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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for GCUGGUG
Z-value: 0.47
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miRNA associated with seed GCUGGUG
| Name | miRBASE accession |
|---|---|
|
hsa-miR-138-5p
|
MIMAT0000430 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_-_95896550 Show fit | 0.54 |
ENST00000375446.4
|
ninjurin 1 |
|
| chr5_-_115910630 Show fit | 0.53 |
ENST00000343348.6
|
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
|
| chrX_+_9431324 Show fit | 0.51 |
ENST00000407597.2
ENST00000424279.1 ENST00000536365.1 ENST00000441088.1 ENST00000380961.1 ENST00000415293.1 |
transducin (beta)-like 1X-linked |
|
| chr14_+_21538429 Show fit | 0.48 |
ENST00000298694.4
ENST00000555038.1 |
Rho guanine nucleotide exchange factor (GEF) 40 |
|
| chr8_+_106330920 Show fit | 0.47 |
ENST00000407775.2
|
zinc finger protein, FOG family member 2 |
|
| chr9_+_118916082 Show fit | 0.45 |
ENST00000328252.3
|
pregnancy-associated plasma protein A, pappalysin 1 |
|
| chr10_+_74451883 Show fit | 0.45 |
ENST00000373053.3
ENST00000357157.6 |
mitochondrial calcium uniporter |
|
| chr4_+_47033345 Show fit | 0.45 |
ENST00000295454.3
|
gamma-aminobutyric acid (GABA) A receptor, beta 1 |
|
| chr19_+_13135386 Show fit | 0.43 |
ENST00000360105.4
ENST00000588228.1 ENST00000591028.1 |
nuclear factor I/X (CCAAT-binding transcription factor) |
|
| chr22_-_38240412 Show fit | 0.40 |
ENST00000215941.4
|
ankyrin repeat domain 54 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GCUGGUG
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.2 | 0.5 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.0 | 0.5 | GO:0060033 | anatomical structure regression(GO:0060033) |
| 0.1 | 0.4 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.0 | 0.4 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.0 | 0.4 | GO:0032354 | response to follicle-stimulating hormone(GO:0032354) |
| 0.0 | 0.4 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.1 | 0.3 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.0 | 0.3 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.0 | 0.3 | GO:0021535 | cell migration in hindbrain(GO:0021535) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 0.4 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.0 | 0.4 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 0.2 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.1 | 0.2 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.0 | 0.2 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.0 | 0.1 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.0 | 0.1 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.0 | 0.1 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.0 | 0.1 | GO:0031213 | RSF complex(GO:0031213) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.0 | 0.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.0 | 0.3 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
| 0.0 | 0.3 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.3 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 0.2 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.1 | 0.2 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.0 | 0.2 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.0 | 0.2 | GO:0038051 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.0 | 0.2 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.5 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.5 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.0 | 0.4 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.4 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.3 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.0 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |