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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for DRGX_PROP1

Z-value: 0.45

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Transcription factors associated with DRGX_PROP1

Gene Symbol Gene ID Gene Info
DRGX
ENSG00000165606.4 dorsal root ganglia homeobox
PROP1
ENSG00000175325.2 PROP paired-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROP1hg19_v2_chr5_-_177423243_1774232430.213.1e-01Click!

Activity profile of DRGX_PROP1 motif

Sorted Z-values of DRGX_PROP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_92371839 2.55 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr6_+_116691001 1.20 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr16_+_68119247 1.07 ENST00000575270.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr6_-_76072719 1.06 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr3_-_18480260 0.89 ENST00000454909.2
SATB1
SATB homeobox 1
chr16_+_68119324 0.81 ENST00000349223.5
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr8_-_93107443 0.81 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_-_52970820 0.79 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr1_+_84630645 0.76 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr16_+_68119440 0.74 ENST00000346183.3
ENST00000329524.4
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chrX_+_77166172 0.69 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr2_-_183291741 0.67 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_+_179184955 0.66 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr1_-_21377383 0.65 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr5_-_111312622 0.61 ENST00000395634.3
NREP
neuronal regeneration related protein
chr14_-_75536182 0.59 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr13_+_53602894 0.56 ENST00000219022.2
OLFM4
olfactomedin 4
chr8_-_93107696 0.55 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_27764190 0.53 ENST00000537516.1
EOMES
eomesodermin
chr4_+_156587853 0.49 ENST00000506455.1
ENST00000511108.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr12_+_19358228 0.48 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr15_+_57511609 0.47 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chr2_+_191334212 0.46 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr18_+_616672 0.45 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr10_-_50396407 0.44 ENST00000374153.2
ENST00000374151.3
C10orf128
chromosome 10 open reading frame 128
chr5_+_61874562 0.43 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr1_-_234667504 0.43 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr18_+_616711 0.42 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr2_-_55496174 0.41 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
MTIF2
mitochondrial translational initiation factor 2
chr9_+_77230499 0.37 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr3_-_124774802 0.37 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr1_-_94147385 0.37 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr17_-_14683517 0.36 ENST00000379640.1
AC005863.1
AC005863.1
chr5_-_54468974 0.36 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr5_+_140571902 0.36 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr1_+_243419306 0.35 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8
serologically defined colon cancer antigen 8
chr5_-_111091948 0.34 ENST00000447165.2
NREP
neuronal regeneration related protein
chr9_+_2159850 0.33 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_58468437 0.33 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chrX_-_19817869 0.32 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr8_+_26150628 0.32 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr21_+_17442799 0.32 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr6_-_111804905 0.31 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr8_+_11961898 0.31 ENST00000400085.3
ZNF705D
zinc finger protein 705D
chr11_-_118122996 0.31 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr18_-_52989217 0.31 ENST00000570287.2
TCF4
transcription factor 4
chr8_-_17752996 0.30 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr3_-_27763803 0.30 ENST00000449599.1
EOMES
eomesodermin
chr12_-_7656357 0.29 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163
CD163 molecule
chr5_-_111093759 0.29 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr3_-_141747950 0.28 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr8_-_17752912 0.28 ENST00000398054.1
ENST00000381840.2
FGL1
fibrinogen-like 1
chr1_-_151148492 0.28 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chr7_+_90338712 0.27 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr18_-_52989525 0.27 ENST00000457482.3
TCF4
transcription factor 4
chr12_+_59989918 0.26 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr16_+_24549014 0.26 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr12_-_118797475 0.25 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr19_-_58485895 0.24 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr17_+_44588877 0.24 ENST00000576629.1
LRRC37A2
leucine rich repeat containing 37, member A2
chr1_+_78383813 0.24 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr9_+_136501478 0.23 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr6_+_30881982 0.23 ENST00000321897.5
ENST00000416670.2
ENST00000542001.1
ENST00000428017.1
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr10_-_75226166 0.22 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr6_+_30882108 0.21 ENST00000541562.1
ENST00000421263.1
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr4_-_100356291 0.21 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_+_107224364 0.21 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr8_-_86253888 0.20 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr17_-_29641084 0.20 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr2_+_179317994 0.20 ENST00000375129.4
DFNB59
deafness, autosomal recessive 59
chrY_-_6742068 0.20 ENST00000215479.5
AMELY
amelogenin, Y-linked
chr1_-_151148442 0.20 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chr8_-_57123815 0.19 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr10_-_50396425 0.19 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chr13_+_57715052 0.18 ENST00000377931.1
PRR20A
proline rich 20A
chr8_-_57472154 0.17 ENST00000499425.1
ENST00000523664.1
ENST00000518943.1
ENST00000524338.1
LINC00968
long intergenic non-protein coding RNA 968
chr22_-_29107919 0.17 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr3_-_197300194 0.17 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr5_-_66492562 0.17 ENST00000256447.4
CD180
CD180 molecule
chr12_+_122688090 0.17 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr2_+_86669118 0.17 ENST00000427678.1
ENST00000542128.1
KDM3A
lysine (K)-specific demethylase 3A
chr3_+_111697843 0.17 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10
abhydrolase domain containing 10
chr10_+_35464513 0.17 ENST00000494479.1
ENST00000463314.1
ENST00000342105.3
ENST00000495301.1
ENST00000463960.1
CREM
cAMP responsive element modulator
chr16_+_81272287 0.17 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr4_-_100356551 0.17 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr5_-_55412774 0.16 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr2_+_32390925 0.16 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr2_+_109237717 0.15 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr5_-_137475071 0.15 ENST00000265191.2
NME5
NME/NM23 family member 5
chrX_+_35937843 0.15 ENST00000297866.5
CXorf22
chromosome X open reading frame 22
chr3_-_165555200 0.14 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr1_+_206557366 0.14 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr12_-_118628350 0.14 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr15_+_43477580 0.14 ENST00000356633.5
CCNDBP1
cyclin D-type binding-protein 1
chr15_+_75628232 0.14 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4
chr1_+_15668240 0.13 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr1_+_244214577 0.13 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr11_+_55029628 0.13 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr16_+_81678957 0.13 ENST00000398040.4
CMIP
c-Maf inducing protein
chr9_-_21351377 0.13 ENST00000380210.1
IFNA6
interferon, alpha 6
chr5_-_134735568 0.13 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr1_+_74701062 0.13 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr6_-_24358264 0.13 ENST00000378454.3
DCDC2
doublecortin domain containing 2
chr7_+_148287657 0.13 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr1_+_3773825 0.12 ENST00000378209.3
ENST00000338895.3
ENST00000378212.2
ENST00000341385.3
DFFB
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr14_-_38064198 0.12 ENST00000250448.2
FOXA1
forkhead box A1
chr4_-_143227088 0.12 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr17_-_71228357 0.12 ENST00000583024.1
ENST00000403627.3
ENST00000405159.3
ENST00000581110.1
FAM104A
family with sequence similarity 104, member A
chr4_-_89951028 0.12 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr6_+_72926145 0.11 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr14_-_36988882 0.11 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chrX_+_107288239 0.11 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr12_-_10151773 0.10 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr10_+_97803151 0.10 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ
cyclin J
chr16_+_53133070 0.10 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr14_-_81425828 0.10 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr17_+_71228740 0.10 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr15_+_75628394 0.10 ENST00000564815.1
ENST00000338995.6
COMMD4
COMM domain containing 4
chr21_+_17792672 0.10 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr6_+_42896865 0.10 ENST00000372836.4
ENST00000394142.3
CNPY3
canopy FGF signaling regulator 3
chr3_-_98241760 0.10 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1
claudin domain containing 1
chr9_-_70465758 0.09 ENST00000489273.1
CBWD5
COBW domain containing 5
chr6_+_26087646 0.09 ENST00000309234.6
HFE
hemochromatosis
chr17_+_71228537 0.09 ENST00000577615.1
ENST00000585109.1
C17orf80
chromosome 17 open reading frame 80
chr12_+_58003935 0.09 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr6_+_3259148 0.09 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr6_+_27791862 0.09 ENST00000355057.1
HIST1H4J
histone cluster 1, H4j
chr2_+_177015950 0.09 ENST00000306324.3
HOXD4
homeobox D4
chr9_-_27005686 0.08 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr11_-_96076334 0.08 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr16_+_89334512 0.08 ENST00000602042.1
AC137932.1
AC137932.1
chr3_-_12587055 0.08 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr5_+_140514782 0.08 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr3_-_157824292 0.08 ENST00000483851.2
SHOX2
short stature homeobox 2
chr7_+_55980331 0.08 ENST00000429591.2
ZNF713
zinc finger protein 713
chr5_+_68860949 0.08 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr10_-_128359074 0.07 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr9_+_42671887 0.07 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr12_+_54422142 0.07 ENST00000243108.4
HOXC6
homeobox C6
chr20_+_31823792 0.07 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1
BPI fold containing family A, member 1
chrX_+_107288197 0.07 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr3_-_33686743 0.07 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr4_+_40198527 0.07 ENST00000381799.5
RHOH
ras homolog family member H
chr1_-_241799232 0.07 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr2_-_172087824 0.07 ENST00000521943.1
TLK1
tousled-like kinase 1
chr5_+_140207536 0.07 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr11_-_102576537 0.07 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr16_-_74700737 0.07 ENST00000576652.1
ENST00000572337.1
ENST00000571750.1
ENST00000572990.1
ENST00000361070.4
RFWD3
ring finger and WD repeat domain 3
chr22_-_27456361 0.07 ENST00000453934.1
CTA-992D9.6
CTA-992D9.6
chr7_-_122840015 0.07 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chrX_+_119737806 0.07 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr17_-_56082455 0.07 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr6_-_150067696 0.07 ENST00000340413.2
ENST00000367403.3
NUP43
nucleoporin 43kDa
chr4_-_143226979 0.07 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_+_69313145 0.07 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr16_-_69373396 0.07 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chrX_+_78200829 0.06 ENST00000544091.1
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr4_+_48485341 0.06 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr12_+_75784850 0.06 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr3_-_156878540 0.06 ENST00000461804.1
CCNL1
cyclin L1
chr12_-_10324716 0.06 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chrX_+_78200913 0.06 ENST00000171757.2
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr5_-_9630463 0.06 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr11_-_40315640 0.06 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr2_+_121010370 0.06 ENST00000420510.1
RALB
v-ral simian leukemia viral oncogene homolog B
chr2_-_208994548 0.06 ENST00000282141.3
CRYGC
crystallin, gamma C
chr2_+_75873902 0.06 ENST00000393909.2
ENST00000358788.6
ENST00000409374.1
MRPL19
mitochondrial ribosomal protein L19
chr2_+_121010324 0.06 ENST00000272519.5
RALB
v-ral simian leukemia viral oncogene homolog B
chr2_-_55237484 0.05 ENST00000394609.2
RTN4
reticulon 4
chr3_-_151034734 0.05 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr19_-_38183201 0.05 ENST00000590008.1
ENST00000358582.4
ZNF781
zinc finger protein 781
chr6_+_3259122 0.05 ENST00000438998.2
ENST00000380305.4
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr17_+_68071458 0.05 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_+_136553370 0.05 ENST00000445907.2
CHRM2
cholinergic receptor, muscarinic 2
chr2_+_128458514 0.05 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr12_-_92539614 0.05 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr3_-_187455680 0.05 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr9_+_21440440 0.05 ENST00000276927.1
IFNA1
interferon, alpha 1
chr1_-_186430222 0.05 ENST00000391997.2
PDC
phosducin
chr17_+_68071389 0.05 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr10_+_695888 0.05 ENST00000441152.2
PRR26
proline rich 26
chr18_-_44181442 0.05 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr1_-_232651312 0.04 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr4_-_139051839 0.04 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
LINC00616
long intergenic non-protein coding RNA 616
chr5_+_140227357 0.04 ENST00000378122.3
PCDHA9
protocadherin alpha 9
chr1_-_242162375 0.04 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr9_+_27524283 0.04 ENST00000276943.2
IFNK
interferon, kappa
chr6_+_88117683 0.04 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr20_+_32150140 0.04 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr16_-_21663919 0.04 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr12_-_75784669 0.04 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2
calcyphosine 2
chr12_-_52946923 0.03 ENST00000267119.5
KRT71
keratin 71
chr8_-_62602327 0.03 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr11_-_111649015 0.03 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr1_-_209957882 0.03 ENST00000294811.1
C1orf74
chromosome 1 open reading frame 74
chr17_+_75181292 0.03 ENST00000431431.2
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr2_+_36923830 0.02 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr2_+_44502597 0.02 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr3_-_32544900 0.02 ENST00000205636.3
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr2_+_166150541 0.02 ENST00000283256.6
SCN2A
sodium channel, voltage-gated, type II, alpha subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of DRGX_PROP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.3 0.8 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.2 0.7 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.4 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 2.6 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.8 GO:0097338 response to clozapine(GO:0097338)
0.1 0.4 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.5 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 0.6 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 0.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 1.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.1 GO:0001928 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.2 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.3 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:1990641 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:1903464 negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 1.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:1900228 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 2.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 0.7 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.6 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.2 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.2 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway