ISMARA results: FOXL1

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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FOXL1

Z-value: 1.71

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Transcription factors associated with FOXL1

Gene Symbol	Gene ID	Gene Info
FOXL1 Ensembl NCBI GeneCards UniProt	ENSG00000176678.4	forkhead box L1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXL1	hg19_v2_chr16_+_86612112_86612123	-0.10	6.2e-01	Click!

Activity profile of FOXL1 motif

Sorted Z-values of FOXL1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_+_8543393 Show fit	32.36	ENST00000157600.3 ENST00000415597.1 ENST00000535732.1	LMCD1 Ensembl NCBI GeneCards UniProt Show fit	LIM and cysteine-rich domains 1
chr3_+_8543533 Show fit	21.96	ENST00000454244.1	LMCD1 Ensembl NCBI GeneCards UniProt Show fit	LIM and cysteine-rich domains 1
chr3_+_8543561 Show fit	20.35	ENST00000397386.3	LMCD1 Ensembl NCBI GeneCards UniProt Show fit	LIM and cysteine-rich domains 1
chr4_+_41540160 Show fit	10.72	ENST00000503057.1 ENST00000511496.1	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr5_-_43043272 Show fit	7.45	ENST00000314890.3	ANXA2R Ensembl NCBI GeneCards UniProt Show fit	annexin A2 receptor
chr9_-_47314222 Show fit	7.32	ENST00000420228.1 ENST00000438517.1 ENST00000414020.1	AL953854.2 Ensembl NCBI GeneCards UniProt Show fit	AL953854.2
chr1_+_84630645 Show fit	6.95	ENST00000394839.2	PRKACB Ensembl NCBI GeneCards UniProt Show fit	protein kinase, cAMP-dependent, catalytic, beta
chr4_-_186877806 Show fit	6.77	ENST00000355634.5	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr6_+_116832789 Show fit	5.30	ENST00000368599.3	FAM26E Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 26, member E
chr11_+_71238313 Show fit	4.91	ENST00000398536.4	KRTAP5-7 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 5-7
chr1_-_76076793 Show fit	4.54	ENST00000370859.3	SLC44A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 44, member 5
chr9_-_74675521 Show fit	4.54	ENST00000377024.3	C9orf57 Ensembl NCBI GeneCards UniProt Show fit	chromosome 9 open reading frame 57
chr9_-_14180778 Show fit	4.41	ENST00000380924.1 ENST00000543693.1	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I/B
chr1_+_84630053 Show fit	4.28	ENST00000394838.2 ENST00000370682.3 ENST00000432111.1	PRKACB Ensembl NCBI GeneCards UniProt Show fit	protein kinase, cAMP-dependent, catalytic, beta
chr3_+_193853927 Show fit	4.19	ENST00000232424.3	HES1 Ensembl NCBI GeneCards UniProt Show fit	hes family bHLH transcription factor 1
chr2_-_165424973 Show fit	3.83	ENST00000543549.1	GRB14 Ensembl NCBI GeneCards UniProt Show fit	growth factor receptor-bound protein 14
chrX_-_117119243 Show fit	3.81	ENST00000539496.1 ENST00000469946.1	KLHL13 Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 13
chr17_+_61086917 Show fit	3.72	ENST00000424789.2 ENST00000389520.4	TANC2 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr19_-_38916802 Show fit	3.70	ENST00000587738.1	RASGRP4 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 4
chr1_+_61547894 Show fit	3.60	ENST00000403491.3	NFIA Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I/A
chr19_-_44384291 Show fit	3.56	ENST00000324394.6	ZNF404 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 404
chr22_+_23046750 Show fit	3.53	ENST00000390307.2	IGLV3-22 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr9_+_124103625 Show fit	3.48	ENST00000594963.1	AL161784.1 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr1_+_78470530 Show fit	3.42	ENST00000370763.5	DNAJB4 Ensembl NCBI GeneCards UniProt Show fit	DnaJ (Hsp40) homolog, subfamily B, member 4
chr4_-_186732048 Show fit	3.39	ENST00000448662.2 ENST00000439049.1 ENST00000420158.1 ENST00000431808.1 ENST00000319471.9	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr10_+_94594351 Show fit	3.20	ENST00000371552.4	EXOC6 Ensembl NCBI GeneCards UniProt Show fit	exocyst complex component 6
chr4_-_159080806 Show fit	3.17	ENST00000590648.1	FAM198B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 198, member B
chr6_+_132455526 Show fit	3.13	ENST00000443303.1	LINC01013 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 1013
chr19_+_35417798 Show fit	3.05	ENST00000303586.7 ENST00000439785.1 ENST00000601540.1	ZNF30 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 30
chr9_-_13175823 Show fit	3.00	ENST00000545857.1	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain protein
chr7_+_12726474 Show fit	2.82	ENST00000396662.1 ENST00000356797.3 ENST00000396664.2	ARL4A Ensembl NCBI GeneCards UniProt Show fit	ADP-ribosylation factor-like 4A
chr1_+_163038565 Show fit	2.77	ENST00000421743.2	RGS4 Ensembl NCBI GeneCards UniProt Show fit	regulator of G-protein signaling 4
chrX_+_54947229 Show fit	2.76	ENST00000442098.1 ENST00000430420.1 ENST00000453081.1 ENST00000173898.7 ENST00000319167.8 ENST00000375022.4 ENST00000399736.1 ENST00000440072.1 ENST00000420798.2 ENST00000431115.1 ENST00000440759.1 ENST00000375041.2	TRO Ensembl NCBI GeneCards UniProt Show fit	trophinin
chr11_+_7618413 Show fit	2.73	ENST00000528883.1	PPFIBP2 Ensembl NCBI GeneCards UniProt Show fit	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr17_-_47723943 Show fit	2.71	ENST00000510476.1 ENST00000503676.1	SPOP Ensembl NCBI GeneCards UniProt Show fit	speckle-type POZ protein
chr8_-_93029865 Show fit	2.70	ENST00000422361.2	RUNX1T1 Ensembl NCBI GeneCards UniProt Show fit	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_67057047 Show fit	2.66	ENST00000495634.1 ENST00000453985.2 ENST00000585714.1	ABCA9 Ensembl NCBI GeneCards UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 9
chr6_-_76203345 Show fit	2.58	ENST00000393004.2	FILIP1 Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1
chr3_-_165555200 Show fit	2.54	ENST00000479451.1 ENST00000540653.1 ENST00000488954.1 ENST00000264381.3	BCHE Ensembl NCBI GeneCards UniProt Show fit	butyrylcholinesterase
chr1_+_84630367 Show fit	2.52	ENST00000370680.1	PRKACB Ensembl NCBI GeneCards UniProt Show fit	protein kinase, cAMP-dependent, catalytic, beta
chr7_+_16793160 Show fit	2.50	ENST00000262067.4	TSPAN13 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 13
chr1_+_145524891 Show fit	2.49	ENST00000369304.3	ITGA10 Ensembl NCBI GeneCards UniProt Show fit	integrin, alpha 10
chr1_+_163039143 Show fit	2.48	ENST00000531057.1 ENST00000527809.1 ENST00000367908.4	RGS4 Ensembl NCBI GeneCards UniProt Show fit	regulator of G-protein signaling 4
chr8_+_52730143 Show fit	2.46	ENST00000415643.1	AC090186.1 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr12_-_68696652 Show fit	2.45	ENST00000539972.1	MDM1 Ensembl NCBI GeneCards UniProt Show fit	Mdm1 nuclear protein homolog (mouse)
chr19_-_38916822 Show fit	2.42	ENST00000586305.1	RASGRP4 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 4
chr15_-_70994612 Show fit	2.42	ENST00000558758.1 ENST00000379983.2 ENST00000560441.1	UACA Ensembl NCBI GeneCards UniProt Show fit	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr9_+_71986182 Show fit	2.41	ENST00000303068.7	FAM189A2 Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 189, member A2
chr22_-_29107919 Show fit	2.38	ENST00000434810.1 ENST00000456369.1	CHEK2 Ensembl NCBI GeneCards UniProt Show fit	checkpoint kinase 2
chr13_+_53030107 Show fit	2.32	ENST00000490903.1 ENST00000480747.1	CKAP2 Ensembl NCBI GeneCards UniProt Show fit	cytoskeleton associated protein 2
chr14_+_64680854 Show fit	2.29	ENST00000458046.2	SYNE2 Ensembl NCBI GeneCards UniProt Show fit	spectrin repeat containing, nuclear envelope 2
chr12_+_20963632 Show fit	2.27	ENST00000540853.1 ENST00000261196.2	SLCO1B3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family, member 1B3
chr12_+_19358228 Show fit	2.26	ENST00000424268.1 ENST00000543806.1	PLEKHA5 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing, family A member 5
chr3_+_194406603 Show fit	2.26	ENST00000329759.4	FAM43A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 43, member A
chr4_-_100356551 Show fit	2.24	ENST00000209665.4	ADH7 Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr9_-_21228221 Show fit	2.23	ENST00000413767.2	IFNA17 Ensembl NCBI GeneCards UniProt Show fit	interferon, alpha 17
chr12_+_20963647 Show fit	2.22	ENST00000381545.3	SLCO1B3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family, member 1B3
chr10_+_5135981 Show fit	2.20	ENST00000380554.3	AKR1C3 Ensembl NCBI GeneCards UniProt Show fit	aldo-keto reductase family 1, member C3
chr19_+_35417939 Show fit	2.19	ENST00000601142.1 ENST00000426813.2	ZNF30 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 30
chr9_+_90112117 Show fit	2.10	ENST00000358077.5	DAPK1 Ensembl NCBI GeneCards UniProt Show fit	death-associated protein kinase 1
chr17_-_67057114 Show fit	2.10	ENST00000370732.2	ABCA9 Ensembl NCBI GeneCards UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 9
chr2_-_99279928 Show fit	2.09	ENST00000414521.2	MGAT4A Ensembl NCBI GeneCards UniProt Show fit	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr10_+_35484053 Show fit	2.08	ENST00000487763.1 ENST00000473940.1 ENST00000488328.1 ENST00000356917.5	CREM Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr7_+_80275953 Show fit	2.06	ENST00000538969.1 ENST00000544133.1 ENST00000433696.2	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule (thrombospondin receptor)
chr2_-_68547061 Show fit	2.06	ENST00000263655.3	CNRIP1 Ensembl NCBI GeneCards UniProt Show fit	cannabinoid receptor interacting protein 1
chr3_+_38017264 Show fit	2.06	ENST00000436654.1	CTDSPL Ensembl NCBI GeneCards UniProt Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr20_+_34802295 Show fit	2.05	ENST00000432603.1	EPB41L1 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1-like 1
chr2_+_177134134 Show fit	2.03	ENST00000249442.6 ENST00000392529.2 ENST00000443241.1	MTX2 Ensembl NCBI GeneCards UniProt Show fit	metaxin 2
chr2_-_86094764 Show fit	2.02	ENST00000393808.3	ST3GAL5 Ensembl NCBI GeneCards UniProt Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chrX_+_102192200 Show fit	2.02	ENST00000218249.5	RAB40AL Ensembl NCBI GeneCards UniProt Show fit	RAB40A, member RAS oncogene family-like
chr8_-_81083731 Show fit	2.01	ENST00000379096.5	TPD52 Ensembl NCBI GeneCards UniProt Show fit	tumor protein D52
chrX_-_57164058 Show fit	1.98	ENST00000374906.3	SPIN2A Ensembl NCBI GeneCards UniProt Show fit	spindlin family, member 2A
chrX_+_86772707 Show fit	1.96	ENST00000373119.4	KLHL4 Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 4
chr2_-_191885686 Show fit	1.95	ENST00000432058.1	STAT1 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 1, 91kDa
chr12_-_10007448 Show fit	1.94	ENST00000538152.1	CLEC2B Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 2, member B
chr2_-_89630186 Show fit	1.92	ENST00000390264.2	IGKV2-40 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2-40
chrX_+_10031499 Show fit	1.91	ENST00000454666.1	WWC3 Ensembl NCBI GeneCards UniProt Show fit	WWC family member 3
chr2_+_179184955 Show fit	1.89	ENST00000315022.2	OSBPL6 Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein-like 6
chr14_+_61995722 Show fit	1.87	ENST00000556347.1	RP11-47I22.4 Ensembl NCBI GeneCards UniProt Show fit	RP11-47I22.4
chr15_-_52587945 Show fit	1.86	ENST00000443683.2 ENST00000558479.1 ENST00000261839.7	MYO5C Ensembl NCBI GeneCards UniProt Show fit	myosin VC
chr9_+_71944241 Show fit	1.86	ENST00000257515.8	FAM189A2 Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 189, member A2
chr18_+_3466248 Show fit	1.85	ENST00000581029.1 ENST00000581442.1 ENST00000579007.1	RP11-838N2.4 Ensembl NCBI GeneCards UniProt Show fit	RP11-838N2.4
chr18_-_33647487 Show fit	1.85	ENST00000590898.1 ENST00000357384.4 ENST00000319040.6 ENST00000588737.1 ENST00000399022.4	RPRD1A Ensembl NCBI GeneCards UniProt Show fit	regulation of nuclear pre-mRNA domain containing 1A
chr12_-_7656357 Show fit	1.84	ENST00000396620.3 ENST00000432237.2 ENST00000359156.4	CD163 Ensembl NCBI GeneCards UniProt Show fit	CD163 molecule
chr17_-_295730 Show fit	1.82	ENST00000329099.4	FAM101B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 101, member B
chr10_-_7513904 Show fit	1.82	ENST00000420395.1	RP5-1031D4.2 Ensembl NCBI GeneCards UniProt Show fit	RP5-1031D4.2
chr4_+_90823130 Show fit	1.80	ENST00000508372.1	MMRN1 Ensembl NCBI GeneCards UniProt Show fit	multimerin 1
chr8_-_117043 Show fit	1.79	ENST00000320901.3	OR4F21 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor, family 4, subfamily F, member 21
chr11_+_133938820 Show fit	1.77	ENST00000299106.4 ENST00000529443.2	JAM3 Ensembl NCBI GeneCards UniProt Show fit	junctional adhesion molecule 3
chr17_-_66951474 Show fit	1.76	ENST00000269080.2	ABCA8 Ensembl NCBI GeneCards UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 8
chr9_-_79307096 Show fit	1.76	ENST00000376717.2 ENST00000223609.6 ENST00000443509.2	PRUNE2 Ensembl NCBI GeneCards UniProt Show fit	prune homolog 2 (Drosophila)
chr10_+_35484793 Show fit	1.75	ENST00000488741.1 ENST00000474931.1 ENST00000468236.1 ENST00000344351.5 ENST00000490511.1	CREM Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr1_-_227505289 Show fit	1.74	ENST00000366765.3	CDC42BPA Ensembl NCBI GeneCards UniProt Show fit	CDC42 binding protein kinase alpha (DMPK-like)
chr11_+_133938955 Show fit	1.74	ENST00000534549.1 ENST00000441717.3	JAM3 Ensembl NCBI GeneCards UniProt Show fit	junctional adhesion molecule 3
chr10_+_35456444 Show fit	1.73	ENST00000361599.4	CREM Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element modulator
chr2_-_89247338 Show fit	1.73	ENST00000496168.1	IGKV1-5 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-5
chr7_-_120498357 Show fit	1.71	ENST00000415871.1 ENST00000222747.3 ENST00000430985.1	TSPAN12 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 12
chrX_-_117107542 Show fit	1.71	ENST00000371878.1	KLHL13 Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 13
chr3_-_149293990 Show fit	1.71	ENST00000472417.1	WWTR1 Ensembl NCBI GeneCards UniProt Show fit	WW domain containing transcription regulator 1
chr9_+_21409146 Show fit	1.70	ENST00000380205.1	IFNA8 Ensembl NCBI GeneCards UniProt Show fit	interferon, alpha 8
chr4_+_144354644 Show fit	1.67	ENST00000512843.1	GAB1 Ensembl NCBI GeneCards UniProt Show fit	GRB2-associated binding protein 1
chr20_+_11008811 Show fit	1.65	ENST00000537362.1	C20orf187 Ensembl NCBI GeneCards UniProt Show fit	chromosome 20 open reading frame 187
chr1_+_89829610 Show fit	1.65	ENST00000370456.4 ENST00000535065.1	GBP6 Ensembl NCBI GeneCards UniProt Show fit	guanylate binding protein family, member 6
chr1_+_95616933 Show fit	1.65	ENST00000604203.1	RP11-57H12.6 Ensembl NCBI GeneCards UniProt Show fit	TMEM56-RWDD3 readthrough
chr5_+_140227048 Show fit	1.64	ENST00000532602.1	PCDHA9 Ensembl NCBI GeneCards UniProt Show fit	protocadherin alpha 9
chr4_-_138453606 Show fit	1.63	ENST00000412923.2 ENST00000344876.4 ENST00000507846.1 ENST00000510305.1	PCDH18 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 18
chr12_+_79439405 Show fit	1.62	ENST00000552744.1	SYT1 Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin I
chr11_-_1629693 Show fit	1.61	ENST00000399685.1	KRTAP5-3 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 5-3
chr7_+_80275752 Show fit	1.61	ENST00000419819.2	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule (thrombospondin receptor)
chr2_+_1418154 Show fit	1.61	ENST00000423320.1 ENST00000382198.1	TPO Ensembl NCBI GeneCards UniProt Show fit	thyroid peroxidase
chr1_-_153066998 Show fit	1.60	ENST00000368750.3	SPRR2E Ensembl NCBI GeneCards UniProt Show fit	small proline-rich protein 2E
chr12_+_60083118 Show fit	1.59	ENST00000261187.4 ENST00000543448.1	SLC16A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 (monocarboxylate transporter), member 7
chr17_+_3379284 Show fit	1.59	ENST00000263080.2	ASPA Ensembl NCBI GeneCards UniProt Show fit	aspartoacylase
chr5_+_140165876 Show fit	1.58	ENST00000504120.2 ENST00000394633.3 ENST00000378133.3	PCDHA1 Ensembl NCBI GeneCards UniProt Show fit	protocadherin alpha 1
chr8_+_67104323 Show fit	1.58	ENST00000518412.1 ENST00000518035.1 ENST00000517725.1	LINC00967 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 967
chr9_+_2159850 Show fit	1.58	ENST00000416751.1	SMARCA2 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_59012365 Show fit	1.57	ENST00000456980.1 ENST00000482274.2 ENST00000453710.1 ENST00000419242.1 ENST00000358603.2 ENST00000371226.3 ENST00000426139.1	OMA1 Ensembl NCBI GeneCards UniProt Show fit	OMA1 zinc metallopeptidase
chr19_+_35417844 Show fit	1.57	ENST00000601957.1	ZNF30 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 30
chr12_+_79258547 Show fit	1.57	ENST00000457153.2	SYT1 Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin I
chr2_+_190722119 Show fit	1.56	ENST00000452382.1	PMS1 Ensembl NCBI GeneCards UniProt Show fit	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
chr5_-_111093759 Show fit	1.56	ENST00000509979.1 ENST00000513100.1 ENST00000508161.1 ENST00000455559.2	NREP Ensembl NCBI GeneCards UniProt Show fit	neuronal regeneration related protein
chr19_-_44388116 Show fit	1.56	ENST00000587539.1	ZNF404 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 404
chrX_-_77150911 Show fit	1.56	ENST00000373336.3	MAGT1 Ensembl NCBI GeneCards UniProt Show fit	magnesium transporter 1
chr12_+_80750134 Show fit	1.55	ENST00000546620.1	OTOGL Ensembl NCBI GeneCards UniProt Show fit	otogelin-like
chr13_+_103459704 Show fit	1.55	ENST00000602836.1	BIVM-ERCC5 Ensembl NCBI GeneCards UniProt Show fit	BIVM-ERCC5 readthrough
chr11_+_58390132 Show fit	1.55	ENST00000361987.4	CNTF Ensembl NCBI GeneCards UniProt Show fit	ciliary neurotrophic factor
chr12_-_30887948 Show fit	1.54	ENST00000433722.2	CAPRIN2 Ensembl NCBI GeneCards UniProt Show fit	caprin family member 2
chr4_-_110723134 Show fit	1.52	ENST00000510800.1 ENST00000512148.1	CFI Ensembl NCBI GeneCards UniProt Show fit	complement factor I
chr20_-_33732952 Show fit	1.52	ENST00000541621.1	EDEM2 Ensembl NCBI GeneCards UniProt Show fit	ER degradation enhancer, mannosidase alpha-like 2
chr7_+_107224364 Show fit	1.51	ENST00000491150.1	BCAP29 Ensembl NCBI GeneCards UniProt Show fit	B-cell receptor-associated protein 29
chr19_-_38916839 Show fit	1.51	ENST00000433821.2 ENST00000426920.2 ENST00000587753.1 ENST00000454404.2 ENST00000293062.9	RASGRP4 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 4
chr6_-_28321971 Show fit	1.51	ENST00000396838.2 ENST00000426434.1 ENST00000434036.1 ENST00000439628.1	ZSCAN31 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and SCAN domain containing 31
chr6_+_24775153 Show fit	1.50	ENST00000356509.3 ENST00000230056.3	GMNN Ensembl NCBI GeneCards UniProt Show fit	geminin, DNA replication inhibitor
chr22_+_22936998 Show fit	1.50	ENST00000390303.2	IGLV3-32 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-32 (non-functional)
chr10_+_5488564 Show fit	1.50	ENST00000449083.1 ENST00000380359.3	NET1 Ensembl NCBI GeneCards UniProt Show fit	neuroepithelial cell transforming 1
chr15_-_20193370 Show fit	1.47	ENST00000558565.2	IGHV3OR15-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr17_-_67057203 Show fit	1.47	ENST00000340001.4	ABCA9 Ensembl NCBI GeneCards UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 9
chr11_+_121461097 Show fit	1.47	ENST00000527934.1	SORL1 Ensembl NCBI GeneCards UniProt Show fit	sortilin-related receptor, L(DLR class) A repeats containing
chr5_+_61874562 Show fit	1.46	ENST00000334994.5 ENST00000409534.1	LRRC70 Ensembl NCBI GeneCards UniProt Show fit IPO11 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 70 importin 11
chr1_+_76540386 Show fit	1.46	ENST00000328299.3	ST6GALNAC3 Ensembl NCBI GeneCards UniProt Show fit	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr8_-_66474884 Show fit	1.45	ENST00000520902.1	CTD-3025N20.2 Ensembl NCBI GeneCards UniProt Show fit	CTD-3025N20.2
chr8_-_81787006 Show fit	1.45	ENST00000327835.3	ZNF704 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 704
chr11_+_74459876 Show fit	1.44	ENST00000299563.4	RNF169 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 169
chr2_-_191878162 Show fit	1.43	ENST00000540176.1	STAT1 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 1, 91kDa
chr2_-_170430366 Show fit	1.43	ENST00000453153.2 ENST00000445210.1	FASTKD1 Ensembl NCBI GeneCards UniProt Show fit	FAST kinase domains 1
chr8_-_4852494 Show fit	1.42	ENST00000520002.1 ENST00000602557.1	CSMD1 Ensembl NCBI GeneCards UniProt Show fit	CUB and Sushi multiple domains 1
chr12_-_15114658 Show fit	1.41	ENST00000542276.1	ARHGDIB Ensembl NCBI GeneCards UniProt Show fit	Rho GDP dissociation inhibitor (GDI) beta
chr18_+_6834472 Show fit	1.41	ENST00000581099.1 ENST00000419673.2 ENST00000531294.1	ARHGAP28 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 28
chrX_-_10645773 Show fit	1.41	ENST00000453318.2	MID1 Ensembl NCBI GeneCards UniProt Show fit	midline 1 (Opitz/BBB syndrome)
chr2_-_183106641 Show fit	1.37	ENST00000346717.4	PDE1A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 1A, calmodulin-dependent
chr4_+_88532028 Show fit	1.37	ENST00000282478.7	DSPP Ensembl NCBI GeneCards UniProt Show fit	dentin sialophosphoprotein
chr2_+_173600514 Show fit	1.37	ENST00000264111.6	RAPGEF4 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor (GEF) 4
chr5_+_140579162 Show fit	1.36	ENST00000536699.1 ENST00000354757.3	PCDHB11 Ensembl NCBI GeneCards UniProt Show fit	protocadherin beta 11
chr3_+_141457030 Show fit	1.36	ENST00000273480.3	RNF7 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 7
chr8_-_27941380 Show fit	1.35	ENST00000413272.2 ENST00000341513.6	NUGGC Ensembl NCBI GeneCards UniProt Show fit	nuclear GTPase, germinal center associated
chr12_+_60058458 Show fit	1.35	ENST00000548610.1	SLC16A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 (monocarboxylate transporter), member 7
chr18_-_52989217 Show fit	1.34	ENST00000570287.2	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr5_+_140220769 Show fit	1.33	ENST00000531613.1 ENST00000378123.3	PCDHA8 Ensembl NCBI GeneCards UniProt Show fit	protocadherin alpha 8
chr2_+_179149636 Show fit	1.33	ENST00000409631.1	OSBPL6 Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein-like 6
chr2_+_189839046 Show fit	1.31	ENST00000304636.3 ENST00000317840.5	COL3A1 Ensembl NCBI GeneCards UniProt Show fit	collagen, type III, alpha 1
chr2_+_66662510 Show fit	1.31	ENST00000272369.9 ENST00000407092.2	MEIS1 Ensembl NCBI GeneCards UniProt Show fit	Meis homeobox 1
chr5_-_55412774 Show fit	1.30	ENST00000434982.2	ANKRD55 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 55
chr7_-_121784285 Show fit	1.30	ENST00000417368.2	AASS Ensembl NCBI GeneCards UniProt Show fit	aminoadipate-semialdehyde synthase
chr14_+_45605157 Show fit	1.30	ENST00000542564.2	FANCM Ensembl NCBI GeneCards UniProt Show fit	Fanconi anemia, complementation group M
chr5_-_9630463 Show fit	1.29	ENST00000382492.2	TAS2R1 Ensembl NCBI GeneCards UniProt Show fit	taste receptor, type 2, member 1
chr21_+_17792672 Show fit	1.29	ENST00000602620.1	LINC00478 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 478
chr17_+_35851570 Show fit	1.28	ENST00000394386.1	DUSP14 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 14
chr9_-_21077939 Show fit	1.28	ENST00000380232.2	IFNB1 Ensembl NCBI GeneCards UniProt Show fit	interferon, beta 1, fibroblast
chrX_-_24045303 Show fit	1.28	ENST00000328046.8	KLHL15 Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 15
chr5_-_135290705 Show fit	1.27	ENST00000274507.1	LECT2 Ensembl NCBI GeneCards UniProt Show fit	leukocyte cell-derived chemotaxin 2
chr1_+_196621002 Show fit	1.27	ENST00000367429.4 ENST00000439155.2	CFH Ensembl NCBI GeneCards UniProt Show fit	complement factor H
chrX_+_138612889 Show fit	1.25	ENST00000218099.2 ENST00000394090.2	F9 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor IX
chr4_+_108911036 Show fit	1.25	ENST00000505878.1	HADH Ensembl NCBI GeneCards UniProt Show fit	hydroxyacyl-CoA dehydrogenase
chr12_+_9144626 Show fit	1.25	ENST00000543895.1	KLRG1 Ensembl NCBI GeneCards UniProt Show fit	killer cell lectin-like receptor subfamily G, member 1
chr19_+_18208603 Show fit	1.24	ENST00000262811.6	MAST3 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase 3
chr12_-_14849470 Show fit	1.24	ENST00000261170.3	GUCY2C Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 2C (heat stable enterotoxin receptor)
chr1_-_110933611 Show fit	1.23	ENST00000472422.2 ENST00000437429.2	SLC16A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16, member 4
chr1_-_20503917 Show fit	1.22	ENST00000429261.2	PLA2G2C Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2, group IIC
chr6_-_29324054 Show fit	1.22	ENST00000543825.1	OR5V1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor, family 5, subfamily V, member 1
chr11_-_82708519 Show fit	1.22	ENST00000534301.1	RAB30 Ensembl NCBI GeneCards UniProt Show fit	RAB30, member RAS oncogene family
chr16_+_56995854 Show fit	1.22	ENST00000566128.1	CETP Ensembl NCBI GeneCards UniProt Show fit	cholesteryl ester transfer protein, plasma
chr3_-_141747950 Show fit	1.22	ENST00000497579.1	TFDP2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-2 (E2F dimerization partner 2)
chr7_-_93520191 Show fit	1.22	ENST00000545378.1	TFPI2 Ensembl NCBI GeneCards UniProt Show fit	tissue factor pathway inhibitor 2
chr14_+_89290965 Show fit	1.21	ENST00000345383.5 ENST00000536576.1 ENST00000346301.4 ENST00000338104.6 ENST00000354441.6 ENST00000380656.2 ENST00000556651.1 ENST00000554686.1	TTC8 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 8
chr12_+_101988627 Show fit	1.21	ENST00000547405.1 ENST00000452455.2 ENST00000441232.1 ENST00000360610.2 ENST00000392934.3 ENST00000547509.1 ENST00000361685.2 ENST00000549145.1 ENST00000553190.1	MYBPC1 Ensembl NCBI GeneCards UniProt Show fit	myosin binding protein C, slow type
chr2_-_44588679 Show fit	1.21	ENST00000409411.1	PREPL Ensembl NCBI GeneCards UniProt Show fit	prolyl endopeptidase-like
chr2_-_44588694 Show fit	1.20	ENST00000409957.1	PREPL Ensembl NCBI GeneCards UniProt Show fit	prolyl endopeptidase-like
chr1_+_28764653 Show fit	1.20	ENST00000373836.3	PHACTR4 Ensembl NCBI GeneCards UniProt Show fit	phosphatase and actin regulator 4
chr7_-_86595190 Show fit	1.19	ENST00000398276.2 ENST00000416314.1 ENST00000425689.1	KIAA1324L Ensembl NCBI GeneCards UniProt Show fit	KIAA1324-like
chr1_+_367640 Show fit	1.19	ENST00000426406.1	OR4F29 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor, family 4, subfamily F, member 29
chr11_-_19082216 Show fit	1.19	ENST00000329773.2	MRGPRX2 Ensembl NCBI GeneCards UniProt Show fit	MAS-related GPR, member X2
chrX_+_36065053 Show fit	1.19	ENST00000313548.4	CHDC2 Ensembl NCBI GeneCards UniProt Show fit	calponin homology domain containing 2
chr1_+_12227035 Show fit	1.19	ENST00000376259.3 ENST00000536782.1	TNFRSF1B Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor receptor superfamily, member 1B
chr15_-_55657428 Show fit	1.19	ENST00000568543.1	CCPG1 Ensembl NCBI GeneCards UniProt Show fit	cell cycle progression 1
chr11_+_7110165 Show fit	1.18	ENST00000306904.5	RBMXL2 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein, X-linked-like 2
chr2_+_90108504 Show fit	1.18	ENST00000390271.2	IGKV6D-41 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6D-41 (non-functional)
chr2_-_44588624 Show fit	1.18	ENST00000438314.1 ENST00000409936.1	PREPL Ensembl NCBI GeneCards UniProt Show fit	prolyl endopeptidase-like
chr17_+_7788104 Show fit	1.17	ENST00000380358.4	CHD3 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 3
chr11_-_104916034 Show fit	1.16	ENST00000528513.1 ENST00000375706.2 ENST00000375704.3	CARD16 Ensembl NCBI GeneCards UniProt Show fit	caspase recruitment domain family, member 16
chr12_-_118406028 Show fit	1.16	ENST00000425217.1	KSR2 Ensembl NCBI GeneCards UniProt Show fit	kinase suppressor of ras 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXL1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	74.8	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
2.0	13.8	GO:0097338	response to clozapine(GO:0097338)
1.4	4.2	GO:0021558	trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
1.3	2.5	GO:0014016	neuroblast differentiation(GO:0014016)
1.2	3.6	GO:0010430	fatty acid omega-oxidation(GO:0010430)
1.1	3.2	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.8	3.4	GO:0072308	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.8	2.4	GO:1903926	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.7	4.9	GO:0072564	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6	4.4	GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6	2.4	GO:0016095	polyprenol catabolic process(GO:0016095)
0.6	4.1	GO:0071461	cellular response to redox state(GO:0071461)
0.6	2.3	GO:0046373	arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.5	1.1	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.5	1.6	GO:0006533	aspartate catabolic process(GO:0006533)
0.5	1.6	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.5	1.5	GO:0036512	trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.5	10.8	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.5	1.5	GO:1902955	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.5	1.4	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.4	2.5	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4	1.2	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.4	2.0	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.4	3.5	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.4	3.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.4	2.3	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.4	1.9	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.4	2.9	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.3	9.8	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3	1.0	GO:0046707	IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.3	1.3	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.3	1.3	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
0.3	5.3	GO:0015871	choline transport(GO:0015871)
0.3	0.8	GO:2000502	negative regulation of natural killer cell chemotaxis(GO:2000502)
0.3	0.8	GO:0030264	nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.3	1.9	GO:0008218	bioluminescence(GO:0008218)
0.3	0.8	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3	1.0	GO:2000360	negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.2	1.5	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.2	0.7	GO:1904387	cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.2	1.2	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2	0.9	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678) swimming behavior(GO:0036269)
0.2	0.2	GO:0086092	regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.2	1.2	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.2	2.9	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.2	0.4	GO:0021817	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.2	1.1	GO:0006543	glutamine catabolic process(GO:0006543)
0.2	1.3	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.2	1.5	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.2	1.1	GO:0006696	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2	0.6	GO:0031247	actin rod assembly(GO:0031247)
0.2	0.6	GO:0034059	response to anoxia(GO:0034059)
0.2	1.2	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.2	1.2	GO:0050893	sensory processing(GO:0050893)
0.2	1.0	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2	0.8	GO:0001970	positive regulation of activation of membrane attack complex(GO:0001970)
0.2	0.8	GO:1900063	regulation of peroxisome organization(GO:1900063)
0.2	2.5	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.2	1.7	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.2	3.0	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2	0.7	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.2	0.6	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.2	0.5	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.2	1.1	GO:0019418	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2	1.8	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2	0.7	GO:0046462	monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2	0.5	GO:0001812	positive regulation of type I hypersensitivity(GO:0001812)
0.2	1.9	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.2	1.3	GO:0019236	response to pheromone(GO:0019236)
0.2	0.8	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2	2.0	GO:0055091	phospholipid homeostasis(GO:0055091)
0.2	1.0	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2	0.5	GO:0014839	myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.2	0.3	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2	0.5	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2	1.1	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
0.2	0.5	GO:0061010	negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.1	0.9	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.4	GO:0032203	telomere formation via telomerase(GO:0032203)
0.1	0.3	GO:1901526	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1	0.4	GO:0071529	cementum mineralization(GO:0071529)
0.1	0.4	GO:1904719	excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1	0.3	GO:0036215	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1	0.7	GO:0050917	sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1	0.4	GO:0036060	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1	1.3	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	1.7	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	2.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	6.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.4	GO:0001694	histamine biosynthetic process(GO:0001694)
0.1	0.3	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1	0.8	GO:0006789	bilirubin conjugation(GO:0006789)
0.1	1.2	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	1.9	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1	0.4	GO:0098759	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1	0.7	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1	1.9	GO:0006449	regulation of translational termination(GO:0006449)
0.1	1.0	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	0.8	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1	0.4	GO:0042214	terpene metabolic process(GO:0042214)
0.1	1.0	GO:0018406	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.9	GO:0048014	Tie signaling pathway(GO:0048014)
0.1	1.2	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	0.4	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
0.1	0.4	GO:1904048	regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1	0.8	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.1	0.6	GO:0038155	interleukin-23-mediated signaling pathway(GO:0038155)
0.1	1.5	GO:0051451	myoblast migration(GO:0051451)
0.1	0.3	GO:0001080	nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1	0.6	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1	2.0	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.2	GO:0032077	positive regulation of deoxyribonuclease activity(GO:0032077)
0.1	0.7	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.1	0.4	GO:0071047	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) U1 snRNA 3'-end processing(GO:0034473) U4 snRNA 3'-end processing(GO:0034475) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1	1.6	GO:0015693	magnesium ion transport(GO:0015693)
0.1	0.3	GO:0030644	antibiotic metabolic process(GO:0016999) cellular chloride ion homeostasis(GO:0030644)
0.1	4.3	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	0.4	GO:0006740	NADPH regeneration(GO:0006740)
0.1	0.4	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.1	0.9	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.1	0.4	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.1	0.4	GO:0005986	sucrose biosynthetic process(GO:0005986)
0.1	3.9	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.1	0.6	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	1.6	GO:0070933	histone H4 deacetylation(GO:0070933)
0.1	1.4	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	1.1	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	0.7	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.1	0.3	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.1	0.6	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.1	1.3	GO:0033623	regulation of integrin activation(GO:0033623)
0.1	0.4	GO:0010826	negative regulation of centrosome duplication(GO:0010826)
0.1	1.7	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.1	0.9	GO:0034128	negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1	0.9	GO:0071351	interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1	3.3	GO:0060074	synapse maturation(GO:0060074)
0.1	0.8	GO:1904424	regulation of GTP binding(GO:1904424)
0.1	0.8	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1	0.4	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.1	0.4	GO:0033383	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
0.1	0.4	GO:0071400	cellular response to oleic acid(GO:0071400)
0.1	2.0	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.1	1.5	GO:2000480	negative regulation of meiotic nuclear division(GO:0045835) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.9	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	1.4	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.1	0.3	GO:0052053	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1	0.3	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1	3.4	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.1	11.6	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	1.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.1	0.9	GO:0006621	protein retention in ER lumen(GO:0006621)
0.1	0.5	GO:0035633	maintenance of blood-brain barrier(GO:0035633)
0.1	0.9	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1	3.8	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1	0.8	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.1	1.4	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.4	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	2.4	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.1	0.2	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1	1.7	GO:0097503	sialylation(GO:0097503)
0.1	3.5	GO:0050873	brown fat cell differentiation(GO:0050873)
0.1	0.1	GO:0046606	negative regulation of centrosome cycle(GO:0046606)
0.1	1.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.4	GO:0046878	positive regulation of saliva secretion(GO:0046878)
0.1	0.5	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.1	0.3	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	1.2	GO:0008298	intracellular mRNA localization(GO:0008298)
0.1	0.3	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1	0.3	GO:0051552	flavone metabolic process(GO:0051552)
0.1	0.7	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	0.8	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.1	1.5	GO:0006590	thyroid hormone generation(GO:0006590)
0.1	0.5	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1	0.2	GO:0045204	MAPK export from nucleus(GO:0045204)
0.1	0.3	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.1	1.4	GO:0045116	protein neddylation(GO:0045116)
0.1	0.6	GO:0006600	creatine metabolic process(GO:0006600)
0.1	0.4	GO:0036101	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1	0.2	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1	0.6	GO:0003356	regulation of cilium beat frequency(GO:0003356)
0.1	0.3	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1	0.2	GO:0003104	positive regulation of glomerular filtration(GO:0003104) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1	0.4	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	2.9	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.1	0.5	GO:0015889	cobalamin transport(GO:0015889)
0.1	1.7	GO:0010842	retina layer formation(GO:0010842)
0.1	0.3	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.1	0.6	GO:0042908	xenobiotic transport(GO:0042908)
0.1	0.5	GO:0035881	amacrine cell differentiation(GO:0035881)
0.1	0.4	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	0.3	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.1	0.8	GO:0055022	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.1	0.9	GO:0086069	bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1	2.5	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.1	1.6	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1	0.4	GO:0002084	protein depalmitoylation(GO:0002084)
0.1	1.6	GO:2000780	negative regulation of double-strand break repair(GO:2000780)
0.1	2.0	GO:0006298	mismatch repair(GO:0006298)
0.1	0.5	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.1	1.2	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1	0.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.1	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.1	0.6	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	9.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.5	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1	1.7	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.1	0.2	GO:0030185	nitric oxide transport(GO:0030185)
0.1	4.9	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.1	0.8	GO:0070986	left/right axis specification(GO:0070986)
0.1	0.6	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	1.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.6	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	3.1	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.2	GO:0030070	insulin processing(GO:0030070)
0.0	0.3	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.4	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:0097032	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0	0.9	GO:0032201	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) telomere maintenance via semi-conservative replication(GO:0032201)
0.0	0.4	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.5	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	0.2	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.2	GO:0007525	somatic muscle development(GO:0007525)
0.0	2.1	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.2	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0	1.0	GO:0048240	sperm capacitation(GO:0048240)
0.0	1.0	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0	0.8	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.6	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0	0.3	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.2	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.3	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.3	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.3	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	1.6	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.4	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.7	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	4.8	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0	0.3	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.6	GO:0044849	estrous cycle(GO:0044849)
0.0	1.1	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.0	0.2	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.3	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0	0.1	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	8.2	GO:0031032	actomyosin structure organization(GO:0031032)
0.0	0.4	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.5	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.3	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.3	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) dUMP metabolic process(GO:0046078)
0.0	0.6	GO:0001946	lymphangiogenesis(GO:0001946)
0.0	1.9	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	1.2	GO:0030431	sleep(GO:0030431)
0.0	1.3	GO:0048806	genitalia development(GO:0048806)
0.0	1.3	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.4	GO:0015747	urate transport(GO:0015747)
0.0	0.3	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.3	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.8	GO:0006284	base-excision repair(GO:0006284)
0.0	0.0	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.0	0.1	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0	0.7	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.0	0.2	GO:0072642	interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0	0.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0	0.2	GO:0035865	cellular response to potassium ion(GO:0035865)
0.0	0.8	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.1	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.0	0.0	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.0	0.2	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.2	GO:0001180	transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0	0.9	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.0	0.5	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.3	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	3.6	GO:0000910	cytokinesis(GO:0000910)
0.0	0.5	GO:2001222	regulation of neuron migration(GO:2001222)
0.0	0.2	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0	0.7	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	1.2	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.3	GO:0030207	chondroitin sulfate catabolic process(GO:0030207)
0.0	0.1	GO:0070943	neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0	0.1	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.1	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0	0.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.1	GO:0048698	abscission(GO:0009838) negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0	0.2	GO:0071389	cellular response to mineralocorticoid stimulus(GO:0071389)
0.0	0.3	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.4	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.1	GO:1990418	response to insulin-like growth factor stimulus(GO:1990418)
0.0	0.3	GO:0051601	exocyst localization(GO:0051601)
0.0	0.2	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.4	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
0.0	0.2	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.5	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.0	0.5	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	3.8	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	0.1	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.0	0.4	GO:0009081	branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0	0.0	GO:0036292	DNA rewinding(GO:0036292)
0.0	0.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.3	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	0.1	GO:2000373	phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.3	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.6	GO:2000785	regulation of autophagosome assembly(GO:2000785)
0.0	0.2	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651) dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	1.7	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.1	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.0	0.8	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.3	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.7	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.1	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.2	GO:0009651	response to salt stress(GO:0009651)
0.0	0.2	GO:1902358	sulfate transmembrane transport(GO:1902358)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:2000318	positive regulation of T-helper 17 type immune response(GO:2000318)
0.0	0.6	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.1	GO:0060011	progesterone biosynthetic process(GO:0006701) Sertoli cell proliferation(GO:0060011)
0.0	0.7	GO:0003009	skeletal muscle contraction(GO:0003009)
0.0	1.7	GO:0007286	spermatid development(GO:0007286)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0032324	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.2	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.0	0.2	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.2	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.3	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.2	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.4	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.3	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.3	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.7	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	0.1	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.2	GO:0007413	axonal fasciculation(GO:0007413)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.5	GO:0034680	integrin alpha10-beta1 complex(GO:0034680)
0.7	15.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.6	3.2	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.5	1.6	GO:0005656	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.5	1.5	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.5	1.4	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.4	1.3	GO:0071821	FANCM-MHF complex(GO:0071821)
0.3	6.5	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.3	4.4	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.3	3.8	GO:0005641	nuclear envelope lumen(GO:0005641)
0.2	0.7	GO:0017109	glutamate-cysteine ligase complex(GO:0017109)
0.2	1.3	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.2	0.2	GO:0005712	chiasma(GO:0005712)
0.2	0.6	GO:0071746	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.2	1.6	GO:0032389	MutLalpha complex(GO:0032389)
0.2	0.6	GO:0000814	ESCRT II complex(GO:0000814)
0.2	0.7	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.2	0.9	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.2	2.2	GO:0034464	BBSome(GO:0034464)
0.2	5.8	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	0.9	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	1.2	GO:0043196	varicosity(GO:0043196)
0.1	0.4	GO:0042022	interleukin-12 receptor complex(GO:0042022)
0.1	1.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.1	1.0	GO:0036128	CatSper complex(GO:0036128)
0.1	1.9	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.5	GO:0031251	PAN complex(GO:0031251)
0.1	5.4	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	0.6	GO:0002079	inner acrosomal membrane(GO:0002079)
0.1	1.6	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.9	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.1	11.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	0.5	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.1	2.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.4	GO:0097224	sperm connecting piece(GO:0097224)
0.1	0.5	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	3.5	GO:0000145	exocyst(GO:0000145)
0.1	2.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.1	1.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.4	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.1	2.4	GO:0032982	myosin filament(GO:0032982)
0.1	0.7	GO:0005579	membrane attack complex(GO:0005579)
0.1	0.5	GO:0033263	CORVET complex(GO:0033263)
0.1	0.6	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.1	0.4	GO:0070876	SOSS complex(GO:0070876)
0.1	0.2	GO:0072536	interleukin-23 receptor complex(GO:0072536)
0.1	1.6	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	1.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	0.4	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	57.2	GO:0031012	extracellular matrix(GO:0031012)
0.1	0.4	GO:1990761	growth cone lamellipodium(GO:1990761)
0.1	0.7	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	1.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.6	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1	0.5	GO:0032437	cuticular plate(GO:0032437)
0.1	1.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.5	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.5	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	1.1	GO:0042555	MCM complex(GO:0042555)
0.1	0.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	1.6	GO:0071564	npBAF complex(GO:0071564)
0.1	0.8	GO:0044327	dendritic spine head(GO:0044327)
0.1	0.4	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	1.1	GO:0036038	MKS complex(GO:0036038)
0.1	0.3	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.5	GO:0033269	internode region of axon(GO:0033269)
0.1	0.8	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.3	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.1	0.2	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	1.5	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	0.4	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.8	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0019008	molybdopterin synthase complex(GO:0019008)
0.0	0.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	1.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.3	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.0	0.8	GO:0035869	ciliary transition zone(GO:0035869)
0.0	0.2	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.6	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.2	GO:1990246	uniplex complex(GO:1990246)
0.0	4.2	GO:0042641	actomyosin(GO:0042641)
0.0	0.7	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0097679	other organism cytoplasm(GO:0097679)
0.0	0.3	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0	1.4	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	1.7	GO:0009925	basal plasma membrane(GO:0009925)
0.0	1.0	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	1.2	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.4	GO:0046930	pore complex(GO:0046930)
0.0	0.4	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	2.2	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	7.2	GO:0030018	Z disc(GO:0030018)
0.0	1.2	GO:0042629	mast cell granule(GO:0042629)
0.0	0.9	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.4	GO:0032797	SMN complex(GO:0032797)
0.0	2.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	1.8	GO:0005801	cis-Golgi network(GO:0005801)
0.0	1.7	GO:0001533	cornified envelope(GO:0001533)
0.0	0.8	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.6	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.1	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.0	0.6	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	1.0	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.6	GO:0005861	troponin complex(GO:0005861)
0.0	0.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.6	GO:0097546	ciliary base(GO:0097546)
0.0	0.2	GO:0045180	basal cortex(GO:0045180)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.3	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.2	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.1	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0	0.4	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.3	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	1.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.6	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0	0.9	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	2.6	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.2	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.8	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.0	0.3	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.3	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.4	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0	7.2	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	1.1	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.4	GO:0031941	filamentous actin(GO:0031941)
0.0	0.7	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0	1.7	GO:0005814	centriole(GO:0005814)
0.0	0.2	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.4	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.2	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.5	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	1.6	GO:0072562	blood microparticle(GO:0072562)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.5	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.2	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.2	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	2.7	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	4.9	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.8	3.2	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.8	13.8	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.7	2.9	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.7	10.8	GO:0005132	type I interferon receptor binding(GO:0005132)
0.7	2.0	GO:0017129	triglyceride binding(GO:0017129)
0.6	2.5	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.6	5.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.6	2.3	GO:0046556	alpha-L-arabinofuranosidase activity(GO:0046556)
0.6	2.3	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.5	0.5	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.5	2.8	GO:0030348	syntaxin-3 binding(GO:0030348)
0.4	1.3	GO:0016503	pheromone receptor activity(GO:0016503)
0.4	2.5	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4	8.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.4	10.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.3	4.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3	2.0	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.3	1.3	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.3	5.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.3	0.9	GO:0033754	indoleamine 2,3-dioxygenase activity(GO:0033754)
0.3	1.8	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.3	0.9	GO:0047086	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.3	1.7	GO:0001594	trace-amine receptor activity(GO:0001594)
0.3	1.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.3	0.8	GO:0017082	mineralocorticoid receptor activity(GO:0017082)
0.3	1.6	GO:0004447	iodide peroxidase activity(GO:0004447)
0.3	1.1	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2	0.7	GO:0004357	glutamate-cysteine ligase activity(GO:0004357)
0.2	0.9	GO:0032395	MHC class II receptor activity(GO:0032395)
0.2	3.0	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2	1.4	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.2	1.1	GO:0004359	glutaminase activity(GO:0004359)
0.2	0.6	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.2	0.6	GO:0004531	deoxyribonuclease II activity(GO:0004531)
0.2	74.0	GO:0003714	transcription corepressor activity(GO:0003714)
0.2	1.0	GO:0043262	ADP-sugar diphosphatase activity(GO:0019144) adenosine-diphosphatase activity(GO:0043262)
0.2	1.4	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2	4.3	GO:0033038	bitter taste receptor activity(GO:0033038)
0.2	4.5	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.2	1.2	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2	0.9	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.2	0.8	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2	0.8	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2	5.0	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.2	0.6	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.2	2.4	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.9	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	0.4	GO:0016517	interleukin-12 receptor activity(GO:0016517)
0.1	2.0	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.4	GO:0016652	NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1	0.9	GO:0031013	troponin I binding(GO:0031013)
0.1	0.4	GO:0019959	interleukin-8 binding(GO:0019959)
0.1	0.4	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1	0.9	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	1.1	GO:0004064	arylesterase activity(GO:0004064)
0.1	0.4	GO:0070052	collagen V binding(GO:0070052)
0.1	2.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.4	GO:0097259	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1	0.4	GO:0033149	FFAT motif binding(GO:0033149)
0.1	0.5	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.5	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1	1.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.7	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.4	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1	0.4	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1	3.1	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	2.2	GO:0030983	mismatched DNA binding(GO:0030983)
0.1	1.8	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	1.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	0.6	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.4	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.1	2.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1	0.4	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1	0.9	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.8	GO:0000405	bubble DNA binding(GO:0000405)
0.1	0.4	GO:0097363	protein O-GlcNAc transferase activity(GO:0097363)
0.1	5.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	0.3	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1	0.9	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	4.3	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	0.4	GO:0005042	netrin receptor activity(GO:0005042)
0.1	0.5	GO:0042806	fucose binding(GO:0042806)
0.1	0.4	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1	0.9	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	1.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.6	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	1.7	GO:0031432	titin binding(GO:0031432)
0.1	1.5	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.9	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.6	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1	0.2	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	0.8	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	1.0	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1	1.8	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	1.9	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.2	GO:0042019	interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1	0.3	GO:0070404	NADH binding(GO:0070404)
0.1	0.4	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	0.2	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.1	0.5	GO:0001093	TFIIB-class transcription factor binding(GO:0001093)
0.1	2.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	1.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	0.3	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1	1.7	GO:0000339	RNA cap binding(GO:0000339)
0.1	0.5	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	1.2	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.1	0.3	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1	0.3	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1	0.5	GO:0019863	immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.1	2.6	GO:0015248	sterol transporter activity(GO:0015248)
0.1	4.6	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.2	GO:0005124	scavenger receptor binding(GO:0005124)
0.1	1.2	GO:0042923	neuropeptide binding(GO:0042923)
0.1	0.3	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.1	0.6	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1	1.5	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	1.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.5	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	0.4	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.1	1.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	0.6	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.1	0.3	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1	0.4	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.7	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.3	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.1	1.9	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	0.3	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.6	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.6	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0	1.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	6.0	GO:0051087	chaperone binding(GO:0051087)
0.0	0.4	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0035671	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0	5.7	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.3	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.3	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.9	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.2	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.4	GO:0032190	acrosin binding(GO:0032190)
0.0	0.5	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.3	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	1.0	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.3	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	0.8	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.8	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.4	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.4	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.4	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.4	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	1.0	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.1	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.0	0.1	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.0	0.5	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	4.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	2.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	1.1	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.6	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.9	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.7	GO:0031005	filamin binding(GO:0031005)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.7	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.4	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	1.2	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.3	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.4	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.4	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	1.2	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.2	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.4	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.3	GO:0004849	uridine kinase activity(GO:0004849)
0.0	1.0	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.5	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	4.9	GO:0003823	antigen binding(GO:0003823)
0.0	1.4	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	0.3	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.4	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.8	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.2	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.7	GO:0005521	lamin binding(GO:0005521)
0.0	2.8	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.6	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:1902444	riboflavin binding(GO:1902444)
0.0	1.4	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	3.4	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	0.1	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.1	GO:0000384	first spliceosomal transesterification activity(GO:0000384)
0.0	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.3	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.6	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	1.1	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.4	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	1.1	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.0	0.3	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0017161	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0	0.9	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.0	1.5	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.4	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	1.0	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.5	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.0	0.4	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.7	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.3	GO:0048156	tau protein binding(GO:0048156)
0.0	0.8	GO:0016859	peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0	0.0	GO:0031531	thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.3	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	1.0	GO:0016279	protein-lysine N-methyltransferase activity(GO:0016279)
0.0	5.1	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.0	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) pyrimidine ribonucleotide binding(GO:0032557) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0	2.4	GO:0008022	protein C-terminus binding(GO:0008022)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	3.7	GO:0017016	Ras GTPase binding(GO:0017016)
0.0	1.4	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.0	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.6	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.2	11.7	PID IL3 PATHWAY	IL3-mediated signaling events
0.2	5.6	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	7.9	PID RAS PATHWAY	Regulation of Ras family activation
0.1	7.3	PID INSULIN PATHWAY	Insulin Pathway
0.1	3.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	9.9	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	4.9	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	7.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	3.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	3.9	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	3.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	2.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.1	3.9	PID AURORA B PATHWAY	Aurora B signaling
0.1	5.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	3.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	2.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.9	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	2.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	0.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	1.4	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	1.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	2.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.7	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.6	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.7	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	2.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	2.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	1.3	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	3.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.9	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	1.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	1.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.2	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.4	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.5	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.5	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.6	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.3	PID ATM PATHWAY	ATM pathway
0.0	0.5	PID IL4 2PATHWAY	IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	14.6	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.4	15.3	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.3	4.7	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	6.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.2	3.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.2	4.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	2.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.2	2.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	5.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	2.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	4.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	2.0	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	2.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	2.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	3.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.5	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	3.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	2.0	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	2.0	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	3.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.7	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	4.0	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	1.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	3.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	2.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	1.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	1.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.0	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	2.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	1.0	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	1.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.4	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	4.2	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	2.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	2.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	1.0	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	0.6	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	4.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	3.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	2.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	4.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.9	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	2.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	8.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	2.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.8	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	1.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	1.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	2.0	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.3	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.6	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.9	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	4.9	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis

Results for FOXL1

Z-value: 1.71

Motif logo

Transcription factors associated with FOXL1

Activity-expression correlation:

Activity profile of FOXL1 motif

Sorted Z-values of FOXL1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXL1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: