366903.6
HLX
H2.0-like homeobox
chr7_+_107224364 0.73 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr4_-_110723194 0.72 ENST00000394635.3
CFI
complement factor I
chr4_-_90757364 0.71 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr1_-_92371839 0.71 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr19_-_58864848 0.67 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr12_-_10022735 0.66 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr7_+_138943265 0.66 ENST00000483726.1
UBN2
ubinuclein 2
chr8_-_93115445 0.64 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_116444371 0.64 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr8_+_97597148 0.63 ENST00000521590.1
SDC2
syndecan 2
chr1_-_160924589 0.62 ENST00000368029.3
ITLN2
intelectin 2
chr4_-_110723134 0.62 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr14_-_78083112 0.62 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr5_+_55149150 0.61 ENST00000297015.3
IL31RA
interleukin 31 receptor A
chr1_+_81771806 0.61 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr10_+_5135981 0.60 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr2_-_183106641 0.60 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr12_-_12503156 0.59 ENST00000543314.1
ENST00000396349.3
MANSC1
MANSC domain containing 1
chr10_+_35484793 0.58 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr7_+_130126165 0.57 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr7_+_130126012 0.54 ENST00000341441.5
MEST
mesoderm specific transcript
chr19_+_13842559 0.53 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chr9_+_34652164 0.52 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chrX_+_55744228 0.52 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr19_+_50016411 0.51 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr17_+_67498538 0.50 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr9_+_2015335 0.49 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_145782358 0.49 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr7_+_99717230 0.48 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr1_+_196788887 0.48 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr10_+_32873190 0.48 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr4_-_163085107 0.47 ENST00000379164.4
FSTL5
follistatin-like 5
chr16_-_30122717 0.47 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr4_-_159080806 0.47 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chrX_+_55744166 0.47 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr6_+_26104104 0.47 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chr16_+_24549014 0.45 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr17_+_61086917 0.45 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr18_+_6834472 0.45 ENST00000581099.1
ENST00000419673.2
ENST00000531294.1
ARHGAP28
Rho GTPase activating protein 28
chr3_-_141747950 0.44 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr6_-_110501200 0.44 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WASF1
WAS protein family, member 1
chr12_-_10959892 0.43 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr17_+_35851570 0.42 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr2_+_88047606 0.42 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr9_-_5833027 0.40 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr2_+_133874577 0.39 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr19_+_35417798 0.39 ENST00000303586.7
ENST00000439785.1
ENST00000601540.1
ZNF30
zinc finger protein 30
chr14_+_57046500 0.38 ENST00000261556.6
TMEM260
transmembrane protein 260
chr2_+_120687335 0.37 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr13_-_110438914 0.36 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr7_+_116654935 0.36 ENST00000432298.1
ENST00000422922.1
ST7
suppression of tumorigenicity 7
chr18_-_53303123 0.35 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr6_-_112575838 0.34 ENST00000455073.1
LAMA4
laminin, alpha 4
chr15_-_20193370 0.34 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr16_+_81678957 0.33 ENST00000398040.4
CMIP
c-Maf inducing protein
chr5_+_140227048 0.32 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr1_+_196912902 0.32 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr1_-_54411255 0.32 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr6_+_28092338 0.32 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr5_+_95066823 0.31 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr3_-_150996239 0.31 ENST00000309170.3
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr6_-_112575687 0.31 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr7_-_5998714 0.30 ENST00000539903.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr19_-_51920952 0.30 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr4_-_100356551 0.30 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_+_59989918 0.30 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr12_+_60058458 0.30 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr20_-_29978286 0.29 ENST00000376315.2
DEFB119
defensin, beta 119
chr8_+_42396274 0.29 ENST00000438528.3
SMIM19
small integral membrane protein 19
chrX_-_73072534 0.28 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr7_+_13141097 0.28 ENST00000411542.1
AC011288.2
AC011288.2
chr7_-_130080977 0.28 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr2_+_87135076 0.27 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chr2_-_165424973 0.27 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr1_-_21377383 0.27 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr11_-_128894053 0.27 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr6_-_112575758 0.27 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr16_+_33204156 0.27 ENST00000398667.4
TP53TG3C
TP53 target 3C
chr6_+_26087509 0.27 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr5_-_55412774 0.27 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr15_+_75639296 0.27 ENST00000564500.1
ENST00000355059.4
ENST00000566752.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr20_-_25320367 0.26 ENST00000450393.1
ENST00000491682.1
ABHD12
abhydrolase domain containing 12
chr7_+_138915102 0.26 ENST00000486663.1
UBN2
ubinuclein 2
chr13_+_32313658 0.26 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr6_+_29079668 0.25 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr20_+_11008811 0.25 ENST00000537362.1
C20orf187
chromosome 20 open reading frame 187
chr3_+_136649311 0.25 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr6_+_130339710 0.25 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr16_+_15489603 0.25 ENST00000568766.1
ENST00000287594.7
RP11-1021N1.1
MPV17L
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr11_-_102576537 0.24 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr9_-_95166841 0.24 ENST00000262551.4
OGN
osteoglycin
chr2_+_101591314 0.24 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr2_-_58468437 0.24 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chr11_-_121986923 0.24 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr7_-_64023410 0.24 ENST00000447137.2
ZNF680
zinc finger protein 680
chr2_-_179343226 0.24 ENST00000434643.2
FKBP7
FK506 binding protein 7
chr6_-_52859968 0.24 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chr8_+_11666649 0.23 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr7_+_151722712 0.23 ENST00000430044.2
ENST00000431668.1
ENST00000446096.1
ENST00000452146.2
ENST00000423337.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr11_-_2162468 0.23 ENST00000434045.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr12_-_46121554 0.23 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr15_+_25200108 0.23 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr2_-_27712583 0.23 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr10_+_81601114 0.23 ENST00000602967.1
ENST00000429984.3
NUTM2E
NUT family member 2E
chr15_+_25200074 0.23 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr18_+_60206744 0.22 ENST00000586834.1
ZCCHC2
zinc finger, CCHC domain containing 2
chr7_-_64023441 0.22 ENST00000309683.6
ZNF680
zinc finger protein 680
chr17_-_41050716 0.22 ENST00000417193.1
ENST00000301683.3
ENST00000436546.1
ENST00000431109.2
LINC00671
long intergenic non-protein coding RNA 671
chr14_-_72458326 0.22 ENST00000542853.1
AC005477.1
AC005477.1
chr9_-_21305312 0.22 ENST00000259555.4
IFNA5
interferon, alpha 5
chr16_-_66584059 0.22 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2
thymidine kinase 2, mitochondrial
chr11_+_49050504 0.22 ENST00000332682.7
TRIM49B
tripartite motif containing 49B
chr6_-_112575912 0.21 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr11_+_22689648 0.21 ENST00000278187.3
GAS2
growth arrest-specific 2
chr6_+_89674246 0.21 ENST00000369474.1
AL079342.1
Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr14_-_106552755 0.21 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr7_+_80275953 0.21 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr3_+_16216137 0.21 ENST00000339732.5
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr2_+_85811525 0.21 ENST00000306384.4
VAMP5
vesicle-associated membrane protein 5
chr1_+_158801095 0.21 ENST00000368141.4
MNDA
myeloid cell nuclear differentiation antigen
chr3_+_138340067 0.21 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr13_+_103459704 0.21 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr1_+_178694300 0.21 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr2_-_191115229 0.21 ENST00000409820.2
ENST00000410045.1
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chrX_+_44703249 0.20 ENST00000339042.4
DUSP21
dual specificity phosphatase 21
chr5_-_111754948 0.20 ENST00000261486.5
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr13_+_24144796 0.20 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr14_-_90085458 0.20 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr9_-_95166884 0.19 ENST00000375561.5
OGN
osteoglycin
chr20_+_11871371 0.19 ENST00000254977.3
BTBD3
BTB (POZ) domain containing 3
chr16_+_14802801 0.19 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr16_-_28937027 0.19 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr17_-_38938786 0.19 ENST00000301656.3
KRT27
keratin 27
chr20_+_11871433 0.19 ENST00000399006.2
ENST00000405977.1
BTBD3
BTB (POZ) domain containing 3
chrX_+_153533275 0.19 ENST00000426989.1
ENST00000426203.1
ENST00000369912.2
TKTL1
transketolase-like 1
chr9_+_105757590 0.18 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr2_+_169312350 0.18 ENST00000305747.6
CERS6
ceramide synthase 6
chr4_-_48782259 0.18 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr1_-_51796987 0.18 ENST00000262676.5
TTC39A
tetratricopeptide repeat domain 39A
chr5_+_140552218 0.18 ENST00000231137.3
PCDHB7
protocadherin beta 7
chr1_+_15668240 0.18 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr11_+_22696314 0.18 ENST00000532398.1
ENST00000433790.1
GAS2
growth arrest-specific 2
chrX_+_15525426 0.18 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr3_-_151047327 0.18 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr16_+_75182376 0.18 ENST00000570010.1
ENST00000568079.1
ENST00000464850.1
ENST00000332307.4
ENST00000393430.2
ZFP1
ZFP1 zinc finger protein
chr11_-_101000445 0.17 ENST00000534013.1
PGR
progesterone receptor
chr3_-_114790179 0.17 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_+_109204909 0.17 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_-_180707306 0.17 ENST00000479269.1
DNAJC19
DnaJ (Hsp40) homolog, subfamily C, member 19
chr4_-_100356291 0.17 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_+_112939365 0.17 ENST00000272559.4
FBLN7
fibulin 7
chr14_+_23012122 0.17 ENST00000390534.1
TRAJ3
T cell receptor alpha joining 3
chr15_+_54901540 0.17 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr15_+_65843130 0.17 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr19_+_9296279 0.17 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr2_+_132479948 0.16 ENST00000355171.4
C2orf27A
chromosome 2 open reading frame 27A
chr12_+_104337515 0.16 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr12_+_101988627 0.16 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr11_-_59950486 0.16 ENST00000426738.2
ENST00000533023.1
ENST00000420732.2
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr7_-_140482926 0.16 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr4_-_170533723 0.16 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NEK1
NIMA-related kinase 1
chr11_+_44117099 0.16 ENST00000533608.1
EXT2
exostosin glycosyltransferase 2
chr6_+_47749718 0.16 ENST00000489301.2
ENST00000371211.2
ENST00000393699.2
OPN5
opsin 5
chr2_+_108994633 0.16 ENST00000409309.3
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr5_+_140254884 0.16 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr19_+_15852203 0.16 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr4_-_138453606 0.16 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr14_+_35591928 0.16 ENST00000605870.1
ENST00000557404.3
KIAA0391
KIAA0391
chr11_-_124670550 0.16 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr5_-_86534822 0.15 ENST00000445770.2
AC008394.1
Uncharacterized protein
chr15_-_55657428 0.15 ENST00000568543.1
CCPG1
cell cycle progression 1
chr14_-_106926724 0.15 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr2_+_103089756 0.15 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr2_+_89998789 0.15 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr5_-_125930929 0.15 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr10_-_63995871 0.15 ENST00000315289.2
RTKN2
rhotekin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of DBX2_HLX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.5 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.3 1.0 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.3 0.9 GO:0071284 cellular response to lead ion(GO:0071284)
0.3 0.9 GO:0072099 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.3 0.8 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.2 0.7 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 1.5 GO:0097338 response to clozapine(GO:0097338)
0.2 0.6 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 0.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 0.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 0.8 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 0.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 0.6 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.7 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 1.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 1.0 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 1.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.3 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.6 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.4 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 1.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.2 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 1.5 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) cellular lipid biosynthetic process(GO:0097384)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 1.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.6 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0070543 response to linoleic acid(GO:0070543)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.6 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.0 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 1.8 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 1.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.1 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 2.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449) positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.3 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 0.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 1.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.6 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 1.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0000806 Y chromosome(GO:0000806)
0.0 0.1 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 1.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.9 GO:0005605 basal lamina(GO:0005605)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0019770 IgG receptor activity(GO:0019770)
0.3 0.9 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 1.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 1.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 5.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 0.6 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1 0.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 1.2 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.2 GO:1904492 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0022821 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.0 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway