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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for GFI1

Z-value: 1.50

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Transcription factors associated with GFI1

Gene Symbol Gene ID Gene Info
ENSG00000162676.7 growth factor independent 1 transcriptional repressor

Activity-expression correlation:

Activity profile of GFI1 motif

Sorted Z-values of GFI1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_41614909 6.95 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr9_+_2158485 6.88 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_2158443 6.51 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_41614720 6.31 ENST00000509277.1
LIM and calponin homology domains 1
chr6_+_136172820 5.68 ENST00000308191.6
phosphodiesterase 7B
chr4_+_41362796 5.67 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIM and calponin homology domains 1
chr12_-_58212487 4.97 ENST00000549994.1
advillin
chr3_+_8543393 4.73 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr4_+_42399856 4.48 ENST00000319234.4
shisa family member 3
chr1_+_61542922 4.48 ENST00000407417.3
nuclear factor I/A
chr3_+_8543561 4.06 ENST00000397386.3
LIM and cysteine-rich domains 1
chr1_+_164528866 3.91 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr5_-_88179302 3.87 ENST00000504921.2
myocyte enhancer factor 2C
chr3_+_39851094 3.87 ENST00000302541.6
myosin VIIA and Rab interacting protein
chr18_-_22932080 3.82 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
zinc finger protein 521
chr21_-_31744557 3.70 ENST00000399889.2
keratin associated protein 13-2
chr15_-_70994612 3.63 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_-_70626314 3.21 ENST00000510821.1
sulfotransferase family, cytosolic, 1B, member 1
chr19_+_36602104 3.15 ENST00000585332.1
ENST00000262637.4
ovo-like zinc finger 3
chr3_+_8543533 3.12 ENST00000454244.1
LIM and cysteine-rich domains 1
chr9_+_2159850 3.12 ENST00000416751.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_+_96875657 3.04 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr6_+_132455118 2.97 ENST00000458028.1
long intergenic non-protein coding RNA 1013
chr3_-_66024213 2.94 ENST00000483466.1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr12_+_44229846 2.86 ENST00000551577.1
ENST00000266534.3
transmembrane protein 117
chr14_-_22005062 2.85 ENST00000317492.5
spalt-like transcription factor 2
chr12_-_42877408 2.84 ENST00000552240.1
prickle homolog 1 (Drosophila)
chr2_+_66662690 2.83 ENST00000488550.1
Meis homeobox 1
chr2_+_66662510 2.82 ENST00000272369.9
ENST00000407092.2
Meis homeobox 1
chr9_-_14180778 2.56 ENST00000380924.1
ENST00000543693.1
nuclear factor I/B
chr9_+_71939488 2.44 ENST00000455972.1
family with sequence similarity 189, member A2
chr7_+_102553430 2.40 ENST00000339431.4
ENST00000249377.4
leucine rich repeat containing 17
chr15_-_52587945 2.38 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
myosin VC
chr9_-_100459639 2.37 ENST00000375128.4
xeroderma pigmentosum, complementation group A
chr1_+_162351503 2.36 ENST00000458626.2
chromosome 1 open reading frame 226
chr12_-_42877726 2.33 ENST00000548696.1
prickle homolog 1 (Drosophila)
chr6_+_132455526 2.32 ENST00000443303.1
long intergenic non-protein coding RNA 1013
chr7_-_120498357 2.30 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr2_+_234104079 2.22 ENST00000417661.1
inositol polyphosphate-5-phosphatase, 145kDa
chr14_-_22005018 2.22 ENST00000546363.1
spalt-like transcription factor 2
chr14_-_22005343 2.18 ENST00000327430.3
spalt-like transcription factor 2
chr12_-_42877764 2.12 ENST00000455697.1
prickle homolog 1 (Drosophila)
chr5_-_111091948 2.11 ENST00000447165.2
neuronal regeneration related protein
chr1_+_163039143 2.10 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
regulator of G-protein signaling 4
chr2_+_120687335 2.10 ENST00000544261.1
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr11_+_5646213 2.09 ENST00000429814.2
tripartite motif containing 34
chr6_-_52859046 2.05 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr11_+_59522532 2.04 ENST00000337979.4
ENST00000535361.1
syntaxin 3
chr5_-_88119580 2.00 ENST00000539796.1
myocyte enhancer factor 2C
chr20_-_33732952 1.96 ENST00000541621.1
ER degradation enhancer, mannosidase alpha-like 2
chr4_-_90756769 1.96 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_70626430 1.93 ENST00000310613.3
sulfotransferase family, cytosolic, 1B, member 1
chr2_+_47630108 1.92 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
mutS homolog 2
chr14_-_23285069 1.86 ENST00000554758.1
ENST00000397528.4
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr11_-_82782861 1.86 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30, member RAS oncogene family
chr17_-_66951474 1.84 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr16_+_12059050 1.81 ENST00000396495.3
tumor necrosis factor receptor superfamily, member 17
chr7_+_16793160 1.81 ENST00000262067.4
tetraspanin 13
chr12_-_59314246 1.80 ENST00000320743.3
leucine-rich repeats and immunoglobulin-like domains 3
chr16_+_12058961 1.78 ENST00000053243.1
tumor necrosis factor receptor superfamily, member 17
chr22_+_31518938 1.76 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
inositol polyphosphate-5-phosphatase J
chr14_-_23285011 1.76 ENST00000397532.3
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_61554413 1.75 ENST00000538928.1
ENST00000290866.4
ENST00000428043.1
angiotensin I converting enzyme
chr1_+_210406121 1.71 ENST00000367012.3
SERTA domain containing 4
chr20_+_45338126 1.68 ENST00000359271.2
solute carrier family 2 (facilitated glucose transporter), member 10
chr11_-_71791518 1.68 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
nuclear mitotic apparatus protein 1
chr8_+_70378852 1.67 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
sulfatase 1
chr8_+_52730143 1.66 ENST00000415643.1
Uncharacterized protein
chr7_-_27196267 1.65 ENST00000242159.3
homeobox A7
chr9_-_79520989 1.62 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
prune homolog 2 (Drosophila)
chr12_-_104443890 1.62 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
glycosyltransferase 8 domain containing 2
chr4_-_89744457 1.59 ENST00000395002.2
family with sequence similarity 13, member A
chr9_+_75263565 1.59 ENST00000396237.3
transmembrane channel-like 1
chrX_+_138612889 1.58 ENST00000218099.2
ENST00000394090.2
coagulation factor IX
chr6_+_25279651 1.57 ENST00000329474.6
leucine rich repeat containing 16A
chr21_-_40033618 1.56 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
v-ets avian erythroblastosis virus E26 oncogene homolog
chr1_+_163038565 1.53 ENST00000421743.2
regulator of G-protein signaling 4
chr19_+_55417499 1.48 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
natural cytotoxicity triggering receptor 1
chr17_-_18266765 1.46 ENST00000354098.3
serine hydroxymethyltransferase 1 (soluble)
chr1_+_154377669 1.45 ENST00000368485.3
ENST00000344086.4
interleukin 6 receptor
chr16_+_82090028 1.43 ENST00000568090.1
hydroxysteroid (17-beta) dehydrogenase 2
chr8_+_118532937 1.43 ENST00000297347.3
mediator complex subunit 30
chr2_-_160473114 1.41 ENST00000392783.2
bromodomain adjacent to zinc finger domain, 2B
chr8_-_6420565 1.40 ENST00000338312.6
angiopoietin 2
chr11_+_123986069 1.40 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
von Willebrand factor A domain containing 5A
chr9_-_34376851 1.40 ENST00000297625.7
KIAA1161
chr3_-_112329110 1.38 ENST00000479368.1
coiled-coil domain containing 80
chr8_+_95835438 1.36 ENST00000521860.1
ENST00000519457.1
ENST00000519053.1
ENST00000523731.1
ENST00000447247.1
integrator complex subunit 8
chr11_-_71791726 1.36 ENST00000393695.3
nuclear mitotic apparatus protein 1
chr6_-_7911042 1.35 ENST00000379757.4
thioredoxin domain containing 5 (endoplasmic reticulum)
chr15_+_96876340 1.34 ENST00000453270.2
nuclear receptor subfamily 2, group F, member 2
chr12_-_31158902 1.34 ENST00000544329.1
ENST00000418254.2
ENST00000222396.5
RP11-551L14.4
chr1_+_196621002 1.33 ENST00000367429.4
ENST00000439155.2
complement factor H
chr10_-_65028938 1.31 ENST00000402544.1
jumonji domain containing 1C
chr19_+_55477711 1.30 ENST00000448584.2
ENST00000537859.1
ENST00000585500.1
ENST00000427260.2
ENST00000538819.1
ENST00000263437.6
NLR family, pyrin domain containing 2
chr1_+_66258846 1.29 ENST00000341517.4
phosphodiesterase 4B, cAMP-specific
chr2_+_189839046 1.28 ENST00000304636.3
ENST00000317840.5
collagen, type III, alpha 1
chr2_+_176987088 1.26 ENST00000249499.6
homeobox D9
chr7_+_120591170 1.25 ENST00000431467.1
inhibitor of growth family, member 3
chr6_-_146285455 1.24 ENST00000367505.2
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr20_-_23066953 1.24 ENST00000246006.4
CD93 molecule
chr16_+_4838412 1.24 ENST00000589327.1
small integral membrane protein 22
chr3_-_33686743 1.24 ENST00000333778.6
ENST00000539981.1
cytoplasmic linker associated protein 2
chr8_-_6420759 1.23 ENST00000523120.1
angiopoietin 2
chr13_-_67802549 1.19 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr5_-_90679145 1.18 ENST00000265138.3
arrestin domain containing 3
chr21_+_17566643 1.17 ENST00000419952.1
ENST00000445461.2
long intergenic non-protein coding RNA 478
chr1_+_243419306 1.17 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
serologically defined colon cancer antigen 8
chr1_-_60539422 1.17 ENST00000371201.3
chromosome 1 open reading frame 87
chr8_-_6420777 1.15 ENST00000415216.1
angiopoietin 2
chr15_+_42131011 1.15 ENST00000458483.1
phospholipase A2, group IVB (cytosolic)
chr3_-_114343039 1.14 ENST00000481632.1
zinc finger and BTB domain containing 20
chr8_-_6420930 1.14 ENST00000325203.5
angiopoietin 2
chr3_-_114477962 1.13 ENST00000471418.1
zinc finger and BTB domain containing 20
chr2_+_87755054 1.12 ENST00000423846.1
long intergenic non-protein coding RNA 152
chr1_-_60539405 1.10 ENST00000450089.2
chromosome 1 open reading frame 87
chr11_-_94964354 1.10 ENST00000536441.1
sestrin 3
chr18_-_53257027 1.10 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
transcription factor 4
chr18_+_3448455 1.09 ENST00000549780.1
TGFB-induced factor homeobox 1
chr5_-_35230434 1.08 ENST00000504500.1
prolactin receptor
chr10_-_65028817 1.08 ENST00000542921.1
jumonji domain containing 1C
chr8_+_68864330 1.08 ENST00000288368.4
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr7_+_100136811 1.07 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr7_-_91763822 1.06 ENST00000003100.8
cytochrome P450, family 51, subfamily A, polypeptide 1
chr17_-_39580775 1.06 ENST00000225550.3
keratin 37
chr19_+_55476620 1.06 ENST00000543010.1
ENST00000391721.4
ENST00000339757.7
NLR family, pyrin domain containing 2
chr7_-_38948774 1.06 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr6_+_28092338 1.06 ENST00000340487.4
zinc finger and SCAN domain containing 16
chr3_-_114477787 1.05 ENST00000464560.1
zinc finger and BTB domain containing 20
chr11_-_82745238 1.05 ENST00000531021.1
RAB30, member RAS oncogene family
chr1_+_153232160 1.04 ENST00000368742.3
loricrin
chr1_+_150337144 1.03 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
regulation of nuclear pre-mRNA domain containing 2
chr7_-_91764108 1.03 ENST00000450723.1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr17_-_57184260 1.01 ENST00000376149.3
ENST00000393066.3
tripartite motif containing 37
chr2_-_46844159 0.98 ENST00000474980.1
ENST00000306465.4
phosphatidylinositol glycan anchor biosynthesis, class F
chr10_-_48416849 0.98 ENST00000249598.1
growth differentiation factor 2
chrX_-_133792480 0.97 ENST00000359237.4
placenta-specific 1
chr2_-_46844242 0.96 ENST00000281382.6
phosphatidylinositol glycan anchor biosynthesis, class F
chr6_-_146285221 0.96 ENST00000367503.3
ENST00000438092.2
ENST00000275233.7
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr19_+_55417530 0.95 ENST00000350790.5
ENST00000338835.5
ENST00000357397.5
natural cytotoxicity triggering receptor 1
chr1_+_154475446 0.94 ENST00000368480.3
tudor domain containing 10
chr17_-_18266797 0.94 ENST00000316694.3
ENST00000539052.1
serine hydroxymethyltransferase 1 (soluble)
chr12_-_118406028 0.91 ENST00000425217.1
kinase suppressor of ras 2
chr2_+_1418154 0.91 ENST00000423320.1
ENST00000382198.1
thyroid peroxidase
chr1_+_203651937 0.90 ENST00000341360.2
ATPase, Ca++ transporting, plasma membrane 4
chr2_-_11272234 0.89 ENST00000590207.1
ENST00000417697.2
ENST00000396164.1
ENST00000536743.1
ENST00000544306.1
AC062028.1
chr12_-_110011288 0.89 ENST00000540016.1
ENST00000266839.5
methylmalonic aciduria (cobalamin deficiency) cblB type
chr11_+_119056178 0.88 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZ domain containing 3
chr3_-_137851220 0.87 ENST00000236709.3
alpha-1,4-N-acetylglucosaminyltransferase
chr11_-_65548265 0.86 ENST00000532090.2
adaptor-related protein complex 5, beta 1 subunit
chr10_-_11574274 0.86 ENST00000277575.5
USP6 N-terminal like
chr2_+_233404429 0.86 ENST00000389494.3
ENST00000389492.3
cholinergic receptor, nicotinic, gamma (muscle)
chr7_-_148581360 0.85 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
enhancer of zeste homolog 2 (Drosophila)
chr2_-_160472952 0.85 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
bromodomain adjacent to zinc finger domain, 2B
chr12_+_48513009 0.85 ENST00000359794.5
ENST00000551339.1
ENST00000395233.2
ENST00000548345.1
phosphofructokinase, muscle
chr6_-_32920794 0.85 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr12_+_80603233 0.85 ENST00000547103.1
ENST00000458043.2
otogelin-like
chr12_+_80730292 0.84 ENST00000298820.3
otogelin-like
chr18_-_59854203 0.84 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
phosphatidylinositol glycan anchor biosynthesis, class N
chr1_+_162602244 0.84 ENST00000367922.3
ENST00000367921.3
discoidin domain receptor tyrosine kinase 2
chr14_-_94421923 0.83 ENST00000555507.1
ankyrin repeat and SOCS box containing 2
chrX_+_84498989 0.83 ENST00000395402.1
zinc finger protein 711
chr9_+_130830451 0.83 ENST00000373068.2
ENST00000373069.5
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr1_+_74663896 0.82 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr3_+_141457105 0.81 ENST00000480908.1
ENST00000393000.3
ring finger protein 7
chr18_-_53177984 0.81 ENST00000543082.1
transcription factor 4
chr5_+_57878859 0.81 ENST00000282878.4
RAB3C, member RAS oncogene family
chr19_-_40030861 0.80 ENST00000390658.2
EP300 interacting inhibitor of differentiation 2
chr16_+_2014993 0.80 ENST00000564014.1
small nucleolar RNA host gene 9 (non-protein coding)
chr17_+_34171081 0.80 ENST00000585577.1
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr5_+_41925325 0.80 ENST00000296812.2
ENST00000281623.3
ENST00000509134.1
F-box protein 4
chr14_-_20774092 0.80 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
tetratricopeptide repeat domain 5
chr6_-_36725157 0.79 ENST00000393189.2
copine V
chr12_-_15104040 0.79 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_47134085 0.79 ENST00000371937.4
ENST00000574428.1
ENST00000329231.4
ATP synthase mitochondrial F1 complex assembly factor 1
chr1_-_113478603 0.78 ENST00000443580.1
solute carrier family 16 (monocarboxylate transporter), member 1
chr19_+_16059818 0.78 ENST00000322107.1
olfactory receptor, family 10, subfamily H, member 4
chr2_-_111291587 0.78 ENST00000437167.1
RANBP2-like and GRIP domain containing 6
chr1_+_53068020 0.78 ENST00000361314.4
glutathione peroxidase 7
chr6_+_80816372 0.78 ENST00000545529.1
branched chain keto acid dehydrogenase E1, beta polypeptide
chrX_+_84499038 0.78 ENST00000373165.3
zinc finger protein 711
chr20_-_33999766 0.77 ENST00000349714.5
ENST00000438533.1
ENST00000359226.2
ENST00000374384.2
ENST00000374377.5
ENST00000407996.2
ENST00000424405.1
ENST00000542501.1
ENST00000397554.1
ENST00000540457.1
ENST00000374380.2
ENST00000374385.5
ubiquinol-cytochrome c reductase complex assembly factor 1
chr1_-_161039456 0.77 ENST00000368016.3
Rho GTPase activating protein 30
chr12_+_48513570 0.77 ENST00000551804.1
phosphofructokinase, muscle
chr12_-_95510743 0.77 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chr17_+_1665253 0.76 ENST00000254722.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr7_-_148581251 0.76 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
enhancer of zeste homolog 2 (Drosophila)
chr11_-_82746587 0.75 ENST00000528379.1
ENST00000534103.1
RAB30, member RAS oncogene family
chr17_-_18266660 0.74 ENST00000582653.1
ENST00000352886.6
serine hydroxymethyltransferase 1 (soluble)
chrX_+_84499081 0.74 ENST00000276123.3
zinc finger protein 711
chr1_+_81771806 0.74 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr1_-_47134101 0.73 ENST00000576409.1
ATP synthase mitochondrial F1 complex assembly factor 1
chr8_+_144451039 0.73 ENST00000289013.6
rhophilin, Rho GTPase binding protein 1
chr21_-_47648665 0.73 ENST00000450351.1
ENST00000522411.1
ENST00000356396.4
ENST00000397728.3
ENST00000457828.2
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr2_+_46844290 0.72 ENST00000238892.3
cysteine-rich PDZ-binding protein
chr17_-_7531121 0.72 ENST00000573566.1
ENST00000269298.5
spermidine/spermine N1-acetyltransferase family member 2
chr10_-_102279586 0.71 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31 homolog B (S. cerevisiae)
chr2_-_238499725 0.71 ENST00000264601.3
RAB17, member RAS oncogene family
chr12_+_113587558 0.71 ENST00000335621.6
coiled-coil domain containing 42B
chr1_-_228613026 0.71 ENST00000366696.1
histone cluster 3, H3

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.3 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
1.5 5.9 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
1.2 4.9 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
1.1 4.4 GO:0009956 radial pattern formation(GO:0009956)
1.0 3.1 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
1.0 3.0 GO:0055048 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.8 4.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.7 2.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.7 2.0 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.5 1.6 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.5 1.6 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.5 1.4 GO:0002384 hepatic immune response(GO:0002384)
0.5 11.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.4 1.7 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.4 1.7 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.4 1.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 1.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.4 2.0 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.4 2.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 1.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 2.4 GO:0048539 bone marrow development(GO:0048539)
0.3 1.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.3 1.6 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.3 1.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.3 1.5 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 2.0 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3 0.9 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 5.7 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.3 1.6 GO:0060005 vestibular reflex(GO:0060005)
0.3 0.8 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.3 1.6 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.3 3.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 1.0 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.2 0.7 GO:0097187 dentinogenesis(GO:0097187)
0.2 0.9 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.2 0.7 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 0.4 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.2 0.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 1.6 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 5.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.2 0.8 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 2.2 GO:0042908 xenobiotic transport(GO:0042908)
0.2 1.6 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.2 0.7 GO:0009447 putrescine catabolic process(GO:0009447)
0.2 0.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 0.5 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.2 5.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.2 4.6 GO:0072189 ureter development(GO:0072189)
0.2 0.7 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.2 0.5 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 2.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 0.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 0.6 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.2 0.5 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.2 2.8 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.7 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 1.7 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.7 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.1 0.4 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 0.4 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 2.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 2.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.8 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:0044209 AMP salvage(GO:0044209)
0.1 0.3 GO:0097254 renal tubular secretion(GO:0097254)
0.1 0.8 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 1.5 GO:0051775 response to redox state(GO:0051775)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.7 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 1.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 4.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.3 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.3 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 15.9 GO:0007286 spermatid development(GO:0007286)
0.1 0.8 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.7 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.4 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 1.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 1.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.3 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 0.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.1 3.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 5.0 GO:0051693 actin filament capping(GO:0051693)
0.1 3.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 1.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 1.5 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 0.4 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.8 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.3 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 1.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.5 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.4 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.2 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.2 GO:0042713 sperm ejaculation(GO:0042713)
0.1 1.2 GO:0035148 tube formation(GO:0035148)
0.1 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 1.4 GO:0016180 snRNA processing(GO:0016180)
0.1 0.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 2.4 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.1 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.4 GO:0045906 negative regulation of vasoconstriction(GO:0045906) vascular smooth muscle cell development(GO:0097084)
0.1 0.8 GO:0015866 ADP transport(GO:0015866)
0.1 1.8 GO:0010842 retina layer formation(GO:0010842)
0.0 1.9 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 1.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 1.8 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.8 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.5 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 2.1 GO:0070206 protein trimerization(GO:0070206)
0.0 2.2 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 1.5 GO:0070988 demethylation(GO:0070988)
0.0 1.6 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.5 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 8.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 5.0 GO:0031424 keratinization(GO:0031424)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.6 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.7 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 2.0 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 1.5 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 2.1 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.0 0.2 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 3.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.8 GO:0035137 hindlimb morphogenesis(GO:0035137)
0.0 1.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.6 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.1 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.2 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 1.8 GO:0021915 neural tube development(GO:0021915)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0030252 growth hormone secretion(GO:0030252)
0.0 1.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0055028 cortical microtubule(GO:0055028)
0.7 18.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.6 1.9 GO:0032302 MutSbeta complex(GO:0032302)
0.5 2.0 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.4 2.8 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.4 1.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 1.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 0.8 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 1.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 7.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 1.1 GO:0033263 CORVET complex(GO:0033263)
0.2 3.6 GO:0031045 dense core granule(GO:0031045)
0.2 0.7 GO:0097224 sperm connecting piece(GO:0097224)
0.2 2.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.0 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.5 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 1.6 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.7 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.7 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 1.4 GO:0032039 integrator complex(GO:0032039)
0.1 1.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.4 GO:0045120 pronucleus(GO:0045120)
0.1 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.8 GO:0043203 axon hillock(GO:0043203)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:1990246 uniplex complex(GO:1990246)
0.1 0.2 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 2.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 3.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.8 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 1.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 1.8 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.7 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 2.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 3.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 2.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 2.4 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 2.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 1.3 GO:0005604 basement membrane(GO:0005604)
0.0 1.7 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0032090 Pyrin domain binding(GO:0032090)
0.6 1.9 GO:0000406 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.6 3.1 GO:0070905 serine binding(GO:0070905)
0.5 1.9 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.5 1.4 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.5 1.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.4 1.3 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.4 1.7 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.4 4.0 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.4 2.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.4 1.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3 5.9 GO:0003680 AT DNA binding(GO:0003680)
0.3 0.9 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 1.7 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.3 1.7 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3 1.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 0.8 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.2 2.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 3.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 16.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 5.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 3.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 2.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 1.6 GO:0001849 complement component C1q binding(GO:0001849)
0.2 2.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 0.5 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 0.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 1.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 0.9 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 2.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.4 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.8 GO:0004096 catalase activity(GO:0004096)
0.1 2.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 5.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 4.8 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.2 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 2.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.9 GO:0010851 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.1 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 1.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.4 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 2.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0097001 ceramide binding(GO:0097001)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.8 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 2.1 GO:0032451 demethylase activity(GO:0032451)
0.1 1.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.4 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.7 GO:0032027 myosin light chain binding(GO:0032027)
0.1 4.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.8 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.4 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.0 4.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.2 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 1.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 4.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.1 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 19.1 GO:0003779 actin binding(GO:0003779)
0.0 2.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.7 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.5 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.7 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.2 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.6 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.9 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.3 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 5.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 15.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 11.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 4.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 4.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 4.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 4.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 5.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 3.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 4.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA