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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FOXC1

Z-value: 0.84

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Transcription factors associated with FOXC1

Gene Symbol Gene ID Gene Info
FOXC1
ENSG00000054598.5 forkhead box C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXC1hg19_v2_chr6_+_1610681_16106810.573.1e-03Click!

Activity profile of FOXC1 motif

Sorted Z-values of FOXC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_93107443 5.32 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_186696425 4.33 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr4_-_102267953 3.72 ENST00000523694.2
ENST00000507176.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_+_61542922 2.97 ENST00000407417.3
NFIA
nuclear factor I/A
chr1_+_61547894 2.28 ENST00000403491.3
NFIA
nuclear factor I/A
chr1_-_100231349 2.27 ENST00000287474.5
ENST00000414213.1
FRRS1
ferric-chelate reductase 1
chr3_-_168865522 2.13 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr8_-_80993010 1.99 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr4_-_102268484 1.92 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_+_112631547 1.90 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr4_-_102268628 1.86 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr5_-_111091948 1.81 ENST00000447165.2
NREP
neuronal regeneration related protein
chr7_-_27219849 1.80 ENST00000396344.4
HOXA10
homeobox A10
chr16_-_88772670 1.80 ENST00000562544.1
RNF166
ring finger protein 166
chrX_-_117107680 1.66 ENST00000447671.2
ENST00000262820.3
KLHL13
kelch-like family member 13
chr8_+_97597148 1.64 ENST00000521590.1
SDC2
syndecan 2
chrX_-_117107542 1.57 ENST00000371878.1
KLHL13
kelch-like family member 13
chr8_-_93107696 1.51 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_52730143 1.48 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr9_+_71944241 1.36 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chrX_-_19688475 1.36 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr2_+_173686303 1.35 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr9_+_127054217 1.30 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6
chr17_-_46688334 1.30 ENST00000239165.7
HOXB7
homeobox B7
chr8_-_93107827 1.27 ENST00000520724.1
ENST00000518844.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_+_96869165 1.26 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr8_-_19540086 1.24 ENST00000332246.6
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chrX_+_54947229 1.23 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr9_-_86432547 1.22 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr21_+_17791648 1.17 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr6_-_42016385 1.17 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr18_-_53303123 1.16 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr4_-_99578776 1.13 ENST00000515287.1
TSPAN5
tetraspanin 5
chr6_+_18387570 1.11 ENST00000259939.3
RNF144B
ring finger protein 144B
chr5_-_39425222 1.11 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr5_-_39425290 1.09 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr5_-_39425068 1.08 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr4_-_99578789 1.07 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr19_+_17516909 1.04 ENST00000601007.1
ENST00000594913.1
ENST00000599975.1
ENST00000600514.1
CTD-2521M24.9
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
chr2_+_33359646 0.99 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr13_+_36050881 0.98 ENST00000537702.1
NBEA
neurobeachin
chr12_-_68696652 0.97 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr21_+_17791838 0.97 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr2_+_33359687 0.96 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr21_+_17792672 0.93 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr1_-_228135599 0.87 ENST00000272164.5
WNT9A
wingless-type MMTV integration site family, member 9A
chr9_+_134103496 0.84 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr4_-_89744457 0.82 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr1_-_94079648 0.79 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chrX_-_19689106 0.78 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr18_-_53070913 0.75 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr12_+_10365404 0.73 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr7_+_80231466 0.73 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr3_-_114343039 0.72 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_141868293 0.72 ENST00000317104.7
ENST00000494358.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr19_+_17516531 0.67 ENST00000528911.1
ENST00000528604.1
ENST00000595892.1
ENST00000500836.2
ENST00000598546.1
ENST00000600369.1
ENST00000598356.1
ENST00000594426.1
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
CTD-2521M24.9
chr19_-_40919271 0.66 ENST00000291825.7
ENST00000324001.7
PRX
periaxin
chr20_-_17511962 0.66 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr12_+_59989791 0.65 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr17_-_27503770 0.60 ENST00000533112.1
MYO18A
myosin XVIIIA
chr12_+_27175476 0.57 ENST00000546323.1
ENST00000282892.3
MED21
mediator complex subunit 21
chr6_+_119215308 0.56 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr1_+_12524965 0.56 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr16_+_2570340 0.53 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2
amidohydrolase domain containing 2
chr6_-_79787902 0.52 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr7_+_79998864 0.51 ENST00000435819.1
CD36
CD36 molecule (thrombospondin receptor)
chr8_+_70404996 0.50 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr8_+_11666649 0.50 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr4_+_147096837 0.49 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_181845843 0.49 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr5_-_55529115 0.48 ENST00000513241.2
ENST00000341048.4
ANKRD55
ankyrin repeat domain 55
chr19_-_36523709 0.47 ENST00000592017.1
ENST00000360535.4
CLIP3
CAP-GLY domain containing linker protein 3
chr12_+_43086018 0.47 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr7_-_14029283 0.47 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr6_+_32121789 0.46 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr3_-_141868357 0.46 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_151431647 0.46 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr6_+_32121908 0.45 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr14_-_74226961 0.45 ENST00000286523.5
ENST00000435371.1
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr8_-_145754428 0.44 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr10_+_54074033 0.44 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr11_-_6440624 0.44 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr15_+_42120283 0.43 ENST00000542534.2
ENST00000397299.4
ENST00000408047.1
ENST00000431823.1
ENST00000382448.4
ENST00000342159.4
PLA2G4B
JMJD7
JMJD7-PLA2G4B
phospholipase A2, group IVB (cytosolic)
jumonji domain containing 7
JMJD7-PLA2G4B readthrough
chr15_-_55657428 0.43 ENST00000568543.1
CCPG1
cell cycle progression 1
chr4_+_86396265 0.43 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr5_+_159614374 0.42 ENST00000393980.4
FABP6
fatty acid binding protein 6, ileal
chr11_+_34654011 0.42 ENST00000531794.1
EHF
ets homologous factor
chr22_+_46449674 0.41 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr20_-_35890211 0.41 ENST00000373614.2
GHRH
growth hormone releasing hormone
chr3_-_114477962 0.40 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_94312706 0.39 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr3_-_114477787 0.39 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_+_131438443 0.38 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr7_-_14028488 0.36 ENST00000405358.4
ETV1
ets variant 1
chr19_-_51141196 0.36 ENST00000338916.4
SYT3
synaptotagmin III
chr4_+_71588372 0.36 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr4_+_71587669 0.36 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr11_-_6440283 0.35 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr1_-_109935819 0.35 ENST00000538502.1
SORT1
sortilin 1
chr14_-_92572894 0.35 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3
chr15_+_76352178 0.33 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr4_+_129732467 0.33 ENST00000413543.2
PHF17
jade family PHD finger 1
chr12_+_122516626 0.33 ENST00000319080.7
MLXIP
MLX interacting protein
chr12_+_59989918 0.33 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr1_+_155099927 0.33 ENST00000368407.3
EFNA1
ephrin-A1
chr17_-_57229155 0.32 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr7_-_37026108 0.30 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr3_+_107096188 0.30 ENST00000261058.1
CCDC54
coiled-coil domain containing 54
chr4_+_76871883 0.29 ENST00000599764.1
AC110615.1
Uncharacterized protein
chr6_-_100442077 0.29 ENST00000281806.2
ENST00000369212.2
MCHR2
melanin-concentrating hormone receptor 2
chr19_-_4831701 0.29 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr6_-_32122106 0.29 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr12_+_16109519 0.28 ENST00000526530.1
DERA
deoxyribose-phosphate aldolase (putative)
chr1_-_151431909 0.28 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chr16_-_740419 0.28 ENST00000248142.6
WDR24
WD repeat domain 24
chr11_+_10477733 0.27 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr16_-_740354 0.27 ENST00000293883.4
WDR24
WD repeat domain 24
chr15_-_72563585 0.27 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr11_-_121986923 0.26 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr16_+_6069072 0.26 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_+_120590803 0.25 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chr12_-_29936731 0.25 ENST00000552618.1
ENST00000539277.1
ENST00000551659.1
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr14_-_20774092 0.25 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
TTC5
tetratricopeptide repeat domain 5
chr20_-_62587735 0.25 ENST00000354216.6
ENST00000369892.3
ENST00000358711.3
UCKL1
uridine-cytidine kinase 1-like 1
chr20_-_62582475 0.25 ENST00000369908.5
UCKL1
uridine-cytidine kinase 1-like 1
chr2_-_27886460 0.25 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr3_-_157221128 0.25 ENST00000392833.2
ENST00000362010.2
VEPH1
ventricular zone expressed PH domain-containing 1
chr13_-_61989655 0.24 ENST00000409204.4
PCDH20
protocadherin 20
chr6_-_39399087 0.24 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
KIF6
kinesin family member 6
chr3_-_178865747 0.24 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr16_+_6069586 0.23 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_+_159436120 0.22 ENST00000522793.1
ENST00000231238.5
TTC1
tetratricopeptide repeat domain 1
chr1_+_220701456 0.21 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr6_-_31651817 0.21 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr1_+_199996702 0.21 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr2_+_27886330 0.21 ENST00000326019.6
SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr20_-_34117447 0.21 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
C20orf173
chromosome 20 open reading frame 173
chr4_-_164534657 0.21 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr7_-_95064264 0.21 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
PON2
paraoxonase 2
chr9_-_136933134 0.21 ENST00000303407.7
BRD3
bromodomain containing 3
chr12_-_81763127 0.20 ENST00000541017.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr12_-_92539614 0.19 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr12_-_81763184 0.19 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr2_-_27886676 0.19 ENST00000337768.5
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr2_+_28974603 0.18 ENST00000441461.1
ENST00000358506.2
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr5_+_161495038 0.18 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr15_+_49462434 0.17 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
GALK2
galactokinase 2
chr3_+_142315225 0.16 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr3_+_46448648 0.16 ENST00000399036.3
CCRL2
chemokine (C-C motif) receptor-like 2
chr13_-_36429763 0.16 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr11_+_10476851 0.16 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr2_-_32490859 0.16 ENST00000404025.2
NLRC4
NLR family, CARD domain containing 4
chr10_+_114710211 0.16 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr15_-_30114622 0.15 ENST00000495972.2
ENST00000346128.6
TJP1
tight junction protein 1
chr5_+_40841276 0.15 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr17_-_39471947 0.15 ENST00000334202.3
KRTAP17-1
keratin associated protein 17-1
chrX_+_135730297 0.15 ENST00000370629.2
CD40LG
CD40 ligand
chr18_+_60382672 0.15 ENST00000400316.4
ENST00000262719.5
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr22_-_43036607 0.15 ENST00000505920.1
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chrX_+_135730373 0.15 ENST00000370628.2
CD40LG
CD40 ligand
chr12_-_122018346 0.14 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr11_-_790060 0.14 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr15_+_58430567 0.14 ENST00000536493.1
AQP9
aquaporin 9
chr7_+_139528952 0.13 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr9_-_139258159 0.13 ENST00000371739.3
DNLZ
DNL-type zinc finger
chr2_-_8977714 0.13 ENST00000319688.5
ENST00000489024.1
ENST00000256707.3
ENST00000427284.1
ENST00000418530.1
ENST00000473731.1
KIDINS220
kinase D-interacting substrate, 220kDa
chrX_+_99839799 0.13 ENST00000373031.4
TNMD
tenomodulin
chrX_+_100743031 0.13 ENST00000423738.3
ARMCX4
armadillo repeat containing, X-linked 4
chr22_+_41487711 0.13 ENST00000263253.7
EP300
E1A binding protein p300
chr3_+_48481658 0.13 ENST00000438607.2
TMA7
translation machinery associated 7 homolog (S. cerevisiae)
chr7_+_139529040 0.12 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr12_-_123756781 0.12 ENST00000544658.1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr15_+_58430368 0.12 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chrX_+_92929192 0.12 ENST00000332647.4
FAM133A
family with sequence similarity 133, member A
chr7_-_72972319 0.12 ENST00000223368.2
BCL7B
B-cell CLL/lymphoma 7B
chr5_+_179921344 0.11 ENST00000261951.4
CNOT6
CCR4-NOT transcription complex, subunit 6
chr13_+_27825706 0.11 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21
ribosomal protein L21
chr19_+_52848659 0.11 ENST00000327920.8
ZNF610
zinc finger protein 610
chr2_+_207024306 0.11 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr22_-_46659219 0.11 ENST00000253255.5
PKDREJ
polycystin (PKD) family receptor for egg jelly
chr1_-_19811132 0.11 ENST00000433834.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr7_+_123488124 0.10 ENST00000476325.1
HYAL4
hyaluronoglucosaminidase 4
chr3_-_133969673 0.10 ENST00000427044.2
RYK
receptor-like tyrosine kinase
chr1_+_22778337 0.09 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr5_+_112312416 0.09 ENST00000389063.2
DCP2
decapping mRNA 2
chr10_-_97200772 0.09 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chr16_+_22517166 0.09 ENST00000356156.3
NPIPB5
nuclear pore complex interacting protein family, member B5
chr1_-_159880159 0.09 ENST00000599780.1
AL590560.1
HCG1995379; Uncharacterized protein
chr7_-_42951509 0.09 ENST00000438029.1
ENST00000432637.1
ENST00000447342.1
ENST00000431882.2
ENST00000350427.4
ENST00000425683.1
C7orf25
chromosome 7 open reading frame 25
chr2_-_72374948 0.08 ENST00000546307.1
ENST00000474509.1
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr8_-_108510224 0.08 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr21_+_39628852 0.08 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr17_+_28268623 0.07 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5
EF-hand calcium binding domain 5
chr3_+_46449049 0.07 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
chemokine (C-C motif) receptor-like 2
chr22_-_39268308 0.07 ENST00000407418.3
CBX6
chromobox homolog 6
chr1_+_207277590 0.07 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr19_+_782755 0.07 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr5_-_127674883 0.07 ENST00000507835.1
FBN2
fibrillin 2
chr2_+_44502597 0.07 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr15_+_80351977 0.07 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.8 3.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.6 1.9 GO:0036446 myofibroblast differentiation(GO:0036446) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) regulation of myofibroblast differentiation(GO:1904760)
0.3 1.7 GO:0019075 virus maturation(GO:0019075)
0.3 1.3 GO:0009956 radial pattern formation(GO:0009956)
0.3 1.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.3 0.8 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.2 1.6 GO:0008218 bioluminescence(GO:0008218)
0.2 2.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.6 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 1.2 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 4.3 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0003129 heart induction(GO:0003129) regulation of endodermal cell fate specification(GO:0042663) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.4 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 4.3 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.0 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 6.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.5 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.9 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.3 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.9 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 1.0 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 1.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.3 GO:0003176 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.1 2.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.5 GO:0044211 CTP salvage(GO:0044211)
0.1 1.8 GO:0060065 uterus development(GO:0060065)
0.1 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.7 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.7 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 0.3 GO:0045359 positive regulation of chemokine biosynthetic process(GO:0045080) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 1.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 1.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 2.1 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.0 1.8 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 1.5 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:0016045 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 1.2 GO:0007566 embryo implantation(GO:0007566)
0.0 0.2 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 3.2 GO:0000910 cytokinesis(GO:0000910)
0.0 0.3 GO:0051023 regulation of immunoglobulin secretion(GO:0051023)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:1903027 regulation of opsonization(GO:1903027)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.5 GO:0005955 calcineurin complex(GO:0005955)
0.4 3.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 0.8 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 1.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 1.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.0 8.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 2.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.7 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 4.1 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 2.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4 1.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.4 1.9 GO:0050436 microfibril binding(GO:0050436)
0.4 2.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 1.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 1.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 4.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 3.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.5 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.4 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.3 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0097001 ceramide binding(GO:0097001)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.2 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 1.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 2.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 5.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 3.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 6.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 6.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 3.3 PID AURORA B PATHWAY Aurora B signaling
0.0 1.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 3.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 6.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 3.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 2.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 4.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network