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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for EVX2
Z-value: 0.32
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Transcription factors associated with EVX2
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_-_55562479 Show fit | 0.64 |
ENST00000564609.1
|
RAB27A, member RAS oncogene family |
|
| chr15_-_55563072 Show fit | 0.60 |
ENST00000567380.1
ENST00000565972.1 ENST00000569493.1 |
RAB27A, member RAS oncogene family |
|
| chr15_-_55562582 Show fit | 0.59 |
ENST00000396307.2
|
RAB27A, member RAS oncogene family |
|
| chr3_+_111717511 Show fit | 0.44 |
ENST00000478951.1
ENST00000393917.2 |
transgelin 3 |
|
| chr3_+_111717600 Show fit | 0.43 |
ENST00000273368.4
|
transgelin 3 |
|
| chr18_-_33709268 Show fit | 0.41 |
ENST00000269187.5
ENST00000590986.1 ENST00000440549.2 |
solute carrier family 39 (zinc transporter), member 6 |
|
| chr3_+_111718036 Show fit | 0.39 |
ENST00000455401.2
|
transgelin 3 |
|
| chr4_+_144354644 Show fit | 0.36 |
ENST00000512843.1
|
GRB2-associated binding protein 1 |
|
| chr6_-_62996066 Show fit | 0.31 |
ENST00000281156.4
|
KH domain containing, RNA binding, signal transduction associated 2 |
|
| chr20_-_50419055 Show fit | 0.26 |
ENST00000217086.4
|
spalt-like transcription factor 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of EVX2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.8 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.0 | 0.7 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.5 | GO:0014894 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.0 | 0.4 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.0 | 0.4 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.0 | 0.1 | GO:0036058 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 0.0 | 0.1 | GO:0044771 | meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.1 | 0.5 | GO:0014802 | terminal cisterna(GO:0014802) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 0.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.3 | GO:0008143 | poly(A) binding(GO:0008143) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.4 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |