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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FOXJ2

Z-value: 0.81

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Transcription factors associated with FOXJ2

Gene Symbol Gene ID Gene Info
FOXJ2
ENSG00000065970.4 forkhead box J2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXJ2hg19_v2_chr12_+_8185288_8185339-0.376.6e-02Click!

Activity profile of FOXJ2 motif

Sorted Z-values of FOXJ2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_67430339 4.78 ENST00000439724.3
SMAD3
SMAD family member 3
chr8_+_104383728 2.19 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr2_+_162016827 2.02 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr11_+_35201826 1.74 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr1_+_165797024 1.71 ENST00000372212.4
UCK2
uridine-cytidine kinase 2
chr9_+_5510492 1.59 ENST00000397745.2
PDCD1LG2
programmed cell death 1 ligand 2
chr9_+_5510558 1.55 ENST00000397747.3
PDCD1LG2
programmed cell death 1 ligand 2
chr2_+_162016804 1.41 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr21_-_35899113 1.41 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr9_-_134615443 1.13 ENST00000372195.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr7_-_115608304 1.11 ENST00000457268.1
TFEC
transcription factor EC
chr2_+_162016916 1.10 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr17_+_25958174 1.07 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr7_-_80548667 1.04 ENST00000265361.3
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_+_28822417 0.81 ENST00000428935.1
ENST00000420266.1
WAC
WW domain containing adaptor with coiled-coil
chr21_-_27423339 0.81 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr1_-_43855444 0.77 ENST00000372455.4
MED8
mediator complex subunit 8
chr10_+_28822636 0.75 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr10_-_36813162 0.74 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr11_-_57089671 0.71 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chrX_+_108780347 0.70 ENST00000372103.1
NXT2
nuclear transport factor 2-like export factor 2
chr19_+_7030589 0.69 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr10_+_33271469 0.67 ENST00000414157.1
RP11-462L8.1
RP11-462L8.1
chr6_+_30539153 0.66 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ABCF1
ATP-binding cassette, sub-family F (GCN20), member 1
chr1_+_150122034 0.66 ENST00000025469.6
ENST00000369124.4
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr10_+_118305435 0.65 ENST00000369221.2
PNLIP
pancreatic lipase
chr2_-_239140011 0.61 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
AC016757.3
Protein LOC151174
chr19_-_55677920 0.60 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr3_+_171757346 0.59 ENST00000421757.1
ENST00000415807.2
ENST00000392699.1
FNDC3B
fibronectin type III domain containing 3B
chr12_+_54891495 0.59 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr2_-_239140276 0.57 ENST00000334973.4
AC016757.3
Protein LOC151174
chr15_+_66797627 0.57 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chrX_-_6453159 0.56 ENST00000381089.3
ENST00000398729.1
VCX3A
variable charge, X-linked 3A
chr3_-_190167571 0.52 ENST00000354905.2
TMEM207
transmembrane protein 207
chr6_+_11094266 0.52 ENST00000416247.2
SMIM13
small integral membrane protein 13
chr19_-_7058651 0.52 ENST00000333843.4
MBD3L3
methyl-CpG binding domain protein 3-like 3
chr17_-_39324424 0.52 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr12_-_10251539 0.51 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr20_-_42355629 0.50 ENST00000373003.1
GTSF1L
gametocyte specific factor 1-like
chr7_-_102283238 0.50 ENST00000340457.8
UPK3BL
uroplakin 3B-like
chr1_-_72566613 0.50 ENST00000306821.3
NEGR1
neuronal growth regulator 1
chr4_-_47983519 0.49 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr21_-_37451680 0.49 ENST00000399201.1
SETD4
SET domain containing 4
chr19_-_7040190 0.48 ENST00000381394.4
MBD3L4
methyl-CpG binding domain protein 3-like 4
chr7_+_23637763 0.48 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr2_+_120770645 0.48 ENST00000443902.2
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr4_+_89299885 0.48 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr8_+_38585704 0.47 ENST00000519416.1
ENST00000520615.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr15_+_74165945 0.45 ENST00000535547.2
ENST00000300504.2
ENST00000562056.1
TBC1D21
TBC1 domain family, member 21
chrX_+_7810303 0.45 ENST00000381059.3
ENST00000341408.4
VCX
variable charge, X-linked
chr2_+_101591314 0.44 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr12_-_53074182 0.44 ENST00000252244.3
KRT1
keratin 1
chr4_+_89299994 0.43 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr1_+_43855560 0.43 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chrX_+_108779004 0.42 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr8_+_101170257 0.42 ENST00000251809.3
SPAG1
sperm associated antigen 1
chr12_-_10251603 0.42 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr19_+_11658655 0.42 ENST00000588935.1
CNN1
calponin 1, basic, smooth muscle
chr1_+_160765884 0.41 ENST00000392203.4
LY9
lymphocyte antigen 9
chr19_+_56989609 0.41 ENST00000601875.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr1_+_160765860 0.40 ENST00000368037.5
LY9
lymphocyte antigen 9
chr1_-_85100703 0.40 ENST00000370624.1
C1orf180
chromosome 1 open reading frame 180
chr1_+_45212074 0.39 ENST00000372217.1
KIF2C
kinesin family member 2C
chr3_-_150690471 0.39 ENST00000468836.1
ENST00000328863.4
CLRN1
clarin 1
chr4_+_68424434 0.39 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr12_-_10251576 0.39 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr15_+_66797455 0.39 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr1_+_160765919 0.38 ENST00000341032.4
ENST00000368041.2
ENST00000368040.1
LY9
lymphocyte antigen 9
chr9_-_130679257 0.37 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr3_+_157154578 0.37 ENST00000295927.3
PTX3
pentraxin 3, long
chr7_+_108210012 0.36 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr3_+_128444994 0.35 ENST00000482525.1
RAB7A
RAB7A, member RAS oncogene family
chr2_+_210517895 0.34 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr17_-_56494713 0.33 ENST00000407977.2
RNF43
ring finger protein 43
chr14_+_88471468 0.33 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr8_-_33424636 0.33 ENST00000256257.1
RNF122
ring finger protein 122
chr9_-_99417562 0.33 ENST00000375234.3
ENST00000446045.1
AAED1
AhpC/TSA antioxidant enzyme domain containing 1
chr8_+_30244580 0.32 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr11_+_6226782 0.32 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42
chr17_-_56494882 0.32 ENST00000584437.1
RNF43
ring finger protein 43
chr4_-_140544386 0.31 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr6_+_31462658 0.31 ENST00000538442.1
MICB
MHC class I polypeptide-related sequence B
chr18_+_32455201 0.31 ENST00000590831.2
DTNA
dystrobrevin, alpha
chr1_-_43855479 0.31 ENST00000290663.6
ENST00000372457.4
MED8
mediator complex subunit 8
chr16_-_30440530 0.31 ENST00000568434.1
DCTPP1
dCTP pyrophosphatase 1
chr1_-_27952741 0.31 ENST00000399173.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr17_-_27054952 0.31 ENST00000580518.1
TLCD1
TLC domain containing 1
chr15_-_55881135 0.30 ENST00000302000.6
PYGO1
pygopus family PHD finger 1
chrX_-_30877837 0.29 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr7_-_33140498 0.27 ENST00000448915.1
RP9
retinitis pigmentosa 9 (autosomal dominant)
chr12_-_92536433 0.27 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr12_+_108523133 0.27 ENST00000547525.1
WSCD2
WSC domain containing 2
chr10_-_111713633 0.27 ENST00000538668.1
ENST00000369657.1
ENST00000369655.1
RP11-451M19.3
Uncharacterized protein
chr17_-_56494908 0.26 ENST00000577716.1
RNF43
ring finger protein 43
chr3_-_57233966 0.26 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr4_-_68749745 0.26 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr2_-_85641162 0.26 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG
capping protein (actin filament), gelsolin-like
chr17_+_66511540 0.25 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr7_+_99425633 0.25 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
CYP3A43
cytochrome P450, family 3, subfamily A, polypeptide 43
chr4_-_68749699 0.24 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr9_+_5890802 0.24 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
MLANA
melan-A
chr9_+_108424738 0.24 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr2_+_120770686 0.23 ENST00000331393.4
ENST00000443124.1
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr11_+_63137251 0.23 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr1_+_222988464 0.23 ENST00000420335.1
RP11-452F19.3
RP11-452F19.3
chr6_-_26124138 0.23 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chrX_+_102024075 0.23 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
LINC00630
long intergenic non-protein coding RNA 630
chr14_+_52456327 0.22 ENST00000556760.1
C14orf166
chromosome 14 open reading frame 166
chr17_+_17685422 0.22 ENST00000395774.1
RAI1
retinoic acid induced 1
chr1_+_239882842 0.22 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr5_-_110062384 0.22 ENST00000429839.2
TMEM232
transmembrane protein 232
chr3_+_128444965 0.22 ENST00000265062.3
RAB7A
RAB7A, member RAS oncogene family
chr10_+_105005644 0.22 ENST00000441178.2
RP11-332O19.5
ribulose-5-phosphate-3-epimerase-like 1
chr3_+_63428752 0.22 ENST00000295894.5
SYNPR
synaptoporin
chr13_+_30510003 0.22 ENST00000400540.1
LINC00544
long intergenic non-protein coding RNA 544
chr1_+_36335351 0.22 ENST00000373206.1
AGO1
argonaute RISC catalytic component 1
chr5_-_110062349 0.21 ENST00000511883.2
ENST00000455884.2
TMEM232
transmembrane protein 232
chr18_+_44812072 0.21 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1
CTD-2130O13.1
chr10_+_60936347 0.21 ENST00000373880.4
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr6_-_130543958 0.20 ENST00000437477.2
ENST00000439090.2
SAMD3
sterile alpha motif domain containing 3
chr4_-_123542224 0.19 ENST00000264497.3
IL21
interleukin 21
chr12_+_123949053 0.19 ENST00000350887.5
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr19_+_49866331 0.19 ENST00000597873.1
DKKL1
dickkopf-like 1
chr11_-_5537920 0.19 ENST00000380184.1
UBQLNL
ubiquilin-like
chr2_+_132160448 0.19 ENST00000437751.1
AC073869.19
long intergenic non-protein coding RNA 1120
chr19_+_54619125 0.18 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
PRPF31
pre-mRNA processing factor 31
chr3_+_57875711 0.18 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr1_+_117963209 0.17 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr1_-_27701307 0.17 ENST00000270879.4
ENST00000354982.2
FCN3
ficolin (collagen/fibrinogen domain containing) 3
chr16_+_5121814 0.17 ENST00000262374.5
ENST00000586840.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr1_+_248402231 0.17 ENST00000306687.1
OR2M4
olfactory receptor, family 2, subfamily M, member 4
chr6_-_10747802 0.17 ENST00000606522.1
ENST00000606652.1
RP11-421M1.8
RP11-421M1.8
chr1_+_146373546 0.17 ENST00000446760.2
NBPF12
neuroblastoma breakpoint family, member 12
chr12_-_102874378 0.17 ENST00000456098.1
IGF1
insulin-like growth factor 1 (somatomedin C)
chr19_+_56989485 0.16 ENST00000585445.1
ENST00000586091.1
ENST00000594783.1
ENST00000592146.1
ENST00000588158.1
ENST00000299997.4
ENST00000591797.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr9_-_26892765 0.16 ENST00000520187.1
ENST00000333916.5
CAAP1
caspase activity and apoptosis inhibitor 1
chr5_-_34919094 0.16 ENST00000341754.4
RAD1
RAD1 homolog (S. pombe)
chr3_+_132036207 0.15 ENST00000336375.5
ENST00000495911.1
ACPP
acid phosphatase, prostate
chr15_-_34628951 0.15 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr20_+_36373032 0.15 ENST00000373473.1
CTNNBL1
catenin, beta like 1
chr4_-_38806404 0.15 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1
toll-like receptor 1
chr14_+_52456193 0.15 ENST00000261700.3
C14orf166
chromosome 14 open reading frame 166
chr11_-_125550764 0.14 ENST00000527795.1
ACRV1
acrosomal vesicle protein 1
chr13_-_38172863 0.14 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr2_-_206950781 0.14 ENST00000403263.1
INO80D
INO80 complex subunit D
chr12_-_7596735 0.14 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr11_-_57417405 0.14 ENST00000524669.1
ENST00000300022.3
YPEL4
yippee-like 4 (Drosophila)
chr7_+_132937820 0.14 ENST00000393161.2
ENST00000253861.4
EXOC4
exocyst complex component 4
chr6_+_33422343 0.14 ENST00000395064.2
ZBTB9
zinc finger and BTB domain containing 9
chr10_-_105992059 0.14 ENST00000369720.1
ENST00000369719.1
ENST00000357060.3
ENST00000428666.1
ENST00000278064.2
WDR96
WD repeat domain 96
chr9_-_136006496 0.14 ENST00000372062.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr12_-_8815215 0.14 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr12_-_102874416 0.13 ENST00000392904.1
ENST00000337514.6
IGF1
insulin-like growth factor 1 (somatomedin C)
chr3_+_122103014 0.13 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
FAM162A
family with sequence similarity 162, member A
chr3_-_49131788 0.13 ENST00000395443.2
ENST00000411682.1
QRICH1
glutamine-rich 1
chr2_+_90121477 0.13 ENST00000483379.1
IGKV1D-17
immunoglobulin kappa variable 1D-17
chr6_-_52628271 0.13 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr11_+_118398178 0.13 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr15_+_64428529 0.12 ENST00000560861.1
SNX1
sorting nexin 1
chr14_+_90863327 0.12 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr1_+_162039558 0.11 ENST00000530878.1
ENST00000361897.5
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr13_+_43355732 0.11 ENST00000313851.1
FAM216B
family with sequence similarity 216, member B
chr6_+_31082603 0.11 ENST00000259881.9
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr1_-_19811132 0.11 ENST00000433834.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr1_-_230513367 0.11 ENST00000321327.2
ENST00000525115.1
PGBD5
piggyBac transposable element derived 5
chr12_+_21679220 0.10 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr16_+_72459838 0.10 ENST00000564508.1
AC004158.3
AC004158.3
chr3_+_57875738 0.10 ENST00000417128.1
ENST00000438794.1
SLMAP
sarcolemma associated protein
chr9_+_133569108 0.10 ENST00000372358.5
ENST00000546165.1
ENST00000372352.3
ENST00000372351.3
ENST00000372350.3
ENST00000495699.2
EXOSC2
exosome component 2
chr3_+_52017454 0.10 ENST00000476854.1
ENST00000476351.1
ENST00000494103.1
ENST00000404366.2
ENST00000469863.1
ACY1
aminoacylase 1
chr17_-_79838860 0.09 ENST00000582866.1
RP11-498C9.15
RP11-498C9.15
chr12_-_8815299 0.09 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr14_+_37126765 0.09 ENST00000402703.2
PAX9
paired box 9
chr12_+_27863706 0.09 ENST00000081029.3
ENST00000538315.1
ENST00000542791.1
MRPS35
mitochondrial ribosomal protein S35
chr7_+_72742178 0.09 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr16_+_3068393 0.09 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chrX_+_22056165 0.08 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr22_-_39268308 0.08 ENST00000407418.3
CBX6
chromobox homolog 6
chr3_+_178866199 0.08 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr6_-_167571817 0.08 ENST00000366834.1
GPR31
G protein-coupled receptor 31
chr20_+_55926583 0.08 ENST00000395840.2
RAE1
ribonucleic acid export 1
chr8_+_85095769 0.07 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr10_+_50887683 0.07 ENST00000374113.3
ENST00000374111.3
ENST00000374112.3
ENST00000535836.1
C10orf53
chromosome 10 open reading frame 53
chr12_-_57941004 0.07 ENST00000550750.1
ENST00000548249.1
DCTN2
dynactin 2 (p50)
chr3_-_109056419 0.07 ENST00000335658.6
DPPA4
developmental pluripotency associated 4
chr12_+_6833237 0.07 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COPS7A
COP9 signalosome subunit 7A
chr1_+_32739733 0.07 ENST00000333070.4
LCK
lymphocyte-specific protein tyrosine kinase
chr14_+_38264418 0.06 ENST00000267368.7
ENST00000382320.3
TTC6
tetratricopeptide repeat domain 6
chr17_-_64225508 0.06 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr3_-_64009658 0.06 ENST00000394431.2
PSMD6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr1_-_38019878 0.06 ENST00000296215.6
SNIP1
Smad nuclear interacting protein 1
chr4_-_159956333 0.06 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr1_+_73771844 0.06 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
RP4-598G3.1
chr6_+_10747986 0.06 ENST00000379542.5
TMEM14B
transmembrane protein 14B
chr18_+_3447572 0.05 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chr2_-_74619152 0.05 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chr10_+_28822236 0.05 ENST00000347934.4
ENST00000354911.4
WAC
WW domain containing adaptor with coiled-coil
chr4_+_57845024 0.05 ENST00000431623.2
ENST00000441246.2
POLR2B
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr17_+_73629500 0.05 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr7_-_144435985 0.05 ENST00000549981.1
TPK1
thiamin pyrophosphokinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.8 4.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4 1.7 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.4 1.6 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.4 1.1 GO:2001190 natural killer cell tolerance induction(GO:0002519) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.3 2.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 1.7 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 1.0 GO:0003350 pulmonary myocardium development(GO:0003350)
0.2 3.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 0.6 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.2 0.9 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.8 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.6 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.4 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 1.1 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.3 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 1.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 1.4 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.1 0.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.3 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 0.4 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.2 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.1 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.7 GO:0051451 myoblast migration(GO:0051451)
0.0 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:1903947 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.7 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 1.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 1.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) regulation of genetic imprinting(GO:2000653)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.4 GO:0051775 response to redox state(GO:0051775)
0.0 0.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.7 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.4 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0007289 spermatid nucleus differentiation(GO:0007289)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 1.0 GO:1990423 RZZ complex(GO:1990423)
0.2 0.7 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.8 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.8 4.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 1.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.1 GO:0048030 disaccharide binding(GO:0048030)
0.2 1.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.8 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 3.1 GO:0005109 frizzled binding(GO:0005109)
0.1 2.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 4.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 3.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 1.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis