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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ESR1

Z-value: 1.06

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Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ENSG00000091831.17 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESR1hg19_v2_chr6_+_152128810_1521288270.385.9e-02Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_23046750 4.57 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr12_-_42877726 3.65 ENST00000548696.1
prickle homolog 1 (Drosophila)
chr1_+_212458834 2.89 ENST00000261461.2
protein phosphatase 2, regulatory subunit B', alpha
chr12_-_42877764 2.61 ENST00000455697.1
prickle homolog 1 (Drosophila)
chr3_-_148804275 2.30 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr22_+_22936998 2.18 ENST00000390303.2
immunoglobulin lambda variable 3-32 (non-functional)
chr12_-_95044309 1.91 ENST00000261226.4
transmembrane and coiled-coil domain family 3
chr19_-_1513188 1.91 ENST00000330475.4
ADAMTS-like 5
chr3_+_38017264 1.85 ENST00000436654.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr3_-_122512619 1.84 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr20_-_45981138 1.83 ENST00000446994.2
zinc finger, MYND-type containing 8
chr3_+_37903432 1.81 ENST00000443503.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr9_-_134151915 1.77 ENST00000372271.3
family with sequence similarity 78, member A
chr16_-_88772670 1.75 ENST00000562544.1
ring finger protein 166
chr16_-_88772761 1.65 ENST00000567844.1
ENST00000312838.4
ring finger protein 166
chr19_-_18995029 1.52 ENST00000596048.1
ceramide synthase 1
chr13_+_103451548 1.52 ENST00000419638.1
basic, immunoglobulin-like variable motif containing
chr8_-_28243590 1.52 ENST00000523095.1
ENST00000522795.1
zinc finger protein 395
chr19_+_58790314 1.51 ENST00000196548.5
ENST00000608843.1
Zinc finger protein 8
zinc finger protein 8
chr13_+_103451399 1.47 ENST00000257336.1
ENST00000448849.2
basic, immunoglobulin-like variable motif containing
chr11_+_47270436 1.47 ENST00000395397.3
ENST00000405576.1
nuclear receptor subfamily 1, group H, member 3
chr11_+_47270475 1.44 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
nuclear receptor subfamily 1, group H, member 3
chr4_-_89080003 1.43 ENST00000237612.3
ATP-binding cassette, sub-family G (WHITE), member 2
chr19_+_50194360 1.42 ENST00000323446.5
ENST00000392518.4
ENST00000598396.1
ENST00000598293.1
ENST00000354199.5
ENST00000405931.2
ENST00000602019.1
carnitine palmitoyltransferase 1C
chr8_-_28243934 1.42 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
zinc finger protein 395
chr2_-_86094764 1.42 ENST00000393808.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_+_233925064 1.37 ENST00000359570.5
ENST00000538935.1
inositol polyphosphate-5-phosphatase, 145kDa
chr13_-_103451307 1.37 ENST00000376004.4
KDEL (Lys-Asp-Glu-Leu) containing 1
chr14_-_106453155 1.35 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr3_+_58223228 1.31 ENST00000478253.1
ENST00000295962.4
abhydrolase domain containing 6
chr11_-_118134997 1.31 ENST00000278937.2
myelin protein zero-like 2
chr17_-_46688334 1.29 ENST00000239165.7
homeobox B7
chr2_-_132559234 1.26 ENST00000303798.2
chromosome 2 open reading frame 27B
chr4_-_99578776 1.24 ENST00000515287.1
tetraspanin 5
chr19_-_13213662 1.21 ENST00000264824.4
lymphoblastic leukemia derived sequence 1
chr1_+_901847 1.15 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
pleckstrin homology domain containing, family N member 1
chr10_+_54074033 1.10 ENST00000373970.3
dickkopf WNT signaling pathway inhibitor 1
chr16_-_75300679 1.08 ENST00000420641.3
breast cancer anti-estrogen resistance 1
chr22_+_32455111 1.06 ENST00000543737.1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr4_-_99578789 1.06 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chr10_-_7513904 1.03 ENST00000420395.1
RP5-1031D4.2
chr4_-_140201333 1.02 ENST00000398955.1
mitochondria-localized glutamic acid-rich protein
chr9_+_140172200 1.02 ENST00000357503.2
torsin family 4, member A
chr3_-_183735651 1.01 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr1_-_16763685 0.99 ENST00000540400.1
spermatogenesis associated 21
chr6_+_32121789 0.93 ENST00000437001.2
ENST00000375137.2
palmitoyl-protein thioesterase 2
chr6_+_24495067 0.92 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr6_+_32121908 0.90 ENST00000375143.2
ENST00000424499.1
palmitoyl-protein thioesterase 2
chr14_-_105420241 0.90 ENST00000557457.1
AHNAK nucleoprotein 2
chr14_+_89290965 0.88 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
tetratricopeptide repeat domain 8
chr2_+_191208196 0.86 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
inositol polyphosphate-1-phosphatase
chrX_+_77166172 0.86 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr20_+_1246908 0.86 ENST00000381873.3
ENST00000381867.1
syntaphilin
chr22_+_29702996 0.86 ENST00000406549.3
ENST00000360113.2
ENST00000341313.6
ENST00000403764.1
ENST00000471961.1
ENST00000407854.1
growth arrest-specific 2 like 1
chr1_+_16083154 0.83 ENST00000375771.1
filamin binding LIM protein 1
chr6_+_24495185 0.83 ENST00000348925.2
aldehyde dehydrogenase 5 family, member A1
chr19_+_7011509 0.83 ENST00000377296.3
Uncharacterized protein
chr1_-_59043166 0.82 ENST00000371225.2
tumor-associated calcium signal transducer 2
chr7_-_132261253 0.82 ENST00000321063.4
plexin A4
chr19_-_49176264 0.81 ENST00000270235.4
ENST00000596844.1
netrin 5
chr16_+_89894875 0.81 ENST00000393062.2
spire-type actin nucleation factor 2
chr17_-_39677971 0.80 ENST00000393976.2
keratin 15
chr3_-_183735731 0.80 ENST00000334444.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr17_+_37793318 0.79 ENST00000336308.5
StAR-related lipid transfer (START) domain containing 3
chr6_-_2971429 0.79 ENST00000380529.1
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr19_-_19051993 0.77 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
homer homolog 3 (Drosophila)
chr14_-_106066376 0.76 ENST00000412518.1
ENST00000428654.1
ENST00000427543.1
ENST00000420153.1
ENST00000577108.1
ENST00000576077.1
AL928742.12
immunoglobulin heavy constant epsilon
chr6_+_32121218 0.76 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
palmitoyl-protein thioesterase 2
chr14_-_75536182 0.76 ENST00000555463.1
acylphosphatase 1, erythrocyte (common) type
chr11_+_33563821 0.75 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549-like
chr6_-_2971494 0.74 ENST00000380539.1
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr13_+_37006398 0.74 ENST00000418263.1
cyclin A1
chr22_-_37880543 0.73 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_-_17375527 0.72 ENST00000431146.2
ENST00000594190.1
Usher syndrome 1C binding protein 1
chr7_-_16685422 0.72 ENST00000306999.2
ankyrin repeat and MYND domain containing 2
chr5_+_110559784 0.72 ENST00000282356.4
calcium/calmodulin-dependent protein kinase IV
chr11_-_47270341 0.71 ENST00000529444.1
ENST00000530453.1
ENST00000537863.1
ENST00000529788.1
ENST00000444355.2
ENST00000527256.1
ENST00000529663.1
ENST00000256997.3
acid phosphatase 2, lysosomal
chr12_-_14996355 0.71 ENST00000228936.4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr6_-_111804905 0.71 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr22_+_23165153 0.71 ENST00000390317.2
immunoglobulin lambda variable 2-8
chr11_+_3876859 0.70 ENST00000300737.4
stromal interaction molecule 1
chr4_-_10023095 0.69 ENST00000264784.3
solute carrier family 2 (facilitated glucose transporter), member 9
chr6_+_139094657 0.69 ENST00000332797.6
coiled-coil domain containing 28A
chr17_+_37793378 0.69 ENST00000544210.2
ENST00000581894.1
ENST00000394250.4
ENST00000579479.1
ENST00000577248.1
ENST00000580611.1
StAR-related lipid transfer (START) domain containing 3
chr7_+_94139105 0.68 ENST00000297273.4
CAS1 domain containing 1
chr9_+_128509663 0.67 ENST00000373489.5
ENST00000373483.2
pre-B-cell leukemia homeobox 3
chr5_+_170288856 0.66 ENST00000523189.1
RAN binding protein 17
chr19_+_46002868 0.66 ENST00000396735.2
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr12_+_125478241 0.66 ENST00000341446.8
BRI3 binding protein
chr3_-_46506358 0.65 ENST00000417439.1
ENST00000431944.1
lactotransferrin
chr10_+_81466084 0.64 ENST00000342531.2
NUT family member 2B
chr14_-_67955426 0.64 ENST00000554480.1
transmembrane protein 229B
chr17_-_19771242 0.64 ENST00000361658.2
unc-51 like autophagy activating kinase 2
chr11_+_64107663 0.64 ENST00000356786.5
coiled-coil domain containing 88B
chr3_+_48488114 0.62 ENST00000421175.1
ENST00000320211.3
ENST00000346691.4
ENST00000357105.6
ATR interacting protein
chr13_+_37006421 0.62 ENST00000255465.4
cyclin A1
chr11_+_123396528 0.62 ENST00000322282.7
ENST00000529750.1
GRAM domain containing 1B
chr3_-_128294929 0.62 ENST00000356020.2
chromosome 3 open reading frame 27
chr1_+_43291220 0.62 ENST00000372514.3
erythroblast membrane-associated protein (Scianna blood group)
chr1_+_245133656 0.62 ENST00000366521.3
EF-hand calcium binding domain 2
chr19_-_58864848 0.62 ENST00000263100.3
alpha-1-B glycoprotein
chr11_+_57310114 0.60 ENST00000527972.1
ENST00000399154.2
smoothelin-like 1
chr22_-_51016433 0.60 ENST00000405237.3
carnitine palmitoyltransferase 1B (muscle)
chr13_+_37005967 0.58 ENST00000440264.1
ENST00000449823.1
cyclin A1
chr6_-_2903514 0.58 ENST00000380698.4
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr1_+_33231268 0.58 ENST00000373480.1
KIAA1522
chr6_+_24775153 0.57 ENST00000356509.3
ENST00000230056.3
geminin, DNA replication inhibitor
chr10_-_103880209 0.57 ENST00000425280.1
LIM domain binding 1
chr3_+_42897512 0.57 ENST00000493193.1
atypical chemokine receptor 2
chr11_+_62439126 0.57 ENST00000377953.3
chromosome 11 open reading frame 83
chr11_-_66445219 0.56 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RNA binding motif protein 4B
chr6_-_32122106 0.56 ENST00000428778.1
proline-rich transmembrane protein 1
chr14_-_105531759 0.56 ENST00000329797.3
ENST00000539291.2
ENST00000392585.2
G protein-coupled receptor 132
chr7_+_149535455 0.56 ENST00000223210.4
ENST00000460379.1
zinc finger protein 862
chr8_-_71316021 0.55 ENST00000452400.2
nuclear receptor coactivator 2
chr22_+_31277661 0.54 ENST00000454145.1
ENST00000453621.1
ENST00000431368.1
ENST00000535268.1
oxysterol binding protein 2
chr2_+_177015122 0.54 ENST00000468418.3
homeobox D3
chr4_-_101111615 0.54 ENST00000273990.2
DNA-damage-inducible transcript 4-like
chr19_-_17375541 0.53 ENST00000252597.3
Usher syndrome 1C binding protein 1
chr11_-_63376013 0.53 ENST00000540943.1
phospholipase A2, group XVI
chr7_-_99766191 0.52 ENST00000423751.1
ENST00000360039.4
galactose-3-O-sulfotransferase 4
chrX_-_148676974 0.52 ENST00000524178.1
heat shock transcription factor family, X linked 2
chr16_-_10652993 0.52 ENST00000536829.1
epithelial membrane protein 2
chr3_-_33759699 0.51 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
cytoplasmic linker associated protein 2
chr8_-_101571964 0.51 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ankyrin repeat domain 46
chr2_+_182756615 0.51 ENST00000431877.2
ENST00000320370.7
sperm specific antigen 2
chr2_+_242750274 0.51 ENST00000405370.1
sialidase 4
chr17_+_31254892 0.51 ENST00000394642.3
ENST00000579849.1
transmembrane protein 98
chr1_-_204121102 0.50 ENST00000367202.4
ethanolamine kinase 2
chr17_-_76274572 0.50 ENST00000374945.1
RP11-219G17.4
chr1_-_40137710 0.50 ENST00000235628.1
5'-nucleotidase, cytosolic IA
chrX_+_148855726 0.50 ENST00000370416.4
heat shock transcription factor family, X linked 1
chr4_+_25915822 0.49 ENST00000506197.2
small integral membrane protein 20
chr5_-_73936451 0.49 ENST00000537006.1
ectodermal-neural cortex 1 (with BTB domain)
chr11_+_65190245 0.48 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr3_-_33759541 0.48 ENST00000468888.2
cytoplasmic linker associated protein 2
chr6_+_28092338 0.48 ENST00000340487.4
zinc finger and SCAN domain containing 16
chr9_+_141107506 0.48 ENST00000446912.2
family with sequence similarity 157, member B
chr8_-_41522719 0.48 ENST00000335651.6
ankyrin 1, erythrocytic
chr12_+_112204691 0.48 ENST00000416293.3
ENST00000261733.2
aldehyde dehydrogenase 2 family (mitochondrial)
chr10_+_74870253 0.48 ENST00000544879.1
ENST00000537969.1
ENST00000372997.3
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr8_-_145690724 0.48 ENST00000526887.1
ENST00000533764.1
ENST00000403000.2
cysteine/histidine-rich 1
chr9_-_127263265 0.47 ENST00000373587.3
nuclear receptor subfamily 5, group A, member 1
chr7_+_155090271 0.47 ENST00000476756.1
insulin induced gene 1
chr1_-_24151892 0.47 ENST00000235958.4
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr1_-_24151903 0.47 ENST00000436439.2
ENST00000374490.3
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr14_-_91884150 0.46 ENST00000553403.1
coiled-coil domain containing 88C
chr12_+_123874589 0.46 ENST00000437502.1
SET domain containing (lysine methyltransferase) 8
chr13_-_99174252 0.46 ENST00000376547.3
serine/threonine kinase 24
chr19_-_2740036 0.46 ENST00000586572.1
ENST00000269740.4
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chr17_-_41277467 0.46 ENST00000494123.1
ENST00000346315.3
ENST00000309486.4
ENST00000468300.1
ENST00000354071.3
ENST00000352993.3
ENST00000471181.2
breast cancer 1, early onset
chr17_-_34592032 0.46 ENST00000457979.3
TBC1 domain family, member 3C
chr14_+_105992906 0.45 ENST00000392519.2
transmembrane protein 121
chr2_+_219264466 0.45 ENST00000273062.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr14_-_106054659 0.45 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr10_+_76586348 0.45 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr1_+_94883991 0.44 ENST00000370214.4
ATP-binding cassette, sub-family D (ALD), member 3
chr7_-_134001663 0.44 ENST00000378509.4
solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
chr12_-_52585765 0.44 ENST00000313234.5
ENST00000394815.2
keratin 80
chr3_-_125775629 0.44 ENST00000383598.2
solute carrier family 41, member 3
chr5_+_32710736 0.44 ENST00000415685.2
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr3_-_93781750 0.44 ENST00000314636.2
dihydrofolate reductase-like 1
chr17_+_43922241 0.43 ENST00000329196.5
signal peptide peptidase like 2C
chr10_+_74870206 0.43 ENST00000357321.4
ENST00000349051.5
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr1_-_16763911 0.43 ENST00000375577.1
ENST00000335496.1
spermatogenesis associated 21
chr8_+_42010464 0.43 ENST00000518421.1
ENST00000174653.3
ENST00000396926.3
ENST00000521280.1
ENST00000522288.1
adaptor-related protein complex 3, mu 2 subunit
chr17_+_36283971 0.42 ENST00000327454.6
ENST00000378174.5
TBC1 domain family, member 3F
chr22_-_21579843 0.42 ENST00000405188.4
gamma-glutamyltransferase 2
chr17_-_27507377 0.42 ENST00000531253.1
myosin XVIIIA
chr16_-_3306587 0.42 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
Mediterranean fever
chr17_-_34757039 0.42 ENST00000455054.2
ENST00000308078.7
TBC1 domain family, member 3H
TBC1 domain family, member 3C
chr1_-_27286897 0.42 ENST00000320567.5
chromosome 1 open reading frame 172
chr17_-_36348610 0.42 ENST00000339023.4
ENST00000354664.4
TBC1 domain family, member 3
chr7_-_30544405 0.42 ENST00000409390.1
ENST00000409144.1
ENST00000005374.6
ENST00000409436.1
ENST00000275428.4
gamma-glutamylcyclotransferase
chr15_-_20170354 0.42 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr17_-_27507395 0.42 ENST00000354329.4
ENST00000527372.1
myosin XVIIIA
chr17_-_34808047 0.42 ENST00000592614.1
ENST00000591542.1
ENST00000330458.7
ENST00000341264.6
ENST00000592987.1
ENST00000400684.4
TBC1 domain family, member 3G
TBC1 domain family, member 3H
chr1_-_98386543 0.42 ENST00000423006.2
ENST00000370192.3
ENST00000306031.5
dihydropyrimidine dehydrogenase
chr5_+_175288631 0.42 ENST00000509837.1
complexin 2
chr10_+_112257596 0.41 ENST00000369583.3
dual specificity phosphatase 5
chr14_-_100841930 0.41 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
tryptophanyl-tRNA synthetase
chr11_-_1780261 0.41 ENST00000427721.1
RP11-295K3.1
chr19_+_42829702 0.41 ENST00000334370.4
multiple EGF-like-domains 8
chr2_-_219696519 0.41 ENST00000545803.1
ENST00000430489.1
ENST00000392098.3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr19_-_19843900 0.40 ENST00000344099.3
zinc finger protein 14
chr4_+_110481348 0.40 ENST00000394650.4
coiled-coil domain containing 109B
chr22_+_39745930 0.40 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
synaptogyrin 1
chr7_+_2727817 0.40 ENST00000407112.1
archaelysin family metallopeptidase 1
chr4_+_25915896 0.40 ENST00000514384.1
small integral membrane protein 20
chr6_-_41006928 0.40 ENST00000244565.3
unc-5 homolog C (C. elegans)-like
chr10_+_120863587 0.40 ENST00000535029.1
ENST00000361432.2
ENST00000544016.1
family with sequence similarity 45, member A
chr18_-_11908329 0.40 ENST00000344987.7
ENST00000588103.1
ENST00000588191.1
ENST00000317235.7
ENST00000309976.9
ENST00000588186.1
ENST00000589267.1
metallophosphoesterase 1
chr3_+_169684553 0.40 ENST00000337002.4
ENST00000480708.1
SEC62 homolog (S. cerevisiae)
chr4_-_130692631 0.40 ENST00000500092.2
ENST00000509105.1
RP11-519M16.1
chr11_+_66624527 0.40 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr2_-_201828356 0.39 ENST00000234296.2
origin recognition complex, subunit 2
chr6_+_33378738 0.39 ENST00000374512.3
ENST00000374516.3
PHD finger protein 1
chr5_+_57878859 0.39 ENST00000282878.4
RAB3C, member RAS oncogene family
chr3_-_138313161 0.39 ENST00000489254.1
ENST00000474781.1
ENST00000462419.1
ENST00000264982.3
centrosomal protein 70kDa
chr7_+_101460882 0.38 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
cut-like homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
1.0 2.9 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.5 1.5 GO:0036146 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.5 2.9 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.5 1.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 1.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.4 1.1 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.3 1.8 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.3 1.8 GO:0009450 acetate metabolic process(GO:0006083) gamma-aminobutyric acid catabolic process(GO:0009450)
0.3 0.9 GO:0071284 cellular response to lead ion(GO:0071284)
0.3 0.8 GO:1903028 positive regulation of opsonization(GO:1903028)
0.3 2.6 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.2 0.7 GO:0033214 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.2 1.0 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 0.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 1.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.7 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 0.6 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.2 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 1.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.2 0.5 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 1.5 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.4 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 1.2 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.1 0.8 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.5 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.5 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 1.3 GO:0001955 blood vessel maturation(GO:0001955)
0.1 1.4 GO:0042908 xenobiotic transport(GO:0042908)
0.1 1.0 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1 0.5 GO:0007538 primary sex determination(GO:0007538)
0.1 0.8 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.7 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.9 GO:0050893 sensory processing(GO:0050893)
0.1 0.3 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 0.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 1.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.4 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.9 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.4 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.7 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.7 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.3 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.6 GO:0006789 bilirubin conjugation(GO:0006789)
0.1 0.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.6 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.3 GO:0071623 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 0.3 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.3 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.3 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.2 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 1.1 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 1.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 0.6 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.2 GO:0060931 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.1 0.9 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 1.9 GO:0007141 male meiosis I(GO:0007141)
0.1 0.2 GO:1903625 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.2 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.2 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.1 1.3 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 0.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.5 GO:0070836 caveola assembly(GO:0070836)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.4 GO:0007506 gonadal mesoderm development(GO:0007506)
0.1 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.3 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.2 GO:1903215 regulation of kidney size(GO:0035564) positive regulation of protein autoubiquitination(GO:1902499) negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.3 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.4 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.3 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.2 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.8 GO:0006853 carnitine shuttle(GO:0006853)
0.0 2.8 GO:0006301 postreplication repair(GO:0006301)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.2 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.2 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 1.1 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.4 GO:2000781 DNA dealkylation involved in DNA repair(GO:0006307) positive regulation of double-strand break repair(GO:2000781)
0.0 0.3 GO:0002467 germinal center formation(GO:0002467)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 1.5 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 2.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 3.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.7 GO:0006525 arginine metabolic process(GO:0006525)
0.0 0.6 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 3.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.4 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 1.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.6 GO:0036344 platelet morphogenesis(GO:0036344)
0.0 0.0 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.4 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 3.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 2.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:1902951 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.4 GO:0061082 myeloid leukocyte cytokine production(GO:0061082)
0.0 0.2 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.3 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0021539 subthalamus development(GO:0021539)
0.0 0.3 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.1 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:0043651 alpha-linolenic acid metabolic process(GO:0036109) linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0045991 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.4 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0007140 male meiosis(GO:0007140)
0.0 0.8 GO:0048278 vesicle docking(GO:0048278)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 1.5 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.1 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.0 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.0 1.5 GO:0006664 glycolipid metabolic process(GO:0006664) liposaccharide metabolic process(GO:1903509)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 0.4 GO:0071751 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 0.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.5 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 0.7 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 2.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.7 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.0 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.9 GO:0034464 BBSome(GO:0034464)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.1 2.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.0 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:0005713 recombination nodule(GO:0005713)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 2.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 3.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 1.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0032810 sterol response element binding(GO:0032810)
0.3 2.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.3 0.9 GO:0032767 copper-dependent protein binding(GO:0032767)
0.3 2.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 0.9 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.2 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.4 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.4 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.5 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.5 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 1.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.4 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 1.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.3 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 1.4 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 1.0 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.9 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.2 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.7 GO:0043426 MRF binding(GO:0043426)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 1.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.3 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 3.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.2 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 1.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.6 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.4 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 0.2 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.5 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.3 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.6 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 1.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 2.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 6.9 GO:0003823 antigen binding(GO:0003823)
0.0 1.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.7 GO:0031432 titin binding(GO:0031432)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.4 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.0 1.7 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.1 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.9 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0043531 ADP binding(GO:0043531)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 2.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 3.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 3.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 3.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 3.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.7