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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FOSL1

Z-value: 1.00

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Transcription factors associated with FOSL1

Gene Symbol Gene ID Gene Info
FOSL1
ENSG00000175592.4 FOS like 1, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL1hg19_v2_chr11_-_65667997_656680440.801.4e-06Click!

Activity profile of FOSL1 motif

Sorted Z-values of FOSL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_183155373 7.05 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr15_+_89182178 7.05 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 6.92 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr11_-_102668879 6.59 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr2_+_152214098 6.35 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr21_+_26934165 6.23 ENST00000456917.1
MIR155HG
MIR155 host gene (non-protein coding)
chr4_+_74606223 6.22 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr15_+_89181974 6.12 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr1_-_153521597 5.69 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr1_-_153521714 5.07 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr1_-_8000872 4.75 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr1_-_95007193 4.74 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr7_+_55177416 4.70 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr10_-_6019984 4.59 ENST00000525219.2
IL15RA
interleukin 15 receptor, alpha
chr10_-_6019552 4.49 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
IL15RA
interleukin 15 receptor, alpha
chr5_+_35856951 4.40 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr18_+_61554932 4.03 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr4_-_122085469 3.52 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr10_+_104155450 3.46 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr1_+_156084461 3.32 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr17_+_21191341 3.26 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr6_+_138188551 3.02 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_-_44233361 2.93 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr10_-_6019455 2.92 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
IL15RA
interleukin 15 receptor, alpha
chr17_+_74381343 2.88 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr11_+_35198243 2.75 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr1_+_169077172 2.65 ENST00000499679.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_155107820 2.58 ENST00000484157.1
SLC50A1
solute carrier family 50 (sugar efflux transporter), member 1
chr21_-_36421535 2.53 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr21_-_36421626 2.44 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr6_-_138428613 2.32 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chrX_-_154563889 2.28 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr16_+_57662138 2.23 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chr16_+_57662419 2.18 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr11_-_65667997 2.12 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr8_+_86157699 2.12 ENST00000321764.3
CA13
carbonic anhydrase XIII
chr1_-_209824643 2.07 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr11_-_65667884 2.05 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr11_-_2950642 2.00 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr18_+_55888767 1.99 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_-_150208320 1.97 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_-_56236734 1.95 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chr17_+_79650962 1.95 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr8_+_126442563 1.84 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr11_+_35198118 1.82 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44
CD44 molecule (Indian blood group)
chr11_-_65430554 1.75 ENST00000308639.9
ENST00000406246.3
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr1_-_6662919 1.73 ENST00000377658.4
ENST00000377663.3
KLHL21
kelch-like family member 21
chr4_-_114900831 1.70 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr6_+_83072923 1.62 ENST00000535040.1
TPBG
trophoblast glycoprotein
chr11_-_65430251 1.57 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr2_+_103035102 1.56 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr1_+_156096336 1.47 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr12_-_56236690 1.46 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr10_+_24755416 1.45 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr7_+_28725585 1.40 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr17_-_45928521 1.40 ENST00000536300.1
SP6
Sp6 transcription factor
chr17_+_4853442 1.37 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr6_+_151042224 1.36 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr17_-_28257080 1.31 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr18_+_61637159 1.30 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
SERPINB8
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr3_+_30648066 1.30 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr1_-_113247543 1.22 ENST00000414971.1
ENST00000534717.1
RHOC
ras homolog family member C
chr11_+_35639735 1.21 ENST00000317811.4
FJX1
four jointed box 1 (Drosophila)
chr7_+_128095900 1.21 ENST00000435296.2
HILPDA
hypoxia inducible lipid droplet-associated
chr5_-_59783882 1.19 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_+_38794797 1.16 ENST00000301246.5
ENST00000588605.1
C19orf33
chromosome 19 open reading frame 33
chr5_+_179247759 1.13 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1
sequestosome 1
chr6_-_84140757 1.12 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chrX_-_110513703 1.10 ENST00000324068.1
CAPN6
calpain 6
chr6_+_106546808 1.08 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr5_-_61031495 1.06 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
CTD-2170G1.2
chr17_+_74261277 1.05 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chr3_+_30647994 1.05 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr1_-_150208291 1.03 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr9_+_35673853 1.02 ENST00000378357.4
CA9
carbonic anhydrase IX
chr10_-_31288398 1.02 ENST00000538351.2
ZNF438
zinc finger protein 438
chr12_-_323689 1.01 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr6_-_46293378 1.01 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr16_+_30751953 0.98 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr1_+_156095951 0.97 ENST00000448611.2
ENST00000368297.1
LMNA
lamin A/C
chr12_+_7023735 0.97 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2
enolase 2 (gamma, neuronal)
chr1_-_150208363 0.95 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr11_+_12308447 0.94 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr11_-_3862206 0.93 ENST00000351018.4
RHOG
ras homolog family member G
chr11_-_9025541 0.92 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr1_+_150122034 0.92 ENST00000025469.6
ENST00000369124.4
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr2_+_69201705 0.91 ENST00000377938.2
GKN1
gastrokine 1
chrX_-_129244655 0.91 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chrX_-_129244454 0.90 ENST00000308167.5
ELF4
E74-like factor 4 (ets domain transcription factor)
chr17_+_7255208 0.89 ENST00000333751.3
KCTD11
potassium channel tetramerization domain containing 11
chr7_+_128095945 0.88 ENST00000257696.4
HILPDA
hypoxia inducible lipid droplet-associated
chr3_-_37216055 0.87 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr14_-_53258314 0.87 ENST00000216410.3
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr22_+_20861858 0.86 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
MED15
mediator complex subunit 15
chr8_-_70745575 0.86 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr6_+_45296048 0.85 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2
runt-related transcription factor 2
chr6_+_138483058 0.85 ENST00000251691.4
KIAA1244
KIAA1244
chr3_-_191000172 0.85 ENST00000427544.2
UTS2B
urotensin 2B
chr15_-_70388943 0.84 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr5_+_147582387 0.84 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr1_-_28520447 0.83 ENST00000539896.1
PTAFR
platelet-activating factor receptor
chr6_-_35888905 0.82 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr6_-_35888824 0.82 ENST00000361690.3
ENST00000512445.1
SRPK1
SRSF protein kinase 1
chr1_-_159894319 0.81 ENST00000320307.4
TAGLN2
transgelin 2
chr2_-_220173685 0.80 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr12_+_7023491 0.80 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr11_-_66103867 0.80 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr7_+_148395959 0.77 ENST00000325222.4
CUL1
cullin 1
chrX_-_48937503 0.76 ENST00000322995.8
WDR45
WD repeat domain 45
chr15_-_70388599 0.76 ENST00000560996.1
ENST00000558201.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr12_-_71182695 0.75 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr6_+_108487245 0.74 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr17_-_47287928 0.74 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr1_+_36621697 0.73 ENST00000373150.4
ENST00000373151.2
MAP7D1
MAP7 domain containing 1
chr6_+_25652432 0.73 ENST00000377961.2
SCGN
secretagogin, EF-hand calcium binding protein
chr10_+_123872483 0.72 ENST00000369001.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr1_-_67142710 0.71 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr1_-_150208412 0.71 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_-_53625958 0.71 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr8_-_27115931 0.71 ENST00000523048.1
STMN4
stathmin-like 4
chr19_+_35645618 0.71 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5
chr1_-_27816641 0.70 ENST00000430629.2
WASF2
WAS protein family, member 2
chr17_+_74261413 0.69 ENST00000587913.1
UBALD2
UBA-like domain containing 2
chr10_-_81708854 0.69 ENST00000372292.3
SFTPD
surfactant protein D
chr1_-_207224307 0.69 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr18_+_32556892 0.68 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr5_+_149877334 0.68 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr19_+_35645817 0.67 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr17_-_38911580 0.67 ENST00000312150.4
KRT25
keratin 25
chr1_-_28520384 0.66 ENST00000305392.3
PTAFR
platelet-activating factor receptor
chr1_+_36621529 0.65 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr1_-_111148241 0.64 ENST00000440270.1
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr16_+_83986827 0.64 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr3_-_196065248 0.64 ENST00000446879.1
ENST00000273695.3
TM4SF19
transmembrane 4 L six family member 19
chr19_-_46285646 0.64 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr22_-_30642782 0.64 ENST00000249075.3
LIF
leukemia inhibitory factor
chr3_+_48507621 0.63 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr19_+_35521616 0.62 ENST00000595652.1
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr20_-_62129163 0.62 ENST00000298049.7
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr1_-_150208498 0.62 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr11_-_76381029 0.62 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr19_-_10450287 0.61 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr2_-_85641162 0.59 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG
capping protein (actin filament), gelsolin-like
chr11_+_128563652 0.59 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr5_+_140868717 0.59 ENST00000252087.1
PCDHGC5
protocadherin gamma subfamily C, 5
chr18_-_49557 0.58 ENST00000308911.6
RP11-683L23.1
Tubulin beta-8 chain-like protein LOC260334
chr19_+_50431959 0.58 ENST00000595125.1
ATF5
activating transcription factor 5
chr17_-_56595196 0.57 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
MTMR4
myotubularin related protein 4
chr7_-_150721570 0.57 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B
autophagy related 9B
chrX_-_153285395 0.56 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chr10_-_4285923 0.56 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr22_+_39916558 0.56 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr19_-_10450328 0.55 ENST00000160262.5
ICAM3
intercellular adhesion molecule 3
chr3_+_48507210 0.55 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr3_-_11610255 0.53 ENST00000424529.2
VGLL4
vestigial like 4 (Drosophila)
chr15_+_98503922 0.53 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr1_-_109968973 0.53 ENST00000271308.4
ENST00000538610.1
PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr1_-_155947951 0.52 ENST00000313695.7
ENST00000497907.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr17_-_7590745 0.52 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53
tumor protein p53
chr16_+_88519669 0.51 ENST00000319555.3
ZFPM1
zinc finger protein, FOG family member 1
chr4_+_169753156 0.51 ENST00000393726.3
ENST00000507735.1
PALLD
palladin, cytoskeletal associated protein
chr16_-_1429627 0.51 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr12_+_69202975 0.50 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr1_+_155006300 0.50 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chr15_+_89631381 0.49 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr5_+_140729649 0.49 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chrX_-_153285251 0.49 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr17_-_18908040 0.49 ENST00000388995.6
FAM83G
family with sequence similarity 83, member G
chr6_+_64281906 0.48 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr3_-_48632593 0.47 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr4_-_123542224 0.47 ENST00000264497.3
IL21
interleukin 21
chr20_+_48429356 0.47 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr19_-_46285736 0.47 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr5_-_134914673 0.46 ENST00000512158.1
CXCL14
chemokine (C-X-C motif) ligand 14
chr1_+_152881014 0.46 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr17_-_39296739 0.46 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr17_-_9694614 0.46 ENST00000330255.5
ENST00000571134.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr11_-_111783919 0.46 ENST00000531198.1
ENST00000533879.1
CRYAB
crystallin, alpha B
chr7_+_134528635 0.45 ENST00000445569.2
CALD1
caldesmon 1
chr15_+_22892663 0.45 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
CYFIP1
cytoplasmic FMR1 interacting protein 1
chr21_-_43430440 0.45 ENST00000398505.3
ENST00000310826.5
ENST00000449949.1
ENST00000398499.1
ENST00000398497.2
ENST00000398511.3
ZBTB21
zinc finger and BTB domain containing 21
chr7_+_99006232 0.45 ENST00000403633.2
BUD31
BUD31 homolog (S. cerevisiae)
chr15_-_83316254 0.45 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr9_-_35111570 0.45 ENST00000378561.1
ENST00000603301.1
FAM214B
family with sequence similarity 214, member B
chr4_-_39034542 0.45 ENST00000344606.6
TMEM156
transmembrane protein 156
chr6_+_135818979 0.45 ENST00000421378.2
ENST00000579057.1
ENST00000436554.1
ENST00000438618.2
LINC00271
long intergenic non-protein coding RNA 271
chr11_+_5009424 0.44 ENST00000300762.1
MMP26
matrix metallopeptidase 26
chr9_+_140135665 0.44 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr12_+_69202795 0.44 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr7_+_150065278 0.44 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chrX_-_48901012 0.43 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr9_+_4985228 0.41 ENST00000381652.3
JAK2
Janus kinase 2
chr17_+_28256874 0.41 ENST00000541045.1
ENST00000536908.2
EFCAB5
EF-hand calcium binding domain 5
chr10_-_106240032 0.41 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr16_+_89988259 0.41 ENST00000554444.1
ENST00000556565.1
TUBB3
Tubulin beta-3 chain
chr8_-_27115903 0.41 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
STMN4
stathmin-like 4
chr22_+_17956618 0.41 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr16_-_31161380 0.41 ENST00000569305.1
ENST00000418068.2
ENST00000268281.4
PRSS36
protease, serine, 36
chr1_+_22333943 0.40 ENST00000400271.2
CELA3A
chymotrypsin-like elastase family, member 3A
chr11_+_706113 0.40 ENST00000318562.8
ENST00000533256.1
ENST00000534755.1
EPS8L2
EPS8-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 20.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.6 4.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.2 4.7 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.2 5.8 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
1.0 3.0 GO:0071947 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
1.0 2.9 GO:0046521 sphingoid catabolic process(GO:0046521)
0.9 3.5 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.9 2.6 GO:1901656 glycoside transport(GO:1901656)
0.8 3.3 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.8 4.7 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.8 2.3 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.7 4.2 GO:0007296 vitellogenesis(GO:0007296)
0.7 2.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.6 1.8 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6 4.6 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.5 4.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.5 2.6 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.5 2.1 GO:0035425 autocrine signaling(GO:0035425)
0.5 1.5 GO:1904303 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.5 1.4 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.4 5.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.4 3.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.4 2.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4 3.4 GO:0001554 luteolysis(GO:0001554)
0.3 9.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 0.9 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.3 2.9 GO:0042940 D-amino acid transport(GO:0042940)
0.3 1.3 GO:0051136 regulation of NK T cell differentiation(GO:0051136)
0.3 0.5 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.2 0.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 0.7 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.2 6.4 GO:0030728 ovulation(GO:0030728)
0.2 1.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 0.8 GO:1990502 dense core granule maturation(GO:1990502)
0.2 2.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2 0.3 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.2 0.3 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.2 0.7 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 0.5 GO:0010949 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.2 0.5 GO:0003192 mitral valve formation(GO:0003192)
0.2 2.1 GO:0002934 desmosome organization(GO:0002934)
0.2 1.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 0.5 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 0.3 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.2 0.5 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.9 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 2.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.6 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.8 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 1.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 4.5 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.6 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 1.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.3 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.1 5.3 GO:0043486 histone exchange(GO:0043486)
0.1 3.9 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.5 GO:0014858 positive regulation of skeletal muscle cell proliferation(GO:0014858) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 1.9 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.1 0.9 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.2 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.5 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.8 GO:0010265 SCF complex assembly(GO:0010265)
0.1 3.6 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 1.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.7 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 1.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 3.9 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 1.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 1.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.4 GO:2000809 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.7 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 1.0 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.2 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.9 GO:0051451 myoblast migration(GO:0051451)
0.1 1.5 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.1 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 0.5 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 1.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 3.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.6 GO:0014870 response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.8 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 1.9 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 1.4 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.5 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.6 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 1.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.4 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.8 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.8 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 1.0 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 1.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 1.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0018202 UTP biosynthetic process(GO:0006228) peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0002385 mucosal immune response(GO:0002385)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0005607 laminin-2 complex(GO:0005607)
1.6 4.7 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
1.1 3.3 GO:0071159 NF-kappaB complex(GO:0071159)
0.9 3.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.7 4.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.6 1.9 GO:0033565 ESCRT-0 complex(GO:0033565)
0.6 5.8 GO:0005638 lamin filament(GO:0005638)
0.4 3.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 1.1 GO:0044753 amphisome(GO:0044753)
0.3 0.9 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 2.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 2.0 GO:0005610 laminin-5 complex(GO:0005610)
0.3 5.3 GO:0000812 Swr1 complex(GO:0000812)
0.2 19.6 GO:0015030 Cajal body(GO:0015030)
0.2 1.7 GO:0005827 polar microtubule(GO:0005827)
0.2 1.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.5 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 2.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.6 GO:1990037 Lewy body core(GO:1990037)
0.1 2.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 5.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.1 GO:0030057 desmosome(GO:0030057)
0.1 1.0 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0033010 paranodal junction(GO:0033010)
0.0 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 1.0 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 2.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.0 GO:0005771 multivesicular body(GO:0005771)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 2.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 2.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.5 GO:0031904 endosome lumen(GO:0031904)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 6.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 6.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 13.8 GO:0005730 nucleolus(GO:0005730)
0.0 10.2 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 20.1 GO:0008859 exoribonuclease II activity(GO:0008859)
1.5 4.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.9 4.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.6 2.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.5 2.9 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.4 3.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 3.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 10.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 0.9 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 3.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 2.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 1.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 1.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 3.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 0.5 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.2 0.7 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 1.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 1.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 0.5 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 0.4 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 2.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 4.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 17.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 3.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 1.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 1.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 6.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 1.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 2.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.1 0.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.1 3.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 7.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 1.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.5 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 2.6 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.7 GO:0044548 S100 protein binding(GO:0044548)
0.0 4.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 5.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 5.6 GO:0001047 core promoter binding(GO:0001047)
0.0 0.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 10.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 3.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 10.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 8.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 4.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.7 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 7.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 9.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 6.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 4.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.7 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.3 6.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 4.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 4.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 20.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 3.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 6.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.2 4.6 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 2.7 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 3.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 4.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 0.5 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 2.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 10.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 5.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.0 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 5.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels