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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 1.06

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Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Gene Symbol Gene ID Gene Info
ENSG00000251493.2 forkhead box D1
ENSG00000150907.6 forkhead box O1
ENSG00000204060.4 forkhead box O6
ENSG00000176165.7 forkhead box G1
ENSG00000114861.14 forkhead box P1

Activity profile of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Sorted Z-values of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_84630645 8.67 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr7_+_1094921 7.72 ENST00000397095.1
G protein-coupled receptor 146
chr2_+_12857043 5.76 ENST00000381465.2
tribbles pseudokinase 2
chr15_-_70994612 5.76 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr2_+_12857015 5.73 ENST00000155926.4
tribbles pseudokinase 2
chr2_-_165424973 5.60 ENST00000543549.1
growth factor receptor-bound protein 14
chr16_-_30107491 5.34 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
yippee-like 3 (Drosophila)
chr17_+_58755184 5.04 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr1_+_61542922 4.77 ENST00000407417.3
nuclear factor I/A
chr14_-_23288930 4.62 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_-_191878681 4.53 ENST00000409465.1
signal transducer and activator of transcription 1, 91kDa
chr7_+_134832808 4.47 ENST00000275767.3
transmembrane protein 140
chr6_-_42016385 4.47 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
cyclin D3
chr8_-_80993010 4.35 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr5_+_78532003 4.35 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr3_-_168865522 4.26 ENST00000464456.1
MDS1 and EVI1 complex locus
chr14_-_91526922 4.18 ENST00000418736.2
ENST00000261991.3
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr12_+_13349650 4.00 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
epithelial membrane protein 1
chr3_-_18466026 3.98 ENST00000417717.2
SATB homeobox 1
chr3_+_193853927 3.44 ENST00000232424.3
hes family bHLH transcription factor 1
chr18_-_500692 3.43 ENST00000400256.3
collectin sub-family member 12
chr14_+_56585048 3.32 ENST00000267460.4
pellino E3 ubiquitin protein ligase family member 2
chr9_-_94124171 3.29 ENST00000422391.2
ENST00000375731.4
ENST00000303617.5
AU RNA binding protein/enoyl-CoA hydratase
chr2_+_189157498 3.28 ENST00000359135.3
GULP, engulfment adaptor PTB domain containing 1
chr18_-_53070913 3.22 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr9_+_2159850 3.21 ENST00000416751.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_185703513 3.18 ENST00000271588.4
ENST00000367492.2
hemicentin 1
chrX_-_19688475 3.10 ENST00000541422.1
SH3-domain kinase binding protein 1
chr18_-_53257027 3.02 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
transcription factor 4
chr4_-_186696425 3.01 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr9_-_98269481 2.99 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
patched 1
chr12_+_96588279 2.97 ENST00000552142.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr6_+_74405501 2.95 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr1_+_87797351 2.88 ENST00000370542.1
LIM domain only 4
chr8_+_95907993 2.82 ENST00000523378.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr4_-_141075330 2.80 ENST00000509479.2
mastermind-like 3 (Drosophila)
chr18_-_53303123 2.79 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
transcription factor 4
chr2_+_132479948 2.68 ENST00000355171.4
chromosome 2 open reading frame 27A
chr6_+_74405804 2.64 ENST00000287097.5
CD109 molecule
chr11_+_117049910 2.64 ENST00000431081.2
ENST00000524842.1
SID1 transmembrane family, member 2
chr3_-_141868293 2.63 ENST00000317104.7
ENST00000494358.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_33722080 2.59 ENST00000483388.1
ENST00000539719.1
zinc finger protein 362
chr2_+_163175394 2.56 ENST00000446271.1
ENST00000429691.2
grancalcin, EF-hand calcium binding protein
chr1_+_84630367 2.55 ENST00000370680.1
protein kinase, cAMP-dependent, catalytic, beta
chr14_-_74551096 2.50 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr1_+_84630053 2.46 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr2_-_160472952 2.44 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
bromodomain adjacent to zinc finger domain, 2B
chr13_-_67802549 2.41 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr15_-_31283798 2.41 ENST00000435680.1
ENST00000425768.1
myotubularin related protein 10
chr7_+_106809406 2.34 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HMG-box transcription factor 1
chr20_-_45984401 2.34 ENST00000311275.7
zinc finger, MYND-type containing 8
chr2_-_183387430 2.32 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr2_+_189157536 2.28 ENST00000409580.1
ENST00000409637.3
GULP, engulfment adaptor PTB domain containing 1
chr14_+_23067146 2.19 ENST00000428304.2
abhydrolase domain containing 4
chr8_+_11666649 2.19 ENST00000528643.1
ENST00000525777.1
farnesyl-diphosphate farnesyltransferase 1
chr8_-_93107443 2.16 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_124553437 2.13 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr1_-_179112189 2.11 ENST00000512653.1
ENST00000344730.3
c-abl oncogene 2, non-receptor tyrosine kinase
chr21_-_40033618 2.10 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
v-ets avian erythroblastosis virus E26 oncogene homolog
chr5_-_42812143 2.08 ENST00000514985.1
selenoprotein P, plasma, 1
chr15_+_96869165 2.06 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chrX_+_135251783 2.00 ENST00000394153.2
four and a half LIM domains 1
chr6_-_76203345 1.99 ENST00000393004.2
filamin A interacting protein 1
chr21_-_35899113 1.98 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr8_+_70404996 1.95 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr4_-_186733363 1.93 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
sorbin and SH3 domain containing 2
chr2_+_33661382 1.90 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_-_114477787 1.90 ENST00000464560.1
zinc finger and BTB domain containing 20
chr12_-_9268707 1.86 ENST00000318602.7
alpha-2-macroglobulin
chr8_-_8318847 1.86 ENST00000521218.1
CTA-398F10.2
chr9_-_39288092 1.85 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
contactin associated protein-like 3
chr3_-_141868357 1.83 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
transcription factor Dp-2 (E2F dimerization partner 2)
chrX_-_10851762 1.83 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr8_+_52730143 1.80 ENST00000415643.1
Uncharacterized protein
chr1_+_164528866 1.76 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr8_+_95908041 1.73 ENST00000396113.1
ENST00000519136.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr21_+_17443434 1.66 ENST00000400178.2
long intergenic non-protein coding RNA 478
chr6_+_32121789 1.65 ENST00000437001.2
ENST00000375137.2
palmitoyl-protein thioesterase 2
chr11_+_844406 1.65 ENST00000397404.1
tetraspanin 4
chr11_+_117049854 1.61 ENST00000278951.7
SID1 transmembrane family, member 2
chr6_+_32121908 1.61 ENST00000375143.2
ENST00000424499.1
palmitoyl-protein thioesterase 2
chr20_+_306177 1.60 ENST00000544632.1
SRY (sex determining region Y)-box 12
chrX_+_135251835 1.60 ENST00000456445.1
four and a half LIM domains 1
chr14_+_24584508 1.60 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DDB1 and CUL4 associated factor 11
chr12_+_96588143 1.60 ENST00000228741.3
ENST00000547249.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr6_-_76203454 1.59 ENST00000237172.7
filamin A interacting protein 1
chr14_+_24583836 1.58 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11
chr17_+_39394250 1.58 ENST00000254072.6
keratin associated protein 9-8
chr10_-_49482907 1.55 ENST00000374201.3
ENST00000407470.4
FERM and PDZ domain containing 2
chr11_+_117049445 1.53 ENST00000324225.4
ENST00000532960.1
SID1 transmembrane family, member 2
chr6_+_72922590 1.52 ENST00000523963.1
regulating synaptic membrane exocytosis 1
chr15_-_52944231 1.50 ENST00000546305.2
family with sequence similarity 214, member A
chr4_-_152149033 1.49 ENST00000514152.1
SH3 domain containing 19
chr6_+_72922505 1.48 ENST00000401910.3
regulating synaptic membrane exocytosis 1
chr19_+_12902289 1.47 ENST00000302754.4
jun B proto-oncogene
chr12_-_92539614 1.45 ENST00000256015.3
B-cell translocation gene 1, anti-proliferative
chr6_+_139094657 1.44 ENST00000332797.6
coiled-coil domain containing 28A
chr11_+_844067 1.44 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
tetraspanin 4
chr2_-_157189180 1.44 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
nuclear receptor subfamily 4, group A, member 2
chr8_-_28243934 1.44 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
zinc finger protein 395
chr7_-_27213893 1.40 ENST00000283921.4
homeobox A10
chr7_-_37026108 1.40 ENST00000396045.3
engulfment and cell motility 1
chr21_+_17443521 1.39 ENST00000456342.1
long intergenic non-protein coding RNA 478
chr7_+_91570165 1.35 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
A kinase (PRKA) anchor protein 9
chr20_+_62887081 1.34 ENST00000369758.4
ENST00000299468.7
ENST00000609372.1
ENST00000610196.1
ENST00000308824.6
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr2_-_26205340 1.33 ENST00000264712.3
kinesin family member 3C
chr2_-_183387064 1.27 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
phosphodiesterase 1A, calmodulin-dependent
chr7_+_77469439 1.26 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr3_-_114477962 1.26 ENST00000471418.1
zinc finger and BTB domain containing 20
chrX_+_135252050 1.25 ENST00000449474.1
ENST00000345434.3
four and a half LIM domains 1
chr1_+_84609944 1.24 ENST00000370685.3
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_198126093 1.23 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NIMA-related kinase 7
chr18_-_53177984 1.22 ENST00000543082.1
transcription factor 4
chr3_-_93692781 1.21 ENST00000394236.3
protein S (alpha)
chr9_-_107690420 1.20 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr1_+_161136180 1.20 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
protoporphyrinogen oxidase
chr21_+_17792672 1.17 ENST00000602620.1
long intergenic non-protein coding RNA 478
chr9_-_98279241 1.16 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
patched 1
chr17_-_8059638 1.16 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
period circadian clock 1
chr7_-_105332084 1.16 ENST00000472195.1
ataxin 7-like 1
chr1_-_94079648 1.15 ENST00000370247.3
breast cancer anti-estrogen resistance 3
chr3_+_113616317 1.12 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr2_-_157198860 1.12 ENST00000409572.1
nuclear receptor subfamily 4, group A, member 2
chr1_+_65730385 1.12 ENST00000263441.7
ENST00000395325.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_-_179112173 1.11 ENST00000408940.3
ENST00000504405.1
c-abl oncogene 2, non-receptor tyrosine kinase
chr20_+_306221 1.11 ENST00000342665.2
SRY (sex determining region Y)-box 12
chr18_-_22932080 1.11 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
zinc finger protein 521
chr20_+_10199468 1.10 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr5_-_42811986 1.10 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr10_+_30722866 1.09 ENST00000263056.1
mitogen-activated protein kinase kinase kinase 8
chr2_+_177053307 1.08 ENST00000331462.4
homeobox D1
chr6_+_89791507 1.07 ENST00000354922.3
proline-rich nuclear receptor coactivator 1
chr6_-_159466042 1.06 ENST00000338313.5
T-cell activation RhoGTPase activating protein
chr8_-_127570603 1.06 ENST00000304916.3
family with sequence similarity 84, member B
chr4_-_111119804 1.06 ENST00000394607.3
ENST00000302274.3
ELOVL fatty acid elongase 6
chr1_+_227127981 1.05 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
aarF domain containing kinase 3
chr9_-_84303269 1.04 ENST00000418319.1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr11_+_46402297 1.02 ENST00000405308.2
midkine (neurite growth-promoting factor 2)
chr6_+_136172820 1.02 ENST00000308191.6
phosphodiesterase 7B
chr8_-_71316021 1.01 ENST00000452400.2
nuclear receptor coactivator 2
chr7_-_17980091 1.01 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
sorting nexin 13
chr3_+_159570722 1.00 ENST00000482804.1
schwannomin interacting protein 1
chr2_+_86947296 1.00 ENST00000283632.4
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_-_68547061 0.98 ENST00000263655.3
cannabinoid receptor interacting protein 1
chr8_-_29208183 0.98 ENST00000240100.2
dual specificity phosphatase 4
chr10_+_111985713 0.98 ENST00000239007.7
MAX interactor 1, dimerization protein
chr10_+_23728198 0.98 ENST00000376495.3
OTU domain containing 1
chr7_-_27219849 0.98 ENST00000396344.4
homeobox A10
chr5_+_72251793 0.97 ENST00000430046.2
ENST00000341845.6
FCH domain only 2
chrX_-_117119243 0.97 ENST00000539496.1
ENST00000469946.1
kelch-like family member 13
chr1_+_120839412 0.95 ENST00000355228.4
family with sequence similarity 72, member B
chr8_-_93107696 0.94 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_-_71031185 0.94 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
protein tyrosine phosphatase, receptor type, B
chr14_-_74551172 0.93 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr12_-_71551868 0.93 ENST00000247829.3
tetraspanin 8
chr2_+_173686303 0.92 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chrX_-_106960285 0.92 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr1_+_203651937 0.91 ENST00000341360.2
ATPase, Ca++ transporting, plasma membrane 4
chr1_+_162602244 0.91 ENST00000367922.3
ENST00000367921.3
discoidin domain receptor tyrosine kinase 2
chr16_-_4665023 0.90 ENST00000591897.1
UBA-like domain containing 1
chr4_-_147043058 0.86 ENST00000512063.1
ENST00000507726.1
long intergenic non-protein coding RNA 1095
chr3_-_3221358 0.86 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
cereblon
chr12_-_71031220 0.86 ENST00000334414.6
protein tyrosine phosphatase, receptor type, B
chr2_-_160473114 0.86 ENST00000392783.2
bromodomain adjacent to zinc finger domain, 2B
chr16_-_4664860 0.86 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBA-like domain containing 1
chr19_-_39826639 0.85 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
glia maturation factor, gamma
chr16_-_86542652 0.85 ENST00000599749.1
FOXF1 adjacent non-coding developmental regulatory RNA
chr3_+_50192537 0.83 ENST00000002829.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_+_26150628 0.82 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr14_-_36989336 0.82 ENST00000522719.2
NK2 homeobox 1
chr3_+_50192499 0.82 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_-_93107827 0.80 ENST00000520724.1
ENST00000518844.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_109223595 0.79 ENST00000410093.1
LIM and senescent cell antigen-like domains 1
chr17_-_7082861 0.79 ENST00000269299.3
asialoglycoprotein receptor 1
chr7_-_140178775 0.79 ENST00000474576.1
ENST00000473444.1
ENST00000471104.1
makorin ring finger protein 1
chr12_-_71551652 0.78 ENST00000546561.1
tetraspanin 8
chr14_+_50234827 0.78 ENST00000554589.1
ENST00000557247.1
kelch domain containing 2
chr4_+_87928140 0.76 ENST00000307808.6
AF4/FMR2 family, member 1
chr10_+_99079008 0.76 ENST00000371021.3
frequently rearranged in advanced T-cell lymphomas
chr6_-_32191834 0.75 ENST00000375023.3
notch 4
chr1_-_8585945 0.75 ENST00000377464.1
arginine-glutamic acid dipeptide (RE) repeats
chrX_-_63005405 0.74 ENST00000374878.1
ENST00000437457.2
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr11_+_46402482 0.74 ENST00000441869.1
midkine (neurite growth-promoting factor 2)
chr17_-_8263538 0.74 ENST00000535173.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr2_+_33701286 0.74 ENST00000403687.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr22_-_31688381 0.73 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr21_+_17442799 0.73 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
long intergenic non-protein coding RNA 478
chr17_+_58677539 0.73 ENST00000305921.3
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr10_+_97515409 0.73 ENST00000371207.3
ENST00000543964.1
ectonucleoside triphosphate diphosphohydrolase 1
chr13_-_41240717 0.72 ENST00000379561.5
forkhead box O1
chr18_+_56530136 0.72 ENST00000591083.1
zinc finger protein 532
chr17_+_65374075 0.71 ENST00000581322.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr14_+_58894103 0.71 ENST00000354386.6
ENST00000556134.1
KIAA0586
chr1_-_168106536 0.70 ENST00000537209.1
ENST00000361697.2
ENST00000546300.1
ENST00000367835.1
G protein-coupled receptor 161
chr5_+_140602904 0.70 ENST00000515856.2
ENST00000239449.4
protocadherin beta 14
chr2_+_65283529 0.69 ENST00000546106.1
ENST00000537589.1
ENST00000260569.4
centrosomal protein 68kDa
chr2_+_65283506 0.69 ENST00000377990.2
centrosomal protein 68kDa
chr15_+_57511609 0.69 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
transcription factor 12
chr3_+_178866199 0.68 ENST00000263967.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr10_+_119301928 0.66 ENST00000553456.3
empty spiracles homeobox 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.5 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
2.1 14.9 GO:0097338 response to clozapine(GO:0097338)
1.2 3.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.1 4.5 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.9 5.6 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.9 5.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.9 4.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.9 3.4 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.9 2.6 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.8 4.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.7 2.9 GO:0010157 response to chlorate(GO:0010157)
0.7 3.4 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.6 3.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.5 2.1 GO:0009956 radial pattern formation(GO:0009956)
0.5 2.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.5 5.8 GO:0033227 dsRNA transport(GO:0033227)
0.4 2.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.4 3.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.4 2.3 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.4 1.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.4 3.3 GO:0006552 leucine catabolic process(GO:0006552)
0.3 2.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.3 3.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.3 1.0 GO:0036071 N-glycan fucosylation(GO:0036071)
0.3 0.3 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.3 1.2 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.3 1.8 GO:0030421 defecation(GO:0030421)
0.3 5.3 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.3 5.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 4.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 0.7 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 1.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 4.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.2 0.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 1.6 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 2.9 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.2 1.0 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.2 1.4 GO:0070417 cellular response to cold(GO:0070417)
0.2 0.6 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2 2.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 1.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.7 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 4.8 GO:0072189 ureter development(GO:0072189)
0.2 0.5 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.2 0.5 GO:0001079 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 0.5 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2 3.0 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 0.5 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 2.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.4 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 0.4 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.6 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.1 0.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.6 GO:0019087 transformation of host cell by virus(GO:0019087)
0.1 2.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0018032 protein amidation(GO:0018032)
0.1 0.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.6 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 4.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 1.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 1.6 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 4.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 1.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 1.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 1.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 5.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 1.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 4.0 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.1 1.0 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 1.0 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.5 GO:0071603 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.1 4.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 3.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.7 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 1.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.0 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.5 GO:0009597 detection of virus(GO:0009597)
0.1 0.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 1.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.3 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 2.9 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.1 3.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.4 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.6 GO:0044211 CTP salvage(GO:0044211)
0.1 6.8 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 0.9 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 8.9 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 3.9 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 1.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.1 0.3 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.2 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286) DNA dephosphorylation(GO:0098502)
0.1 1.2 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.4 GO:0001692 histamine metabolic process(GO:0001692)
0.1 1.1 GO:0006768 biotin metabolic process(GO:0006768)
0.1 2.2 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 0.5 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 5.8 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 2.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.2 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
0.1 1.0 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 1.3 GO:2000811 negative regulation of anoikis(GO:2000811)
0.1 0.2 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 3.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.4 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 13.0 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 1.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0009624 response to nematode(GO:0009624)
0.0 0.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.3 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0030820 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.0 0.7 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 1.0 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.3 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.0 0.4 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.4 GO:0010324 membrane invagination(GO:0010324)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 1.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.5 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.4 GO:0002091 negative regulation of receptor internalization(GO:0002091) stress granule assembly(GO:0034063)
0.0 0.5 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.8 GO:0016577 histone demethylation(GO:0016577)
0.0 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.5 GO:0002076 osteoblast development(GO:0002076)
0.0 0.2 GO:0070649 cleavage furrow formation(GO:0036089) polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 1.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 3.3 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.3 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0010159 specification of organ position(GO:0010159)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 1.3 GO:0072384 organelle transport along microtubule(GO:0072384)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.0 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 1.6 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.0 GO:0003160 endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 15.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 2.9 GO:0044294 dendritic growth cone(GO:0044294)
0.3 1.0 GO:0034657 GID complex(GO:0034657)
0.3 2.0 GO:0035976 AP1 complex(GO:0035976)
0.2 4.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 6.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 5.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 3.3 GO:0071564 npBAF complex(GO:0071564)
0.1 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 4.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 4.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 10.7 GO:0032993 protein-DNA complex(GO:0032993)
0.1 2.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 2.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.1 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 4.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 3.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 3.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 1.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 8.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 3.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0044218 growing cell tip(GO:0035838) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 1.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0035859 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.0 1.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 9.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.5 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 2.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 9.7 GO:0005925 focal adhesion(GO:0005925)
0.0 5.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.0 GO:0005795 Golgi stack(GO:0005795)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 3.1 GO:0010008 endosome membrane(GO:0010008)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 3.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
1.5 4.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.0 5.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.9 11.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.8 14.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.6 1.9 GO:0019959 interleukin-8 binding(GO:0019959)
0.6 4.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.5 2.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.5 9.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.5 2.9 GO:0005119 smoothened binding(GO:0005119)
0.5 5.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 3.4 GO:0005534 galactose binding(GO:0005534)
0.4 1.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 2.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 2.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 3.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 1.0 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.3 1.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 4.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.3 0.9 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 1.1 GO:0047708 biotinidase activity(GO:0047708)
0.3 3.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.3 1.0 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.2 0.7 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.2 1.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 5.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 1.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 3.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 0.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.5 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 1.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 5.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.5 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 3.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.6 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 2.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 2.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.6 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 1.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 4.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 4.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.6 GO:0038191 neuropilin binding(GO:0038191)
0.1 4.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 3.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 3.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.5 GO:0043559 insulin binding(GO:0043559)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.8 GO:0048156 tau protein binding(GO:0048156)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 2.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.6 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 2.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 6.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 3.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 1.1 GO:0030552 cAMP binding(GO:0030552)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 4.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 3.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0005167 neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
0.0 2.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 2.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 4.3 GO:0044325 ion channel binding(GO:0044325)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 3.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 4.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.6 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 5.3 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.8 PID IL3 PATHWAY IL3-mediated signaling events
0.3 3.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 3.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 7.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 14.1 PID E2F PATHWAY E2F transcription factor network
0.1 3.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 7.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 3.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 6.3 PID INSULIN PATHWAY Insulin Pathway
0.1 6.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 8.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 4.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 3.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 3.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 4.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 3.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity