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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FOXA3_FOXC2

Z-value: 0.59

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Transcription factors associated with FOXA3_FOXC2

Gene Symbol Gene ID Gene Info
FOXA3
ENSG00000170608.2 forkhead box A3
FOXC2
ENSG00000176692.4 forkhead box C2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXC2hg19_v2_chr16_+_86600857_86600921-0.462.0e-02Click!
FOXA3hg19_v2_chr19_+_46367518_463675670.331.1e-01Click!

Activity profile of FOXA3_FOXC2 motif

Sorted Z-values of FOXA3_FOXC2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_120079478 1.68 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr11_-_108464465 1.56 ENST00000525344.1
EXPH5
exophilin 5
chr7_+_151038850 1.05 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr1_+_74701062 1.00 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr1_-_201096312 0.98 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr5_+_156712372 0.96 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chrX_-_15402498 0.86 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr20_+_9494987 0.84 ENST00000427562.2
ENST00000246070.2
LAMP5
lysosomal-associated membrane protein family, member 5
chr8_+_104384616 0.82 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chrX_+_9431324 0.76 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr10_+_71561649 0.75 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr1_-_57431679 0.72 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
C8B
complement component 8, beta polypeptide
chr10_+_71561704 0.67 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr17_-_29641084 0.66 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr11_+_62186498 0.62 ENST00000278282.2
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr1_+_101361782 0.61 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr2_+_162272605 0.61 ENST00000389554.3
TBR1
T-box, brain, 1
chr20_+_52105495 0.59 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr10_+_71561630 0.58 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr11_+_20044096 0.57 ENST00000533917.1
NAV2
neuron navigator 2
chr1_-_207095212 0.57 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr4_-_70826725 0.56 ENST00000353151.3
CSN2
casein beta
chr17_+_74372662 0.56 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr2_-_175711133 0.55 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr22_+_21128167 0.54 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr11_-_108464321 0.51 ENST00000265843.4
EXPH5
exophilin 5
chr3_+_108855558 0.50 ENST00000467240.1
ENST00000477643.1
ENST00000479039.1
ENST00000593799.1
RP11-59E19.1
RP11-59E19.1
chr1_-_207095324 0.46 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr4_-_164534657 0.45 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr6_+_37897735 0.45 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr2_+_58655461 0.43 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr6_-_87804815 0.42 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr18_-_25616519 0.42 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr5_-_137674000 0.42 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr7_-_115670804 0.41 ENST00000320239.7
TFEC
transcription factor EC
chr3_-_116163830 0.40 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr4_+_169013666 0.39 ENST00000359299.3
ANXA10
annexin A10
chr9_-_14722715 0.39 ENST00000380911.3
CER1
cerberus 1, DAN family BMP antagonist
chr3_+_69985792 0.38 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr16_-_87970122 0.37 ENST00000309893.2
CA5A
carbonic anhydrase VA, mitochondrial
chr10_+_70847852 0.37 ENST00000242465.3
SRGN
serglycin
chr4_+_79567314 0.36 ENST00000503539.1
ENST00000504675.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr18_+_3449330 0.35 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr5_-_58571935 0.35 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_186080012 0.32 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr3_+_50712672 0.32 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr1_-_169555779 0.31 ENST00000367797.3
ENST00000367796.3
F5
coagulation factor V (proaccelerin, labile factor)
chr4_-_70080449 0.31 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr1_+_239882842 0.31 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr3_-_107941209 0.31 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr10_+_71562180 0.30 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr3_+_130569429 0.30 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr3_+_148447887 0.30 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr3_+_130569592 0.30 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr11_-_85397167 0.29 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr2_+_113885138 0.29 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr4_+_79567362 0.29 ENST00000512322.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr7_+_134576317 0.28 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr3_-_71294304 0.28 ENST00000498215.1
FOXP1
forkhead box P1
chr7_+_86273218 0.28 ENST00000361669.2
GRM3
glutamate receptor, metabotropic 3
chr6_-_161085291 0.28 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr1_-_152332480 0.27 ENST00000388718.5
FLG2
filaggrin family member 2
chr10_-_4285923 0.27 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr4_-_123377880 0.27 ENST00000226730.4
IL2
interleukin 2
chr7_-_81399411 0.27 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr2_+_105050794 0.27 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr7_-_22259845 0.26 ENST00000420196.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr6_+_21666633 0.26 ENST00000606851.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr5_+_95998746 0.26 ENST00000508608.1
CAST
calpastatin
chr16_-_48281305 0.25 ENST00000356608.2
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr11_+_119205222 0.25 ENST00000311413.4
RNF26
ring finger protein 26
chr11_-_116708302 0.25 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1
apolipoprotein A-I
chr5_+_140529630 0.25 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr7_-_141673573 0.25 ENST00000547270.1
TAS2R38
taste receptor, type 2, member 38
chr4_+_89206076 0.24 ENST00000500009.2
RP11-10L7.1
RP11-10L7.1
chr17_-_39684550 0.24 ENST00000455635.1
ENST00000361566.3
KRT19
keratin 19
chr1_+_86934526 0.24 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr15_+_69857515 0.24 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr3_+_114012819 0.24 ENST00000383671.3
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr7_+_134430212 0.23 ENST00000436461.2
CALD1
caldesmon 1
chr11_-_66112555 0.23 ENST00000425825.2
ENST00000359957.3
BRMS1
breast cancer metastasis suppressor 1
chr12_-_18243119 0.23 ENST00000538724.1
ENST00000229002.2
RERGL
RERG/RAS-like
chr4_-_174256276 0.22 ENST00000296503.5
HMGB2
high mobility group box 2
chr5_+_161494770 0.22 ENST00000414552.2
ENST00000361925.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr20_+_9049682 0.22 ENST00000334005.3
ENST00000378473.3
PLCB4
phospholipase C, beta 4
chr2_-_180427304 0.22 ENST00000336917.5
ZNF385B
zinc finger protein 385B
chr15_+_71185148 0.22 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr18_+_61575200 0.22 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr5_-_59481406 0.21 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_172290482 0.21 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
METTL8
methyltransferase like 8
chr13_-_86373536 0.21 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr6_+_44310421 0.21 ENST00000288390.2
SPATS1
spermatogenesis associated, serine-rich 1
chr10_-_31288398 0.20 ENST00000538351.2
ZNF438
zinc finger protein 438
chr3_-_107941230 0.20 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr6_+_44310376 0.20 ENST00000515220.1
ENST00000323108.8
SPATS1
spermatogenesis associated, serine-rich 1
chr1_-_43855444 0.20 ENST00000372455.4
MED8
mediator complex subunit 8
chr5_+_140710061 0.20 ENST00000517417.1
ENST00000378105.3
PCDHGA1
protocadherin gamma subfamily A, 1
chr20_-_1974692 0.20 ENST00000217305.2
ENST00000539905.1
PDYN
prodynorphin
chr11_-_72070206 0.19 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr15_+_58430368 0.19 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr2_-_175260368 0.19 ENST00000342016.3
ENST00000362053.5
CIR1
corepressor interacting with RBPJ, 1
chr14_-_70263979 0.19 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr1_+_172389821 0.19 ENST00000367727.4
C1orf105
chromosome 1 open reading frame 105
chr7_-_107443652 0.19 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr1_-_167522982 0.19 ENST00000370509.4
CREG1
cellular repressor of E1A-stimulated genes 1
chr18_+_21033239 0.19 ENST00000581585.1
ENST00000577501.1
RIOK3
RIO kinase 3
chr12_-_21487829 0.19 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr5_+_161494521 0.19 ENST00000356592.3
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr4_-_87028478 0.19 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr18_-_3874752 0.18 ENST00000534970.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr17_+_56232494 0.18 ENST00000268912.5
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr15_+_58430567 0.18 ENST00000536493.1
AQP9
aquaporin 9
chr17_+_79953310 0.18 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr7_+_123241908 0.18 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr12_-_39734783 0.18 ENST00000552961.1
KIF21A
kinesin family member 21A
chr14_-_21562648 0.18 ENST00000555270.1
ZNF219
zinc finger protein 219
chr10_-_118032697 0.18 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr6_-_43596899 0.18 ENST00000307126.5
ENST00000452781.1
GTPBP2
GTP binding protein 2
chr5_-_41213607 0.18 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr12_-_21927736 0.18 ENST00000240662.2
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr8_-_95449155 0.17 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr14_+_23299088 0.17 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr12_-_53207842 0.17 ENST00000458244.2
KRT4
keratin 4
chr3_-_196910721 0.17 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr17_-_39471947 0.17 ENST00000334202.3
KRTAP17-1
keratin associated protein 17-1
chr5_+_40841276 0.17 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr6_+_125524785 0.17 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chrX_+_99839799 0.17 ENST00000373031.4
TNMD
tenomodulin
chr10_+_123923105 0.16 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr3_+_119316689 0.16 ENST00000273371.4
PLA1A
phospholipase A1 member A
chr4_+_15376165 0.16 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr18_-_3874247 0.16 ENST00000581699.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr7_+_134464376 0.16 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr14_-_99737565 0.16 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr1_+_43855560 0.16 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr5_+_135468516 0.16 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chr13_+_50589390 0.16 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chr10_-_21435488 0.15 ENST00000534331.1
ENST00000529198.1
ENST00000377118.4
C10orf113
chromosome 10 open reading frame 113
chr7_-_121944491 0.15 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr20_-_7921090 0.15 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr3_+_119316721 0.15 ENST00000488919.1
ENST00000495992.1
PLA1A
phospholipase A1 member A
chr5_-_115872142 0.15 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_+_171561127 0.15 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr1_-_28384598 0.15 ENST00000373864.1
EYA3
eyes absent homolog 3 (Drosophila)
chr22_+_46449674 0.15 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr17_-_19290483 0.15 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr12_-_76879852 0.15 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr10_-_71176623 0.15 ENST00000373306.4
TACR2
tachykinin receptor 2
chr7_+_129847688 0.15 ENST00000297819.3
SSMEM1
serine-rich single-pass membrane protein 1
chr14_+_52164820 0.14 ENST00000554167.1
FRMD6
FERM domain containing 6
chr17_-_39324424 0.14 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr1_+_152486950 0.14 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr7_+_112063192 0.14 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chrX_+_23352133 0.14 ENST00000379361.4
PTCHD1
patched domain containing 1
chr3_+_189349162 0.14 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr17_-_26695013 0.14 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr14_-_99737822 0.14 ENST00000345514.2
ENST00000443726.2
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr3_+_69985734 0.13 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr10_+_124739911 0.13 ENST00000405485.1
PSTK
phosphoseryl-tRNA kinase
chr6_+_31582961 0.13 ENST00000376059.3
ENST00000337917.7
AIF1
allograft inflammatory factor 1
chr7_+_28452130 0.13 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr18_-_3874271 0.13 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr10_-_75676400 0.13 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr1_-_43855479 0.13 ENST00000290663.6
ENST00000372457.4
MED8
mediator complex subunit 8
chr17_-_26694979 0.13 ENST00000438614.1
VTN
vitronectin
chr5_-_24645078 0.13 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr4_-_21950356 0.13 ENST00000447367.2
ENST00000382152.2
KCNIP4
Kv channel interacting protein 4
chr11_-_83984231 0.12 ENST00000330014.6
ENST00000537455.1
ENST00000376106.3
ENST00000418306.2
ENST00000531015.1
DLG2
discs, large homolog 2 (Drosophila)
chr1_+_244214577 0.12 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr13_+_73629107 0.12 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr11_-_124180733 0.12 ENST00000357821.2
OR8D1
olfactory receptor, family 8, subfamily D, member 1
chr2_-_208030647 0.12 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr14_-_57272366 0.12 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr13_-_36429763 0.12 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr4_+_184826418 0.12 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr2_+_128175997 0.12 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr17_-_29641104 0.11 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr17_+_8924837 0.11 ENST00000173229.2
NTN1
netrin 1
chr8_-_23261589 0.11 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2
lysyl oxidase-like 2
chr16_-_86542455 0.11 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FENDRR
FOXF1 adjacent non-coding developmental regulatory RNA
chr6_+_10528560 0.11 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr7_+_134464414 0.11 ENST00000361901.2
CALD1
caldesmon 1
chr3_+_155588375 0.11 ENST00000295920.7
GMPS
guanine monphosphate synthase
chr4_+_15341442 0.11 ENST00000397700.2
ENST00000295297.4
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr17_+_7487146 0.11 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr16_+_84801852 0.11 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr14_+_58711539 0.11 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr21_-_32931290 0.11 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr20_-_55841398 0.11 ENST00000395864.3
BMP7
bone morphogenetic protein 7
chr10_+_124739964 0.10 ENST00000406217.2
PSTK
phosphoseryl-tRNA kinase
chr5_+_60933634 0.10 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr14_+_105267250 0.10 ENST00000342537.7
ZBTB42
zinc finger and BTB domain containing 42
chr1_-_150669500 0.10 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr2_+_175260514 0.10 ENST00000424069.1
ENST00000427038.1
SCRN3
secernin 3
chr6_-_25830785 0.10 ENST00000468082.1
SLC17A1
solute carrier family 17 (organic anion transporter), member 1
chr21_-_36259445 0.10 ENST00000399240.1
RUNX1
runt-related transcription factor 1
chr6_-_168479839 0.10 ENST00000283309.6
FRMD1
FERM domain containing 1
chr12_+_93096759 0.10 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr4_+_165675269 0.10 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr2_+_169659121 0.10 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN
nitric oxide synthase trafficking

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA3_FOXC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1903487 regulation of lactation(GO:1903487)
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.2 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 1.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.4 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.8 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.6 GO:0010193 response to ozone(GO:0010193)
0.1 2.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.6 GO:0021764 amygdala development(GO:0021764)
0.1 0.6 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 1.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.6 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.4 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.3 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.2 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) operant conditioning(GO:0035106)
0.0 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:1905069 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme morphogenesis(GO:0072134) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) allantois development(GO:1905069)
0.0 1.0 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 2.3 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.4 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.0 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0071493 elastic fiber assembly(GO:0048251) cellular response to UV-B(GO:0071493)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.5 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.8 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.2 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.5 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 0.0 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.4 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.6 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.0 GO:0031013 troponin I binding(GO:0031013)
0.1 0.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.7 GO:0005537 mannose binding(GO:0005537)
0.1 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.4 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.3 GO:0043208 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 2.2 GO:0008201 heparin binding(GO:0008201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters