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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FIGLA

Z-value: 0.76

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Transcription factors associated with FIGLA

Gene Symbol Gene ID Gene Info
FIGLA
ENSG00000183733.6 folliculogenesis specific bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FIGLAhg19_v2_chr2_-_71017775_71017775-0.281.8e-01Click!

Activity profile of FIGLA motif

Sorted Z-values of FIGLA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_39382900 20.18 ENST00000377721.3
ENST00000455970.2
KRTAP9-2
keratin associated protein 9-2
chr17_+_39394250 5.56 ENST00000254072.6
KRTAP9-8
keratin associated protein 9-8
chr1_+_61542922 2.25 ENST00000407417.3
NFIA
nuclear factor I/A
chr7_-_120497178 2.02 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr7_-_11871815 1.92 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr8_-_80993010 1.86 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr11_-_33913708 1.75 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr5_+_68788594 1.74 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chr7_+_12727250 1.65 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr9_+_90112767 1.33 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr17_+_68165657 1.29 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr8_-_93029865 1.25 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr14_-_92414055 1.16 ENST00000342058.4
FBLN5
fibulin 5
chr12_+_79258444 1.15 ENST00000261205.4
SYT1
synaptotagmin I
chr4_-_90757364 1.13 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr12_+_79258547 1.12 ENST00000457153.2
SYT1
synaptotagmin I
chr2_+_46524537 1.07 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr22_-_37882395 1.06 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr10_-_33625154 1.05 ENST00000265371.4
NRP1
neuropilin 1
chr14_-_92413353 1.04 ENST00000556154.1
FBLN5
fibulin 5
chr16_-_46864955 1.04 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chr4_+_6271558 0.98 ENST00000503569.1
ENST00000226760.1
WFS1
Wolfram syndrome 1 (wolframin)
chr1_+_66258846 0.98 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr8_-_81083731 0.97 ENST00000379096.5
TPD52
tumor protein D52
chr10_+_94608245 0.91 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr11_-_124632179 0.89 ENST00000278927.5
ENST00000442070.2
ENST00000444566.1
ENST00000435477.1
ESAM
endothelial cell adhesion molecule
chr11_-_66115032 0.89 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr1_+_6615241 0.87 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1
taste receptor, type 1, member 1
chr3_-_128294929 0.84 ENST00000356020.2
C3orf27
chromosome 3 open reading frame 27
chr5_+_139027877 0.80 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr3_-_49170405 0.79 ENST00000305544.4
ENST00000494831.1
LAMB2
laminin, beta 2 (laminin S)
chr12_+_32655048 0.78 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr16_+_4845379 0.76 ENST00000588606.1
ENST00000586005.1
SMIM22
small integral membrane protein 22
chr6_-_41888843 0.75 ENST00000434077.1
ENST00000409312.1
MED20
mediator complex subunit 20
chr6_+_155537771 0.73 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr17_-_71088797 0.71 ENST00000580557.1
ENST00000579732.1
ENST00000578620.1
ENST00000542342.2
ENST00000255559.3
ENST00000579018.1
SLC39A11
solute carrier family 39, member 11
chr1_-_154928562 0.71 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr3_+_32280159 0.69 ENST00000458535.2
ENST00000307526.3
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr2_-_152590946 0.66 ENST00000172853.10
NEB
nebulin
chr2_+_173600514 0.64 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr14_-_90085458 0.64 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr14_-_92413727 0.64 ENST00000267620.10
FBLN5
fibulin 5
chr9_+_90112117 0.63 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr2_-_75788038 0.61 ENST00000393913.3
ENST00000410113.1
EVA1A
eva-1 homolog A (C. elegans)
chr12_+_48357401 0.60 ENST00000429772.2
ENST00000449758.2
TMEM106C
transmembrane protein 106C
chr6_-_42016385 0.57 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr12_+_48357340 0.56 ENST00000256686.6
ENST00000549288.1
ENST00000552561.1
ENST00000546749.1
ENST00000552546.1
ENST00000550552.1
TMEM106C
transmembrane protein 106C
chr1_-_55352834 0.56 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr17_+_73521763 0.54 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr19_+_55996565 0.52 ENST00000587400.1
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr12_+_56324933 0.51 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr6_+_18387570 0.50 ENST00000259939.3
RNF144B
ring finger protein 144B
chr11_-_118122996 0.50 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr8_+_98881268 0.50 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr3_-_49851313 0.46 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr6_-_31697255 0.46 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr5_+_122110691 0.45 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2
sorting nexin 2
chr1_+_110754094 0.45 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr4_-_54457783 0.45 ENST00000263925.7
ENST00000512247.1
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr19_-_56109119 0.44 ENST00000587678.1
FIZ1
FLT3-interacting zinc finger 1
chr3_+_182511266 0.44 ENST00000323116.5
ENST00000493826.1
ATP11B
ATPase, class VI, type 11B
chr16_+_30006997 0.44 ENST00000304516.7
INO80E
INO80 complex subunit E
chr21_-_39870339 0.43 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr6_-_41888814 0.43 ENST00000409060.1
ENST00000265350.4
MED20
mediator complex subunit 20
chr14_+_75746781 0.43 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr5_-_137071756 0.43 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr13_+_80055581 0.42 ENST00000487865.1
NDFIP2
Nedd4 family interacting protein 2
chr2_+_170590321 0.42 ENST00000392647.2
KLHL23
kelch-like family member 23
chr11_+_118175596 0.42 ENST00000528600.1
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr16_-_46865286 0.42 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr6_-_31697563 0.41 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr8_-_8318847 0.41 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr2_-_152590982 0.41 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
NEB
nebulin
chr7_+_77428066 0.41 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr11_+_118175132 0.40 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr7_-_27196267 0.40 ENST00000242159.3
HOXA7
homeobox A7
chr1_+_66999268 0.39 ENST00000371039.1
ENST00000424320.1
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr14_+_75746340 0.39 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr5_+_78532003 0.38 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr12_-_80084333 0.38 ENST00000552637.1
PAWR
PRKC, apoptosis, WT1, regulator
chr2_-_220436248 0.38 ENST00000265318.4
OBSL1
obscurin-like 1
chr13_+_80055284 0.38 ENST00000218652.7
NDFIP2
Nedd4 family interacting protein 2
chr1_-_28969517 0.35 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr11_+_111789580 0.35 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr4_-_6202247 0.35 ENST00000409021.3
ENST00000409371.3
JAKMIP1
janus kinase and microtubule interacting protein 1
chr8_-_103424986 0.34 ENST00000521922.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chrX_-_30326445 0.33 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chrX_-_134049233 0.33 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr12_-_52585765 0.33 ENST00000313234.5
ENST00000394815.2
KRT80
keratin 80
chr3_-_194991876 0.32 ENST00000310380.6
XXYLT1
xyloside xylosyltransferase 1
chr7_-_122526499 0.31 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr12_+_125549973 0.31 ENST00000536752.1
ENST00000261686.6
AACS
acetoacetyl-CoA synthetase
chr1_+_155051305 0.31 ENST00000368408.3
EFNA3
ephrin-A3
chr2_+_136289030 0.30 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1
R3H domain containing 1
chr1_-_156675368 0.29 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr15_-_34628951 0.28 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr11_+_128634589 0.28 ENST00000281428.8
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr17_+_9548845 0.28 ENST00000570475.1
ENST00000285199.7
USP43
ubiquitin specific peptidase 43
chr6_-_33281979 0.27 ENST00000426633.2
ENST00000467025.1
TAPBP
TAP binding protein (tapasin)
chr17_+_27895609 0.27 ENST00000581411.2
ENST00000301057.7
TP53I13
tumor protein p53 inducible protein 13
chr11_+_7618413 0.26 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_-_49722523 0.26 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr9_+_140172200 0.26 ENST00000357503.2
TOR4A
torsin family 4, member A
chr17_+_72744791 0.26 ENST00000583369.1
ENST00000262613.5
SLC9A3R1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
chr1_-_160990886 0.25 ENST00000537746.1
F11R
F11 receptor
chr7_+_130794846 0.25 ENST00000421797.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr19_+_14017116 0.25 ENST00000589606.1
CC2D1A
coiled-coil and C2 domain containing 1A
chr2_+_136343820 0.25 ENST00000410054.1
R3HDM1
R3H domain containing 1
chr16_+_103816 0.25 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr8_-_103424916 0.25 ENST00000220959.4
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr12_+_56324756 0.24 ENST00000331886.5
ENST00000555090.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr2_-_29297127 0.24 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr2_-_136288740 0.24 ENST00000264159.6
ENST00000536680.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr6_-_39290316 0.23 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
KCNK16
potassium channel, subfamily K, member 16
chr8_-_103668114 0.23 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr11_-_88070920 0.23 ENST00000524463.1
ENST00000227266.5
CTSC
cathepsin C
chr19_+_35940486 0.23 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr5_-_141257954 0.23 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr5_-_159739532 0.23 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr12_-_123752624 0.22 ENST00000542174.1
ENST00000535796.1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr1_+_45478568 0.22 ENST00000428106.1
UROD
uroporphyrinogen decarboxylase
chrX_-_6146876 0.22 ENST00000381095.3
NLGN4X
neuroligin 4, X-linked
chr4_+_106816644 0.22 ENST00000506666.1
ENST00000503451.1
NPNT
nephronectin
chr6_+_31783291 0.22 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
HSPA1A
heat shock 70kDa protein 1A
chr3_+_52454971 0.22 ENST00000465863.1
PHF7
PHD finger protein 7
chr15_-_45670924 0.21 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr3_-_178984759 0.21 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr14_-_20923195 0.21 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr11_-_119252359 0.21 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr8_-_103425047 0.21 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr12_+_56325812 0.21 ENST00000394147.1
ENST00000551156.1
ENST00000553783.1
ENST00000557080.1
ENST00000432422.3
ENST00000556001.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr19_-_18391708 0.21 ENST00000600972.1
JUND
jun D proto-oncogene
chr2_-_43823093 0.21 ENST00000405006.4
THADA
thyroid adenoma associated
chr19_-_53770972 0.20 ENST00000311170.4
VN1R4
vomeronasal 1 receptor 4
chr4_-_177190364 0.20 ENST00000296525.3
ASB5
ankyrin repeat and SOCS box containing 5
chr16_+_30006615 0.20 ENST00000563197.1
INO80E
INO80 complex subunit E
chr2_+_176987088 0.20 ENST00000249499.6
HOXD9
homeobox D9
chr17_-_56429500 0.20 ENST00000225504.3
SUPT4H1
suppressor of Ty 4 homolog 1 (S. cerevisiae)
chr1_-_156675535 0.20 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr7_-_8301682 0.19 ENST00000396675.3
ENST00000430867.1
ICA1
islet cell autoantigen 1, 69kDa
chr4_-_140223670 0.19 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr7_+_18535893 0.19 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chr17_-_39538550 0.19 ENST00000394001.1
KRT34
keratin 34
chr7_-_8301869 0.18 ENST00000402384.3
ICA1
islet cell autoantigen 1, 69kDa
chr7_-_8301768 0.18 ENST00000265577.7
ICA1
islet cell autoantigen 1, 69kDa
chr5_-_54281407 0.18 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr9_-_35619539 0.17 ENST00000396757.1
CD72
CD72 molecule
chr12_+_50497784 0.17 ENST00000548814.1
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr12_+_58176525 0.16 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr17_+_37793318 0.16 ENST00000336308.5
STARD3
StAR-related lipid transfer (START) domain containing 3
chr20_+_33589048 0.16 ENST00000446156.1
ENST00000453028.1
ENST00000435272.1
ENST00000433934.2
ENST00000456649.1
MYH7B
myosin, heavy chain 7B, cardiac muscle, beta
chr20_+_44044717 0.16 ENST00000279036.6
ENST00000279035.9
ENST00000372689.5
ENST00000545755.1
ENST00000341555.5
ENST00000535404.1
ENST00000543458.2
ENST00000432270.1
PIGT
phosphatidylinositol glycan anchor biosynthesis, class T
chr8_-_99837856 0.16 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr16_+_32077386 0.16 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chrX_-_16887963 0.16 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr6_-_39399087 0.16 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
KIF6
kinesin family member 6
chr4_+_169418255 0.16 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr3_-_69435224 0.16 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chr4_-_140223614 0.16 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_-_42573650 0.16 ENST00000593562.1
GRIK5
glutamate receptor, ionotropic, kainate 5
chr2_-_43823119 0.16 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA
thyroid adenoma associated
chr10_+_1102303 0.16 ENST00000381329.1
WDR37
WD repeat domain 37
chr19_-_7939319 0.16 ENST00000539422.1
CTD-3193O13.9
Protein FLJ22184
chr12_-_75603236 0.16 ENST00000540018.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr12_-_13248598 0.16 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr13_+_76362974 0.16 ENST00000497947.2
LMO7
LIM domain 7
chrX_-_153637612 0.15 ENST00000369807.1
ENST00000369808.3
DNASE1L1
deoxyribonuclease I-like 1
chr7_-_8302164 0.15 ENST00000447326.1
ENST00000406470.2
ICA1
islet cell autoantigen 1, 69kDa
chr9_-_134406565 0.15 ENST00000372210.3
ENST00000372211.3
UCK1
uridine-cytidine kinase 1
chr10_+_104614008 0.15 ENST00000369883.3
C10orf32
chromosome 10 open reading frame 32
chr19_+_39881951 0.15 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr19_-_46272106 0.15 ENST00000560168.1
SIX5
SIX homeobox 5
chr16_-_57513657 0.15 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr7_+_20370746 0.15 ENST00000222573.4
ITGB8
integrin, beta 8
chr12_-_75603482 0.15 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr12_-_118406028 0.15 ENST00000425217.1
KSR2
kinase suppressor of ras 2
chr19_+_35739782 0.15 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr4_+_5712898 0.14 ENST00000264956.6
ENST00000382674.2
EVC
Ellis van Creveld syndrome
chr11_+_33279850 0.14 ENST00000531504.1
ENST00000456517.1
HIPK3
homeodomain interacting protein kinase 3
chr8_-_99954788 0.14 ENST00000523601.1
STK3
serine/threonine kinase 3
chr17_+_37793378 0.14 ENST00000544210.2
ENST00000581894.1
ENST00000394250.4
ENST00000579479.1
ENST00000577248.1
ENST00000580611.1
STARD3
StAR-related lipid transfer (START) domain containing 3
chr2_+_28113583 0.14 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr8_-_145018905 0.14 ENST00000398774.2
PLEC
plectin
chr10_+_115614370 0.13 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr19_+_14017003 0.13 ENST00000318003.7
CC2D1A
coiled-coil and C2 domain containing 1A
chr11_-_122931881 0.13 ENST00000526110.1
ENST00000227378.3
HSPA8
heat shock 70kDa protein 8
chr7_+_128784712 0.13 ENST00000289407.4
TSPAN33
tetraspanin 33
chr4_-_164534657 0.13 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr3_-_52860850 0.13 ENST00000441637.2
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr7_-_37488834 0.13 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr1_+_100315613 0.13 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr19_-_18392422 0.12 ENST00000252818.3
JUND
jun D proto-oncogene
chrX_-_118827333 0.12 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
SEPT6
septin 6
chr19_+_11658655 0.12 ENST00000588935.1
CNN1
calponin 1, basic, smooth muscle
chr17_-_39183452 0.12 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr14_+_22739823 0.12 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr5_-_177423243 0.12 ENST00000308304.2
PROP1
PROP paired-like homeobox 1
chr1_+_150954493 0.12 ENST00000368947.4
ANXA9
annexin A9
chr7_-_97881429 0.12 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr17_+_45286387 0.11 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4
myosin, light chain 4, alkali; atrial, embryonic

Network of associatons between targets according to the STRING database.

First level regulatory network of FIGLA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3 1.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 1.1 GO:1903284 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 2.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.1 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.1 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 0.9 GO:0050917 sensory perception of umami taste(GO:0050917)
0.2 0.8 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 0.8 GO:0072244 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 1.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.8 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.6 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.4 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.4 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.8 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 1.7 GO:0070673 response to interleukin-18(GO:0070673)
0.1 0.4 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.4 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.3 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 1.0 GO:0006983 ER overload response(GO:0006983)
0.1 18.1 GO:0031424 keratinization(GO:0031424)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 2.0 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.2 GO:0072189 ureter development(GO:0072189)
0.1 0.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.8 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.3 GO:0097195 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.4 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.1 2.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.7 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.4 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.9 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.4 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 1.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.3 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:1903823 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.2 GO:0071964 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 1.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0003064 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.5 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:1900369 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.1 GO:0060488 dichotomous subdivision of terminal units involved in lung branching(GO:0060448) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3 2.8 GO:0071953 elastic fiber(GO:0071953)
0.3 0.8 GO:0005608 laminin-3 complex(GO:0005608)
0.2 16.2 GO:0045095 keratin filament(GO:0045095)
0.1 1.1 GO:0035976 AP1 complex(GO:0035976)
0.1 1.1 GO:0097443 sorting endosome(GO:0097443)
0.1 0.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.0 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.0 GO:0000502 proteasome complex(GO:0000502)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 1.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.9 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 1.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 1.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 2.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.8 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 2.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.9 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 1.5 GO:0030552 cAMP binding(GO:0030552)
0.0 1.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 1.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 3.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.0 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.0 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 3.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)