Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for DLX5

Z-value: 0.32

Motif logo

logo of

Transcription factors associated with DLX5

Gene Symbol Gene ID Gene Info
DLX5
ENSG00000105880.4 distal-less homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DLX5hg19_v2_chr7_-_96654133_96654409-0.029.2e-01Click!

Activity profile of DLX5 motif

Sorted Z-values of DLX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_14785622 0.43 ENST00000443157.2
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr19_-_14785674 0.42 ENST00000253673.5
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr12_-_10151773 0.42 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr19_-_14785698 0.41 ENST00000344373.4
ENST00000595472.1
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr11_-_102651343 0.39 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr8_-_10512569 0.26 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr17_+_43238438 0.24 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr17_+_59489112 0.18 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr15_+_89164520 0.18 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr12_+_7014126 0.17 ENST00000415834.1
ENST00000436789.1
LRRC23
leucine rich repeat containing 23
chr8_-_22526597 0.15 ENST00000519513.1
ENST00000276416.6
ENST00000520292.1
ENST00000522268.1
BIN3
bridging integrator 3
chr8_+_32579341 0.15 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr14_+_32798462 0.14 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr6_+_27861190 0.14 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr14_-_68283291 0.13 ENST00000555452.1
ENST00000347230.4
ZFYVE26
zinc finger, FYVE domain containing 26
chr18_+_55888767 0.11 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_+_101003687 0.11 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr14_+_32798547 0.10 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr14_-_95236551 0.10 ENST00000238558.3
GSC
goosecoid homeobox
chr12_-_53171128 0.10 ENST00000332411.2
KRT76
keratin 76
chr1_-_23670817 0.10 ENST00000478691.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr4_-_7069760 0.10 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr19_-_19302931 0.09 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr19_+_58570605 0.09 ENST00000359978.6
ENST00000401053.4
ENST00000439855.2
ENST00000313434.5
ENST00000511556.1
ENST00000506786.1
ZNF135
zinc finger protein 135
chr22_-_30960876 0.09 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr4_-_66536196 0.09 ENST00000511294.1
EPHA5
EPH receptor A5
chr11_-_71823266 0.08 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr1_+_160160346 0.08 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_202317815 0.08 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr1_-_23670752 0.08 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr1_+_160160283 0.08 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr7_+_97736197 0.08 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr19_-_36606181 0.08 ENST00000221859.4
POLR2I
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
chr8_-_7332604 0.08 ENST00000316169.2
DEFB104B
defensin, beta 104B
chr5_-_160279207 0.08 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr10_-_99205607 0.08 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr16_+_58010339 0.07 ENST00000290871.5
ENST00000441824.2
TEPP
testis, prostate and placenta expressed
chr4_-_143767428 0.07 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr18_-_44181442 0.07 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr10_-_56560939 0.07 ENST00000373955.1
PCDH15
protocadherin-related 15
chr2_+_196313239 0.06 ENST00000413290.1
AC064834.1
AC064834.1
chr1_-_23670813 0.06 ENST00000374612.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr9_+_34646651 0.06 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chr5_-_58571935 0.06 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_99716952 0.06 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr19_+_4007644 0.06 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr4_-_39979576 0.06 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr11_-_71823715 0.06 ENST00000545944.1
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr11_-_26593649 0.06 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr7_+_70597109 0.06 ENST00000333538.5
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr1_+_202317855 0.06 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr11_-_26593779 0.06 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr21_-_15918618 0.05 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr2_-_183387283 0.05 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr6_+_123038689 0.05 ENST00000354275.2
ENST00000368446.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr11_+_118398178 0.05 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr18_-_33709268 0.05 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr11_-_26593677 0.05 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr19_+_36605850 0.05 ENST00000221855.3
TBCB
tubulin folding cofactor B
chr17_-_37009882 0.05 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
RPL23
ribosomal protein L23
chr9_+_34646624 0.04 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr7_-_99717463 0.04 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr11_-_26743546 0.04 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr4_-_105416039 0.04 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr10_-_56561022 0.04 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
PCDH15
protocadherin-related 15
chr12_-_57039739 0.04 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr19_+_36606354 0.04 ENST00000589996.1
ENST00000591296.1
TBCB
tubulin folding cofactor B
chr15_+_41913690 0.04 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chrX_+_100645812 0.04 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr1_-_150669500 0.03 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr11_+_73498898 0.03 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr7_+_100770328 0.03 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr3_+_186288454 0.03 ENST00000265028.3
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chrX_-_16887963 0.03 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr1_+_54569968 0.03 ENST00000391366.1
AL161915.1
Uncharacterized protein
chr1_-_197115818 0.03 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr3_+_11178779 0.03 ENST00000438284.2
HRH1
histamine receptor H1
chr10_+_99205894 0.02 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
ZDHHC16
zinc finger, DHHC-type containing 16
chr3_+_158519654 0.02 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chr3_+_186560476 0.02 ENST00000320741.2
ENST00000444204.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr3_+_186560462 0.02 ENST00000412955.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr7_+_99717230 0.02 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr2_-_172290482 0.02 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
METTL8
methyltransferase like 8
chr9_+_116225999 0.02 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr10_+_99205959 0.02 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16
zinc finger, DHHC-type containing 16
chr7_-_86849883 0.02 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr4_+_77356248 0.02 ENST00000296043.6
SHROOM3
shroom family member 3
chr6_-_33160231 0.02 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr5_-_42811986 0.01 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr2_+_105050794 0.01 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr1_-_150669604 0.01 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr2_+_169757750 0.01 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2
glucose-6-phosphatase, catalytic, 2
chr3_-_52567792 0.01 ENST00000307092.4
ENST00000422318.2
ENST00000459839.1
NT5DC2
5'-nucleotidase domain containing 2
chr8_+_92261516 0.01 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr6_-_27860956 0.01 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr1_-_114447412 0.01 ENST00000369567.1
ENST00000369566.3
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr14_+_24540046 0.01 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6
copine VI (neuronal)
chr12_-_10978957 0.01 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr17_-_47785504 0.01 ENST00000514907.1
ENST00000503334.1
ENST00000508520.1
SLC35B1
solute carrier family 35, member B1
chr12_+_81110684 0.01 ENST00000228644.3
MYF5
myogenic factor 5
chr14_-_24711865 0.00 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr1_-_201140673 0.00 ENST00000367333.2
TMEM9
transmembrane protein 9
chr14_-_24711806 0.00 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.0 GO:0097018 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.0 GO:0001300 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix