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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FOXA1

Z-value: 0.62

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Transcription factors associated with FOXA1

Gene Symbol Gene ID Gene Info
FOXA1
ENSG00000129514.4 forkhead box A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA1hg19_v2_chr14_-_38064198_38064239-0.116.0e-01Click!

Activity profile of FOXA1 motif

Sorted Z-values of FOXA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_18496957 1.18 ENST00000252809.3
GDF15
growth differentiation factor 15
chr2_+_150187020 1.07 ENST00000334166.4
LYPD6
LY6/PLAUR domain containing 6
chr22_+_21128167 0.88 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr18_+_3449330 0.82 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr9_+_126131131 0.76 ENST00000373629.2
CRB2
crumbs homolog 2 (Drosophila)
chr10_-_90751038 0.70 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr11_-_108464465 0.69 ENST00000525344.1
EXPH5
exophilin 5
chr1_-_111743285 0.68 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr1_-_201096312 0.66 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr17_+_74372662 0.66 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr10_+_91092241 0.66 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr8_+_120079478 0.65 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr3_-_145878954 0.64 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr1_+_101361782 0.64 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr5_+_156712372 0.63 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr6_-_31550192 0.62 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr15_+_28624878 0.54 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr15_+_60296421 0.53 ENST00000396057.4
FOXB1
forkhead box B1
chr11_-_9286921 0.51 ENST00000328194.3
DENND5A
DENN/MADD domain containing 5A
chr5_+_149980622 0.51 ENST00000394243.1
SYNPO
synaptopodin
chr7_-_71868354 0.50 ENST00000412588.1
CALN1
calneuron 1
chr15_+_71389281 0.47 ENST00000355327.3
THSD4
thrombospondin, type I, domain containing 4
chr6_-_89927151 0.45 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr2_+_202937972 0.45 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr15_-_55541227 0.43 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr20_+_52105495 0.42 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr2_-_152146385 0.42 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr17_-_39684550 0.41 ENST00000455635.1
ENST00000361566.3
KRT19
keratin 19
chr5_+_161494770 0.41 ENST00000414552.2
ENST00000361925.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr5_+_161494521 0.41 ENST00000356592.3
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr11_+_107799118 0.41 ENST00000320578.2
RAB39A
RAB39A, member RAS oncogene family
chr6_+_53883790 0.40 ENST00000509997.1
MLIP
muscular LMNA-interacting protein
chr2_-_69180012 0.40 ENST00000481498.1
GKN2
gastrokine 2
chr4_+_55095264 0.40 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr4_+_165675269 0.39 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr18_-_25616519 0.38 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr6_+_31582961 0.38 ENST00000376059.3
ENST00000337917.7
AIF1
allograft inflammatory factor 1
chr1_+_204839959 0.38 ENST00000404076.1
NFASC
neurofascin
chr5_+_161495038 0.38 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr6_+_135502501 0.36 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr17_+_8924837 0.36 ENST00000173229.2
NTN1
netrin 1
chr6_+_7108210 0.36 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1
ras responsive element binding protein 1
chr4_-_70080449 0.36 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr3_+_148447887 0.35 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr6_+_7107830 0.35 ENST00000379933.3
RREB1
ras responsive element binding protein 1
chr6_+_53883708 0.33 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP
muscular LMNA-interacting protein
chrX_+_150345054 0.32 ENST00000218316.3
GPR50
G protein-coupled receptor 50
chr1_+_223101757 0.31 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr2_+_42104692 0.31 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chr1_+_86934526 0.31 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr6_+_7107999 0.30 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chrX_+_9431324 0.30 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr4_-_72649763 0.30 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr17_-_26695013 0.30 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr17_-_26694979 0.29 ENST00000438614.1
VTN
vitronectin
chr11_-_108464321 0.29 ENST00000265843.4
EXPH5
exophilin 5
chr6_-_39290744 0.29 ENST00000507712.1
KCNK16
potassium channel, subfamily K, member 16
chr7_-_112579869 0.28 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr11_+_35684288 0.28 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr9_-_89562104 0.28 ENST00000298743.7
GAS1
growth arrest-specific 1
chr6_+_101847105 0.27 ENST00000369137.3
ENST00000318991.6
GRIK2
glutamate receptor, ionotropic, kainate 2
chr17_-_48546324 0.27 ENST00000508540.1
CHAD
chondroadherin
chr4_+_86396265 0.27 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr3_-_71632894 0.27 ENST00000493089.1
FOXP1
forkhead box P1
chr4_+_165675197 0.26 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr17_-_46035187 0.26 ENST00000300557.2
PRR15L
proline rich 15-like
chr4_-_186456652 0.26 ENST00000284767.5
ENST00000284770.5
PDLIM3
PDZ and LIM domain 3
chr3_+_189349162 0.25 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr2_+_169757750 0.25 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2
glucose-6-phosphatase, catalytic, 2
chr6_+_37897735 0.25 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr3_+_52245458 0.25 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr6_-_161085291 0.25 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr3_-_186080012 0.24 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr2_-_69180083 0.24 ENST00000328895.4
GKN2
gastrokine 2
chr6_-_43596899 0.24 ENST00000307126.5
ENST00000452781.1
GTPBP2
GTP binding protein 2
chr2_+_105050794 0.24 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr4_-_186456766 0.24 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr14_-_21493649 0.24 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2
NDRG family member 2
chrX_+_22050546 0.24 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr8_+_126442563 0.23 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr5_+_95998746 0.23 ENST00000508608.1
CAST
calpastatin
chr14_-_57272366 0.23 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr20_-_7921090 0.23 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr9_-_14722715 0.23 ENST00000380911.3
CER1
cerberus 1, DAN family BMP antagonist
chr14_-_21493884 0.23 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2
NDRG family member 2
chr19_-_15443318 0.23 ENST00000360016.5
BRD4
bromodomain containing 4
chr2_-_219850277 0.23 ENST00000295727.1
FEV
FEV (ETS oncogene family)
chr5_+_40841276 0.22 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr17_-_48546232 0.22 ENST00000258969.4
CHAD
chondroadherin
chr1_+_74701062 0.22 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr12_+_10658489 0.22 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr1_-_57431679 0.22 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
C8B
complement component 8, beta polypeptide
chr11_-_116663127 0.22 ENST00000433069.1
ENST00000542499.1
APOA5
apolipoprotein A-V
chr5_-_41213607 0.22 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr10_+_123923105 0.22 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr2_-_21266935 0.22 ENST00000233242.1
APOB
apolipoprotein B
chr19_+_42806250 0.21 ENST00000598490.1
ENST00000341747.3
PRR19
proline rich 19
chr10_-_75676400 0.21 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr6_+_33589161 0.21 ENST00000605930.1
ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chr12_+_121416437 0.21 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1A
HNF1 homeobox A
chr6_-_87804815 0.20 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr13_-_46716969 0.20 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_121416489 0.20 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr20_+_44420617 0.20 ENST00000449078.1
ENST00000456939.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr14_-_31926623 0.20 ENST00000356180.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr20_+_44420570 0.20 ENST00000372622.3
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr4_-_164534657 0.19 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr10_-_73848086 0.19 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr12_+_121416340 0.19 ENST00000257555.6
ENST00000400024.2
HNF1A
HNF1 homeobox A
chr14_-_31926701 0.19 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr1_+_43855545 0.19 ENST00000372450.4
ENST00000310739.4
SZT2
seizure threshold 2 homolog (mouse)
chr1_-_177939348 0.19 ENST00000464631.2
SEC16B
SEC16 homolog B (S. cerevisiae)
chr2_-_172290482 0.18 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
METTL8
methyltransferase like 8
chr7_+_129906660 0.18 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr12_-_102872317 0.18 ENST00000424202.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chrX_+_135614293 0.18 ENST00000370634.3
VGLL1
vestigial like 1 (Drosophila)
chr11_+_120973375 0.18 ENST00000264037.2
TECTA
tectorin alpha
chr16_+_7382745 0.17 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_-_137674000 0.17 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr3_-_190167571 0.17 ENST00000354905.2
TMEM207
transmembrane protein 207
chr1_-_43855444 0.17 ENST00000372455.4
MED8
mediator complex subunit 8
chr6_+_112375462 0.17 ENST00000361714.1
WISP3
WNT1 inducible signaling pathway protein 3
chr13_+_50589390 0.17 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chr22_-_40929812 0.17 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr14_+_105267250 0.17 ENST00000342537.7
ZBTB42
zinc finger and BTB domain containing 42
chr21_+_33671160 0.16 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr10_+_50507181 0.16 ENST00000323868.4
C10orf71
chromosome 10 open reading frame 71
chr22_-_45404819 0.16 ENST00000447824.3
ENST00000404079.2
ENST00000420689.1
ENST00000403565.1
PHF21B
PHD finger protein 21B
chr21_-_43771226 0.16 ENST00000291526.4
TFF2
trefoil factor 2
chr3_+_98072698 0.16 ENST00000354924.2
OR5K4
olfactory receptor, family 5, subfamily K, member 4
chr1_-_207095212 0.16 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr10_+_50507232 0.15 ENST00000374144.3
C10orf71
chromosome 10 open reading frame 71
chr1_-_207095324 0.15 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr2_+_58655461 0.15 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr18_+_70536215 0.15 ENST00000578967.1
RP11-676J15.1
RP11-676J15.1
chr3_-_45957534 0.15 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr2_+_172950227 0.15 ENST00000341900.6
DLX1
distal-less homeobox 1
chr7_+_106505696 0.15 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr10_+_118350468 0.15 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr11_+_57308979 0.15 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr14_+_23654525 0.14 ENST00000399910.1
ENST00000492621.1
C14orf164
chromosome 14 open reading frame 164
chr11_+_71249071 0.14 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr3_+_108321623 0.14 ENST00000497905.1
ENST00000463306.1
DZIP3
DAZ interacting zinc finger protein 3
chr7_-_107443652 0.14 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr11_+_66025938 0.14 ENST00000394066.2
KLC2
kinesin light chain 2
chr6_+_1080164 0.14 ENST00000314040.1
AL033381.1
Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
chr4_+_187187098 0.13 ENST00000403665.2
ENST00000264692.4
F11
coagulation factor XI
chr3_+_174577070 0.13 ENST00000454872.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr8_-_116681221 0.13 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr3_-_45957088 0.13 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr12_-_21487829 0.13 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr9_+_136287444 0.12 ENST00000355699.2
ENST00000356589.2
ENST00000371911.3
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr16_-_86542455 0.12 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FENDRR
FOXF1 adjacent non-coding developmental regulatory RNA
chr8_+_77593474 0.12 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr6_+_54172653 0.12 ENST00000370869.3
TINAG
tubulointerstitial nephritis antigen
chr1_+_214161854 0.12 ENST00000435016.1
PROX1
prospero homeobox 1
chr10_+_18689637 0.12 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr4_-_174256276 0.12 ENST00000296503.5
HMGB2
high mobility group box 2
chr17_+_9728828 0.12 ENST00000262441.5
GLP2R
glucagon-like peptide 2 receptor
chr19_-_45909585 0.12 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr1_-_246729544 0.12 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr16_-_87970122 0.12 ENST00000309893.2
CA5A
carbonic anhydrase VA, mitochondrial
chr6_+_112375275 0.12 ENST00000368666.2
ENST00000604763.1
ENST00000230529.5
WISP3
WNT1 inducible signaling pathway protein 3
chr3_-_120068143 0.12 ENST00000295628.3
LRRC58
leucine rich repeat containing 58
chr1_-_178840157 0.12 ENST00000367629.1
ENST00000234816.2
ANGPTL1
angiopoietin-like 1
chr4_+_55095428 0.11 ENST00000508170.1
ENST00000512143.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr2_+_179345173 0.11 ENST00000234453.5
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr12_-_48398104 0.11 ENST00000337299.6
ENST00000380518.3
COL2A1
collagen, type II, alpha 1
chr13_-_86373536 0.11 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr16_+_73420942 0.11 ENST00000554640.1
ENST00000562661.1
ENST00000561875.1
RP11-140I24.1
RP11-140I24.1
chr8_+_87878640 0.11 ENST00000518476.1
CNBD1
cyclic nucleotide binding domain containing 1
chr2_-_182545603 0.11 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr10_+_102891048 0.11 ENST00000467928.2
TLX1
T-cell leukemia homeobox 1
chr8_+_77593448 0.11 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr7_+_106505912 0.10 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr14_+_37126765 0.10 ENST00000402703.2
PAX9
paired box 9
chr6_-_90025011 0.10 ENST00000402938.3
GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr17_+_36873677 0.10 ENST00000471200.1
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr14_+_23299088 0.10 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr9_+_140125385 0.10 ENST00000361134.2
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr2_-_121223697 0.10 ENST00000593290.1
FLJ14816
long intergenic non-protein coding RNA 1101
chr2_+_152266604 0.10 ENST00000430328.2
RIF1
RAP1 interacting factor homolog (yeast)
chr12_-_52828147 0.10 ENST00000252245.5
KRT75
keratin 75
chr7_+_77325738 0.09 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chrX_-_47863348 0.09 ENST00000376943.3
ENST00000396965.1
ENST00000305127.6
ZNF182
zinc finger protein 182
chrX_-_111923145 0.09 ENST00000371968.3
ENST00000536453.1
LHFPL1
lipoma HMGIC fusion partner-like 1
chr1_-_232651312 0.09 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr1_-_43855479 0.09 ENST00000290663.6
ENST00000372457.4
MED8
mediator complex subunit 8
chr7_-_81399355 0.09 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_+_28452130 0.09 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr7_-_81399411 0.09 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr2_+_162101247 0.09 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr1_-_11107280 0.09 ENST00000400897.3
ENST00000400898.3
MASP2
mannan-binding lectin serine peptidase 2
chr6_+_10528560 0.09 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr6_-_90024967 0.09 ENST00000602399.1
GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr6_-_88875654 0.08 ENST00000535130.1
CNR1
cannabinoid receptor 1 (brain)
chr9_-_14910420 0.08 ENST00000380880.3
FREM1
FRAS1 related extracellular matrix 1
chr5_-_148758839 0.08 ENST00000261796.3
IL17B
interleukin 17B
chr9_+_6413317 0.08 ENST00000276893.5
ENST00000381373.3
UHRF2
ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
chr1_-_27240455 0.08 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 0.7 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.6 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 0.6 GO:0035565 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.2 0.5 GO:0007412 axon target recognition(GO:0007412)
0.1 0.5 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.8 GO:0014028 notochord formation(GO:0014028)
0.1 0.5 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.9 GO:0008218 bioluminescence(GO:0008218)
0.1 0.5 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 0.7 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.3 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.4 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.2 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.6 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.4 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 1.2 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.0 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:1902871 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 1.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0032252 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.0 0.1 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0034371 triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269) chylomicron remodeling(GO:0034371)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.1 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.0 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:1900104 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme morphogenesis(GO:0072134) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) allantois development(GO:1905069)
0.0 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 1.1 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.2 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.5 GO:0050982 detection of mechanical stimulus(GO:0050982)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0097444 spine apparatus(GO:0097444)
0.1 0.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 1.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 0.6 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.4 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.8 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.7 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.4 GO:0035473 lipase binding(GO:0035473)
0.1 0.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.8 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.3 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade