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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for E2F8

Z-value: 0.86

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Transcription factors associated with E2F8

Gene Symbol Gene ID Gene Info
ENSG00000129173.8 E2F transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F8hg19_v2_chr11_-_19263145_192631760.654.2e-04Click!

Activity profile of E2F8 motif

Sorted Z-values of E2F8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_131762105 2.88 ENST00000368648.3
ENST00000355311.5
early B-cell factor 3
chr9_-_74675521 2.34 ENST00000377024.3
chromosome 9 open reading frame 57
chr18_+_72922710 2.26 ENST00000322038.5
teashirt zinc finger homeobox 1
chr7_-_21985489 1.43 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
cell division cycle associated 7-like
chr7_-_21985656 1.41 ENST00000406877.3
cell division cycle associated 7-like
chr2_+_24346324 1.38 ENST00000407625.1
ENST00000420135.2
family with sequence similarity 228, member B
chr18_+_59992527 1.22 ENST00000586569.1
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr14_-_74551096 1.13 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr8_-_81083731 1.08 ENST00000379096.5
tumor protein D52
chr22_+_35796056 1.04 ENST00000216122.4
minichromosome maintenance complex component 5
chr11_-_19263145 1.04 ENST00000532666.1
ENST00000527884.1
E2F transcription factor 8
chr2_-_177502659 1.03 ENST00000295549.4
long intergenic non-protein coding RNA 1116
chr2_-_58468437 1.02 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
Fanconi anemia, complementation group L
chr22_+_35796108 1.01 ENST00000382011.5
ENST00000416905.1
minichromosome maintenance complex component 5
chr10_+_35416090 0.98 ENST00000354759.3
cAMP responsive element modulator
chr2_+_148778570 0.98 ENST00000407073.1
methyl-CpG binding domain protein 5
chr11_+_47236489 0.96 ENST00000256996.4
ENST00000378603.3
ENST00000378600.3
ENST00000378601.3
damage-specific DNA binding protein 2, 48kDa
chr1_+_197871854 0.94 ENST00000436652.1
chromosome 1 open reading frame 53
chr6_-_2962331 0.93 ENST00000380524.1
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr17_+_56769924 0.93 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51 paralog C
chr1_+_158979792 0.91 ENST00000359709.3
ENST00000430894.2
interferon, gamma-inducible protein 16
chr11_-_66445219 0.90 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RNA binding motif protein 4B
chr11_-_89224508 0.90 ENST00000525196.1
NADPH oxidase 4
chr22_+_19467261 0.89 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
cell division cycle 45
chr12_+_124155652 0.86 ENST00000426174.2
ENST00000303372.5
tectonic family member 2
chr12_-_6772303 0.86 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
inhibitor of growth family, member 4
chr7_-_56119238 0.83 ENST00000275605.3
ENST00000395471.3
phosphoserine phosphatase
chr18_+_59992514 0.83 ENST00000269485.7
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr12_-_15942503 0.83 ENST00000281172.5
epidermal growth factor receptor pathway substrate 8
chr8_+_29952914 0.83 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
leptin receptor overlapping transcript-like 1
chr12_+_123011776 0.83 ENST00000450485.2
ENST00000333479.7
kinetochore associated 1
chr3_+_127317066 0.81 ENST00000265056.7
minichromosome maintenance complex component 2
chr12_-_15942309 0.80 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
epidermal growth factor receptor pathway substrate 8
chr1_+_70876926 0.76 ENST00000370938.3
ENST00000346806.2
cystathionase (cystathionine gamma-lyase)
chr16_-_67185117 0.76 ENST00000449549.3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr14_-_74551172 0.76 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chrX_+_10031499 0.75 ENST00000454666.1
WWC family member 3
chr2_-_136633940 0.74 ENST00000264156.2
minichromosome maintenance complex component 6
chr11_+_9595180 0.74 ENST00000450114.2
WEE1 G2 checkpoint kinase
chr6_-_111804905 0.72 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr3_+_122296443 0.70 ENST00000464300.2
poly (ADP-ribose) polymerase family, member 15
chr11_+_47586982 0.69 ENST00000426530.2
ENST00000534775.1
protein tyrosine phosphatase, mitochondrial 1
chrX_-_54522558 0.69 ENST00000375135.3
FYVE, RhoGEF and PH domain containing 1
chr13_+_21277482 0.68 ENST00000304920.3
interleukin 17D
chr12_+_107168418 0.68 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8 guanine nucleotide exchange factor B
chr4_+_108910870 0.68 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
hydroxyacyl-CoA dehydrogenase
chrX_-_119695279 0.67 ENST00000336592.6
cullin 4B
chr12_-_57146095 0.67 ENST00000550770.1
ENST00000338193.6
primase, DNA, polypeptide 1 (49kDa)
chr8_+_118533049 0.66 ENST00000522839.1
mediator complex subunit 30
chr11_-_19262486 0.65 ENST00000250024.4
E2F transcription factor 8
chr10_-_95360983 0.65 ENST00000371464.3
retinol binding protein 4, plasma
chr12_+_3069037 0.64 ENST00000397122.2
TEA domain family member 4
chr8_+_29953163 0.64 ENST00000518192.1
leptin receptor overlapping transcript-like 1
chr2_+_16080659 0.64 ENST00000281043.3
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr11_+_47587129 0.64 ENST00000326656.8
ENST00000326674.9
protein tyrosine phosphatase, mitochondrial 1
chr10_+_35416223 0.63 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr8_+_118532937 0.63 ENST00000297347.3
mediator complex subunit 30
chr8_-_92053212 0.62 ENST00000285419.3
transmembrane protein 55A
chr16_+_56995854 0.62 ENST00000566128.1
cholesteryl ester transfer protein, plasma
chr12_-_102455846 0.61 ENST00000545679.1
coiled-coil domain containing 53
chr7_+_26331541 0.61 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
sorting nexin 10
chr12_+_56661461 0.60 ENST00000546544.1
ENST00000553234.1
coenzyme Q10 homolog A (S. cerevisiae)
chr17_+_66243715 0.60 ENST00000359904.3
archaelysin family metallopeptidase 2
chr6_-_32157947 0.59 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr9_+_130374537 0.59 ENST00000373302.3
ENST00000373299.1
syntaxin binding protein 1
chr1_+_197871740 0.57 ENST00000367393.3
chromosome 1 open reading frame 53
chr7_+_100136811 0.56 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chrX_-_135338503 0.55 ENST00000370663.5
MAP7 domain containing 3
chr1_-_6295975 0.54 ENST00000343813.5
ENST00000362035.3
isoprenylcysteine carboxyl methyltransferase
chr7_-_56118981 0.54 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
phosphoserine phosphatase
chrX_+_55026763 0.53 ENST00000374987.3
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr12_-_102455902 0.53 ENST00000240079.6
coiled-coil domain containing 53
chr2_+_10262857 0.53 ENST00000304567.5
ribonucleotide reductase M2
chr19_-_51845378 0.52 ENST00000335624.4
V-set and immunoglobulin domain containing 10 like
chrX_-_10588459 0.52 ENST00000380782.2
midline 1 (Opitz/BBB syndrome)
chr5_+_31532373 0.52 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
chromosome 5 open reading frame 22
chr12_+_56521840 0.52 ENST00000394048.5
extended synaptotagmin-like protein 1
chr1_+_70876891 0.52 ENST00000411986.2
cystathionase (cystathionine gamma-lyase)
chr16_+_56995762 0.51 ENST00000200676.3
ENST00000379780.2
cholesteryl ester transfer protein, plasma
chr1_+_97187318 0.50 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
polypyrimidine tract binding protein 2
chrX_-_129299847 0.50 ENST00000319908.3
ENST00000287295.3
apoptosis-inducing factor, mitochondrion-associated, 1
chr1_+_201798269 0.50 ENST00000361565.4
importin 9
chrX_-_10588595 0.49 ENST00000423614.1
ENST00000317552.4
midline 1 (Opitz/BBB syndrome)
chr15_-_57025759 0.49 ENST00000267807.7
zinc finger protein 280D
chr7_-_56119156 0.49 ENST00000421312.1
ENST00000416592.1
phosphoserine phosphatase
chr2_-_70780572 0.48 ENST00000450929.1
transforming growth factor, alpha
chr17_-_9479128 0.47 ENST00000574431.1
syntaxin 8
chr12_-_71003568 0.47 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
protein tyrosine phosphatase, receptor type, B
chr9_+_131445928 0.47 ENST00000372692.4
SET nuclear oncogene
chr17_-_60005365 0.45 ENST00000444766.3
integrator complex subunit 2
chr4_-_57844989 0.45 ENST00000264230.4
nitric oxide associated 1
chr1_+_156024552 0.45 ENST00000368304.5
ENST00000368302.3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr17_-_46623441 0.45 ENST00000330070.4
homeobox B2
chr17_-_59940830 0.44 ENST00000259008.2
BRCA1 interacting protein C-terminal helicase 1
chr9_+_99690592 0.44 ENST00000354649.3
NUT family member 2G
chr2_-_130956006 0.43 ENST00000312988.7
tubulin, alpha 3e
chr12_+_56324933 0.43 ENST00000549629.1
ENST00000555218.1
diacylglycerol kinase, alpha 80kDa
chr10_+_115312766 0.42 ENST00000351270.3
hyaluronan binding protein 2
chr16_-_18812746 0.42 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr4_-_174254823 0.41 ENST00000438704.2
high mobility group box 2
chr17_-_30668887 0.41 ENST00000581747.1
ENST00000583334.1
ENST00000580558.1
chromosome 17 open reading frame 75
chr22_-_19974616 0.41 ENST00000344269.3
ENST00000401994.1
ENST00000406522.1
armadillo repeat gene deleted in velocardiofacial syndrome
chr8_+_48873479 0.41 ENST00000262105.2
minichromosome maintenance complex component 4
chr14_+_105992906 0.40 ENST00000392519.2
transmembrane protein 121
chr4_-_39367949 0.39 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
replication factor C (activator 1) 1, 145kDa
chr20_+_31595406 0.39 ENST00000170150.3
BPI fold containing family B, member 2
chr6_+_127588020 0.39 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
ring finger protein 146
chr8_+_48873453 0.39 ENST00000523944.1
minichromosome maintenance complex component 4
chr15_-_64385981 0.38 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
family with sequence similarity 96, member A
chr12_+_107168342 0.38 ENST00000392837.4
RIC8 guanine nucleotide exchange factor B
chr3_-_151176497 0.38 ENST00000282466.3
immunoglobulin superfamily, member 10
chr15_+_44119159 0.38 ENST00000263795.6
ENST00000381246.2
ENST00000452115.1
WD repeat domain 76
chr17_+_37894570 0.38 ENST00000394211.3
growth factor receptor-bound protein 7
chr12_+_56324756 0.37 ENST00000331886.5
ENST00000555090.1
diacylglycerol kinase, alpha 80kDa
chr2_+_102927962 0.37 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr12_-_54071181 0.37 ENST00000338662.5
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr13_-_41345277 0.37 ENST00000323563.6
mitochondrial ribosomal protein S31
chr1_+_156024525 0.36 ENST00000368305.4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr4_-_46996424 0.36 ENST00000264318.3
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr15_-_64386120 0.36 ENST00000300030.3
family with sequence similarity 96, member A
chr2_+_87769459 0.36 ENST00000414030.1
ENST00000437561.1
long intergenic non-protein coding RNA 152
chrX_-_52683950 0.35 ENST00000298181.5
synovial sarcoma, X breakpoint 7
chr3_-_123168551 0.35 ENST00000462833.1
adenylate cyclase 5
chr9_+_79792410 0.35 ENST00000357409.5
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr7_+_114562616 0.34 ENST00000448022.1
MyoD family inhibitor domain containing
chr2_-_86790472 0.34 ENST00000409727.1
charged multivesicular body protein 3
chr8_-_120868078 0.34 ENST00000313655.4
DNA replication and sister chromatid cohesion 1
chr6_+_24357131 0.33 ENST00000274766.1
kidney associated antigen 1
chr14_+_36295638 0.32 ENST00000543183.1
breast cancer metastasis-suppressor 1-like
chr17_+_39975455 0.32 ENST00000455106.1
FK506 binding protein 10, 65 kDa
chr1_+_25598872 0.32 ENST00000328664.4
Rh blood group, D antigen
chr6_-_84937314 0.32 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr11_-_108369101 0.31 ENST00000323468.5
KDEL (Lys-Asp-Glu-Leu) containing 2
chr14_-_67878917 0.31 ENST00000216446.4
pleckstrin 2
chr7_+_114562909 0.31 ENST00000423503.1
ENST00000427207.1
MyoD family inhibitor domain containing
chr17_+_75401152 0.31 ENST00000585930.1
septin 9
chrX_+_52240504 0.30 ENST00000399805.2
X antigen family, member 1B
chrX_-_7895755 0.30 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr1_-_17307173 0.29 ENST00000438542.1
ENST00000375535.3
microfibrillar-associated protein 2
chr1_+_150245177 0.29 ENST00000369098.3
chromosome 1 open reading frame 54
chr11_+_17298255 0.29 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
nucleobindin 2
chr21_+_39644305 0.29 ENST00000398930.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr8_-_7243080 0.28 ENST00000400156.4
zinc finger protein 705G
chr10_-_104178857 0.28 ENST00000020673.5
pleckstrin and Sec7 domain containing
chr10_-_120925054 0.28 ENST00000419372.1
ENST00000369131.4
ENST00000330036.6
ENST00000355697.2
sideroflexin 4
chr17_+_39975544 0.28 ENST00000544340.1
FK506 binding protein 10, 65 kDa
chr4_-_84406218 0.27 ENST00000515303.1
family with sequence similarity 175, member A
chr3_-_107596910 0.27 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
long intergenic non-protein coding RNA 635
chr4_-_129209944 0.27 ENST00000520121.1
progesterone receptor membrane component 2
chr4_+_25378912 0.27 ENST00000510092.1
ENST00000505991.1
anaphase promoting complex subunit 4
chr2_-_105882585 0.27 ENST00000595531.1
LOC644617 protein; Uncharacterized protein
chr2_-_86790593 0.27 ENST00000263856.4
ENST00000409225.2
charged multivesicular body protein 3
chr3_+_14989186 0.27 ENST00000435454.1
ENST00000323373.6
nuclear receptor subfamily 2, group C, member 2
chr22_-_36877629 0.26 ENST00000416967.1
thioredoxin 2
chr14_+_24899141 0.26 ENST00000556842.1
ENST00000553935.1
KH and NYN domain containing
chr16_+_103816 0.26 ENST00000383018.3
ENST00000417493.1
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr2_-_215674374 0.26 ENST00000449967.2
ENST00000421162.1
ENST00000260947.4
BRCA1 associated RING domain 1
chr16_+_11439286 0.26 ENST00000312499.5
ENST00000576027.1
RecQ mediated genome instability 2
chr11_+_17298297 0.26 ENST00000529010.1
nucleobindin 2
chr17_+_48503603 0.26 ENST00000502667.1
acyl-CoA synthetase family member 2
chr14_+_36295504 0.25 ENST00000216807.7
breast cancer metastasis-suppressor 1-like
chr15_-_60884706 0.25 ENST00000449337.2
RAR-related orphan receptor A
chr7_-_140714739 0.25 ENST00000467334.1
ENST00000324787.5
mitochondrial ribosomal protein S33
chr5_+_172483347 0.25 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREB3 regulatory factor
chr11_+_118868830 0.25 ENST00000334418.1
coiled-coil domain containing 84
chr14_+_55595762 0.24 ENST00000254301.9
lectin, galactoside-binding, soluble, 3
chrX_+_130192318 0.24 ENST00000370922.1
Rho GTPase activating protein 36
chr17_+_48503519 0.24 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
acyl-CoA synthetase family member 2
chr14_-_55658252 0.23 ENST00000395425.2
discs, large (Drosophila) homolog-associated protein 5
chr15_+_64428529 0.23 ENST00000560861.1
sorting nexin 1
chr7_+_856246 0.23 ENST00000389574.3
ENST00000457378.2
ENST00000452783.2
ENST00000435699.1
ENST00000440380.1
ENST00000439679.1
ENST00000424128.1
Sad1 and UNC84 domain containing 1
chr3_+_44803209 0.23 ENST00000326047.4
kinesin family member 15
chr10_-_74385876 0.23 ENST00000398761.4
mitochondrial calcium uptake 1
chr4_-_140223670 0.22 ENST00000394228.1
ENST00000539387.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr1_+_17248418 0.22 ENST00000375541.5
ciliary rootlet coiled-coil, rootletin
chr2_-_152589670 0.22 ENST00000604864.1
ENST00000603639.1
nebulin
chr22_+_42086547 0.22 ENST00000402966.1
chromosome 22 open reading frame 46
chr6_-_30899924 0.22 ENST00000359086.3
surfactant associated 2
chr1_+_150245099 0.21 ENST00000369099.3
chromosome 1 open reading frame 54
chr3_-_57113314 0.21 ENST00000338458.4
ENST00000468727.1
Rho guanine nucleotide exchange factor (GEF) 3
chr8_+_67687413 0.21 ENST00000521960.1
ENST00000522398.1
ENST00000522629.1
ENST00000520976.1
ENST00000396596.1
serum/glucocorticoid regulated kinase family, member 3
chr6_-_143832793 0.21 ENST00000438118.2
fucosidase, alpha-L- 2, plasma
chr18_+_5238055 0.21 ENST00000582363.1
ENST00000582008.1
ENST00000580082.1
long intergenic non-protein coding RNA 667
chr14_-_77737543 0.21 ENST00000298352.4
neuroglobin
chr2_-_20251744 0.20 ENST00000175091.4
lysosomal protein transmembrane 4 alpha
chr3_+_69985792 0.20 ENST00000531774.1
microphthalmia-associated transcription factor
chr19_+_4402659 0.20 ENST00000301280.5
ENST00000585854.1
chromatin assembly factor 1, subunit A (p150)
chr4_+_25378826 0.20 ENST00000315368.3
anaphase promoting complex subunit 4
chr10_-_12238071 0.20 ENST00000491614.1
ENST00000537776.1
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr2_-_55844720 0.20 ENST00000345102.5
ENST00000272313.5
ENST00000407823.3
SMEK homolog 2, suppressor of mek1 (Dictyostelium)
chr9_-_123639600 0.20 ENST00000373896.3
PHD finger protein 19
chr1_-_155214475 0.20 ENST00000428024.3
glucosidase, beta, acid
chrX_-_130037198 0.20 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ecto-NOX disulfide-thiol exchanger 2
chr10_-_74385811 0.20 ENST00000603011.1
ENST00000401998.3
ENST00000361114.5
ENST00000604238.1
mitochondrial calcium uptake 1
chr12_+_110338323 0.20 ENST00000312777.5
ENST00000536408.2
trichoplein, keratin filament binding
chr4_-_140223614 0.19 ENST00000394223.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_-_49864746 0.19 ENST00000598810.1
TEA domain family member 2
chrX_-_153707545 0.19 ENST00000357360.4
L antigen family, member 3
chr10_-_17659234 0.19 ENST00000466335.1
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr12_+_111843749 0.19 ENST00000341259.2
SH2B adaptor protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0100009 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.6 1.7 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.5 1.9 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.5 2.3 GO:0060023 soft palate development(GO:0060023)
0.3 1.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 1.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.3 0.9 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 2.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.9 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 0.6 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 0.6 GO:0007412 axon target recognition(GO:0007412) regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 1.5 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2 1.0 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 0.6 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.4 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.4 GO:1990918 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 1.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.6 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.8 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 1.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) phospholipid homeostasis(GO:0055091)
0.1 1.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.3 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.5 GO:1904044 response to aldosterone(GO:1904044)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.0 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 0.4 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.2 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.2 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.2 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.0 0.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.6 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.4 GO:2001023 regulation of response to drug(GO:2001023)
0.0 1.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:0021523 somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.4 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0071033 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0034398 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826) protein K6-linked ubiquitination(GO:0085020)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.9 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:2001191 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932) chondroblast differentiation(GO:0060591)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.5 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.2 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.9 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.1 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.8 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.6 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0071681 endothelial cell-cell adhesion(GO:0071603) response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.5 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.1 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.3 GO:0015695 organic cation transport(GO:0015695)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3 4.2 GO:0042555 MCM complex(GO:0042555)
0.2 0.9 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 1.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 0.7 GO:1990423 RZZ complex(GO:1990423)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 1.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 3.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 1.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0017129 triglyceride binding(GO:0017129)
0.3 1.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 3.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 0.5 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.2 0.7 GO:0003896 DNA primase activity(GO:0003896)
0.1 1.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.6 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.5 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.6 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.3 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 1.6 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 2.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 1.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 4.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.8 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0004040 amidase activity(GO:0004040)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation