Project
Inflammatory response time course, HUVEC (Wada et al., 2009)
Navigation
Downloads
Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
Z-value: 1.06
Motif logo
Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSG00000251493.2 | forkhead box D1 | |
| ENSG00000150907.6 | forkhead box O1 | |
| ENSG00000204060.4 | forkhead box O6 | |
| ENSG00000176165.7 | forkhead box G1 | |
| ENSG00000114861.14 | forkhead box P1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXG1 | hg19_v2_chr14_+_29236269_29236287, hg19_v2_chr14_+_29234870_29235050 | -0.49 | 1.3e-02 | Click! |
| FOXP1 | hg19_v2_chr3_-_71179988_71180085, hg19_v2_chr3_-_71179699_71179744 | -0.45 | 2.3e-02 | Click! |
| FOXO6 | hg19_v2_chr1_+_41827594_41827594 | 0.42 | 3.7e-02 | Click! |
| FOXO1 | hg19_v2_chr13_-_41240717_41240735 | 0.41 | 3.9e-02 | Click! |
| FOXD1 | hg19_v2_chr5_-_72744336_72744359 | -0.19 | 3.6e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 14.9 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.0 | 13.0 | GO:0065004 | protein-DNA complex assembly(GO:0065004) |
| 2.3 | 11.5 | GO:0045074 | interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) |
| 0.1 | 8.9 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.1 | 6.8 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.5 | 5.8 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.1 | 5.8 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.3 | 5.7 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.9 | 5.6 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.1 | 5.6 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 15.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 10.7 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 9.7 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 9.2 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 8.0 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.2 | 6.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 5.7 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.2 | 5.0 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 4.6 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 4.5 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 14.9 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.9 | 11.1 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.5 | 9.2 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.0 | 6.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 1.0 | 5.8 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.2 | 5.4 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 5.3 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 5.3 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.5 | 5.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 1.7 | 5.0 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 15.8 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.1 | 14.1 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 8.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 7.3 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.1 | 7.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 6.3 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.1 | 6.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 4.3 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 4.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 3.8 | PID ARF6 PATHWAY | Arf6 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 14.9 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.2 | 12.2 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.3 | 7.2 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.2 | 7.0 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 6.4 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 5.4 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.2 | 5.2 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 4.6 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 4.4 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.2 | 4.1 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |