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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for GATA1_GATA4

Z-value: 0.73

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Transcription factors associated with GATA1_GATA4

Gene Symbol Gene ID Gene Info
GATA1
ENSG00000102145.9 GATA binding protein 1
GATA4
ENSG00000136574.13 GATA binding protein 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA1hg19_v2_chrX_+_48644962_486449830.252.3e-01Click!
GATA4hg19_v2_chr8_+_11534462_115344750.048.6e-01Click!

Activity profile of GATA1_GATA4 motif

Sorted Z-values of GATA1_GATA4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_159094194 1.34 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr10_-_99531709 1.06 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr10_+_28822636 1.00 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr1_+_25598989 0.99 ENST00000454452.2
RHD
Rh blood group, D antigen
chr7_+_100547156 0.98 ENST00000379458.4
MUC3A
Protein LOC100131514
chr2_+_109237717 0.84 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_189156721 0.78 ENST00000409927.1
ENST00000409805.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr1_+_25599018 0.77 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD
Rh blood group, D antigen
chr2_+_189156586 0.70 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr3_+_151986709 0.69 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr10_+_28822417 0.68 ENST00000428935.1
ENST00000420266.1
WAC
WW domain containing adaptor with coiled-coil
chr1_-_226187013 0.68 ENST00000272091.7
SDE2
SDE2 telomere maintenance homolog (S. pombe)
chr22_-_43042955 0.67 ENST00000402438.1
CYB5R3
cytochrome b5 reductase 3
chr1_+_25598872 0.63 ENST00000328664.4
RHD
Rh blood group, D antigen
chr17_-_79817091 0.62 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr12_+_109785708 0.62 ENST00000310903.5
MYO1H
myosin IH
chr19_-_55669093 0.60 ENST00000344887.5
TNNI3
troponin I type 3 (cardiac)
chr14_+_102276192 0.59 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr2_+_3642545 0.59 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
COLEC11
collectin sub-family member 11
chr6_+_31674639 0.58 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
LY6G6F
MEGT1
lymphocyte antigen 6 complex, locus G6F
HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr20_+_43935474 0.57 ENST00000372743.1
ENST00000372741.3
ENST00000343694.3
RBPJL
recombination signal binding protein for immunoglobulin kappa J region-like
chr2_+_242289502 0.54 ENST00000451310.1
SEPT2
septin 2
chr2_-_188312971 0.52 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr2_+_201994569 0.51 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr8_-_93107696 0.48 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_138539627 0.48 ENST00000527246.2
PBOV1
prostate and breast cancer overexpressed 1
chr12_+_9102632 0.47 ENST00000539240.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr11_+_128563652 0.47 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr12_+_9144626 0.45 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chrX_+_135279179 0.45 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr10_+_118305435 0.44 ENST00000369221.2
PNLIP
pancreatic lipase
chr12_-_114841703 0.44 ENST00000526441.1
TBX5
T-box 5
chr15_-_34610962 0.43 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr1_-_243326612 0.42 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr4_+_169552748 0.42 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr9_+_118950325 0.41 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr14_+_85996507 0.41 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr11_-_116708302 0.39 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1
apolipoprotein A-I
chr22_-_43042968 0.39 ENST00000407623.3
ENST00000396303.3
ENST00000438270.1
CYB5R3
cytochrome b5 reductase 3
chr7_+_128379346 0.38 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr2_+_201994042 0.37 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr5_-_20575959 0.37 ENST00000507958.1
CDH18
cadherin 18, type 2
chr10_+_52152766 0.37 ENST00000596442.1
AC069547.2
Uncharacterized protein
chr3_-_194188956 0.37 ENST00000256031.4
ENST00000446356.1
ATP13A3
ATPase type 13A3
chr5_+_135496675 0.37 ENST00000507637.1
SMAD5
SMAD family member 5
chr12_-_6233828 0.37 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chrX_+_135278908 0.36 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr4_+_74702214 0.36 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr22_+_35462129 0.36 ENST00000404699.2
ENST00000308700.6
ISX
intestine-specific homeobox
chr5_+_67584174 0.36 ENST00000320694.8
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr3_+_72200408 0.35 ENST00000473713.1
LINC00870
long intergenic non-protein coding RNA 870
chr8_+_70404996 0.35 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr11_+_128563948 0.34 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr5_+_125695805 0.34 ENST00000513040.1
GRAMD3
GRAM domain containing 3
chr22_-_31688381 0.33 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr14_+_60975644 0.33 ENST00000327720.5
SIX6
SIX homeobox 6
chr8_-_6420565 0.33 ENST00000338312.6
ANGPT2
angiopoietin 2
chr20_+_57226841 0.33 ENST00000358029.4
ENST00000361830.3
STX16
syntaxin 16
chr8_-_93107443 0.32 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_169418255 0.32 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr1_-_112046110 0.31 ENST00000369716.4
ADORA3
adenosine A3 receptor
chr11_-_47374246 0.31 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3
myosin binding protein C, cardiac
chr10_+_118350522 0.31 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr16_+_71560154 0.31 ENST00000539698.3
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr16_+_71560023 0.31 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr16_+_70680439 0.31 ENST00000288098.2
IL34
interleukin 34
chrX_+_48380205 0.30 ENST00000446158.1
ENST00000414061.1
EBP
emopamil binding protein (sterol isomerase)
chr1_+_199996733 0.30 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr17_+_4675175 0.30 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr1_-_163172625 0.30 ENST00000527988.1
ENST00000531476.1
ENST00000530507.1
RGS5
regulator of G-protein signaling 5
chr8_-_6420759 0.30 ENST00000523120.1
ANGPT2
angiopoietin 2
chr5_-_135290705 0.30 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr2_+_189156389 0.30 ENST00000409843.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr17_-_38938786 0.29 ENST00000301656.3
KRT27
keratin 27
chr6_+_167704798 0.28 ENST00000230256.3
UNC93A
unc-93 homolog A (C. elegans)
chr5_-_19988339 0.27 ENST00000382275.1
CDH18
cadherin 18, type 2
chr13_+_111855414 0.27 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr8_+_21823726 0.27 ENST00000433566.4
XPO7
exportin 7
chr19_+_10397621 0.27 ENST00000380770.3
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr9_-_13175823 0.26 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr1_-_112046289 0.26 ENST00000241356.4
ADORA3
adenosine A3 receptor
chr7_+_155090271 0.26 ENST00000476756.1
INSIG1
insulin induced gene 1
chr10_+_118350468 0.26 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr6_-_52441713 0.26 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr14_-_94421923 0.26 ENST00000555507.1
ASB2
ankyrin repeat and SOCS box containing 2
chr6_+_167704838 0.26 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chr14_-_24584138 0.26 ENST00000558280.1
ENST00000561028.1
NRL
neural retina leucine zipper
chr1_-_214638146 0.25 ENST00000543945.1
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr13_+_28527647 0.25 ENST00000567234.1
LINC00543
long intergenic non-protein coding RNA 543
chr2_+_109204743 0.25 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr11_-_105892937 0.25 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr4_-_70826725 0.25 ENST00000353151.3
CSN2
casein beta
chr12_-_30907862 0.25 ENST00000541765.1
ENST00000537108.1
CAPRIN2
caprin family member 2
chr19_+_10397648 0.25 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr14_-_31676964 0.25 ENST00000553700.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr18_-_77276057 0.24 ENST00000597412.1
AC018445.1
Uncharacterized protein
chr8_+_42873548 0.24 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr8_-_93107827 0.24 ENST00000520724.1
ENST00000518844.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_-_43513187 0.24 ENST00000540029.1
ENST00000441366.2
EPB42
erythrocyte membrane protein band 4.2
chr8_-_143961236 0.24 ENST00000377675.3
ENST00000517471.1
ENST00000292427.4
CYP11B1
cytochrome P450, family 11, subfamily B, polypeptide 1
chr15_+_77287426 0.24 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr21_-_43786634 0.24 ENST00000291527.2
TFF1
trefoil factor 1
chr4_+_78432907 0.24 ENST00000286758.4
CXCL13
chemokine (C-X-C motif) ligand 13
chr12_+_75874984 0.24 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr11_+_64053005 0.24 ENST00000538032.1
GPR137
G protein-coupled receptor 137
chr6_-_131277510 0.24 ENST00000525193.1
ENST00000527659.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr14_-_50559361 0.23 ENST00000305273.1
C14orf183
chromosome 14 open reading frame 183
chr12_-_9102549 0.23 ENST00000000412.3
M6PR
mannose-6-phosphate receptor (cation dependent)
chr1_-_25747283 0.23 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
RHCE
Rh blood group, CcEe antigens
chr2_+_160590469 0.23 ENST00000409591.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr10_+_180405 0.23 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
ZMYND11
zinc finger, MYND-type containing 11
chr1_-_159880159 0.23 ENST00000599780.1
AL590560.1
HCG1995379; Uncharacterized protein
chr12_+_74931551 0.22 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr4_+_41361616 0.22 ENST00000513024.1
LIMCH1
LIM and calponin homology domains 1
chr12_-_120765565 0.22 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr14_+_64680854 0.22 ENST00000458046.2
SYNE2
spectrin repeat containing, nuclear envelope 2
chr19_+_36132631 0.22 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr6_-_86099898 0.22 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr6_+_132891461 0.22 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr12_+_15699286 0.22 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr1_+_109255279 0.22 ENST00000370017.3
FNDC7
fibronectin type III domain containing 7
chr9_+_133978190 0.21 ENST00000372312.3
AIF1L
allograft inflammatory factor 1-like
chr14_-_88459182 0.21 ENST00000544807.2
GALC
galactosylceramidase
chr12_+_79439405 0.20 ENST00000552744.1
SYT1
synaptotagmin I
chr1_+_109256067 0.20 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr1_+_66797687 0.20 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chrY_-_13524717 0.20 ENST00000331172.6
SLC9B1P1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 pseudogene 1
chr8_+_124194875 0.20 ENST00000522648.1
ENST00000276699.6
FAM83A
family with sequence similarity 83, member A
chr2_+_201981527 0.20 ENST00000441224.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr15_-_64126084 0.20 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr3_+_172468505 0.20 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
ECT2
epithelial cell transforming sequence 2 oncogene
chr8_+_27629459 0.20 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr9_-_13279406 0.19 ENST00000546205.1
MPDZ
multiple PDZ domain protein
chr5_+_147443534 0.19 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5
serine peptidase inhibitor, Kazal type 5
chr16_+_81272287 0.19 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr3_+_111393501 0.19 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr7_+_5919458 0.19 ENST00000416608.1
OCM
oncomodulin
chr3_-_58196688 0.19 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr11_-_59612969 0.19 ENST00000541311.1
ENST00000257248.2
GIF
gastric intrinsic factor (vitamin B synthesis)
chr12_-_109221160 0.19 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr10_-_104597286 0.19 ENST00000369887.3
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr12_-_122879969 0.19 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr15_-_34628951 0.19 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr1_-_153113927 0.19 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr1_-_179545059 0.19 ENST00000367615.4
ENST00000367616.4
NPHS2
nephrosis 2, idiopathic, steroid-resistant (podocin)
chr12_-_67197760 0.19 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chrX_+_44703249 0.18 ENST00000339042.4
DUSP21
dual specificity phosphatase 21
chr9_+_140125385 0.18 ENST00000361134.2
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr8_-_103876383 0.18 ENST00000347770.4
AZIN1
antizyme inhibitor 1
chr1_+_244214577 0.18 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr1_+_50574585 0.18 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr1_+_61330931 0.18 ENST00000371191.1
NFIA
nuclear factor I/A
chr1_+_22328144 0.18 ENST00000290122.3
ENST00000374663.1
CELA3A
chymotrypsin-like elastase family, member 3A
chr15_+_42066740 0.18 ENST00000514566.1
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr11_+_64052944 0.18 ENST00000535675.1
ENST00000543383.1
GPR137
G protein-coupled receptor 137
chr22_+_22550113 0.18 ENST00000390285.3
IGLV6-57
immunoglobulin lambda variable 6-57
chr6_+_143929307 0.18 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr12_-_71031185 0.18 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chrX_+_108779870 0.18 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr15_-_58306295 0.17 ENST00000559517.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr12_+_56477093 0.17 ENST00000549672.1
ENST00000415288.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr15_-_52861323 0.17 ENST00000569723.1
ENST00000249822.4
ENST00000567669.1
ENST00000569281.2
ENST00000563566.1
ENST00000567830.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr4_-_104640973 0.17 ENST00000304883.2
TACR3
tachykinin receptor 3
chr3_+_157828152 0.17 ENST00000476899.1
RSRC1
arginine/serine-rich coiled-coil 1
chr12_-_52995291 0.17 ENST00000293745.2
ENST00000354310.4
KRT72
keratin 72
chr10_+_31610064 0.17 ENST00000446923.2
ENST00000559476.1
ZEB1
zinc finger E-box binding homeobox 1
chr4_+_123073464 0.17 ENST00000264501.4
KIAA1109
KIAA1109
chr20_-_4990931 0.17 ENST00000379333.1
SLC23A2
solute carrier family 23 (ascorbic acid transporter), member 2
chr21_-_35016231 0.16 ENST00000438788.1
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr1_+_114472481 0.16 ENST00000369555.2
HIPK1
homeodomain interacting protein kinase 1
chr5_+_131409476 0.16 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr7_-_107880508 0.16 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr10_+_94594351 0.16 ENST00000371552.4
EXOC6
exocyst complex component 6
chr3_-_119379427 0.16 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
POPDC2
popeye domain containing 2
chr22_-_20231207 0.16 ENST00000425986.1
RTN4R
reticulon 4 receptor
chr18_-_3219847 0.16 ENST00000261606.7
MYOM1
myomesin 1
chr8_+_29605825 0.16 ENST00000522158.1
AC145110.1
AC145110.1
chr2_-_219850277 0.16 ENST00000295727.1
FEV
FEV (ETS oncogene family)
chr9_+_132099158 0.15 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr6_-_29395509 0.15 ENST00000377147.2
OR11A1
olfactory receptor, family 11, subfamily A, member 1
chr1_-_154150651 0.15 ENST00000302206.5
TPM3
tropomyosin 3
chr13_+_32313658 0.15 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr6_+_41010293 0.15 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
TSPO2
translocator protein 2
chr11_+_64052294 0.15 ENST00000536667.1
GPR137
G protein-coupled receptor 137
chr4_-_103266355 0.15 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr5_+_173316341 0.15 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr1_-_24469602 0.15 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr9_-_75567962 0.15 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chrX_-_117119243 0.15 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr6_-_32498046 0.15 ENST00000374975.3
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr16_+_215965 0.15 ENST00000356815.3
HBM
hemoglobin, mu
chr7_-_121944491 0.15 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr5_+_140797296 0.15 ENST00000398594.2
PCDHGB7
protocadherin gamma subfamily B, 7
chr4_-_120243545 0.15 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr1_-_235098935 0.15 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr6_-_29396243 0.15 ENST00000377148.1
OR11A1
olfactory receptor, family 11, subfamily A, member 1
chr1_+_87595497 0.15 ENST00000471417.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr2_+_162480918 0.15 ENST00000272716.5
ENST00000446997.1
SLC4A10
solute carrier family 4, sodium bicarbonate transporter, member 10
chr5_+_121647764 0.14 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
SNCAIP
synuclein, alpha interacting protein
chr5_+_121647924 0.14 ENST00000414317.2
SNCAIP
synuclein, alpha interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA1_GATA4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.3 1.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2 0.9 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.4 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.7 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.1 1.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.6 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.4 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 2.6 GO:0015695 organic cation transport(GO:0015695)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.2 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.2 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.6 GO:0006477 protein sulfation(GO:0006477)
0.1 0.3 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.4 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.2 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.3 GO:1902267 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.1 0.4 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 1.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.4 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.2 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.5 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.0 0.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.5 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:1903465 vacuolar phosphate transport(GO:0007037) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.1 GO:0046100 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 1.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0044241 lipid digestion(GO:0044241)
0.0 0.2 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:1990822 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.0 0.2 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0032341 aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342) cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.1 GO:0070091 response to selenium ion(GO:0010269) glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0021740 aggressive behavior(GO:0002118) trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.1 GO:1903027 regulation of opsonization(GO:1903027)
0.0 0.3 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.2 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 1.7 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.2 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0098707 ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0019374 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.8 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 1.0 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.0 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.5 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 0.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.2 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.6 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0036028 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.8 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.0 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.4 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.4 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 1.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.6 GO:0030172 troponin C binding(GO:0030172)
0.1 2.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.2 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.2 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.2 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 1.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 1.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0042979 ornithine decarboxylase activator activity(GO:0042978) ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0043208 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.5 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction