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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for DMBX1

Z-value: 0.37

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Transcription factors associated with DMBX1

Gene Symbol Gene ID Gene Info
DMBX1
ENSG00000197587.6 diencephalon/mesencephalon homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DMBX1hg19_v2_chr1_+_46972668_46972669-0.174.3e-01Click!

Activity profile of DMBX1 motif

Sorted Z-values of DMBX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_137851220 0.38 ENST00000236709.3
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr2_-_165812028 0.26 ENST00000303735.4
SLC38A11
solute carrier family 38, member 11
chr2_-_165811983 0.26 ENST00000409058.1
ENST00000409149.3
SLC38A11
solute carrier family 38, member 11
chr19_-_6459746 0.26 ENST00000301454.4
ENST00000334510.5
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr12_-_10959892 0.23 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chrX_-_102565932 0.21 ENST00000372674.1
ENST00000372677.3
BEX2
brain expressed X-linked 2
chr2_-_70780572 0.18 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr12_-_56727676 0.18 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_-_165811756 0.18 ENST00000409662.1
SLC38A11
solute carrier family 38, member 11
chr12_+_53693812 0.18 ENST00000549488.1
C12orf10
chromosome 12 open reading frame 10
chrX_-_32173579 0.17 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr12_-_56727487 0.17 ENST00000548043.1
ENST00000425394.2
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr20_+_59654146 0.17 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr3_+_188664988 0.16 ENST00000433971.1
TPRG1
tumor protein p63 regulated 1
chr3_-_49058479 0.16 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chr1_-_13452656 0.16 ENST00000376132.3
PRAMEF13
PRAME family member 13
chr1_+_162351503 0.15 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr4_+_619347 0.15 ENST00000255622.6
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr12_-_118628350 0.15 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr6_+_130339710 0.13 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr11_+_61248583 0.13 ENST00000432063.2
ENST00000338608.2
PPP1R32
protein phosphatase 1, regulatory subunit 32
chr4_-_54232144 0.13 ENST00000388940.4
ENST00000503450.1
ENST00000401642.3
SCFD2
sec1 family domain containing 2
chr12_-_56321397 0.13 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chr7_+_21582638 0.13 ENST00000409508.3
ENST00000328843.6
DNAH11
dynein, axonemal, heavy chain 11
chr1_-_94586651 0.13 ENST00000535735.1
ENST00000370225.3
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr13_-_62001982 0.13 ENST00000409186.1
PCDH20
protocadherin 20
chr4_-_170679024 0.12 ENST00000393381.2
C4orf27
chromosome 4 open reading frame 27
chr3_-_121468513 0.12 ENST00000494517.1
ENST00000393667.3
GOLGB1
golgin B1
chr5_+_175740083 0.12 ENST00000332772.4
SIMC1
SUMO-interacting motifs containing 1
chr10_-_101491828 0.12 ENST00000370483.5
ENST00000016171.5
COX15
cytochrome c oxidase assembly homolog 15 (yeast)
chr7_+_1727755 0.12 ENST00000424383.2
ELFN1
extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr3_+_138340049 0.12 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr3_-_121468602 0.11 ENST00000340645.5
GOLGB1
golgin B1
chr10_+_103986085 0.11 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr3_+_138340067 0.10 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr14_+_50234309 0.10 ENST00000298307.5
KLHDC2
kelch domain containing 2
chr2_-_14541060 0.10 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr7_-_135412925 0.09 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr19_+_41284121 0.09 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B
RAB4B, member RAS oncogene family
chr12_+_115800817 0.09 ENST00000547948.1
RP11-116D17.1
HCG2038717; Uncharacterized protein
chr6_-_111927062 0.09 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr17_+_4643337 0.09 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr3_-_196242233 0.08 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr16_-_31076273 0.08 ENST00000426488.2
ZNF668
zinc finger protein 668
chr1_+_120839005 0.08 ENST00000369390.3
ENST00000452190.1
FAM72B
family with sequence similarity 72, member B
chr17_+_4643300 0.08 ENST00000433935.1
ZMYND15
zinc finger, MYND-type containing 15
chr17_-_19651654 0.08 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr12_-_56321649 0.08 ENST00000454792.2
ENST00000408946.2
WIBG
within bgcn homolog (Drosophila)
chr11_-_45940343 0.08 ENST00000532681.1
PEX16
peroxisomal biogenesis factor 16
chr17_-_19651668 0.07 ENST00000494157.2
ENST00000225740.6
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr1_+_206138457 0.07 ENST00000367128.3
ENST00000431655.2
FAM72A
family with sequence similarity 72, member A
chr6_-_26250835 0.07 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr4_+_140586922 0.07 ENST00000265498.1
ENST00000506797.1
MGST2
microsomal glutathione S-transferase 2
chr16_-_31076332 0.07 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr1_-_143913143 0.06 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr19_-_17186229 0.06 ENST00000253669.5
ENST00000448593.2
HAUS8
HAUS augmin-like complex, subunit 8
chr3_-_149470229 0.06 ENST00000473414.1
COMMD2
COMM domain containing 2
chr10_-_35104185 0.06 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr4_+_619386 0.06 ENST00000496514.1
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr19_-_17185848 0.06 ENST00000593360.1
HAUS8
HAUS augmin-like complex, subunit 8
chr17_-_4643114 0.05 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chrX_-_71792477 0.05 ENST00000421523.1
ENST00000415409.1
ENST00000373559.4
ENST00000373556.3
ENST00000373560.2
ENST00000373583.1
ENST00000429103.2
ENST00000373571.1
ENST00000373554.1
HDAC8
histone deacetylase 8
chr3_-_19975665 0.05 ENST00000295824.9
ENST00000389256.4
EFHB
EF-hand domain family, member B
chr17_+_68100989 0.04 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr20_+_34556488 0.04 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
CNBD2
cyclic nucleotide binding domain containing 2
chr17_-_48207157 0.04 ENST00000330175.4
ENST00000503131.1
SAMD14
sterile alpha motif domain containing 14
chr19_-_51538118 0.04 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr2_+_37571845 0.04 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr3_-_16524357 0.04 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr15_-_61521495 0.03 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr19_-_51538148 0.03 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr1_-_16563641 0.03 ENST00000375599.3
RSG1
REM2 and RAB-like small GTPase 1
chr17_+_60536002 0.03 ENST00000582809.1
TLK2
tousled-like kinase 2
chr6_-_138893661 0.03 ENST00000427025.2
NHSL1
NHS-like 1
chrX_-_48931648 0.03 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr21_-_35016231 0.02 ENST00000438788.1
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr6_+_89791507 0.02 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr1_+_12851545 0.02 ENST00000332296.7
PRAMEF1
PRAME family member 1
chr17_+_48911942 0.02 ENST00000426127.1
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr19_+_17448348 0.02 ENST00000324894.8
ENST00000358792.7
ENST00000600625.1
GTPBP3
GTP binding protein 3 (mitochondrial)
chr12_-_103310987 0.02 ENST00000307000.2
PAH
phenylalanine hydroxylase
chr2_+_73461410 0.02 ENST00000399032.2
ENST00000398422.2
ENST00000537131.1
ENST00000538797.1
CCT7
chaperonin containing TCP1, subunit 7 (eta)
chr9_+_74920335 0.02 ENST00000451596.2
ENST00000436054.1
RP11-63P12.6
RP11-63P12.6
chr2_+_73461364 0.02 ENST00000540468.1
ENST00000539919.1
ENST00000258091.5
CCT7
chaperonin containing TCP1, subunit 7 (eta)
chr3_+_49058444 0.02 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr9_+_74920408 0.02 ENST00000451152.1
RP11-63P12.6
RP11-63P12.6
chr12_-_110937351 0.02 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr4_-_120225600 0.02 ENST00000399075.4
C4orf3
chromosome 4 open reading frame 3
chr3_+_49057876 0.02 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr19_+_36157715 0.02 ENST00000379013.2
ENST00000222275.2
UPK1A
uroplakin 1A
chr3_-_10362725 0.01 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
SEC13
SEC13 homolog (S. cerevisiae)
chr15_-_60771280 0.01 ENST00000560072.1
ENST00000560406.1
ENST00000560520.1
ENST00000261520.4
ENST00000439632.1
NARG2
NMDA receptor regulated 2
chr12_+_7941989 0.01 ENST00000229307.4
NANOG
Nanog homeobox
chr1_+_35734562 0.00 ENST00000314607.6
ENST00000373297.2
ZMYM4
zinc finger, MYM-type 4
chr18_+_5748793 0.00 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
RP11-945C19.1

Network of associatons between targets according to the STRING database.

First level regulatory network of DMBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.0 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.0 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)