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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for E2F8

Z-value: 0.86

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Transcription factors associated with E2F8

Gene Symbol Gene ID Gene Info
E2F8
ENSG00000129173.8 E2F transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F8hg19_v2_chr11_-_19263145_192631760.654.2e-04Click!

Activity profile of E2F8 motif

Sorted Z-values of E2F8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_131762105 2.88 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr9_-_74675521 2.34 ENST00000377024.3
C9orf57
chromosome 9 open reading frame 57
chr18_+_72922710 2.26 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr7_-_21985489 1.43 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L
cell division cycle associated 7-like
chr7_-_21985656 1.41 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr2_+_24346324 1.38 ENST00000407625.1
ENST00000420135.2
FAM228B
family with sequence similarity 228, member B
chr18_+_59992527 1.22 ENST00000586569.1
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr14_-_74551096 1.13 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr8_-_81083731 1.08 ENST00000379096.5
TPD52
tumor protein D52
chr22_+_35796056 1.04 ENST00000216122.4
MCM5
minichromosome maintenance complex component 5
chr11_-_19263145 1.04 ENST00000532666.1
ENST00000527884.1
E2F8
E2F transcription factor 8
chr2_-_177502659 1.03 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr2_-_58468437 1.02 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chr22_+_35796108 1.01 ENST00000382011.5
ENST00000416905.1
MCM5
minichromosome maintenance complex component 5
chr10_+_35416090 0.98 ENST00000354759.3
CREM
cAMP responsive element modulator
chr2_+_148778570 0.98 ENST00000407073.1
MBD5
methyl-CpG binding domain protein 5
chr11_+_47236489 0.96 ENST00000256996.4
ENST00000378603.3
ENST00000378600.3
ENST00000378601.3
DDB2
damage-specific DNA binding protein 2, 48kDa
chr1_+_197871854 0.94 ENST00000436652.1
C1orf53
chromosome 1 open reading frame 53
chr6_-_2962331 0.93 ENST00000380524.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr17_+_56769924 0.93 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr1_+_158979792 0.91 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr11_-_66445219 0.90 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B
RNA binding motif protein 4B
chr11_-_89224508 0.90 ENST00000525196.1
NOX4
NADPH oxidase 4
chr22_+_19467261 0.89 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45
cell division cycle 45
chr12_+_124155652 0.86 ENST00000426174.2
ENST00000303372.5
TCTN2
tectonic family member 2
chr12_-_6772303 0.86 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4
inhibitor of growth family, member 4
chr7_-_56119238 0.83 ENST00000275605.3
ENST00000395471.3
PSPH
phosphoserine phosphatase
chr18_+_59992514 0.83 ENST00000269485.7
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr12_-_15942503 0.83 ENST00000281172.5
EPS8
epidermal growth factor receptor pathway substrate 8
chr8_+_29952914 0.83 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr12_+_123011776 0.83 ENST00000450485.2
ENST00000333479.7
KNTC1
kinetochore associated 1
chr3_+_127317066 0.81 ENST00000265056.7
MCM2
minichromosome maintenance complex component 2
chr12_-_15942309 0.80 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr1_+_70876926 0.76 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr16_-_67185117 0.76 ENST00000449549.3
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr14_-_74551172 0.76 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chrX_+_10031499 0.75 ENST00000454666.1
WWC3
WWC family member 3
chr2_-_136633940 0.74 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr11_+_9595180 0.74 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr6_-_111804905 0.72 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr3_+_122296443 0.70 ENST00000464300.2
PARP15
poly (ADP-ribose) polymerase family, member 15
chr11_+_47586982 0.69 ENST00000426530.2
ENST00000534775.1
PTPMT1
protein tyrosine phosphatase, mitochondrial 1
chrX_-_54522558 0.69 ENST00000375135.3
FGD1
FYVE, RhoGEF and PH domain containing 1
chr13_+_21277482 0.68 ENST00000304920.3
IL17D
interleukin 17D
chr12_+_107168418 0.68 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr4_+_108910870 0.68 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
HADH
hydroxyacyl-CoA dehydrogenase
chrX_-_119695279 0.67 ENST00000336592.6
CUL4B
cullin 4B
chr12_-_57146095 0.67 ENST00000550770.1
ENST00000338193.6
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr8_+_118533049 0.66 ENST00000522839.1
MED30
mediator complex subunit 30
chr11_-_19262486 0.65 ENST00000250024.4
E2F8
E2F transcription factor 8
chr10_-_95360983 0.65 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr12_+_3069037 0.64 ENST00000397122.2
TEAD4
TEA domain family member 4
chr8_+_29953163 0.64 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr2_+_16080659 0.64 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr11_+_47587129 0.64 ENST00000326656.8
ENST00000326674.9
PTPMT1
protein tyrosine phosphatase, mitochondrial 1
chr10_+_35416223 0.63 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr8_+_118532937 0.63 ENST00000297347.3
MED30
mediator complex subunit 30
chr8_-_92053212 0.62 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr16_+_56995854 0.62 ENST00000566128.1
CETP
cholesteryl ester transfer protein, plasma
chr12_-_102455846 0.61 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr7_+_26331541 0.61 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr12_+_56661461 0.60 ENST00000546544.1
ENST00000553234.1
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr17_+_66243715 0.60 ENST00000359904.3
AMZ2
archaelysin family metallopeptidase 2
chr6_-_32157947 0.59 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr9_+_130374537 0.59 ENST00000373302.3
ENST00000373299.1
STXBP1
syntaxin binding protein 1
chr1_+_197871740 0.57 ENST00000367393.3
C1orf53
chromosome 1 open reading frame 53
chr7_+_100136811 0.56 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chrX_-_135338503 0.55 ENST00000370663.5
MAP7D3
MAP7 domain containing 3
chr1_-_6295975 0.54 ENST00000343813.5
ENST00000362035.3
ICMT
isoprenylcysteine carboxyl methyltransferase
chr7_-_56118981 0.54 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
PSPH
phosphoserine phosphatase
chrX_+_55026763 0.53 ENST00000374987.3
APEX2
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr12_-_102455902 0.53 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr2_+_10262857 0.53 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr19_-_51845378 0.52 ENST00000335624.4
VSIG10L
V-set and immunoglobulin domain containing 10 like
chrX_-_10588459 0.52 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr5_+_31532373 0.52 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22
chromosome 5 open reading frame 22
chr12_+_56521840 0.52 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr1_+_70876891 0.52 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr16_+_56995762 0.51 ENST00000200676.3
ENST00000379780.2
CETP
cholesteryl ester transfer protein, plasma
chr1_+_97187318 0.50 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chrX_-_129299847 0.50 ENST00000319908.3
ENST00000287295.3
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr1_+_201798269 0.50 ENST00000361565.4
IPO9
importin 9
chrX_-_10588595 0.49 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr15_-_57025759 0.49 ENST00000267807.7
ZNF280D
zinc finger protein 280D
chr7_-_56119156 0.49 ENST00000421312.1
ENST00000416592.1
PSPH
phosphoserine phosphatase
chr2_-_70780572 0.48 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr17_-_9479128 0.47 ENST00000574431.1
STX8
syntaxin 8
chr12_-_71003568 0.47 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr9_+_131445928 0.47 ENST00000372692.4
SET
SET nuclear oncogene
chr17_-_60005365 0.45 ENST00000444766.3
INTS2
integrator complex subunit 2
chr4_-_57844989 0.45 ENST00000264230.4
NOA1
nitric oxide associated 1
chr1_+_156024552 0.45 ENST00000368304.5
ENST00000368302.3
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr17_-_46623441 0.45 ENST00000330070.4
HOXB2
homeobox B2
chr17_-_59940830 0.44 ENST00000259008.2
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr9_+_99690592 0.44 ENST00000354649.3
NUTM2G
NUT family member 2G
chr2_-_130956006 0.43 ENST00000312988.7
TUBA3E
tubulin, alpha 3e
chr12_+_56324933 0.43 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr10_+_115312766 0.42 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr16_-_18812746 0.42 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ARL6IP1
RP11-1035H13.3
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr4_-_174254823 0.41 ENST00000438704.2
HMGB2
high mobility group box 2
chr17_-_30668887 0.41 ENST00000581747.1
ENST00000583334.1
ENST00000580558.1
C17orf75
chromosome 17 open reading frame 75
chr22_-_19974616 0.41 ENST00000344269.3
ENST00000401994.1
ENST00000406522.1
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr8_+_48873479 0.41 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr14_+_105992906 0.40 ENST00000392519.2
TMEM121
transmembrane protein 121
chr4_-_39367949 0.39 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chr20_+_31595406 0.39 ENST00000170150.3
BPIFB2
BPI fold containing family B, member 2
chr6_+_127588020 0.39 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146
ring finger protein 146
chr8_+_48873453 0.39 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr15_-_64385981 0.38 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr12_+_107168342 0.38 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr3_-_151176497 0.38 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr15_+_44119159 0.38 ENST00000263795.6
ENST00000381246.2
ENST00000452115.1
WDR76
WD repeat domain 76
chr17_+_37894570 0.38 ENST00000394211.3
GRB7
growth factor receptor-bound protein 7
chr12_+_56324756 0.37 ENST00000331886.5
ENST00000555090.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr2_+_102927962 0.37 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr12_-_54071181 0.37 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr13_-_41345277 0.37 ENST00000323563.6
MRPS31
mitochondrial ribosomal protein S31
chr1_+_156024525 0.36 ENST00000368305.4
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr4_-_46996424 0.36 ENST00000264318.3
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr15_-_64386120 0.36 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr2_+_87769459 0.36 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chrX_-_52683950 0.35 ENST00000298181.5
SSX7
synovial sarcoma, X breakpoint 7
chr3_-_123168551 0.35 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr9_+_79792410 0.35 ENST00000357409.5
VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr7_+_114562616 0.34 ENST00000448022.1
MDFIC
MyoD family inhibitor domain containing
chr2_-_86790472 0.34 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr8_-_120868078 0.34 ENST00000313655.4
DSCC1
DNA replication and sister chromatid cohesion 1
chr6_+_24357131 0.33 ENST00000274766.1
KAAG1
kidney associated antigen 1
chr14_+_36295638 0.32 ENST00000543183.1
BRMS1L
breast cancer metastasis-suppressor 1-like
chr17_+_39975455 0.32 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr1_+_25598872 0.32 ENST00000328664.4
RHD
Rh blood group, D antigen
chr6_-_84937314 0.32 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr11_-_108369101 0.31 ENST00000323468.5
KDELC2
KDEL (Lys-Asp-Glu-Leu) containing 2
chr14_-_67878917 0.31 ENST00000216446.4
PLEK2
pleckstrin 2
chr7_+_114562909 0.31 ENST00000423503.1
ENST00000427207.1
MDFIC
MyoD family inhibitor domain containing
chr17_+_75401152 0.31 ENST00000585930.1
SEPT9
septin 9
chrX_+_52240504 0.30 ENST00000399805.2
XAGE1B
X antigen family, member 1B
chrX_-_7895755 0.30 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
PNPLA4
patatin-like phospholipase domain containing 4
chr1_-_17307173 0.29 ENST00000438542.1
ENST00000375535.3
MFAP2
microfibrillar-associated protein 2
chr1_+_150245177 0.29 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr11_+_17298255 0.29 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
NUCB2
nucleobindin 2
chr21_+_39644305 0.29 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr8_-_7243080 0.28 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr10_-_104178857 0.28 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr10_-_120925054 0.28 ENST00000419372.1
ENST00000369131.4
ENST00000330036.6
ENST00000355697.2
SFXN4
sideroflexin 4
chr17_+_39975544 0.28 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr4_-_84406218 0.27 ENST00000515303.1
FAM175A
family with sequence similarity 175, member A
chr3_-_107596910 0.27 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
LINC00635
long intergenic non-protein coding RNA 635
chr4_-_129209944 0.27 ENST00000520121.1
PGRMC2
progesterone receptor membrane component 2
chr4_+_25378912 0.27 ENST00000510092.1
ENST00000505991.1
ANAPC4
anaphase promoting complex subunit 4
chr2_-_105882585 0.27 ENST00000595531.1
AC012360.2
LOC644617 protein; Uncharacterized protein
chr2_-_86790593 0.27 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr3_+_14989186 0.27 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr22_-_36877629 0.26 ENST00000416967.1
TXN2
thioredoxin 2
chr14_+_24899141 0.26 ENST00000556842.1
ENST00000553935.1
KHNYN
KH and NYN domain containing
chr16_+_103816 0.26 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr2_-_215674374 0.26 ENST00000449967.2
ENST00000421162.1
ENST00000260947.4
BARD1
BRCA1 associated RING domain 1
chr16_+_11439286 0.26 ENST00000312499.5
ENST00000576027.1
RMI2
RecQ mediated genome instability 2
chr11_+_17298297 0.26 ENST00000529010.1
NUCB2
nucleobindin 2
chr17_+_48503603 0.26 ENST00000502667.1
ACSF2
acyl-CoA synthetase family member 2
chr14_+_36295504 0.25 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr15_-_60884706 0.25 ENST00000449337.2
RORA
RAR-related orphan receptor A
chr7_-_140714739 0.25 ENST00000467334.1
ENST00000324787.5
MRPS33
mitochondrial ribosomal protein S33
chr5_+_172483347 0.25 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr11_+_118868830 0.25 ENST00000334418.1
CCDC84
coiled-coil domain containing 84
chr14_+_55595762 0.24 ENST00000254301.9
LGALS3
lectin, galactoside-binding, soluble, 3
chrX_+_130192318 0.24 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr17_+_48503519 0.24 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
ACSF2
acyl-CoA synthetase family member 2
chr14_-_55658252 0.23 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr15_+_64428529 0.23 ENST00000560861.1
SNX1
sorting nexin 1
chr7_+_856246 0.23 ENST00000389574.3
ENST00000457378.2
ENST00000452783.2
ENST00000435699.1
ENST00000440380.1
ENST00000439679.1
ENST00000424128.1
SUN1
Sad1 and UNC84 domain containing 1
chr3_+_44803209 0.23 ENST00000326047.4
KIF15
kinesin family member 15
chr10_-_74385876 0.23 ENST00000398761.4
MICU1
mitochondrial calcium uptake 1
chr4_-_140223670 0.22 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr1_+_17248418 0.22 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chr2_-_152589670 0.22 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr22_+_42086547 0.22 ENST00000402966.1
C22orf46
chromosome 22 open reading frame 46
chr6_-_30899924 0.22 ENST00000359086.3
SFTA2
surfactant associated 2
chr1_+_150245099 0.21 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr3_-_57113314 0.21 ENST00000338458.4
ENST00000468727.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr8_+_67687413 0.21 ENST00000521960.1
ENST00000522398.1
ENST00000522629.1
ENST00000520976.1
ENST00000396596.1
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr6_-_143832793 0.21 ENST00000438118.2
FUCA2
fucosidase, alpha-L- 2, plasma
chr18_+_5238055 0.21 ENST00000582363.1
ENST00000582008.1
ENST00000580082.1
LINC00667
long intergenic non-protein coding RNA 667
chr14_-_77737543 0.21 ENST00000298352.4
NGB
neuroglobin
chr2_-_20251744 0.20 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr3_+_69985792 0.20 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr19_+_4402659 0.20 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr4_+_25378826 0.20 ENST00000315368.3
ANAPC4
anaphase promoting complex subunit 4
chr10_-_12238071 0.20 ENST00000491614.1
ENST00000537776.1
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr2_-_55844720 0.20 ENST00000345102.5
ENST00000272313.5
ENST00000407823.3
SMEK2
SMEK homolog 2, suppressor of mek1 (Dictyostelium)
chr9_-_123639600 0.20 ENST00000373896.3
PHF19
PHD finger protein 19
chr1_-_155214475 0.20 ENST00000428024.3
GBA
glucosidase, beta, acid
chrX_-_130037198 0.20 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr10_-_74385811 0.20 ENST00000603011.1
ENST00000401998.3
ENST00000361114.5
ENST00000604238.1
MICU1
mitochondrial calcium uptake 1
chr12_+_110338323 0.20 ENST00000312777.5
ENST00000536408.2
TCHP
trichoplein, keratin filament binding
chr4_-_140223614 0.19 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_-_49864746 0.19 ENST00000598810.1
TEAD2
TEA domain family member 2
chrX_-_153707545 0.19 ENST00000357360.4
LAGE3
L antigen family, member 3
chr10_-_17659234 0.19 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr12_+_111843749 0.19 ENST00000341259.2
SH2B3
SH2B adaptor protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0100009 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.6 1.7 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.5 1.9 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.5 2.3 GO:0060023 soft palate development(GO:0060023)
0.3 1.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 1.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.3 0.9 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 2.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.9 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 0.6 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 0.6 GO:0007412 axon target recognition(GO:0007412) regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 1.5 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2 1.0 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 0.6 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.4 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.4 GO:1990918 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 1.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.6 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.8 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 1.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) phospholipid homeostasis(GO:0055091)
0.1 1.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.3 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.5 GO:1904044 response to aldosterone(GO:1904044)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.0 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 0.4 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.2 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.2 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.2 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.0 0.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.6 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.4 GO:2001023 regulation of response to drug(GO:2001023)
0.0 1.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:0021523 somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.4 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0071033 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0034398 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826) protein K6-linked ubiquitination(GO:0085020)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.9 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:2001191 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932) chondroblast differentiation(GO:0060591)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.5 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.2 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.9 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.1 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.8 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.6 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0071681 endothelial cell-cell adhesion(GO:0071603) response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.5 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.1 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.3 GO:0015695 organic cation transport(GO:0015695)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3 4.2 GO:0042555 MCM complex(GO:0042555)
0.2 0.9 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 1.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 0.7 GO:1990423 RZZ complex(GO:1990423)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 1.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 3.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 1.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0017129 triglyceride binding(GO:0017129)
0.3 1.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 3.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 0.5 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.2 0.7 GO:0003896 DNA primase activity(GO:0003896)
0.1 1.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.6 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.5 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.6 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.3 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 1.6 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 2.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 1.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 4.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.8 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0004040 amidase activity(GO:0004040)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation