ISMARA results: DLX4

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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for DLX4_HOXD8

Z-value: 1.14

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Transcription factors associated with DLX4_HOXD8

Gene Symbol	Gene ID	Gene Info
DLX4 Ensembl NCBI GeneCards UniProt	ENSG00000108813.9	distal-less homeobox 4
HOXD8 Ensembl NCBI GeneCards UniProt	ENSG00000175879.7	homeobox D8

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
DLX4	hg19_v2_chr17_+_48046538_48046575	0.06	7.7e-01	Click!
HOXD8	hg19_v2_chr2_+_176994408_176994641	-0.04	8.4e-01	Click!

Activity profile of DLX4_HOXD8 motif

Sorted Z-values of DLX4_HOXD8 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_-_102651343 Show fit	5.57	ENST00000279441.4 ENST00000539681.1	MMP10 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 10 (stromelysin 2)
chr12_+_113344755 Show fit	5.53	ENST00000550883.1	OAS1 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_-_225811747 Show fit	5.36	ENST00000409592.3	DOCK10 Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 10
chr12_+_113354341 Show fit	5.03	ENST00000553152.1	OAS1 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_+_91152303 Show fit	4.28	ENST00000371804.3	IFIT1 Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein with tetratricopeptide repeats 1
chr4_-_76957214 Show fit	3.91	ENST00000306621.3	CXCL11 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-X-C motif) ligand 11
chr11_+_5710919 Show fit	3.17	ENST00000379965.3 ENST00000425490.1	TRIM22 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 22
chr1_+_144989309 Show fit	2.58	ENST00000596396.1	AL590452.1 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr10_-_90712520 Show fit	2.45	ENST00000224784.6	ACTA2 Ensembl NCBI GeneCards UniProt Show fit	actin, alpha 2, smooth muscle, aorta
chr15_-_80263506 Show fit	2.39	ENST00000335661.6	BCL2A1 Ensembl NCBI GeneCards UniProt Show fit	BCL2-related protein A1
chr12_-_52911718 Show fit	2.25	ENST00000548409.1	KRT5 Ensembl NCBI GeneCards UniProt Show fit	keratin 5
chr7_-_115670804 Show fit	2.06	ENST00000320239.7	TFEC Ensembl NCBI GeneCards UniProt Show fit	transcription factor EC
chr7_-_115670792 Show fit	2.06	ENST00000265440.7 ENST00000393485.1	TFEC Ensembl NCBI GeneCards UniProt Show fit	transcription factor EC
chrX_+_144908928 Show fit	2.04	ENST00000408967.2	TMEM257 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 257
chr11_+_35201826 Show fit	1.90	ENST00000531873.1	CD44 Ensembl NCBI GeneCards UniProt Show fit	CD44 molecule (Indian blood group)
chr1_-_33430286 Show fit	1.80	ENST00000373456.7 ENST00000356990.5 ENST00000235150.4	RNF19B Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 19B
chr21_-_15918618 Show fit	1.78	ENST00000400564.1 ENST00000400566.1	SAMSN1 Ensembl NCBI GeneCards UniProt Show fit	SAM domain, SH3 domain and nuclear localization signals 1
chr15_+_94899183 Show fit	1.75	ENST00000557742.1	MCTP2 Ensembl NCBI GeneCards UniProt Show fit	multiple C2 domains, transmembrane 2
chr4_-_76928641 Show fit	1.70	ENST00000264888.5	CXCL9 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-X-C motif) ligand 9
chr12_+_113344811 Show fit	1.59	ENST00000551241.1 ENST00000553185.1 ENST00000550689.1	OAS1 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_-_197115818 Show fit	1.55	ENST00000367409.4 ENST00000294732.7	ASPM Ensembl NCBI GeneCards UniProt Show fit	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr5_-_20575959 Show fit	1.53	ENST00000507958.1	CDH18 Ensembl NCBI GeneCards UniProt Show fit	cadherin 18, type 2
chr14_-_91720224 Show fit	1.48	ENST00000238699.3 ENST00000531499.2	GPR68 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 68
chr3_-_123512688 Show fit	1.45	ENST00000475616.1	MYLK Ensembl NCBI GeneCards UniProt Show fit	myosin light chain kinase
chr21_-_31744557 Show fit	1.45	ENST00000399889.2	KRTAP13-2 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 13-2
chr7_-_47579188 Show fit	1.42	ENST00000398879.1 ENST00000355730.3 ENST00000442536.2 ENST00000458317.2	TNS3 Ensembl NCBI GeneCards UniProt Show fit	tensin 3
chr3_+_122399444 Show fit	1.42	ENST00000474629.2	PARP14 Ensembl NCBI GeneCards UniProt Show fit	poly (ADP-ribose) polymerase family, member 14
chr22_+_23487513 Show fit	1.37	ENST00000263116.2 ENST00000341989.4	RAB36 Ensembl NCBI GeneCards UniProt Show fit	RAB36, member RAS oncogene family
chr1_+_28199047 Show fit	1.35	ENST00000373925.1 ENST00000328928.7 ENST00000373927.3 ENST00000427466.1 ENST00000442118.1 ENST00000373921.3	THEMIS2 Ensembl NCBI GeneCards UniProt Show fit	thymocyte selection associated family member 2
chr5_-_36301984 Show fit	1.34	ENST00000502994.1 ENST00000515759.1 ENST00000296604.3	RANBP3L Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 3-like
chr1_+_79115503 Show fit	1.32	ENST00000370747.4 ENST00000438486.1 ENST00000545124.1	IFI44 Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein 44
chr1_+_196743912 Show fit	1.30	ENST00000367425.4	CFHR3 Ensembl NCBI GeneCards UniProt Show fit	complement factor H-related 3
chr3_-_127441406 Show fit	1.28	ENST00000487473.1 ENST00000484451.1	MGLL Ensembl NCBI GeneCards UniProt Show fit	monoglyceride lipase
chr16_-_28621353 Show fit	1.27	ENST00000567512.1	SULT1A1 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr10_+_90424196 Show fit	1.21	ENST00000394375.3 ENST00000608620.1 ENST00000238983.4 ENST00000355843.2	LIPF Ensembl NCBI GeneCards UniProt Show fit	lipase, gastric
chr4_-_69536346 Show fit	1.18	ENST00000338206.5	UGT2B15 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B15
chr22_+_18632666 Show fit	1.18	ENST00000215794.7	USP18 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 18
chr17_-_64225508 Show fit	1.18	ENST00000205948.6	APOH Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein H (beta-2-glycoprotein I)
chr7_-_139763521 Show fit	1.17	ENST00000263549.3	PARP12 Ensembl NCBI GeneCards UniProt Show fit	poly (ADP-ribose) polymerase family, member 12
chr2_+_103035102 Show fit	1.17	ENST00000264260.2	IL18RAP Ensembl NCBI GeneCards UniProt Show fit	interleukin 18 receptor accessory protein
chr6_-_28411241 Show fit	1.16	ENST00000289788.4	ZSCAN23 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and SCAN domain containing 23
chr4_+_89299994 Show fit	1.16	ENST00000264346.7	HERC6 Ensembl NCBI GeneCards UniProt Show fit	HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr1_-_205091115 Show fit	1.13	ENST00000264515.6 ENST00000367164.1	RBBP5 Ensembl NCBI GeneCards UniProt Show fit	retinoblastoma binding protein 5
chr11_-_102496063 Show fit	1.12	ENST00000260228.2	MMP20 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 20
chr2_-_89513402 Show fit	1.12	ENST00000498435.1	IGKV1-27 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-27
chr16_-_28634874 Show fit	1.11	ENST00000395609.1 ENST00000350842.4	SULT1A1 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_-_70080449 Show fit	1.11	ENST00000446444.1	UGT2B11 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B11
chr5_-_146781153 Show fit	1.10	ENST00000520473.1	DPYSL3 Ensembl NCBI GeneCards UniProt Show fit	dihydropyrimidinase-like 3
chr1_+_87012753 Show fit	1.08	ENST00000370563.3	CLCA4 Ensembl NCBI GeneCards UniProt Show fit	chloride channel accessory 4
chr8_+_104384616 Show fit	1.07	ENST00000520337.1	CTHRC1 Ensembl NCBI GeneCards UniProt Show fit	collagen triple helix repeat containing 1
chr12_+_9822331 Show fit	1.06	ENST00000545918.1 ENST00000543300.1 ENST00000261339.6 ENST00000466035.2	CLEC2D Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 2, member D
chr7_-_92777606 Show fit	1.05	ENST00000437805.1 ENST00000446959.1 ENST00000439952.1 ENST00000414791.1 ENST00000446033.1 ENST00000411955.1 ENST00000318238.4	SAMD9L Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 9-like
chr8_-_90996837 Show fit	1.03	ENST00000519426.1 ENST00000265433.3	NBN Ensembl NCBI GeneCards UniProt Show fit	nibrin
chr21_+_25801041 Show fit	1.01	ENST00000453784.2 ENST00000423581.1	AP000476.1 Ensembl NCBI GeneCards UniProt Show fit	AP000476.1
chr7_-_47621736 Show fit	0.99	ENST00000311160.9	TNS3 Ensembl NCBI GeneCards UniProt Show fit	tensin 3
chr3_+_111717600 Show fit	0.98	ENST00000273368.4	TAGLN3 Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chr11_+_20044096 Show fit	0.97	ENST00000533917.1	NAV2 Ensembl NCBI GeneCards UniProt Show fit	neuron navigator 2
chr6_+_116601265 Show fit	0.97	ENST00000452085.3	DSE Ensembl NCBI GeneCards UniProt Show fit	dermatan sulfate epimerase
chr4_-_169239921 Show fit	0.96	ENST00000514995.1 ENST00000393743.3	DDX60 Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr5_-_135290705 Show fit	0.95	ENST00000274507.1	LECT2 Ensembl NCBI GeneCards UniProt Show fit	leukocyte cell-derived chemotaxin 2
chr8_+_104310661 Show fit	0.92	ENST00000522566.1	FZD6 Ensembl NCBI GeneCards UniProt Show fit	frizzled family receptor 6
chr3_-_12587055 Show fit	0.91	ENST00000564146.3	C3orf83 Ensembl NCBI GeneCards UniProt Show fit	chromosome 3 open reading frame 83
chr4_+_70916119 Show fit	0.91	ENST00000246896.3 ENST00000511674.1	HTN1 Ensembl NCBI GeneCards UniProt Show fit	histatin 1
chr3_-_79816965 Show fit	0.90	ENST00000464233.1	ROBO1 Ensembl NCBI GeneCards UniProt Show fit	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr20_-_35580240 Show fit	0.89	ENST00000262878.4	SAMHD1 Ensembl NCBI GeneCards UniProt Show fit	SAM domain and HD domain 1
chr22_+_21128167 Show fit	0.89	ENST00000215727.5	SERPIND1 Ensembl NCBI GeneCards UniProt Show fit	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr11_+_124055923 Show fit	0.88	ENST00000318666.6	OR10D3 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor, family 10, subfamily D, member 3 (non-functional)
chr1_-_89591749 Show fit	0.87	ENST00000370466.3	GBP2 Ensembl NCBI GeneCards UniProt Show fit	guanylate binding protein 2, interferon-inducible
chr18_+_21693306 Show fit	0.87	ENST00000540918.2	TTC39C Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 39C
chr11_-_117748138 Show fit	0.87	ENST00000527717.1	FXYD6 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 6
chr1_+_169079823 Show fit	0.87	ENST00000367813.3	ATP1B1 Ensembl NCBI GeneCards UniProt Show fit	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_+_156696362 Show fit	0.87	ENST00000377576.3	CYFIP2 Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic FMR1 interacting protein 2
chr12_+_21590549 Show fit	0.86	ENST00000545178.1 ENST00000240651.9	PYROXD1 Ensembl NCBI GeneCards UniProt Show fit	pyridine nucleotide-disulphide oxidoreductase domain 1
chr3_-_156272924 Show fit	0.86	ENST00000467789.1 ENST00000265044.2	SSR3 Ensembl NCBI GeneCards UniProt Show fit	signal sequence receptor, gamma (translocon-associated protein gamma)
chrX_+_30261847 Show fit	0.86	ENST00000378981.3 ENST00000397550.1	MAGEB1 Ensembl NCBI GeneCards UniProt Show fit	melanoma antigen family B, 1
chr11_-_117747434 Show fit	0.85	ENST00000529335.2 ENST00000530956.1 ENST00000260282.4	FXYD6 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 6
chr5_+_42756903 Show fit	0.85	ENST00000361970.5 ENST00000388827.4	CCDC152 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 152
chr15_+_69857515 Show fit	0.85	ENST00000559477.1	RP11-279F6.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-279F6.1
chr8_+_27632083 Show fit	0.83	ENST00000519637.1	ESCO2 Ensembl NCBI GeneCards UniProt Show fit	establishment of sister chromatid cohesion N-acetyltransferase 2
chr11_+_55578854 Show fit	0.83	ENST00000333973.2	OR5L1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor, family 5, subfamily L, member 1
chr8_-_13134045 Show fit	0.82	ENST00000512044.2	DLC1 Ensembl NCBI GeneCards UniProt Show fit	deleted in liver cancer 1
chr19_-_47291843 Show fit	0.82	ENST00000542575.2	SLC1A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 (neutral amino acid transporter), member 5
chr17_-_39306054 Show fit	0.81	ENST00000343246.4	KRTAP4-5 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 4-5
chr3_-_191000172 Show fit	0.81	ENST00000427544.2	UTS2B Ensembl NCBI GeneCards UniProt Show fit	urotensin 2B
chr19_+_54466179 Show fit	0.80	ENST00000270458.2	CACNG8 Ensembl NCBI GeneCards UniProt Show fit	calcium channel, voltage-dependent, gamma subunit 8
chr11_+_19798964 Show fit	0.79	ENST00000527559.2	NAV2 Ensembl NCBI GeneCards UniProt Show fit	neuron navigator 2
chr12_-_43833515 Show fit	0.78	ENST00000549670.1 ENST00000395541.2	ADAMTS20 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr11_-_57335750 Show fit	0.78	ENST00000340573.4	UBE2L6 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-conjugating enzyme E2L 6
chr4_-_70826725 Show fit	0.78	ENST00000353151.3	CSN2 Ensembl NCBI GeneCards UniProt Show fit	casein beta
chr6_+_153552455 Show fit	0.77	ENST00000392385.2	AL590867.1 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr3_-_146213722 Show fit	0.76	ENST00000336685.2 ENST00000489015.1	PLSCR2 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 2
chr1_-_27998689 Show fit	0.76	ENST00000339145.4 ENST00000362020.4 ENST00000361157.6	IFI6 Ensembl NCBI GeneCards UniProt Show fit	interferon, alpha-inducible protein 6
chr12_-_71182695 Show fit	0.75	ENST00000342084.4	PTPRR Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, receptor type, R
chr12_+_9822293 Show fit	0.75	ENST00000261340.7 ENST00000290855.6	CLEC2D Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 2, member D
chr12_+_115800817 Show fit	0.74	ENST00000547948.1	RP11-116D17.1 Ensembl NCBI GeneCards UniProt Show fit	HCG2038717; Uncharacterized protein
chr5_+_156712372 Show fit	0.74	ENST00000541131.1	CYFIP2 Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic FMR1 interacting protein 2
chr18_-_33702078 Show fit	0.73	ENST00000586829.1	SLC39A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 (zinc transporter), member 6
chr11_+_18433840 Show fit	0.72	ENST00000541669.1 ENST00000280704.4	LDHC Ensembl NCBI GeneCards UniProt Show fit	lactate dehydrogenase C
chr2_+_185463093 Show fit	0.72	ENST00000302277.6	ZNF804A Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 804A
chr2_+_152214098 Show fit	0.71	ENST00000243347.3	TNFAIP6 Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor, alpha-induced protein 6
chr10_-_79398250 Show fit	0.70	ENST00000286627.5	KCNMA1 Ensembl NCBI GeneCards UniProt Show fit	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_-_87804815 Show fit	0.70	ENST00000369582.2	CGA Ensembl NCBI GeneCards UniProt Show fit	glycoprotein hormones, alpha polypeptide
chr13_-_47471155 Show fit	0.70	ENST00000543956.1 ENST00000542664.1	HTR2A Ensembl NCBI GeneCards UniProt Show fit	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr10_+_57358750 Show fit	0.69	ENST00000512524.2	MTRNR2L5 Ensembl NCBI GeneCards UniProt Show fit	MT-RNR2-like 5
chr11_-_117747607 Show fit	0.69	ENST00000540359.1 ENST00000539526.1	FXYD6 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 6
chr3_-_194188956 Show fit	0.69	ENST00000256031.4 ENST00000446356.1	ATP13A3 Ensembl NCBI GeneCards UniProt Show fit	ATPase type 13A3
chr1_+_167599330 Show fit	0.68	ENST00000367854.3 ENST00000361496.3	RCSD1 Ensembl NCBI GeneCards UniProt Show fit	RCSD domain containing 1
chr8_-_62559366 Show fit	0.68	ENST00000522919.1	ASPH Ensembl NCBI GeneCards UniProt Show fit	aspartate beta-hydroxylase
chr1_+_74701062 Show fit	0.68	ENST00000326637.3	TNNI3K Ensembl NCBI GeneCards UniProt Show fit	TNNI3 interacting kinase
chr10_+_60028818 Show fit	0.67	ENST00000333926.5	CISD1 Ensembl NCBI GeneCards UniProt Show fit	CDGSH iron sulfur domain 1
chr7_+_142031986 Show fit	0.67	ENST00000547918.2	TRBV7-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 7-1 (non-functional)
chr9_-_85882145 Show fit	0.67	ENST00000328788.1	FRMD3 Ensembl NCBI GeneCards UniProt Show fit	FERM domain containing 3
chr11_-_5173599 Show fit	0.67	ENST00000328942.1	OR52A1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor, family 52, subfamily A, member 1
chr20_+_31805131 Show fit	0.67	ENST00000375454.3 ENST00000375452.3	BPIFA3 Ensembl NCBI GeneCards UniProt Show fit	BPI fold containing family A, member 3
chr5_-_93077293 Show fit	0.67	ENST00000510627.4	POU5F2 Ensembl NCBI GeneCards UniProt Show fit	POU domain class 5, transcription factor 2
chr8_+_27631903 Show fit	0.67	ENST00000305188.8	ESCO2 Ensembl NCBI GeneCards UniProt Show fit	establishment of sister chromatid cohesion N-acetyltransferase 2
chr18_-_19994830 Show fit	0.67	ENST00000525417.1	CTAGE1 Ensembl NCBI GeneCards UniProt Show fit	cutaneous T-cell lymphoma-associated antigen 1
chr10_-_4285923 Show fit	0.66	ENST00000418372.1 ENST00000608792.1	LINC00702 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 702
chr8_+_11961898 Show fit	0.66	ENST00000400085.3	ZNF705D Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 705D
chr4_+_123653807 Show fit	0.66	ENST00000314218.3 ENST00000542236.1	BBS12 Ensembl NCBI GeneCards UniProt Show fit	Bardet-Biedl syndrome 12
chr4_+_96012614 Show fit	0.66	ENST00000264568.4	BMPR1B Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein receptor, type IB
chr1_+_205197304 Show fit	0.64	ENST00000358024.3	TMCC2 Ensembl NCBI GeneCards UniProt Show fit	transmembrane and coiled-coil domain family 2
chr15_+_71389281 Show fit	0.64	ENST00000355327.3	THSD4 Ensembl NCBI GeneCards UniProt Show fit	thrombospondin, type I, domain containing 4
chr3_+_111717511 Show fit	0.64	ENST00000478951.1 ENST00000393917.2	TAGLN3 Ensembl NCBI GeneCards UniProt Show fit	transgelin 3
chr7_-_115608304 Show fit	0.64	ENST00000457268.1	TFEC Ensembl NCBI GeneCards UniProt Show fit	transcription factor EC
chr5_+_75378997 Show fit	0.63	ENST00000502798.2	SV2C Ensembl NCBI GeneCards UniProt Show fit	synaptic vesicle glycoprotein 2C
chr11_-_7847519 Show fit	0.63	ENST00000328375.1	OR5P3 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor, family 5, subfamily P, member 3
chr15_+_90895471 Show fit	0.63	ENST00000354377.3 ENST00000379090.5	ZNF774 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 774
chr5_+_129083772 Show fit	0.63	ENST00000564719.1	KIAA1024L Ensembl NCBI GeneCards UniProt Show fit	KIAA1024-like
chr5_-_160279207 Show fit	0.62	ENST00000327245.5	ATP10B Ensembl NCBI GeneCards UniProt Show fit	ATPase, class V, type 10B
chr19_+_45449301 Show fit	0.62	ENST00000591597.1	APOC2 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein C-II
chr12_+_69202975 Show fit	0.61	ENST00000544561.1 ENST00000393410.1 ENST00000299252.4 ENST00000360430.2 ENST00000517852.1 ENST00000545204.1 ENST00000393413.3 ENST00000350057.5 ENST00000348801.2 ENST00000478070.1	MDM2 Ensembl NCBI GeneCards UniProt Show fit	MDM2 oncogene, E3 ubiquitin protein ligase
chr1_-_89531041 Show fit	0.60	ENST00000370473.4	GBP1 Ensembl NCBI GeneCards UniProt Show fit	guanylate binding protein 1, interferon-inducible
chr12_-_89919765 Show fit	0.60	ENST00000541909.1 ENST00000313546.3	POC1B Ensembl NCBI GeneCards UniProt Show fit	POC1 centriolar protein B
chr17_-_64216748 Show fit	0.60	ENST00000585162.1	APOH Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein H (beta-2-glycoprotein I)
chr4_-_79860506 Show fit	0.60	ENST00000295462.3 ENST00000380645.4 ENST00000512733.1	PAQR3 Ensembl NCBI GeneCards UniProt Show fit	progestin and adipoQ receptor family member III
chr3_+_108855558 Show fit	0.59	ENST00000467240.1 ENST00000477643.1 ENST00000479039.1 ENST00000593799.1	RP11-59E19.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-59E19.1
chr5_-_59481406 Show fit	0.59	ENST00000546160.1	PDE4D Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D, cAMP-specific
chr6_+_89674246 Show fit	0.59	ENST00000369474.1	AL079342.1 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr8_-_90996459 Show fit	0.59	ENST00000517337.1 ENST00000409330.1	NBN Ensembl NCBI GeneCards UniProt Show fit	nibrin
chr10_-_14050522 Show fit	0.59	ENST00000342409.2	FRMD4A Ensembl NCBI GeneCards UniProt Show fit	FERM domain containing 4A
chr4_+_74301880 Show fit	0.59	ENST00000395792.2 ENST00000226359.2	AFP Ensembl NCBI GeneCards UniProt Show fit	alpha-fetoprotein
chr1_+_120254510 Show fit	0.59	ENST00000369409.4	PHGDH Ensembl NCBI GeneCards UniProt Show fit	phosphoglycerate dehydrogenase
chr11_+_35198243 Show fit	0.59	ENST00000528455.1	CD44 Ensembl NCBI GeneCards UniProt Show fit	CD44 molecule (Indian blood group)
chr6_-_3195981 Show fit	0.58	ENST00000425384.2 ENST00000435043.2	RP1-40E16.9 Ensembl NCBI GeneCards UniProt Show fit	RP1-40E16.9
chr1_+_196743943 Show fit	0.58	ENST00000471440.2 ENST00000391985.3	CFHR3 Ensembl NCBI GeneCards UniProt Show fit	complement factor H-related 3
chr12_-_122985067 Show fit	0.58	ENST00000540586.1 ENST00000543897.1	ZCCHC8 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, CCHC domain containing 8
chr12_-_11062161 Show fit	0.58	ENST00000390677.2	TAS2R13 Ensembl NCBI GeneCards UniProt Show fit	taste receptor, type 2, member 13
chr17_+_34640031 Show fit	0.57	ENST00000339270.6 ENST00000482104.1	CCL4L2 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 4-like 2
chr1_-_72566613 Show fit	0.57	ENST00000306821.3	NEGR1 Ensembl NCBI GeneCards UniProt Show fit	neuronal growth regulator 1
chr1_+_86934526 Show fit	0.57	ENST00000394711.1	CLCA1 Ensembl NCBI GeneCards UniProt Show fit	chloride channel accessory 1
chr10_+_118305435 Show fit	0.57	ENST00000369221.2	PNLIP Ensembl NCBI GeneCards UniProt Show fit	pancreatic lipase
chr1_+_158978768 Show fit	0.57	ENST00000447473.2	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon, gamma-inducible protein 16
chr3_-_112565703 Show fit	0.57	ENST00000488794.1	CD200R1L Ensembl NCBI GeneCards UniProt Show fit	CD200 receptor 1-like
chr12_-_102224457 Show fit	0.57	ENST00000549165.1 ENST00000549940.1 ENST00000392919.4	GNPTAB Ensembl NCBI GeneCards UniProt Show fit	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr12_-_22094336 Show fit	0.57	ENST00000326684.4	ABCC9 Ensembl NCBI GeneCards UniProt Show fit	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_-_39979576 Show fit	0.56	ENST00000303538.8 ENST00000503396.1	PDS5A Ensembl NCBI GeneCards UniProt Show fit	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr12_+_26348429 Show fit	0.56	ENST00000242729.2	SSPN Ensembl NCBI GeneCards UniProt Show fit	sarcospan
chr3_+_94657086 Show fit	0.56	ENST00000463200.1	LINC00879 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 879
chr5_+_121465207 Show fit	0.56	ENST00000296600.4	ZNF474 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 474
chr17_-_39324424 Show fit	0.55	ENST00000391356.2	KRTAP4-3 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 4-3
chr14_+_52164820 Show fit	0.55	ENST00000554167.1	FRMD6 Ensembl NCBI GeneCards UniProt Show fit	FERM domain containing 6
chr4_-_70518941 Show fit	0.55	ENST00000286604.4 ENST00000505512.1 ENST00000514019.1	UGT2A1 Ensembl NCBI GeneCards UniProt Show fit UGT2A1 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr11_+_12308447 Show fit	0.55	ENST00000256186.2	MICALCL Ensembl NCBI GeneCards UniProt Show fit	MICAL C-terminal like
chr18_+_76829441 Show fit	0.54	ENST00000458297.2	ATP9B Ensembl NCBI GeneCards UniProt Show fit	ATPase, class II, type 9B
chr1_-_89357179 Show fit	0.54	ENST00000448623.1 ENST00000418217.1 ENST00000370500.5	GTF2B Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIB
chr14_-_21566731 Show fit	0.54	ENST00000360947.3	ZNF219 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 219
chr16_-_28621312 Show fit	0.54	ENST00000314752.7	SULT1A1 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr8_+_92082424 Show fit	0.54	ENST00000285420.4 ENST00000404789.3	OTUD6B Ensembl NCBI GeneCards UniProt Show fit	OTU domain containing 6B
chrX_+_84258832 Show fit	0.54	ENST00000373173.2	APOOL Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein O-like
chr21_-_32185570 Show fit	0.54	ENST00000329621.4	KRTAP8-1 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 8-1
chr10_-_61900762 Show fit	0.54	ENST00000355288.2	ANK3 Ensembl NCBI GeneCards UniProt Show fit	ankyrin 3, node of Ranvier (ankyrin G)
chr7_+_99195677 Show fit	0.54	ENST00000431679.1	GS1-259H13.2 Ensembl NCBI GeneCards UniProt Show fit	GS1-259H13.2
chr11_-_5345582 Show fit	0.53	ENST00000328813.2	OR51B2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor, family 51, subfamily B, member 2
chr1_-_36906474 Show fit	0.53	ENST00000433045.2	OSCP1 Ensembl NCBI GeneCards UniProt Show fit	organic solute carrier partner 1
chr17_+_41132564 Show fit	0.53	ENST00000361677.1 ENST00000589705.1	RUNDC1 Ensembl NCBI GeneCards UniProt Show fit	RUN domain containing 1
chr4_-_159956333 Show fit	0.53	ENST00000434826.2	C4orf45 Ensembl NCBI GeneCards UniProt Show fit	chromosome 4 open reading frame 45
chr12_+_26348246 Show fit	0.52	ENST00000422622.2	SSPN Ensembl NCBI GeneCards UniProt Show fit	sarcospan
chr18_-_70211691 Show fit	0.52	ENST00000269503.4	CBLN2 Ensembl NCBI GeneCards UniProt Show fit	cerebellin 2 precursor
chr11_-_57335280 Show fit	0.52	ENST00000287156.4	UBE2L6 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-conjugating enzyme E2L 6
chr1_-_247921982 Show fit	0.52	ENST00000408896.2	OR1C1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor, family 1, subfamily C, member 1
chrM_-_14670 Show fit	0.52	ENST00000361681.2	MT-ND6 Ensembl NCBI GeneCards UniProt Show fit	mitochondrially encoded NADH dehydrogenase 6
chr22_-_36556821 Show fit	0.52	ENST00000531095.1 ENST00000397293.2 ENST00000349314.2	APOL3 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein L, 3
chr4_+_70894130 Show fit	0.52	ENST00000526767.1 ENST00000530128.1 ENST00000381057.3	HTN3 Ensembl NCBI GeneCards UniProt Show fit	histatin 3
chr1_-_60539422 Show fit	0.52	ENST00000371201.3	C1orf87 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 87
chr11_-_104972158 Show fit	0.52	ENST00000598974.1 ENST00000593315.1 ENST00000594519.1 ENST00000415981.2 ENST00000525374.1 ENST00000375707.1	CASP1 Ensembl NCBI GeneCards UniProt Show fit CARD16 Ensembl NCBI GeneCards UniProt Show fit CARD17 Ensembl NCBI GeneCards UniProt Show fit	caspase 1, apoptosis-related cysteine peptidase caspase recruitment domain family, member 16 caspase recruitment domain family, member 17
chr4_-_120243545 Show fit	0.51	ENST00000274024.3	FABP2 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 2, intestinal
chr1_+_225600404 Show fit	0.51	ENST00000366845.2	AC092811.1 Ensembl NCBI GeneCards UniProt Show fit	AC092811.1
chr10_-_115614127 Show fit	0.51	ENST00000369305.1	DCLRE1A Ensembl NCBI GeneCards UniProt Show fit	DNA cross-link repair 1A
chr2_-_69098566 Show fit	0.51	ENST00000295379.1	BMP10 Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein 10
chr17_-_39254391 Show fit	0.50	ENST00000333822.4	KRTAP4-8 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 4-8
chr6_+_116782527 Show fit	0.50	ENST00000368606.3 ENST00000368605.1	FAM26F Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 26, member F
chr16_-_28621298 Show fit	0.50	ENST00000566189.1	SULT1A1 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_-_119759795 Show fit	0.49	ENST00000419654.2	SEC24D Ensembl NCBI GeneCards UniProt Show fit	SEC24 family member D
chr17_-_4090402 Show fit	0.49	ENST00000574736.1	ANKFY1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and FYVE domain containing 1
chr7_-_149158187 Show fit	0.49	ENST00000247930.4	ZNF777 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 777
chr11_-_111649015 Show fit	0.49	ENST00000529841.1	RP11-108O10.2 Ensembl NCBI GeneCards UniProt Show fit	RP11-108O10.2
chr6_+_26402465 Show fit	0.49	ENST00000476549.2 ENST00000289361.6 ENST00000450085.2 ENST00000425234.2 ENST00000427334.1 ENST00000506698.1	BTN3A1 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin, subfamily 3, member A1
chr1_-_183622442 Show fit	0.49	ENST00000308641.4	APOBEC4 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr12_+_14572070 Show fit	0.48	ENST00000545769.1 ENST00000428217.2 ENST00000396279.2 ENST00000542514.1 ENST00000536279.1	ATF7IP Ensembl NCBI GeneCards UniProt Show fit	activating transcription factor 7 interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX4_HOXD8

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.3	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.6	5.6	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.5	1.6	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.4	1.8	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.4	2.5	GO:0090131	mesenchyme migration(GO:0090131)
0.4	5.4	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.4	1.1	GO:0070173	regulation of enamel mineralization(GO:0070173)
0.3	2.5	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3	0.9	GO:0021836	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.3	0.9	GO:0016256	N-glycan processing to lysosome(GO:0016256)
0.3	1.6	GO:0034421	post-translational protein acetylation(GO:0034421)
0.3	0.8	GO:0071301	cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.3	0.8	GO:1903487	regulation of lactation(GO:1903487)
0.2	1.0	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2	0.9	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.2	0.9	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2	3.0	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.2	0.5	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.2	1.8	GO:0021564	vagus nerve development(GO:0021564)
0.2	0.8	GO:0036229	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2	0.6	GO:0006566	threonine metabolic process(GO:0006566)
0.2	1.6	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.2	0.7	GO:0072660	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2	1.3	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.2	0.9	GO:0006203	dGTP catabolic process(GO:0006203)
0.2	0.9	GO:1903281	positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.2	1.3	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.2	1.2	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2	1.5	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2	0.5	GO:0043686	co-translational protein modification(GO:0043686)
0.2	0.6	GO:0060697	positive regulation of phospholipid catabolic process(GO:0060697)
0.2	0.6	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2	0.5	GO:0099545	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.2	1.1	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.1	1.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	13.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	0.7	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1	0.7	GO:0048165	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1	0.4	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.5	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.1	0.4	GO:0045643	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1	0.5	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.1	0.4	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1	0.4	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1	0.6	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.7	GO:0019249	lactate biosynthetic process(GO:0019249)
0.1	0.4	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	1.4	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	0.7	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1	0.2	GO:0071373	cellular response to luteinizing hormone stimulus(GO:0071373)
0.1	0.1	GO:0072053	renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.1	0.3	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.1	0.8	GO:0003383	apical constriction(GO:0003383)
0.1	0.5	GO:0060356	leucine import(GO:0060356)
0.1	0.4	GO:0009726	detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.1	0.2	GO:2000466	negative regulation of glycogen (starch) synthase activity(GO:2000466)
0.1	0.5	GO:2000639	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1	0.4	GO:0009236	cobalamin biosynthetic process(GO:0009236)
0.1	0.6	GO:1904823	pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1	0.3	GO:0042495	detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1	0.4	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1	1.3	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.8	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.1	0.5	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.1	0.2	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.1	0.4	GO:0001970	positive regulation of activation of membrane attack complex(GO:0001970)
0.1	0.3	GO:0002636	positive regulation of germinal center formation(GO:0002636)
0.1	0.5	GO:1904798	positive regulation of core promoter binding(GO:1904798)
0.1	0.4	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1	0.3	GO:1902031	regulation of pentose-phosphate shunt(GO:0043456) regulation of NADP metabolic process(GO:1902031)
0.1	0.8	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	2.6	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	0.4	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.1	0.3	GO:0061713	neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.1	0.3	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1	0.2	GO:0009107	lipoate biosynthetic process(GO:0009107)
0.1	0.4	GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1	1.7	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	0.7	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.1	0.5	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.3	GO:0046110	xanthine metabolic process(GO:0046110)
0.1	2.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1	0.4	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1	0.3	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.1	0.3	GO:0071934	thiamine transmembrane transport(GO:0071934)
0.1	0.8	GO:0034465	response to carbon monoxide(GO:0034465)
0.1	0.3	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.2	GO:0006742	NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1	0.4	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	0.3	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.1	GO:1903422	negative regulation of synaptic vesicle recycling(GO:1903422)
0.1	0.4	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.1	0.8	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.1	0.9	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.1	5.9	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.3	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1	0.4	GO:0010615	positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1	0.8	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.1	0.7	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1	0.3	GO:0032053	ciliary basal body organization(GO:0032053)
0.1	0.6	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	0.5	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.2	GO:1902567	immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.1	0.4	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	0.4	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.1	0.3	GO:0048749	compound eye development(GO:0048749)
0.1	0.4	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1	0.3	GO:0030035	microspike assembly(GO:0030035)
0.1	0.2	GO:1904565	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1	0.1	GO:1902573	positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1	0.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1	0.5	GO:0070166	enamel mineralization(GO:0070166)
0.1	0.3	GO:0035617	stress granule disassembly(GO:0035617)
0.1	0.2	GO:0005986	sucrose biosynthetic process(GO:0005986)
0.1	0.3	GO:0015692	lead ion transport(GO:0015692)
0.1	0.8	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.4	GO:0080009	mRNA methylation(GO:0080009)
0.1	2.6	GO:0008210	estrogen metabolic process(GO:0008210)
0.1	0.5	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.2	GO:0000103	sulfate assimilation(GO:0000103)
0.1	0.4	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.1	0.2	GO:0044278	cell wall disruption in other organism(GO:0044278)
0.1	0.2	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1	0.3	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.1	0.3	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1	0.2	GO:0035915	pore formation in membrane of other organism(GO:0035915)
0.1	0.3	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.1	0.2	GO:0070898	RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.1	0.2	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.1	0.2	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.1	0.9	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.4	GO:0050893	sensory processing(GO:0050893)
0.0	1.1	GO:0072643	interferon-gamma secretion(GO:0072643)
0.0	0.1	GO:0031448	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0	0.1	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0	0.3	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.2	GO:0060133	somatotropin secreting cell development(GO:0060133)
0.0	0.0	GO:1902227	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0	0.4	GO:1904386	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0	0.1	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.0	0.5	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
0.0	1.1	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.4	GO:0035973	aggrephagy(GO:0035973)
0.0	0.2	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.0	0.4	GO:1902570	protein localization to nucleolus(GO:1902570)
0.0	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.3	GO:0032202	telomere assembly(GO:0032202)
0.0	0.3	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.0	GO:0014839	myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0	0.2	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	1.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0	0.1	GO:0046495	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.0	0.6	GO:0052695	cellular glucuronidation(GO:0052695)
0.0	1.6	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.1	GO:0010650	positive regulation of cell communication by electrical coupling(GO:0010650)
0.0	0.3	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.4	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.4	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.3	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:1900365	positive regulation of mRNA polyadenylation(GO:1900365)
0.0	0.2	GO:0070970	interleukin-2 secretion(GO:0070970)
0.0	0.1	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0	0.1	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0	0.1	GO:0051758	homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0	0.1	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.0	0.1	GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0	0.4	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.7	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	2.6	GO:0070206	protein trimerization(GO:0070206)
0.0	0.2	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0	0.5	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0	0.6	GO:0071474	cellular hyperosmotic response(GO:0071474)
0.0	0.3	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.1	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.2	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.0	0.5	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.1	GO:0002101	tRNA wobble cytosine modification(GO:0002101) oxidative single-stranded DNA demethylation(GO:0035552)
0.0	0.2	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.0	0.2	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0	0.9	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.2	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.5	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.0	0.4	GO:0086069	bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0	0.1	GO:0002740	negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0	0.1	GO:0034334	adherens junction maintenance(GO:0034334)
0.0	0.1	GO:0005988	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.3	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.2	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.3	GO:0006069	ethanol oxidation(GO:0006069)
0.0	0.3	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	3.7	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	7.1	GO:0031424	keratinization(GO:0031424)
0.0	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.2	GO:0031392	regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0	0.2	GO:0042262	DNA protection(GO:0042262)
0.0	0.1	GO:1904020	regulation of G-protein coupled receptor internalization(GO:1904020)
0.0	0.2	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.0	0.3	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.3	GO:0032264	IMP salvage(GO:0032264)
0.0	0.2	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0	0.1	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
0.0	0.5	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.3	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.0	0.3	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.2	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.1	GO:0051037	regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0	0.2	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.0	1.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696) negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0	2.4	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.0	0.3	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.0	0.1	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.0	0.5	GO:0061365	positive regulation of triglyceride lipase activity(GO:0061365)
0.0	0.4	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.1	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0	0.4	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.2	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.0	0.1	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
0.0	0.2	GO:0033504	floor plate development(GO:0033504)
0.0	1.5	GO:0002820	negative regulation of adaptive immune response(GO:0002820)
0.0	0.5	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.3	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.0	0.4	GO:0019532	oxalate transport(GO:0019532)
0.0	0.3	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.1	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0	0.1	GO:0015827	tryptophan transport(GO:0015827)
0.0	0.1	GO:0032218	riboflavin transport(GO:0032218)
0.0	4.7	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.0	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0	0.2	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.3	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.2	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.1	GO:0001694	histamine biosynthetic process(GO:0001694)
0.0	0.1	GO:0003218	His-Purkinje system development(GO:0003164) bundle of His development(GO:0003166) cardiac left ventricle formation(GO:0003218)
0.0	0.0	GO:0009441	glycolate metabolic process(GO:0009441)
0.0	0.6	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	1.0	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	1.1	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	0.2	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.2	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0001507	acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0	0.4	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.1	GO:0031291	Ran protein signal transduction(GO:0031291)
0.0	0.2	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.2	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.5	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.2	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	0.2	GO:0072025	distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0	0.6	GO:0060039	pericardium development(GO:0060039)
0.0	0.5	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.7	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.7	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.8	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.4	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.1	GO:0015744	tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) succinate transmembrane transport(GO:0071422)
0.0	0.2	GO:0000066	mitochondrial ornithine transport(GO:0000066)
0.0	0.4	GO:0006265	DNA topological change(GO:0006265)
0.0	0.1	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.2	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.2	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:0002765	immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0	0.1	GO:0014062	regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.4	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.4	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.0	1.1	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.3	GO:0070933	histone H4 deacetylation(GO:0070933)
0.0	1.0	GO:0036260	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.0	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0	0.1	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0	0.4	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.2	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.3	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0019521	aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0	0.2	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.0	0.2	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.3	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	0.2	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	0.0	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.0	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.5	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0097052	L-kynurenine metabolic process(GO:0097052)
0.0	0.1	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0	0.5	GO:0030728	ovulation(GO:0030728)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.3	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0036371	protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0	0.4	GO:0045974	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.1	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.9	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.2	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.4	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.9	GO:1901998	toxin transport(GO:1901998)
0.0	0.3	GO:0071539	protein localization to centrosome(GO:0071539)
0.0	0.1	GO:0097461	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0	0.1	GO:1902074	response to salt(GO:1902074)
0.0	0.0	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.4	GO:0006363	transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0	0.0	GO:0090238	positive regulation of arachidonic acid secretion(GO:0090238)
0.0	0.1	GO:0097186	amelogenesis(GO:0097186)
0.0	0.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	1.9	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0	0.0	GO:0002522	leukocyte migration involved in immune response(GO:0002522)
0.0	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742) positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	1.3	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.2	GO:0045060	negative thymic T cell selection(GO:0045060)
0.0	0.3	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.1	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.1	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0	0.2	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.1	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.0	0.1	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	1.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.1	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
0.0	0.2	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.0	0.1	GO:0072679	thymocyte migration(GO:0072679)
0.0	0.1	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.0	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.1	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.1	GO:0006705	mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0	0.6	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.4	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.6	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.7	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	1.4	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.4	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.0	0.0	GO:0061341	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0	0.2	GO:0051194	positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0	0.1	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.4	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0	0.8	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.4	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.1	GO:0071386	cellular response to corticosterone stimulus(GO:0071386)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0035799	ureter maturation(GO:0035799)
0.0	0.4	GO:0033014	porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0	0.4	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.0	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.4	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.2	GO:0051642	centrosome localization(GO:0051642)
0.0	0.0	GO:0002232	leukocyte chemotaxis involved in inflammatory response(GO:0002232) respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) positive regulation of respiratory burst involved in inflammatory response(GO:0060265)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.4	2.5	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2	1.8	GO:0044194	cytolytic granule(GO:0044194)
0.2	1.8	GO:0030870	Mre11 complex(GO:0030870)
0.2	0.9	GO:0005726	perichromatin fibrils(GO:0005726)
0.2	1.5	GO:0036449	microtubule minus-end(GO:0036449)
0.2	0.9	GO:0097179	NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.1	1.8	GO:0031089	platelet dense granule lumen(GO:0031089)
0.1	0.3	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1	1.6	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	0.9	GO:0070852	cell body fiber(GO:0070852)
0.1	0.5	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.1	1.1	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	0.4	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.1	1.8	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.6	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.4	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.1	0.6	GO:0061617	MICOS complex(GO:0061617)
0.1	0.3	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1	0.4	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.5	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.1	0.2	GO:0031021	interphase microtubule organizing center(GO:0031021)
0.1	0.5	GO:0030061	mitochondrial crista(GO:0030061)
0.1	5.6	GO:0045095	keratin filament(GO:0045095)
0.1	0.5	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	0.6	GO:0005579	membrane attack complex(GO:0005579)
0.1	0.2	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.1	0.2	GO:1990423	RZZ complex(GO:1990423)
0.1	0.4	GO:0090661	box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1	1.4	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.2	GO:0034686	integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.1	0.3	GO:0070826	paraferritin complex(GO:0070826)
0.1	0.2	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1	0.4	GO:0032437	cuticular plate(GO:0032437)
0.1	1.0	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.5	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.7	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.4	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.3	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.2	GO:0032021	NELF complex(GO:0032021)
0.0	0.5	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.6	GO:1990909	Wnt signalosome(GO:1990909)
0.0	3.4	GO:0015030	Cajal body(GO:0015030)
0.0	0.3	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.4	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0098855	HCN channel complex(GO:0098855)
0.0	0.1	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.0	0.3	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.9	GO:0033268	node of Ranvier(GO:0033268)
0.0	1.4	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.8	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.3	GO:0070187	telosome(GO:0070187)
0.0	4.3	GO:0018995	host(GO:0018995) host cell(GO:0043657)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.4	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.8	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.2	GO:0031417	NatC complex(GO:0031417)
0.0	0.9	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	3.3	GO:0005882	intermediate filament(GO:0005882)
0.0	1.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.3	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0	0.5	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.2	GO:0017102	methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0	0.6	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.2	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.7	GO:0005922	connexon complex(GO:0005922)
0.0	0.4	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.4	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.3	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.2	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	1.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.8	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.3	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	1.4	GO:0031941	filamentous actin(GO:0031941)
0.0	0.4	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.2	GO:0005787	signal peptidase complex(GO:0005787)
0.0	4.4	GO:0043197	dendritic spine(GO:0043197)
0.0	0.4	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.4	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.4	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.5	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.4	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.4	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.0	0.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.3	GO:0044453	nuclear membrane part(GO:0044453)
0.0	0.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:0000439	core TFIIH complex(GO:0000439)
0.0	2.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.1	GO:0019012	virion(GO:0019012) virion part(GO:0044423)
0.0	0.4	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	1.1	GO:0005884	actin filament(GO:0005884)
0.0	0.3	GO:0031143	pseudopodium(GO:0031143)
0.0	0.4	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.4	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0000801	central element(GO:0000801)
0.0	0.2	GO:0090543	Flemming body(GO:0090543)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.8	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	2.1	GO:0043296	apical junction complex(GO:0043296)
0.0	2.9	GO:0001726	ruffle(GO:0001726)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0036019	endolysosome(GO:0036019)
0.0	2.5	GO:0043209	myelin sheath(GO:0043209)
0.0	0.3	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	0.2	GO:0045120	pronucleus(GO:0045120)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.3	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.7	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.2	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.4	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.3	GO:0071141	SMAD protein complex(GO:0071141)
0.0	2.3	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	5.6	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
1.1	12.2	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4	2.9	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.3	2.4	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.3	0.8	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.2	0.9	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2	0.6	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2	1.6	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2	0.5	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
0.2	1.3	GO:0042296	ISG15 transferase activity(GO:0042296)
0.2	0.5	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
0.1	0.4	GO:0031780	corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1	1.1	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.1	0.4	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.1	2.6	GO:0005549	odorant binding(GO:0005549)
0.1	0.4	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.1	0.7	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1	1.8	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.1	0.4	GO:0043337	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1	0.4	GO:0031862	prostanoid receptor binding(GO:0031862)
0.1	0.7	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	0.8	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.1	0.6	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	2.5	GO:0051400	BH domain binding(GO:0051400)
0.1	0.5	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.1	0.9	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.3	GO:0035276	ethanol binding(GO:0035276)
0.1	1.0	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.4	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.1	0.3	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.1	0.7	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.8	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.1	3.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.4	GO:0015389	pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1	0.3	GO:0015403	thiamine uptake transmembrane transporter activity(GO:0015403)
0.1	0.8	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.3	GO:0004947	bradykinin receptor activity(GO:0004947)
0.1	0.4	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	0.2	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.1	0.3	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	0.9	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	1.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	0.4	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.1	0.5	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.1	0.3	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1	0.3	GO:0004743	pyruvate kinase activity(GO:0004743)
0.1	0.4	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.2	GO:0070283	lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1	0.8	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.4	GO:0017040	ceramidase activity(GO:0017040)
0.1	0.9	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.2	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1	0.5	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.7	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.3	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.1	0.3	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	10.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.2	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.1	1.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	1.0	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	1.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.8	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1	0.9	GO:0031433	telethonin binding(GO:0031433)
0.1	0.3	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.5	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	2.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.3	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.1	0.5	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	0.7	GO:0031013	troponin I binding(GO:0031013)
0.1	0.4	GO:0070513	death domain binding(GO:0070513)
0.1	0.3	GO:0061714	folic acid receptor activity(GO:0061714)
0.1	0.9	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	0.2	GO:0015616	DNA translocase activity(GO:0015616)
0.1	0.3	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.1	0.3	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.2	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1	0.3	GO:0015086	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1	0.4	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	0.2	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.1	0.4	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	0.3	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.1	0.2	GO:0001002	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1	0.2	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1	0.4	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	1.7	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	1.3	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	0.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	1.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.9	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.1	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0	0.3	GO:0070728	leucine binding(GO:0070728)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.3	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.0	1.0	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	2.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.4	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	1.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.4	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.2	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.8	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.4	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.3	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.2	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	2.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	3.3	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.2	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0	0.7	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.2	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.4	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0019862	IgA binding(GO:0019862)
0.0	0.3	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0047223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0	0.2	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0052870	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0	1.5	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.2	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.0	0.2	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0	1.7	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.0	0.5	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.4	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.3	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.2	GO:0030614	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0	0.4	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0061769	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0	0.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.1	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.1	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.0	0.4	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	1.1	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	0.3	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.3	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.0	0.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.0	0.1	GO:0035473	lipase binding(GO:0035473)
0.0	0.1	GO:0032217	riboflavin transporter activity(GO:0032217)
0.0	0.1	GO:0016503	pheromone receptor activity(GO:0016503)
0.0	0.2	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.2	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	0.1	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.0	0.7	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.3	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.1	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.0	0.2	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.3	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.0	0.6	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.4	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.2	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0	0.0	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.0	0.1	GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0	0.4	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.2	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.2	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0051800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.4	GO:0019841	retinol binding(GO:0019841)
0.0	0.3	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.4	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0008431	vitamin E binding(GO:0008431)
0.0	0.1	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.2	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.5	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.3	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.2	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.6	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0019961	interferon binding(GO:0019961)
0.0	0.3	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.7	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.1	GO:0010348	lithium:proton antiporter activity(GO:0010348)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.2	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.3	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0001855	complement component C4b binding(GO:0001855)
0.0	0.1	GO:0004074	biliverdin reductase activity(GO:0004074)
0.0	0.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.4	GO:0030553	cGMP binding(GO:0030553)
0.0	0.7	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.0	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.7	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.0	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993)
0.0	0.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.2	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	5.8	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.1	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.8	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.3	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.7	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.7	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.5	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	1.7	GO:0101005	ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.7	GO:0030507	spectrin binding(GO:0030507)
0.0	0.4	GO:0005123	death receptor binding(GO:0005123)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.0	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	0.1	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0	0.0	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	0.3	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	1.1	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.4	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.2	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	1.1	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.3	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.1	GO:0030348	syntaxin-3 binding(GO:0030348)
0.0	0.1	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.4	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.5	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.3	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.2	GO:0032183	SUMO binding(GO:0032183)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.0	GO:0016855	racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0	0.0	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.5	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	2.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	2.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	3.1	PID BARD1 PATHWAY	BARD1 signaling events
0.1	3.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	0.8	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	5.4	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.7	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.5	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	2.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	2.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	2.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	8.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.3	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	1.6	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.5	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.8	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.4	PID BMP PATHWAY	BMP receptor signaling
0.0	0.8	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.7	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.5	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.2	14.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	2.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.8	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	4.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	0.8	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	3.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.8	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	0.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.9	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	1.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.7	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.1	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.7	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	1.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.4	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.7	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.6	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	2.5	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	1.0	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.9	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.3	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.5	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade

Results for DLX4_HOXD8

Z-value: 1.14

Motif logo

Transcription factors associated with DLX4_HOXD8

Activity-expression correlation:

Activity profile of DLX4_HOXD8 motif

Sorted Z-values of DLX4_HOXD8 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX4_HOXD8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: