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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FOSL2_SMARCC1

Z-value: 0.79

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Transcription factors associated with FOSL2_SMARCC1

Gene Symbol Gene ID Gene Info
ENSG00000075426.7 FOS like 2, AP-1 transcription factor subunit
ENSG00000173473.6 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL2hg19_v2_chr2_+_28615669_286157330.349.3e-02Click!
SMARCC1hg19_v2_chr3_-_47823298_478234230.271.9e-01Click!

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_74606223 3.58 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr7_+_30960915 2.87 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr12_-_49259643 2.37 ENST00000309739.5
Rho family GTPase 1
chr13_+_32838801 2.13 ENST00000542859.1
furry homolog (Drosophila)
chr15_+_67420441 2.05 ENST00000558894.1
SMAD family member 3
chr15_+_67458357 1.83 ENST00000537194.2
SMAD family member 3
chr10_+_104155450 1.81 ENST00000471698.1
ENST00000189444.6
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr21_+_26934165 1.73 ENST00000456917.1
MIR155 host gene (non-protein coding)
chr3_+_11178779 1.71 ENST00000438284.2
histamine receptor H1
chr15_+_67418047 1.43 ENST00000540846.2
SMAD family member 3
chr7_+_129932974 1.43 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
carboxypeptidase A4
chr2_+_169926047 1.32 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr5_-_176923846 1.24 ENST00000506537.1
PDZ and LIM domain 7 (enigma)
chr18_+_21452804 1.16 ENST00000269217.6
laminin, alpha 3
chr5_-_176923803 1.13 ENST00000506161.1
PDZ and LIM domain 7 (enigma)
chr7_+_150065278 1.10 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr4_+_156587979 1.09 ENST00000511507.1
guanylate cyclase 1, soluble, alpha 3
chr22_+_23046750 1.05 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr4_+_108745711 1.04 ENST00000394684.4
sphingomyelin synthase 2
chr16_-_4665023 0.96 ENST00000591897.1
UBA-like domain containing 1
chr2_+_201980827 0.94 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
CASP8 and FADD-like apoptosis regulator
chr2_+_102721023 0.88 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr16_-_4664860 0.88 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBA-like domain containing 1
chr7_+_73245193 0.85 ENST00000340958.2
claudin 4
chr2_+_152214098 0.84 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr17_+_21191341 0.83 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
mitogen-activated protein kinase kinase 3
chr11_+_35639735 0.82 ENST00000317811.4
four jointed box 1 (Drosophila)
chr3_+_184037466 0.82 ENST00000441154.1
eukaryotic translation initiation factor 4 gamma, 1
chr2_+_201981527 0.81 ENST00000441224.1
CASP8 and FADD-like apoptosis regulator
chr2_+_169923577 0.77 ENST00000432060.2
dehydrogenase/reductase (SDR family) member 9
chr7_+_48128194 0.76 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
uridine phosphorylase 1
chr5_+_150020214 0.76 ENST00000307662.4
synaptopodin
chr7_+_48128316 0.76 ENST00000341253.4
uridine phosphorylase 1
chr1_-_6662919 0.75 ENST00000377658.4
ENST00000377663.3
kelch-like family member 21
chr17_+_7255208 0.73 ENST00000333751.3
potassium channel tetramerization domain containing 11
chr21_-_35899113 0.73 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr6_-_44233361 0.69 ENST00000275015.5
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr3_+_124223586 0.69 ENST00000393496.1
kalirin, RhoGEF kinase
chr3_-_149293990 0.69 ENST00000472417.1
WW domain containing transcription regulator 1
chr7_+_94023873 0.69 ENST00000297268.6
collagen, type I, alpha 2
chr6_-_159239257 0.67 ENST00000337147.7
ENST00000392177.4
ezrin
chr2_+_36923830 0.65 ENST00000379242.3
ENST00000389975.3
vitrin
chr15_+_89182178 0.64 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr1_-_89488510 0.64 ENST00000564665.1
ENST00000370481.4
guanylate binding protein 3
chr6_+_138188551 0.63 ENST00000237289.4
ENST00000433680.1
tumor necrosis factor, alpha-induced protein 3
chr21_+_17961006 0.62 ENST00000602323.1
long intergenic non-protein coding RNA 478
chr16_+_58533951 0.62 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG family member 4
chr2_+_169923504 0.61 ENST00000357546.2
dehydrogenase/reductase (SDR family) member 9
chr11_+_101983176 0.61 ENST00000524575.1
Yes-associated protein 1
chr6_-_24877490 0.60 ENST00000540914.1
ENST00000378023.4
family with sequence similarity 65, member B
chr10_+_75670862 0.60 ENST00000446342.1
ENST00000372764.3
ENST00000372762.4
plasminogen activator, urokinase
chr12_-_56236734 0.59 ENST00000548629.1
matrix metallopeptidase 19
chr15_+_59903975 0.59 ENST00000560585.1
ENST00000396065.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr15_+_89181974 0.58 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr9_-_74979420 0.58 ENST00000343431.2
ENST00000376956.3
zinc finger, AN1-type domain 5
chr8_-_141774467 0.58 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr1_-_160231451 0.55 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr6_+_106546808 0.55 ENST00000369089.3
PR domain containing 1, with ZNF domain
chr2_-_145275228 0.55 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
zinc finger E-box binding homeobox 2
chr12_+_100660909 0.55 ENST00000549687.1
SCY1-like 2 (S. cerevisiae)
chr15_+_89182156 0.54 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr14_+_22748980 0.53 ENST00000390465.2
T cell receptor alpha variable 38-2/delta variable 8
chrX_+_41193407 0.52 ENST00000457138.2
ENST00000441189.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr1_-_156675368 0.51 ENST00000368222.3
cellular retinoic acid binding protein 2
chr19_+_13842559 0.48 ENST00000586600.1
coiled-coil domain containing 130
chr19_-_14628645 0.48 ENST00000598235.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr9_-_73029540 0.47 ENST00000377126.2
Kruppel-like factor 9
chr5_+_179247759 0.47 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
sequestosome 1
chr11_-_8832182 0.47 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
suppression of tumorigenicity 5
chr20_+_48429356 0.47 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr18_+_61637159 0.46 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr14_+_55221541 0.46 ENST00000555192.1
sterile alpha motif domain containing 4A
chr7_-_98467543 0.46 ENST00000345589.4
transmembrane protein 130
chr16_+_83986827 0.45 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chr11_-_76381029 0.45 ENST00000407242.2
ENST00000421973.1
leucine rich repeat containing 32
chr7_-_98467629 0.44 ENST00000339375.4
transmembrane protein 130
chr2_-_219134822 0.43 ENST00000444053.1
ENST00000248450.4
angio-associated, migratory cell protein
chr14_-_25103388 0.42 ENST00000526004.1
ENST00000415355.3
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr3_+_191046810 0.42 ENST00000392455.3
ENST00000392456.3
coiled-coil domain containing 50
chr16_+_57662138 0.41 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
G protein-coupled receptor 56
chr3_-_32022733 0.41 ENST00000438237.2
ENST00000396556.2
oxysterol binding protein-like 10
chr14_-_25103472 0.41 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr3_+_69134080 0.41 ENST00000273258.3
ADP-ribosylation-like factor 6 interacting protein 5
chr16_+_31404624 0.41 ENST00000389202.2
integrin, alpha D
chr7_+_134528635 0.41 ENST00000445569.2
caldesmon 1
chr19_+_49377575 0.41 ENST00000600406.1
protein phosphatase 1, regulatory subunit 15A
chr3_+_19988885 0.41 ENST00000422242.1
RAB5A, member RAS oncogene family
chr11_+_128563948 0.40 ENST00000534087.2
Fli-1 proto-oncogene, ETS transcription factor
chr17_+_61571746 0.40 ENST00000579409.1
angiotensin I converting enzyme
chr5_+_177540444 0.40 ENST00000274605.5
NEDD4 binding protein 3
chr12_+_9144626 0.39 ENST00000543895.1
killer cell lectin-like receptor subfamily G, member 1
chr17_-_7493390 0.39 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SRY (sex determining region Y)-box 15
chr3_+_184038073 0.39 ENST00000428387.1
ENST00000434061.2
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_244006528 0.39 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr3_-_187454281 0.38 ENST00000232014.4
B-cell CLL/lymphoma 6
chr4_-_102268628 0.38 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
protein phosphatase 3, catalytic subunit, alpha isozyme
chr19_+_36630855 0.38 ENST00000589146.1
calpain, small subunit 1
chr10_+_86088337 0.38 ENST00000359979.4
coiled-coil serine-rich protein 2
chr1_+_36554470 0.37 ENST00000373178.4
ADP-ribosylhydrolase like 2
chr20_+_48429233 0.37 ENST00000417961.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr11_+_128563652 0.37 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr7_-_98467489 0.37 ENST00000416379.2
transmembrane protein 130
chr11_-_118134997 0.37 ENST00000278937.2
myelin protein zero-like 2
chr5_-_138534071 0.36 ENST00000394817.2
SIL1 nucleotide exchange factor
chr2_-_220173685 0.36 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
protein tyrosine phosphatase, receptor type, N
chr16_+_57662419 0.36 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
G protein-coupled receptor 56
chr4_-_102268484 0.36 ENST00000394853.4
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_+_30648066 0.36 ENST00000359013.4
transforming growth factor, beta receptor II (70/80kDa)
chr6_+_74405501 0.35 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr1_-_202777535 0.35 ENST00000367264.2
lysine (K)-specific demethylase 5B
chr3_+_45067659 0.35 ENST00000296130.4
C-type lectin domain family 3, member B
chr11_-_65430251 0.35 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr6_+_36410762 0.34 ENST00000483557.1
ENST00000498267.1
ENST00000544295.1
ENST00000449081.2
ENST00000536244.1
ENST00000460983.1
potassium channel tetramerization domain containing 20
chr6_+_2988847 0.34 ENST00000380472.3
ENST00000605901.1
ENST00000454015.1
NAD(P)H dehydrogenase, quinone 2
long intergenic non-protein coding RNA 1011
chr2_+_87755054 0.34 ENST00000423846.1
long intergenic non-protein coding RNA 152
chr20_+_33759854 0.34 ENST00000216968.4
protein C receptor, endothelial
chr20_-_634000 0.34 ENST00000381962.3
sulfiredoxin 1
chr5_+_138089100 0.34 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr1_+_201159914 0.33 ENST00000335211.4
ENST00000451870.2
ENST00000295591.8
immunoglobulin-like and fibronectin type III domain containing 1
chr14_+_103801140 0.33 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
eukaryotic translation initiation factor 5
chr6_+_74405804 0.33 ENST00000287097.5
CD109 molecule
chr22_+_22550113 0.32 ENST00000390285.3
immunoglobulin lambda variable 6-57
chr3_+_49027308 0.32 ENST00000383729.4
ENST00000343546.4
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr11_-_6341844 0.32 ENST00000303927.3
protein kinase C, delta binding protein
chr1_+_222988406 0.32 ENST00000448808.1
ENST00000457636.1
ENST00000439440.1
RP11-452F19.3
chr18_+_52495426 0.32 ENST00000262094.5
RAB27B, member RAS oncogene family
chr5_+_140729649 0.32 ENST00000523390.1
protocadherin gamma subfamily B, 1
chr9_+_92219919 0.31 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chr3_+_30647994 0.31 ENST00000295754.5
transforming growth factor, beta receptor II (70/80kDa)
chr19_-_6670128 0.31 ENST00000245912.3
tumor necrosis factor (ligand) superfamily, member 14
chr19_-_4559814 0.31 ENST00000586582.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr17_+_30771279 0.31 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr2_+_87754887 0.31 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
long intergenic non-protein coding RNA 152
chr5_-_138533973 0.31 ENST00000507002.1
ENST00000505830.1
ENST00000508639.1
ENST00000265195.5
SIL1 nucleotide exchange factor
chr11_-_133715394 0.31 ENST00000299140.3
ENST00000532889.1
spermatogenesis associated 19
chr8_-_38325219 0.31 ENST00000533668.1
ENST00000413133.2
ENST00000397108.4
ENST00000526742.1
ENST00000525001.1
ENST00000425967.3
ENST00000529552.1
ENST00000397113.2
fibroblast growth factor receptor 1
chr5_+_140762268 0.31 ENST00000518325.1
protocadherin gamma subfamily A, 7
chr2_+_201980961 0.31 ENST00000342795.5
CASP8 and FADD-like apoptosis regulator
chr2_+_219135115 0.30 ENST00000248451.3
ENST00000273077.4
paroxysmal nonkinesigenic dyskinesia
chr19_-_51523412 0.30 ENST00000391805.1
ENST00000599077.1
kallikrein-related peptidase 10
chrX_+_135251835 0.30 ENST00000456445.1
four and a half LIM domains 1
chr1_+_89990431 0.30 ENST00000330947.2
ENST00000358200.4
leucine rich repeat containing 8 family, member B
chr12_+_9142131 0.30 ENST00000356986.3
ENST00000266551.4
killer cell lectin-like receptor subfamily G, member 1
chr7_+_128095945 0.30 ENST00000257696.4
hypoxia inducible lipid droplet-associated
chr8_+_126442563 0.30 ENST00000311922.3
tribbles pseudokinase 1
chr1_+_222988363 0.30 ENST00000450784.1
ENST00000426045.1
ENST00000457955.1
ENST00000444858.1
ENST00000435378.1
ENST00000441676.1
RP11-452F19.3
chr2_+_87754989 0.30 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
long intergenic non-protein coding RNA 152
chr7_+_128095900 0.30 ENST00000435296.2
hypoxia inducible lipid droplet-associated
chr7_+_112063192 0.30 ENST00000005558.4
interferon-related developmental regulator 1
chr1_-_160232312 0.29 ENST00000440682.1
DDB1 and CUL4 associated factor 8
chr3_+_127770455 0.29 ENST00000464451.1
Sec61 alpha 1 subunit (S. cerevisiae)
chr11_+_59522837 0.29 ENST00000437946.2
syntaxin 3
chr19_-_51523275 0.29 ENST00000309958.3
kallikrein-related peptidase 10
chr19_-_44174330 0.29 ENST00000340093.3
plasminogen activator, urokinase receptor
chr5_+_169931009 0.29 ENST00000328939.4
ENST00000390656.4
Kv channel interacting protein 1
chr10_-_118928543 0.29 ENST00000419373.2
RP11-501J20.2
chr22_-_37584321 0.29 ENST00000397110.2
ENST00000337843.2
C1q and tumor necrosis factor related protein 6
chr6_-_32191834 0.28 ENST00000375023.3
notch 4
chr1_-_51796987 0.28 ENST00000262676.5
tetratricopeptide repeat domain 39A
chr17_-_27503770 0.28 ENST00000533112.1
myosin XVIIIA
chr14_+_103800513 0.28 ENST00000560338.1
ENST00000560763.1
ENST00000558316.1
ENST00000558265.1
eukaryotic translation initiation factor 5
chr20_+_30946106 0.27 ENST00000375687.4
ENST00000542461.1
additional sex combs like 1 (Drosophila)
chr20_+_4667094 0.27 ENST00000424424.1
ENST00000457586.1
prion protein
chr17_+_74381343 0.27 ENST00000392496.3
sphingosine kinase 1
chr7_+_150688083 0.27 ENST00000297494.3
nitric oxide synthase 3 (endothelial cell)
chr8_-_59572093 0.27 ENST00000427130.2
neutral sphingomyelinase (N-SMase) activation associated factor
chr11_+_57308979 0.27 ENST00000457912.1
smoothelin-like 1
chr11_-_62323702 0.27 ENST00000530285.1
AHNAK nucleoprotein
chr1_-_21059029 0.27 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2 domain containing 5
chr12_+_10365404 0.27 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr2_-_175712270 0.27 ENST00000295497.7
ENST00000444394.1
chimerin 1
chr1_+_222988464 0.27 ENST00000420335.1
RP11-452F19.3
chr17_+_35851570 0.26 ENST00000394386.1
dual specificity phosphatase 14
chr19_+_41949054 0.26 ENST00000378187.2
chromosome 19 open reading frame 69
chrX_+_135251783 0.26 ENST00000394153.2
four and a half LIM domains 1
chr6_-_35888824 0.26 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr10_-_21463116 0.26 ENST00000417816.2
nebulette
chrX_-_65253506 0.25 ENST00000427538.1
V-set and immunoglobulin domain containing 4
chr8_-_145025044 0.25 ENST00000322810.4
plectin
chr8_-_27472198 0.25 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
clusterin
chr4_+_76481258 0.25 ENST00000311623.4
ENST00000435974.2
chromosome 4 open reading frame 26
chr2_+_89890533 0.25 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr3_-_98241358 0.25 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
claudin domain containing 1
chr6_+_151042224 0.25 ENST00000358517.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr6_-_35888905 0.25 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr3_-_142720267 0.25 ENST00000597953.1
RP11-91G21.1
chr7_-_130598059 0.24 ENST00000432045.2
microRNA 29a
chr17_-_73781567 0.24 ENST00000586607.1
H3 histone, family 3B (H3.3B)
chr19_-_44008863 0.24 ENST00000601646.1
pleckstrin homology-like domain, family B, member 3
chr11_+_66742742 0.24 ENST00000308963.4
chromosome 11 open reading frame 86
chrX_-_150067069 0.24 ENST00000466436.1
CD99 molecule-like 2
chr1_-_111148241 0.24 ENST00000440270.1
potassium voltage-gated channel, shaker-related subfamily, member 2
chr2_-_89340242 0.24 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr3_+_5020801 0.24 ENST00000256495.3
basic helix-loop-helix family, member e40
chr8_+_104384616 0.23 ENST00000520337.1
collagen triple helix repeat containing 1
chr11_+_66360665 0.23 ENST00000310190.4
copper chaperone for superoxide dismutase
chr3_+_50284321 0.23 ENST00000451956.1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr7_+_55177416 0.23 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr12_+_56862301 0.23 ENST00000338146.5
SPRY domain containing 4
chr12_-_39836772 0.23 ENST00000541463.2
ENST00000361418.5
ENST00000544797.2
kinesin family member 21A

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
1.0 2.9 GO:0072019 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.5 1.8 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.4 1.5 GO:0006218 uridine catabolic process(GO:0006218)
0.4 1.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 0.9 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.3 2.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 2.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 0.7 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 2.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.7 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 0.6 GO:0034146 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) negative regulation of osteoclast proliferation(GO:0090291)
0.2 0.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.4 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.2 1.9 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2 1.1 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.2 1.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.2 0.7 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 2.6 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.6 GO:0035425 autocrine signaling(GO:0035425)
0.1 1.0 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.4 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740) smooth muscle hyperplasia(GO:0014806)
0.1 0.4 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.7 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.1 0.4 GO:0048627 myoblast development(GO:0048627)
0.1 0.8 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.4 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.7 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.6 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.8 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.4 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.4 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.3 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.3 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.4 GO:0002086 diaphragm contraction(GO:0002086)
0.1 1.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.4 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.3 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.7 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.4 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.4 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.3 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.1 0.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.5 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1 0.4 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.4 GO:0001554 luteolysis(GO:0001554)
0.1 0.2 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 0.5 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 1.0 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.6 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.3 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.1 0.7 GO:0042940 D-amino acid transport(GO:0042940)
0.1 0.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.2 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.1 0.5 GO:0051414 response to cortisol(GO:0051414)
0.1 0.3 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.2 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.2 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.2 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 0.2 GO:0060545 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 0.2 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.1 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.8 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0021764 amygdala development(GO:0021764) regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.0 0.6 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.7 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.2 GO:1902996 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484) response to L-ascorbic acid(GO:0033591) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:1901094 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.7 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099) pilomotor reflex(GO:0097195)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 1.9 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0086098 angiotensin-activated signaling pathway involved in heart process(GO:0086098)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.5 GO:0002251 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.0 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.3 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.0 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
0.0 0.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.0 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.5 GO:0003016 respiratory system process(GO:0003016)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.7 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.3 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.0 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.0 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.5 GO:0071451 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.0 0.8 GO:0006968 cellular defense response(GO:0006968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.7 5.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.5 1.8 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 0.7 GO:0097444 spine apparatus(GO:0097444)
0.2 0.7 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 0.5 GO:0044753 amphisome(GO:0044753)
0.2 0.6 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.5 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.3 GO:0071159 NF-kappaB complex(GO:0071159)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.9 GO:0097342 ripoptosome(GO:0097342)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 1.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 1.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.0 4.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 2.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.1 GO:0000922 spindle pole(GO:0000922)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
1.0 2.9 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.6 1.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 1.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.2 2.7 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2 0.9 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 1.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.7 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 1.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 1.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.6 GO:0031711 bradykinin receptor binding(GO:0031711)
0.1 0.3 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.2 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 1.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 4.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 4.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 3.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 5.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 3.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction