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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for EMX2

Z-value: 1.01

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Transcription factors associated with EMX2

Gene Symbol Gene ID Gene Info
EMX2
ENSG00000170370.10 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX2hg19_v2_chr10_+_119301928_1193019550.281.7e-01Click!

Activity profile of EMX2 motif

Sorted Z-values of EMX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_41540160 4.79 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr4_-_101439242 4.20 ENST00000296420.4
EMCN
endomucin
chr1_+_84609944 3.97 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_-_76072719 3.40 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr4_-_101439148 3.26 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
EMCN
endomucin
chr2_-_99279928 2.79 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr9_-_47314222 2.73 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
AL953854.2
chr5_-_111093167 2.73 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr11_-_63376013 2.63 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr4_-_186877806 2.61 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chrX_+_10031499 2.50 ENST00000454666.1
WWC3
WWC family member 3
chr4_-_186877502 2.35 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr8_-_81083890 2.33 ENST00000518937.1
TPD52
tumor protein D52
chr5_-_111093081 2.19 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr9_+_71986182 2.05 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr21_-_31869451 1.96 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr5_-_111092930 1.95 ENST00000257435.7
NREP
neuronal regeneration related protein
chr17_-_67138015 1.95 ENST00000284425.2
ENST00000590645.1
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr8_-_93029865 1.95 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_120687335 1.91 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr9_+_75766763 1.88 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr1_+_78470530 1.84 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr3_-_141719195 1.81 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_+_13141097 1.81 ENST00000411542.1
AC011288.2
AC011288.2
chr8_+_98900132 1.74 ENST00000520016.1
MATN2
matrilin 2
chr5_-_111312622 1.70 ENST00000395634.3
NREP
neuronal regeneration related protein
chrX_+_77166172 1.68 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr12_+_60083118 1.66 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr5_-_55412774 1.60 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr12_-_10007448 1.54 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr9_+_71944241 1.52 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr3_-_122512619 1.50 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr6_-_110501200 1.50 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WASF1
WAS protein family, member 1
chr1_+_78383813 1.47 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr12_-_25055177 1.42 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr17_-_295730 1.42 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr3_+_132316081 1.34 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr12_+_10365404 1.33 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr11_-_124981475 1.31 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218
transmembrane protein 218
chr6_+_28092338 1.25 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr4_-_138453606 1.24 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr11_+_92085262 1.22 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr1_-_160924589 1.20 ENST00000368029.3
ITLN2
intelectin 2
chr1_-_45452240 1.19 ENST00000372183.3
ENST00000372182.4
ENST00000360403.2
EIF2B3
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
chr3_-_141747950 1.16 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr6_+_72926145 1.15 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr5_-_9630463 1.13 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr12_+_80603233 1.06 ENST00000547103.1
ENST00000458043.2
OTOGL
otogelin-like
chr5_-_140013275 1.06 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr15_-_57025759 1.04 ENST00000267807.7
ZNF280D
zinc finger protein 280D
chr21_+_17792672 1.03 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_123201337 1.00 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr7_+_115862858 1.00 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr3_-_58523010 0.99 ENST00000459701.2
ENST00000302819.5
ACOX2
acyl-CoA oxidase 2, branched chain
chr1_+_28764653 0.94 ENST00000373836.3
PHACTR4
phosphatase and actin regulator 4
chr4_-_25865159 0.93 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr8_+_39770803 0.93 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr6_-_26235206 0.92 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr6_+_27833034 0.90 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr12_+_29302119 0.89 ENST00000536681.3
FAR2
fatty acyl CoA reductase 2
chr19_+_50016610 0.88 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr9_-_5833027 0.87 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr15_-_20193370 0.85 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr21_+_17553910 0.85 ENST00000428669.2
LINC00478
long intergenic non-protein coding RNA 478
chrX_+_55744228 0.77 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr3_+_113616317 0.76 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C
chr4_-_72649763 0.76 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr7_+_107224364 0.75 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr12_-_68696652 0.75 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr1_+_248185250 0.74 ENST00000355281.1
OR2L5
olfactory receptor, family 2, subfamily L, member 5
chr19_-_58864848 0.73 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr14_+_102276132 0.73 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chrX_+_55744166 0.71 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr17_+_5031687 0.71 ENST00000250066.6
ENST00000304328.5
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr22_+_40440804 0.71 ENST00000441751.1
ENST00000301923.9
TNRC6B
trinucleotide repeat containing 6B
chr12_-_123187890 0.68 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr12_+_101988627 0.68 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr18_+_20513278 0.66 ENST00000327155.5
RBBP8
retinoblastoma binding protein 8
chr9_-_21202204 0.66 ENST00000239347.3
IFNA7
interferon, alpha 7
chr12_+_125549925 0.65 ENST00000316519.6
AACS
acetoacetyl-CoA synthetase
chr5_-_88119580 0.64 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr4_-_100356551 0.64 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr13_+_103459704 0.63 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr22_-_32860427 0.62 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr6_+_72922505 0.60 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_117544366 0.59 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr12_+_101988774 0.58 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr8_+_70404996 0.58 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr18_+_29769978 0.58 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr22_+_45725524 0.58 ENST00000405548.3
FAM118A
family with sequence similarity 118, member A
chr2_+_44001172 0.58 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
DYNC2LI1
dynein, cytoplasmic 2, light intermediate chain 1
chr6_+_26251835 0.57 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr15_+_58702742 0.56 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr5_-_111754948 0.55 ENST00000261486.5
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr3_+_148508845 0.55 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr19_-_44388116 0.54 ENST00000587539.1
ZNF404
zinc finger protein 404
chr8_+_62747349 0.54 ENST00000517953.1
ENST00000520097.1
ENST00000519766.1
RP11-705O24.1
RP11-705O24.1
chr10_+_51187938 0.54 ENST00000311663.5
FAM21D
family with sequence similarity 21, member D
chr16_+_22524844 0.54 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr5_+_118812237 0.53 ENST00000513628.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr6_+_116421976 0.53 ENST00000319550.4
ENST00000419791.1
NT5DC1
5'-nucleotidase domain containing 1
chr4_-_100140331 0.53 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr6_+_72922590 0.53 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr12_-_58220078 0.53 ENST00000549039.1
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr16_+_28763108 0.53 ENST00000357796.3
ENST00000550983.1
NPIPB9
nuclear pore complex interacting protein family, member B9
chr5_+_118812294 0.52 ENST00000509514.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr12_+_125549973 0.52 ENST00000536752.1
ENST00000261686.6
AACS
acetoacetyl-CoA synthetase
chr12_-_10978957 0.52 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr19_-_37697976 0.52 ENST00000588873.1
CTC-454I21.3
Uncharacterized protein; Zinc finger protein 585B
chr11_-_104916034 0.52 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr2_+_28718921 0.51 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
PLB1
phospholipase B1
chr13_-_107214291 0.51 ENST00000375926.1
ARGLU1
arginine and glutamate rich 1
chr5_-_94417339 0.51 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr2_-_62733476 0.50 ENST00000335390.5
TMEM17
transmembrane protein 17
chr8_-_144660771 0.50 ENST00000449291.2
NAPRT1
nicotinate phosphoribosyltransferase domain containing 1
chr4_-_100356291 0.48 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr8_+_67687413 0.48 ENST00000521960.1
ENST00000522398.1
ENST00000522629.1
ENST00000520976.1
ENST00000396596.1
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr12_+_59989918 0.48 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr2_+_48796120 0.48 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr11_+_74303575 0.47 ENST00000263681.2
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr8_+_110552831 0.47 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr11_+_66276550 0.47 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr22_+_24407642 0.47 ENST00000454754.1
ENST00000263119.5
CABIN1
calcineurin binding protein 1
chr19_+_58144529 0.46 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
ZNF211
zinc finger protein 211
chr3_+_158787041 0.46 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr12_-_8803128 0.46 ENST00000543467.1
MFAP5
microfibrillar associated protein 5
chr16_-_21436459 0.46 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr5_+_140514782 0.45 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr11_+_119019722 0.45 ENST00000307417.3
ABCG4
ATP-binding cassette, sub-family G (WHITE), member 4
chr16_+_18995249 0.45 ENST00000569532.1
ENST00000304381.5
TMC7
transmembrane channel-like 7
chr17_+_62461569 0.45 ENST00000603557.1
ENST00000605096.1
MILR1
mast cell immunoglobulin-like receptor 1
chrX_+_130192318 0.45 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr4_+_80584903 0.45 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr12_-_53171128 0.45 ENST00000332411.2
KRT76
keratin 76
chr19_-_51920952 0.44 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr16_+_28648975 0.44 ENST00000529716.1
NPIPB8
nuclear pore complex interacting protein family, member B8
chrX_+_47444613 0.44 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr2_-_179343226 0.44 ENST00000434643.2
FKBP7
FK506 binding protein 7
chr8_-_133687778 0.44 ENST00000518642.1
LRRC6
leucine rich repeat containing 6
chr12_-_53715328 0.44 ENST00000547757.1
ENST00000394384.3
ENST00000209873.4
AAAS
achalasia, adrenocortical insufficiency, alacrimia
chrX_+_135730297 0.43 ENST00000370629.2
CD40LG
CD40 ligand
chr1_-_19615744 0.43 ENST00000361640.4
AKR7A3
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr1_+_15668240 0.43 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr15_-_65426174 0.42 ENST00000204549.4
PDCD7
programmed cell death 7
chr8_-_101571933 0.42 ENST00000520311.1
ANKRD46
ankyrin repeat domain 46
chr16_-_28374829 0.42 ENST00000532254.1
NPIPB6
nuclear pore complex interacting protein family, member B6
chr8_-_121457608 0.42 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr9_+_125133315 0.42 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_+_66521936 0.42 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr5_-_137475071 0.42 ENST00000265191.2
NME5
NME/NM23 family member 5
chr17_-_34757039 0.41 ENST00000455054.2
ENST00000308078.7
TBC1D3H
TBC1D3C
TBC1 domain family, member 3H
TBC1 domain family, member 3C
chr16_+_15489603 0.41 ENST00000568766.1
ENST00000287594.7
RP11-1021N1.1
MPV17L
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr14_+_54863667 0.41 ENST00000335183.6
CDKN3
cyclin-dependent kinase inhibitor 3
chr12_-_112279694 0.41 ENST00000443596.1
ENST00000442119.1
MAPKAPK5-AS1
MAPKAPK5 antisense RNA 1
chr1_+_81771806 0.41 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr21_+_31768348 0.40 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr1_-_54405773 0.39 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr12_-_118797475 0.38 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chrX_+_135730373 0.37 ENST00000370628.2
CD40LG
CD40 ligand
chr16_-_21868978 0.37 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
NPIPB4
nuclear pore complex interacting protein family, member B4
chrX_+_154254960 0.37 ENST00000369498.3
FUNDC2
FUN14 domain containing 2
chr8_-_54755459 0.37 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr18_+_6729725 0.36 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr14_-_90420862 0.36 ENST00000556005.1
ENST00000555872.1
EFCAB11
EF-hand calcium binding domain 11
chr6_+_42018614 0.36 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr11_+_7110165 0.35 ENST00000306904.5
RBMXL2
RNA binding motif protein, X-linked-like 2
chr4_-_68411275 0.35 ENST00000273853.6
CENPC
centromere protein C
chr20_-_29978383 0.34 ENST00000339144.3
ENST00000376321.3
DEFB119
defensin, beta 119
chr5_+_147774275 0.34 ENST00000513826.1
FBXO38
F-box protein 38
chr17_-_42100474 0.34 ENST00000585950.1
ENST00000592127.1
ENST00000589334.1
TMEM101
transmembrane protein 101
chr12_-_71533055 0.34 ENST00000552128.1
TSPAN8
tetraspanin 8
chr6_+_110501621 0.33 ENST00000368930.1
ENST00000307731.1
CDC40
cell division cycle 40
chr11_-_59950486 0.33 ENST00000426738.2
ENST00000533023.1
ENST00000420732.2
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr3_-_20053741 0.33 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chr8_+_110552337 0.32 ENST00000337573.5
EBAG9
estrogen receptor binding site associated, antigen, 9
chr3_+_130745688 0.32 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11
NIMA-related kinase 11
chr11_-_59950622 0.32 ENST00000323961.3
ENST00000412309.2
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr16_-_29415350 0.32 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chr4_+_56212505 0.32 ENST00000505210.1
SRD5A3
steroid 5 alpha-reductase 3
chr20_+_33563206 0.31 ENST00000262873.7
MYH7B
myosin, heavy chain 7B, cardiac muscle, beta
chr8_+_26150628 0.31 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr7_+_1727755 0.31 ENST00000424383.2
ELFN1
extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr7_+_90338712 0.31 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr16_+_69599861 0.31 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_+_122709200 0.31 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr17_-_34503867 0.30 ENST00000589443.1
ENST00000454519.3
ENST00000586369.1
TBC1D3B
TBC1 domain family, member 3B
chr3_-_185538849 0.30 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr5_-_75919253 0.30 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr11_-_59950519 0.30 ENST00000528851.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr8_-_133687813 0.29 ENST00000250173.1
ENST00000519595.1
LRRC6
leucine rich repeat containing 6
chr9_-_99540328 0.29 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510
zinc finger protein 510
chr5_-_43557791 0.29 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
PAIP1
poly(A) binding protein interacting protein 1
chr1_-_139379 0.29 ENST00000423372.3
AL627309.1
Uncharacterized protein
chr4_+_174818390 0.29 ENST00000509968.1
ENST00000512263.1
RP11-161D15.1
RP11-161D15.1
chr7_+_138915102 0.29 ENST00000486663.1
UBN2
ubinuclein 2
chr5_-_86534822 0.28 ENST00000445770.2
AC008394.1
Uncharacterized protein
chr15_+_48009541 0.28 ENST00000536845.2
ENST00000558816.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr3_-_49466686 0.28 ENST00000273598.3
ENST00000436744.2
NICN1
nicolin 1
chr21_-_27423339 0.28 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr1_+_160709076 0.28 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.6 4.0 GO:0097338 response to clozapine(GO:0097338)
0.6 1.7 GO:0071284 cellular response to lead ion(GO:0071284)
0.4 1.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 0.9 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 2.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.3 1.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.3 1.1 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.3 2.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.4 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 0.9 GO:0036269 swimming behavior(GO:0036269)
0.2 0.9 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 2.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 1.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.2 0.7 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 1.5 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 0.6 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 1.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 1.2 GO:0034201 response to oleic acid(GO:0034201)
0.1 5.0 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.5 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 2.0 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.9 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 1.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 2.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.2 GO:0060559 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.1 1.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 1.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.7 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 2.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 2.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.8 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.4 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.7 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.5 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.8 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.8 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.8 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0035898 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.4 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835) negative regulation of activated T cell proliferation(GO:0046007)
0.0 1.9 GO:0008347 glial cell migration(GO:0008347)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 1.9 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.5 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 1.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 2.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.2 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 1.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 1.7 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 1.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.2 1.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 4.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 0.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.4 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 1.4 GO:0032982 myosin filament(GO:0032982)
0.0 4.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 1.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 6.3 GO:0030018 Z disc(GO:0030018)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 1.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 3.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0032767 copper-dependent protein binding(GO:0032767)
0.5 2.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.5 2.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3 0.9 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.3 2.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 1.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.3 0.8 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 1.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.2 1.0 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.2 1.4 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 4.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.9 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.9 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 1.1 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.2 5.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 0.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 1.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.5 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 0.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.5 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 2.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 1.3 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.2 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.3 GO:0031432 titin binding(GO:0031432)
0.1 1.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 1.3 GO:0019956 chemokine binding(GO:0019956)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0004520 endodeoxyribonuclease activity(GO:0004520)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID IL3 PATHWAY IL3-mediated signaling events
0.1 13.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 5.4 PID E2F PATHWAY E2F transcription factor network
0.0 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 4.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 2.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination