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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FOSB

Z-value: 0.65

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Transcription factors associated with FOSB

Gene Symbol Gene ID Gene Info
FOSB
ENSG00000125740.9 FosB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSBhg19_v2_chr19_+_45973120_459731710.271.9e-01Click!

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_30960915 2.89 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr13_+_32838801 1.97 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr11_+_59522837 1.52 ENST00000437946.2
STX3
syntaxin 3
chr3_-_149293990 1.42 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr1_-_95007193 1.28 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr2_+_87754989 1.10 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr2_+_87754887 1.10 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
LINC00152
long intergenic non-protein coding RNA 152
chr2_+_87755054 1.09 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr3_-_32022733 1.08 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chr20_+_34742650 0.96 ENST00000373945.1
ENST00000338074.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr3_-_18466026 0.91 ENST00000417717.2
SATB1
SATB homeobox 1
chr3_-_141747950 0.82 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_+_116312411 0.80 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr3_-_141747439 0.77 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr16_-_4665023 0.73 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr4_-_89080003 0.71 ENST00000237612.3
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr6_+_74405501 0.69 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr2_-_238499303 0.68 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr16_-_4664860 0.68 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr6_+_74405804 0.67 ENST00000287097.5
CD109
CD109 molecule
chr2_+_28615669 0.65 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr8_+_120220561 0.65 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr1_-_85870177 0.61 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr8_-_125384927 0.60 ENST00000297632.6
TMEM65
transmembrane protein 65
chr5_+_175288631 0.59 ENST00000509837.1
CPLX2
complexin 2
chr5_-_176923846 0.59 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr2_+_16080659 0.58 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr12_-_95510743 0.57 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr5_-_176923803 0.55 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr12_-_15114658 0.51 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_+_169926047 0.51 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr17_+_35851570 0.51 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr12_-_15114191 0.51 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr5_-_61031495 0.51 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
CTD-2170G1.2
chrX_+_41193407 0.50 ENST00000457138.2
ENST00000441189.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr11_-_119066545 0.50 ENST00000415318.1
CCDC153
coiled-coil domain containing 153
chr19_+_49377575 0.50 ENST00000600406.1
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr2_-_65593784 0.48 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr17_-_39769005 0.48 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr4_+_74606223 0.48 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr14_+_103801140 0.48 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
EIF5
eukaryotic translation initiation factor 5
chr4_+_170581213 0.47 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr11_+_128563948 0.47 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr3_-_141747459 0.47 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr14_+_73525265 0.46 ENST00000525161.1
RBM25
RNA binding motif protein 25
chr1_-_160231451 0.45 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr11_+_63448918 0.44 ENST00000341307.2
ENST00000356000.3
ENST00000542238.1
RTN3
reticulon 3
chr3_-_18466787 0.44 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr12_-_15114492 0.44 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr15_+_69373184 0.43 ENST00000558147.1
ENST00000440444.1
LINC00277
long intergenic non-protein coding RNA 277
chr6_+_155537771 0.42 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr4_+_108745711 0.40 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr18_+_21452964 0.40 ENST00000587184.1
LAMA3
laminin, alpha 3
chr19_+_47104553 0.38 ENST00000598871.1
ENST00000594523.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr18_+_21452804 0.37 ENST00000269217.6
LAMA3
laminin, alpha 3
chr16_+_2083265 0.36 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr12_-_95009837 0.36 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr2_+_89999259 0.35 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr14_-_23426270 0.35 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4
HAUS augmin-like complex, subunit 4
chr6_+_2988847 0.35 ENST00000380472.3
ENST00000605901.1
ENST00000454015.1
NQO2
LINC01011
NAD(P)H dehydrogenase, quinone 2
long intergenic non-protein coding RNA 1011
chr8_-_17752996 0.35 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr9_-_34662651 0.34 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr14_-_23426337 0.34 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4
HAUS augmin-like complex, subunit 4
chr7_+_142919130 0.34 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr14_-_23426322 0.33 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr16_+_31366455 0.33 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr3_-_196065248 0.32 ENST00000446879.1
ENST00000273695.3
TM4SF19
transmembrane 4 L six family member 19
chr1_+_26869597 0.32 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr2_+_90139056 0.32 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr19_-_18995029 0.32 ENST00000596048.1
CERS1
ceramide synthase 1
chr15_+_77287426 0.32 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr15_-_77363513 0.31 ENST00000267970.4
TSPAN3
tetraspanin 3
chr3_+_183894566 0.31 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr17_+_74734052 0.31 ENST00000590514.1
MFSD11
major facilitator superfamily domain containing 11
chr8_-_17752912 0.30 ENST00000398054.1
ENST00000381840.2
FGL1
fibrinogen-like 1
chr12_-_15114603 0.30 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr11_-_47207390 0.29 ENST00000539589.1
ENST00000528462.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr9_-_73029540 0.29 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr12_+_10366016 0.29 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr7_+_150065278 0.29 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr6_+_32121218 0.29 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr2_-_89340242 0.28 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr17_-_27503770 0.28 ENST00000533112.1
MYO18A
myosin XVIIIA
chr12_-_71182695 0.28 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr6_+_33043703 0.27 ENST00000418931.2
ENST00000535465.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr19_+_47104493 0.27 ENST00000291295.9
ENST00000597743.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr11_+_128563652 0.27 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr5_-_138534071 0.27 ENST00000394817.2
SIL1
SIL1 nucleotide exchange factor
chr3_-_53878644 0.27 ENST00000481668.1
ENST00000467802.1
CHDH
choline dehydrogenase
chr15_-_44486632 0.26 ENST00000484674.1
FRMD5
FERM domain containing 5
chr2_-_89521942 0.26 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr3_-_151034734 0.26 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr3_-_98241760 0.26 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1
claudin domain containing 1
chr11_-_2924720 0.26 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr5_+_140729649 0.26 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr1_-_179112189 0.25 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr5_+_53751445 0.24 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr1_+_27719148 0.24 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr11_-_102826434 0.24 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr17_+_80317121 0.24 ENST00000333437.4
TEX19
testis expressed 19
chr6_-_38670897 0.24 ENST00000373365.4
GLO1
glyoxalase I
chr5_-_137071756 0.23 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr18_+_61442629 0.23 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr20_-_17539456 0.22 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr7_+_134528635 0.22 ENST00000445569.2
CALD1
caldesmon 1
chr1_-_236046872 0.22 ENST00000536965.1
LYST
lysosomal trafficking regulator
chr5_-_138533973 0.22 ENST00000507002.1
ENST00000505830.1
ENST00000508639.1
ENST00000265195.5
SIL1
SIL1 nucleotide exchange factor
chr16_+_71560023 0.21 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr9_-_124991124 0.21 ENST00000394319.4
ENST00000340587.3
LHX6
LIM homeobox 6
chr16_+_89724434 0.21 ENST00000568929.1
SPATA33
spermatogenesis associated 33
chr1_-_153029980 0.21 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr17_+_75315534 0.21 ENST00000590294.1
ENST00000329047.8
SEPT9
septin 9
chr7_-_142120321 0.21 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr3_-_98241358 0.20 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr16_+_71560154 0.20 ENST00000539698.3
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr13_+_102142296 0.20 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr6_-_31745037 0.20 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr6_+_44194762 0.20 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr12_-_51402984 0.20 ENST00000545993.2
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr17_+_74733744 0.20 ENST00000586689.1
ENST00000587661.1
ENST00000593181.1
ENST00000336509.4
ENST00000355954.3
MFSD11
major facilitator superfamily domain containing 11
chr2_+_102618428 0.19 ENST00000457817.1
IL1R2
interleukin 1 receptor, type II
chr2_-_238499131 0.19 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr14_-_23588816 0.19 ENST00000206513.5
CEBPE
CCAAT/enhancer binding protein (C/EBP), epsilon
chr5_-_141061759 0.18 ENST00000508305.1
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr22_-_32058166 0.18 ENST00000435900.1
ENST00000336566.4
PISD
phosphatidylserine decarboxylase
chr12_+_52695617 0.18 ENST00000293525.5
KRT86
keratin 86
chr19_+_36630454 0.18 ENST00000246533.3
CAPNS1
calpain, small subunit 1
chr20_+_48429356 0.17 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr5_-_141061777 0.17 ENST00000239440.4
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr17_-_79481666 0.17 ENST00000575659.1
ACTG1
actin, gamma 1
chr2_+_74741569 0.17 ENST00000233638.7
TLX2
T-cell leukemia homeobox 2
chr17_+_72426891 0.17 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr12_-_102591604 0.17 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr10_+_134901388 0.17 ENST00000392607.3
GPR123
G protein-coupled receptor 123
chr20_+_48429233 0.17 ENST00000417961.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr15_-_77363441 0.16 ENST00000346495.2
ENST00000424443.3
ENST00000561277.1
TSPAN3
tetraspanin 3
chr17_-_39942940 0.16 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP
junction plakoglobin
chr14_+_103800513 0.16 ENST00000560338.1
ENST00000560763.1
ENST00000558316.1
ENST00000558265.1
EIF5
eukaryotic translation initiation factor 5
chr1_+_247579451 0.16 ENST00000391828.3
ENST00000366497.2
NLRP3
NLR family, pyrin domain containing 3
chr7_+_2687173 0.16 ENST00000403167.1
TTYH3
tweety family member 3
chr15_-_77363375 0.15 ENST00000559494.1
TSPAN3
tetraspanin 3
chr16_+_28875126 0.15 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr6_-_24877490 0.15 ENST00000540914.1
ENST00000378023.4
FAM65B
family with sequence similarity 65, member B
chr17_-_27045405 0.15 ENST00000430132.2
RAB34
RAB34, member RAS oncogene family
chr11_-_2924970 0.15 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr1_-_24126051 0.14 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr12_+_57849048 0.14 ENST00000266646.2
INHBE
inhibin, beta E
chr14_-_75536182 0.13 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr5_-_158636512 0.13 ENST00000424310.2
RNF145
ring finger protein 145
chr5_+_147582348 0.13 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr17_-_27045427 0.13 ENST00000301043.6
ENST00000412625.1
RAB34
RAB34, member RAS oncogene family
chr18_-_268019 0.13 ENST00000261600.6
THOC1
THO complex 1
chr17_-_27045165 0.13 ENST00000436730.3
ENST00000450529.1
ENST00000583538.1
ENST00000419712.3
ENST00000580843.2
ENST00000582934.1
ENST00000415040.2
ENST00000353676.5
ENST00000453384.3
ENST00000447716.1
RAB34
RAB34, member RAS oncogene family
chr2_-_218706877 0.13 ENST00000446688.1
TNS1
tensin 1
chr6_+_43027595 0.13 ENST00000259708.3
ENST00000472792.1
ENST00000479388.1
ENST00000460283.1
ENST00000394056.2
KLC4
kinesin light chain 4
chr6_+_106959718 0.13 ENST00000369066.3
AIM1
absent in melanoma 1
chr18_+_9885760 0.12 ENST00000536353.2
ENST00000584255.1
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr19_-_39264072 0.12 ENST00000599035.1
ENST00000378626.4
LGALS7
lectin, galactoside-binding, soluble, 7
chr11_-_2193025 0.12 ENST00000333684.5
ENST00000381178.1
ENST00000381175.1
ENST00000352909.3
TH
tyrosine hydroxylase
chr19_-_47128294 0.12 ENST00000596260.1
ENST00000597185.1
ENST00000598865.1
ENST00000594275.1
ENST00000291294.2
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr1_+_101003687 0.12 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr2_-_220083076 0.11 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr17_-_25568687 0.11 ENST00000581944.1
RP11-663N22.1
RP11-663N22.1
chr11_-_47198380 0.11 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr6_+_47624172 0.11 ENST00000507065.1
ENST00000296862.1
GPR111
G protein-coupled receptor 111
chr4_+_84457250 0.11 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr3_-_113464906 0.11 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr1_+_44584522 0.11 ENST00000372299.3
KLF17
Kruppel-like factor 17
chrX_+_99839799 0.11 ENST00000373031.4
TNMD
tenomodulin
chr1_-_21059029 0.11 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2D5
SH2 domain containing 5
chr7_+_99647389 0.11 ENST00000543588.1
ENST00000292450.4
ENST00000456748.2
ZSCAN21
zinc finger and SCAN domain containing 21
chr14_-_94854926 0.11 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr10_+_17270214 0.11 ENST00000544301.1
VIM
vimentin
chr5_+_143191726 0.11 ENST00000289448.2
HMHB1
histocompatibility (minor) HB-1
chr17_+_76311791 0.10 ENST00000586321.1
AC061992.2
AC061992.2
chr1_+_223900034 0.10 ENST00000295006.5
CAPN2
calpain 2, (m/II) large subunit
chr17_+_30771279 0.10 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr3_-_51994694 0.10 ENST00000395014.2
PCBP4
poly(rC) binding protein 4
chr5_+_43602750 0.10 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr2_-_136633940 0.10 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr2_+_216974020 0.10 ENST00000392132.2
ENST00000417391.1
XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr2_+_27237615 0.09 ENST00000458529.1
ENST00000402218.1
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr11_-_75201791 0.09 ENST00000529721.1
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr12_-_54813229 0.09 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr4_+_3388057 0.09 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr11_+_68671310 0.09 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr5_-_43412418 0.09 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr15_+_59903975 0.09 ENST00000560585.1
ENST00000396065.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr8_-_59572093 0.09 ENST00000427130.2
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr3_+_113465866 0.09 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr17_-_27044810 0.09 ENST00000395242.2
RAB34
RAB34, member RAS oncogene family
chr17_-_27044903 0.09 ENST00000395245.3
RAB34
RAB34, member RAS oncogene family
chr14_+_58765103 0.09 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr7_-_130598059 0.09 ENST00000432045.2
MIR29B1
microRNA 29a
chr18_-_40695604 0.08 ENST00000590910.1
ENST00000326695.5
ENST00000589109.1
ENST00000282028.4
RIT2
Ras-like without CAAX 2
chr6_-_149806105 0.08 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D
zinc finger CCCH-type containing 12D
chr4_+_41983713 0.08 ENST00000333141.5
DCAF4L1
DDB1 and CUL4 associated factor 4-like 1
chr17_+_75446819 0.08 ENST00000541152.2
ENST00000591704.1
SEPT9
septin 9
chr2_+_27505260 0.08 ENST00000380075.2
ENST00000296098.4
TRIM54
tripartite motif containing 54
chr4_+_76481258 0.08 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0035378 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.4 1.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.3 1.8 GO:0071461 cellular response to redox state(GO:0071461)
0.2 2.0 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 1.4 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 1.5 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 0.9 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.5 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 0.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.3 GO:0036146 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.1 1.4 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.3 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.5 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 1.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 2.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.6 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.3 GO:0051414 response to cortisol(GO:0051414)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0052314 terpene metabolic process(GO:0042214) phytoalexin metabolic process(GO:0052314)
0.0 0.6 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 1.1 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.4 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0032621 interleukin-18 production(GO:0032621) positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.0 GO:0061743 motor learning(GO:0061743)
0.0 0.0 GO:0060164 amygdala development(GO:0021764) regulation of timing of neuron differentiation(GO:0060164)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.0 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798) mammary gland specification(GO:0060594)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.9 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.4 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.2 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 1.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.4 1.5 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.8 GO:0005610 laminin-5 complex(GO:0005610)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.8 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 2.4 GO:0000922 spindle pole(GO:0000922)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.5 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.2 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 1.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 2.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras