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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for GCUACAU

Z-value: 0.46

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miRNA associated with seed GCUACAU

NamemiRBASE accession
hsa-miR-221-3p
MIMAT0000278
hsa-miR-222-3p
MIMAT0000279

Activity profile of GCUACAU motif

Sorted Z-values of GCUACAU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_20522179 1.63 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr4_+_55524085 1.45 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr6_-_16761678 1.24 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr13_+_32605437 1.22 ENST00000380250.3
FRY
furry homolog (Drosophila)
chr15_-_52970820 1.08 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr12_+_12870055 1.07 ENST00000228872.4
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr8_-_93115445 0.89 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_43453734 0.82 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chrX_+_28605516 0.82 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr6_+_16129308 0.71 ENST00000356840.3
ENST00000349606.4
MYLIP
myosin regulatory light chain interacting protein
chr19_+_1249869 0.71 ENST00000591446.2
MIDN
midnolin
chr1_+_63833261 0.66 ENST00000371108.4
ALG6
ALG6, alpha-1,3-glucosyltransferase
chr4_+_144257915 0.66 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr3_-_124774802 0.64 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr2_+_148778570 0.59 ENST00000407073.1
MBD5
methyl-CpG binding domain protein 5
chr2_-_160472952 0.59 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr9_-_129885010 0.54 ENST00000373425.3
ANGPTL2
angiopoietin-like 2
chr2_+_235860616 0.53 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr17_-_76356148 0.46 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chr15_+_57210818 0.45 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chr14_+_77228532 0.45 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr5_-_137090028 0.41 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chrX_+_105066524 0.35 ENST00000243300.9
ENST00000428173.2
NRK
Nik related kinase
chr15_-_101792137 0.34 ENST00000254190.3
CHSY1
chondroitin sulfate synthase 1
chr11_-_94964354 0.33 ENST00000536441.1
SESN3
sestrin 3
chr4_+_144434584 0.33 ENST00000283131.3
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr1_+_97187318 0.32 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr5_+_140213815 0.31 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr5_+_140227048 0.31 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr4_-_55991752 0.31 ENST00000263923.4
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr18_-_53255766 0.31 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr5_+_140220769 0.31 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr1_+_26438289 0.30 ENST00000374271.4
ENST00000374269.1
PDIK1L
PDLIM1 interacting kinase 1 like
chr5_+_140248518 0.30 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr9_-_123476719 0.30 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr17_+_38278530 0.29 ENST00000398532.4
MSL1
male-specific lethal 1 homolog (Drosophila)
chr7_+_138916231 0.29 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr5_+_79703823 0.29 ENST00000338008.5
ENST00000510158.1
ENST00000505560.1
ZFYVE16
zinc finger, FYVE domain containing 16
chr17_-_76870222 0.27 ENST00000585421.1
TIMP2
TIMP metallopeptidase inhibitor 2
chr14_-_36278412 0.27 ENST00000389698.3
ENST00000258840.6
RALGAPA1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr16_+_12070567 0.27 ENST00000566228.1
SNX29
sorting nexin 29
chr5_+_140254884 0.26 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr15_+_39873268 0.25 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chr1_+_28696111 0.24 ENST00000373839.3
PHACTR4
phosphatase and actin regulator 4
chr9_+_36036430 0.24 ENST00000377966.3
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr1_-_156051789 0.23 ENST00000532414.2
MEX3A
mex-3 RNA binding family member A
chr7_-_27196267 0.23 ENST00000242159.3
HOXA7
homeobox A7
chr21_-_40685477 0.21 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr5_+_138678131 0.21 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr1_+_150980889 0.21 ENST00000450884.1
ENST00000271620.3
ENST00000271619.8
ENST00000368937.1
ENST00000431193.1
ENST00000368936.1
PRUNE
prune exopolyphosphatase
chr12_+_70636765 0.21 ENST00000552231.1
ENST00000229195.3
ENST00000547780.1
ENST00000418359.3
CNOT2
CCR4-NOT transcription complex, subunit 2
chr5_-_77844974 0.21 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr3_+_183353356 0.20 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24
kelch-like family member 24
chr3_-_129407535 0.20 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr8_-_52811640 0.19 ENST00000360540.5
ENST00000521344.1
PCMTD1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr8_-_60031762 0.19 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr16_+_69599861 0.18 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_+_178257372 0.18 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr14_+_75745477 0.17 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr18_+_46065393 0.17 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr20_+_56964169 0.17 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr5_+_140165876 0.17 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr16_+_22308717 0.16 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr2_+_109335929 0.15 ENST00000283195.6
RANBP2
RAN binding protein 2
chr17_-_27278304 0.15 ENST00000577226.1
PHF12
PHD finger protein 12
chr4_+_159690218 0.15 ENST00000264433.6
FNIP2
folliculin interacting protein 2
chr2_-_100106419 0.15 ENST00000393445.3
ENST00000258428.3
REV1
REV1, polymerase (DNA directed)
chr4_+_26585538 0.15 ENST00000264866.4
TBC1D19
TBC1 domain family, member 19
chr2_-_164592497 0.15 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr12_-_118498958 0.14 ENST00000315436.3
WSB2
WD repeat and SOCS box containing 2
chr1_+_220701456 0.14 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr3_+_169684553 0.14 ENST00000337002.4
ENST00000480708.1
SEC62
SEC62 homolog (S. cerevisiae)
chr8_+_26149007 0.14 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr18_+_6834472 0.13 ENST00000581099.1
ENST00000419673.2
ENST00000531294.1
ARHGAP28
Rho GTPase activating protein 28
chr5_+_140306478 0.13 ENST00000253807.2
PCDHAC1
protocadherin alpha subfamily C, 1
chr16_-_30798492 0.13 ENST00000262525.4
ZNF629
zinc finger protein 629
chr1_+_222791417 0.13 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
MIA3
melanoma inhibitory activity family, member 3
chr8_+_28747884 0.12 ENST00000287701.10
ENST00000444075.1
ENST00000403668.2
ENST00000519662.1
ENST00000558662.1
ENST00000523613.1
ENST00000560599.1
ENST00000397358.3
HMBOX1
homeobox containing 1
chr16_+_67596310 0.12 ENST00000264010.4
ENST00000401394.1
CTCF
CCCTC-binding factor (zinc finger protein)
chr1_-_150849208 0.12 ENST00000358595.5
ARNT
aryl hydrocarbon receptor nuclear translocator
chr15_-_56535464 0.12 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
RFX7
regulatory factor X, 7
chr16_-_11350036 0.11 ENST00000332029.2
SOCS1
suppressor of cytokine signaling 1
chr5_+_140207536 0.11 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr17_-_58603568 0.11 ENST00000083182.3
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr9_+_976964 0.11 ENST00000190165.2
DMRT3
doublesex and mab-3 related transcription factor 3
chr16_+_68119440 0.10 ENST00000346183.3
ENST00000329524.4
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr5_+_140186647 0.10 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr10_+_73975742 0.10 ENST00000299381.4
ANAPC16
anaphase promoting complex subunit 16
chr12_-_123011536 0.10 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr6_+_152011628 0.10 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr6_+_17281573 0.10 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr4_+_52709229 0.09 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCUN1D4
DCN1, defective in cullin neddylation 1, domain containing 4
chr5_+_56469775 0.09 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr4_-_89619386 0.09 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr3_-_28390581 0.09 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr1_-_205601064 0.09 ENST00000357992.4
ENST00000289703.4
ELK4
ELK4, ETS-domain protein (SRF accessory protein 1)
chr11_+_118754475 0.08 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr6_+_7107999 0.08 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr1_-_68698222 0.08 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr9_+_15553055 0.07 ENST00000380701.3
CCDC171
coiled-coil domain containing 171
chr9_-_3525968 0.07 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr4_-_83719983 0.06 ENST00000319540.4
SCD5
stearoyl-CoA desaturase 5
chr5_+_141488070 0.06 ENST00000253814.4
NDFIP1
Nedd4 family interacting protein 1
chr12_+_56401268 0.06 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr13_+_20532807 0.06 ENST00000382869.3
ENST00000382881.3
ZMYM2
zinc finger, MYM-type 2
chr10_-_11653753 0.06 ENST00000609104.1
USP6NL
USP6 N-terminal like
chr6_-_52441713 0.06 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr9_-_127952032 0.06 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C
protein phosphatase 6, catalytic subunit
chr3_+_182511266 0.06 ENST00000323116.5
ENST00000493826.1
ATP11B
ATPase, class VI, type 11B
chr15_-_65809581 0.06 ENST00000341861.5
DPP8
dipeptidyl-peptidase 8
chr18_-_72921303 0.05 ENST00000322342.3
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr10_+_22610124 0.05 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr2_+_46926048 0.05 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr5_-_38595498 0.05 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr6_-_111804393 0.05 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr2_+_113033164 0.05 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr1_+_86046433 0.05 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr3_+_47324424 0.05 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18
kelch-like family member 18
chrX_-_106959631 0.05 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chrX_-_109561294 0.05 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_-_48462566 0.05 ENST00000606738.2
TRABD2B
TraB domain containing 2B
chr17_-_63557759 0.04 ENST00000307078.5
AXIN2
axin 2
chr3_+_179065474 0.04 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr9_+_128509624 0.04 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr4_-_10458982 0.04 ENST00000326756.3
ZNF518B
zinc finger protein 518B
chr1_+_33283043 0.04 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP
S100P binding protein
chr9_-_34126730 0.04 ENST00000361264.4
DCAF12
DDB1 and CUL4 associated factor 12
chr5_+_161274685 0.04 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr16_+_22019404 0.04 ENST00000542527.2
ENST00000569656.1
ENST00000562695.1
C16orf52
chromosome 16 open reading frame 52
chr5_+_140180635 0.04 ENST00000522353.2
ENST00000532566.2
PCDHA3
protocadherin alpha 3
chr10_+_22605304 0.04 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr2_+_42275153 0.03 ENST00000294964.5
PKDCC
protein kinase domain containing, cytoplasmic
chr11_+_31531291 0.03 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr2_-_69870835 0.03 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr7_+_77325738 0.03 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr8_-_65711310 0.03 ENST00000310193.3
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr5_+_140261703 0.03 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr9_+_96338860 0.03 ENST00000375376.4
PHF2
PHD finger protein 2
chr14_+_53196872 0.03 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr12_-_104532062 0.03 ENST00000240055.3
NFYB
nuclear transcription factor Y, beta
chr14_-_21905395 0.03 ENST00000430710.3
ENST00000553283.1
CHD8
chromodomain helicase DNA binding protein 8
chr3_-_170626418 0.03 ENST00000474096.1
ENST00000295822.2
EIF5A2
eukaryotic translation initiation factor 5A2
chr17_+_42836329 0.02 ENST00000200557.6
ADAM11
ADAM metallopeptidase domain 11
chr10_-_99094458 0.02 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr9_-_74980113 0.02 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr10_-_94003003 0.02 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr15_+_90808919 0.02 ENST00000379095.3
NGRN
neugrin, neurite outgrowth associated
chr5_-_150948414 0.02 ENST00000261800.5
FAT2
FAT atypical cadherin 2
chr16_-_69419871 0.02 ENST00000603068.1
ENST00000254942.3
ENST00000567296.2
TERF2
telomeric repeat binding factor 2
chr14_+_105781048 0.02 ENST00000458164.2
ENST00000447393.1
PACS2
phosphofurin acidic cluster sorting protein 2
chr4_-_176923483 0.02 ENST00000280187.7
ENST00000512509.1
GPM6A
glycoprotein M6A
chr5_+_179921430 0.02 ENST00000393356.1
CNOT6
CCR4-NOT transcription complex, subunit 6
chrX_-_72434628 0.02 ENST00000536638.1
ENST00000373517.3
NAP1L2
nucleosome assembly protein 1-like 2
chr1_+_36273743 0.02 ENST00000373210.3
AGO4
argonaute RISC catalytic component 4
chr10_+_114709999 0.02 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr20_-_43438912 0.01 ENST00000541604.2
ENST00000372851.3
RIMS4
regulating synaptic membrane exocytosis 4
chr14_-_64010046 0.01 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr14_+_72399833 0.01 ENST00000553530.1
ENST00000556437.1
RGS6
regulator of G-protein signaling 6
chr9_-_111929560 0.01 ENST00000561981.2
FRRS1L
ferric-chelate reductase 1-like
chr22_+_21213259 0.01 ENST00000215730.7
SNAP29
synaptosomal-associated protein, 29kDa
chrX_+_103411189 0.01 ENST00000493442.1
FAM199X
family with sequence similarity 199, X-linked
chr2_+_208394616 0.01 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr3_-_169530452 0.01 ENST00000446859.1
LRRC34
leucine rich repeat containing 34
chr5_+_139493665 0.01 ENST00000331327.3
PURA
purine-rich element binding protein A
chr13_+_53226963 0.01 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SUGT1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr3_+_16926441 0.01 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr18_+_43753974 0.01 ENST00000282059.6
ENST00000321319.6
C18orf25
chromosome 18 open reading frame 25
chr11_+_119076745 0.01 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr3_-_71774516 0.01 ENST00000425534.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr17_+_61627814 0.01 ENST00000310827.4
ENST00000431926.1
ENST00000415273.2
DCAF7
DDB1 and CUL4 associated factor 7
chr3_-_185542817 0.01 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_60983361 0.01 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr10_+_1095416 0.01 ENST00000358220.1
WDR37
WD repeat domain 37
chr12_+_125811162 0.01 ENST00000299308.3
TMEM132B
transmembrane protein 132B
chr13_+_49550015 0.01 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr6_+_44355257 0.01 ENST00000371477.3
CDC5L
cell division cycle 5-like
chr1_+_75594119 0.01 ENST00000294638.5
LHX8
LIM homeobox 8
chr1_+_27022485 0.00 ENST00000324856.7
ARID1A
AT rich interactive domain 1A (SWI-like)
chr9_+_96214166 0.00 ENST00000375389.3
ENST00000333936.5
ENST00000340893.4
FAM120A
family with sequence similarity 120A
chr7_-_105029329 0.00 ENST00000393651.3
ENST00000460391.1
SRPK2
SRSF protein kinase 2
chr8_-_116681221 0.00 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr12_+_94542459 0.00 ENST00000258526.4
PLXNC1
plexin C1
chr4_-_87281224 0.00 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr11_-_70507901 0.00 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr2_+_111878483 0.00 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr12_+_56473628 0.00 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr12_+_62860581 0.00 ENST00000393632.2
ENST00000393630.3
ENST00000280379.6
ENST00000546600.1
ENST00000552738.1
ENST00000393629.2
ENST00000552115.1
MON2
MON2 homolog (S. cerevisiae)
chr18_-_51751132 0.00 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr11_+_70244510 0.00 ENST00000346329.3
ENST00000301843.8
ENST00000376561.3
CTTN
cortactin
chr17_-_37607497 0.00 ENST00000394287.3
ENST00000300651.6
MED1
mediator complex subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GCUACAU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.3 1.6 GO:0071321 cellular response to cGMP(GO:0071321)
0.2 0.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 1.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 0.5 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 1.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.7 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.1 0.7 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.8 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.2 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.1 0.8 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.3 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.7 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.0 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.0 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.7 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.0 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 1.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.2 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.8 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 1.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.7 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors