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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ESRRB_ESRRG

Z-value: 0.71

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Transcription factors associated with ESRRB_ESRRG

Gene Symbol Gene ID Gene Info
ESRRB
ENSG00000119715.10 estrogen related receptor beta
ESRRG
ENSG00000196482.12 estrogen related receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESRRGhg19_v2_chr1_-_217250231_217250349-0.242.6e-01Click!
ESRRBhg19_v2_chr14_+_76776957_76777061-0.019.5e-01Click!

Activity profile of ESRRB_ESRRG motif

Sorted Z-values of ESRRB_ESRRG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_123339343 1.85 ENST00000578202.1
MYLK
myosin light chain kinase
chr3_-_123339418 1.81 ENST00000583087.1
MYLK
myosin light chain kinase
chr4_-_76957214 1.03 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr16_+_56623433 0.77 ENST00000570176.1
MT3
metallothionein 3
chr12_-_111358372 0.76 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr6_-_9933500 0.68 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chrX_+_52927576 0.61 ENST00000416841.2
FAM156B
family with sequence similarity 156, member B
chr4_+_24797085 0.60 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr3_-_42743006 0.59 ENST00000310417.5
HHATL
hedgehog acyltransferase-like
chr6_+_107349392 0.59 ENST00000443043.1
ENST00000405204.2
ENST00000311381.5
C6orf203
chromosome 6 open reading frame 203
chr22_+_30821732 0.58 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr13_-_44361025 0.58 ENST00000261488.6
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr1_+_169077172 0.58 ENST00000499679.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr14_-_58893832 0.58 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr4_-_74864386 0.58 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr22_-_47134077 0.57 ENST00000541677.1
ENST00000216264.8
CERK
ceramide kinase
chr20_-_62130474 0.56 ENST00000217182.3
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr11_-_86666427 0.56 ENST00000531380.1
FZD4
frizzled family receptor 4
chr11_+_86667117 0.56 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr15_-_91475747 0.55 ENST00000330334.3
ENST00000559898.1
ENST00000394272.3
HDDC3
HD domain containing 3
chr5_-_19988339 0.55 ENST00000382275.1
CDH18
cadherin 18, type 2
chr8_-_110346614 0.55 ENST00000239690.4
NUDCD1
NudC domain containing 1
chr16_-_3767506 0.55 ENST00000538171.1
TRAP1
TNF receptor-associated protein 1
chr5_-_87564620 0.54 ENST00000506536.1
ENST00000512429.1
ENST00000514135.1
ENST00000296595.6
ENST00000509387.1
TMEM161B
transmembrane protein 161B
chr6_-_33548006 0.53 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr3_+_113666748 0.53 ENST00000330212.3
ENST00000498275.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr20_+_58179582 0.52 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr5_-_150473127 0.52 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr1_-_200992827 0.52 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr11_-_34379546 0.52 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr22_+_21128167 0.52 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr6_-_33547975 0.52 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr3_-_14166316 0.51 ENST00000396914.3
ENST00000295767.5
CHCHD4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr16_-_3767551 0.51 ENST00000246957.5
TRAP1
TNF receptor-associated protein 1
chr17_+_4981535 0.51 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr22_+_46546494 0.50 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
PPARA
peroxisome proliferator-activated receptor alpha
chr11_+_7618413 0.50 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr18_-_24128496 0.49 ENST00000417602.1
KCTD1
potassium channel tetramerization domain containing 1
chr3_-_49377499 0.49 ENST00000265560.4
USP4
ubiquitin specific peptidase 4 (proto-oncogene)
chr16_-_30537839 0.49 ENST00000380412.5
ZNF768
zinc finger protein 768
chr1_-_23504176 0.49 ENST00000302291.4
LUZP1
leucine zipper protein 1
chr14_-_74226961 0.47 ENST00000286523.5
ENST00000435371.1
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr19_+_45449266 0.42 ENST00000592257.1
APOC2
apolipoprotein C-II
chr2_-_42721110 0.42 ENST00000394973.4
ENST00000306078.1
KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr1_+_169075554 0.42 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_-_190040223 0.42 ENST00000295522.3
CLDN1
claudin 1
chr5_+_34757309 0.41 ENST00000397449.1
RAI14
retinoic acid induced 14
chr12_-_2113583 0.41 ENST00000397173.4
ENST00000280665.6
DCP1B
decapping mRNA 1B
chr3_+_10068095 0.40 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr14_+_22985251 0.40 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr5_-_60140009 0.40 ENST00000505959.1
ELOVL7
ELOVL fatty acid elongase 7
chr20_+_30865429 0.39 ENST00000375712.3
KIF3B
kinesin family member 3B
chr14_-_107114267 0.39 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr7_-_138458781 0.39 ENST00000393054.1
ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr3_-_42845951 0.38 ENST00000418900.2
ENST00000430190.1
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr22_+_32149927 0.38 ENST00000437411.1
ENST00000535622.1
ENST00000536766.1
ENST00000400242.3
ENST00000266091.3
ENST00000400249.2
ENST00000400246.1
ENST00000382105.2
DEPDC5
DEP domain containing 5
chr13_-_111214015 0.38 ENST00000267328.3
RAB20
RAB20, member RAS oncogene family
chr7_-_142232071 0.38 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr10_+_60028818 0.37 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr1_-_144995002 0.37 ENST00000369356.4
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_+_153600869 0.37 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chr9_+_135937365 0.37 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr2_+_220491973 0.36 ENST00000358055.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr2_-_74374995 0.36 ENST00000295326.4
BOLA3
bolA family member 3
chr3_-_156840776 0.36 ENST00000471357.1
LINC00880
long intergenic non-protein coding RNA 880
chr1_-_145075847 0.35 ENST00000530740.1
ENST00000369359.4
PDE4DIP
phosphodiesterase 4D interacting protein
chr3_-_167452262 0.35 ENST00000487947.2
PDCD10
programmed cell death 10
chr7_+_55177416 0.35 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr12_+_6976687 0.35 ENST00000396705.5
TPI1
triosephosphate isomerase 1
chr5_+_218356 0.34 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr12_+_52306113 0.34 ENST00000547400.1
ENST00000550683.1
ENST00000419526.2
ACVRL1
activin A receptor type II-like 1
chr1_+_206858328 0.34 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr1_-_241683001 0.33 ENST00000366560.3
FH
fumarate hydratase
chr11_-_132813566 0.33 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr3_-_42744312 0.33 ENST00000416756.1
ENST00000441594.1
HHATL
hedgehog acyltransferase-like
chr9_-_130966497 0.33 ENST00000393608.1
ENST00000372948.3
CIZ1
CDKN1A interacting zinc finger protein 1
chr19_+_1407517 0.33 ENST00000336761.6
ENST00000233078.4
DAZAP1
DAZ associated protein 1
chr2_+_220363579 0.32 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GMPPA
GDP-mannose pyrophosphorylase A
chr2_-_44223138 0.32 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr2_+_220492116 0.32 ENST00000373760.2
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr20_+_57430162 0.32 ENST00000450130.1
ENST00000349036.3
ENST00000423897.1
GNAS
GNAS complex locus
chr16_-_66952742 0.32 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chr10_+_81107216 0.31 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr20_-_13765526 0.31 ENST00000202816.1
ESF1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr14_+_51026743 0.31 ENST00000358385.6
ENST00000357032.3
ENST00000354525.4
ATL1
atlastin GTPase 1
chr19_+_35629702 0.31 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr7_-_27224842 0.30 ENST00000517402.1
HOXA11
homeobox A11
chr7_-_27224795 0.30 ENST00000006015.3
HOXA11
homeobox A11
chr22_+_31518938 0.30 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr15_+_43809797 0.30 ENST00000399453.1
ENST00000300231.5
MAP1A
microtubule-associated protein 1A
chr16_-_74734742 0.29 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr4_+_36283213 0.29 ENST00000357504.3
DTHD1
death domain containing 1
chr15_+_76352178 0.29 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr13_+_22245522 0.29 ENST00000382353.5
FGF9
fibroblast growth factor 9
chr16_+_2587965 0.29 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr14_-_21492113 0.29 ENST00000554094.1
NDRG2
NDRG family member 2
chr16_+_691792 0.29 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr9_-_117150303 0.28 ENST00000312033.3
AKNA
AT-hook transcription factor
chr15_-_81616446 0.28 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr17_+_43238438 0.28 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr5_-_95768973 0.28 ENST00000311106.3
PCSK1
proprotein convertase subtilisin/kexin type 1
chr17_+_79670386 0.28 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
MRPL12
SLC25A10
SLC25A10
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr11_+_71710648 0.28 ENST00000260049.5
IL18BP
interleukin 18 binding protein
chr16_-_66952779 0.28 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
CDH16
cadherin 16, KSP-cadherin
chr18_-_5544241 0.28 ENST00000341928.2
ENST00000540638.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr17_-_29624343 0.27 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr2_+_89975669 0.27 ENST00000474213.1
IGKV2D-30
immunoglobulin kappa variable 2D-30
chr2_+_220492373 0.27 ENST00000317151.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr20_+_53092123 0.27 ENST00000262593.5
DOK5
docking protein 5
chr3_-_50605077 0.27 ENST00000426034.1
ENST00000441239.1
C3orf18
chromosome 3 open reading frame 18
chr16_+_4674787 0.27 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr16_+_30937213 0.27 ENST00000427128.1
FBXL19
F-box and leucine-rich repeat protein 19
chr3_+_88188254 0.27 ENST00000309495.5
ZNF654
zinc finger protein 654
chr17_-_49198216 0.27 ENST00000262013.7
ENST00000357122.4
SPAG9
sperm associated antigen 9
chr15_+_41913690 0.27 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr19_+_45449228 0.26 ENST00000252490.4
APOC2
apolipoprotein C-II
chr22_-_46644182 0.26 ENST00000404583.1
ENST00000404744.1
CDPF1
cysteine-rich, DPF motif domain containing 1
chr7_+_75027418 0.26 ENST00000447409.2
TRIM73
tripartite motif containing 73
chr21_+_43639211 0.26 ENST00000450121.1
ENST00000398449.3
ENST00000361802.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr19_-_1513188 0.26 ENST00000330475.4
ADAMTSL5
ADAMTS-like 5
chr14_-_21492251 0.26 ENST00000554398.1
NDRG2
NDRG family member 2
chr12_+_54378923 0.26 ENST00000303460.4
HOXC10
homeobox C10
chr2_+_220492287 0.26 ENST00000273063.6
ENST00000373762.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr16_+_11038345 0.25 ENST00000409790.1
CLEC16A
C-type lectin domain family 16, member A
chr19_+_16771936 0.25 ENST00000187762.2
ENST00000599479.1
TMEM38A
transmembrane protein 38A
chr16_+_2588012 0.25 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr2_-_209028300 0.25 ENST00000304502.4
CRYGA
crystallin, gamma A
chr8_-_135522425 0.25 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr9_-_35685452 0.25 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr6_+_53948328 0.25 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr1_-_241520385 0.24 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr19_-_55574538 0.24 ENST00000415061.3
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr11_-_72463421 0.24 ENST00000393609.3
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr3_-_167452298 0.24 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10
programmed cell death 10
chr22_+_30115986 0.24 ENST00000216144.3
CABP7
calcium binding protein 7
chr15_-_41694640 0.24 ENST00000558719.1
ENST00000260361.4
ENST00000560978.1
NDUFAF1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
chr8_+_145149930 0.24 ENST00000318911.4
CYC1
cytochrome c-1
chr16_+_11038403 0.24 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A
chr1_+_165600436 0.24 ENST00000367888.4
ENST00000367885.1
ENST00000367884.2
MGST3
microsomal glutathione S-transferase 3
chr10_+_71078595 0.24 ENST00000359426.6
HK1
hexokinase 1
chr7_+_39663485 0.24 ENST00000436179.1
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr6_-_119399895 0.23 ENST00000338891.7
FAM184A
family with sequence similarity 184, member A
chr1_+_68150744 0.23 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr4_-_71705082 0.23 ENST00000439371.1
ENST00000499044.2
GRSF1
G-rich RNA sequence binding factor 1
chrX_-_108868390 0.23 ENST00000372101.2
KCNE1L
KCNE1-like
chr20_+_58152524 0.23 ENST00000359926.3
PHACTR3
phosphatase and actin regulator 3
chr14_-_105262016 0.23 ENST00000407796.2
AKT1
v-akt murine thymoma viral oncogene homolog 1
chr7_-_140624499 0.23 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr14_-_105262055 0.23 ENST00000349310.3
AKT1
v-akt murine thymoma viral oncogene homolog 1
chr11_+_34938119 0.22 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
PDHX
pyruvate dehydrogenase complex, component X
chr3_-_49377446 0.22 ENST00000351842.4
ENST00000416417.1
ENST00000415188.1
USP4
ubiquitin specific peptidase 4 (proto-oncogene)
chr1_-_241520525 0.22 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr7_-_72437484 0.22 ENST00000395244.1
TRIM74
tripartite motif containing 74
chr12_-_53320245 0.22 ENST00000552150.1
KRT8
keratin 8
chr10_-_81320151 0.22 ENST00000372325.2
ENST00000372327.5
ENST00000417041.1
SFTPA2
surfactant protein A2
chr3_-_49158312 0.22 ENST00000398892.3
ENST00000453664.1
ENST00000398888.2
USP19
ubiquitin specific peptidase 19
chr3_-_167813132 0.22 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr11_-_3862206 0.22 ENST00000351018.4
RHOG
ras homolog family member G
chr16_+_4674814 0.22 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr15_-_83621435 0.21 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2
homer homolog 2 (Drosophila)
chr2_-_97304009 0.21 ENST00000431828.1
ENST00000435669.1
ENST00000440133.1
ENST00000448075.1
KANSL3
KAT8 regulatory NSL complex subunit 3
chr16_-_30538079 0.21 ENST00000562803.1
ZNF768
zinc finger protein 768
chr19_+_2249308 0.21 ENST00000592877.1
ENST00000221496.4
AMH
anti-Mullerian hormone
chr1_+_161195781 0.21 ENST00000367988.3
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr10_-_94003003 0.21 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr7_-_99381884 0.21 ENST00000336411.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr1_+_155179012 0.21 ENST00000609421.1
MTX1
metaxin 1
chr16_-_74734672 0.21 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr19_-_36643329 0.21 ENST00000589154.1
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr9_-_117150243 0.21 ENST00000374088.3
AKNA
AT-hook transcription factor
chr3_+_16306691 0.20 ENST00000285083.5
ENST00000605932.1
ENST00000435829.2
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr3_-_179322436 0.20 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr8_-_125551278 0.20 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TATDN1
TatD DNase domain containing 1
chrX_-_46187069 0.20 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr14_-_31889782 0.20 ENST00000543095.2
HEATR5A
HEAT repeat containing 5A
chr3_+_39149298 0.20 ENST00000440121.1
TTC21A
tetratricopeptide repeat domain 21A
chr17_+_38975358 0.20 ENST00000436612.1
ENST00000301665.3
TMEM99
transmembrane protein 99
chr8_+_12809093 0.20 ENST00000528753.2
KIAA1456
KIAA1456
chr8_-_131028641 0.20 ENST00000523509.1
FAM49B
family with sequence similarity 49, member B
chr3_+_39149145 0.20 ENST00000301819.6
ENST00000431162.2
TTC21A
tetratricopeptide repeat domain 21A
chr12_+_6644443 0.20 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr3_+_16306837 0.20 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr11_+_66624527 0.19 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr8_-_131028660 0.19 ENST00000401979.2
ENST00000517654.1
ENST00000522361.1
ENST00000518167.1
FAM49B
family with sequence similarity 49, member B
chr6_+_31916733 0.19 ENST00000483004.1
CFB
complement factor B
chr2_-_97304105 0.19 ENST00000599854.1
ENST00000441706.2
KANSL3
KAT8 regulatory NSL complex subunit 3
chr11_+_75428857 0.19 ENST00000198801.5
MOGAT2
monoacylglycerol O-acyltransferase 2
chr3_-_179322416 0.19 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chrX_+_49832231 0.19 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr17_+_74372662 0.19 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr5_-_65017921 0.19 ENST00000381007.4
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr4_-_122872909 0.19 ENST00000379645.3
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr19_+_14138960 0.18 ENST00000431365.2
ENST00000585987.1
RLN3
relaxin 3
chr10_+_99185917 0.18 ENST00000334828.5
PGAM1
phosphoglycerate mutase 1 (brain)
chr1_+_46640750 0.18 ENST00000372003.1
TSPAN1
tetraspanin 1
chr15_-_42783303 0.18 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr6_+_44310376 0.18 ENST00000515220.1
ENST00000323108.8
SPATS1
spermatogenesis associated, serine-rich 1
chr13_-_41345277 0.18 ENST00000323563.6
MRPS31
mitochondrial ribosomal protein S31
chr7_-_131241361 0.18 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL
podocalyxin-like
chr19_+_589893 0.18 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ESRRB_ESRRG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.0 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 0.9 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.3 1.1 GO:0009386 translational attenuation(GO:0009386)
0.3 0.8 GO:2000374 cadmium ion homeostasis(GO:0055073) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
0.2 1.0 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.7 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.2 0.5 GO:0021503 neural fold bending(GO:0021503)
0.1 0.4 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 0.4 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.5 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.5 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 0.3 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.5 GO:1903719 positive regulation of endodeoxyribonuclease activity(GO:0032079) regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.3 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.5 GO:0060356 leucine import(GO:0060356)
0.1 1.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.3 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.6 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.3 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.3 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.1 GO:0019046 release from viral latency(GO:0019046)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.3 GO:1903273 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.1 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.1 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.2 GO:0009822 alkaloid catabolic process(GO:0009822) calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.6 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.7 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:1903998 response to isolation stress(GO:0035900) regulation of eating behavior(GO:1903998)
0.0 0.3 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0002519 natural killer cell tolerance induction(GO:0002519)
0.0 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.6 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.4 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.1 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.2 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.4 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.4 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.7 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:2000035 positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0035565 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0051105 regulation of DNA ligation(GO:0051105)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.0 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.1 GO:2001287 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0018016 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.0 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.5 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.0 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.0 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:1990034 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.0 GO:0052314 isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314)
0.0 0.3 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.0 GO:0034334 adherens junction maintenance(GO:0034334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.6 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.4 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.3 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.2 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.1 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.3 GO:0070470 plasma membrane respiratory chain(GO:0070470)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 3.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.7 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 1.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.7 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.2 1.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.7 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.8 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.3 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.3 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.3 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.6 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.8 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 1.0 GO:0030955 potassium ion binding(GO:0030955)
0.0 1.0 GO:0051400 BH domain binding(GO:0051400)
0.0 0.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.5 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.4 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.0 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0022821 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.0 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.0 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 ST ADRENERGIC Adrenergic Pathway
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.5 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 1.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.0 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation