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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for EP300

Z-value: 0.84

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Transcription factors associated with EP300

Gene Symbol Gene ID Gene Info
ENSG00000100393.9 E1A binding protein p300

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EP300hg19_v2_chr22_+_41487711_41487798-0.682.0e-04Click!

Activity profile of EP300 motif

Sorted Z-values of EP300 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_102188224 3.49 ENST00000263464.3
baculoviral IAP repeat containing 3
chr11_+_102188272 2.96 ENST00000532808.1
baculoviral IAP repeat containing 3
chr6_-_29595779 2.94 ENST00000355973.3
ENST00000377012.4
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_-_95007193 2.65 ENST00000370207.4
ENST00000334047.7
coagulation factor III (thromboplastin, tissue factor)
chr3_-_158450475 2.24 ENST00000237696.5
retinoic acid receptor responder (tazarotene induced) 1
chr10_-_49812997 2.15 ENST00000417912.2
Rho GTPase activating protein 22
chr6_+_126240442 2.14 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
nuclear receptor coactivator 7
chr2_-_208030647 2.06 ENST00000309446.6
Kruppel-like factor 7 (ubiquitous)
chr16_+_50776021 1.73 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
cylindromatosis (turban tumor syndrome)
chr1_-_161102367 1.73 ENST00000464113.1
death effector domain containing
chr10_-_49813090 1.66 ENST00000249601.4
Rho GTPase activating protein 22
chr16_+_50775948 1.61 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
cylindromatosis (turban tumor syndrome)
chr12_-_57505121 1.57 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
signal transducer and activator of transcription 6, interleukin-4 induced
chr16_+_50775971 1.51 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
cylindromatosis (turban tumor syndrome)
chr2_-_204400113 1.51 ENST00000319170.5
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr1_+_206643787 1.50 ENST00000367120.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr1_-_161102213 1.42 ENST00000458050.2
death effector domain containing
chr2_+_232063436 1.35 ENST00000440107.1
armadillo repeat containing 9
chr11_-_57194550 1.34 ENST00000528187.1
ENST00000524863.1
ENST00000533051.1
ENST00000529494.1
ENST00000395124.1
ENST00000533524.1
ENST00000533245.1
ENST00000530316.1
solute carrier family 43, member 3
chr1_-_161102421 1.32 ENST00000490843.2
ENST00000368006.3
ENST00000392188.1
ENST00000545495.1
death effector domain containing
chr6_-_10415218 1.31 ENST00000466073.1
ENST00000498450.1
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr11_-_3862059 1.21 ENST00000396978.1
ras homolog family member G
chr18_-_33709268 1.20 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
solute carrier family 39 (zinc transporter), member 6
chr1_-_33336414 1.18 ENST00000373471.3
ENST00000609187.1
fibronectin type III domain containing 5
chr3_-_79816965 1.13 ENST00000464233.1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_+_206643806 1.11 ENST00000537984.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr3_+_105086056 1.05 ENST00000472644.2
activated leukocyte cell adhesion molecule
chr8_+_106330920 1.04 ENST00000407775.2
zinc finger protein, FOG family member 2
chr17_+_21187976 1.03 ENST00000342679.4
mitogen-activated protein kinase kinase 3
chr11_-_18610214 1.03 ENST00000300038.7
ENST00000396197.3
ENST00000320750.6
UEV and lactate/malate dehyrogenase domains
chr3_+_105085734 1.00 ENST00000306107.5
activated leukocyte cell adhesion molecule
chr20_+_32399093 0.98 ENST00000217402.2
charged multivesicular body protein 4B
chr19_-_1174226 0.98 ENST00000587024.1
ENST00000361757.3
strawberry notch homolog 2 (Drosophila)
chr4_+_15704679 0.97 ENST00000382346.3
bone marrow stromal cell antigen 1
chr4_+_8201091 0.93 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3 domain and tetratricopeptide repeats 1
chr11_-_18610246 0.92 ENST00000379387.4
ENST00000541984.1
UEV and lactate/malate dehyrogenase domains
chr16_+_84682108 0.90 ENST00000564996.1
ENST00000258157.5
ENST00000567410.1
kelch-like family member 36
chr5_+_56111361 0.90 ENST00000399503.3
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr16_+_69373323 0.89 ENST00000254940.5
NIP7, nucleolar pre-rRNA processing protein
chr11_-_57194418 0.83 ENST00000395123.2
ENST00000530005.1
ENST00000532278.1
solute carrier family 43, member 3
chr20_-_30311703 0.82 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2-like 1
chr7_+_108210012 0.81 ENST00000249356.3
DnaJ (Hsp40) homolog, subfamily B, member 9
chr15_+_74287118 0.79 ENST00000563500.1
promyelocytic leukemia
chr12_+_72058130 0.78 ENST00000547843.1
THAP domain containing, apoptosis associated protein 2
chr4_+_56815102 0.78 ENST00000257287.4
centrosomal protein 135kDa
chr11_-_123612319 0.76 ENST00000526252.1
ENST00000530393.1
ENST00000533463.1
ENST00000336139.4
ENST00000529691.1
ENST00000528306.1
zinc finger protein 202
chr2_-_3606206 0.76 ENST00000315212.3
ribonuclease H1
chr22_-_43042955 0.76 ENST00000402438.1
cytochrome b5 reductase 3
chr17_+_7255208 0.74 ENST00000333751.3
potassium channel tetramerization domain containing 11
chr3_-_172428959 0.73 ENST00000475381.1
ENST00000538775.1
ENST00000273512.3
ENST00000543711.1
neutral cholesterol ester hydrolase 1
chr11_+_62623544 0.72 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_-_244013384 0.72 ENST00000366539.1
v-akt murine thymoma viral oncogene homolog 3
chr7_+_48128854 0.71 ENST00000436673.1
ENST00000429491.2
uridine phosphorylase 1
chr6_-_33290580 0.71 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
death-domain associated protein
chr3_-_71632894 0.71 ENST00000493089.1
forkhead box P1
chr11_-_3862206 0.71 ENST00000351018.4
ras homolog family member G
chr16_+_31085714 0.70 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
zinc finger protein 646
chr11_+_62623621 0.69 ENST00000535296.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_+_62623512 0.68 ENST00000377892.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr19_+_10362882 0.68 ENST00000393733.2
ENST00000588502.1
mitochondrial ribosomal protein L4
chr12_+_52463751 0.67 ENST00000336854.4
ENST00000550604.1
ENST00000553049.1
ENST00000548915.1
chromosome 12 open reading frame 44
chr19_-_55658687 0.67 ENST00000593046.1
troponin T type 1 (skeletal, slow)
chr1_+_170501270 0.66 ENST00000367763.3
ENST00000367762.1
golgin, RAB6-interacting
chr7_-_5569588 0.65 ENST00000417101.1
actin, beta
chr16_+_69373661 0.65 ENST00000254941.6
NIP7, nucleolar pre-rRNA processing protein
chr6_-_35888824 0.64 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr12_+_69004619 0.63 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B, member of RAS oncogene family
chr12_+_117348742 0.62 ENST00000309909.5
ENST00000455858.2
F-box and WD repeat domain containing 8
chr6_-_35888905 0.62 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr15_+_74287035 0.62 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
promyelocytic leukemia
chr22_-_50963976 0.61 ENST00000252785.3
ENST00000395693.3
SCO2 cytochrome c oxidase assembly protein
chr11_-_57092381 0.61 ENST00000358252.3
tankyrase 1 binding protein 1, 182kDa
chr5_+_68530668 0.61 ENST00000506563.1
cyclin-dependent kinase 7
chr6_+_29910301 0.60 ENST00000376809.5
ENST00000376802.2
major histocompatibility complex, class I, A
chr16_+_2732476 0.60 ENST00000301738.4
ENST00000564195.1
potassium channel tetramerization domain containing 5
chr5_+_68530697 0.60 ENST00000256443.3
ENST00000514676.1
cyclin-dependent kinase 7
chr8_+_17434689 0.60 ENST00000398074.3
platelet-derived growth factor receptor-like
chr15_+_74287009 0.59 ENST00000395135.3
promyelocytic leukemia
chr11_+_2421718 0.58 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
tumor suppressing subtransferable candidate 4
chr1_-_43855444 0.58 ENST00000372455.4
mediator complex subunit 8
chr12_+_116997186 0.57 ENST00000306985.4
microtubule-associated protein 1 light chain 3 beta 2
chr17_+_37783170 0.57 ENST00000254079.4
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr18_+_77439775 0.55 ENST00000299543.7
ENST00000075430.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr8_-_33424636 0.55 ENST00000256257.1
ring finger protein 122
chr8_-_134309335 0.54 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
N-myc downstream regulated 1
chr10_-_43892668 0.53 ENST00000544000.1
heterogeneous nuclear ribonucleoprotein F
chr11_+_64323098 0.53 ENST00000301891.4
solute carrier family 22 (organic anion/urate transporter), member 11
chr17_-_76836963 0.53 ENST00000312010.6
ubiquitin specific peptidase 36
chr20_+_32951070 0.52 ENST00000535650.1
ENST00000262650.6
itchy E3 ubiquitin protein ligase
chr5_-_892648 0.52 ENST00000483173.1
ENST00000435709.2
bromodomain containing 9
chr19_+_10362577 0.51 ENST00000592514.1
ENST00000307422.5
ENST00000253099.6
ENST00000590150.1
ENST00000590669.1
mitochondrial ribosomal protein L4
chr19_+_16187085 0.51 ENST00000300933.4
tropomyosin 4
chr16_+_66400533 0.50 ENST00000341529.3
cadherin 5, type 2 (vascular endothelium)
chr6_+_31865552 0.50 ENST00000469372.1
ENST00000497706.1
complement component 2
chr1_-_155658260 0.50 ENST00000368339.5
ENST00000405763.3
ENST00000368340.5
ENST00000454523.1
ENST00000443231.1
ENST00000347088.5
ENST00000361831.5
ENST00000355499.4
YY1 associated protein 1
chr2_-_229046361 0.50 ENST00000392056.3
SPHK1 interactor, AKAP domain containing
chr4_+_110736659 0.50 ENST00000394631.3
ENST00000226796.6
GAR1 ribonucleoprotein
chr19_-_11545920 0.49 ENST00000356392.4
ENST00000591179.1
coiled-coil domain containing 151
chr19_-_11039261 0.49 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
Yip1 domain family, member 2
chr11_+_64323156 0.49 ENST00000377585.3
solute carrier family 22 (organic anion/urate transporter), member 11
chr11_-_34535332 0.48 ENST00000257832.2
ENST00000429939.2
E74-like factor 5 (ets domain transcription factor)
chr11_-_63258601 0.48 ENST00000540857.1
ENST00000539221.1
ENST00000301790.4
HRAS-like suppressor family, member 5
chr11_-_104905840 0.48 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr1_+_95582881 0.48 ENST00000370203.4
ENST00000456991.1
transmembrane protein 56
chr2_-_229046330 0.48 ENST00000344657.5
SPHK1 interactor, AKAP domain containing
chr19_+_17186577 0.48 ENST00000595618.1
ENST00000594824.1
myosin IXB
chr22_-_43042968 0.47 ENST00000407623.3
ENST00000396303.3
ENST00000438270.1
cytochrome b5 reductase 3
chr1_+_18434240 0.47 ENST00000251296.1
immunoglobin superfamily, member 21
chr21_-_38639601 0.47 ENST00000539844.1
ENST00000476950.1
ENST00000399001.1
Down syndrome critical region gene 3
chr9_-_33473882 0.46 ENST00000455041.2
ENST00000353159.2
ENST00000297990.4
ENST00000379471.2
nucleolar protein 6 (RNA-associated)
chr5_+_140345820 0.45 ENST00000289269.5
protocadherin alpha subfamily C, 2
chr11_-_3663502 0.45 ENST00000359918.4
ADP-ribosyltransferase 5
chrX_+_149861836 0.45 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
myotubularin related protein 1
chr19_-_18649181 0.45 ENST00000596015.1
FK506 binding protein 8, 38kDa
chr9_-_133814455 0.45 ENST00000448616.1
fibrinogen C domain containing 1
chr14_-_89021077 0.44 ENST00000556564.1
protein tyrosine phosphatase, non-receptor type 21
chr12_-_6740802 0.44 ENST00000431922.1
lysophosphatidic acid receptor 5
chr8_-_134309823 0.44 ENST00000414097.2
N-myc downstream regulated 1
chr17_+_7487146 0.44 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr16_+_29984962 0.44 ENST00000308893.4
TAO kinase 2
chr6_-_35992270 0.43 ENST00000394602.2
ENST00000355574.2
solute carrier family 26 (anion exchanger), member 8
chr14_-_38064198 0.43 ENST00000250448.2
forkhead box A1
chr11_-_3663480 0.43 ENST00000397068.3
ADP-ribosyltransferase 5
chr11_-_104035088 0.42 ENST00000302251.5
platelet derived growth factor D
chr18_+_32556892 0.42 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
microtubule-associated protein, RP/EB family, member 2
chr6_+_30457244 0.42 ENST00000376630.4
major histocompatibility complex, class I, E
chr12_+_7072354 0.42 ENST00000537269.1
U47924.27
chr10_+_45495898 0.41 ENST00000298299.3
zinc finger protein 22
chr2_-_118771701 0.41 ENST00000376300.2
ENST00000319432.5
coiled-coil domain containing 93
chr22_-_31688381 0.41 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr16_+_1832902 0.39 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
nucleotide binding protein 2
chr6_-_86352642 0.39 ENST00000355238.6
synaptotagmin binding, cytoplasmic RNA interacting protein
chr19_+_11546440 0.39 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
protein kinase C substrate 80K-H
chr9_-_123638633 0.39 ENST00000456291.1
PHD finger protein 19
chr4_+_2470664 0.39 ENST00000314289.8
ENST00000541204.1
ENST00000502316.1
ENST00000507247.1
ENST00000509258.1
ENST00000511859.1
ring finger protein 4
chr15_+_42787815 0.39 ENST00000564153.1
ENST00000349777.1
ENST00000567094.1
ENST00000566327.1
ENST00000568859.1
synaptosomal-associated protein, 23kDa
chr6_-_42162654 0.39 ENST00000230361.3
guanylate cyclase activator 1B (retina)
chr10_+_49892904 0.39 ENST00000360890.2
WDFY family member 4
chr10_-_111683183 0.38 ENST00000403138.2
ENST00000369683.1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr16_-_66968265 0.38 ENST00000567511.1
ENST00000422424.2
family with sequence similarity 96, member B
chr10_+_99400443 0.38 ENST00000370631.3
phosphatidylinositol 4-kinase type 2 alpha
chr19_-_10514184 0.38 ENST00000589629.1
ENST00000222005.2
cell division cycle 37
chr11_-_126081532 0.37 ENST00000533628.1
ENST00000298317.4
ENST00000532674.1
RNA pseudouridylate synthase domain containing 4
chr11_-_46722117 0.37 ENST00000311956.4
Rho GTPase activating protein 1
chr22_+_42470244 0.36 ENST00000321753.3
family with sequence similarity 109, member B
chr14_-_69445793 0.36 ENST00000538545.2
ENST00000394419.4
actinin, alpha 1
chr19_+_11546153 0.36 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
protein kinase C substrate 80K-H
chr1_-_1051736 0.36 ENST00000448924.1
ENST00000294576.5
ENST00000437760.1
ENST00000462097.1
ENST00000475119.1
chromosome 1 open reading frame 159
chr15_+_42787452 0.36 ENST00000249647.3
synaptosomal-associated protein, 23kDa
chr1_-_43855479 0.36 ENST00000290663.6
ENST00000372457.4
mediator complex subunit 8
chr1_-_8939265 0.35 ENST00000489867.1
enolase 1, (alpha)
chr2_+_191513789 0.35 ENST00000409581.1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr19_-_10530784 0.35 ENST00000593124.1
cell division cycle 37
chr7_-_2354099 0.35 ENST00000222990.3
sorting nexin 8
chr22_+_32340447 0.35 ENST00000248975.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr22_-_45636650 0.35 ENST00000336156.5
KIAA0930
chr6_+_43738444 0.34 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
vascular endothelial growth factor A
chr14_-_24711865 0.34 ENST00000399423.4
ENST00000267415.7
TERF1 (TRF1)-interacting nuclear factor 2
chr14_-_24711806 0.34 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TERF1 (TRF1)-interacting nuclear factor 2
chr5_-_176936844 0.34 ENST00000510380.1
ENST00000510898.1
ENST00000357198.4
docking protein 3
chr13_-_44361025 0.34 ENST00000261488.6
ecto-NOX disulfide-thiol exchanger 1
chr18_+_5238549 0.34 ENST00000580684.1
long intergenic non-protein coding RNA 667
chr1_+_22303503 0.34 ENST00000337107.6
chymotrypsin-like elastase family, member 3B
chr3_-_71802760 0.34 ENST00000295612.3
eukaryotic translation initiation factor 4E family member 3
chr21_+_45285050 0.34 ENST00000291572.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr11_-_11643540 0.33 ENST00000227756.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18
chr22_+_32340481 0.33 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr2_-_120980939 0.33 ENST00000426077.2
transmembrane protein 185B
chr1_+_43855560 0.33 ENST00000562955.1
seizure threshold 2 homolog (mouse)
chr2_-_160919112 0.33 ENST00000283243.7
ENST00000392771.1
phospholipase A2 receptor 1, 180kDa
chr17_-_79269067 0.33 ENST00000288439.5
ENST00000374759.3
solute carrier family 38, member 10
chr2_-_204400013 0.32 ENST00000374489.2
ENST00000374488.2
ENST00000308091.4
ENST00000453034.1
ENST00000420371.1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr22_-_27014043 0.32 ENST00000215939.2
crystallin, beta B1
chr2_+_233415488 0.32 ENST00000454501.1
eukaryotic translation initiation factor 4E family member 2
chr16_-_87799505 0.32 ENST00000353170.5
ENST00000561825.1
ENST00000270583.5
ENST00000562261.1
ENST00000347925.5
kelch domain containing 4
chr1_-_155658518 0.32 ENST00000404643.1
ENST00000359205.5
ENST00000407221.1
YY1 associated protein 1
chr16_-_66968055 0.32 ENST00000568572.1
family with sequence similarity 96, member B
chr19_+_1000418 0.31 ENST00000234389.3
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr22_+_37257015 0.31 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
neutrophil cytosolic factor 4, 40kDa
chr2_+_233415363 0.31 ENST00000409514.1
ENST00000409098.1
ENST00000409495.1
ENST00000409167.3
ENST00000409322.1
ENST00000409394.1
eukaryotic translation initiation factor 4E family member 2
chr14_-_24711470 0.31 ENST00000559969.1
TERF1 (TRF1)-interacting nuclear factor 2
chr20_+_32951041 0.31 ENST00000374864.4
itchy E3 ubiquitin protein ligase
chr19_-_44809121 0.31 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
zinc finger protein 235
chr7_+_45197383 0.31 ENST00000242249.4
ENST00000496212.1
ENST00000481345.1
receptor (G protein-coupled) activity modifying protein 3
chr19_-_49955050 0.31 ENST00000262265.5
PIH1 domain containing 1
chr19_-_55658281 0.31 ENST00000585321.2
ENST00000587465.2
troponin T type 1 (skeletal, slow)
chr10_-_99161033 0.30 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr14_-_69445968 0.30 ENST00000438964.2
actinin, alpha 1
chr5_-_32444828 0.30 ENST00000265069.8
zinc finger RNA binding protein
chr3_+_19988885 0.29 ENST00000422242.1
RAB5A, member RAS oncogene family
chr4_+_56814968 0.29 ENST00000422247.2
centrosomal protein 135kDa
chr17_-_71308119 0.29 ENST00000439510.2
ENST00000581014.1
ENST00000579611.1
CDC42 effector protein (Rho GTPase binding) 4
chr10_+_98592009 0.28 ENST00000540664.1
ENST00000371103.3
ligand dependent nuclear receptor corepressor
chrX_+_153665248 0.28 ENST00000447750.2
GDP dissociation inhibitor 1
chr16_-_58585513 0.28 ENST00000245138.4
ENST00000567285.1
CCR4-NOT transcription complex, subunit 1
chr3_-_49761337 0.28 ENST00000535833.1
ENST00000308388.6
ENST00000480687.1
ENST00000308375.6
adhesion molecule with Ig-like domain 3
GDP-mannose pyrophosphorylase B
chr3_+_171758344 0.28 ENST00000336824.4
ENST00000423424.1
fibronectin type III domain containing 3B
chr12_-_118406777 0.28 ENST00000339824.5
kinase suppressor of ras 2
chr2_+_231280908 0.28 ENST00000427101.2
ENST00000432979.1
SP100 nuclear antigen
chr16_-_31085514 0.28 ENST00000300849.4
zinc finger protein 668

Network of associatons between targets according to the STRING database.

First level regulatory network of EP300

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:1990108 protein linear deubiquitination(GO:1990108)
0.9 2.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.5 6.5 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.4 2.1 GO:0060356 leucine import(GO:0060356)
0.4 1.6 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.4 1.1 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.3 1.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 1.3 GO:0003409 optic cup structural organization(GO:0003409)
0.3 0.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 2.0 GO:0030578 PML body organization(GO:0030578)
0.2 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 0.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.7 GO:0006218 uridine catabolic process(GO:0006218)
0.2 0.7 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.2 0.9 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.2 0.8 GO:0035519 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.2 0.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 1.0 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.2 1.0 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.4 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.7 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 0.4 GO:0032759 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) protection from natural killer cell mediated cytotoxicity(GO:0042270) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 1.0 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.4 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 2.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.7 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 1.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.3 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 2.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 1.0 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.5 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.6 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.3 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.8 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 1.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.3 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 0.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.5 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 0.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.0 GO:0015747 urate transport(GO:0015747)
0.1 1.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.5 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 2.1 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 1.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.2 GO:0031446 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 1.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.5 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.1 2.9 GO:0007214 negative regulation of adenylate cyclase activity(GO:0007194) gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.4 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 1.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.2 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.7 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.2 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.2 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1 0.2 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.5 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 1.1 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 1.3 GO:0030033 microvillus assembly(GO:0030033)
0.0 2.2 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.6 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.2 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.4 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 4.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.6 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.4 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.6 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.4 GO:0019532 oxalate transport(GO:0019532)
0.0 0.6 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.7 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.7 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.9 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0071545 inositol phosphate catabolic process(GO:0071545)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.9 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.3 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.3 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0071503 positive regulation of lipoprotein particle clearance(GO:0010986) response to heparin(GO:0071503)
0.0 0.3 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.5 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.7 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 0.1 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.3 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0 1.8 GO:0048675 axon extension(GO:0048675)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 1.0 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.0 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 1.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 1.2 GO:0070125 mitochondrial translational elongation(GO:0070125)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 1.2 GO:0070985 TFIIK complex(GO:0070985)
0.3 2.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 1.0 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.2 0.9 GO:0071817 MMXD complex(GO:0071817)
0.1 0.7 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.1 0.9 GO:1990393 3M complex(GO:1990393)
0.1 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 2.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.5 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.2 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 1.2 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.4 GO:0035838 growing cell tip(GO:0035838)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 0.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 3.9 GO:0097542 ciliary tip(GO:0097542)
0.1 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 2.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.1 1.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 1.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.9 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 2.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 2.9 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 6.7 GO:0045121 membrane raft(GO:0045121)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.4 GO:0030175 filopodium(GO:0030175)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.7 2.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 4.9 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.3 1.0 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.3 0.9 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.2 0.6 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.2 0.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.6 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.7 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 3.1 GO:0032183 SUMO binding(GO:0032183)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 6.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.7 GO:0004771 sterol esterase activity(GO:0004771)
0.1 1.2 GO:0031014 troponin T binding(GO:0031014)
0.1 1.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.4 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.3 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.6 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.8 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.3 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 2.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0008061 chitin binding(GO:0008061)
0.0 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 2.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0052847 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 2.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 5.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 1.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 6.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 3.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 3.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 3.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 0.9 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 3.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 0.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 1.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 1.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 3.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 2.1 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes