Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for DPRX

Z-value: 0.62

Motif logo

Transcription factors associated with DPRX

Gene Symbol Gene ID Gene Info
ENSG00000204595.1 divergent-paired related homeobox

Activity profile of DPRX motif

Sorted Z-values of DPRX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_169079823 3.18 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr12_+_113344755 2.97 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_-_184943610 2.35 ENST00000367511.3
family with sequence similarity 129, member A
chr8_+_54764346 2.04 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr12_+_113344582 1.94 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_-_153521597 1.77 ENST00000368712.1
S100 calcium binding protein A3
chr1_-_150208320 1.64 ENST00000534220.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_153521714 1.57 ENST00000368713.3
S100 calcium binding protein A3
chr17_+_77021702 1.40 ENST00000392445.2
ENST00000354124.3
C1q and tumor necrosis factor related protein 1
chr12_+_113344811 1.16 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr5_+_35856951 1.14 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
interleukin 7 receptor
chr6_-_35480640 1.07 ENST00000428978.1
ENST00000322263.4
tubby like protein 1
chr4_+_89299885 1.07 ENST00000380265.5
ENST00000273960.3
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr1_+_15986364 0.97 ENST00000345034.1
regulatory solute carrier protein, family 1, member 1
chr1_-_173174681 0.95 ENST00000367718.1
tumor necrosis factor (ligand) superfamily, member 4
chr7_+_28452130 0.89 ENST00000357727.2
cAMP responsive element binding protein 5
chr6_-_37225391 0.88 ENST00000356757.2
transmembrane protein 217
chr6_-_37225367 0.87 ENST00000336655.2
transmembrane protein 217
chr8_+_104384616 0.85 ENST00000520337.1
collagen triple helix repeat containing 1
chr5_-_150460914 0.77 ENST00000389378.2
TNFAIP3 interacting protein 1
chr11_-_104905840 0.72 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr2_+_232063436 0.65 ENST00000440107.1
armadillo repeat containing 9
chr6_+_31554826 0.63 ENST00000376089.2
ENST00000396112.2
leukocyte specific transcript 1
chr6_+_31555045 0.59 ENST00000396101.3
ENST00000490742.1
leukocyte specific transcript 1
chr11_+_61957687 0.57 ENST00000306238.3
secretoglobin, family 1D, member 1
chr6_+_26383404 0.57 ENST00000416795.2
ENST00000494184.1
butyrophilin, subfamily 2, member A2
chr9_+_109625378 0.57 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
zinc finger protein 462
chr11_+_61248583 0.56 ENST00000432063.2
ENST00000338608.2
protein phosphatase 1, regulatory subunit 32
chr16_-_74734742 0.54 ENST00000308807.7
ENST00000573267.1
mixed lineage kinase domain-like
chr6_+_4706368 0.54 ENST00000328908.5
chromodomain protein, Y-like
chr5_-_124081008 0.53 ENST00000306315.5
zinc finger protein 608
chr6_-_35480705 0.53 ENST00000229771.6
tubby like protein 1
chr6_-_33290580 0.49 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
death-domain associated protein
chr9_-_22009297 0.49 ENST00000276925.6
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr10_+_74451883 0.48 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr4_-_170924888 0.48 ENST00000502832.1
ENST00000393704.3
microfibrillar-associated protein 3-like
chr1_-_150780757 0.47 ENST00000271651.3
cathepsin K
chr1_+_50569575 0.46 ENST00000371827.1
ELAV like neuron-specific RNA binding protein 4
chr2_-_49381646 0.45 ENST00000346173.3
ENST00000406846.2
follicle stimulating hormone receptor
chr2_-_49381572 0.45 ENST00000454032.1
ENST00000304421.4
follicle stimulating hormone receptor
chr6_+_26383318 0.44 ENST00000469230.1
ENST00000490025.1
ENST00000356709.4
ENST00000352867.2
ENST00000493275.1
ENST00000472507.1
ENST00000482536.1
ENST00000432533.2
ENST00000482842.1
butyrophilin, subfamily 2, member A2
chr1_+_179561011 0.43 ENST00000294848.8
ENST00000444136.1
tudor domain containing 5
chr5_-_59064458 0.42 ENST00000502575.1
ENST00000507116.1
phosphodiesterase 4D, cAMP-specific
chr6_+_7108210 0.42 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr20_+_361890 0.39 ENST00000449710.1
ENST00000422053.2
tribbles pseudokinase 3
chr1_+_20396649 0.38 ENST00000375108.3
phospholipase A2, group V
chr16_-_30022735 0.38 ENST00000564944.1
double C2-like domains, alpha
chr6_+_37225540 0.38 ENST00000373491.3
TBC1 domain family, member 22B
chrX_+_153448107 0.37 ENST00000369935.5
opsin 1 (cone pigments), medium-wave-sensitive
chr12_+_113416265 0.36 ENST00000449768.2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr1_-_170043709 0.36 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
kinesin-associated protein 3
chr4_-_103997862 0.35 ENST00000394785.3
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr12_-_71182695 0.35 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr6_-_132967142 0.34 ENST00000275216.1
trace amine associated receptor 1
chr19_+_36132631 0.33 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ets variant 2
chr3_+_111393659 0.33 ENST00000477665.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr11_-_104972158 0.33 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr18_-_64271363 0.33 ENST00000262150.2
cadherin 19, type 2
chr3_-_112564797 0.33 ENST00000398214.1
ENST00000448932.1
CD200 receptor 1-like
chr7_+_134464376 0.33 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr16_-_74734672 0.33 ENST00000306247.7
ENST00000575686.1
mixed lineage kinase domain-like
chrX_+_15767971 0.31 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr15_+_63481668 0.31 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B, member RAS oncogene family
chr3_+_130650738 0.31 ENST00000504612.1
ATPase, Ca++ transporting, type 2C, member 1
chr7_+_134576317 0.31 ENST00000424922.1
ENST00000495522.1
caldesmon 1
chr20_+_8112824 0.31 ENST00000378641.3
phospholipase C, beta 1 (phosphoinositide-specific)
chr9_+_37667978 0.31 ENST00000539465.1
FERM and PDZ domain containing 1
chr5_+_140345820 0.31 ENST00000289269.5
protocadherin alpha subfamily C, 2
chr3_+_63953415 0.30 ENST00000484332.1
ataxin 7
chr19_+_36157715 0.30 ENST00000379013.2
ENST00000222275.2
uroplakin 1A
chr4_-_103998060 0.30 ENST00000339611.4
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr2_+_234216454 0.30 ENST00000447536.1
ENST00000409110.1
S-antigen; retina and pineal gland (arrestin)
chr4_-_103998439 0.29 ENST00000503230.1
ENST00000503818.1
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr11_-_85430204 0.29 ENST00000389958.3
ENST00000527794.1
synaptotagmin-like 2
chr11_-_85430163 0.28 ENST00000529581.1
ENST00000533577.1
synaptotagmin-like 2
chr3_+_111393501 0.28 ENST00000393934.3
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr11_-_85430088 0.28 ENST00000533057.1
ENST00000533892.1
synaptotagmin-like 2
chr5_+_63461642 0.28 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
ring finger protein 180
chr11_+_120973375 0.28 ENST00000264037.2
tectorin alpha
chr2_-_235405168 0.28 ENST00000339728.3
ADP-ribosylation factor-like 4C
chr1_+_12916941 0.28 ENST00000240189.2
PRAME family member 2
chr12_-_113574028 0.26 ENST00000546530.1
ENST00000261729.5
RAS protein activator like 1 (GAP1 like)
chr7_+_134576151 0.26 ENST00000393118.2
caldesmon 1
chr18_-_64271316 0.26 ENST00000540086.1
ENST00000580157.1
cadherin 19, type 2
chr7_+_134464414 0.26 ENST00000361901.2
caldesmon 1
chr1_-_13452656 0.26 ENST00000376132.3
PRAME family member 13
chr2_+_69201705 0.25 ENST00000377938.2
gastrokine 1
chr2_+_27799389 0.25 ENST00000408964.2
chromosome 2 open reading frame 16
chr1_+_183441618 0.25 ENST00000507691.2
ENST00000508461.1
ENST00000419169.1
ENST00000347615.2
ENST00000507469.1
ENST00000515829.2
SMG7 nonsense mediated mRNA decay factor
chr1_+_16767167 0.25 ENST00000337132.5
NECAP endocytosis associated 2
chr2_-_30144432 0.25 ENST00000389048.3
anaplastic lymphoma receptor tyrosine kinase
chr1_+_183441500 0.25 ENST00000456731.2
SMG7 nonsense mediated mRNA decay factor
chr3_+_148447887 0.25 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
angiotensin II receptor, type 1
chr17_-_42019836 0.25 ENST00000225992.3
pancreatic polypeptide
chr17_-_15244894 0.24 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
tektin 3
chr19_-_59070239 0.24 ENST00000595957.1
ENST00000253023.3
ubiquitin-conjugating enzyme E2M
chr15_+_34261089 0.24 ENST00000383263.5
cholinergic receptor, muscarinic 5
chr11_-_62752162 0.23 ENST00000458333.2
ENST00000421062.2
solute carrier family 22 (organic anion transporter), member 6
chr1_+_183441600 0.23 ENST00000367537.3
SMG7 nonsense mediated mRNA decay factor
chr14_-_101034407 0.23 ENST00000443071.2
ENST00000557378.1
brain-enriched guanylate kinase-associated
chr10_-_72362515 0.23 ENST00000373209.2
ENST00000441259.1
perforin 1 (pore forming protein)
chr8_-_71520513 0.23 ENST00000262213.2
ENST00000536748.1
ENST00000518678.1
translocation associated membrane protein 1
chr1_-_27481401 0.22 ENST00000263980.3
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chr12_+_124069070 0.22 ENST00000262225.3
ENST00000438031.2
transmembrane emp24 domain trafficking protein 2
chr9_-_132404374 0.21 ENST00000277459.4
ENST00000450050.2
ENST00000277458.4
ankyrin repeat and SOCS box containing 6
chr5_+_169010638 0.21 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
spindle apparatus coiled-coil protein 1
chr19_+_8455077 0.21 ENST00000328024.6
RAB11B, member RAS oncogene family
chr6_-_32908765 0.21 ENST00000416244.2
major histocompatibility complex, class II, DM beta
chr6_-_26108355 0.21 ENST00000338379.4
histone cluster 1, H1t
chr6_+_36164487 0.20 ENST00000357641.6
bromodomain and PHD finger containing, 3
chr4_-_122791583 0.20 ENST00000506636.1
ENST00000264499.4
Bardet-Biedl syndrome 7
chr12_-_110937351 0.20 ENST00000552130.2
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr22_-_43355858 0.20 ENST00000402229.1
ENST00000407585.1
ENST00000453079.1
protein kinase C and casein kinase substrate in neurons 2
chr16_+_21244986 0.20 ENST00000311620.5
ankyrin repeat and sterile alpha motif domain containing 4B
chr17_+_3118915 0.20 ENST00000304094.1
olfactory receptor, family 1, subfamily A, member 1
chr10_-_89577910 0.20 ENST00000308448.7
ENST00000541004.1
ATPase family, AAA domain containing 1
chr9_-_123239632 0.20 ENST00000416449.1
CDK5 regulatory subunit associated protein 2
chr9_+_4839762 0.20 ENST00000448872.2
ENST00000441844.1
RNA terminal phosphate cyclase-like 1
chr11_-_104817919 0.19 ENST00000533252.1
caspase 4, apoptosis-related cysteine peptidase
chr19_-_12267524 0.19 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
zinc finger protein 625
chr18_+_32290218 0.19 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
dystrobrevin, alpha
chr1_+_111415757 0.19 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr16_+_81272287 0.19 ENST00000425577.2
ENST00000564552.1
beta-carotene 15,15'-monooxygenase 1
chr11_-_30608413 0.19 ENST00000528686.1
metallophosphoesterase domain containing 2
chr12_+_54891495 0.18 ENST00000293373.6
NCK-associated protein 1-like
chr2_-_190044480 0.18 ENST00000374866.3
collagen, type V, alpha 2
chr6_+_7107999 0.18 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr1_+_16767195 0.18 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP endocytosis associated 2
chr6_-_22297730 0.18 ENST00000306482.1
prolactin
chr6_-_32908792 0.18 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr1_+_182808474 0.18 ENST00000367549.3
DEAH (Asp-Glu-Ala-His) box helicase 9
chr5_+_180336564 0.18 ENST00000505126.1
ENST00000533815.2
butyrophilin-like 8
chr17_-_9694614 0.18 ENST00000330255.5
ENST00000571134.1
dehydrogenase/reductase (SDR family) member 7C
chr19_-_50370799 0.18 ENST00000600910.1
ENST00000322344.3
ENST00000600573.1
polynucleotide kinase 3'-phosphatase
chr17_+_55183261 0.17 ENST00000576295.1
A kinase (PRKA) anchor protein 1
chr17_+_7531281 0.17 ENST00000575729.1
ENST00000340624.5
sex hormone-binding globulin
chr3_-_124653579 0.17 ENST00000478191.1
ENST00000311075.3
mucin 13, cell surface associated
chr19_+_50528971 0.17 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
zinc finger protein 473
chr3_+_133502877 0.17 ENST00000466490.2
signal recognition particle receptor, B subunit
chr1_-_236046872 0.16 ENST00000536965.1
lysosomal trafficking regulator
chr7_+_123241908 0.16 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ankyrin repeat and SOCS box containing 15
chrX_+_69488174 0.16 ENST00000480877.2
ENST00000307959.8
arrestin 3, retinal (X-arrestin)
chr18_-_3845293 0.15 ENST00000400145.2
discs, large (Drosophila) homolog-associated protein 1
chr21_-_28217721 0.15 ENST00000284984.3
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr2_-_180610767 0.15 ENST00000409343.1
zinc finger protein 385B
chr12_+_104359641 0.15 ENST00000537100.1
thymine-DNA glycosylase
chr11_-_65629497 0.15 ENST00000532134.1
cofilin 1 (non-muscle)
chrX_+_118425471 0.14 ENST00000428222.1
RP5-1139I1.1
chr16_+_30386098 0.14 ENST00000322861.7
myosin light chain, phosphorylatable, fast skeletal muscle
chr8_-_145701718 0.14 ENST00000377317.4
forkhead box H1
chr8_+_65285851 0.14 ENST00000520799.1
ENST00000521441.1
long intergenic non-protein coding RNA 966
chr2_+_113342011 0.14 ENST00000324913.5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr19_+_56165480 0.14 ENST00000450554.2
U2 small nuclear RNA auxiliary factor 2
chr8_-_79717750 0.14 ENST00000263851.4
ENST00000379113.2
interleukin 7
chr11_-_111944895 0.14 ENST00000431456.1
ENST00000280350.4
ENST00000530641.1
PIH1 domain containing 2
chr9_-_123812542 0.14 ENST00000223642.1
complement component 5
chr19_-_50529193 0.14 ENST00000596445.1
ENST00000599538.1
vaccinia related kinase 3
chr13_+_52436111 0.14 ENST00000242819.4
coiled-coil domain containing 70
chr9_-_95244781 0.14 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
asporin
chr11_+_12399071 0.14 ENST00000539723.1
ENST00000550549.1
parvin, alpha
chr2_-_26700900 0.14 ENST00000338581.6
ENST00000339598.3
ENST00000402415.3
otoferlin
chr2_+_113342163 0.14 ENST00000409719.1
coiled-coil-helix-coiled-coil-helix domain containing 5
chr1_+_156117149 0.13 ENST00000435124.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_+_77088989 0.13 ENST00000461745.1
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr14_-_21056121 0.13 ENST00000557105.1
ENST00000398008.2
ENST00000555841.1
ENST00000443456.2
ENST00000432835.2
ENST00000557503.1
ENST00000398009.2
ENST00000554842.1
ribonuclease, RNase A family, 11 (non-active)
chr16_-_46723066 0.13 ENST00000299138.7
vacuolar protein sorting 35 homolog (S. cerevisiae)
chrX_+_71996972 0.13 ENST00000334036.5
DMRT-like family C1B
chr7_-_135412925 0.13 ENST00000354042.4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr15_+_75970672 0.13 ENST00000435356.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr18_-_28681950 0.13 ENST00000251081.6
desmocollin 2
chr12_+_104359614 0.12 ENST00000266775.9
ENST00000544861.1
thymine-DNA glycosylase
chr18_-_28682374 0.12 ENST00000280904.6
desmocollin 2
chr7_-_30066233 0.12 ENST00000222803.5
FK506 binding protein 14, 22 kDa
chr4_-_152149033 0.12 ENST00000514152.1
SH3 domain containing 19
chr1_+_100435315 0.12 ENST00000370155.3
ENST00000465289.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr11_-_10715287 0.12 ENST00000423302.2
murine retrovirus integration site 1 homolog
chr22_-_19137796 0.12 ENST00000086933.2
goosecoid homeobox 2
chr14_-_21055874 0.12 ENST00000553849.1
ribonuclease, RNase A family, 11 (non-active)
chr4_-_153700864 0.12 ENST00000304337.2
tigger transposable element derived 4
chr2_+_145425573 0.12 ENST00000600064.1
ENST00000597670.1
ENST00000414256.1
ENST00000599187.1
ENST00000451774.1
ENST00000599072.1
ENST00000596589.1
ENST00000597893.1
testis expressed 41 (non-protein coding)
chrX_-_53449593 0.12 ENST00000375340.6
ENST00000322213.4
structural maintenance of chromosomes 1A
chr4_-_47465666 0.11 ENST00000381571.4
COMM domain containing 8
chr3_+_141105705 0.11 ENST00000513258.1
zinc finger and BTB domain containing 38
chr10_+_51572408 0.11 ENST00000374082.1
nuclear receptor coactivator 4
chr17_-_48785216 0.11 ENST00000285243.6
ankyrin repeat domain 40
chr6_-_30640811 0.11 ENST00000376442.3
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr12_+_6949964 0.11 ENST00000541978.1
ENST00000435982.2
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr19_-_57967854 0.11 ENST00000321039.3
vomeronasal 1 receptor 1
chr1_+_236557569 0.11 ENST00000334232.4
EDAR-associated death domain
chr3_-_54962100 0.11 ENST00000273286.5
leucine-rich repeats and transmembrane domains 1
chr7_-_75401513 0.11 ENST00000005180.4
chemokine (C-C motif) ligand 26
chr4_+_84377198 0.11 ENST00000507349.1
ENST00000509970.1
ENST00000505719.1
mitochondrial ribosomal protein S18C
chr9_-_22009241 0.11 ENST00000380142.4
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr2_-_119605253 0.11 ENST00000295206.6
engrailed homeobox 1
chr10_+_51572339 0.11 ENST00000344348.6
nuclear receptor coactivator 4
chr5_-_150948414 0.11 ENST00000261800.5
FAT atypical cadherin 2
chr5_+_150040403 0.10 ENST00000517768.1
ENST00000297130.4
myozenin 3
chr3_+_136676851 0.10 ENST00000309741.5
interleukin 20 receptor beta
chr6_-_31080336 0.10 ENST00000259870.3
chromosome 6 open reading frame 15
chr15_+_81475047 0.10 ENST00000559388.1
interleukin 16

Network of associatons between targets according to the STRING database.

First level regulatory network of DPRX

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.3 0.9 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 1.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.9 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.2 0.8 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.6 GO:0080154 regulation of fertilization(GO:0080154)
0.2 1.4 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 1.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.6 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.5 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.1 0.8 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.4 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.9 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.3 GO:0097254 renal tubular secretion(GO:0097254)
0.1 0.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 1.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.8 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.5 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.2 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808) negative regulation of hypersensitivity(GO:0002884)
0.0 0.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.4 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.3 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:1903181 positive regulation of Wnt protein secretion(GO:0061357) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 5.9 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.2 GO:0035546 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.0 0.2 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.4 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 1.6 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.9 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.6 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:0002418 immune response to tumor cell(GO:0002418)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0051105 regulation of DNA ligation(GO:0051105)
0.0 1.2 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 2.0 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 2.0 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.0 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 3.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 0.4 GO:0016939 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.1 1.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.2 GO:0030478 actin cap(GO:0030478)
0.1 0.5 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.4 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 2.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 2.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 1.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 0.9 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.2 0.9 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.2 3.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.5 GO:0002046 opsin binding(GO:0002046)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.1 1.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.6 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 1.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.0 GO:0008200 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.1 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 3.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 6.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.9 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 2.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription