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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for GATA2

Z-value: 0.87

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Transcription factors associated with GATA2

Gene Symbol Gene ID Gene Info
GATA2
ENSG00000179348.7 GATA binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA2hg19_v2_chr3_-_128206759_128206781-0.174.3e-01Click!

Activity profile of GATA2 motif

Sorted Z-values of GATA2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_2029019 2.48 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr13_+_32838801 1.96 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr1_+_84630053 1.84 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_186733363 1.84 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr1_+_78511586 1.82 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr9_-_14180778 1.82 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr11_+_33563821 1.81 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr12_-_10959892 1.57 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr1_+_114522049 1.51 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr20_+_34802295 1.50 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr9_-_47314222 1.49 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
AL953854.2
chr6_+_132455118 1.36 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr4_-_70626314 1.23 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr1_+_84630645 1.22 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_+_2157655 1.21 ENST00000452193.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_-_38671098 1.20 ENST00000356264.2
AMPH
amphiphysin
chr4_+_126237554 1.18 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chr7_-_38670957 1.16 ENST00000325590.5
ENST00000428293.2
AMPH
amphiphysin
chr5_-_100238956 1.12 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr9_-_13175823 1.10 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr10_-_116286563 1.09 ENST00000369253.2
ABLIM1
actin binding LIM protein 1
chr12_-_9268707 1.09 ENST00000318602.7
A2M
alpha-2-macroglobulin
chr3_+_141105235 1.08 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr8_-_93029865 1.05 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_+_8096631 1.04 ENST00000379328.3
GATA3
GATA binding protein 3
chr7_-_120498357 1.03 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr4_-_90758118 1.03 ENST00000420646.2
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr10_-_116444371 1.01 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr9_-_13165457 0.97 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr12_+_19358228 0.94 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr5_+_140579162 0.94 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chr17_+_32597232 0.93 ENST00000378569.2
ENST00000200307.4
ENST00000394627.1
ENST00000394630.3
CCL7
chemokine (C-C motif) ligand 7
chr1_-_47131521 0.91 ENST00000542495.1
ENST00000532925.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr10_+_35484053 0.90 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
CREM
cAMP responsive element modulator
chr20_+_42544782 0.90 ENST00000423191.2
ENST00000372999.1
TOX2
TOX high mobility group box family member 2
chr12_+_79258547 0.89 ENST00000457153.2
SYT1
synaptotagmin I
chr1_-_20503917 0.88 ENST00000429261.2
PLA2G2C
phospholipase A2, group IIC
chr12_-_91546926 0.86 ENST00000550758.1
DCN
decorin
chr10_+_112631547 0.85 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr12_+_9144626 0.85 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr20_+_42574317 0.83 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr2_+_89890533 0.80 ENST00000429992.2
IGKV2D-40
immunoglobulin kappa variable 2D-40
chr12_+_79439405 0.80 ENST00000552744.1
SYT1
synaptotagmin I
chr16_+_55542910 0.78 ENST00000262134.5
LPCAT2
lysophosphatidylcholine acyltransferase 2
chr10_+_101542462 0.78 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr8_-_99129338 0.78 ENST00000520507.1
HRSP12
heat-responsive protein 12
chr17_+_40913264 0.77 ENST00000587142.1
ENST00000588576.1
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr12_-_7848364 0.76 ENST00000329913.3
GDF3
growth differentiation factor 3
chr16_+_56995762 0.75 ENST00000200676.3
ENST00000379780.2
CETP
cholesteryl ester transfer protein, plasma
chr4_-_90757364 0.74 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr7_-_86974767 0.74 ENST00000610086.1
TP53TG1
TP53 target 1 (non-protein coding)
chr6_+_7727030 0.74 ENST00000283147.6
BMP6
bone morphogenetic protein 6
chr3_-_148804275 0.71 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF
helicase-like transcription factor
chr5_-_88179017 0.71 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
MEF2C
myocyte enhancer factor 2C
chr7_+_94023873 0.70 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr7_-_86974785 0.70 ENST00000432193.1
ENST00000421293.1
ENST00000542586.1
ENST00000359941.5
ENST00000416560.1
TP53TG1
TP53 target 1 (non-protein coding)
chr11_-_66115032 0.69 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr9_-_79307096 0.69 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2
prune homolog 2 (Drosophila)
chr2_+_201994569 0.68 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_+_141043050 0.68 ENST00000509842.1
ZBTB38
zinc finger and BTB domain containing 38
chr17_+_15848231 0.67 ENST00000304222.2
ADORA2B
adenosine A2b receptor
chr11_-_121986923 0.66 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr5_+_148737562 0.65 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr14_-_90085458 0.65 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr14_+_61995722 0.65 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chrX_-_77395186 0.64 ENST00000341864.5
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr18_+_3466248 0.64 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr12_+_48513009 0.64 ENST00000359794.5
ENST00000551339.1
ENST00000395233.2
ENST00000548345.1
PFKM
phosphofructokinase, muscle
chr2_-_197041193 0.63 ENST00000409228.1
STK17B
serine/threonine kinase 17b
chr15_+_42867857 0.62 ENST00000290607.7
STARD9
StAR-related lipid transfer (START) domain containing 9
chr12_-_12491608 0.62 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr3_-_168865522 0.61 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr3_-_149095652 0.61 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr9_+_21409146 0.61 ENST00000380205.1
IFNA8
interferon, alpha 8
chr12_-_71533055 0.60 ENST00000552128.1
TSPAN8
tetraspanin 8
chr4_+_74735102 0.60 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr12_-_95009837 0.59 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chrX_+_149531524 0.59 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr17_+_4402133 0.59 ENST00000329078.3
SPNS2
spinster homolog 2 (Drosophila)
chr11_-_89224638 0.59 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr6_+_32944119 0.56 ENST00000606059.1
BRD2
bromodomain containing 2
chr6_+_17393888 0.55 ENST00000493172.1
ENST00000465994.1
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr11_+_31531291 0.54 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr12_-_31158902 0.53 ENST00000544329.1
ENST00000418254.2
ENST00000222396.5
RP11-551L14.4
RP11-551L14.4
chr5_-_88119580 0.53 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr13_+_103451399 0.53 ENST00000257336.1
ENST00000448849.2
BIVM
basic, immunoglobulin-like variable motif containing
chr2_-_235405168 0.53 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr13_-_103451307 0.52 ENST00000376004.4
KDELC1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr18_-_53303123 0.52 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr9_+_72002837 0.52 ENST00000377216.3
FAM189A2
family with sequence similarity 189, member A2
chr13_+_103451548 0.51 ENST00000419638.1
BIVM
basic, immunoglobulin-like variable motif containing
chr12_+_29376673 0.51 ENST00000547116.1
FAR2
fatty acyl CoA reductase 2
chr4_-_74904398 0.51 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr6_-_80657292 0.50 ENST00000369816.4
ELOVL4
ELOVL fatty acid elongase 4
chr12_+_29376592 0.50 ENST00000182377.4
FAR2
fatty acyl CoA reductase 2
chr18_-_29340827 0.50 ENST00000269205.5
SLC25A52
solute carrier family 25, member 52
chr13_-_114843416 0.49 ENST00000389544.4
RASA3
RAS p21 protein activator 3
chr9_+_90112117 0.49 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr1_+_90098606 0.49 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr14_-_106453155 0.49 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr7_+_77167343 0.49 ENST00000433369.2
ENST00000415482.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr9_+_116267536 0.48 ENST00000374136.1
RGS3
regulator of G-protein signaling 3
chr4_-_152149033 0.48 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr18_+_3448455 0.48 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr9_+_5450503 0.48 ENST00000381573.4
ENST00000381577.3
CD274
CD274 molecule
chr12_-_9913489 0.47 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr8_-_93107827 0.46 ENST00000520724.1
ENST00000518844.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_76155618 0.46 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr18_-_21891460 0.46 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr19_-_11494975 0.46 ENST00000222139.6
ENST00000592375.2
EPOR
erythropoietin receptor
chr1_+_78383813 0.46 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr3_-_58196688 0.46 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr21_-_31869451 0.45 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr7_+_16793160 0.44 ENST00000262067.4
TSPAN13
tetraspanin 13
chr10_+_5135981 0.44 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr1_+_84630367 0.44 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr20_-_46415297 0.44 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr15_+_45003675 0.44 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr11_+_34654011 0.44 ENST00000531794.1
EHF
ets homologous factor
chr3_+_194406603 0.44 ENST00000329759.4
FAM43A
family with sequence similarity 43, member A
chr8_+_74903580 0.44 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr1_-_211752073 0.43 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr1_-_54303949 0.43 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chr21_-_40033618 0.43 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr15_+_63569785 0.43 ENST00000380343.4
ENST00000560353.1
APH1B
APH1B gamma secretase subunit
chr9_+_12693336 0.42 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr4_-_159956333 0.42 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr15_-_52587945 0.41 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C
myosin VC
chr16_-_15187865 0.41 ENST00000327307.7
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr7_-_120497178 0.41 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr8_-_17941575 0.41 ENST00000417108.2
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr5_-_9630463 0.41 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr3_-_182817367 0.41 ENST00000265594.4
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr4_+_156680518 0.41 ENST00000513437.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr2_-_74667612 0.41 ENST00000305557.5
ENST00000233330.6
RTKN
rhotekin
chr1_+_159409512 0.40 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr15_+_83776324 0.40 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
TM6SF1
transmembrane 6 superfamily member 1
chr10_-_72141330 0.40 ENST00000395011.1
ENST00000395010.1
LRRC20
leucine rich repeat containing 20
chr6_-_167571817 0.40 ENST00000366834.1
GPR31
G protein-coupled receptor 31
chr11_-_76155700 0.39 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chrX_-_67653614 0.39 ENST00000355520.5
OPHN1
oligophrenin 1
chr19_+_1041212 0.39 ENST00000433129.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr22_-_32860427 0.39 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr3_-_49170405 0.38 ENST00000305544.4
ENST00000494831.1
LAMB2
laminin, beta 2 (laminin S)
chr1_-_153066998 0.38 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr5_+_74011328 0.38 ENST00000513336.1
HEXB
hexosaminidase B (beta polypeptide)
chr15_-_34659349 0.38 ENST00000314891.6
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr12_-_95510743 0.38 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr19_+_45971246 0.37 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr19_+_39904168 0.37 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr10_-_105677886 0.36 ENST00000224950.3
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr3_-_182817297 0.36 ENST00000539926.1
ENST00000476176.1
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr3_-_49170522 0.36 ENST00000418109.1
LAMB2
laminin, beta 2 (laminin S)
chr6_+_80816342 0.36 ENST00000369760.4
ENST00000356489.5
ENST00000320393.6
BCKDHB
branched chain keto acid dehydrogenase E1, beta polypeptide
chrX_-_74376108 0.36 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr15_-_23932437 0.36 ENST00000331837.4
NDN
necdin, melanoma antigen (MAGE) family member
chr7_+_139025875 0.36 ENST00000297534.6
C7orf55
chromosome 7 open reading frame 55
chr11_-_31531121 0.35 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr3_-_48754599 0.35 ENST00000413654.1
ENST00000454335.1
ENST00000440424.1
ENST00000449610.1
ENST00000443964.1
ENST00000417896.1
ENST00000413298.1
ENST00000449563.1
ENST00000443853.1
ENST00000437427.1
ENST00000446860.1
ENST00000412850.1
ENST00000424035.1
ENST00000340879.4
ENST00000431721.2
ENST00000434860.1
ENST00000328631.5
ENST00000432678.2
IP6K2
inositol hexakisphosphate kinase 2
chrX_-_77150911 0.35 ENST00000373336.3
MAGT1
magnesium transporter 1
chr2_-_99224915 0.35 ENST00000328709.3
ENST00000409997.1
COA5
cytochrome c oxidase assembly factor 5
chr19_+_18530146 0.35 ENST00000348495.6
ENST00000270061.7
SSBP4
single stranded DNA binding protein 4
chr2_-_89247338 0.35 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr14_-_51027838 0.35 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chrX_+_77154935 0.35 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr21_-_35016231 0.35 ENST00000438788.1
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr17_+_3323862 0.35 ENST00000291231.1
OR3A3
olfactory receptor, family 3, subfamily A, member 3
chr13_+_73632897 0.35 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr6_+_30951487 0.35 ENST00000486149.2
ENST00000376296.3
MUC21
mucin 21, cell surface associated
chr19_+_41509851 0.35 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr1_-_204116078 0.35 ENST00000367198.2
ENST00000452983.1
ETNK2
ethanolamine kinase 2
chr6_+_80816372 0.34 ENST00000545529.1
BCKDHB
branched chain keto acid dehydrogenase E1, beta polypeptide
chr7_+_65338312 0.34 ENST00000434382.2
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr11_+_7626950 0.34 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr9_-_15510989 0.34 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1
PC4 and SFRS1 interacting protein 1
chr9_-_125667618 0.34 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr3_+_107318157 0.34 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr12_-_10978957 0.34 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr6_+_52535878 0.34 ENST00000211314.4
TMEM14A
transmembrane protein 14A
chr6_-_13486369 0.34 ENST00000558378.1
AL583828.1
AL583828.1
chr7_-_22234381 0.33 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr5_-_86534822 0.33 ENST00000445770.2
AC008394.1
Uncharacterized protein
chr7_-_94285472 0.33 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr10_-_54531406 0.33 ENST00000373968.3
MBL2
mannose-binding lectin (protein C) 2, soluble
chr11_+_7618413 0.33 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr17_-_46623441 0.33 ENST00000330070.4
HOXB2
homeobox B2
chr7_-_94285511 0.33 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chrX_-_10851762 0.33 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr8_+_10530155 0.33 ENST00000521818.1
C8orf74
chromosome 8 open reading frame 74
chr6_-_41715128 0.33 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC
progastricsin (pepsinogen C)
chr16_-_31228680 0.32 ENST00000302964.3
PYDC1
PYD (pyrin domain) containing 1
chr12_+_52643077 0.32 ENST00000553310.2
ENST00000544024.1
KRT86
keratin 86
chr1_-_110933611 0.32 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr5_+_140514782 0.32 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr16_+_66586461 0.32 ENST00000264001.4
ENST00000351137.4
ENST00000345436.4
ENST00000362093.4
ENST00000417030.2
ENST00000527729.1
ENST00000532838.1
CKLF
CKLF-CMTM1
chemokine-like factor
CKLF-CMTM1 readthrough
chr2_-_79386786 0.32 ENST00000393878.1
ENST00000305165.2
ENST00000409839.3
REG3A
regenerating islet-derived 3 alpha
chr4_-_163085107 0.32 ENST00000379164.4
FSTL5
follistatin-like 5
chr20_+_62669472 0.31 ENST00000463337.1
ENST00000358393.1
LINC00176
long intergenic non-protein coding RNA 176
chr1_+_156024552 0.31 ENST00000368304.5
ENST00000368302.3
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr5_-_35195338 0.31 ENST00000509839.1
PRLR
prolactin receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.5 3.5 GO:0097338 response to clozapine(GO:0097338)
0.4 1.8 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.3 1.2 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3 1.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 0.9 GO:1904760 myofibroblast differentiation(GO:0036446) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) regulation of myofibroblast differentiation(GO:1904760)
0.3 1.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 0.8 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.3 1.0 GO:0072204 pro-T cell differentiation(GO:0002572) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) negative regulation of DNA demethylation(GO:1901536)
0.2 2.0 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 0.7 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 0.6 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.2 1.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.8 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 1.0 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 0.7 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.2 0.5 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2 0.5 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.7 GO:0072248 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.7 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 0.4 GO:1904432 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.3 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 0.6 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 0.3 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.1 0.3 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.8 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.4 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.1 0.9 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.5 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.7 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.1 0.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.8 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.8 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.2 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.1 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 1.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.4 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.2 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.4 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.3 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.3 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.4 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.6 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.3 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.8 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 0.4 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 2.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.4 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.7 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.3 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.6 GO:1902224 ketone body metabolic process(GO:1902224)
0.1 1.8 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.6 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 0.2 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.5 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.4 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.3 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 1.2 GO:0048535 lymph node development(GO:0048535)
0.0 0.3 GO:2001202 negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.0 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.0 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.4 GO:0001955 blood vessel maturation(GO:0001955)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 1.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 1.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.6 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.4 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.5 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.4 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 1.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 1.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.0 1.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.9 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.6 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 3.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
0.0 0.5 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.0 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501)
0.0 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.5 GO:0031297 replication fork processing(GO:0031297)
0.0 1.1 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.0 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.4 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.4 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.5 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.4 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 1.3 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 0.7 GO:0005608 laminin-3 complex(GO:0005608)
0.2 0.5 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.2 0.8 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.2 3.7 GO:0071564 npBAF complex(GO:0071564)
0.2 3.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.8 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 2.0 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 0.4 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0005607 laminin-1 complex(GO:0005606) laminin-2 complex(GO:0005607)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.7 GO:0016011 dystroglycan complex(GO:0016011)
0.1 0.3 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.9 GO:0000124 SAGA complex(GO:0000124)
0.1 1.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 2.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 2.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 3.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)
0.0 0.8 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.5 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.4 1.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.4 1.8 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 1.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 0.8 GO:0017129 triglyceride binding(GO:0017129)
0.2 0.7 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.2 1.0 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 3.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.8 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.7 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 0.4 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.6 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.3 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1 0.8 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 2.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.3 GO:0043398 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.1 0.3 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.1 0.6 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.3 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 0.3 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.4 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.4 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 1.3 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.2 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.2 GO:0070404 NADH binding(GO:0070404)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 3.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.2 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.5 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.0 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0046625 sphingosine-1-phosphate receptor activity(GO:0038036) sphingolipid binding(GO:0046625)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 4.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID IL3 PATHWAY IL3-mediated signaling events
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 5.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 1.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 3.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.9 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 2.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism