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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for EZH2

Z-value: 1.13

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Transcription factors associated with EZH2

Gene Symbol Gene ID Gene Info
ENSG00000106462.6 enhancer of zeste 2 polycomb repressive complex 2 subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EZH2hg19_v2_chr7_-_148581251_1485813470.481.6e-02Click!

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_72441315 8.68 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
dachshund homolog 1 (Drosophila)
chr4_-_16900242 6.40 ENST00000502640.1
ENST00000506732.1
LIM domain binding 2
chr4_+_156588249 6.39 ENST00000393832.3
guanylate cyclase 1, soluble, alpha 3
chr4_-_16900184 5.86 ENST00000515064.1
LIM domain binding 2
chr4_-_16900217 5.67 ENST00000441778.2
LIM domain binding 2
chr4_-_16900410 4.71 ENST00000304523.5
LIM domain binding 2
chr4_+_156588115 4.70 ENST00000455639.2
guanylate cyclase 1, soluble, alpha 3
chr5_+_175298573 3.74 ENST00000512824.1
complexin 2
chr13_-_72440901 3.38 ENST00000359684.2
dachshund homolog 1 (Drosophila)
chr14_-_54423529 3.00 ENST00000245451.4
ENST00000559087.1
bone morphogenetic protein 4
chr6_+_142623063 2.41 ENST00000296932.8
ENST00000367609.3
G protein-coupled receptor 126
chr4_+_156587979 2.40 ENST00000511507.1
guanylate cyclase 1, soluble, alpha 3
chr4_+_156588350 2.34 ENST00000296518.7
guanylate cyclase 1, soluble, alpha 3
chr1_+_61869748 2.33 ENST00000357977.5
nuclear factor I/A
chr8_+_97506033 2.32 ENST00000518385.1
syndecan 2
chr10_-_116444371 2.26 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr4_-_101439148 2.24 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
endomucin
chr4_-_101439242 2.09 ENST00000296420.4
endomucin
chr5_+_175298674 1.99 ENST00000514150.1
complexin 2
chr4_-_70626314 1.98 ENST00000510821.1
sulfotransferase family, cytosolic, 1B, member 1
chr1_+_47489240 1.82 ENST00000371901.3
cytochrome P450, family 4, subfamily X, polypeptide 1
chr9_+_133971863 1.75 ENST00000372309.3
allograft inflammatory factor 1-like
chr4_+_126237554 1.70 ENST00000394329.3
FAT atypical cadherin 4
chr9_+_133971909 1.65 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
allograft inflammatory factor 1-like
chr19_+_51152702 1.64 ENST00000425202.1
chromosome 19 open reading frame 81
chr6_+_53659746 1.62 ENST00000370888.1
leucine rich repeat containing 1
chr9_-_16727978 1.57 ENST00000418777.1
ENST00000468187.2
basonuclin 2
chr7_+_150688166 1.57 ENST00000461406.1
nitric oxide synthase 3 (endothelial cell)
chr9_-_107690420 1.53 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr7_+_102553430 1.50 ENST00000339431.4
ENST00000249377.4
leucine rich repeat containing 17
chr5_+_175298487 1.48 ENST00000393745.3
complexin 2
chr12_+_79258444 1.43 ENST00000261205.4
synaptotagmin I
chr12_+_79258547 1.43 ENST00000457153.2
synaptotagmin I
chr9_-_14314566 1.42 ENST00000397579.2
nuclear factor I/B
chr3_+_193853927 1.37 ENST00000232424.3
hes family bHLH transcription factor 1
chr6_-_10415218 1.36 ENST00000466073.1
ENST00000498450.1
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_-_6420565 1.36 ENST00000338312.6
angiopoietin 2
chr1_+_61330931 1.35 ENST00000371191.1
nuclear factor I/A
chrX_-_19688475 1.30 ENST00000541422.1
SH3-domain kinase binding protein 1
chr7_-_38671098 1.30 ENST00000356264.2
amphiphysin
chr4_-_159094194 1.29 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr1_-_46598371 1.28 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr2_+_210288760 1.26 ENST00000199940.6
microtubule-associated protein 2
chr1_+_164528866 1.25 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr9_-_16728161 1.25 ENST00000603713.1
ENST00000603313.1
basonuclin 2
chr1_+_61542922 1.23 ENST00000407417.3
nuclear factor I/A
chr12_+_93965451 1.23 ENST00000548537.1
suppressor of cytokine signaling 2
chr14_+_23846328 1.23 ENST00000382809.2
CKLF-like MARVEL transmembrane domain containing 5
chr9_-_14314518 1.23 ENST00000397581.2
nuclear factor I/B
chr12_+_93965609 1.22 ENST00000549887.1
ENST00000551556.1
suppressor of cytokine signaling 2
chr5_-_111093340 1.18 ENST00000508870.1
neuronal regeneration related protein
chrX_+_28605516 1.16 ENST00000378993.1
interleukin 1 receptor accessory protein-like 1
chr4_+_30721968 1.16 ENST00000361762.2
protocadherin 7
chr11_-_33891362 1.14 ENST00000395833.3
LIM domain only 2 (rhombotin-like 1)
chr5_-_111092873 1.13 ENST00000509025.1
ENST00000515855.1
neuronal regeneration related protein
chr11_-_44331679 1.11 ENST00000329255.3
ALX homeobox 4
chr19_+_45973120 1.10 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr1_+_214161272 1.10 ENST00000498508.2
ENST00000366958.4
prospero homeobox 1
chr10_+_94590910 1.07 ENST00000371547.4
exocyst complex component 6
chr8_-_4852494 1.07 ENST00000520002.1
ENST00000602557.1
CUB and Sushi multiple domains 1
chr1_-_46598284 1.06 ENST00000423209.1
ENST00000262741.5
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr2_-_188312971 1.05 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
calcitonin receptor-like
chr2_+_11864458 1.04 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
lipin 1
chr5_+_121647877 1.03 ENST00000514497.2
ENST00000261367.7
synuclein, alpha interacting protein
chr8_-_6420759 1.03 ENST00000523120.1
angiopoietin 2
chr2_+_28615669 1.01 ENST00000379619.1
ENST00000264716.4
FOS-like antigen 2
chr2_+_173686303 1.01 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr3_-_112360116 1.01 ENST00000206423.3
ENST00000439685.2
coiled-coil domain containing 80
chr17_+_61562201 1.00 ENST00000290863.6
ENST00000413513.3
ENST00000421982.2
angiotensin I converting enzyme
chr17_+_7387677 0.99 ENST00000322644.6
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr8_-_4852218 0.99 ENST00000400186.3
ENST00000602723.1
CUB and Sushi multiple domains 1
chr8_-_6420777 0.99 ENST00000415216.1
angiopoietin 2
chr4_+_123747834 0.98 ENST00000264498.3
fibroblast growth factor 2 (basic)
chr2_+_33172221 0.98 ENST00000354476.3
latent transforming growth factor beta binding protein 1
chr9_-_16870704 0.96 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
basonuclin 2
chr5_-_35195338 0.94 ENST00000509839.1
prolactin receptor
chr4_+_74735102 0.94 ENST00000395761.3
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr10_+_30722866 0.94 ENST00000263056.1
mitogen-activated protein kinase kinase kinase 8
chr14_-_21270995 0.89 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
ribonuclease, RNase A family, 1 (pancreatic)
chr17_+_61562178 0.89 ENST00000490216.2
angiotensin I converting enzyme
chr10_-_33623564 0.89 ENST00000374875.1
ENST00000374822.4
neuropilin 1
chr11_-_34533257 0.87 ENST00000312319.2
E74-like factor 5 (ets domain transcription factor)
chrX_-_24665208 0.87 ENST00000356768.4
phosphate cytidylyltransferase 1, choline, beta
chr4_+_144257915 0.86 ENST00000262995.4
GRB2-associated binding protein 1
chr2_+_169926047 0.86 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr18_-_52969844 0.86 ENST00000561831.3
transcription factor 4
chr5_-_88179302 0.85 ENST00000504921.2
myocyte enhancer factor 2C
chr17_-_40575535 0.84 ENST00000357037.5
polymerase I and transcript release factor
chr9_+_75766763 0.83 ENST00000456643.1
ENST00000415424.1
annexin A1
chr17_+_61571746 0.82 ENST00000579409.1
angiotensin I converting enzyme
chr16_+_30406721 0.82 ENST00000320159.2
zinc finger protein 48
chr5_+_140571902 0.82 ENST00000239446.4
protocadherin beta 10
chr14_-_23285069 0.81 ENST00000554758.1
ENST00000397528.4
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr8_-_117043 0.80 ENST00000320901.3
olfactory receptor, family 4, subfamily F, member 21
chr1_+_367640 0.80 ENST00000426406.1
olfactory receptor, family 4, subfamily F, member 29
chr18_-_53177984 0.80 ENST00000543082.1
transcription factor 4
chr3_-_197300194 0.78 ENST00000358186.2
ENST00000431056.1
3-hydroxybutyrate dehydrogenase, type 1
chr14_-_23285011 0.77 ENST00000397532.3
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_+_33359687 0.76 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chrX_+_24711997 0.76 ENST00000379068.3
ENST00000379059.3
polymerase (DNA directed), alpha 1, catalytic subunit
chr6_-_110500905 0.76 ENST00000392587.2
WAS protein family, member 1
chr6_-_110501200 0.75 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WAS protein family, member 1
chr9_+_2158443 0.74 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_81205373 0.72 ENST00000372336.3
zinc finger, CCHC domain containing 24
chr17_-_38938786 0.72 ENST00000301656.3
keratin 27
chr16_-_89785777 0.72 ENST00000561976.1
VPS9 domain containing 1
chr3_-_47324242 0.71 ENST00000456548.1
ENST00000432493.1
ENST00000335044.2
ENST00000444589.2
kinesin family member 9
chr8_-_6420930 0.70 ENST00000325203.5
angiopoietin 2
chr15_-_37390482 0.70 ENST00000559085.1
ENST00000397624.3
Meis homeobox 2
chr3_-_129035120 0.68 ENST00000333762.4
H1 histone family, member X
chr4_+_134070439 0.67 ENST00000264360.5
protocadherin 10
chr2_-_220435963 0.67 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
obscurin-like 1
chr3_+_141103634 0.66 ENST00000507722.1
zinc finger and BTB domain containing 38
chr12_+_100660909 0.66 ENST00000549687.1
SCY1-like 2 (S. cerevisiae)
chr7_-_86688990 0.65 ENST00000450689.2
KIAA1324-like
chr21_-_40032581 0.65 ENST00000398919.2
v-ets avian erythroblastosis virus E26 oncogene homolog
chr11_+_114168773 0.65 ENST00000542647.1
ENST00000545255.1
nicotinamide N-methyltransferase
chr19_-_12992244 0.65 ENST00000538460.1
deoxyribonuclease II, lysosomal
chr1_-_151345159 0.65 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
selenium binding protein 1
chr6_-_75915757 0.65 ENST00000322507.8
collagen, type XII, alpha 1
chr12_-_15038779 0.65 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr18_-_52989525 0.65 ENST00000457482.3
transcription factor 4
chr17_+_36584662 0.65 ENST00000431231.2
ENST00000437668.3
Rho GTPase activating protein 23
chr5_-_141249154 0.65 ENST00000357517.5
ENST00000536585.1
protocadherin 1
chr6_-_31697255 0.64 ENST00000436437.1
dimethylarginine dimethylaminohydrolase 2
chr11_+_114128522 0.63 ENST00000535401.1
nicotinamide N-methyltransferase
chr16_+_30662050 0.61 ENST00000568754.1
proline rich 14
chrX_-_70474499 0.60 ENST00000353904.2
zinc finger, MYM-type 3
chr6_+_25279651 0.60 ENST00000329474.6
leucine rich repeat containing 16A
chr14_+_22615942 0.59 ENST00000390457.2
T cell receptor alpha variable 27
chr16_+_20775358 0.59 ENST00000440284.2
acyl-CoA synthetase medium-chain family member 3
chr2_+_228678550 0.59 ENST00000409189.3
ENST00000358813.4
chemokine (C-C motif) ligand 20
chr14_+_23846210 0.59 ENST00000339180.4
ENST00000342473.4
ENST00000397227.3
ENST00000555731.1
CKLF-like MARVEL transmembrane domain containing 5
chr19_-_49149553 0.58 ENST00000084798.4
carbonic anhydrase XI
chr8_+_21916680 0.58 ENST00000358242.3
ENST00000415253.1
dematin actin binding protein
chr8_-_93107443 0.58 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_-_7125770 0.58 ENST00000261407.4
lysophosphatidylcholine acyltransferase 3
chr14_+_22985251 0.57 ENST00000390510.1
T cell receptor alpha joining 27
chr6_+_86159821 0.57 ENST00000369651.3
5'-nucleotidase, ecto (CD73)
chrX_-_45060135 0.57 ENST00000398000.2
ENST00000377934.4
chromosome X open reading frame 36
chr8_+_70378852 0.57 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
sulfatase 1
chr8_+_21916710 0.57 ENST00000523266.1
ENST00000519907.1
dematin actin binding protein
chr2_+_33359646 0.56 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr3_-_99569821 0.56 ENST00000487087.1
filamin A interacting protein 1-like
chr11_+_64004888 0.56 ENST00000541681.1
vascular endothelial growth factor B
chr21_+_17792672 0.56 ENST00000602620.1
long intergenic non-protein coding RNA 478
chr11_-_118095718 0.55 ENST00000526620.1
adhesion molecule, interacts with CXADR antigen 1
chr14_+_76071805 0.55 ENST00000539311.1
feline leukemia virus subgroup C cellular receptor family, member 2
chr1_+_66458072 0.54 ENST00000423207.2
phosphodiesterase 4B, cAMP-specific
chr20_-_23066953 0.54 ENST00000246006.4
CD93 molecule
chr7_-_22233442 0.54 ENST00000401957.2
Rap guanine nucleotide exchange factor (GEF) 5
chr8_+_11666649 0.53 ENST00000528643.1
ENST00000525777.1
farnesyl-diphosphate farnesyltransferase 1
chr15_+_59903975 0.53 ENST00000560585.1
ENST00000396065.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr6_-_131277510 0.53 ENST00000525193.1
ENST00000527659.1
erythrocyte membrane protein band 4.1-like 2
chr7_-_120498357 0.53 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr12_-_71031185 0.52 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
protein tyrosine phosphatase, receptor type, B
chr14_+_24590560 0.52 ENST00000558325.1
RP11-468E2.6
chr2_+_63277927 0.51 ENST00000282549.2
orthodenticle homeobox 1
chr12_-_91576561 0.50 ENST00000547568.2
ENST00000552962.1
decorin
chr5_+_140749803 0.50 ENST00000576222.1
protocadherin gamma subfamily B, 3
chr20_+_62669472 0.50 ENST00000463337.1
ENST00000358393.1
long intergenic non-protein coding RNA 176
chr2_-_220436248 0.50 ENST00000265318.4
obscurin-like 1
chr9_+_130860583 0.49 ENST00000373064.5
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr6_+_32146131 0.49 ENST00000375094.3
ring finger protein 5, E3 ubiquitin protein ligase
chr17_-_63822563 0.49 ENST00000317442.8
centrosomal protein 112kDa
chr1_-_155112883 0.49 ENST00000368399.1
ENST00000368400.4
ENST00000341298.3
dolichyl-phosphate mannosyltransferase polypeptide 3
chrX_-_62974941 0.49 ENST00000374872.1
ENST00000253401.6
ENST00000374870.4
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr9_+_130860810 0.49 ENST00000433501.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr11_-_100999775 0.49 ENST00000263463.5
progesterone receptor
chr1_-_68698197 0.48 ENST00000370973.2
ENST00000370971.1
wntless Wnt ligand secretion mediator
chr17_+_38599693 0.48 ENST00000542955.1
ENST00000269593.4
insulin-like growth factor binding protein 4
chr1_-_110933663 0.47 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
solute carrier family 16, member 4
chr1_-_182361327 0.47 ENST00000331872.6
ENST00000311223.5
glutamate-ammonia ligase
chr16_+_69221028 0.47 ENST00000336278.4
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr5_+_175223313 0.47 ENST00000359546.4
complexin 2
chr13_-_29069232 0.46 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
fms-related tyrosine kinase 1
chr1_-_110933611 0.46 ENST00000472422.2
ENST00000437429.2
solute carrier family 16, member 4
chr1_-_153599426 0.46 ENST00000392622.1
S100 calcium binding protein A13
chr6_-_167571817 0.46 ENST00000366834.1
G protein-coupled receptor 31
chr1_-_94586651 0.46 ENST00000535735.1
ENST00000370225.3
ATP-binding cassette, sub-family A (ABC1), member 4
chr11_+_118401899 0.46 ENST00000528373.1
ENST00000544878.1
ENST00000354284.4
ENST00000533137.1
ENST00000532762.1
ENST00000526973.1
ENST00000354064.7
ENST00000533102.1
ENST00000313236.5
ENST00000527267.1
ENST00000524725.1
ENST00000533689.1
transmembrane protein 25
chrX_-_19002696 0.45 ENST00000379942.4
phosphorylase kinase, alpha 2 (liver)
chr3_+_100328433 0.45 ENST00000273352.3
G protein-coupled receptor 128
chr6_+_24495067 0.45 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr5_-_88178964 0.45 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
myocyte enhancer factor 2C
chr18_+_9334755 0.45 ENST00000262120.5
twisted gastrulation BMP signaling modulator 1
chr21_+_47706537 0.45 ENST00000397691.1
ybeY metallopeptidase (putative)
chr5_-_35230434 0.45 ENST00000504500.1
prolactin receptor
chr8_-_101321584 0.45 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr19_-_15235906 0.44 ENST00000600984.1
ilvB (bacterial acetolactate synthase)-like
chr3_-_195538760 0.44 ENST00000475231.1
mucin 4, cell surface associated
chr12_+_58087901 0.44 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr8_+_1993152 0.44 ENST00000262113.4
myomesin 2
chr11_-_118095801 0.44 ENST00000356289.5
adhesion molecule, interacts with CXADR antigen 1
chr1_-_85870177 0.44 ENST00000542148.1
dimethylarginine dimethylaminohydrolase 1
chrX_-_48815633 0.44 ENST00000428668.2
OTU domain containing 5
chr15_+_81293254 0.43 ENST00000267984.2
mesoderm development candidate 1
chr8_-_4851937 0.43 ENST00000537824.1
ENST00000542608.1
ENST00000539096.1
CUB and Sushi multiple domains 1
chr17_+_67498538 0.43 ENST00000589647.1
mitogen-activated protein kinase kinase 6
chr20_-_33732952 0.43 ENST00000541621.1
ER degradation enhancer, mannosidase alpha-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 15.8 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
1.5 12.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.0 4.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
1.0 3.0 GO:2000006 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
1.0 2.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.7 23.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.7 2.7 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.5 1.6 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740) smooth muscle hyperplasia(GO:0014806)
0.5 1.4 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.4 1.7 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4 1.7 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.4 1.2 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.4 1.5 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.4 2.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 1.4 GO:0003409 optic cup structural organization(GO:0003409)
0.3 1.0 GO:0001172 transcription, RNA-templated(GO:0001172)
0.3 0.9 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.3 7.7 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.3 1.7 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.3 0.8 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.2 1.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 2.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 1.5 GO:0048539 bone marrow development(GO:0048539)
0.2 1.5 GO:0008218 bioluminescence(GO:0008218)
0.2 0.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.8 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 0.6 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.2 0.8 GO:0006272 leading strand elongation(GO:0006272)
0.2 0.6 GO:0070666 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.2 0.9 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 0.5 GO:0007497 posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.2 4.0 GO:0072189 ureter development(GO:0072189)
0.2 1.0 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.2 0.3 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.2 0.8 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 1.7 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.9 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.6 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.1 0.4 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.0 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.4 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 2.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.4 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 2.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 3.5 GO:0043586 tongue development(GO:0043586)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.4 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.5 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.4 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.3 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.1 0.7 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.1 0.4 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 0.2 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.3 GO:2000777 endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.3 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.6 GO:0009450 acetate metabolic process(GO:0006083) gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 1.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.5 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 1.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.4 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.7 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.2 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.5 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 2.6 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 1.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 1.2 GO:0015866 ADP transport(GO:0015866)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.4 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 1.1 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.1 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 0.4 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.3 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.1 GO:0001810 regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
0.1 0.3 GO:1903336 positive regulation of protein autoubiquitination(GO:1902499) regulation of late endosome to lysosome transport(GO:1902822) negative regulation of protein targeting to mitochondrion(GO:1903215) negative regulation of vacuolar transport(GO:1903336)
0.1 0.4 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.1 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.5 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 1.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.4 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.3 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.1 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.1 0.3 GO:1903758 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.5 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.1 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 1.2 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0002551 mast cell chemotaxis(GO:0002551)
0.0 1.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 1.3 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.3 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 1.2 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.9 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0071874 axon midline choice point recognition(GO:0016199) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 1.2 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.0 0.3 GO:0071651 mature ribosome assembly(GO:0042256) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.5 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.0 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.6 GO:0045008 depyrimidination(GO:0045008)
0.0 0.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 1.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.2 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.8 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:2001181 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 1.1 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.2 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:1990834 response to odorant(GO:1990834)
0.0 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 1.0 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.4 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.5 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:2001191 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of dendritic cell apoptotic process(GO:2000669) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.1 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.6 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.0 GO:0060221 retinal rod cell differentiation(GO:0060221) positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of receptor clustering(GO:1903911) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.0 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.5 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.5 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.5 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.1 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.3 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0060355 regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.4 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 0.1 GO:0032490 detection of molecule of bacterial origin(GO:0032490)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 1.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.0 GO:0019086 late viral transcription(GO:0019086)
0.0 0.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.0 GO:0045792 negative regulation of cell size(GO:0045792)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.7 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.6 16.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.6 2.9 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3 1.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 1.2 GO:1990393 3M complex(GO:1990393)
0.2 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.6 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.8 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 2.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.1 0.6 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.3 GO:0097447 dendritic tree(GO:0097447)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 2.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 0.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 2.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.4 GO:0044308 axonal spine(GO:0044308)
0.1 37.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.8 GO:0097443 sorting endosome(GO:0097443)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 1.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.9 GO:0008091 spectrin(GO:0008091)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.0 GO:0097386 glial cell projection(GO:0097386)
0.0 1.0 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 2.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.6 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 2.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0042641 actomyosin(GO:0042641)
0.0 1.9 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.7 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.9 GO:0005795 Golgi stack(GO:0005795)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 22.6 GO:0030274 LIM domain binding(GO:0030274)
0.7 12.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.6 16.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.5 1.5 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.5 2.9 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 2.3 GO:0050436 microfibril binding(GO:0050436)
0.5 2.7 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.4 2.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 1.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 1.0 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.3 1.3 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.3 1.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.3 7.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 0.8 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 1.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 2.8 GO:0039706 co-receptor binding(GO:0039706)
0.2 1.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.8 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 2.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 0.5 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 2.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 0.5 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 1.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.5 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.8 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.5 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.9 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.4 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 1.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.3 GO:0047977 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.1 0.9 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.3 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.3 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 2.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.6 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 2.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.9 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.6 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 1.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.5 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 1.5 GO:0070330 aromatase activity(GO:0070330)
0.1 0.9 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 1.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.6 GO:0008430 selenium binding(GO:0008430)
0.1 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.6 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 0.3 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.5 GO:0042731 PH domain binding(GO:0042731)
0.1 4.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0016624 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 7.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0005372 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.8 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.0 GO:0032408 purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701) MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 3.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 6.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 3.4 PID BMP PATHWAY BMP receptor signaling
0.0 2.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.1 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.7 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 2.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 2.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 5.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 4.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 4.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 2.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 1.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.0 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins