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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for DLX1_HOXA3_BARX2

Z-value: 0.58

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Transcription factors associated with DLX1_HOXA3_BARX2

Gene Symbol Gene ID Gene Info
DLX1
ENSG00000144355.10 distal-less homeobox 1
HOXA3
ENSG00000105997.18 homeobox A3
BARX2
ENSG00000043039.5 BARX homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BARX2hg19_v2_chr11_+_129245796_1292458350.301.4e-01Click!
DLX1hg19_v2_chr2_+_172950227_1729502640.252.2e-01Click!

Activity profile of DLX1_HOXA3_BARX2 motif

Sorted Z-values of DLX1_HOXA3_BARX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_41614909 2.10 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr4_+_41614720 2.07 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr12_-_10022735 1.45 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr3_-_112127981 1.22 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr4_-_186696425 1.14 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr1_+_84609944 1.09 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr14_-_78083112 1.08 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr2_+_191792376 1.07 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr4_-_138453606 0.95 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr7_+_93551011 0.88 ENST00000248564.5
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr14_+_61654271 0.87 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr17_+_67498538 0.86 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr11_-_63376013 0.85 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr17_-_46690839 0.84 ENST00000498634.2
HOXB8
homeobox B8
chr6_+_130339710 0.80 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr3_-_141747950 0.79 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_+_99717230 0.78 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr12_-_10978957 0.77 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr12_-_95510743 0.73 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr19_-_36001113 0.71 ENST00000434389.1
DMKN
dermokine
chr2_-_43266680 0.67 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
AC016735.2
chr2_+_202047596 0.67 ENST00000286186.6
ENST00000360132.3
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr16_-_30122717 0.62 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr14_-_54423529 0.60 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr15_-_20193370 0.60 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr8_-_93115445 0.58 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_201140673 0.58 ENST00000367333.2
TMEM9
transmembrane protein 9
chr5_-_9630463 0.56 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr6_-_109702885 0.56 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr8_-_66474884 0.56 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr13_+_78315295 0.53 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr4_-_25865159 0.52 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr1_+_78470530 0.51 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chrX_-_18690210 0.50 ENST00000379984.3
RS1
retinoschisin 1
chr2_+_90077680 0.50 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr9_+_2159850 0.49 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_+_5135981 0.48 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr8_-_124553437 0.48 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chrX_+_54947229 0.46 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr3_+_111718173 0.46 ENST00000494932.1
TAGLN3
transgelin 3
chr22_-_32860427 0.46 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr1_+_47489240 0.46 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr2_-_183387064 0.45 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr13_+_36050881 0.45 ENST00000537702.1
NBEA
neurobeachin
chr1_-_160924589 0.44 ENST00000368029.3
ITLN2
intelectin 2
chr17_+_48823896 0.44 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr9_+_90112767 0.43 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr2_+_87769459 0.43 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr2_-_89327228 0.42 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr2_-_112237835 0.42 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr6_-_28411241 0.42 ENST00000289788.4
ZSCAN23
zinc finger and SCAN domain containing 23
chr13_+_32313658 0.42 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr3_+_20081515 0.42 ENST00000263754.4
KAT2B
K(lysine) acetyltransferase 2B
chr8_+_98900132 0.41 ENST00000520016.1
MATN2
matrilin 2
chr14_-_45252031 0.41 ENST00000556405.1
RP11-398E10.1
RP11-398E10.1
chr1_+_81771806 0.40 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr4_+_80584903 0.40 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr19_+_50016610 0.39 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr10_+_94594351 0.39 ENST00000371552.4
EXOC6
exocyst complex component 6
chr2_-_183387430 0.39 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_+_12834984 0.38 ENST00000357726.4
PRAMEF12
PRAME family member 12
chr14_-_92413353 0.38 ENST00000556154.1
FBLN5
fibulin 5
chr17_-_5321549 0.38 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr3_-_160823158 0.38 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr3_+_97887544 0.38 ENST00000356526.2
OR5H15
olfactory receptor, family 5, subfamily H, member 15
chr20_-_50418947 0.38 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr12_-_53171128 0.37 ENST00000332411.2
KRT76
keratin 76
chr8_+_70404996 0.37 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr9_+_90112590 0.37 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chr17_-_64187973 0.36 ENST00000583358.1
ENST00000392769.2
CEP112
centrosomal protein 112kDa
chr3_-_123680246 0.36 ENST00000488653.2
CCDC14
coiled-coil domain containing 14
chr19_+_50016411 0.35 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr6_+_155537771 0.35 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr16_+_22501658 0.35 ENST00000415833.2
NPIPB5
nuclear pore complex interacting protein family, member B5
chr3_-_160823040 0.35 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr10_-_93392811 0.35 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr7_-_150020578 0.35 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr20_-_50418972 0.35 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr12_+_20963632 0.35 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr2_+_202047843 0.34 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr9_-_5304432 0.34 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr14_-_23426270 0.34 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4
HAUS augmin-like complex, subunit 4
chr7_+_107224364 0.34 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr14_-_23426337 0.34 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4
HAUS augmin-like complex, subunit 4
chr19_-_44388116 0.33 ENST00000587539.1
ZNF404
zinc finger protein 404
chr14_-_23426322 0.33 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chrX_-_50386648 0.33 ENST00000460112.3
SHROOM4
shroom family member 4
chr18_+_46065393 0.33 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr19_+_17638059 0.33 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr11_+_121447469 0.32 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr9_+_90112741 0.32 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr4_+_144354644 0.32 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr9_+_90112117 0.32 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr12_-_6233828 0.32 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr15_-_55657428 0.32 ENST00000568543.1
CCPG1
cell cycle progression 1
chr13_+_53602894 0.31 ENST00000219022.2
OLFM4
olfactomedin 4
chr10_-_118928543 0.31 ENST00000419373.2
RP11-501J20.2
RP11-501J20.2
chr6_-_32157947 0.31 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr4_-_70725856 0.31 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr6_-_32908765 0.31 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr12_-_96794143 0.31 ENST00000543119.2
CDK17
cyclin-dependent kinase 17
chr15_+_58702742 0.31 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chrX_+_77166172 0.31 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr7_-_150020750 0.30 ENST00000539352.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr3_-_105588231 0.30 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_-_15114658 0.30 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_-_86850949 0.30 ENST00000237455.4
RNF103
ring finger protein 103
chr14_+_22964877 0.30 ENST00000390494.1
TRAJ43
T cell receptor alpha joining 43
chr21_-_32253874 0.30 ENST00000332378.4
KRTAP11-1
keratin associated protein 11-1
chr6_+_89674246 0.29 ENST00000369474.1
AL079342.1
Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr16_+_12059050 0.29 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr12_+_15699286 0.29 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr1_-_68698197 0.29 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr14_-_90085458 0.29 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr1_-_77685084 0.28 ENST00000370812.3
ENST00000359130.1
ENST00000445065.1
ENST00000370813.5
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr10_-_38146510 0.28 ENST00000395867.3
ZNF248
zinc finger protein 248
chr16_+_82090028 0.28 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr20_-_33735070 0.28 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr15_+_35270552 0.28 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr10_+_35484793 0.28 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr12_+_52695617 0.28 ENST00000293525.5
KRT86
keratin 86
chr10_-_7513904 0.27 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr8_+_7783859 0.27 ENST00000400120.3
ZNF705B
zinc finger protein 705B
chr11_+_7618413 0.27 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr20_-_29978286 0.27 ENST00000376315.2
DEFB119
defensin, beta 119
chr22_-_29107919 0.27 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr12_-_23737534 0.27 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr3_-_185538849 0.27 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr10_-_14590644 0.27 ENST00000378470.1
FAM107B
family with sequence similarity 107, member B
chr3_-_105587879 0.26 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chrX_+_86772707 0.25 ENST00000373119.4
KLHL4
kelch-like family member 4
chr2_-_89442621 0.25 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr2_+_87808725 0.25 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr10_+_6779326 0.25 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chrX_+_78200829 0.24 ENST00000544091.1
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chrX_+_78200913 0.24 ENST00000171757.2
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr5_+_1225470 0.24 ENST00000324642.3
ENST00000296821.4
SLC6A18
solute carrier family 6 (neutral amino acid transporter), member 18
chr4_-_138453559 0.24 ENST00000511115.1
PCDH18
protocadherin 18
chr12_-_52995291 0.24 ENST00000293745.2
ENST00000354310.4
KRT72
keratin 72
chr6_-_112575687 0.24 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr19_+_56713670 0.24 ENST00000534327.1
ZSCAN5C
zinc finger and SCAN domain containing 5C
chr11_+_92085262 0.24 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr12_+_20963647 0.24 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr17_-_57229155 0.24 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr2_+_90273679 0.23 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr20_-_56265680 0.23 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr8_+_107738343 0.23 ENST00000521592.1
OXR1
oxidation resistance 1
chr3_-_33686743 0.23 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr12_-_50616382 0.23 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr2_+_103089756 0.23 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr21_+_17442799 0.22 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr7_-_64023410 0.22 ENST00000447137.2
ZNF680
zinc finger protein 680
chr11_-_121986923 0.22 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr1_-_212965104 0.22 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1
NSL1, MIS12 kinetochore complex component
chr13_-_30881134 0.21 ENST00000380617.3
ENST00000441394.1
KATNAL1
katanin p60 subunit A-like 1
chr6_-_38670897 0.21 ENST00000373365.4
GLO1
glyoxalase I
chr12_-_10959892 0.21 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr15_+_49462434 0.20 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
GALK2
galactokinase 2
chr6_+_29079668 0.20 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr3_-_141719195 0.20 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr14_+_31046959 0.20 ENST00000547532.1
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr1_+_54569968 0.20 ENST00000391366.1
AL161915.1
Uncharacterized protein
chr3_+_97868170 0.20 ENST00000437310.1
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr14_-_106552755 0.20 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr7_+_80275953 0.19 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr19_+_2819854 0.19 ENST00000317243.5
ZNF554
zinc finger protein 554
chr6_-_112575838 0.19 ENST00000455073.1
LAMA4
laminin, alpha 4
chr5_-_42812143 0.19 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr11_-_89541743 0.19 ENST00000329758.1
TRIM49
tripartite motif containing 49
chr17_-_39324424 0.19 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr17_-_73663245 0.19 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr3_+_152552685 0.18 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr17_+_48823975 0.18 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr2_-_90538397 0.18 ENST00000443397.3
RP11-685N3.1
Uncharacterized protein
chr20_-_35890211 0.18 ENST00000373614.2
GHRH
growth hormone releasing hormone
chr15_-_37393406 0.18 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr21_+_17909594 0.18 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr7_-_64023441 0.18 ENST00000309683.6
ZNF680
zinc finger protein 680
chr18_-_53303123 0.18 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr12_-_15114603 0.18 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_-_166930131 0.18 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr8_+_62747349 0.18 ENST00000517953.1
ENST00000520097.1
ENST00000519766.1
RP11-705O24.1
RP11-705O24.1
chr7_+_44646162 0.18 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr4_-_109541539 0.17 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr2_-_201729284 0.17 ENST00000434813.2
CLK1
CDC-like kinase 1
chr2_-_201729393 0.17 ENST00000321356.4
CLK1
CDC-like kinase 1
chr17_+_74846230 0.17 ENST00000592919.1
LINC00868
long intergenic non-protein coding RNA 868
chr6_-_112575912 0.17 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr2_+_90211643 0.17 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr6_-_2962331 0.17 ENST00000380524.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr2_+_87565634 0.17 ENST00000421835.2
IGKV3OR2-268
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr12_-_8088871 0.17 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr3_+_98482175 0.17 ENST00000485391.1
ENST00000492254.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr5_+_140625147 0.17 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr2_-_101925055 0.17 ENST00000295317.3
RNF149
ring finger protein 149
chr18_-_44181442 0.17 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr8_-_93978346 0.17 ENST00000523580.1
TRIQK
triple QxxK/R motif containing
chr1_-_185597619 0.16 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
GS1-204I12.1
chr8_-_101571933 0.16 ENST00000520311.1
ANKRD46
ankyrin repeat domain 46
chr17_+_73452545 0.16 ENST00000314256.7
KIAA0195
KIAA0195

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX1_HOXA3_BARX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.3 0.9 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 1.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.6 GO:0055020 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 1.1 GO:0097338 response to clozapine(GO:0097338)
0.1 0.5 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.3 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.7 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.4 GO:0035948 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.3 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.3 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 2.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.3 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.9 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.9 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.7 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.3 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0072615 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.2 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.3 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.4 GO:0000056 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 1.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.4 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.1 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 1.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) meiotic DNA double-strand break formation(GO:0042138) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.5 GO:0009642 response to light intensity(GO:0009642)
0.0 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0061568 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 2.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.0 GO:1904815 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.0 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.0 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.4 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.0 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.0 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.0 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.3 GO:0071751 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.4 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.4 GO:0071953 elastic fiber(GO:0071953)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.8 GO:0005605 basal lamina(GO:0005605)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 1.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2 1.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.2 0.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 0.9 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 1.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 1.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.4 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 1.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.6 GO:0039706 co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 1.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 2.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.0 GO:0004657 proline dehydrogenase activity(GO:0004657)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID FOXO PATHWAY FoxO family signaling
0.0 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation