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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for EOMES

Z-value: 0.65

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Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
EOMES
ENSG00000163508.8 eomesodermin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EOMEShg19_v2_chr3_-_27764190_27764208-0.331.0e-01Click!

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_184943610 2.44 ENST00000367511.3
FAM129A
family with sequence similarity 129, member A
chr17_+_77020325 1.98 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr15_+_89182156 1.97 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr2_-_225907150 1.95 ENST00000258390.7
DOCK10
dedicator of cytokinesis 10
chr15_+_89182178 1.92 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89181974 1.53 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr3_-_64673668 1.47 ENST00000498707.1
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr17_+_77020224 1.38 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr16_+_86544113 1.10 ENST00000262426.4
FOXF1
forkhead box F1
chr7_+_55177416 1.03 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr17_+_80332153 0.95 ENST00000313135.2
UTS2R
urotensin 2 receptor
chr11_-_441964 0.94 ENST00000332826.6
ANO9
anoctamin 9
chr1_-_1149506 0.80 ENST00000379236.3
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr12_+_121570631 0.80 ENST00000546057.1
ENST00000377162.2
ENST00000328963.5
ENST00000535250.1
ENST00000541446.1
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr11_+_69455855 0.78 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr4_-_80994619 0.75 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr13_-_102068706 0.74 ENST00000251127.6
NALCN
sodium leak channel, non-selective
chr3_+_111805182 0.73 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
C3orf52
chromosome 3 open reading frame 52
chr11_+_35201826 0.70 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr8_-_90996837 0.66 ENST00000519426.1
ENST00000265433.3
NBN
nibrin
chr4_-_80994210 0.65 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr1_+_113217345 0.65 ENST00000357443.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr8_-_90996459 0.64 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr5_+_156693159 0.63 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr12_-_117318788 0.63 ENST00000550505.1
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr4_-_80994471 0.61 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr1_+_113217309 0.60 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_113217043 0.59 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr8_+_104383728 0.58 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr5_+_96212185 0.57 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr3_-_113775328 0.56 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407
KIAA1407
chr1_+_113217073 0.55 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr5_+_156693091 0.55 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr12_+_121647962 0.55 ENST00000542067.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr9_-_38069208 0.53 ENST00000377707.3
ENST00000377700.4
SHB
Src homology 2 domain containing adaptor protein B
chr10_+_104154229 0.52 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr2_-_163175133 0.51 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr8_-_9760839 0.51 ENST00000519461.1
ENST00000517675.1
LINC00599
long intergenic non-protein coding RNA 599
chr4_-_103997455 0.50 ENST00000362026.3
ENST00000503103.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr1_-_207095212 0.50 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr22_-_50970506 0.50 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr7_+_28452130 0.49 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr4_+_25235597 0.49 ENST00000264864.6
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr3_+_11196206 0.48 ENST00000431010.2
HRH1
histamine receptor H1
chr20_-_18038521 0.48 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chr5_+_52083730 0.47 ENST00000282588.6
ENST00000274311.2
ITGA1
PELO
integrin, alpha 1
pelota homolog (Drosophila)
chr5_+_96211643 0.47 ENST00000437043.3
ENST00000510373.1
ERAP2
endoplasmic reticulum aminopeptidase 2
chr19_-_49496557 0.47 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr8_+_81397876 0.44 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr22_-_50913371 0.42 ENST00000348911.6
ENST00000380817.3
ENST00000390679.3
SBF1
SET binding factor 1
chr11_-_66056596 0.42 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr11_+_93861993 0.41 ENST00000227638.3
ENST00000436171.2
PANX1
pannexin 1
chr16_-_67693846 0.41 ENST00000602850.1
ACD
adrenocortical dysplasia homolog (mouse)
chr22_-_18257178 0.40 ENST00000342111.5
BID
BH3 interacting domain death agonist
chr12_-_52779433 0.39 ENST00000257951.3
KRT84
keratin 84
chr22_+_31644388 0.39 ENST00000333611.4
ENST00000340552.4
LIMK2
LIM domain kinase 2
chr14_-_53162361 0.38 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr1_-_241520525 0.38 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chrX_+_140982452 0.37 ENST00000544766.1
MAGEC3
melanoma antigen family C, 3
chr21_-_47352477 0.37 ENST00000593412.1
PRED62
Uncharacterized protein
chr11_-_65686586 0.37 ENST00000438576.2
C11orf68
chromosome 11 open reading frame 68
chr1_+_37940153 0.37 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr1_+_162531294 0.36 ENST00000367926.4
ENST00000271469.3
UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1
chr8_+_31496809 0.36 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr4_-_76555657 0.36 ENST00000307465.4
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr11_+_33902189 0.35 ENST00000330381.2
AC132216.1
HCG1785179; PRO1787; Uncharacterized protein
chr5_+_125758865 0.35 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr14_-_64108125 0.35 ENST00000267522.3
WDR89
WD repeat domain 89
chr1_-_241520385 0.35 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr8_+_59465728 0.34 ENST00000260130.4
ENST00000422546.2
ENST00000447182.2
ENST00000413219.2
ENST00000424270.2
ENST00000523483.1
ENST00000520168.1
SDCBP
syndecan binding protein (syntenin)
chr8_+_144099896 0.34 ENST00000292494.6
ENST00000429120.2
LY6E
lymphocyte antigen 6 complex, locus E
chr5_+_125758813 0.34 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr3_+_133292574 0.33 ENST00000264993.3
CDV3
CDV3 homolog (mouse)
chr20_+_45523227 0.33 ENST00000327619.5
ENST00000357410.3
EYA2
eyes absent homolog 2 (Drosophila)
chr17_+_37784749 0.33 ENST00000394265.1
ENST00000394267.2
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr1_-_196577489 0.33 ENST00000609185.1
ENST00000451324.2
ENST00000367433.5
ENST00000367431.4
KCNT2
potassium channel, subfamily T, member 2
chr17_+_56270084 0.33 ENST00000225371.5
EPX
eosinophil peroxidase
chr4_+_8321882 0.32 ENST00000509453.1
ENST00000503186.1
RP11-774O3.2
RP11-774O3.1
RP11-774O3.2
RP11-774O3.1
chr8_+_144099914 0.32 ENST00000521699.1
ENST00000520531.1
ENST00000520466.1
ENST00000521003.1
ENST00000522528.1
ENST00000522971.1
ENST00000519611.1
ENST00000521182.1
ENST00000519546.1
ENST00000523847.1
ENST00000522024.1
LY6E
lymphocyte antigen 6 complex, locus E
chr2_+_201170703 0.32 ENST00000358677.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr6_+_34204642 0.32 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr14_-_51135036 0.32 ENST00000324679.4
SAV1
salvador homolog 1 (Drosophila)
chr4_-_74964904 0.31 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr22_+_38071615 0.31 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr16_-_90038866 0.31 ENST00000314994.3
CENPBD1
CENPB DNA-binding domains containing 1
chr17_-_27949911 0.31 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6
coronin 6
chr11_-_66056478 0.30 ENST00000431556.2
ENST00000528575.1
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr15_-_83953466 0.30 ENST00000345382.2
BNC1
basonuclin 1
chr17_+_79650962 0.30 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr16_+_30064444 0.30 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA
aldolase A, fructose-bisphosphate
chr6_+_45389893 0.30 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr16_-_66959429 0.29 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr15_-_56285742 0.29 ENST00000435532.3
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr1_-_93426998 0.29 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr17_-_74722536 0.29 ENST00000585429.1
JMJD6
jumonji domain containing 6
chr1_+_218458625 0.28 ENST00000366932.3
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr12_-_99288536 0.28 ENST00000549797.1
ENST00000333732.7
ENST00000341752.7
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr14_-_59950724 0.28 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr6_-_163148700 0.28 ENST00000366894.1
ENST00000338468.3
PARK2
parkin RBR E3 ubiquitin protein ligase
chr11_+_118478313 0.28 ENST00000356063.5
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr1_+_46806837 0.28 ENST00000537428.1
NSUN4
NOP2/Sun domain family, member 4
chr2_+_99953816 0.28 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr18_+_77439775 0.28 ENST00000299543.7
ENST00000075430.7
CTDP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr15_+_89905705 0.28 ENST00000560008.1
ENST00000561327.1
LINC00925
long intergenic non-protein coding RNA 925
chr1_+_25598989 0.28 ENST00000454452.2
RHD
Rh blood group, D antigen
chr6_+_44094627 0.27 ENST00000259746.9
TMEM63B
transmembrane protein 63B
chr1_-_42384343 0.27 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr2_-_148778258 0.27 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4
origin recognition complex, subunit 4
chr3_-_146187088 0.26 ENST00000497985.1
PLSCR2
phospholipid scramblase 2
chr1_-_167906277 0.26 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr19_+_19496728 0.26 ENST00000537887.1
ENST00000417582.2
GATAD2A
GATA zinc finger domain containing 2A
chr2_-_230135937 0.26 ENST00000392054.3
ENST00000409462.1
ENST00000392055.3
PID1
phosphotyrosine interaction domain containing 1
chr13_+_113548643 0.26 ENST00000375608.3
MCF2L
MCF.2 cell line derived transforming sequence-like
chr11_+_64009072 0.26 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr2_-_9770706 0.26 ENST00000381844.4
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr18_-_28681950 0.26 ENST00000251081.6
DSC2
desmocollin 2
chr22_-_42486747 0.25 ENST00000602404.1
NDUFA6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
chr2_-_161350305 0.25 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr3_-_155572164 0.25 ENST00000392845.3
ENST00000359479.3
SLC33A1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr3_-_122102065 0.25 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58
coiled-coil domain containing 58
chr10_+_104005272 0.25 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr20_+_816695 0.25 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr1_-_193029192 0.25 ENST00000417752.1
ENST00000367452.4
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr16_+_30064411 0.25 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr16_-_67694129 0.25 ENST00000602320.1
ACD
adrenocortical dysplasia homolog (mouse)
chr3_-_167452262 0.24 ENST00000487947.2
PDCD10
programmed cell death 10
chr11_-_105892937 0.24 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr13_+_73302047 0.24 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
BORA
bora, aurora kinase A activator
chr14_+_32546274 0.24 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr22_-_38484922 0.24 ENST00000428572.1
BAIAP2L2
BAI1-associated protein 2-like 2
chr14_-_51297197 0.24 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr3_-_182698381 0.23 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr10_+_95653687 0.23 ENST00000371408.3
ENST00000427197.1
SLC35G1
solute carrier family 35, member G1
chr11_+_65686728 0.23 ENST00000312515.2
ENST00000525501.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr3_-_137834436 0.23 ENST00000327532.2
ENST00000467030.1
DZIP1L
DAZ interacting zinc finger protein 1-like
chr6_-_131949305 0.23 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
MED23
mediator complex subunit 23
chr15_+_63414017 0.23 ENST00000413507.2
LACTB
lactamase, beta
chr14_+_96858433 0.23 ENST00000267584.4
AK7
adenylate kinase 7
chr1_-_31769656 0.23 ENST00000446633.2
SNRNP40
small nuclear ribonucleoprotein 40kDa (U5)
chr11_+_65686802 0.22 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr16_-_75498308 0.22 ENST00000569540.1
TMEM170A
transmembrane protein 170A
chr14_+_32546485 0.22 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr1_-_246729544 0.22 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr10_-_127511658 0.22 ENST00000368774.1
ENST00000368778.3
UROS
uroporphyrinogen III synthase
chr12_-_6579833 0.22 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr10_-_103454876 0.22 ENST00000331272.7
FBXW4
F-box and WD repeat domain containing 4
chr6_+_163148973 0.22 ENST00000366888.2
PACRG
PARK2 co-regulated
chr9_+_115983808 0.22 ENST00000374210.6
ENST00000374212.4
SLC31A1
solute carrier family 31 (copper transporter), member 1
chr14_-_104313824 0.22 ENST00000553739.1
ENST00000202556.9
PPP1R13B
protein phosphatase 1, regulatory subunit 13B
chrX_-_63615297 0.22 ENST00000374852.3
ENST00000453546.1
MTMR8
myotubularin related protein 8
chr2_-_148778323 0.21 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr19_+_49496705 0.21 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr3_+_196466710 0.21 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr16_-_69788816 0.21 ENST00000268802.5
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr14_-_67878917 0.21 ENST00000216446.4
PLEK2
pleckstrin 2
chr11_+_67183557 0.21 ENST00000445895.2
CARNS1
carnosine synthase 1
chr12_-_6579808 0.21 ENST00000535180.1
ENST00000400911.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr6_-_139613269 0.21 ENST00000358430.3
TXLNB
taxilin beta
chr7_+_102105370 0.21 ENST00000292616.5
LRWD1
leucine-rich repeats and WD repeat domain containing 1
chr2_+_230787201 0.21 ENST00000283946.3
FBXO36
F-box protein 36
chr22_+_45559722 0.21 ENST00000347635.4
ENST00000407019.2
ENST00000424634.1
ENST00000417702.1
ENST00000425733.2
ENST00000430547.1
NUP50
nucleoporin 50kDa
chr17_-_74722672 0.21 ENST00000397625.4
ENST00000445478.2
JMJD6
jumonji domain containing 6
chr14_+_24674926 0.21 ENST00000339917.5
ENST00000556621.1
ENST00000287913.6
ENST00000428351.2
ENST00000555092.1
TSSK4
testis-specific serine kinase 4
chr3_-_43147431 0.21 ENST00000441964.1
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr1_-_33283754 0.20 ENST00000373477.4
YARS
tyrosyl-tRNA synthetase
chr1_+_215256467 0.20 ENST00000391894.2
ENST00000444842.2
KCNK2
potassium channel, subfamily K, member 2
chr6_-_35888824 0.20 ENST00000361690.3
ENST00000512445.1
SRPK1
SRSF protein kinase 1
chrX_+_106045891 0.20 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1D8B
TBC1 domain family, member 8B (with GRAM domain)
chr17_-_18585131 0.20 ENST00000443457.1
ENST00000583002.1
ZNF286B
zinc finger protein 286B
chr21_+_33671160 0.20 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr13_+_29233218 0.20 ENST00000380842.4
POMP
proteasome maturation protein
chr2_+_230787213 0.20 ENST00000409992.1
FBXO36
F-box protein 36
chr12_-_26986076 0.19 ENST00000381340.3
ITPR2
inositol 1,4,5-trisphosphate receptor, type 2
chr3_-_167452298 0.19 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10
programmed cell death 10
chrX_+_131157290 0.19 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr7_+_87505544 0.19 ENST00000265728.1
DBF4
DBF4 homolog (S. cerevisiae)
chr14_-_104028595 0.19 ENST00000337322.4
ENST00000445922.2
BAG5
BCL2-associated athanogene 5
chr3_-_43147549 0.19 ENST00000344697.2
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr20_+_48807351 0.19 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr13_-_73301819 0.19 ENST00000377818.3
MZT1
mitotic spindle organizing protein 1
chr1_+_209757051 0.18 ENST00000009105.1
ENST00000423146.1
ENST00000361322.2
CAMK1G
calcium/calmodulin-dependent protein kinase IG
chr1_+_213031570 0.18 ENST00000366971.4
FLVCR1
feline leukemia virus subgroup C cellular receptor 1
chr1_+_150459873 0.18 ENST00000438568.2
ENST00000369054.2
ENST00000369064.3
ENST00000606933.1
TARS2
threonyl-tRNA synthetase 2, mitochondrial (putative)
chr10_+_106014468 0.18 ENST00000369710.4
ENST00000369713.5
ENST00000445155.1
GSTO1
glutathione S-transferase omega 1
chr5_-_102455801 0.18 ENST00000508629.1
ENST00000399004.2
GIN1
gypsy retrotransposon integrase 1
chr3_-_135914615 0.18 ENST00000309993.2
MSL2
male-specific lethal 2 homolog (Drosophila)
chr17_-_72772462 0.18 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr1_+_110527308 0.18 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr18_+_43246028 0.18 ENST00000589658.1
SLC14A2
solute carrier family 14 (urea transporter), member 2
chr13_-_20767037 0.18 ENST00000382848.4
GJB2
gap junction protein, beta 2, 26kDa
chr11_+_65479462 0.18 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
KAT5
K(lysine) acetyltransferase 5
chr17_-_76836963 0.18 ENST00000312010.6
USP36
ubiquitin specific peptidase 36
chr5_+_148724993 0.18 ENST00000513661.1
ENST00000329271.3
ENST00000416916.2
GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr18_-_48346298 0.18 ENST00000398439.3
MRO
maestro
chr3_-_131221790 0.17 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
MRPL3
mitochondrial ribosomal protein L3
chr12_+_95611569 0.17 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chrX_+_131157322 0.17 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chr19_-_19302931 0.17 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr19_+_48867652 0.17 ENST00000344846.2
SYNGR4
synaptogyrin 4
chr17_-_33416231 0.17 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 3.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.4 1.1 GO:0060458 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) right lung development(GO:0060458)
0.3 1.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 0.9 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.3 0.9 GO:2001226 negative regulation of anion channel activity(GO:0010360) negative regulation of chloride transport(GO:2001226)
0.3 1.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3 0.5 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.3 1.0 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2 0.7 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.2 2.3 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 1.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.5 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.7 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.4 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 1.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.5 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.8 GO:0070141 response to UV-A(GO:0070141)
0.1 0.4 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.7 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.6 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.3 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.3 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.5 GO:0060214 endocardium formation(GO:0060214)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.0 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.6 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.1 0.4 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.3 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.3 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.9 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.1 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.1 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.5 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.2 GO:0003249 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.1 0.4 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.2 GO:0003285 septum secundum development(GO:0003285)
0.0 0.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.5 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.3 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.2 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0060844 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 2.0 GO:1901998 toxin transport(GO:1901998)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.2 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.3 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.0 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0071557 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.3 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:2000611 positive regulation of thyroid hormone generation(GO:2000611)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.0 GO:0044209 AMP salvage(GO:0044209)
0.0 0.3 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.0 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.0 0.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 2.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.0 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0014041 regulation of neuron maturation(GO:0014041)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.2 0.5 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 1.3 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.7 GO:0070187 telosome(GO:0070187)
0.1 5.6 GO:0015030 Cajal body(GO:0015030)
0.1 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 1.2 GO:0032059 bleb(GO:0032059)
0.1 0.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 0.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.1 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.8 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 3.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 2.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.0 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 1.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.5 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 1.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.3 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.4 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.4 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.3 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.3 GO:0030395 lactose binding(GO:0030395)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 4.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.9 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 1.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 2.7 GO:0004386 helicase activity(GO:0004386)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.0 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.0 PID ATM PATHWAY ATM pathway
0.0 0.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 ST GAQ PATHWAY G alpha q Pathway
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 4.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation