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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for FUBP1

Z-value: 1.09

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Transcription factors associated with FUBP1

Gene Symbol Gene ID Gene Info
ENSG00000162613.12 far upstream element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FUBP1hg19_v2_chr1_-_78444776_78444800-0.145.1e-01Click!

Activity profile of FUBP1 motif

Sorted Z-values of FUBP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_33891362 6.02 ENST00000395833.3
LIM domain only 2 (rhombotin-like 1)
chr4_-_16900242 5.14 ENST00000502640.1
ENST00000506732.1
LIM domain binding 2
chr4_-_16900184 4.36 ENST00000515064.1
LIM domain binding 2
chr4_-_101439242 4.35 ENST00000296420.4
endomucin
chr4_-_16900217 4.27 ENST00000441778.2
LIM domain binding 2
chr4_-_16900410 4.23 ENST00000304523.5
LIM domain binding 2
chr1_+_84609944 4.19 ENST00000370685.3
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_101439148 3.49 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
endomucin
chr3_-_112127981 3.02 ENST00000486726.2
RP11-231E6.1
chr21_+_17791648 2.75 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
long intergenic non-protein coding RNA 478
chr21_+_17791838 2.57 ENST00000453910.1
long intergenic non-protein coding RNA 478
chr14_+_61654271 2.33 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
protein kinase C, eta
chr4_-_89152474 2.28 ENST00000515655.1
ATP-binding cassette, sub-family G (WHITE), member 2
chr3_-_149051444 2.25 ENST00000296059.2
transmembrane 4 L six family member 18
chr21_+_17792672 2.23 ENST00000602620.1
long intergenic non-protein coding RNA 478
chr5_+_139027877 2.23 ENST00000302517.3
CXXC finger protein 5
chr2_-_183291741 2.20 ENST00000351439.5
ENST00000409365.1
phosphodiesterase 1A, calmodulin-dependent
chr9_+_75766763 1.98 ENST00000456643.1
ENST00000415424.1
annexin A1
chr1_+_109102652 1.97 ENST00000370035.3
ENST00000405454.1
family with sequence similarity 102, member B
chr5_-_88178964 1.83 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
myocyte enhancer factor 2C
chr18_-_53255766 1.80 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
transcription factor 4
chr3_-_187454281 1.75 ENST00000232014.4
B-cell CLL/lymphoma 6
chr5_-_88179017 1.75 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
myocyte enhancer factor 2C
chr12_+_48513570 1.61 ENST00000551804.1
phosphofructokinase, muscle
chr2_+_33359687 1.58 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr2_+_33359646 1.56 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr9_+_82186682 1.53 ENST00000376552.2
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_-_46766577 1.41 ENST00000256689.5
solute carrier family 38, member 2
chr17_+_67498538 1.34 ENST00000589647.1
mitogen-activated protein kinase kinase 6
chr14_+_65878565 1.30 ENST00000556518.1
ENST00000557164.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr9_+_82186872 1.18 ENST00000376544.3
ENST00000376520.4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_+_111473108 1.17 ENST00000304987.3
salt-inducible kinase 2
chr19_-_55453077 1.09 ENST00000328092.5
ENST00000590030.1
NLR family, pyrin domain containing 7
chr12_+_10365404 1.06 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr6_-_36725157 1.02 ENST00000393189.2
copine V
chr4_-_25865159 1.01 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr1_-_182360918 0.98 ENST00000339526.4
glutamate-ammonia ligase
chr2_+_201980827 0.94 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
CASP8 and FADD-like apoptosis regulator
chr10_-_65028817 0.94 ENST00000542921.1
jumonji domain containing 1C
chr22_-_29137771 0.93 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
checkpoint kinase 2
chr1_+_43766642 0.90 ENST00000372476.3
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr2_-_216300784 0.88 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr1_+_10290822 0.88 ENST00000377083.1
kinesin family member 1B
chr2_-_26205340 0.86 ENST00000264712.3
kinesin family member 3C
chr20_-_45981138 0.84 ENST00000446994.2
zinc finger, MYND-type containing 8
chr15_+_38276910 0.82 ENST00000558081.2
RP11-1008C21.1
chr12_+_56324933 0.79 ENST00000549629.1
ENST00000555218.1
diacylglycerol kinase, alpha 80kDa
chr21_-_38445011 0.79 ENST00000464265.1
ENST00000399102.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr14_+_69658480 0.77 ENST00000409949.1
ENST00000409242.1
ENST00000312994.5
ENST00000413191.1
exonuclease 3'-5' domain containing 2
chr1_-_244006528 0.77 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr1_+_205682497 0.75 ENST00000598338.1
AC119673.1
chr1_-_182360498 0.75 ENST00000417584.2
glutamate-ammonia ligase
chr1_+_78383813 0.73 ENST00000342754.5
nexilin (F actin binding protein)
chr11_-_66964638 0.73 ENST00000444002.2
AP001885.1
chr4_-_152149033 0.70 ENST00000514152.1
SH3 domain containing 19
chr15_-_55657428 0.69 ENST00000568543.1
cell cycle progression 1
chr8_-_120685608 0.69 ENST00000427067.2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr15_-_34628951 0.68 ENST00000397707.2
ENST00000560611.1
solute carrier family 12 (potassium/chloride transporter), member 6
chr4_+_170581213 0.66 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr7_-_15601595 0.65 ENST00000342526.3
alkylglycerol monooxygenase
chr18_+_7754957 0.65 ENST00000400053.4
protein tyrosine phosphatase, receptor type, M
chr19_-_55677999 0.62 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
dynein, axonemal, assembly factor 3
chrX_+_49644470 0.60 ENST00000508866.2
ubiquitin specific peptidase 27, X-linked
chr10_+_101542462 0.60 ENST00000370449.4
ENST00000370434.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr15_+_49170083 0.59 ENST00000530028.2
EP300 interacting inhibitor of differentiation 1
chr2_-_65593784 0.57 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr2_+_27435734 0.53 ENST00000419744.1
all-trans retinoic acid-induced differentiation factor
chr19_+_48969094 0.53 ENST00000595676.1
Uncharacterized protein
chr12_+_56324756 0.52 ENST00000331886.5
ENST00000555090.1
diacylglycerol kinase, alpha 80kDa
chr5_+_140027355 0.50 ENST00000417647.2
ENST00000507593.1
ENST00000508301.1
IK cytokine, down-regulator of HLA II
chr21_-_38445297 0.47 ENST00000430792.1
ENST00000399103.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr12_-_91576561 0.46 ENST00000547568.2
ENST00000552962.1
decorin
chr19_+_13134772 0.44 ENST00000587760.1
ENST00000585575.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_11546093 0.41 ENST00000591462.1
protein kinase C substrate 80K-H
chr6_+_119215308 0.41 ENST00000229595.5
anti-silencing function 1A histone chaperone
chr16_+_2205755 0.41 ENST00000326181.6
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
chr7_+_56131917 0.41 ENST00000434526.2
ENST00000275607.9
ENST00000395435.2
ENST00000413952.2
ENST00000342190.6
ENST00000437307.2
ENST00000413756.1
ENST00000451338.1
sulfatase modifying factor 2
chr2_+_162087577 0.38 ENST00000439442.1
TRAF family member-associated NFKB activator
chr14_+_89060739 0.37 ENST00000318308.6
zinc finger CCCH-type containing 14
chr2_+_181845843 0.36 ENST00000602710.1
ubiquitin-conjugating enzyme E2E 3
chr13_-_26795840 0.35 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
ring finger protein (C3H2C3 type) 6
chr1_+_41157361 0.33 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
nuclear transcription factor Y, gamma
chr1_-_44818599 0.32 ENST00000537474.1
ERI1 exoribonuclease family member 3
chr10_-_56561022 0.31 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
protocadherin-related 15
chr12_+_12870055 0.30 ENST00000228872.4
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr14_+_75761099 0.30 ENST00000561000.1
ENST00000558575.1
RP11-293M10.5
chr10_-_70092671 0.29 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
phenazine biosynthesis-like protein domain containing
chr11_+_120207787 0.29 ENST00000397843.2
ENST00000356641.3
Rho guanine nucleotide exchange factor (GEF) 12
chr2_+_177015950 0.28 ENST00000306324.3
homeobox D4
chr1_-_45140227 0.26 ENST00000372237.3
transmembrane protein 53
chrX_+_22056165 0.25 ENST00000535894.1
phosphate regulating endopeptidase homolog, X-linked
chr7_-_22234381 0.25 ENST00000458533.1
Rap guanine nucleotide exchange factor (GEF) 5
chr3_+_19988566 0.24 ENST00000273047.4
RAB5A, member RAS oncogene family
chr8_+_40018977 0.24 ENST00000520487.1
RP11-470M17.2
chr1_-_45140074 0.24 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
transmembrane protein 53
chr4_-_84205905 0.24 ENST00000311461.7
ENST00000311469.4
ENST00000439031.2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
chr1_-_216978709 0.24 ENST00000360012.3
estrogen-related receptor gamma
chr18_-_60986613 0.24 ENST00000444484.1
B-cell CLL/lymphoma 2
chr10_+_74653330 0.23 ENST00000334011.5
oncoprotein induced transcript 3
chr1_-_11741155 0.23 ENST00000445656.1
ENST00000376669.5
ENST00000456915.1
ENST00000376692.4
MAD2 mitotic arrest deficient-like 2 (yeast)
chr18_-_60985914 0.23 ENST00000589955.1
B-cell CLL/lymphoma 2
chr3_+_130279178 0.23 ENST00000358511.6
ENST00000453409.2
collagen, type VI, alpha 6
chr12_+_16109519 0.22 ENST00000526530.1
deoxyribose-phosphate aldolase (putative)
chr5_+_180682720 0.20 ENST00000599439.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chrX_+_102585124 0.19 ENST00000332431.4
ENST00000372666.1
transcription elongation factor A (SII)-like 7
chrX_+_52235228 0.19 ENST00000518075.1
X antigen family, member 1B
chr18_+_18943554 0.19 ENST00000580732.2
growth regulation by estrogen in breast cancer-like
chr10_-_56560939 0.18 ENST00000373955.1
protocadherin-related 15
chr7_+_74508372 0.16 ENST00000356115.5
ENST00000430511.2
ENST00000312575.7
GTF2I repeat domain containing 2B
chr19_+_19303008 0.15 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
regulatory factor X-associated ankyrin-containing protein
chr15_+_49462434 0.15 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
galactokinase 2
chr15_+_80364901 0.15 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
zinc finger, AN1-type domain 6
chr17_-_42298331 0.15 ENST00000343638.5
upstream binding transcription factor, RNA polymerase I
chr17_-_76713100 0.15 ENST00000585509.1
cytohesin 1
chr15_+_49462397 0.13 ENST00000396509.2
galactokinase 2
chr1_+_202317855 0.13 ENST00000356764.2
protein phosphatase 1, regulatory subunit 12B
chr6_+_167525277 0.12 ENST00000400926.2
chemokine (C-C motif) receptor 6
chr12_-_91451758 0.11 ENST00000266719.3
keratocan
chr17_-_15469590 0.11 ENST00000312127.2
CMT duplicated region transcript 1; Uncharacterized protein
chr19_+_18682661 0.11 ENST00000596273.1
ENST00000442744.2
ENST00000595683.1
ENST00000599256.1
ENST00000595158.1
ENST00000598780.1
ubiquitin A-52 residue ribosomal protein fusion product 1
chr19_-_45996465 0.10 ENST00000430715.2
reticulon 2
chr19_+_1438351 0.10 ENST00000233609.4
ribosomal protein S15
chr10_+_51187938 0.10 ENST00000311663.5
family with sequence similarity 21, member D
chr3_+_148545586 0.10 ENST00000282957.4
ENST00000468341.1
carboxypeptidase B1 (tissue)
chr2_-_169746878 0.09 ENST00000282074.2
SPC25, NDC80 kinetochore complex component
chr17_-_41738931 0.09 ENST00000329168.3
ENST00000549132.1
mesenchyme homeobox 1
chr12_+_111374375 0.09 ENST00000553177.1
ENST00000548368.1
ENST00000331096.2
ENST00000547607.1
RP1-46F2.2
chr15_+_52155001 0.08 ENST00000544199.1
tropomodulin 3 (ubiquitous)
chr17_-_41739283 0.08 ENST00000393661.2
ENST00000318579.4
mesenchyme homeobox 1
chr7_-_74267836 0.08 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
GTF2I repeat domain containing 2
chrX_+_12924732 0.08 ENST00000218032.6
ENST00000311912.5
toll-like receptor 8
chrX_+_119737806 0.08 ENST00000371317.5
malignant T cell amplified sequence 1
chr9_+_42671887 0.07 ENST00000456520.1
ENST00000377391.3
COBW domain containing 7
chr11_+_98891797 0.07 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
contactin 5
chr11_-_67169253 0.07 ENST00000527663.1
ENST00000312989.7
protein phosphatase 1, catalytic subunit, alpha isozyme
chr1_+_228870824 0.06 ENST00000366691.3
ras homolog family member U
chr16_+_28565230 0.06 ENST00000317058.3
coiled-coil domain containing 101
chr3_-_169587621 0.05 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
leucine rich repeat containing 31
chr1_+_89149905 0.05 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
protein kinase N2
chr10_+_79793518 0.05 ENST00000440692.1
ENST00000435275.1
ENST00000372360.3
ENST00000360830.4
ribosomal protein S24
chr2_+_113033164 0.04 ENST00000409871.1
ENST00000343936.4
zinc finger CCCH-type containing 6
chr6_-_111888474 0.04 ENST00000368735.1
TRAF3 interacting protein 2
chr9_-_110251836 0.04 ENST00000374672.4
Kruppel-like factor 4 (gut)
chr11_-_107590383 0.03 ENST00000525934.1
ENST00000531293.1
sarcolipin
chr3_-_149510553 0.03 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr1_-_245134273 0.02 ENST00000607453.1
Uncharacterized protein
chr5_+_137225158 0.02 ENST00000290431.5
polycystic kidney disease 2-like 2
chr11_+_60681346 0.02 ENST00000227525.3
transmembrane protein 109
chr7_+_54609995 0.02 ENST00000302287.3
ENST00000407838.3
V-set and transmembrane domain containing 2A
chr7_+_139529040 0.01 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
thromboxane A synthase 1 (platelet)
chr8_+_94929969 0.01 ENST00000517764.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr13_+_49551020 0.00 ENST00000541916.1
fibronectin type III domain containing 3A
chr3_+_57875738 0.00 ENST00000417128.1
ENST00000438794.1
sarcolemma associated protein
chr1_+_209602771 0.00 ENST00000440276.1
MIR205 host gene (non-protein coding)

Network of associatons between targets according to the STRING database.

First level regulatory network of FUBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.7 2.0 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.6 4.2 GO:0097338 response to clozapine(GO:0097338)
0.6 1.8 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.6 18.3 GO:0010669 epithelial structure maintenance(GO:0010669)
0.5 1.6 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.4 1.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 1.3 GO:0036071 N-glycan fucosylation(GO:0036071)
0.4 1.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 3.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 0.9 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3 0.9 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 6.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.2 2.3 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2 0.9 GO:1904647 response to rotenone(GO:1904647)
0.2 0.6 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.2 2.3 GO:0042908 xenobiotic transport(GO:0042908)
0.2 1.4 GO:0032328 alanine transport(GO:0032328)
0.1 0.8 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.7 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 2.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.5 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.9 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.1 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.5 GO:0050957 equilibrioception(GO:0050957)
0.0 1.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 2.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:1902746 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.5 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.8 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 1.0 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0051036 regulation of endosome size(GO:0051036)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.6 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.9 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 1.2 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500) negative regulation of muscle hyperplasia(GO:0014740) positive regulation of core promoter binding(GO:1904798)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.0 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 2.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.2 4.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 3.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.7 GO:0097386 glial cell projection(GO:0097386)
0.1 0.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 25.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.9 GO:0097342 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.8 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 18.0 GO:0030274 LIM domain binding(GO:0030274)
0.6 3.1 GO:0050436 microfibril binding(GO:0050436)
0.5 2.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.4 1.3 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.4 1.7 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 2.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 2.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 1.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 2.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 4.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 3.6 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.6 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.7 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 6.0 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.7 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 1.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 1.1 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.7 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 3.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.6 GO:0016504 peptidase activator activity(GO:0016504)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 4.2 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 4.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 2.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 7.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 3.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 3.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 5.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.9 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 2.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production